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Search of human proteins with 117606362
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|117606362 anterior pharynx defective 1 homolog A isoform 1
[Homo sapiens]
(265 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|117606362 anterior pharynx defective 1 homolog A isoform 1 [H... 523 e-149
gi|117606357 anterior pharynx defective 1 homolog A isoform 2 [H... 484 e-137
gi|50726954 presenilin stabilization factor-like isoform 1 [Homo... 299 1e-81
gi|224548987 presenilin stabilization factor-like isoform 2 [Hom... 218 6e-57
gi|153252026 chloride channel 4 [Homo sapiens] 32 0.57
gi|150418005 protein tyrosine phosphatase, non-receptor type 21 ... 30 2.8
gi|197276623 solute carrier family 6 (neurotransmitter transport... 30 2.8
gi|54607094 solute carrier family 6 (neurotransmitter transporte... 30 2.8
gi|14042925 ring finger protein 26 [Homo sapiens] 29 3.7
gi|19923665 BRI3-binding protein [Homo sapiens] 29 3.7
gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo s... 28 6.3
gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo s... 28 6.3
gi|21729876 ATP-binding cassette, sub-family C, member 11 isofor... 28 8.3
gi|21729873 ATP-binding cassette, sub-family C, member 11 isofor... 28 8.3
gi|15149474 ATP-binding cassette, sub-family C, member 11 isofor... 28 8.3
gi|116063556 G-protein coupled receptor 88 [Homo sapiens] 28 8.3
>gi|117606362 anterior pharynx defective 1 homolog A isoform 1 [Homo
sapiens]
Length = 265
Score = 523 bits (1346), Expect = e-149
Identities = 265/265 (100%), Positives = 265/265 (100%)
Query: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60
MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT
Sbjct: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60
Query: 61 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV 120
DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV
Sbjct: 61 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV 120
Query: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD 180
SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD
Sbjct: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD 180
Query: 181 ACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQ 240
ACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQ
Sbjct: 181 ACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQ 240
Query: 241 RSLLCRRQEDSRVMVYSALRIPPED 265
RSLLCRRQEDSRVMVYSALRIPPED
Sbjct: 241 RSLLCRRQEDSRVMVYSALRIPPED 265
>gi|117606357 anterior pharynx defective 1 homolog A isoform 2 [Homo
sapiens]
Length = 247
Score = 484 bits (1247), Expect = e-137
Identities = 245/246 (99%), Positives = 246/246 (100%)
Query: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60
MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT
Sbjct: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60
Query: 61 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV 120
DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV
Sbjct: 61 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV 120
Query: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD 180
SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD
Sbjct: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD 180
Query: 181 ACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQ 240
ACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQ
Sbjct: 181 ACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQ 240
Query: 241 RSLLCR 246
RSLLC+
Sbjct: 241 RSLLCK 246
>gi|50726954 presenilin stabilization factor-like isoform 1 [Homo
sapiens]
Length = 257
Score = 299 bits (766), Expect = 1e-81
Identities = 147/257 (57%), Positives = 193/257 (75%), Gaps = 4/257 (1%)
Query: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60
M AAVFFGC F+AFGPA AL++ T+A +PLR+I L+AGAFFWLVSLL++S+VWF+ +
Sbjct: 1 MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII 60
