Guide to the Human Genome
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Search of human proteins with 239751058

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo
sapiens]
         (462 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo ...   944   0.0  
gi|34452173 integrin alpha X precursor [Homo sapiens]                 802   0.0  
gi|62548866 integrin, alpha D precursor [Homo sapiens]                471   e-133
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]      406   e-113
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]       406   e-113
gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]      110   3e-24
gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]      110   3e-24
gi|148728188 integrin, alpha E precursor [Homo sapiens]                78   1e-14
gi|116295258 integrin alpha 2 precursor [Homo sapiens]                 68   2e-11
gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]             60   4e-09
gi|52485853 integrin, alpha 11 precursor [Homo sapiens]                59   1e-08
gi|31657142 integrin, alpha 1 precursor [Homo sapiens]                 58   2e-08
gi|52485941 integrin, alpha 9 precursor [Homo sapiens]                 56   6e-08
gi|56237029 integrin alpha 5 precursor [Homo sapiens]                  52   1e-06
gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]       50   3e-06
gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]                 50   3e-06
gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]         50   3e-06
gi|67191027 integrin alpha 4 precursor [Homo sapiens]                  49   1e-05
gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]                 47   5e-05
gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]       47   5e-05
gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]       47   5e-05
gi|38569398 integrin, alpha 10 precursor [Homo sapiens]                47   5e-05
gi|49170034 integrin, alpha 8 [Homo sapiens]                           42   0.001
gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [...    39   0.008
gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [...    39   0.013
gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]         35   0.19 
gi|38016947 complement component 5 preproprotein [Homo sapiens]        33   0.71 
gi|110227857 thiamin pyrophosphokinase 1 isoform b [Homo sapiens]      30   4.6  
gi|110815802 hypothetical protein LOC84267 [Homo sapiens]              29   7.9  

>gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo
           sapiens]
          Length = 462

 Score =  944 bits (2440), Expect = 0.0
 Identities = 462/462 (100%), Positives = 462/462 (100%)

Query: 1   MLAADAQRYFTASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDG 60
           MLAADAQRYFTASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDG
Sbjct: 1   MLAADAQRYFTASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDG 60

Query: 61  EDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFR 120
           EDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFR
Sbjct: 61  EDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFR 120

Query: 121 GGAQITFLATFDVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQLELPVKYAVYTVVSSH 180
           GGAQITFLATFDVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQLELPVKYAVYTVVSSH
Sbjct: 121 GGAQITFLATFDVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQLELPVKYAVYTVVSSH 180

Query: 181 EQFTKYLNFSESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELNQE 240
           EQFTKYLNFSESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELNQE
Sbjct: 181 EQFTKYLNFSESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELNQE 240

Query: 241 AVWMDVEVSHPQVPKDCMWLLHECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCSSE 300
           AVWMDVEVSHPQVPKDCMWLLHECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCSSE
Sbjct: 241 AVWMDVEVSHPQVPKDCMWLLHECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCSSE 300

Query: 301 KIAPPASDFLAHIQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQ 360
           KIAPPASDFLAHIQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQ
Sbjct: 301 KIAPPASDFLAHIQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQ 360

Query: 361 KKVSVVSVAEITFDTSVYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLA 420
           KKVSVVSVAEITFDTSVYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLA
Sbjct: 361 KKVSVVSVAEITFDTSVYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLA 420

Query: 421 LITAVLYKVGFFKRQYKEMMEEANGQIAPENGTQTPSPPSEK 462
           LITAVLYKVGFFKRQYKEMMEEANGQIAPENGTQTPSPPSEK
Sbjct: 421 LITAVLYKVGFFKRQYKEMMEEANGQIAPENGTQTPSPPSEK 462


>gi|34452173 integrin alpha X precursor [Homo sapiens]
          Length = 1163

 Score =  802 bits (2071), Expect = 0.0
 Identities = 412/462 (89%), Positives = 412/462 (89%), Gaps = 50/462 (10%)

Query: 1    MLAADAQRYFTASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDG 60
            MLAADAQRYFTASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDG
Sbjct: 752  MLAADAQRYFTASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDG 811

Query: 61   EDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFR 120
            EDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFR
Sbjct: 812  EDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFR 871

Query: 121  GGAQITFLATFDVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQLELPVKYAVYTVVSSH 180
            GGAQITFLATFDVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQLELPVKYAVYTVVSSH
Sbjct: 872  GGAQITFLATFDVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQLELPVKYAVYTVVSSH 931

Query: 181  EQFTKYLNFSESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELNQE 240
            EQFTKYLNFSESEEKESHVAMHRYQ           VNNLGQRDLPVSINFWVPVELNQE
Sbjct: 932  EQFTKYLNFSESEEKESHVAMHRYQ-----------VNNLGQRDLPVSINFWVPVELNQE 980

Query: 241  AVWMDVEVSHPQVPKDCMWLLHECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCSSE 300
            AVWMDVEVSHPQ                                       NPSLRCSSE
Sbjct: 981  AVWMDVEVSHPQ---------------------------------------NPSLRCSSE 1001

Query: 301  KIAPPASDFLAHIQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQ 360
            KIAPPASDFLAHIQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQ
Sbjct: 1002 KIAPPASDFLAHIQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQ 1061

Query: 361  KKVSVVSVAEITFDTSVYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLA 420
            KKVSVVSVAEITFDTSVYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLA
Sbjct: 1062 KKVSVVSVAEITFDTSVYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLA 1121

Query: 421  LITAVLYKVGFFKRQYKEMMEEANGQIAPENGTQTPSPPSEK 462
            LITAVLYKVGFFKRQYKEMMEEANGQIAPENGTQTPSPPSEK
Sbjct: 1122 LITAVLYKVGFFKRQYKEMMEEANGQIAPENGTQTPSPPSEK 1163


>gi|62548866 integrin, alpha D precursor [Homo sapiens]
          Length = 1161

 Score =  471 bits (1213), Expect = e-133
 Identities = 253/452 (55%), Positives = 306/452 (67%), Gaps = 52/452 (11%)

Query: 1    MLAADAQRYFTASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDG 60
            +LA  +Q  FTASLPFEKNCG D +C+ +LG++ SF GL++L VGS+LELN  V VWN G
Sbjct: 749  VLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVTLSFSGLQTLTVGSSLELNVIVTVWNAG 808

Query: 61   EDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFR 120
            EDSYGT ++  +PAGLS+R V+  QKQ    +L L C++ P   +G  S+ C +NH IF 
Sbjct: 809  EDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRSSRCSVNHPIFH 868

Query: 121  GGAQITFLATFDVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQLELPVKYAVYTVVSSH 180
             G+  TF+ TFDVS KA LGDR+L+ A+ SSENN   +SK TFQLELPVKYAVYT++S  
Sbjct: 869  EGSNGTFIVTFDVSYKATLGDRMLMRASASSENNKASSSKATFQLELPVKYAVYTMISRQ 928

Query: 181  EQFTKYLNFSESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELNQE 240
            E+ TKY NF+ S+EK+   A HRY+           VNNL QRDL +SINFWVPV LN  
Sbjct: 929  EESTKYFNFATSDEKKMKEAEHRYR-----------VNNLSQRDLAISINFWVPVLLNGV 977

Query: 241  AVWMDVEVSHPQVPKDCMWLLHECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCSSE 300
            AVW DV +  P                                        + SL C SE
Sbjct: 978  AVW-DVVMEAP----------------------------------------SQSLPCVSE 996

Query: 301  KIAPPASDFLAHIQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQ 360
            +  P  SDFL  I ++P+LDCSIA CL+FRCDVPSFSVQEELDFTLKGNLSFGWVR+ LQ
Sbjct: 997  RKPPQHSDFLTQISRSPMLDCSIADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQ 1056

