Search of human proteins with 10863945

Search of human proteins with 10863945

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10863945 ATP-dependent DNA helicase II [Homo sapiens]
         (732 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10863945 ATP-dependent DNA helicase II [Homo sapiens]             1453   0.0  
gi|20127519 TPX2, microtubule-associated protein homolog [Homo s...    34   0.42 
gi|118498368 kinectin 1 isoform c [Homo sapiens]                       32   1.6  
gi|156119605 general transcription factor IIIC 4 [Homo sapiens]        32   1.6  
gi|153791300 SDA1 domain containing 1 [Homo sapiens]                   32   1.6  
gi|118498356 kinectin 1 isoform a [Homo sapiens]                       32   2.7  
gi|33620775 kinectin 1 isoform a [Homo sapiens]                        32   2.7  
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo...    32   2.7  
gi|223468617 family with sequence similarity 75, member C1 [Homo...    31   3.6  
gi|54633319 PDZ domain-containing guanine nucleotide exchange fa...    31   4.7  
gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]           30   6.1  
gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]           30   6.1  

>gi|10863945 ATP-dependent DNA helicase II [Homo sapiens]
          Length = 732

 Score = 1453 bits (3761), Expect = 0.0
 Identities = 732/732 (100%), Positives = 732/732 (100%)

Query: 1   MVRSGNKAAVVLCMDVGFTMSNSIPGIESPFEQAKKVITMFVQRQVFAENKDEIALVLFG 60
           MVRSGNKAAVVLCMDVGFTMSNSIPGIESPFEQAKKVITMFVQRQVFAENKDEIALVLFG
Sbjct: 1   MVRSGNKAAVVLCMDVGFTMSNSIPGIESPFEQAKKVITMFVQRQVFAENKDEIALVLFG 60

Query: 61  TDGTDNPLSGGDQYQNITVHRHLMLPDFDLLEDIESKIQPGSQQADFLDALIVSMDVIQH 120
           TDGTDNPLSGGDQYQNITVHRHLMLPDFDLLEDIESKIQPGSQQADFLDALIVSMDVIQH
Sbjct: 61  TDGTDNPLSGGDQYQNITVHRHLMLPDFDLLEDIESKIQPGSQQADFLDALIVSMDVIQH 120

Query: 121 ETIGKKFEKRHIEIFTDLSSRFSKSQLDIIIHSLKKCDISLQFFLPFSLGKEDGSGDRGD 180
           ETIGKKFEKRHIEIFTDLSSRFSKSQLDIIIHSLKKCDISLQFFLPFSLGKEDGSGDRGD
Sbjct: 121 ETIGKKFEKRHIEIFTDLSSRFSKSQLDIIIHSLKKCDISLQFFLPFSLGKEDGSGDRGD 180

Query: 181 GPFRLGGHGPSFPLKGITEQQKEGLEIVKMVMISLEGEDGLDEIYSFSESLRKLCVFKKI 240
           GPFRLGGHGPSFPLKGITEQQKEGLEIVKMVMISLEGEDGLDEIYSFSESLRKLCVFKKI
Sbjct: 181 GPFRLGGHGPSFPLKGITEQQKEGLEIVKMVMISLEGEDGLDEIYSFSESLRKLCVFKKI 240

Query: 241 ERHSIHWPCRLTIGSNLSIRIAAYKSILQERVKKTWTVVDAKTLKKEDIQKETVYCLNDD 300
           ERHSIHWPCRLTIGSNLSIRIAAYKSILQERVKKTWTVVDAKTLKKEDIQKETVYCLNDD
Sbjct: 241 ERHSIHWPCRLTIGSNLSIRIAAYKSILQERVKKTWTVVDAKTLKKEDIQKETVYCLNDD 300

Query: 301 DETEVLKEDIIQGFRYGSDIVPFSKVDEEQMKYKSEGKCFSVLGFCKSSQVQRRFFMGNQ 360
           DETEVLKEDIIQGFRYGSDIVPFSKVDEEQMKYKSEGKCFSVLGFCKSSQVQRRFFMGNQ
Sbjct: 301 DETEVLKEDIIQGFRYGSDIVPFSKVDEEQMKYKSEGKCFSVLGFCKSSQVQRRFFMGNQ 360

