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Search of human proteins with 10862701
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|10862701 ret proto-oncogene isoform c [Homo sapiens]
(1072 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|10862701 ret proto-oncogene isoform c [Homo sapiens] 2188 0.0
gi|10862703 ret proto-oncogene isoform a [Homo sapiens] 2170 0.0
gi|222144241 fibroblast growth factor receptor 2 isoform 8 precu... 330 4e-90
gi|222144239 fibroblast growth factor receptor 2 isoform 7 precu... 329 7e-90
gi|222144237 fibroblast growth factor receptor 2 isoform 6 precu... 329 7e-90
gi|222144233 fibroblast growth factor receptor 2 isoform 4 precu... 329 7e-90
gi|221316639 fibroblast growth factor receptor 2 isoform 1 precu... 329 7e-90
gi|221316638 fibroblast growth factor receptor 2 isoform 2 precu... 329 7e-90
gi|254028242 fibroblast growth factor receptor 3 isoform 3 precu... 328 2e-89
gi|13112048 fibroblast growth factor receptor 3 isoform 2 precur... 328 2e-89
gi|4503711 fibroblast growth factor receptor 3 isoform 1 precurs... 328 2e-89
gi|13186236 fibroblast growth factor receptor 1 isoform 4 precur... 328 2e-89
gi|13186234 fibroblast growth factor receptor 1 isoform 3 precur... 328 2e-89
gi|13186251 fibroblast growth factor receptor 1 isoform 2 precur... 328 2e-89
gi|105990522 fibroblast growth factor receptor 1 isoform 1 precu... 328 2e-89
gi|222144244 fibroblast growth factor receptor 2 isoform 9 precu... 324 3e-88
gi|222144231 fibroblast growth factor receptor 2 isoform 3 precu... 324 3e-88
gi|222144235 fibroblast growth factor receptor 2 isoform 5 precu... 324 3e-88
gi|47524175 fibroblast growth factor receptor 4 isoform 1 precur... 321 2e-87
gi|47524173 fibroblast growth factor receptor 4 isoform 1 precur... 321 2e-87
gi|47524177 fibroblast growth factor receptor 4 isoform 2 precur... 320 5e-87
gi|11321597 kinase insert domain receptor precursor [Homo sapiens] 274 4e-73
gi|13186249 fibroblast growth factor receptor 1 isoform 9 precur... 273 5e-73
gi|4885631 tyrosine kinase with immunoglobulin-like and EGF-like... 259 7e-69
gi|88758596 TEK tyrosine kinase, endothelial precursor [Homo sap... 244 4e-64
gi|19924165 proto-oncogene c-ros-1 protein precursor [Homo sapiens] 234 4e-61
gi|5031927 skeletal muscle receptor tyrosine kinase [Homo sapiens] 230 5e-60
gi|4557665 insulin-like growth factor 1 receptor precursor [Homo... 223 1e-57
gi|31657140 insulin receptor-related receptor precursor [Homo sa... 221 3e-57
gi|119395738 insulin receptor isoform Short precursor [Homo sapi... 220 6e-57
>gi|10862701 ret proto-oncogene isoform c [Homo sapiens]
Length = 1072
Score = 2188 bits (5670), Expect = 0.0
Identities = 1072/1072 (100%), Positives = 1072/1072 (100%)