Query: 61 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV 120
D D Q LLIFGA VSV +QE+FRFAYYKLLKKA EGL S++ +P S+R +AYV
Sbjct: 61 DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAP-SMRLLAYV 119
Query: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD 180
SGL FGI+SGVFS +N L+D+LGPG VGIHGDSP +FL SAF+T IILLH FWG+VFFD
Sbjct: 120 SGLGFGIMSGVFSFVNTLSDSLGPGTVGIHGDSPQFFLYSAFMTLVIILLHVFWGIVFFD 179
Query: 181 ACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQ 240
CE++++ L +V+ +HLL S TF++ +Y +L + + V MG WAF+ AGGS RS++
Sbjct: 180 GCEKKKWGILLIVLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLK 239
Query: 241 RSLLCRRQEDSRVMVYS 257
LLC +D ++Y+
Sbjct: 240 LCLLC---QDKNFLLYN 253
>gi|224548987 presenilin stabilization factor-like isoform 2 [Homo
sapiens]
Length = 216
Score = 218 bits (554), Expect = 6e-57
Identities = 117/257 (45%), Positives = 158/257 (61%), Gaps = 45/257 (17%)
Query: 1 MGAAVFFGCTFVAFGPAFALFLITVAGDPLRVIILVAGAFFWLVSLLLASVVWFILVHVT 60
M AAVFFGC F+AFGPA AL++ T+A +PLR+I L+AGAFFWLVSLL++S+VWF+ +
Sbjct: 1 MTAAVFFGCAFIAFGPALALYVFTIATEPLRIIFLIAGAFFWLVSLLISSLVWFMARVII 60
Query: 61 DRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYV 120
D D Q LLIFGA VSV +QE+FRFAYYKLLKKA EGL S++ +P S+R +AY
Sbjct: 61 DNKDGPTQKYLLIFGAFVSVYIQEMFRFAYYKLLKKASEGLKSINPGETAP-SMRLLAY- 118
Query: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFFD 180
AF+T IILLH FWG+VFFD
Sbjct: 119 ----------------------------------------AFMTLVIILLHVFWGIVFFD 138
Query: 181 ACERRRYWALGLVVGSHLLTSGLTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQ 240
CE++++ L +V+ +HLL S TF++ +Y +L + + V MG WAF+ AGGS RS++
Sbjct: 139 GCEKKKWGILLIVLLTHLLVSAQTFISSYYGINLASAFIILVLMGTWAFLAAGGSCRSLK 198
Query: 241 RSLLCRRQEDSRVMVYS 257
LLC +D ++Y+
Sbjct: 199 LCLLC---QDKNFLLYN 212
>gi|153252026 chloride channel 4 [Homo sapiens]
Length = 760
Score = 32.0 bits (71), Expect = 0.57
Identities = 20/66 (30%), Positives = 30/66 (45%), Gaps = 6/66 (9%)
Query: 196 SHLLTSGLTFLNPWYEASLLPIYAVTVSMGLWAFITAGGSLRSIQRSLLCRRQEDSRVMV 255
S L+ + + PWY A L P + V GLW G+L CRR++ +R+
Sbjct: 314 SRLVLFYVEYHTPWYMAELFPFILLGVFGGLW------GTLFIRCNIAWCRRRKTTRLGK 367
Query: 256 YSALRI 261
Y L +
Sbjct: 368 YPVLEV 373
>gi|150418005 protein tyrosine phosphatase, non-receptor type 21
[Homo sapiens]
Length = 1174
Score = 29.6 bits (65), Expect = 2.8
Identities = 17/56 (30%), Positives = 30/56 (53%), Gaps = 7/56 (12%)
Query: 69 YGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYVSGLS 124
+G++ + +VS L QE+ R+ YY LKK +G P ++ Q ++GL+
Sbjct: 99 FGVVFYVPSVSQLQQEITRYQYYLQLKKD-------ILEGSIPCTLEQAIQLAGLA 147
>gi|197276623 solute carrier family 6 (neurotransmitter transporter,
taurine), member 6 isoform a [Homo sapiens]
Length = 620
Score = 29.6 bits (65), Expect = 2.8
Identities = 15/59 (25%), Positives = 26/59 (44%)
Query: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFF 179
SG SF +FS++ +A G + + P + ++ L TFW ++FF
Sbjct: 334 SGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFF 392
>gi|54607094 solute carrier family 6 (neurotransmitter transporter,
taurine), member 6 isoform a [Homo sapiens]
Length = 620
Score = 29.6 bits (65), Expect = 2.8
Identities = 15/59 (25%), Positives = 26/59 (44%)
Query: 121 SGLSFGIISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVVFF 179
SG SF +FS++ +A G + + P + ++ L TFW ++FF
Sbjct: 334 SGTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFF 392
>gi|14042925 ring finger protein 26 [Homo sapiens]
Length = 433
Score = 29.3 bits (64), Expect = 3.7
Identities = 30/86 (34%), Positives = 39/86 (45%), Gaps = 14/86 (16%)
Query: 30 LRVIILVAGAFFWLVSLLLASVVWFI-----LVHVTDRSDARLQYGLLIFGAAVSVLLQE 84
L V+ LV F LVS LLAS+ W + L H S L G+L+ ++ L++
Sbjct: 15 LDVLTLVLDLNFLLVSSLLASLAWLLAFVYNLPHTVLTSLLHLGRGVLL---SLLALIEA 71
Query: 85 VFRF------AYYKLLKKADEGLASL 104
V RF A LL GL SL
Sbjct: 72 VVRFTCGGLQALCTLLYSCCSGLESL 97
>gi|19923665 BRI3-binding protein [Homo sapiens]
Length = 251
Score = 29.3 bits (64), Expect = 3.7
Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 11/64 (17%)
Query: 6 FFGCTFVAFGPAFALFLITVA-----------GDPLRVIILVAGAFFWLVSLLLASVVWF 54
+F V+ PA AL L+ V G V+ +V G FFW+V ++L S+
Sbjct: 112 YFSPASVSSSPARALLLVGVVLLAYWFLSLTLGFTFSVLHVVFGRFFWIVRVVLFSMSCV 171
Query: 55 ILVH 58
++H
Sbjct: 172 YILH 175
>gi|109948288 solute carrier family 7, member 2 isoform 1 [Homo
sapiens]
Length = 697
Score = 28.5 bits (62), Expect = 6.3
Identities = 17/49 (34%), Positives = 27/49 (55%), Gaps = 3/49 (6%)
Query: 199 LTSGLTFLNPWY---EASLLPIYAVTVSMGLWAFITAGGSLRSIQRSLL 244
+++ LT + P+Y E S LP+ V G ++ A GSL ++ SLL
Sbjct: 346 VSAALTLMMPYYLLDEKSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLL 394
>gi|134304858 solute carrier family 7, member 2 isoform 2 [Homo
sapiens]
Length = 658
Score = 28.5 bits (62), Expect = 6.3
Identities = 17/49 (34%), Positives = 27/49 (55%), Gaps = 3/49 (6%)
Query: 199 LTSGLTFLNPWY---EASLLPIYAVTVSMGLWAFITAGGSLRSIQRSLL 244
+++ LT + P+Y E S LP+ V G ++ A GSL ++ SLL
Sbjct: 306 VSAALTLMMPYYLLDEKSPLPVAFEYVGWGPAKYVVAAGSLCALSTSLL 354
>gi|21729876 ATP-binding cassette, sub-family C, member 11 isoform b
[Homo sapiens]
Length = 1344
Score = 28.1 bits (61), Expect = 8.3
Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 18/105 (17%)
Query: 41 FWLVSLLLASVVWFILVHVTDRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEG 100
F ++SL++ +V+ + V L +L+ GA + V+ F YY + KKA
Sbjct: 941 FLVLSLMVIAVLLIVSV---------LSPYILLMGAIIMVIC-----FIYYMMFKKAIGV 986
Query: 101 LASLSEDGRSPISIRQMAYVSGLS----FGIISGVFSVINILADA 141
L RSP+ + + GLS +G S L DA
Sbjct: 987 FKRLENYSRSPLFSHILNSLQGLSSIHVYGKTEDFISQFKRLTDA 1031
>gi|21729873 ATP-binding cassette, sub-family C, member 11 isoform a
[Homo sapiens]
Length = 1382
Score = 28.1 bits (61), Expect = 8.3
Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 18/105 (17%)
Query: 41 FWLVSLLLASVVWFILVHVTDRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEG 100
F ++SL++ +V+ + V L +L+ GA + V+ F YY + KKA
Sbjct: 941 FLVLSLMVIAVLLIVSV---------LSPYILLMGAIIMVIC-----FIYYMMFKKAIGV 986
Query: 101 LASLSEDGRSPISIRQMAYVSGLS----FGIISGVFSVINILADA 141
L RSP+ + + GLS +G S L DA
Sbjct: 987 FKRLENYSRSPLFSHILNSLQGLSSIHVYGKTEDFISQFKRLTDA 1031
>gi|15149474 ATP-binding cassette, sub-family C, member 11 isoform a
[Homo sapiens]
Length = 1382
Score = 28.1 bits (61), Expect = 8.3
Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 18/105 (17%)
Query: 41 FWLVSLLLASVVWFILVHVTDRSDARLQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEG 100
F ++SL++ +V+ + V L +L+ GA + V+ F YY + KKA
Sbjct: 941 FLVLSLMVIAVLLIVSV---------LSPYILLMGAIIMVIC-----FIYYMMFKKAIGV 986
Query: 101 LASLSEDGRSPISIRQMAYVSGLS----FGIISGVFSVINILADA 141
L RSP+ + + GLS +G S L DA
Sbjct: 987 FKRLENYSRSPLFSHILNSLQGLSSIHVYGKTEDFISQFKRLTDA 1031
>gi|116063556 G-protein coupled receptor 88 [Homo sapiens]
Length = 384
Score = 28.1 bits (61), Expect = 8.3
Identities = 28/111 (25%), Positives = 46/111 (41%), Gaps = 9/111 (8%)
Query: 67 LQYGLLIFGAAVSVLLQEVFRFAYYKLLKKADEGLASLSEDGRSPISIRQMAYVSGLSFG 126
L+ GLL G VS+L + Y L+ +A +L + R A + LS+
Sbjct: 115 LRGGLLGLGLTVSLLSHCLVALNRYLLITRAPATYQALYQR-------RHTAGMLALSWA 167
Query: 127 IISGVFSVINILADALGPGVVGIHGDSPYYFLTSAFLTAAIILLHTFWGVV 177
+ G+ ++ A G +H P +A L +LLH + G+V
Sbjct: 168 LALGLVLLLPPWAPRPGAAPPRVH--YPALLAAAALLAQTALLLHCYLGIV 216
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.330 0.144 0.445
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,805,756
Number of Sequences: 37866
Number of extensions: 330896
Number of successful extensions: 974
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 966
Number of HSP's gapped (non-prelim): 17
length of query: 265
length of database: 18,247,518
effective HSP length: 100
effective length of query: 165
effective length of database: 14,460,918
effective search space: 2386051470
effective search space used: 2386051470
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.