Query: 361 VLKVFAARDDEAAAVALSSLIHALDDLDMVAIVRYAYDKRANPQVGVAFPHIKHNYECLV 420
           VLKVFAARDDEAAAVALSSLIHALDDLDMVAIVRYAYDKRANPQVGVAFPHIKHNYECLV
Sbjct: 361 VLKVFAARDDEAAAVALSSLIHALDDLDMVAIVRYAYDKRANPQVGVAFPHIKHNYECLV 420

Query: 421 YVQLPFMEDLRQYMFSSLKNSKKYAPTEAQLNAVDALIDSMSLAKKDEKTDTLEDLFPTT 480
           YVQLPFMEDLRQYMFSSLKNSKKYAPTEAQLNAVDALIDSMSLAKKDEKTDTLEDLFPTT
Sbjct: 421 YVQLPFMEDLRQYMFSSLKNSKKYAPTEAQLNAVDALIDSMSLAKKDEKTDTLEDLFPTT 480

Query: 481 KIPNPRFQRLFQCLLHRALHPREPLPPIQQHIWNMLNPPAEVTTKSQIPLSKIKTLFPLI 540
           KIPNPRFQRLFQCLLHRALHPREPLPPIQQHIWNMLNPPAEVTTKSQIPLSKIKTLFPLI
Sbjct: 481 KIPNPRFQRLFQCLLHRALHPREPLPPIQQHIWNMLNPPAEVTTKSQIPLSKIKTLFPLI 540

Query: 541 EAKKKDQVTAQEIFQDNHEDGPTAKKLKTEQGGAHFSVSSLAEGSVTSVGSVNPAENFRV 600
           EAKKKDQVTAQEIFQDNHEDGPTAKKLKTEQGGAHFSVSSLAEGSVTSVGSVNPAENFRV
Sbjct: 541 EAKKKDQVTAQEIFQDNHEDGPTAKKLKTEQGGAHFSVSSLAEGSVTSVGSVNPAENFRV 600

Query: 601 LVKQKKASFEEASNQLINHIEQFLDTNETPYFMKSIDCIRAFREEAIKFSEEQRFNNFLK 660
           LVKQKKASFEEASNQLINHIEQFLDTNETPYFMKSIDCIRAFREEAIKFSEEQRFNNFLK
Sbjct: 601 LVKQKKASFEEASNQLINHIEQFLDTNETPYFMKSIDCIRAFREEAIKFSEEQRFNNFLK 660

Query: 661 ALQEKVEIKQLNHFWEIVVQDGITLITKEEASGSSVTAEEAKKFLAPKDKPSGDTAAVFE 720
           ALQEKVEIKQLNHFWEIVVQDGITLITKEEASGSSVTAEEAKKFLAPKDKPSGDTAAVFE
Sbjct: 661 ALQEKVEIKQLNHFWEIVVQDGITLITKEEASGSSVTAEEAKKFLAPKDKPSGDTAAVFE 720

Query: 721 EGGDVDDLLDMI 732
           EGGDVDDLLDMI
Sbjct: 721 EGGDVDDLLDMI 732


>gi|20127519 TPX2, microtubule-associated protein homolog [Homo
           sapiens]
          Length = 747

 Score = 34.3 bits (77), Expect = 0.42
 Identities = 23/104 (22%), Positives = 51/104 (49%), Gaps = 2/104 (1%)

Query: 589 VGSVNPAENFRVLVKQKKASFEEASNQLINHIEQFLDTNETPYFMKSIDCIRAFREEAIK 648
           +  + P++  +V   +KK   E +++Q  +  E+   + E      ++ C+   +++ +K
Sbjct: 151 IDEILPSKKMKVSNNKKKPEEEGSAHQ--DTAEKNASSPEKAKGRHTVPCMPPAKQKFLK 208

