Guide to the Human Genome
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Search of human proteins with 239751049

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239751049 PREDICTED: similar to ATPase, Ca++ transporting,
fast twitch 1 [Homo sapiens]
         (879 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239751049 PREDICTED: similar to ATPase, Ca++ transporting, fa...  1784   0.0  
gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [...  1157   0.0  
gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [...  1157   0.0  
gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H...   996   0.0  
gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [...   996   0.0  
gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 ...   936   0.0  
gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom...   911   0.0  
gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom...   911   0.0  
gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom...   911   0.0  
gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom...   911   0.0  
gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom...   911   0.0  
gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom...   911   0.0  
gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom...   911   0.0  
gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap...   246   9e-65
gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap...   246   9e-65
gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap...   246   9e-65
gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap...   246   9e-65
gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ...   239   8e-63
gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]   184   3e-46
gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]             183   5e-46
gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi...   181   3e-45
gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi...   181   3e-45
gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]   181   3e-45
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi...   177   3e-44
gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]    175   1e-43
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]   157   4e-38
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap...   153   6e-37
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa...   142   1e-33
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa...   142   1e-33
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa...   141   2e-33

>gi|239751049 PREDICTED: similar to ATPase, Ca++ transporting, fast
           twitch 1 [Homo sapiens]
          Length = 879

 Score = 1784 bits (4620), Expect = 0.0
 Identities = 879/879 (100%), Positives = 879/879 (100%)

Query: 1   MAMAIVCCGDWGQLGWEGSPLSAHRPEGWPRPVPIILQCCAFGAIPVSDSLVRGALNDAL 60
           MAMAIVCCGDWGQLGWEGSPLSAHRPEGWPRPVPIILQCCAFGAIPVSDSLVRGALNDAL
Sbjct: 1   MAMAIVCCGDWGQLGWEGSPLSAHRPEGWPRPVPIILQCCAFGAIPVSDSLVRGALNDAL 60

Query: 61  GVSCEFLSWDSSRLPRSCPSLRLPLSMFGHSHCCKTVAPVTPPGAGGETPASAKSLGGCE 120
           GVSCEFLSWDSSRLPRSCPSLRLPLSMFGHSHCCKTVAPVTPPGAGGETPASAKSLGGCE
Sbjct: 61  GVSCEFLSWDSSRLPRSCPSLRLPLSMFGHSHCCKTVAPVTPPGAGGETPASAKSLGGCE 120

Query: 121 PESSGDGLDICPYFPQTCPQKSTLPHSFGLEPLLGPASPGPDTFLSHSLPLAPKRCSPFI 180
           PESSGDGLDICPYFPQTCPQKSTLPHSFGLEPLLGPASPGPDTFLSHSLPLAPKRCSPFI
Sbjct: 121 PESSGDGLDICPYFPQTCPQKSTLPHSFGLEPLLGPASPGPDTFLSHSLPLAPKRCSPFI 180

Query: 181 SPPKAWGPAGGRGVAGCSSGTGVRALWREEKPGGGRRVKRRNPGRQAVGHTEEDPPRVGT 240
           SPPKAWGPAGGRGVAGCSSGTGVRALWREEKPGGGRRVKRRNPGRQAVGHTEEDPPRVGT
Sbjct: 181 SPPKAWGPAGGRGVAGCSSGTGVRALWREEKPGGGRRVKRRNPGRQAVGHTEEDPPRVGT 240

Query: 241 PWKEHTGPGPQEGSTMEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEE 300
           PWKEHTGPGPQEGSTMEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEE
Sbjct: 241 PWKEHTGPGPQEGSTMEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEE 300

Query: 301 GKTLWELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVG 360
           GKTLWELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVG
Sbjct: 301 GKTLWELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVG 360

Query: 361 VWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRI 420
           VWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRI
Sbjct: 361 VWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRI 420

Query: 421 LAIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVAT 480
           LAIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVAT
Sbjct: 421 LAIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVAT 480

Query: 481 TGVGTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHG 540
           TGVGTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHG
Sbjct: 481 TGVGTEIGKIRDQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHG 540

Query: 541 GSWFRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCT 600
           GSWFRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCT
Sbjct: 541 GSWFRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCT 600

Query: 601 SVICSDKTGTLTTNQMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPG 660
           SVICSDKTGTLTTNQMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPG
Sbjct: 601 SVICSDKTGTLTTNQMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPG 660

Query: 661 QYDGLVELATICALCNDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKV 720
           QYDGLVELATICALCNDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKV
Sbjct: 661 QYDGLVELATICALCNDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKV 720

Query: 721 ERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRC 780
           ERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRC
Sbjct: 721 ERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRC 780

Query: 781 NYVRVGTTRVPLTGPVKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFL 840
           NYVRVGTTRVPLTGPVKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFL
Sbjct: 781 NYVRVGTTRVPLTGPVKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFL 840

Query: 841 EYEVSSWEPPTVVELVKGRVPAIHSQLHHPDHFLPRQSS 879
           EYEVSSWEPPTVVELVKGRVPAIHSQLHHPDHFLPRQSS
Sbjct: 841 EYEVSSWEPPTVVELVKGRVPAIHSQLHHPDHFLPRQSS 879


>gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b
           [Homo sapiens]
          Length = 994

 Score = 1157 bits (2993), Expect = 0.0
 Identities = 588/588 (100%), Positives = 588/588 (100%)

Query: 256 MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 315
           MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL
Sbjct: 1   MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 60

Query: 316 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 375
           LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK
Sbjct: 61  LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120

Query: 376 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 435
           EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL
Sbjct: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180

Query: 436 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 495
           TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA
Sbjct: 181 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 240

Query: 496 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 555
           ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV
Sbjct: 241 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 300

Query: 556 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 615
           ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 616 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 675
           MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC
Sbjct: 361 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 420

Query: 676 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 735
           NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK
Sbjct: 421 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 480

Query: 736 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 795
           KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP
Sbjct: 481 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 540

Query: 796 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYE 843
           VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYE
Sbjct: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYE 588


>gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a
           [Homo sapiens]
          Length = 1001

 Score = 1157 bits (2993), Expect = 0.0
 Identities = 588/588 (100%), Positives = 588/588 (100%)

Query: 256 MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 315
           MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL
Sbjct: 1   MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 60

Query: 316 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 375
           LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK
Sbjct: 61  LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120

Query: 376 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 435
           EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL
Sbjct: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180

Query: 436 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 495
           TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA
Sbjct: 181 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 240

Query: 496 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 555
           ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV
Sbjct: 241 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 300

Query: 556 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 615
           ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 616 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 675
           MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC
Sbjct: 361 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 420

Query: 676 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 735
           NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK
Sbjct: 421 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 480

Query: 736 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 795
           KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP
Sbjct: 481 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 540

Query: 796 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYE 843
           VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYE
Sbjct: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYE 588


>gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo
           sapiens]
          Length = 997

 Score =  996 bits (2575), Expect = 0.0
 Identities = 497/590 (84%), Positives = 550/590 (93%), Gaps = 1/590 (0%)

Query: 256 MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 315
           ME AH KT EE L +FGV+E+TGL+ +QVK+  E++G NELPAEEGKTL ELVIEQFEDL
Sbjct: 1   MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60

Query: 316 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 375
           LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLIL+ANAIVGVWQERNAENAIEALK
Sbjct: 61  LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120

Query: 376 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 435
           EYEPEMGKVYR DRKSVQRIKA+DIVPGDIVE+AVGDKVPADIR+ +IKSTTLRVDQSIL
Sbjct: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180

Query: 436 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 495
           TGESVSVIKHT+PVPDPRAVNQDKKNMLFSGTNIAAGKA+G+V  TGV TEIGKIRD+M 
Sbjct: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240

Query: 496 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 555
           ATEQ++TPLQQKLDEFGEQLSKVISLIC+AVW+INIGHFNDPVHGGSW RGAIYYFKIAV
Sbjct: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300

Query: 556 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 615
           ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 616 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 675
           MSVC+MFI+D+V+GD C LNEF+ITGSTYAP GEV K+DKPV   QYDGLVELATICALC
Sbjct: 361 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 420

Query: 676 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 735
           NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+T+++ LSK+ERANACNSVI+QLMK
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 480

Query: 736 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 795
           KEFTLEFSRDRKSMSVYC+P K SR ++ +KMFVKGAPEGVIDRC ++RVG+T+VP+T  
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 539

Query: 796 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYEVS 845
           VK+KIM+VI+EWG+G DTLRCLALAT D P +REEM L+DSA F++YE +
Sbjct: 540 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETN 589


>gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1
           [Homo sapiens]
          Length = 1042

 Score =  996 bits (2575), Expect = 0.0
 Identities = 497/590 (84%), Positives = 550/590 (93%), Gaps = 1/590 (0%)

Query: 256 MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 315
           ME AH KT EE L +FGV+E+TGL+ +QVK+  E++G NELPAEEGKTL ELVIEQFEDL
Sbjct: 1   MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60

Query: 316 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 375
           LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLIL+ANAIVGVWQERNAENAIEALK
Sbjct: 61  LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120

Query: 376 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 435
           EYEPEMGKVYR DRKSVQRIKA+DIVPGDIVE+AVGDKVPADIR+ +IKSTTLRVDQSIL
Sbjct: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180

Query: 436 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 495
           TGESVSVIKHT+PVPDPRAVNQDKKNMLFSGTNIAAGKA+G+V  TGV TEIGKIRD+M 
Sbjct: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240

Query: 496 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 555
           ATEQ++TPLQQKLDEFGEQLSKVISLIC+AVW+INIGHFNDPVHGGSW RGAIYYFKIAV
Sbjct: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300

Query: 556 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 615
           ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 616 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 675
           MSVC+MFI+D+V+GD C LNEF+ITGSTYAP GEV K+DKPV   QYDGLVELATICALC
Sbjct: 361 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 420

Query: 676 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 735
           NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+T+++ LSK+ERANACNSVI+QLMK
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 480

Query: 736 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 795
           KEFTLEFSRDRKSMSVYC+P K SR ++ +KMFVKGAPEGVIDRC ++RVG+T+VP+T  
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 539

Query: 796 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYEVS 845
           VK+KIM+VI+EWG+G DTLRCLALAT D P +REEM L+DSA F++YE +
Sbjct: 540 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETN 589


>gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3
           [Homo sapiens]
          Length = 1015

 Score =  936 bits (2420), Expect = 0.0
 Identities = 473/590 (80%), Positives = 524/590 (88%), Gaps = 28/590 (4%)

Query: 256 MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 315
           ME AH KT EE L +FGV+E+TGL+ +QVK+  E++G NELPAEEGKTL ELVIEQFEDL
Sbjct: 1   MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60

Query: 316 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 375
           LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLIL+ANAIVGVWQERNAENAIEALK
Sbjct: 61  LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120

Query: 376 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 435
           EYEPEMGKVYR DRKSVQRIKA+DIVPGDIVE+A                          
Sbjct: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIA-------------------------- 154

Query: 436 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 495
            GESVSVIKHT+PVPDPRAVNQDKKNMLFSGTNIAAGKA+G+V  TGV TEIGKIRD+M 
Sbjct: 155 -GESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 213

Query: 496 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 555
           ATEQ++TPLQQKLDEFGEQLSKVISLIC+AVW+INIGHFNDPVHGGSW RGAIYYFKIAV
Sbjct: 214 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 273

Query: 556 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 615
           ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 274 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 333

Query: 616 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 675
           MSVC+MFI+D+V+GD C LNEF+ITGSTYAP GEV K+DKPV   QYDGLVELATICALC
Sbjct: 334 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 393

Query: 676 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 735
           NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+T+++ LSK+ERANACNSVI+QLMK
Sbjct: 394 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 453

Query: 736 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 795
           KEFTLEFSRDRKSMSVYC+P K SR ++ +KMFVKGAPEGVIDRC ++RVG+T+VP+T  
Sbjct: 454 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 512

Query: 796 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYEVS 845
           VK+KIM+VI+EWG+G DTLRCLALAT D P +REEM L+DSA F++YE +
Sbjct: 513 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETN 562


>gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo
           sapiens]
          Length = 999

 Score =  911 bits (2355), Expect = 0.0
 Identities = 448/588 (76%), Positives = 518/588 (88%)

Query: 256 MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 315
           MEAAH     + L +F V+   GL+P QV    E+YG NELP+EEGK+LWELV+EQFEDL
Sbjct: 1   MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60

Query: 316 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 375
           LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LIL+ANAIVGVWQERNAE+AIEALK
Sbjct: 61  LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120

Query: 376 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 435
           EYEPEMGKV R+DRK VQRI+ARDIVPGDIVEVAVGDKVPAD+R++ IKSTTLRVDQSIL
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180

Query: 436 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 495
           TGESVSV KHTE +PDPRAVNQDKKNMLFSGTNI +GKA+G+   TG+ TE+GKIR QMA
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240

Query: 496 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 555
           A E ++TPLQ+KLDEFG QLS  IS+ICVAVW+INIGHF DP HGGSW RGA+YYFKIAV
Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300

Query: 556 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 615
           ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 616 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 675
           MSVC+MF++ + D   CLL+EF+I+G+TY PEGEV + D+PVR GQ+DGLVELATICALC
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420

Query: 676 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 735
           NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+TD+++LS+VERA ACN+VI+QLM+
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480

Query: 736 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 795
           KEFTLEFSRDRKSMSVYC+P +      G+KMFVKGAPE VI+RC+ VRVG+   PLT  
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540

Query: 796 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYE 843
            +E+I+A I++WG+G DTLRCLALATRD PP++E+M LDD ++F++YE
Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYE 588


>gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
           sapiens]
          Length = 1029

 Score =  911 bits (2355), Expect = 0.0
 Identities = 448/588 (76%), Positives = 518/588 (88%)

Query: 256 MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 315
           MEAAH     + L +F V+   GL+P QV    E+YG NELP+EEGK+LWELV+EQFEDL
Sbjct: 1   MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60

Query: 316 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 375
           LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LIL+ANAIVGVWQERNAE+AIEALK
Sbjct: 61  LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120

Query: 376 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 435
           EYEPEMGKV R+DRK VQRI+ARDIVPGDIVEVAVGDKVPAD+R++ IKSTTLRVDQSIL
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180

Query: 436 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 495
           TGESVSV KHTE +PDPRAVNQDKKNMLFSGTNI +GKA+G+   TG+ TE+GKIR QMA
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240

Query: 496 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 555
           A E ++TPLQ+KLDEFG QLS  IS+ICVAVW+INIGHF DP HGGSW RGA+YYFKIAV
Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300

Query: 556 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 615
           ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 616 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 675
           MSVC+MF++ + D   CLL+EF+I+G+TY PEGEV + D+PVR GQ+DGLVELATICALC
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420

Query: 676 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 735
           NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+TD+++LS+VERA ACN+VI+QLM+
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480

Query: 736 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 795
           KEFTLEFSRDRKSMSVYC+P +      G+KMFVKGAPE VI+RC+ VRVG+   PLT  
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540

Query: 796 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYE 843
            +E+I+A I++WG+G DTLRCLALATRD PP++E+M LDD ++F++YE
Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYE 588


>gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo
           sapiens]
          Length = 998

 Score =  911 bits (2355), Expect = 0.0
 Identities = 448/588 (76%), Positives = 518/588 (88%)

Query: 256 MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 315
           MEAAH     + L +F V+   GL+P QV    E+YG NELP+EEGK+LWELV+EQFEDL
Sbjct: 1   MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60

Query: 316 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 375
           LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LIL+ANAIVGVWQERNAE+AIEALK
Sbjct: 61  LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120

Query: 376 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 435
           EYEPEMGKV R+DRK VQRI+ARDIVPGDIVEVAVGDKVPAD+R++ IKSTTLRVDQSIL
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180

Query: 436 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 495
           TGESVSV KHTE +PDPRAVNQDKKNMLFSGTNI +GKA+G+   TG+ TE+GKIR QMA
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240

Query: 496 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 555
           A E ++TPLQ+KLDEFG QLS  IS+ICVAVW+INIGHF DP HGGSW RGA+YYFKIAV
Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300

Query: 556 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 615
           ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 616 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 675
           MSVC+MF++ + D   CLL+EF+I+G+TY PEGEV + D+PVR GQ+DGLVELATICALC
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420

Query: 676 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 735
           NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+TD+++LS+VERA ACN+VI+QLM+
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480

Query: 736 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 795
           KEFTLEFSRDRKSMSVYC+P +      G+KMFVKGAPE VI+RC+ VRVG+   PLT  
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540

Query: 796 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYE 843
            +E+I+A I++WG+G DTLRCLALATRD PP++E+M LDD ++F++YE
Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYE 588


>gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
           sapiens]
          Length = 1029

 Score =  911 bits (2355), Expect = 0.0
 Identities = 448/588 (76%), Positives = 518/588 (88%)