Query: 361  KKVSVVSVAEITFDTSVYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLA 420
            KKV VVSVAEITFDTSVYSQLPGQEAFMRAQ   VLE+ +V+N  P+I+GSS+G LLLLA
Sbjct: 1057 KKVLVVSVAEITFDTSVYSQLPGQEAFMRAQMEMVLEEDEVYNAIPIIMGSSVGALLLLA 1116

Query: 421  LITAVLYKVGFFKRQYKEMMEEANGQIAPENG 452
            LITA LYK+GFFKR YKEM+E+     A  +G
Sbjct: 1117 LITATLYKLGFFKRHYKEMLEDKPEDTATFSG 1148


>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
          Length = 1153

 Score =  406 bits (1043), Expect = e-113
 Identities = 231/444 (52%), Positives = 279/444 (62%), Gaps = 53/444 (11%)

Query: 1    MLAADAQRYFTASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDG 60
            +LA DAQR FTA  PFEKNCG D+ICQD+L I+FSF  L  L+VG   E N  V V NDG
Sbjct: 752  VLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPREFNVTVTVRNDG 811

Query: 61   EDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVG--SQGTWSTSCRINHLI 118
            EDSY T +TF  P  LSYR V+  Q Q   RS  L C+SA     S    STSC INH I
Sbjct: 812  EDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPI 871

Query: 119  FRGGAQITFLATFDVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQLELPVKYAVYTVVS 178
            F   +++TF  TFDV  KA LG++LLL ANV+SENN PRT+KT FQLELPVKYAVY VV+
Sbjct: 872  FPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVKYAVYMVVT 931

Query: 179  SHEQFTKYLNFSESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELN 238
            SH   TKYLNF+ S E  S V  H+YQ           V+NLGQR LP+S+ F VPV LN
Sbjct: 932  SHGVSTKYLNFTAS-ENTSRVMQHQYQ-----------VSNLGQRSLPISLVFLVPVRLN 979

Query: 239  QEAVWMDVEVSHPQVPKDCMWLLHECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCS 298
            Q  +W       PQV                                   F +N S  C 
Sbjct: 980  QTVIW-----DRPQV----------------------------------TFSENLSSTCH 1000

Query: 299  SEKIAPPASDFLAHIQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQI 358
            +++  P  SDFLA ++K PV++CSIA C R +CD+P F +QEE + TLKGNLSF W  + 
Sbjct: 1001 TKERLPSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKT 1060

Query: 359  LQKKVSVVSVAEITFDTSVYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLL 418
                + +VS AEI F+ SV++ LPGQ AF+R+QT T +E ++V NP PLIVGSS+GGLLL
Sbjct: 1061 SHNHLLIVSTAEILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLL 1120

Query: 419  LALITAVLYKVGFFKRQYKEMMEE 442
            LALITA LYK+GFFKRQYK+MM E
Sbjct: 1121 LALITAALYKLGFFKRQYKDMMSE 1144


>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
          Length = 1152

 Score =  406 bits (1043), Expect = e-113
 Identities = 231/444 (52%), Positives = 279/444 (62%), Gaps = 53/444 (11%)

Query: 1    MLAADAQRYFTASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDG 60
            +LA DAQR FTA  PFEKNCG D+ICQD+L I+FSF  L  L+VG   E N  V V NDG
Sbjct: 751  VLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPREFNVTVTVRNDG 810

Query: 61   EDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVG--SQGTWSTSCRINHLI 118
            EDSY T +TF  P  LSYR V+  Q Q   RS  L C+SA     S    STSC INH I
Sbjct: 811  EDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPI 870

Query: 119  FRGGAQITFLATFDVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQLELPVKYAVYTVVS 178
            F   +++TF  TFDV  KA LG++LLL ANV+SENN PRT+KT FQLELPVKYAVY VV+
Sbjct: 871  FPENSEVTFNITFDVDSKASLGNKLLLKANVTSENNMPRTNKTEFQLELPVKYAVYMVVT 930

Query: 179  SHEQFTKYLNFSESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELN 238
            SH   TKYLNF+ S E  S V  H+YQ           V+NLGQR LP+S+ F VPV LN
Sbjct: 931  SHGVSTKYLNFTAS-ENTSRVMQHQYQ-----------VSNLGQRSLPISLVFLVPVRLN 978

Query: 239  QEAVWMDVEVSHPQVPKDCMWLLHECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCS 298
            Q  +W       PQV                                   F +N S  C 
Sbjct: 979  QTVIW-----DRPQV----------------------------------TFSENLSSTCH 999

Query: 299  SEKIAPPASDFLAHIQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQI 358
            +++  P  SDFLA ++K PV++CSIA C R +CD+P F +QEE + TLKGNLSF W  + 
Sbjct: 1000 TKERLPSHSDFLAELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKT 1059

Query: 359  LQKKVSVVSVAEITFDTSVYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLL 418
                + +VS AEI F+ SV++ LPGQ AF+R+QT T +E ++V NP PLIVGSS+GGLLL
Sbjct: 1060 SHNHLLIVSTAEILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPNPLPLIVGSSVGGLLL 1119

Query: 419  LALITAVLYKVGFFKRQYKEMMEE 442
            LALITA LYK+GFFKRQYK+MM E
Sbjct: 1120 LALITAALYKLGFFKRQYKDMMSE 1143


>gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]
          Length = 1086

 Score =  110 bits (275), Expect = 3e-24
 Identities = 121/441 (27%), Positives = 180/441 (40%), Gaps = 78/441 (17%)

Query: 11   TASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITF 70
            T  +PFEKNCG D  C+ NL +SFS    ++L + +   L+ E+ + N  ED+Y   +  
Sbjct: 678  TWEIPFEKNCGEDKKCEANLRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDL 737

Query: 71   SHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQ-GTWSTSCRINHLIFRGGAQITFLA 129
              P GLS+R V   +   Q   + ++C+  P  S+  + + SC ++  IF+ G  +    
Sbjct: 738  HFPPGLSFRKVEMLKPHSQ---IPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQM 794

Query: 130  TFDVSPKAVLGDRLLLTANVSSENN----TPRTSKTTFQLELPVKYAVYTVVSSHEQFTK 185
             F+    +  GD + L ANV+  N         S TT    +P+ Y +  ++   E  T 
Sbjct: 795  MFNTLVNSSWGDSVELHANVTCNNEDSDLLEDNSATTI---IPILYPINILIQDQEDSTL 851

Query: 186  YLNFSESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELNQEAVWMD 245
            Y++F+    K  H   H YQ                 R  P   +  +P         ++
Sbjct: 852  YVSFTPKGPK-IHQVKHMYQV----------------RIQPSIHDHNIPT--------LE 886

Query: 246  VEVSHPQVPKDCMWLLHECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCSSEKIAPP 305
              V  PQ P +              +   W   V  E  V C +     L  ++E   P 
Sbjct: 887  AVVGVPQPPSE------------GPITHQW--SVQMEPPVPCHYEDLERLPDAAEPCLPG 932

Query: 306  ASDFLAHIQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQI-LQKKVS 364
            A                      FRC V     ++E+   + G L    V +I      S
Sbjct: 933  A---------------------LFRCPV---VFRQEILVQVIGTLEL--VGEIEASSMFS 966

Query: 365  VVSVAEITFDTSVYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLALITA 424
            + S   I+F++S +  L G  A + AQ    ++         L V S IGGLLLL LI  
Sbjct: 967  LCSSLSISFNSSKHFHLYGSNASL-AQVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFI 1025

Query: 425  VLYKVGFFKRQYKEMMEEANG 445
            VLYKVGFFKR  KE ME   G
Sbjct: 1026 VLYKVGFFKRNLKEKMEAGRG 1046


>gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]
          Length = 1170

 Score =  110 bits (275), Expect = 3e-24
 Identities = 121/441 (27%), Positives = 180/441 (40%), Gaps = 78/441 (17%)