Query: 649 FSEEQRFNNFLKALQEKVEIKQLNHFWEIVVQDGITLITKEEAS 692
            +EEQ     +K  QE VE+++ N  ++ +   GI    K+  S
Sbjct: 209 STEEQELEKSMKMQQEVVEMRKKNEEFKKLALAGIGQPVKKSVS 252


>gi|118498368 kinectin 1 isoform c [Homo sapiens]
          Length = 1300

 Score = 32.3 bits (72), Expect = 1.6
 Identities = 52/268 (19%), Positives = 107/268 (39%), Gaps = 43/268 (16%)

Query: 465  KKDEKTDTLEDLFPTTKIPNPRFQRLFQCLLHRALHPREPLPPIQQHIWNMLNPPAEVTT 524
            +KD K  ++E+L     +     ++  Q L       +E +  +Q      L+  ++V  
Sbjct: 805  EKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQE 864

Query: 525  KSQIPLSK---IKTLFPLIEAKKKDQVTAQEIFQDNHEDGPTAKKLKTEQGGAHFSVSSL 581
               +   K   + T+  ++E K+KD     +  QD  E+  + K        AH  V  +
Sbjct: 865  LQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLK--------AH--VQEV 914

Query: 582  AEGSVTSVGSVNPAENFRVLVKQK-------KASFEEASNQLINHIEQFLDTNETPYFMK 634
            A+ ++    S +  E   +++K+K       +A  +E  + L +  +   D  +     K
Sbjct: 915  AQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFK 974

Query: 635  SIDCIRAFREEAIKFSEEQRFNNF------LKALQEKVEIKQLNHFWEIV--VQDGITLI 686
            S       + E +K    Q+ ++F      LK + E+   K+++  W  +  ++D +   
Sbjct: 975  S-------QIEQLKQQNYQQASSFPPHEELLKVISERE--KEISGLWNELDSLKDAVEHQ 1025

Query: 687  TK------EEASGSSVTAEEAKKFLAPK 708
             K      ++     + A+E  K L PK
Sbjct: 1026 RKKNNERQQQVEAVELEAKEVLKKLFPK 1053


>gi|156119605 general transcription factor IIIC 4 [Homo sapiens]
          Length = 822

 Score = 32.3 bits (72), Expect = 1.6
 Identities = 29/103 (28%), Positives = 51/103 (49%), Gaps = 14/103 (13%)

Query: 573 GAHFSVSSLAEGSVTSVGSVNPAENFRVLVKQKKASFEEASNQLINHIEQFLDTNETPYF 632
           GA+ ++ +  EG +  +  VN  +N++V     K +FEEA+ QL+    Q L        
Sbjct: 486 GAYLAIIT-TEGMINGLHPVN--KNYQVQFVTLK-TFEEAAAQLLESSVQNL-------- 533

Query: 633 MKSIDCIRAFREEAIKFSEEQRFNNFLKALQEKVEIKQLNHFW 675
            K +D I   R + +K     +F    +AL++K+E   + +FW
Sbjct: 534 FKQVDLIDLVRWKILKDKHIPQF--LQEALEKKIESSGVTYFW 574


>gi|153791300 SDA1 domain containing 1 [Homo sapiens]
          Length = 687

 Score = 32.3 bits (72), Expect = 1.6
 Identities = 33/136 (24%), Positives = 57/136 (41%), Gaps = 20/136 (14%)

Query: 509 QQHIWNMLNPPAEVTTKSQIPLSKIKTLFPLIEAKKKDQVTAQEIFQDNHEDGPTAKKLK 568
           +++IWN       +TT     ++KI  +  L     KD+   Q+   ++ +DGPTA+ L 
Sbjct: 189 RRNIWNDAKTVNVITTACFSKVTKI-LVAALTFFLGKDEDEKQDSDSESEDDGPTARDLL 247

Query: 569 TEQGGAHFSVSSLAEGSVTSVGSVNPAENFRVLVKQKKASFEEASN----QLINHIEQFL 624
            +           A G  +S       +  +VL KQKK    E  N     LI+  + F 
Sbjct: 248 VQ----------YATGKKSSKNKKKLEKAMKVLKKQKKKKKPEVFNFSAIHLIHDPQDFA 297