Query: 256 MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 315
           MEAAH     + L +F V+   GL+P QV    E+YG NELP+EEGK+LWELV+EQFEDL
Sbjct: 1   MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60

Query: 316 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 375
           LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LIL+ANAIVGVWQERNAE+AIEALK
Sbjct: 61  LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120

Query: 376 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 435
           EYEPEMGKV R+DRK VQRI+ARDIVPGDIVEVAVGDKVPAD+R++ IKSTTLRVDQSIL
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180

Query: 436 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 495
           TGESVSV KHTE +PDPRAVNQDKKNMLFSGTNI +GKA+G+   TG+ TE+GKIR QMA
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240

Query: 496 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 555
           A E ++TPLQ+KLDEFG QLS  IS+ICVAVW+INIGHF DP HGGSW RGA+YYFKIAV
Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300

Query: 556 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 615
           ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 616 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 675
           MSVC+MF++ + D   CLL+EF+I+G+TY PEGEV + D+PVR GQ+DGLVELATICALC
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420

Query: 676 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 735
           NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+TD+++LS+VERA ACN+VI+QLM+
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480

Query: 736 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 795
           KEFTLEFSRDRKSMSVYC+P +      G+KMFVKGAPE VI+RC+ VRVG+   PLT  
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540

Query: 796 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYE 843
            +E+I+A I++WG+G DTLRCLALATRD PP++E+M LDD ++F++YE
Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYE 588


>gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo
           sapiens]
          Length = 1043

 Score =  911 bits (2355), Expect = 0.0
 Identities = 448/588 (76%), Positives = 518/588 (88%)

Query: 256 MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 315
           MEAAH     + L +F V+   GL+P QV    E+YG NELP+EEGK+LWELV+EQFEDL
Sbjct: 1   MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60

Query: 316 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 375
           LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LIL+ANAIVGVWQERNAE+AIEALK
Sbjct: 61  LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120

Query: 376 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 435
           EYEPEMGKV R+DRK VQRI+ARDIVPGDIVEVAVGDKVPAD+R++ IKSTTLRVDQSIL
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180

Query: 436 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 495
           TGESVSV KHTE +PDPRAVNQDKKNMLFSGTNI +GKA+G+   TG+ TE+GKIR QMA
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240

Query: 496 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 555
           A E ++TPLQ+KLDEFG QLS  IS+ICVAVW+INIGHF DP HGGSW RGA+YYFKIAV
Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300

Query: 556 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 615
           ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 616 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 675
           MSVC+MF++ + D   CLL+EF+I+G+TY PEGEV + D+PVR GQ+DGLVELATICALC
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420

Query: 676 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 735
           NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+TD+++LS+VERA ACN+VI+QLM+
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480

Query: 736 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 795
           KEFTLEFSRDRKSMSVYC+P +      G+KMFVKGAPE VI+RC+ VRVG+   PLT  
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540

Query: 796 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYE 843
            +E+I+A I++WG+G DTLRCLALATRD PP++E+M LDD ++F++YE
Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYE 588


>gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo
           sapiens]
          Length = 1044

 Score =  911 bits (2355), Expect = 0.0
 Identities = 448/588 (76%), Positives = 518/588 (88%)

Query: 256 MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 315
           MEAAH     + L +F V+   GL+P QV    E+YG NELP+EEGK+LWELV+EQFEDL
Sbjct: 1   MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60

Query: 316 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 375
           LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LIL+ANAIVGVWQERNAE+AIEALK
Sbjct: 61  LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120

Query: 376 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 435
           EYEPEMGKV R+DRK VQRI+ARDIVPGDIVEVAVGDKVPAD+R++ IKSTTLRVDQSIL
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180

Query: 436 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 495
           TGESVSV KHTE +PDPRAVNQDKKNMLFSGTNI +GKA+G+   TG+ TE+GKIR QMA
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240

Query: 496 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 555
           A E ++TPLQ+KLDEFG QLS  IS+ICVAVW+INIGHF DP HGGSW RGA+YYFKIAV
Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300

Query: 556 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 615
           ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 616 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 675
           MSVC+MF++ + D   CLL+EF+I+G+TY PEGEV + D+PVR GQ+DGLVELATICALC
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420

Query: 676 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 735
           NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+TD+++LS+VERA ACN+VI+QLM+
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480

Query: 736 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 795
           KEFTLEFSRDRKSMSVYC+P +      G+KMFVKGAPE VI+RC+ VRVG+   PLT  
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540

Query: 796 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYE 843
            +E+I+A I++WG+G DTLRCLALATRD PP++E+M LDD ++F++YE
Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYE 588


>gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo
           sapiens]
          Length = 1052

 Score =  911 bits (2355), Expect = 0.0
 Identities = 448/588 (76%), Positives = 518/588 (88%)

Query: 256 MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 315
           MEAAH     + L +F V+   GL+P QV    E+YG NELP+EEGK+LWELV+EQFEDL
Sbjct: 1   MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60

Query: 316 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 375
           LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LIL+ANAIVGVWQERNAE+AIEALK
Sbjct: 61  LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120

Query: 376 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 435
           EYEPEMGKV R+DRK VQRI+ARDIVPGDIVEVAVGDKVPAD+R++ IKSTTLRVDQSIL
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180

Query: 436 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 495
           TGESVSV KHTE +PDPRAVNQDKKNMLFSGTNI +GKA+G+   TG+ TE+GKIR QMA
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240

Query: 496 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 555
           A E ++TPLQ+KLDEFG QLS  IS+ICVAVW+INIGHF DP HGGSW RGA+YYFKIAV
Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300

Query: 556 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 615
           ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 616 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 675
           MSVC+MF++ + D   CLL+EF+I+G+TY PEGEV + D+PVR GQ+DGLVELATICALC
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420

Query: 676 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 735
           NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+TD+++LS+VERA ACN+VI+QLM+
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480

Query: 736 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 795
           KEFTLEFSRDRKSMSVYC+P +      G+KMFVKGAPE VI+RC+ VRVG+   PLT  
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540

Query: 796 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYE 843
            +E+I+A I++WG+G DTLRCLALATRD PP++E+M LDD ++F++YE
Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYE 588


>gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo
           sapiens]
          Length = 939

 Score =  246 bits (627), Expect = 9e-65
 Identities = 191/553 (34%), Positives = 276/553 (49%), Gaps = 77/553 (13%)

Query: 278 GLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWFEEGE 337
           GL   +V      +G NE    E + LW+  I QF++ L+ +LL +A IS ++  F++  
Sbjct: 45  GLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDA- 103

Query: 338 ETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKA 397
                 V   V +LI++  A V   QE  +E ++E L +  P      R  +  ++   A
Sbjct: 104 ------VSITVAILIVVTVAFV---QEYRSEKSLEELSKLVPPECHCVREGK--LEHTLA 152

Query: 398 RDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQ 457
           RD+VPGD V ++VGD+VPAD+R+   ++  L +D+S LTGE+    K T   P P A N 
Sbjct: 153 RDLVPGDTVCLSVGDRVPADLRLF--EAVDLSIDESSLTGETTPCSKVT--APQPAATNG 208

Query: 458 D---KKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAATEQDKTPLQQKLDEFGEQ 514
           D   + N+ F GT +  GKA G+V  TG  +E G++   M A E  KTPLQ+ +D  G+Q
Sbjct: 209 DLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQ 268

Query: 515 LS----KVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVALAVAAIPEGLPAVI 570
           LS     +I +I +  WL+               +  +  F I+V+LAVAAIPEGLP V+
Sbjct: 269 LSFYSFGIIGIIMLVGWLLG--------------KDILEMFTISVSLAVAAIPEGLPIVV 314

Query: 571 TTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGD 630
           T  LALG  RM KK AIV+ LP VETLGC +VICSDKTGTLT N+M+V  +F  D +  +
Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374

Query: 631 ICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCNDSSLDFNEAKGVYE 690
                   +TG  Y   GEV+ +   V       +  +     +CND+ +  N       
Sbjct: 375 --------VTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTL----- 421

Query: 691 KVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMS 750
            +G+ TE AL  L  KM +       + K E                    FS ++K M+
Sbjct: 422 -MGKPTEGALIALAMKMGLDGLQQDYIRKAE------------------YPFSSEQKWMA 462

Query: 751 VYC-SPAKSSRAAVGNKMFVKGAPEGVIDRC-NYVRVGTTRVPLTGPVKEKIMAVIKEWG 808
           V C    +  R  +    F+KGA E VI  C  Y   G T   LT   +++ +   ++  
Sbjct: 463 VKCVHRTQQDRPEI---CFMKGAYEQVIKYCTTYQSKGQT---LTLTQQQRDVYQQEKAR 516