Query: 11   TASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITF 70
            T  +PFEKNCG D  C+ NL +SFS    ++L + +   L+ E+ + N  ED+Y   +  
Sbjct: 762  TWEIPFEKNCGEDKKCEANLRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDL 821

Query: 71   SHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQ-GTWSTSCRINHLIFRGGAQITFLA 129
              P GLS+R V   +   Q   + ++C+  P  S+  + + SC ++  IF+ G  +    
Sbjct: 822  HFPPGLSFRKVEMLKPHSQ---IPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQM 878

Query: 130  TFDVSPKAVLGDRLLLTANVSSENN----TPRTSKTTFQLELPVKYAVYTVVSSHEQFTK 185
             F+    +  GD + L ANV+  N         S TT    +P+ Y +  ++   E  T 
Sbjct: 879  MFNTLVNSSWGDSVELHANVTCNNEDSDLLEDNSATTI---IPILYPINILIQDQEDSTL 935

Query: 186  YLNFSESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELNQEAVWMD 245
            Y++F+    K  H   H YQ                 R  P   +  +P         ++
Sbjct: 936  YVSFTPKGPK-IHQVKHMYQV----------------RIQPSIHDHNIPT--------LE 970

Query: 246  VEVSHPQVPKDCMWLLHECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCSSEKIAPP 305
              V  PQ P +              +   W   V  E  V C +     L  ++E   P 
Sbjct: 971  AVVGVPQPPSE------------GPITHQW--SVQMEPPVPCHYEDLERLPDAAEPCLPG 1016

Query: 306  ASDFLAHIQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQI-LQKKVS 364
            A                      FRC V     ++E+   + G L    V +I      S
Sbjct: 1017 A---------------------LFRCPV---VFRQEILVQVIGTLEL--VGEIEASSMFS 1050

Query: 365  VVSVAEITFDTSVYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLALITA 424
            + S   I+F++S +  L G  A + AQ    ++         L V S IGGLLLL LI  
Sbjct: 1051 LCSSLSISFNSSKHFHLYGSNASL-AQVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFI 1109

Query: 425  VLYKVGFFKRQYKEMMEEANG 445
            VLYKVGFFKR  KE ME   G
Sbjct: 1110 VLYKVGFFKRNLKEKMEAGRG 1130


>gi|148728188 integrin, alpha E precursor [Homo sapiens]
          Length = 1179

 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 95/442 (21%), Positives = 174/442 (39%), Gaps = 89/442 (20%)

Query: 14   LPFEKNCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITFSHP 73
            LP+EK C     C   L ++ +    + L+VG   EL   + + N GEDSY T++  ++P
Sbjct: 817  LPYEKACKNKLFCVAELQLATTV-SQQELVVGLTKELTLNINLTNSGEDSYMTSMALNYP 875

Query: 74   AGLSYRYVAEGQKQGQLRSLHLTCDSA-PVGSQGTWSTSCRINHLIF-RGGAQITFLATF 131
              L  + + +        S ++ CD   PV S      +CRI H +  R  A ++ +  +
Sbjct: 876  RNLQLKRMQKPP------SPNIQCDDPQPVAS--VLIMNCRIGHPVLKRSSAHVSVV--W 925

Query: 132  DVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQLELPVKYAVYTVVSSHEQFTKYLNFSE 191
             +   A       +T  V++ N     +  T  L+   ++    V+S       Y+N  +
Sbjct: 926  QLEENAFPNRTADITVTVTNSNERRSLANETHTLQF--RHGFVAVLSKPS--IMYVNTGQ 981

Query: 192  SEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELNQEAVWMDVEVSHP 251
                      H +           G N  G       +   VP +L    V    +++  
Sbjct: 982  GLSHHKEFLFHVH-----------GENLFGAE---YQLQICVPTKLRGLQVVAVKKLTRT 1027

Query: 252  QVPKDCMWLLHECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCSSEKIAPPASDFLA 311
            Q    C W                                      S E+    +S  + 
Sbjct: 1028 QASTVCTW--------------------------------------SQERACAYSS--VQ 1047

Query: 312  HIQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKKVSVVSVAEI 371
            H+++   + C IA               ++ + T+   +S+    ++L+    +  + EI
Sbjct: 1048 HVEEWHSVSCVIAS--------------DKENVTVAAEISWDHSEELLKDVTELQILGEI 1093

Query: 372  TFDTSVYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLALITAVLYKVGF 431
            +F+ S+Y  L  +    R + T V  K + ++  P+I+  S+GGLL+L +I  +L+K GF
Sbjct: 1094 SFNKSLYEGLNAENH--RTKITVVFLKDEKYHSLPIIIKGSVGGLLVLIVILVILFKCGF 1151

Query: 432  FKRQYKEMMEEA--NGQIAPEN 451
            FKR+Y+++  E+    Q+  EN
Sbjct: 1152 FKRKYQQLNLESIRKAQLKSEN 1173


>gi|116295258 integrin alpha 2 precursor [Homo sapiens]
          Length = 1181

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 98/437 (22%), Positives = 170/437 (38%), Gaps = 62/437 (14%)

Query: 13   SLPFEKNCGADHICQDNLGISF-SFPGLKS---LLVGSNLELNAEVMVWNDGEDSYGTTI 68
            S+PF K+CG D +C  +L +     P  +    ++   N  L   V + N  E +Y T I
Sbjct: 782  SIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFIVSNQNKRLTFSVTLKNKRESAYNTGI 841

Query: 69   TFSHPAGL---SYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFRGGAQI 125
                   L   S+    +G +        +TC  A   SQ   S +C + +   +   Q+
Sbjct: 842  VVDFSENLFFASFSLPVDGTE--------VTCQVA--ASQK--SVACDVGYPALKREQQV 889

Query: 126  TFLATFDVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQLELPVKYAVYTVVSSHEQFTK 185
            TF   FD + +  L ++  L+    SE+     +     L++P+ Y        H   + 
Sbjct: 890  TFTINFDFNLQN-LQNQASLSFQALSESQEENKADNLVNLKIPLLYDA----EIHLTRST 944

Query: 186  YLNFSE-SEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELNQEAVWM 244
             +NF E S +      +H ++                  D+     F + V      V M
Sbjct: 945  NINFYEISSDGNVPSIVHSFE------------------DVGPKFIFSLKVTTGSVPVSM 986

Query: 245  DVEVSH-PQVPKDCMWLLHECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCSSEKIA 303
               + H PQ  K+   L+     YL  +      D+       C    NP     +    
Sbjct: 987  ATVIIHIPQYTKEKNPLM-----YLTGVQTDKAGDIS------CNADINPLKIGQTSSSV 1035

Query: 304  PPASDFLAHIQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKKV 363
               S+   H ++   L+C  A C    C +    ++ E    +   +  G       + V
Sbjct: 1036 SFKSENFRHTKE---LNCRTASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFASSTFQTV 1092

Query: 364  SVVSVAEI-TFDTSVYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLALI 422
             + + AEI T++  +Y     ++  +      +    K   PT +I+GS I G+LLL  +
Sbjct: 1093 QLTAAAEINTYNPEIYVI---EDNTVTIPLMIMKPDEKAEVPTGVIIGSIIAGILLLLAL 1149

Query: 423  TAVLYKVGFFKRQYKEM 439
             A+L+K+GFFKR+Y++M
Sbjct: 1150 VAILWKLGFFKRKYEKM 1166


>gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]
          Length = 1039

 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 92/439 (20%), Positives = 172/439 (39%), Gaps = 51/439 (11%)

Query: 19   NCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITFSHPAGLSY 78
            +CG D +C   L ++ S  G   LLVG++  L  ++   N+GE +Y   +    P G  Y
Sbjct: 632  DCGEDDVCVPQLQLTASVTG-SPLLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHY 690