Query: 625 DTNETPYFMKSIDCIR 640
           +       +K ++C +
Sbjct: 298 EK-----LLKQLECCK 308


>gi|118498356 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 44/227 (19%), Positives = 91/227 (40%), Gaps = 35/227 (15%)

Query: 465  KKDEKTDTLEDLFPTTKIPNPRFQRLFQCLLHRALHPREPLPPIQQHIWNMLNPPAEVTT 524
            +KD K  ++E+L     +     ++  Q L       +E +  +Q      L+  ++V  
Sbjct: 805  EKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQE 864

Query: 525  KSQIPLSK---IKTLFPLIEAKKKDQVTAQEIFQDNHEDGPTAKKLKTEQGGAHFSVSSL 581
               +   K   + T+  ++E K+KD     +  QD  E+  + K        AH  V  +
Sbjct: 865  LQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLK--------AH--VQEV 914

Query: 582  AEGSVTSVGSVNPAENFRVLVKQK-------KASFEEASNQLINHIEQFLDTNETPYFMK 634
            A+ ++    S +  E   +++K+K       +A  +E  + L +  +   D  +     K
Sbjct: 915  AQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFK 974

Query: 635  SIDCIRAFREEAIKFSEEQRFNNF------LKALQEKVEIKQLNHFW 675
            S       + E +K    Q+ ++F      LK + E+   K+++  W
Sbjct: 975  S-------QIEQLKQQNYQQASSFPPHEELLKVISERE--KEISGLW 1012


>gi|33620775 kinectin 1 isoform a [Homo sapiens]
          Length = 1357

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 44/227 (19%), Positives = 91/227 (40%), Gaps = 35/227 (15%)

Query: 465  KKDEKTDTLEDLFPTTKIPNPRFQRLFQCLLHRALHPREPLPPIQQHIWNMLNPPAEVTT 524
            +KD K  ++E+L     +     ++  Q L       +E +  +Q      L+  ++V  
Sbjct: 805  EKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQE 864

Query: 525  KSQIPLSK---IKTLFPLIEAKKKDQVTAQEIFQDNHEDGPTAKKLKTEQGGAHFSVSSL 581
               +   K   + T+  ++E K+KD     +  QD  E+  + K        AH  V  +
Sbjct: 865  LQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLK--------AH--VQEV 914

Query: 582  AEGSVTSVGSVNPAENFRVLVKQK-------KASFEEASNQLINHIEQFLDTNETPYFMK 634
            A+ ++    S +  E   +++K+K       +A  +E  + L +  +   D  +     K
Sbjct: 915  AQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFK 974

Query: 635  SIDCIRAFREEAIKFSEEQRFNNF------LKALQEKVEIKQLNHFW 675
            S       + E +K    Q+ ++F      LK + E+   K+++  W
Sbjct: 975  S-------QIEQLKQQNYQQASSFPPHEELLKVISERE--KEISGLW 1012


>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
           sapiens]
          Length = 1483

 Score = 31.6 bits (70), Expect = 2.7
 Identities = 38/146 (26%), Positives = 65/146 (44%), Gaps = 22/146 (15%)

Query: 215 LEGEDGLDEIYSFSESLRKLCVFK-KIERHSIH-WPCRLTIGSNLSIRIAA--------- 263
           L GE+ L  I    E+ R    ++ ++ER+S   W C+ T  S L+ + A          
Sbjct: 16  LPGEEPLFTIPHTQEAFRTREEYEARLERYSERIWTCKSTGSSQLTHKEAWEEEQEVAEL 75

Query: 264 --------YKSILQERVKKTWTVVDAKTLKKEDIQKETVYCLNDDDETEVLKEDIIQGFR 315
                   Y+ ++ E V      ++ K +    ++  T Y + ++ + EV KE +++   
Sbjct: 76  LKEEFPAWYEKLVLEMVHHNTASLE-KLVDTAWLEIMTKYAVGEECDFEVGKEKMLKVKI 134