Query: 809 TGRDTLRCLALAT 821
            G   LR LALA+
Sbjct: 517 MGSAGLRVLALAS 529


>gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo
           sapiens]
          Length = 949

 Score =  246 bits (627), Expect = 9e-65
 Identities = 191/553 (34%), Positives = 276/553 (49%), Gaps = 77/553 (13%)

Query: 278 GLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWFEEGE 337
           GL   +V      +G NE    E + LW+  I QF++ L+ +LL +A IS ++  F++  
Sbjct: 45  GLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDA- 103

Query: 338 ETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKA 397
                 V   V +LI++  A V   QE  +E ++E L +  P      R  +  ++   A
Sbjct: 104 ------VSITVAILIVVTVAFV---QEYRSEKSLEELSKLVPPECHCVREGK--LEHTLA 152

Query: 398 RDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQ 457
           RD+VPGD V ++VGD+VPAD+R+   ++  L +D+S LTGE+    K T   P P A N 
Sbjct: 153 RDLVPGDTVCLSVGDRVPADLRLF--EAVDLSIDESSLTGETTPCSKVT--APQPAATNG 208

Query: 458 D---KKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAATEQDKTPLQQKLDEFGEQ 514
           D   + N+ F GT +  GKA G+V  TG  +E G++   M A E  KTPLQ+ +D  G+Q
Sbjct: 209 DLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQ 268

Query: 515 LS----KVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVALAVAAIPEGLPAVI 570
           LS     +I +I +  WL+               +  +  F I+V+LAVAAIPEGLP V+
Sbjct: 269 LSFYSFGIIGIIMLVGWLLG--------------KDILEMFTISVSLAVAAIPEGLPIVV 314

Query: 571 TTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGD 630
           T  LALG  RM KK AIV+ LP VETLGC +VICSDKTGTLT N+M+V  +F  D +  +
Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374

Query: 631 ICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCNDSSLDFNEAKGVYE 690
                   +TG  Y   GEV+ +   V       +  +     +CND+ +  N       
Sbjct: 375 --------VTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTL----- 421

Query: 691 KVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMS 750
            +G+ TE AL  L  KM +       + K E                    FS ++K M+
Sbjct: 422 -MGKPTEGALIALAMKMGLDGLQQDYIRKAE------------------YPFSSEQKWMA 462

Query: 751 VYC-SPAKSSRAAVGNKMFVKGAPEGVIDRC-NYVRVGTTRVPLTGPVKEKIMAVIKEWG 808
           V C    +  R  +    F+KGA E VI  C  Y   G T   LT   +++ +   ++  
Sbjct: 463 VKCVHRTQQDRPEI---CFMKGAYEQVIKYCTTYQSKGQT---LTLTQQQRDVYQQEKAR 516

Query: 809 TGRDTLRCLALAT 821
            G   LR LALA+
Sbjct: 517 MGSAGLRVLALAS 529


>gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo
           sapiens]
          Length = 888

 Score =  246 bits (627), Expect = 9e-65
 Identities = 191/553 (34%), Positives = 276/553 (49%), Gaps = 77/553 (13%)

Query: 278 GLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWFEEGE 337
           GL   +V      +G NE    E + LW+  I QF++ L+ +LL +A IS ++  F++  
Sbjct: 45  GLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDA- 103

Query: 338 ETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKA 397
                 V   V +LI++  A V   QE  +E ++E L +  P      R  +  ++   A
Sbjct: 104 ------VSITVAILIVVTVAFV---QEYRSEKSLEELSKLVPPECHCVREGK--LEHTLA 152

Query: 398 RDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQ 457
           RD+VPGD V ++VGD+VPAD+R+   ++  L +D+S LTGE+    K T   P P A N 
Sbjct: 153 RDLVPGDTVCLSVGDRVPADLRLF--EAVDLSIDESSLTGETTPCSKVT--APQPAATNG 208

Query: 458 D---KKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAATEQDKTPLQQKLDEFGEQ 514
           D   + N+ F GT +  GKA G+V  TG  +E G++   M A E  KTPLQ+ +D  G+Q
Sbjct: 209 DLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQ 268

Query: 515 LS----KVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVALAVAAIPEGLPAVI 570
           LS     +I +I +  WL+               +  +  F I+V+LAVAAIPEGLP V+
Sbjct: 269 LSFYSFGIIGIIMLVGWLLG--------------KDILEMFTISVSLAVAAIPEGLPIVV 314

Query: 571 TTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGD 630
           T  LALG  RM KK AIV+ LP VETLGC +VICSDKTGTLT N+M+V  +F  D +  +
Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374

Query: 631 ICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCNDSSLDFNEAKGVYE 690
                   +TG  Y   GEV+ +   V       +  +     +CND+ +  N       
Sbjct: 375 --------VTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTL----- 421

Query: 691 KVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMS 750
            +G+ TE AL  L  KM +       + K E                    FS ++K M+
Sbjct: 422 -MGKPTEGALIALAMKMGLDGLQQDYIRKAE------------------YPFSSEQKWMA 462

Query: 751 VYC-SPAKSSRAAVGNKMFVKGAPEGVIDRC-NYVRVGTTRVPLTGPVKEKIMAVIKEWG 808
           V C    +  R  +    F+KGA E VI  C  Y   G T   LT   +++ +   ++  
Sbjct: 463 VKCVHRTQQDRPEI---CFMKGAYEQVIKYCTTYQSKGQT---LTLTQQQRDVYQQEKAR 516

Query: 809 TGRDTLRCLALAT 821
            G   LR LALA+
Sbjct: 517 MGSAGLRVLALAS 529


>gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo
           sapiens]
          Length = 919

 Score =  246 bits (627), Expect = 9e-65
 Identities = 191/553 (34%), Positives = 276/553 (49%), Gaps = 77/553 (13%)

Query: 278 GLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWFEEGE 337
           GL   +V      +G NE    E + LW+  I QF++ L+ +LL +A IS ++  F++  
Sbjct: 45  GLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDA- 103

Query: 338 ETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKA 397
                 V   V +LI++  A V   QE  +E ++E L +  P      R  +  ++   A
Sbjct: 104 ------VSITVAILIVVTVAFV---QEYRSEKSLEELSKLVPPECHCVREGK--LEHTLA 152

Query: 398 RDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQ 457
           RD+VPGD V ++VGD+VPAD+R+   ++  L +D+S LTGE+    K T   P P A N 
Sbjct: 153 RDLVPGDTVCLSVGDRVPADLRLF--EAVDLSIDESSLTGETTPCSKVT--APQPAATNG 208

Query: 458 D---KKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAATEQDKTPLQQKLDEFGEQ 514
           D   + N+ F GT +  GKA G+V  TG  +E G++   M A E  KTPLQ+ +D  G+Q
Sbjct: 209 DLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQ 268

Query: 515 LS----KVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVALAVAAIPEGLPAVI 570
           LS     +I +I +  WL+               +  +  F I+V+LAVAAIPEGLP V+
Sbjct: 269 LSFYSFGIIGIIMLVGWLLG--------------KDILEMFTISVSLAVAAIPEGLPIVV 314

Query: 571 TTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGD 630
           T  LALG  RM KK AIV+ LP VETLGC +VICSDKTGTLT N+M+V  +F  D +  +
Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374

Query: 631 ICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCNDSSLDFNEAKGVYE 690
                   +TG  Y   GEV+ +   V       +  +     +CND+ +  N       
Sbjct: 375 --------VTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTL----- 421

Query: 691 KVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMS 750
            +G+ TE AL  L  KM +       + K E                    FS ++K M+
Sbjct: 422 -MGKPTEGALIALAMKMGLDGLQQDYIRKAE------------------YPFSSEQKWMA 462

Query: 751 VYC-SPAKSSRAAVGNKMFVKGAPEGVIDRC-NYVRVGTTRVPLTGPVKEKIMAVIKEWG 808
           V C    +  R  +    F+KGA E VI  C  Y   G T   LT   +++ +   ++  
Sbjct: 463 VKCVHRTQQDRPEI---CFMKGAYEQVIKYCTTYQSKGQT---LTLTQQQRDVYQQEKAR 516

Query: 809 TGRDTLRCLALAT 821
            G   LR LALA+
Sbjct: 517 MGSAGLRVLALAS 529


>gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo
           sapiens]
          Length = 946