Query: 79   RYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFRGGAQITFLATFDVSPKAV 138
                   +  +     L C+        T    C + + + +  AQI       V     
Sbjct: 691  MRALSNVEGFE----RLICNQKKENE--TRVVLCELGNPM-KKNAQIGIAMLVSVGNLEE 743

Query: 139  LGDRLLLTANVSSENNTPRTSKTTFQLELPVKYAVYTVVSSHEQFTKYLNFSESEEKESH 198
             G+ +     + S+N+    SK    L++PV+      +  +      +  +E  E+E +
Sbjct: 744  AGESVSFQLQIRSKNSQNPNSKIVL-LDVPVRAEAQVELRGNSFPASLVVAAEEGEREQN 802

Query: 199  V-------AMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELNQEAVWMDVEVSHP 251
                      H Y+      G   G++        +SI+     + +     +D++   P
Sbjct: 803  SLDSWGPKVEHTYELHNNGPGTVNGLH--------LSIHLPGQSQPSDLLYILDIQ---P 851

Query: 252  QVPKDCMWLLHECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSL-RCSSEKIAPPASDFL 310
            Q    C       P  +D     W   +P+ +      P +P+  +    +I  P  +  
Sbjct: 852  QGGLQCFPQPPVNPLKVD-----WGLPIPSPS------PIHPAHHKRDRRQIFLPEPEQP 900

Query: 311  AHIQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKKVS---VVS 367
            + +Q   ++ C  A C   +CD+   +  +    T+   L+F W+  + Q+ +    + S
Sbjct: 901  SRLQDPVLVSCDSAPCTVVQCDLQEMARGQRAMVTV---LAFLWLPSLYQRPLDQFVLQS 957

Query: 368  VAEITFDTSVYS----QLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLALIT 423
             A     +  Y+     LP  EA +  Q    LE+  +  P   ++   +GGLLLL ++ 
Sbjct: 958  HAWFNVSSLPYAVPPLSLPRGEAQVWTQLLRALEERAI--PIWWVLVGVLGGLLLLTILV 1015

Query: 424  AVLYKVGFFKRQYKEMMEE 442
              ++KVGFFKR    + E+
Sbjct: 1016 LAMWKVGFFKRNRPPLEED 1034


>gi|52485853 integrin, alpha 11 precursor [Homo sapiens]
          Length = 1188

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 91/414 (21%), Positives = 161/414 (38%), Gaps = 65/414 (15%)

Query: 27   QDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITFSHPAGLSYRYVAEGQK 86
            QD    + SF     ++  +   +  E  + N GE++Y T +  S  A L +  +   QK
Sbjct: 815  QDCSAYTLSFDTTVFIIESTRQRVAVEATLENRGENAYSTVLNISQSANLQFASLI--QK 872

Query: 87   QGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFRGGAQITFLATFDVSPKAVLGDRLLLT 146
            +    S+    +   +  Q      C +++  FR  A++ F   F+ S K++    L + 
Sbjct: 873  EDSDGSIECVNEERRLQKQ-----VCNVSYPFFRAKAKVAFRLDFEFS-KSIFLHHLEIE 926

Query: 147  ANVSSENNTPRTSK--TTFQLELPVKYAVYTVVSSHEQFTKYLNFSESEEKESHVAMHRY 204
                S++N   ++K      L   +KY    +      FT+  + S  E K +  ++ RY
Sbjct: 927  LAAGSDSNERDSTKEDNVAPLRFHLKYEADVL------FTRSSSLSHYEVKPNS-SLERY 979

Query: 205  QAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELNQEAVWMDVEVSHPQVPKDCMWLLHEC 264
               G        + NLG            P+        M ++++ P   +    LL   
Sbjct: 980  DGIGPPFSCIFRIQNLGL----------FPIH------GMMMKITIPIATRSGNRLLKLR 1023

Query: 265  PFYLDSL---CPMWVPDVPAETLVLCIFPQNPSLRCSSEKIAPPASDFLAHIQKNPVLDC 321
             F  D     C +W                      S+E    P  + L   ++ P L+ 
Sbjct: 1024 DFLTDEANTSCNIWGN--------------------STEYRPTPVEEDL---RRAPQLNH 1060

Query: 322  SIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKKVSVVSV-AEITFDTSVYSQ 380
            S +  +   C++      +E++F L GNL   W+R +   K   + +          +S 
Sbjct: 1061 SNSDVVSINCNI-RLVPNQEINFHLLGNL---WLRSLKALKYKSMKIMVNAALQRQFHSP 1116

Query: 381  LPGQEAFMRAQTTTVLEKYKVHN-PTPLIVGSSIGGLLLLALITAVLYKVGFFK 433
               +E     Q    + K +    P  +IVGS++GGLLLLAL+   L+K+GFF+
Sbjct: 1117 FIFREEDPSRQIVFEISKQEDWQVPIWIIVGSTLGGLLLLALLVLALWKLGFFR 1170


>gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
          Length = 1179

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 90/451 (19%), Positives = 174/451 (38%), Gaps = 95/451 (21%)

Query: 14   LPFEKNCGADHICQDNLGISFSFPGLKSLLVGS-NLELNAEVMVWNDGEDSYGTTITFSH 72
            +PF K+CG    C  +L +  +      L+V S N + N  + V N  + +Y T     +
Sbjct: 802  IPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHY 861

Query: 73   PAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFRGGAQITFLATFD 132
               L +  +   QK         +C+S         + +C++ +   R G  +TF   F 
Sbjct: 862  SPNLVFSGIEAIQKD--------SCES-------NHNITCKVGYPFLRRGEMVTFKILFQ 906

Query: 133  VSPKAVLGD-RLLLTANVSSENNTPRTSKTTFQLELPVKYAV-----------YTVVSSH 180
             +   ++ +  + L+A   SE      S     + +PVKY V           +  ++++
Sbjct: 907  FNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAAN 966

Query: 181  EQFTKYLNFSESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELNQE 240
            E   + +N +E    E ++     ++G           +    +L +SI+F   +  N  
Sbjct: 967  ETVPEVINSTEDIGNEINIFYLIRKSG-----------SFPMPELKLSISF-PNMTSNGY 1014

Query: 241  AVWMDVEVSHPQVPKDCMWLLHECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCSSE 300
             V     +S  +   +C   + E PF ++S                        +  S++
Sbjct: 1015 PVLYPTGLSSSE-NANCRPHIFEDPFSINS---------------------GKKMTTSTD 1052

Query: 301  KIAPPASDFLAHIQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQ 360
                       H+++  +LDC+        C++ S  + +        N+S      IL 
Sbjct: 1053 -----------HLKRGTILDCNTCKFATITCNLTSSDISQV-------NVSL-----ILW 1089

Query: 361  KKVSVVSVAEITFDTSVYSQLPGQEAFM-------RAQTTTVLEKYKVHNPTPL--IVGS 411
            K   + S    + + ++  +L  + A +       + +    + K  +    PL  I+ S
Sbjct: 1090 KPTFIKSYFS-SLNLTIRGELRSENASLVLSSSNQKRELAIQISKDGLPGRVPLWVILLS 1148

Query: 412  SIGGLLLLALITAVLYKVGFFKRQYKEMMEE 442
            +  GLLLL L+   L+K+GFFKR  K+ ME+
Sbjct: 1149 AFAGLLLLMLLILALWKIGFFKRPLKKKMEK 1179


>gi|52485941 integrin, alpha 9 precursor [Homo sapiens]
          Length = 1035

 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 94/447 (21%), Positives = 176/447 (39%), Gaps = 67/447 (14%)

Query: 16   FEKNC-----GADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITF 70
            FE+NC      AD   Q  L +S        L +G+   ++  + + N G+D+Y   ++F
Sbjct: 616  FERNCRSEDCAADLQLQGKLLLSSMDEKTLYLALGAVKNISLNISISNLGDDAYDANVSF 675