Query: 316 YGSDIVPFSKVDEEQMKYKSEGKCFS 341
               I P  KVDEE  + KS+G C S
Sbjct: 135 V--KIHPLEKVDEEATEKKSDGACDS 158


>gi|223468617 family with sequence similarity 75, member C1 [Homo
            sapiens]
          Length = 1188

 Score = 31.2 bits (69), Expect = 3.6
 Identities = 17/53 (32%), Positives = 29/53 (54%)

Query: 650  SEEQRFNNFLKALQEKVEIKQLNHFWEIVVQDGITLITKEEASGSSVTAEEAK 702
            +E+ R N  ++ L  K +   ++HF E + Q   T+ +K+E   + VTAE  K
Sbjct: 991  TEDTRQNEGVQLLPSKKQPPSISHFGENIKQFFETIFSKKERKPAPVTAESQK 1043


>gi|54633319 PDZ domain-containing guanine nucleotide exchange factor
            I [Homo sapiens]
          Length = 1601

 Score = 30.8 bits (68), Expect = 4.7
 Identities = 38/181 (20%), Positives = 75/181 (41%), Gaps = 9/181 (4%)

Query: 223  EIYSFSESLRKLCVFKKIERHSIHWPCRLTIGSNLSIRIAAYKSILQ-ERVKKTWTVVDA 281
            EI + +  L+++ + K   + ++H  CR     N    I +  ++    R++ TW  + +
Sbjct: 917  EILTEANQLKRMKIIKHFIKIALH--CRECKNFNSMFAIISGLNLASVARLRGTWEKLPS 974

Query: 282  KTLKK-EDIQKETVYCLNDDDETEVLKEDIIQGFRYGSDIVPFSKVDEEQMKYKSEGKCF 340
            K  K  +D+Q      + D         +I+        I+P   V ++ M +  EG   
Sbjct: 975  KYEKHLQDLQD-----IFDPSRNMAKYRNILSSQSMQPPIIPLFPVVKKDMTFLHEGNDS 1029

Query: 341  SVLGFCKSSQVQRRFFMGNQVLKVFAARDDEAAAVALSSLIHALDDLDMVAIVRYAYDKR 400
             V G     +++       QV+++ +A  D A      SL     + +M+ +   A+ KR
Sbjct: 1030 KVDGLVNFEKLRMISKEIRQVVRMTSANMDPAMMFRQRSLSQGSTNSNMLDVQGGAHKKR 1089

Query: 401  A 401
            A
Sbjct: 1090 A 1090


>gi|57165355 latrophilin 1 isoform 1 precursor [Homo sapiens]
          Length = 1474

 Score = 30.4 bits (67), Expect = 6.1
 Identities = 13/39 (33%), Positives = 22/39 (56%)

Query: 93  DIESKIQPGSQQADFLDALIVSMDVIQHETIGKKFEKRH 131
           D+ S ++   Q  D LDA + ++  I+ E+ GK + K H
Sbjct: 569 DVSSSVKLMEQLLDILDAQLQALRPIERESAGKNYNKMH 607


>gi|41281557 latrophilin 1 isoform 2 precursor [Homo sapiens]
          Length = 1469

 Score = 30.4 bits (67), Expect = 6.1
 Identities = 13/39 (33%), Positives = 22/39 (56%)

Query: 93  DIESKIQPGSQQADFLDALIVSMDVIQHETIGKKFEKRH 131
           D+ S ++   Q  D LDA + ++  I+ E+ GK + K H
Sbjct: 564 DVSSSVKLMEQLLDILDAQLQALRPIERESAGKNYNKMH 602


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,550,165
Number of Sequences: 37866
Number of extensions: 1192416
Number of successful extensions: 3017
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 3009
Number of HSP's gapped (non-prelim): 21
length of query: 732
length of database: 18,247,518
effective HSP length: 110
effective length of query: 622
effective length of database: 14,082,258
effective search space: 8759164476
effective search space used: 8759164476
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.