 Score =  239 bits (610), Expect = 8e-63
 Identities = 194/609 (31%), Positives = 302/609 (49%), Gaps = 66/609 (10%)

Query: 213 GGGRRVKRRNPGRQAVGHTEEDPPRVGTPWKEHTGPGPQEGSTMEAAHAKTTEECLAYFG 272
           GGGR+ +      +     E+   +     K+ T   P+E    +       E+    F 
Sbjct: 17  GGGRQYQALEKDEEEALIDEQSELKAIEKEKKVTALPPKEACKCQK------EDLARAFC 70

Query: 273 VSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAW 332
           V   TGL+   V +    +G NE  A+  + +W+  ++QF++ L+ +LL +A +S +   
Sbjct: 71  VDLHTGLSEFSVTQRRLAHGWNEFVADNSEPVWKKYLDQFKNPLILLLLGSALVSVLTKE 130

Query: 333 FEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSV 392
           +E+     TA       +L+++  A +   QE  +E ++E L +  P      R  +  +
Sbjct: 131 YEDAVSIATA-------VLVVVTVAFI---QEYRSEKSLEELTKMVPPECNCLREGK--L 178

Query: 393 QRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIKHTEPVPDP 452
           Q + AR++VPGD+V +++GD++PADIR+  +  T L VD+S  TGE+    K   P+   
Sbjct: 179 QHLLARELVPGDVVSLSIGDRIPADIRLTEV--TDLLVDESSFTGEAEPCSKTDSPLTGG 236

Query: 453 RAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAATEQDKTPLQQKLDEFG 512
             +     N++F GT +  G+  G+V  TG  ++ G++   M A E  KTPLQ+ +D  G
Sbjct: 237 GDLTT-LSNIVFMGTLVQYGRGQGVVIGTGESSQFGEVFKMMQAEETPKTPLQKSMDRLG 295

Query: 513 EQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVALAVAAIPEGLPAVITT 572
           +QL+     I   + LI          G S  +  +  F I V+LAVAAIPEGLP V+  
Sbjct: 296 KQLTLFSFGIIGLIMLI----------GWSQGKQLLSMFTIGVSLAVAAIPEGLPIVVMV 345

Query: 573 CLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGDIC 632
            L LG  RMAKK  IV+ LP VETLGC SV+CSDKTGTLT N+M+V ++   D +  ++ 
Sbjct: 346 TLVLGVLRMAKKRVIVKKLPIVETLGCCSVLCSDKTGTLTANEMTVTQLVTSDGLRAEVS 405

Query: 633 LLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCNDSSLDFNEAKGVYEKV 692
            +           P  EV+K    V  G+   LVE   +    N++ +  N        +
Sbjct: 406 GVGYDGQGTVCLLPSKEVIKEFSNVSVGK---LVEAGCV---ANNAVIRKNAV------M 453

Query: 693 GEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMSVY 752
           G+ TE AL  L  KM++  +D++           NS IR   KKE  + FS ++K M+V 
Sbjct: 454 GQPTEGALMALAMKMDL--SDIK-----------NSYIR---KKE--IPFSSEQKWMAVK 495

Query: 753 CSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGPVKEKIMAVIKEWGTGRD 812
           CS     +  +    F+KGA E VI  C     G   +PLT   +++   + +E   G  
Sbjct: 496 CSLKTEDQEDI---YFMKGALEEVIRYCTMYNNGGIPLPLT--PQQRSFCLQEEKRMGSL 550

Query: 813 TLRCLALAT 821
            LR LALA+
Sbjct: 551 GLRVLALAS 559


>gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]
          Length = 1020

 Score =  184 bits (467), Expect = 3e-46
 Identities = 151/555 (27%), Positives = 251/555 (45%), Gaps = 59/555 (10%)

Query: 260 HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 319
           H  + +E    + V  + GLT  + +  L + G N L        W     Q       +
Sbjct: 42  HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 101

Query: 320 LLLAACISFVLAWFE---EGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKE 376
           L + A + F+    +   E E +        V+  ++I       +QE  +   +++ K 
Sbjct: 102 LWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKN 161

Query: 377 YEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILT 436
             P+   V R   K   +I A ++V GD+VEV  GD+VPAD+RI  I S   +VD S LT
Sbjct: 162 MVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRI--ISSHGCKVDNSSLT 217

Query: 437 GESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAA 496
           GES    +  E   +      + +N+ F  TN   G A GIV  TG  T +G+I    + 
Sbjct: 218 GESEPQTRSPEFTHENPL---ETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASG 274

Query: 497 TEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVA 556
            E  +TP+  +++ F + ++ V   + V+ +++++      + G SW    I+     + 
Sbjct: 275 LEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL----IG 324

Query: 557 LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 616
           + VA +PEGL A +T CL L  +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M
Sbjct: 325 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 384

Query: 617 SVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCN 676
           +V  M+            N+     +T    G       P     +  L  +A +C    
Sbjct: 385 TVAHMWFD----------NQIHEADTTEDQSGATFDKRSPT----WTALSRIAGLCNRAV 430

Query: 677 DSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSV--IRQLM 734
             +   N +    +  G+A+E+AL   +E                   +C SV  +R   
Sbjct: 431 FKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSVRKMRDRN 472

Query: 735 KKEFTLEF-SRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLT 793
            K   + F S ++  +S++    +   +   + + +KGAPE ++DRC+ + V    +PL 
Sbjct: 473 PKVAEIPFNSTNKYQLSIH----EREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLD 528

Query: 794 GPVKEKIMAVIKEWG 808
             +++       E G
Sbjct: 529 KEMQDAFQNAYMELG 543


>gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]
          Length = 1013

 Score =  183 bits (465), Expect = 5e-46
 Identities = 147/556 (26%), Positives = 255/556 (45%), Gaps = 60/556 (10%)

Query: 260 HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 319
           H  + EE    +      GLT  + +  L + G N L        W     Q       +
Sbjct: 34  HKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 93

Query: 320 LLLAACISFVLAWFEEGEETITAFVEPF---VILLILIANAIVGVWQERNAENAIEALKE 376
           L + A + F+    + G E   +    +   V+  ++I       +QE  +   +E+ K 
Sbjct: 94  LWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKN 153

Query: 377 YEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILT 436
             P+   V R   K   ++ A ++V GD+VE+  GD+VPAD+RI++      +VD S LT
Sbjct: 154 MVPQQALVIREGEK--MQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGC--KVDNSSLT 209

Query: 437 GESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAA 496
           GES    +  +   D      + +N+ F  TN   G A G+V  TG  T +G+I    + 
Sbjct: 210 GESEPQTRSPDCTHDNPL---ETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASG 266

Query: 497 TEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVA 556
            E  KTP+  +++ F + ++ V   + V+ +++++      + G +W    I+     + 
Sbjct: 267 LEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSL------ILGYTWLEAVIFL----IG 316

Query: 557 LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 616
           + VA +PEGL A +T CL L  +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M
Sbjct: 317 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 376

Query: 617 SVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCN 676
           +V  M+  +++       ++   +G+++                     V L+ I  LCN
Sbjct: 377 TVAHMWFDNQIHEADTTEDQ---SGTSFDKSSHT--------------WVALSHIAGLCN 419

Query: 677 DSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQL 733
            +     +      K    G+A+E+AL                L  +E ++    ++R+ 
Sbjct: 420 RAVFKGGQDNIPVLKRDVAGDASESAL----------------LKCIELSSGSVKLMRER 463

Query: 734 MKKEFTLEF-SRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPL 792
            KK   + F S ++  +S++ +   +    +   + +KGAPE ++DRC+ + +     PL
Sbjct: 464 NKKVAEIPFNSTNKYQLSIHETEDPNDNRYL---LVMKGAPERILDRCSTILLQGKEQPL 520

Query: 793 TGPVKEKIMAVIKEWG 808
              +KE       E G
Sbjct: 521 DEEMKEAFQNAYLELG 536


>gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo
           sapiens]
          Length = 1023

 Score =  181 bits (459), Expect = 3e-45
 Identities = 155/561 (27%), Positives = 254/561 (45%), Gaps = 70/561 (12%)

Query: 260 HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 319
           H  + +E    +G   + GLT  +    L + G N L        W     Q       +
Sbjct: 44  HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSML 103

Query: 320 LLLAACISF----VLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 375
           L + A + F    + A  EE  +    ++   V+  ++I       +QE  +   +E+ K
Sbjct: 104 LWIGAILCFLAYSIQAATEEEPQNDNLYLG-VVLSAVVIITGCFSYYQEAKSSKIMESFK 162