Query: 71   SHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFRGGAQITFLAT 130
            +    L +  + + ++ G      ++C+             C +     R  ++  F   
Sbjct: 676  NVSRELFFINMWQKEEMG------ISCELLESDF-----LKCSVGFPFMRSKSKYEFSVI 724

Query: 131  FDVSPKAVLGDRLLLTANVSSEN-NTPRTSK---TTFQLELPVKYAVYTVVSSHEQFTKY 186
            FD S  +  G+  +L+  V++++ NT R+      T  L +P+ + V T ++     T +
Sbjct: 725  FDTSHLS--GEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTSF 782

Query: 187  LNFSESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLP---VSINFWVPVELNQEAVW 243
            + + ES +  + + +   +           V N G   LP   VSI+F   +      ++
Sbjct: 783  V-YGESVDAANFIQLDDLECHFQPINITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEMF 841

Query: 244  MDVEVSHPQVPKDCMWLLHECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCSSEKIA 303
               E+   Q   +C +  +  P                     CI PQ        E I 
Sbjct: 842  HVQEMVVGQEKGNCSFQKNPTP---------------------CIIPQE------QENIF 874

Query: 304  PPASDFLAHIQKNPVLDCSIAG--CLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQK 361
                 F     +  VLDC   G  CL   C+  + + +E     +   L+   +++    
Sbjct: 875  HTIFAFFTKSGRK-VLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSS 933

Query: 362  KVSVVSVAEITFDTS--VYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVG-----SSIG 414
             +  +S A++  D +  V     G       + T V E      P   +VG     S + 
Sbjct: 934  VIQFMSRAKVKVDPALRVVEIAHGNPE----EVTVVFEALHNLEPRGYVVGWIIAISLLV 989

Query: 415  GLLLLALITAVLYKVGFFKRQYKEMME 441
            G+L+  L+  +L+K+GFF+R+YKE++E
Sbjct: 990  GILIFLLLAVLLWKMGFFRRRYKEIIE 1016


>gi|56237029 integrin alpha 5 precursor [Homo sapiens]
          Length = 1049

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 48/159 (30%), Positives = 70/159 (44%), Gaps = 15/159 (9%)

Query: 294  SLRCSSEKIAPPASDFLAHIQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFG 353
            SL    ++ AP  S   +  Q   +L C  A C R RC++     QE     L   +   
Sbjct: 887  SLHHQQKREAPSRSSASSGPQ---ILKCPEAECFRLRCELGPLHQQESQSLQLHFRV--- 940

Query: 354  WVRQILQKKVSVVSV-AEITFDT--SVYSQLPGQEAFMRAQTTTVLEKYKVHN----PTP 406
            W +  LQ++    S+  E  +      Y  LP Q      Q  T ++  K       P  
Sbjct: 941  WAKTFLQREHQPFSLQCEAVYKALKMPYRILPRQLPQKERQVATAVQWTKAEGSYGVPLW 1000

Query: 407  LIVGSSIGGLLLLALITAVLYKVGFFKRQ--YKEMMEEA 443
            +I+ + + GLLLL L+  +LYK+GFFKR   Y   ME+A
Sbjct: 1001 IIILAILFGLLLLGLLIYILYKLGFFKRSLPYGTAMEKA 1039


>gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]
          Length = 1012

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 92/454 (20%), Positives = 168/454 (37%), Gaps = 56/454 (12%)

Query: 19   NCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITFSHPAGLSY 78
            +CG D++C+  L +S      K + +G +  L   V   N GE +Y   +  S P    +
Sbjct: 589  DCGEDNVCKPKLEVSVD-SDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADF 647

Query: 79   RYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFRGGAQITFLATFDVSPKAV 138
              V    +        L+C  A      T    C + + + + G Q+     F V  ++ 
Sbjct: 648  IGVVRNNEA----LARLSC--AFKTENQTRQVVCDLGNPM-KAGTQLLAGLRFSVHQQSE 700

Query: 139  LGDRLLLTANVSSENNTPRTSKT-TFQLELPVKYAVYT--VVSSHEQFTKYLNFS----- 190
            +   +     + S N   + S   + +++L V  AV    V S    F    N+      
Sbjct: 701  MDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENP 760

Query: 191  ESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELNQEAVWMDVEVSH 250
            E+EE    V  H Y+        ++             ++   P + N   +        
Sbjct: 761  ETEEDVGPVVQHIYELRNNGPSSFS----------KAMLHLQWPYKYNNNTL-------- 802

Query: 251  PQVPKDCMWLLH-ECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCSSEKIAPPASDF 309
                   +++LH +    ++    M +  +  +   L    +N ++    E+        
Sbjct: 803  -------LYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRD 855

Query: 310  LAHIQKN-PVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKK-----V 363
            LA  + +   L C +A CL+  C V      +     +K  L   W    + K+      
Sbjct: 856  LALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLL---WTETFMNKENQNHSY 912

Query: 364  SVVSVAEITFDTSVYSQLPGQE----AFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLL 419
            S+ S A        Y  LP ++      +    T  ++   +  P  +I+ + + GLLLL
Sbjct: 913  SLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLL 972

Query: 420  ALITAVLYKVGFFKRQYKEMMEEANGQIAP-ENG 452
            A++  V+Y++GFFKR      E+   Q+ P ENG
Sbjct: 973  AVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENG 1006


>gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]
          Length = 1002

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 92/454 (20%), Positives = 168/454 (37%), Gaps = 56/454 (12%)

Query: 19  NCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITFSHPAGLSY 78
           +CG D++C+  L +S      K + +G +  L   V   N GE +Y   +  S P    +
Sbjct: 579 DCGEDNVCKPKLEVSVD-SDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADF 637

Query: 79  RYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFRGGAQITFLATFDVSPKAV 138
             V    +        L+C  A      T    C + + + + G Q+     F V  ++ 
Sbjct: 638 IGVVRNNEA----LARLSC--AFKTENQTRQVVCDLGNPM-KAGTQLLAGLRFSVHQQSE 690

Query: 139 LGDRLLLTANVSSENNTPRTSKT-TFQLELPVKYAVYT--VVSSHEQFTKYLNFS----- 190
           +   +     + S N   + S   + +++L V  AV    V S    F    N+      
Sbjct: 691 MDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENP 750

Query: 191 ESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELNQEAVWMDVEVSH 250
           E+EE    V  H Y+        ++             ++   P + N   +        
Sbjct: 751 ETEEDVGPVVQHIYELRNNGPSSFS----------KAMLHLQWPYKYNNNTL-------- 792

Query: 251 PQVPKDCMWLLH-ECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCSSEKIAPPASDF 309
                  +++LH +    ++    M +  +  +   L    +N ++    E+        
Sbjct: 793 -------LYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRD 845

Query: 310 LAHIQKN-PVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKK-----V 363
           LA  + +   L C +A CL+  C V      +     +K  L   W    + K+      
Sbjct: 846 LALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLL---WTETFMNKENQNHSY 902

Query: 364 SVVSVAEITFDTSVYSQLPGQE----AFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLL 419
           S+ S A        Y  LP ++      +    T  ++   +  P  +I+ + + GLLLL
Sbjct: 903 SLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLL 962

Query: 420 ALITAVLYKVGFFKRQYKEMMEEANGQIAP-ENG 452
           A++  V+Y++GFFKR      E+   Q+ P ENG
Sbjct: 963 AVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENG 996


>gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]
          Length = 1048

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 92/454 (20%), Positives = 168/454 (37%), Gaps = 56/454 (12%)

Query: 19   NCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITFSHPAGLSY 78
            +CG D++C+  L +S      K + +G +  L   V   N GE +Y   +  S P    +
Sbjct: 625  DCGEDNVCKPKLEVSVD-SDQKKIYIGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADF 683