Query: 376 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 435
              P+   V R   K    I A ++V GD+VEV  GD++PAD+RI  I +   +VD S L
Sbjct: 163 NMVPQQALVIRNGEK--MSINAEEVVVGDLVEVKGGDRIPADLRI--ISANGCKVDNSSL 218

Query: 436 TGESVSVIKHTEPVPDPRAVNQ-DKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQM 494
           TGES    +     PD    N  + +N+ F  TN   G A GIV  TG  T +G+I    
Sbjct: 219 TGESEPQTRS----PDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA 274

Query: 495 AATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIA 554
           +  E  +TP+  +++ F   ++ V   + V+ +++++      +   +W    I+     
Sbjct: 275 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSL------ILEYTWLEAVIFL---- 324

Query: 555 VALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTN 614
           + + VA +PEGL A +T CL L  +RMA+KN +V++L +VETLG TS ICSDKTGTLT N
Sbjct: 325 IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 384

Query: 615 QMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGL-VELATICA 673
           +M+V  M+  +++                   E +  +N   V   +     + L+ I  
Sbjct: 385 RMTVAHMWFDNQIH------------------EADTTENQSGVSFDKTSATWLALSRIAG 426

Query: 674 LCNDSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSV- 729
           LCN +    N+      K    G+A+E+AL   +E                    C SV 
Sbjct: 427 LCNRAVFQANQENLPILKRAVAGDASESALLKCIEL------------------CCGSVK 468

Query: 730 -IRQLMKKEFTLEF-SRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGT 787
            +R+   K   + F S ++  +S++ +P  S      + + +KGAPE ++DRC+ + +  
Sbjct: 469 EMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQ---HLLVMKGAPERILDRCSSILLHG 525

Query: 788 TRVPLTGPVKEKIMAVIKEWG 808
              PL   +K+       E G
Sbjct: 526 KEQPLDEELKDAFQNAYLELG 546


>gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo
           sapiens]
          Length = 992

 Score =  181 bits (459), Expect = 3e-45
 Identities = 155/561 (27%), Positives = 254/561 (45%), Gaps = 70/561 (12%)

Query: 260 HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 319
           H  + +E    +G   + GLT  +    L + G N L        W     Q       +
Sbjct: 13  HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSML 72

Query: 320 LLLAACISF----VLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 375
           L + A + F    + A  EE  +    ++   V+  ++I       +QE  +   +E+ K
Sbjct: 73  LWIGAILCFLAYSIQAATEEEPQNDNLYLG-VVLSAVVIITGCFSYYQEAKSSKIMESFK 131

Query: 376 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 435
              P+   V R   K    I A ++V GD+VEV  GD++PAD+RI  I +   +VD S L
Sbjct: 132 NMVPQQALVIRNGEK--MSINAEEVVVGDLVEVKGGDRIPADLRI--ISANGCKVDNSSL 187

Query: 436 TGESVSVIKHTEPVPDPRAVNQ-DKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQM 494
           TGES    +     PD    N  + +N+ F  TN   G A GIV  TG  T +G+I    
Sbjct: 188 TGESEPQTRS----PDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA 243

Query: 495 AATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIA 554
           +  E  +TP+  +++ F   ++ V   + V+ +++++      +   +W    I+     
Sbjct: 244 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSL------ILEYTWLEAVIFL---- 293

Query: 555 VALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTN 614
           + + VA +PEGL A +T CL L  +RMA+KN +V++L +VETLG TS ICSDKTGTLT N
Sbjct: 294 IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 353

Query: 615 QMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGL-VELATICA 673
           +M+V  M+  +++                   E +  +N   V   +     + L+ I  
Sbjct: 354 RMTVAHMWFDNQIH------------------EADTTENQSGVSFDKTSATWLALSRIAG 395

Query: 674 LCNDSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSV- 729
           LCN +    N+      K    G+A+E+AL   +E                    C SV 
Sbjct: 396 LCNRAVFQANQENLPILKRAVAGDASESALLKCIEL------------------CCGSVK 437

Query: 730 -IRQLMKKEFTLEF-SRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGT 787
            +R+   K   + F S ++  +S++ +P  S      + + +KGAPE ++DRC+ + +  
Sbjct: 438 EMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQ---HLLVMKGAPERILDRCSSILLHG 494

Query: 788 TRVPLTGPVKEKIMAVIKEWG 808
              PL   +K+       E G
Sbjct: 495 KEQPLDEELKDAFQNAYLELG 515


>gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]
          Length = 1023

 Score =  181 bits (459), Expect = 3e-45
 Identities = 155/561 (27%), Positives = 254/561 (45%), Gaps = 70/561 (12%)

Query: 260 HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 319
           H  + +E    +G   + GLT  +    L + G N L        W     Q       +
Sbjct: 44  HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSML 103

Query: 320 LLLAACISF----VLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 375
           L + A + F    + A  EE  +    ++   V+  ++I       +QE  +   +E+ K
Sbjct: 104 LWIGAILCFLAYSIQAATEEEPQNDNLYLG-VVLSAVVIITGCFSYYQEAKSSKIMESFK 162

Query: 376 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 435
              P+   V R   K    I A ++V GD+VEV  GD++PAD+RI  I +   +VD S L
Sbjct: 163 NMVPQQALVIRNGEK--MSINAEEVVVGDLVEVKGGDRIPADLRI--ISANGCKVDNSSL 218

Query: 436 TGESVSVIKHTEPVPDPRAVNQ-DKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQM 494
           TGES    +     PD    N  + +N+ F  TN   G A GIV  TG  T +G+I    
Sbjct: 219 TGESEPQTRS----PDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA 274

Query: 495 AATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIA 554
           +  E  +TP+  +++ F   ++ V   + V+ +++++      +   +W    I+     
Sbjct: 275 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSL------ILEYTWLEAVIFL---- 324

Query: 555 VALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTN 614
           + + VA +PEGL A +T CL L  +RMA+KN +V++L +VETLG TS ICSDKTGTLT N
Sbjct: 325 IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 384

Query: 615 QMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGL-VELATICA 673
           +M+V  M+  +++                   E +  +N   V   +     + L+ I  
Sbjct: 385 RMTVAHMWFDNQIH------------------EADTTENQSGVSFDKTSATWLALSRIAG 426

Query: 674 LCNDSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSV- 729
           LCN +    N+      K    G+A+E+AL   +E                    C SV 
Sbjct: 427 LCNRAVFQANQENLPILKRAVAGDASESALLKCIEL------------------CCGSVK 468

Query: 730 -IRQLMKKEFTLEF-SRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGT 787
            +R+   K   + F S ++  +S++ +P  S      + + +KGAPE ++DRC+ + +  
Sbjct: 469 EMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQ---HLLVMKGAPERILDRCSSILLHG 525

Query: 788 TRVPLTGPVKEKIMAVIKEWG 808
              PL   +K+       E G
Sbjct: 526 KEQPLDEELKDAFQNAYLELG 546


>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo
           sapiens]
          Length = 1029

 Score =  177 bits (450), Expect = 3e-44
 Identities = 154/558 (27%), Positives = 245/558 (43%), Gaps = 65/558 (11%)

Query: 260 HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 319
           H  T EE    + V  T G +  + K  L + G N +        W    +Q       +
Sbjct: 52  HKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLL 111

Query: 320 LLLAACISFVL----AWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 375
           L   A + FV      +F E E T        V+ +++I       +QE  +   +E+ K
Sbjct: 112 LWTGAILCFVAYSIQIYFNE-EPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFK 170

Query: 376 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 435
              P+   V R   K   +I  +++V GD+VE+  GD+VPAD+R+++ +    +VD S L
Sbjct: 171 NMVPQQALVIRGGEK--MQINVQEVVLGDLVEIKGGDRVPADLRLISAQGC--KVDNSSL 226

Query: 436 TGESVSVIKHTEPVPDPRAVNQ-DKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQM 494
           TGES    +     PD    N  + +N+ F  TN   G A GIV  TG  T +G+I    
Sbjct: 227 TGESEPQSRS----PDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLT 282

Query: 495 AATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIA 554
           +     +TP+  +++ F   ++ V   + V  + +++      + G  W    I+     
Sbjct: 283 SGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSL------LLGYGWLEAIIFL---- 332

Query: 555 VALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTN 614
           + + VA +PEGL A +T CL L  +RMA+KN +V++L +VETLG TS ICSDKTGTLT N
Sbjct: 333 IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 392

Query: 615 QMSVCKM-FIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICA 673
           +M+V  M F +   + D         TG T+                  D    LA I  
Sbjct: 393 RMTVAHMWFDMTVYEAD----TTEEQTGKTFTKSS--------------DTWFMLARIAG 434

Query: 674 LCNDSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVI 730
           LCN +    N+      K    G+A+E+AL   +E         +S S V      N  +
Sbjct: 435 LCNRADFKANQEILPIAKRATTGDASESALLKFIE---------QSYSSVAEMREKNPKV 485

Query: 731 RQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRV 790
            ++         S ++  MS++     S      + + +KGAPE +++ C+   +     
Sbjct: 486 AEIPFN------STNKYQMSIHLREDSSQT----HVLMMKGAPERILEFCSTFLLNGQEY 535

Query: 791 PLTGPVKEKIMAVIKEWG 808
            +   +KE       E G
Sbjct: 536 SMNDEMKEAFQNAYLELG 553


>gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]
          Length = 1035

 Score =  175 bits (444), Expect = 1e-43
 Identities = 159/580 (27%), Positives = 259/580 (44%), Gaps = 69/580 (11%)

Query: 260 HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 319
           H  +  E    +  S T GL+       L + G N L    G   +     Q    L  +
Sbjct: 55  HQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCL 114

Query: 320 LLLAACISFVLAWFEEGEETITAFVEPFV---ILLILIANAIVGVWQERNAENAIEALKE 376
           + +AA I  +    +  E  +T     ++   ++ +++     G +QE  + N I + K 
Sbjct: 115 MWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKN 174

Query: 377 YEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILT 436
             P+   V R   K   +I A  +V GD+VE+  GD+VPADIRILA +    +VD S LT
Sbjct: 175 LVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSSLT 230

Query: 437 GESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAA 496
           GES    +  E   +      + +N+ F  T    G   G+V  TG  T IG+I    + 
Sbjct: 231 GESEPQTRSPECTHESPL---ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASG 287

Query: 497 TEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVA 556
            E +KTP+  +++ F + ++ +  L     +++ +        G ++ R  +++    +A
Sbjct: 288 VENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVFF----MA 337

Query: 557 LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 616
           + VA +PEGL A +T CL+L  +R+A KN +V++L +VETLG TSVICSDKTGTLT N+M
Sbjct: 338 IVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRM 397

Query: 617 SVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCN 676
           +V  ++  + +       ++   +G T+    E  +               L  +  LCN
Sbjct: 398 TVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWR--------------ALCRVLTLCN 440

Query: 677 DSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVER-ANACNSVIRQ 732
            ++    +      K   +G+A+ETAL    E      T   ++   +R    C      
Sbjct: 441 RAAFKSGQDAVPVPKRIVIGDASETALLKFSEL-----TLGNAMGYRDRFPKVCEIPFNS 495

Query: 733 LMKKEF---TLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTR 789
             K +    TLE  RD + + V                 +KGAPE V++RC+ + +    
Sbjct: 496 TNKFQLSIHTLEDPRDPRHLLV-----------------MKGAPERVLERCSSILIKGQE 538

Query: 790 VPLTGPVKEKIM-AVIKEWGTGRDTLRC--LALATRDTPP 826
           +PL    +E    A +   G G   L    L L  +D PP
Sbjct: 539 LPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPP 578


>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
          Length = 1039

 Score =  157 bits (397), Expect = 4e-38
 Identities = 144/545 (26%), Positives = 239/545 (43%), Gaps = 70/545 (12%)

Query: 260 HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNEL-PAEEGKTLWELVIEQFE--DLL 316
           H  +  E    +G     GL+  +    L + G N L P ++   + + + +      +L
Sbjct: 59  HKLSNRELEEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSIL 118

Query: 317 VRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKE 376
           + +      I++ + +  +   ++       V+ L++I   I   +QE  + N + +  +
Sbjct: 119 LWVGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNK 178

Query: 377 YEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILT 436
             P+   V R   K    I +  +V GDIVEV  GD++PADIR+L+  S   RVD S LT
Sbjct: 179 MIPQQALVIRDSEKKT--IPSEQLVVGDIVEVKGGDQIPADIRVLS--SQGCRVDNSSLT 234

Query: 437 GESV-----SVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIR 491
           GES      S   H  P+        + KN+ F  T    G   G+V  TG  T IG I 
Sbjct: 235 GESEPQPRSSEFTHENPL--------ETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIA 286

Query: 492 DQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYF 551
              +    +KTP+  +++ F   ++ V   I +  ++I +          S     +   
Sbjct: 287 SLASGVGNEKTPIAIEIEHFVHIVAGVAVSIGILFFIIAV----------SLKYQVLDSI 336

Query: 552 KIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTL 611
              + + VA +PEGL A +T  L+L  +RMAKKN +V++L +VETLG TS+ICSDKTGTL
Sbjct: 337 IFLIGIIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTL 396

Query: 612 TTNQMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATI 671
           T N+M+V  ++            N+  +  ++     +V                 L+ I
Sbjct: 397 TQNRMTVAHLWFD----------NQIFVADTSEDHSNQVFDQSSRT-------WASLSKI 439

Query: 672 CALCNDSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVERANACNS 728
             LCN +     +      K   +G+A+ETAL    E   V   DV  + K  R      
Sbjct: 440 ITLCNRAEFKPGQENVPIMKKAVIGDASETALLKFSE---VILGDVMEIRKRNR------ 490

Query: 729 VIRQLMKKEFTLEFSRDRK-SMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGT 787
                  K   + F+   K  +S++       +  +   M +KGAPE ++++C+ + +  
Sbjct: 491 -------KVAEIPFNSTNKFQLSIHEMDDPHGKRFL---MVMKGAPERILEKCSTIMING 540

Query: 788 TRVPL 792
              PL
Sbjct: 541 EEHPL 545


>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo
           sapiens]
          Length = 1198

 Score =  153 bits (387), Expect = 6e-37
 Identities = 171/625 (27%), Positives = 261/625 (41%), Gaps = 128/625 (20%)

Query: 278 GLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWF---- 333
           G  PD  KR  + +G N +P ++ KT  +LV E  +D+ + IL +AA IS  L+++    
Sbjct: 70  GTAPDLEKRK-QIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPG 128

Query: 334 -------------EEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPE 380
                        E+  E    ++E   ILL +I   +V  + + + E     L+    +
Sbjct: 129 EGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQ 188

Query: 381 MGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESV 440
             K        V +I   +IV GDI +V  GD +PAD   L I+   L++D+S LTGES 
Sbjct: 189 EQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPAD--GLFIQGNDLKIDESSLTGESD 246

Query: 441 SVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIG------------ 488
            V K           + DK  ML SGT++  G    +V   GV ++ G            
Sbjct: 247 QVRK-----------SVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEE 295

Query: 489 --------KIRDQMAATE----------------------QDKTPLQQKLDEFGEQLSK- 517
                   K +D  AA E                      ++K+ LQ KL +   Q+ K 
Sbjct: 296 EEKKDKKAKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKA 355

Query: 518 --VISLICVAVWLINIGHFNDPVHGGSWF--------RGAIYYFKIAVALAVAAIPEGLP 567
             V+S I V + ++        V+   W         +  + +F I V + V A+PEGLP
Sbjct: 356 GLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLP 415

Query: 568 AVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKV 627
             +T  LA   ++M K N +VR L + ET+G  + ICSDKTGTLTTN+M+V + ++    
Sbjct: 416 LAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYV---- 471

Query: 628 DGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCNDSSLDFNEAKG 687
            GD+                 + + +   +     + L+    I +      L   +   
Sbjct: 472 -GDV---------------HYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGA 515

Query: 688 VYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKEFTLEFSRDRK 747
           +  +VG  TE  L   V  +      VRS    E+           + K +T  F+  RK
Sbjct: 516 LPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEK-----------LYKVYT--FNSVRK 562

Query: 748 SMS-VYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYV--RVGTTRVPLTGPVKEKIMAVI 804
           SMS V   P +S R      M+ KGA E V+ +C  +    G  RV       E +  VI
Sbjct: 563 SMSTVIKLPDESFR------MYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVI 616

Query: 805 KEWGTGRDTLRCLALATRDTPPKRE 829
           +      D LR + +A RD P   E
Sbjct: 617 EPMAC--DGLRTICVAYRDFPSSPE 639


>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
           sapiens]
          Length = 1170

 Score =  142 bits (358), Expect = 1e-33
 Identities = 162/628 (25%), Positives = 260/628 (41%), Gaps = 138/628 (21%)