Query: 79   RYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFRGGAQITFLATFDVSPKAV 138
              V    +        L+C  A      T    C + + + + G Q+     F V  ++ 
Sbjct: 684  IGVVRNNEA----LARLSC--AFKTENQTRQVVCDLGNPM-KAGTQLLAGLRFSVHQQSE 736

Query: 139  LGDRLLLTANVSSENNTPRTSKT-TFQLELPVKYAVYT--VVSSHEQFTKYLNFS----- 190
            +   +     + S N   + S   + +++L V  AV    V S    F    N+      
Sbjct: 737  MDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLPIPNWEHKENP 796

Query: 191  ESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLPVSINFWVPVELNQEAVWMDVEVSH 250
            E+EE    V  H Y+        ++             ++   P + N   +        
Sbjct: 797  ETEEDVGPVVQHIYELRNNGPSSFS----------KAMLHLQWPYKYNNNTL-------- 838

Query: 251  PQVPKDCMWLLH-ECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCSSEKIAPPASDF 309
                   +++LH +    ++    M +  +  +   L    +N ++    E+        
Sbjct: 839  -------LYILHYDIDGPMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRD 891

Query: 310  LAHIQKN-PVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKK-----V 363
            LA  + +   L C +A CL+  C V      +     +K  L   W    + K+      
Sbjct: 892  LALSEGDIHTLGCGVAQCLKIVCQVGRLDRGKSAILYVKSLL---WTETFMNKENQNHSY 948

Query: 364  SVVSVAEITFDTSVYSQLPGQE----AFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLL 419
            S+ S A        Y  LP ++      +    T  ++   +  P  +I+ + + GLLLL
Sbjct: 949  SLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLL 1008

Query: 420  ALITAVLYKVGFFKRQYKEMMEEANGQIAP-ENG 452
            A++  V+Y++GFFKR      E+   Q+ P ENG
Sbjct: 1009 AVLVFVMYRMGFFKRVRPPQEEQEREQLQPHENG 1042


>gi|67191027 integrin alpha 4 precursor [Homo sapiens]
          Length = 1032

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 43/186 (23%), Positives = 73/186 (39%), Gaps = 11/186 (5%)

Query: 18  KNCGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITFSHPAGLS 77
           +NC AD      +G          L VGS   L   V ++N G+D+Y TT+    P GL 
Sbjct: 625 ENCSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNVSLFNAGDDAYETTLHVKLPVGLY 684

Query: 78  YRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFRGGAQITFLATFDVSPKA 137
           +  + E      L    + C+     + G     C I ++     ++I      DVS  +
Sbjct: 685 FIKILE------LEEKQINCE--VTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLS 736

Query: 138 VLGDRLLLTANVSSEN--NTPRTSKTTFQLELPVKYAVYTVVSSHEQFTKYLNFSESEEK 195
              + L +T + + EN         +   + +P+KY V   V      T ++ +  ++E 
Sbjct: 737 RAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVHGFVNPTSFV-YGSNDEN 795

Query: 196 ESHVAM 201
           E    M
Sbjct: 796 EPETCM 801



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 19/38 (50%), Positives = 29/38 (76%)

Query: 407  LIVGSSIGGLLLLALITAVLYKVGFFKRQYKEMMEEAN 444
            +I  S + GL++L LI+ V++K GFFKRQYK +++E N
Sbjct: 980  IISSSLLLGLIVLLLISYVMWKAGFFKRQYKSILQEEN 1017


>gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]
          Length = 1044

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 116/469 (24%), Positives = 177/469 (37%), Gaps = 86/469 (18%)

Query: 17  EKNCGADHICQDNLGI-----------------SFSFPGLKSLLVGSNLE-LNAEVMVWN 58
           ++ CG D ICQ NL +                      G  +L   S    +  E+MV N
Sbjct: 541 KQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTN 600

Query: 59  ----------DGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTW 108
                     DG+D++   +    P  L Y  V         R+L        + ++   
Sbjct: 601 LPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGV---------RALDPAEKPLCLSNENAS 651

Query: 109 STSCRINHLIFRGGAQITF---LATFDVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQL 165
              C + + + RG AQ+TF   L+T  +S +    +  LL A +S +   P +++    +
Sbjct: 652 HVECELGNPMKRG-AQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFI 710

Query: 166 ELPVKYAVYTVVSSHEQFTKYLNFSESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQ--R 223
           ELP+  A   +        + L FS     E   AM   +  G        V+N GQ  R
Sbjct: 711 ELPLSIAGMAI-------PQQLFFSGVVRGER--AMQSERDVGSKVKYEVTVSNQGQSLR 761

Query: 224 DLPVS-INFWVPVELNQEAVW----MDVEVSHPQVPKD---CMWLLHECPFYLDSLCPMW 275
            L  + +N   P E+     W    M VE+   Q P     C    +     +DS     
Sbjct: 762 TLGSAFLNIMWPHEI-ANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRR 820

Query: 276 VPDVPAETLVLCIFPQNPSLRCSSEKIAPPASDFLAHIQKNPVLDCS--IAGCLRFRCDV 333
               P E        Q P  R        P S   A  +KN  LDC+   A C+ F C  
Sbjct: 821 RELEPPEQ-------QEPGERQEPSMSWWPVSS--AEKKKNITLDCARGTANCVVFSC-- 869

Query: 334 PSFSVQEELDFTLKGNLSFGWVRQILQ-----KKVSVVSVAEITFDTSVYSQLPGQEAFM 388
           P +S        + G L   W    L+     K + V+  A IT  +S+   L  ++A  
Sbjct: 870 PLYSFDRAAVLHVWGRL---WNSTFLEEYSAVKSLEVIVRANITVKSSI-KNLMLRDAST 925

Query: 389 RAQTTTVLEKYKVHN---PTPLIVGSSIGGLLLLALITAVLYKVGFFKR 434
                  L+   V     P  +I+ + + GLL+LAL+  +L+K+GFFKR
Sbjct: 926 VIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKR 974


>gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]
          Length = 1141

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 116/469 (24%), Positives = 177/469 (37%), Gaps = 86/469 (18%)

Query: 17   EKNCGADHICQDNLGI-----------------SFSFPGLKSLLVGSNLE-LNAEVMVWN 58
            ++ CG D ICQ NL +                      G  +L   S    +  E+MV N
Sbjct: 638  KQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTN 697

Query: 59   ----------DGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTW 108
                      DG+D++   +    P  L Y  V         R+L        + ++   
Sbjct: 698  LPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGV---------RALDPAEKPLCLSNENAS 748

Query: 109  STSCRINHLIFRGGAQITF---LATFDVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQL 165
               C + + + RG AQ+TF   L+T  +S +    +  LL A +S +   P +++    +
Sbjct: 749  HVECELGNPMKRG-AQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFI 807

Query: 166  ELPVKYAVYTVVSSHEQFTKYLNFSESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQ--R 223
            ELP+  A   +        + L FS     E   AM   +  G        V+N GQ  R
Sbjct: 808  ELPLSIAGMAI-------PQQLFFSGVVRGER--AMQSERDVGSKVKYEVTVSNQGQSLR 858

Query: 224  DLPVS-INFWVPVELNQEAVW----MDVEVSHPQVPKD---CMWLLHECPFYLDSLCPMW 275
             L  + +N   P E+     W    M VE+   Q P     C    +     +DS     
Sbjct: 859  TLGSAFLNIMWPHEI-ANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRR 917

Query: 276  VPDVPAETLVLCIFPQNPSLRCSSEKIAPPASDFLAHIQKNPVLDCS--IAGCLRFRCDV 333
                P E        Q P  R        P S   A  +KN  LDC+   A C+ F C  
Sbjct: 918  RELEPPEQ-------QEPGERQEPSMSWWPVSS--AEKKKNITLDCARGTANCVVFSC-- 966