Query: 281 PDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWF------- 333
           P  +++  + +G N +P ++ KT  ELV E  +D+ + IL +AA IS VL+++       
Sbjct: 70  PADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEEN 129

Query: 334 ----------EEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGK 383
                     E+  E    ++E   IL  +I   +V  + + + E     L+    +  K
Sbjct: 130 ELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQK 189

Query: 384 VYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVI 443
                   + ++   +IV GDI +V  GD +PAD   + I+   L++D+S LTGES  V 
Sbjct: 190 FSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADG--ILIQGNDLKIDESSLTGESDHVK 247

Query: 444 KHTEPVPDPRAVNQDKKNMLFSGTNIAAGK------ALGIVATTGV-------------- 483
           K           + DK  ML SGT++  G       A+G+ + TG+              
Sbjct: 248 K-----------SLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGE 296

Query: 484 ----GTEIGKIRDQMAATEQD-------------------------------KTPLQQKL 508
               G + G   ++  A  QD                               K+ LQ KL
Sbjct: 297 KKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKL 356

Query: 509 DEFGEQLSKVISLICVAVWLINIGHF---NDPVHGGSWFRGA--------IYYFKIAVAL 557
                Q+ K   L+      I I +F   N  ++   W            + +F I + +
Sbjct: 357 TRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITV 416

Query: 558 AVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMS 617
            V A+PEGLP  +T  LA   ++M K N +VR L + ET+G  + ICSDKTGTLT N+M+
Sbjct: 417 LVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMT 476

Query: 618 VCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCND 677
           V + +I                 G  +  +   + +     P   D +V   +I +    
Sbjct: 477 VVQAYI-----------------GGIHYRQ---IPSPDVFLPKVLDLIVNGISINSAYTS 516

Query: 678 SSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKE 737
             L   +  G+  +VG  TE AL   V       TD++   +  R    N V  + + K 
Sbjct: 517 KILPPEKEGGLPRQVGNKTECALLGFV-------TDLKQDYQAVR----NEVPEEKLYKV 565

Query: 738 FTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYV--RVGTTRVPLTGP 795
           +T  F+  RKSMS             G +M+ KGA E ++ +CN +  R G   VP    
Sbjct: 566 YT--FNSVRKSMSTVIRNPNG-----GFRMYSKGASEIILRKCNRILDRKGEA-VPFKNK 617

Query: 796 VKEKIMAVIKEWGTGRDTLRCLALATRD 823
            ++ ++  + E     D LR + +A RD
Sbjct: 618 DRDDMVRTVIE-PMACDGLRTICIAYRD 644


>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
           sapiens]
          Length = 1205

 Score =  142 bits (358), Expect = 1e-33
 Identities = 162/628 (25%), Positives = 260/628 (41%), Gaps = 138/628 (21%)

Query: 281 PDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWF------- 333
           P  +++  + +G N +P ++ KT  ELV E  +D+ + IL +AA IS VL+++       
Sbjct: 70  PADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEEN 129

Query: 334 ----------EEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGK 383
                     E+  E    ++E   IL  +I   +V  + + + E     L+    +  K
Sbjct: 130 ELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQK 189

Query: 384 VYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVI 443
                   + ++   +IV GDI +V  GD +PAD   + I+   L++D+S LTGES  V 
Sbjct: 190 FSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADG--ILIQGNDLKIDESSLTGESDHVK 247

Query: 444 KHTEPVPDPRAVNQDKKNMLFSGTNIAAGK------ALGIVATTGV-------------- 483
           K           + DK  ML SGT++  G       A+G+ + TG+              
Sbjct: 248 K-----------SLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGE 296

Query: 484 ----GTEIGKIRDQMAATEQD-------------------------------KTPLQQKL 508
               G + G   ++  A  QD                               K+ LQ KL
Sbjct: 297 KKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKL 356

Query: 509 DEFGEQLSKVISLICVAVWLINIGHF---NDPVHGGSWFRGA--------IYYFKIAVAL 557
                Q+ K   L+      I I +F   N  ++   W            + +F I + +
Sbjct: 357 TRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITV 416

Query: 558 AVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMS 617
            V A+PEGLP  +T  LA   ++M K N +VR L + ET+G  + ICSDKTGTLT N+M+
Sbjct: 417 LVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMT 476

Query: 618 VCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCND 677
           V + +I                 G  +  +   + +     P   D +V   +I +    
Sbjct: 477 VVQAYI-----------------GGIHYRQ---IPSPDVFLPKVLDLIVNGISINSAYTS 516

Query: 678 SSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKE 737
             L   +  G+  +VG  TE AL   V       TD++   +  R    N V  + + K 
Sbjct: 517 KILPPEKEGGLPRQVGNKTECALLGFV-------TDLKQDYQAVR----NEVPEEKLYKV 565

Query: 738 FTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYV--RVGTTRVPLTGP 795
           +T  F+  RKSMS             G +M+ KGA E ++ +CN +  R G   VP    
Sbjct: 566 YT--FNSVRKSMSTVIRNPNG-----GFRMYSKGASEIILRKCNRILDRKGEA-VPFKNK 617

Query: 796 VKEKIMAVIKEWGTGRDTLRCLALATRD 823
            ++ ++  + E     D LR + +A RD
Sbjct: 618 DRDDMVRTVIE-PMACDGLRTICIAYRD 644


>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
           sapiens]
          Length = 1176

 Score =  141 bits (356), Expect = 2e-33
 Identities = 163/644 (25%), Positives = 261/644 (40%), Gaps = 141/644 (21%)

Query: 281 PDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWFE--EGEE 338
           P  ++R    +G N +P ++ KT  +LV E  +D+ + IL +AA +S  L++++  EG+ 
Sbjct: 75  PADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFYQPPEGDN 134

Query: 339 TI--------------TAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKV 384
            +              T ++E   ILL ++   +V  + + + E     L+    +  K 
Sbjct: 135 ALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKF 194

Query: 385 YRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIK 444
                  V +I   DI  GDI +V  GD +PAD   + I+   L++D+S LTGES  V K
Sbjct: 195 TVIRGGQVIQIPVADITVGDIAQVKYGDLLPADG--ILIQGNDLKIDESSLTGESDHVKK 252

Query: 445 HTEPVPDPRAVNQDKKNMLFSGTNIAAGK------ALGIVATTGV--------------- 483
                      + DK  +L SGT++  G       A+G+ + TG+               
Sbjct: 253 -----------SLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKK 301

Query: 484 ---------GTEIGKIRDQMAATEQD-------------------------------KTP 503
                      + G I ++  A  QD                               K+ 
Sbjct: 302 DEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKSV 361

Query: 504 LQQKLDEFGEQLSKVISLICVAVWLINIGHFNDP---VHGGSWFRGA--------IYYFK 552
           LQ KL +   Q+ K   L+     +I + +F      V    W            + +F 
Sbjct: 362 LQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFI 421

Query: 553 IAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLT 612
           I V + V A+PEGLP  +T  LA   ++M K N +VR L + ET+G  + ICSDKTGTLT
Sbjct: 422 IGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLT 481

Query: 613 TNQMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATIC 672
            N+M+V + +I +K    +              PE E       + P     LV   ++ 
Sbjct: 482 MNRMTVVQAYINEKHYKKV--------------PEPEA------IPPNILSYLVTGISVN 521

Query: 673 ALCNDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQ 732
                  L   +  G+   VG  TE AL  L+  +     DVR           N +  +
Sbjct: 522 CAYTSKILPPEKEGGLPRHVGNKTECALLGLLLDLKRDYQDVR-----------NEIPEE 570

Query: 733 LMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPL 792
            + K +T  F+  RKSMS     +  S      ++F KGA E ++ +C  +        +
Sbjct: 571 ALYKVYT--FNSVRKSMSTVLKNSDGS-----YRIFSKGASEIILKKCFKILSANGEAKV 623

Query: 793 TGP-VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDD 835
             P  ++ I+  + E     + LR + LA RD P    E   D+
Sbjct: 624 FRPRDRDDIVKTVIE-PMASEGLRTICLAFRDFPAGEPEPEWDN 666


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,459,227
Number of Sequences: 37866
Number of extensions: 1959200
Number of successful extensions: 6812
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 115
Number of HSP's that attempted gapping in prelim test: 6518
Number of HSP's gapped (non-prelim): 334
length of query: 879
length of database: 18,247,518
effective HSP length: 111
effective length of query: 768
effective length of database: 14,044,392
effective search space: 10786093056
effective search space used: 10786093056
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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