Query: 334  PSFSVQEELDFTLKGNLSFGWVRQILQ-----KKVSVVSVAEITFDTSVYSQLPGQEAFM 388
            P +S        + G L   W    L+     K + V+  A IT  +S+   L  ++A  
Sbjct: 967  PLYSFDRAAVLHVWGRL---WNSTFLEEYSAVKSLEVIVRANITVKSSI-KNLMLRDAST 1022

Query: 389  RAQTTTVLEKYKVHN---PTPLIVGSSIGGLLLLALITAVLYKVGFFKR 434
                   L+   V     P  +I+ + + GLL+LAL+  +L+K+GFFKR
Sbjct: 1023 VIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKR 1071


>gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]
          Length = 1137

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 116/469 (24%), Positives = 177/469 (37%), Gaps = 86/469 (18%)

Query: 17   EKNCGADHICQDNLGI-----------------SFSFPGLKSLLVGSNLE-LNAEVMVWN 58
            ++ CG D ICQ NL +                      G  +L   S    +  E+MV N
Sbjct: 634  KQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTN 693

Query: 59   ----------DGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTW 108
                      DG+D++   +    P  L Y  V         R+L        + ++   
Sbjct: 694  LPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGV---------RALDPAEKPLCLSNENAS 744

Query: 109  STSCRINHLIFRGGAQITF---LATFDVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQL 165
               C + + + RG AQ+TF   L+T  +S +    +  LL A +S +   P +++    +
Sbjct: 745  HVECELGNPMKRG-AQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFI 803

Query: 166  ELPVKYAVYTVVSSHEQFTKYLNFSESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQ--R 223
            ELP+  A   +        + L FS     E   AM   +  G        V+N GQ  R
Sbjct: 804  ELPLSIAGMAI-------PQQLFFSGVVRGER--AMQSERDVGSKVKYEVTVSNQGQSLR 854

Query: 224  DLPVS-INFWVPVELNQEAVW----MDVEVSHPQVPKD---CMWLLHECPFYLDSLCPMW 275
             L  + +N   P E+     W    M VE+   Q P     C    +     +DS     
Sbjct: 855  TLGSAFLNIMWPHEI-ANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRR 913

Query: 276  VPDVPAETLVLCIFPQNPSLRCSSEKIAPPASDFLAHIQKNPVLDCS--IAGCLRFRCDV 333
                P E        Q P  R        P S   A  +KN  LDC+   A C+ F C  
Sbjct: 914  RELEPPEQ-------QEPGERQEPSMSWWPVSS--AEKKKNITLDCARGTANCVVFSC-- 962

Query: 334  PSFSVQEELDFTLKGNLSFGWVRQILQ-----KKVSVVSVAEITFDTSVYSQLPGQEAFM 388
            P +S        + G L   W    L+     K + V+  A IT  +S+   L  ++A  
Sbjct: 963  PLYSFDRAAVLHVWGRL---WNSTFLEEYSAVKSLEVIVRANITVKSSI-KNLMLRDAST 1018

Query: 389  RAQTTTVLEKYKVHN---PTPLIVGSSIGGLLLLALITAVLYKVGFFKR 434
                   L+   V     P  +I+ + + GLL+LAL+  +L+K+GFFKR
Sbjct: 1019 VIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKR 1067


>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
          Length = 1167

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 43/187 (22%), Positives = 80/187 (42%), Gaps = 31/187 (16%)

Query: 14  LPFEKNCGADHICQDNLGISFSFP-------------GLKSLLVGSNLELNAEVMVWNDG 60
           +PF K+CG D+ C  +L +  +               G + +LV + LE        N  
Sbjct: 783 VPFSKDCGPDNECVTDLVLQVNMDIRGSRKAPFVVRGGRRKVLVSTTLE--------NRK 834

Query: 61  EDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFR 120
           E++Y T+++      L    +   Q++  ++   + C +AP       +  C + H +F+
Sbjct: 835 ENAYNTSLSLIFSRNLHLASLTP-QRESPIK---VEC-AAP----SAHARLCSVGHPVFQ 885

Query: 121 GGAQITFLATFDVSPKAVLGDRLL-LTANVSSENNTPRTSKTTFQLELPVKYAVYTVVSS 179
            GA++TFL  F+ S  ++L    + LTA+  S          T Q    ++Y  + + SS
Sbjct: 886 TGAKVTFLLEFEFSCSSLLSQVFVKLTASSDSLERNGTLQDNTAQTSAYIQYEPHLLFSS 945

Query: 180 HEQFTKY 186
                +Y
Sbjct: 946 ESTLHRY 952



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 35/130 (26%), Positives = 62/130 (47%), Gaps = 3/130 (2%)

Query: 313  IQKNPVLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKKVSVVSVAEIT 372
            +Q    L+ S   C   RC +   +   E+   L   +   + R+   K ++VVS  E+ 
Sbjct: 1032 LQHTNRLNGSNTQCQVVRCHLGQLAKGTEVSVGLLRLVHNEFFRRAKFKSLTVVSTFELG 1091

Query: 373  FDTSVYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVGSSIGGLLLLALITAVLYKVGFF 432
             +     QL     +  +    V++   +     +++GS +GGLLLLAL+   L+K+GFF
Sbjct: 1092 TEEGSVLQLTEASRWSES-LLEVVQTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFF 1150

Query: 433  KRQYKEMMEE 442
               +K++ EE
Sbjct: 1151 --AHKKIPEE 1158


>gi|49170034 integrin, alpha 8 [Homo sapiens]
          Length = 1063

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 34/124 (27%), Positives = 59/124 (47%), Gaps = 10/124 (8%)

Query: 318  VLDCSIAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKKVSVVSVAE-ITFDTS 376
            +L+C+   CL+  C V      E     ++  L   W    LQ+K    ++A  ++F+  
Sbjct: 921  ILNCTNIECLQISCAVGRLEGGESAVLKVRSRL---WAHTFLQRKNDPYALASLVSFEVK 977

Query: 377  V--YSQLPGQ--EAFMRAQTTTVLEKYKVHNPTPL--IVGSSIGGLLLLALITAVLYKVG 430
               Y+  P +  E  +  +T+ +     V    PL  I+ + + GLL+LA++T  L+K G
Sbjct: 978  KMPYTDQPAKLPEGSIAIKTSVIWATPNVSFSIPLWVIILAILLGLLVLAILTLALWKCG 1037

Query: 431  FFKR 434
            FF R
Sbjct: 1038 FFDR 1041


>gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [Homo
            sapiens]
          Length = 1091

 Score = 39.3 bits (90), Expect = 0.008
 Identities = 103/471 (21%), Positives = 181/471 (38%), Gaps = 102/471 (21%)

Query: 17   EKNCGADHICQDNLGISFSF----------------PGLKSLLVGSNLELNAEVMVWN-- 58
            ++ CG D++C  NL + + F                 G+  L++    ++  E+ V N  
Sbjct: 623  KEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSP 682

Query: 59   --------DGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSL---HLTCDSAPVGSQGT 107
                    DG+D++   +  + P  L+Y    E      LR+     L+C +   GSQ  
Sbjct: 683  SNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRE------LRAFPEKQLSCVANQNGSQ-- 734

Query: 108  WSTSCRINHLIFRGGAQITFL-------ATFDVSPKAVLGDRLLLTANVSSENNTPRTSK 160
                C + +  F+  + +TF         TFD +P   +  +L  T+N   +N  P T+K
Sbjct: 735  --ADCELGN-PFKRNSNVTFYLVLSTTEVTFD-TPDLDINLKLETTSN--QDNLAPITAK 788

Query: 161  TTFQLELPVKYAVYTVVSSHEQFTKYLNFSESEEKESHVAMHRYQAGGGDAGDWA----- 215
                +EL +  +                      K S V       GG   G+ A     
Sbjct: 789  AKVVIELLLSVS-------------------GVAKPSQVYF-----GGTVVGEQAMKSED 824

Query: 216  GVNNLGQRDLPVSINFWVPVELNQEAVWMDVEVSHPQVPKDCMWLLHECPFYLDSLCPMW 275
             V +L + +  V IN   P+     A    + +  P+   +  WLL+        L  + 
Sbjct: 825  EVGSLIEYEFRV-INLGKPLTNLGTAT---LNIQWPKEISNGKWLLYLVKVESKGLEKVT 880

Query: 276  V-PDVPAETLVLCIFPQNPSLRCSSEKIAPPASDFLAHIQKN-PVLDCSI-AGCLRFRCD 332
              P     +L L     +   R  +EK       F    ++    L+CS+   C+  RC 
Sbjct: 881  CEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNIRC- 939

Query: 333  VPSFSVQEELDFTLKGNLSFGWVRQILQK--KVSVVSVAEITF-DTSVYSQ---LPGQEA 386
             P   +  +    L+  L   W    L++  K++ + +    F D +  ++   LP    
Sbjct: 940  -PLRGLDSKASLILRSRL---WNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGT 995

Query: 387  FMRA---QTTTVLEKYKVHNPTPLIVGSSIGGLLLLALITAVLYKVGFFKR 434
             +R     + TV +   V  P  +I+ + + G+L+LAL+  +L+K GFFKR
Sbjct: 996  QVRVTVFPSKTVAQYSGV--PWWIILVAILAGILMLALLVFILWKCGFFKR 1044


>gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [Homo
            sapiens]
          Length = 1073

 Score = 38.5 bits (88), Expect = 0.013
 Identities = 105/478 (21%), Positives = 184/478 (38%), Gaps = 108/478 (22%)

Query: 17   EKNCGADHICQDNLGISFSF----------------PGLKSLLVGSNLELNAEVMVWN-- 58
            ++ CG D++C  NL + + F                 G+  L++    ++  E+ V N  
Sbjct: 623  KEGCGDDNVCNSNLKLEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSP 682

Query: 59   --------DGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSL---HLTCDSAPVGSQGT 107
                    DG+D++   +  + P  L+Y    E      LR+     L+C +   GSQ  
Sbjct: 683  SNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRE------LRAFPEKQLSCVANQNGSQA- 735

Query: 108  WSTSCRINHLIFRGGAQITFL-------ATFDVSPKAVLGDRLLLTANVSSENNTPRTSK 160
                C + +  F+  + +TF         TFD +P   +  +L  T+N  +       +K
Sbjct: 736  ---DCELGNP-FKRNSNVTFYLVLSTTEVTFD-TPDLDINLKLETTSNQDNLAPITAKAK 790

Query: 161  TTFQLELPVK--------YAVYTVVSSHEQFTKYLNFSESEEKESHVAMHRYQAGGGDAG 212
               +L L V         Y   TVV   EQ  K      SE++   +  + ++       
Sbjct: 791  VVIELLLSVSGVAKPSQVYFGGTVVG--EQAMK------SEDEVGSLIEYEFR------- 835

Query: 213  DWAGVNNLGQRDLPVSINFWVPVELNQEAVWMDVEVSHPQVPKDCMWLLHECPFYLDSLC 272
                V NLG+           P+     A    + +  P+   +  WLL+        L 
Sbjct: 836  ----VINLGK-----------PLTNLGTAT---LNIQWPKEISNGKWLLYLVKVESKGLE 877

Query: 273  PMWV-PDVPAETLVLCIFPQNPSLRCSSEKIAPPASDF-LAHIQKNPVLDCSI-AGCLRF 329
             +   P     +L L     +   R  +EK       F L   +K   L+CS+   C+  
Sbjct: 878  KVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERKYQTLNCSVNVNCVNI 937

Query: 330  RCDVPSFSVQEELDFTLKGNLSFGWVRQILQK--KVSVVSVAEITF-DTSVYSQ---LPG 383
            RC  P   +  +    L+  L   W    L++  K++ + +    F D +  ++   LP 
Sbjct: 938  RC--PLRGLDSKASLILRSRL---WNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPN 992

Query: 384  QEAFMRAQ---TTTVLEKYKVHNPTPLIVGSSIGGLLLLALITAVLYKVGFFKRQYKE 438
                +R     + TV +   V  P  +I+ + + G+L+LAL+  +L+K GFFKR  K+
Sbjct: 993  AGTQVRVTVFPSKTVAQYSGV--PWWIILVAILAGILMLALLVFILWKCGFFKRNKKD 1048


>gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]
          Length = 1051

 Score = 34.7 bits (78), Expect = 0.19
 Identities = 22/47 (46%), Positives = 26/47 (55%), Gaps = 5/47 (10%)

Query: 415  GLLLLALITAVLYKVGFFKRQYKEMMEEANGQIAPENGTQTPSPPSE 461
            GLLLL LI  +L+K GFFKR     + EA  Q A     +  S PSE
Sbjct: 1002 GLLLLGLIILLLWKCGFFKRARTRALYEAKRQKA-----EMKSQPSE 1043


>gi|38016947 complement component 5 preproprotein [Homo sapiens]
          Length = 1676

 Score = 32.7 bits (73), Expect = 0.71
 Identities = 25/93 (26%), Positives = 38/93 (40%), Gaps = 3/93 (3%)

Query: 101  PVGSQGTWSTSCRINHLIFRGGAQITFLATFDVSPKAVLGDRLLLTANVSSENNTPRTSK 160
            P+  QGT     R N L       I     FD+ P   +   L+   N   EN  P  ++
Sbjct: 1126 PIKLQGTLPVEARENSLYLTAFTVIGIRKAFDICPLVKIDTALIKADNFLLENTLP--AQ 1183

Query: 161  TTFQLELPVKYAVYTVVSSHEQFTKYLNFSESE 193
            +TF L +   YA+     +H QF   ++  + E
Sbjct: 1184 STFTLAISA-YALSLGDKTHPQFRSIVSALKRE 1215


>gi|110227857 thiamin pyrophosphokinase 1 isoform b [Homo sapiens]
          Length = 194

 Score = 30.0 bits (66), Expect = 4.6
 Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 1/57 (1%)

Query: 173 VYTVVSSHEQFTKYLNFSESEEKESHV-AMHRYQAGGGDAGDWAGVNNLGQRDLPVS 228
           + T    H  FTK L   + + +E  +   HR     G  GDW G+  +GQ  + V+
Sbjct: 91  ISTPDQDHTDFTKCLKMLQKKIEEKDLKGKHRLHVDTGMEGDWCGLIPVGQPCMQVT 147


>gi|110815802 hypothetical protein LOC84267 [Homo sapiens]
          Length = 341

 Score = 29.3 bits (64), Expect = 7.9
 Identities = 25/76 (32%), Positives = 38/76 (50%), Gaps = 7/76 (9%)

Query: 184 TKYLNFSESEEKESHVAMHRYQAGGGDAGDW---AGVNNLGQRDLPV-SINFWVPVELNQ 239
           T  LNFS   E++ H  + RY+ G   +G W   A VN      +P+ S +++  V L+Q
Sbjct: 71  TDTLNFSFWSEQDEHKCVVRYR-GKTYSGYWSLCAAVNRALDEGIPITSASYYATVTLDQ 129

Query: 240 --EAVWMDVEVSHPQV 253
               +  D +VS P V
Sbjct: 130 VRNILRSDTDVSMPLV 145


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,612,819
Number of Sequences: 37866
Number of extensions: 825619
Number of successful extensions: 1988
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1913
Number of HSP's gapped (non-prelim): 58
length of query: 462
length of database: 18,247,518
effective HSP length: 106
effective length of query: 356
effective length of database: 14,233,722
effective search space: 5067205032
effective search space used: 5067205032
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press