Query: 1 MAKATSGAAGLRLLLLLLLPLLGKVALGLYFSRDAYWEKLYVDQAAGTPLLYVHALRDAP 60
MAKATSGAAGLRLLLLLLLPLLGKVALGLYFSRDAYWEKLYVDQAAGTPLLYVHALRDAP
Sbjct: 1 MAKATSGAAGLRLLLLLLLPLLGKVALGLYFSRDAYWEKLYVDQAAGTPLLYVHALRDAP 60
Query: 61 EEVPSFRLGQHLYGTYRTRLHENNWICIQEDTGLLYLNRSLDHSSWEKLSVRNRGFPLLT 120
EEVPSFRLGQHLYGTYRTRLHENNWICIQEDTGLLYLNRSLDHSSWEKLSVRNRGFPLLT
Sbjct: 61 EEVPSFRLGQHLYGTYRTRLHENNWICIQEDTGLLYLNRSLDHSSWEKLSVRNRGFPLLT 120
Query: 121 VYLKVFLSPTSLREGECQWPGCARVYFSFFNTSFPACSSLKPRELCFPETRPSFRIRENR 180
VYLKVFLSPTSLREGECQWPGCARVYFSFFNTSFPACSSLKPRELCFPETRPSFRIRENR
Sbjct: 121 VYLKVFLSPTSLREGECQWPGCARVYFSFFNTSFPACSSLKPRELCFPETRPSFRIRENR 180
Query: 181 PPGTFHQFRLLPVQFLCPNISVAYRLLEGEGLPFRCAPDSLEVSTRWALDREQREKYELV 240
PPGTFHQFRLLPVQFLCPNISVAYRLLEGEGLPFRCAPDSLEVSTRWALDREQREKYELV
Sbjct: 181 PPGTFHQFRLLPVQFLCPNISVAYRLLEGEGLPFRCAPDSLEVSTRWALDREQREKYELV 240
Query: 241 AVCTVHAGAREEVVMVPFPVTVYDEDDSAPTFPAGVDTASAVVEFKRKEDTVVATLRVFD 300
AVCTVHAGAREEVVMVPFPVTVYDEDDSAPTFPAGVDTASAVVEFKRKEDTVVATLRVFD
Sbjct: 241 AVCTVHAGAREEVVMVPFPVTVYDEDDSAPTFPAGVDTASAVVEFKRKEDTVVATLRVFD 300
Query: 301 ADVVPASGELVRRYTSTLLPGDTWAQQTFRVEHWPNETSVQANGSFVRATVHDYRLVLNR 360
ADVVPASGELVRRYTSTLLPGDTWAQQTFRVEHWPNETSVQANGSFVRATVHDYRLVLNR
Sbjct: 301 ADVVPASGELVRRYTSTLLPGDTWAQQTFRVEHWPNETSVQANGSFVRATVHDYRLVLNR 360
Query: 361 NLSISENRTMQLAVLVNDSDFQGPGAGVLLLHFNVSVLPVSLHLPSTYSLSVSRRARRFA 420
NLSISENRTMQLAVLVNDSDFQGPGAGVLLLHFNVSVLPVSLHLPSTYSLSVSRRARRFA
Sbjct: 361 NLSISENRTMQLAVLVNDSDFQGPGAGVLLLHFNVSVLPVSLHLPSTYSLSVSRRARRFA 420
Query: 421 QIGKVCVENCQAFSGINVQYKLHSSGANCSTLGVVTSAEDTSGILFVNDTKALRRPKCAE 480
QIGKVCVENCQAFSGINVQYKLHSSGANCSTLGVVTSAEDTSGILFVNDTKALRRPKCAE
Sbjct: 421 QIGKVCVENCQAFSGINVQYKLHSSGANCSTLGVVTSAEDTSGILFVNDTKALRRPKCAE 480
Query: 481 LHYMVVATDQQTSRQAQAQLLVTVEGSYVAEEAGCPLSCAVSKRRLECEECGGLGSPTGR 540
LHYMVVATDQQTSRQAQAQLLVTVEGSYVAEEAGCPLSCAVSKRRLECEECGGLGSPTGR
Sbjct: 481 LHYMVVATDQQTSRQAQAQLLVTVEGSYVAEEAGCPLSCAVSKRRLECEECGGLGSPTGR 540
Query: 541 CEWRQGDGKGITRNFSTCSPSTKTCPDGHCDVVETQDINICPQDCLRGSIVGGHEPGEPR 600
CEWRQGDGKGITRNFSTCSPSTKTCPDGHCDVVETQDINICPQDCLRGSIVGGHEPGEPR
Sbjct: 541 CEWRQGDGKGITRNFSTCSPSTKTCPDGHCDVVETQDINICPQDCLRGSIVGGHEPGEPR 600
Query: 601 GIKAGYGTCNCFPEEEKCFCEPEDIQDPLCDELCRTVIAAAVLFSFIVSVLLSAFCIHCY 660
GIKAGYGTCNCFPEEEKCFCEPEDIQDPLCDELCRTVIAAAVLFSFIVSVLLSAFCIHCY
Sbjct: 601 GIKAGYGTCNCFPEEEKCFCEPEDIQDPLCDELCRTVIAAAVLFSFIVSVLLSAFCIHCY 660
Query: 661 HKFAHKPPISSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFP 720
HKFAHKPPISSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFP
Sbjct: 661 HKFAHKPPISSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFP 720
Query: 721 RKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLK 780
RKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLK
Sbjct: 721 RKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLK 780
Query: 781 QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDH 840
QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDH
Sbjct: 781 QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDH 840
Query: 841 PDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVY 900
PDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVY
Sbjct: 841 PDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVY 900
Query: 901 EEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERL 960
EEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERL
Sbjct: 901 EEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERL 960
Query: 961 FNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAA 1020
FNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAA
Sbjct: 961 FNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAA 1020
Query: 1021 STPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGRISHAFTRF 1072
STPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGRISHAFTRF
Sbjct: 1021 STPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGRISHAFTRF 1072
>gi|10862703 ret proto-oncogene isoform a [Homo sapiens]
Length = 1114
Score = 2170 bits (5623), Expect = 0.0
Identities = 1063/1063 (100%), Positives = 1063/1063 (100%)
Query: 1 MAKATSGAAGLRLLLLLLLPLLGKVALGLYFSRDAYWEKLYVDQAAGTPLLYVHALRDAP 60
MAKATSGAAGLRLLLLLLLPLLGKVALGLYFSRDAYWEKLYVDQAAGTPLLYVHALRDAP
Sbjct: 1 MAKATSGAAGLRLLLLLLLPLLGKVALGLYFSRDAYWEKLYVDQAAGTPLLYVHALRDAP 60
Query: 61 EEVPSFRLGQHLYGTYRTRLHENNWICIQEDTGLLYLNRSLDHSSWEKLSVRNRGFPLLT 120
EEVPSFRLGQHLYGTYRTRLHENNWICIQEDTGLLYLNRSLDHSSWEKLSVRNRGFPLLT
Sbjct: 61 EEVPSFRLGQHLYGTYRTRLHENNWICIQEDTGLLYLNRSLDHSSWEKLSVRNRGFPLLT 120
Query: 121 VYLKVFLSPTSLREGECQWPGCARVYFSFFNTSFPACSSLKPRELCFPETRPSFRIRENR 180
VYLKVFLSPTSLREGECQWPGCARVYFSFFNTSFPACSSLKPRELCFPETRPSFRIRENR
Sbjct: 121 VYLKVFLSPTSLREGECQWPGCARVYFSFFNTSFPACSSLKPRELCFPETRPSFRIRENR 180
Query: 181 PPGTFHQFRLLPVQFLCPNISVAYRLLEGEGLPFRCAPDSLEVSTRWALDREQREKYELV 240
PPGTFHQFRLLPVQFLCPNISVAYRLLEGEGLPFRCAPDSLEVSTRWALDREQREKYELV
Sbjct: 181 PPGTFHQFRLLPVQFLCPNISVAYRLLEGEGLPFRCAPDSLEVSTRWALDREQREKYELV 240
Query: 241 AVCTVHAGAREEVVMVPFPVTVYDEDDSAPTFPAGVDTASAVVEFKRKEDTVVATLRVFD 300
AVCTVHAGAREEVVMVPFPVTVYDEDDSAPTFPAGVDTASAVVEFKRKEDTVVATLRVFD
Sbjct: 241 AVCTVHAGAREEVVMVPFPVTVYDEDDSAPTFPAGVDTASAVVEFKRKEDTVVATLRVFD 300
Query: 301 ADVVPASGELVRRYTSTLLPGDTWAQQTFRVEHWPNETSVQANGSFVRATVHDYRLVLNR 360
ADVVPASGELVRRYTSTLLPGDTWAQQTFRVEHWPNETSVQANGSFVRATVHDYRLVLNR
Sbjct: 301 ADVVPASGELVRRYTSTLLPGDTWAQQTFRVEHWPNETSVQANGSFVRATVHDYRLVLNR 360
Query: 361 NLSISENRTMQLAVLVNDSDFQGPGAGVLLLHFNVSVLPVSLHLPSTYSLSVSRRARRFA 420
NLSISENRTMQLAVLVNDSDFQGPGAGVLLLHFNVSVLPVSLHLPSTYSLSVSRRARRFA
Sbjct: 361 NLSISENRTMQLAVLVNDSDFQGPGAGVLLLHFNVSVLPVSLHLPSTYSLSVSRRARRFA 420
Query: 421 QIGKVCVENCQAFSGINVQYKLHSSGANCSTLGVVTSAEDTSGILFVNDTKALRRPKCAE 480
QIGKVCVENCQAFSGINVQYKLHSSGANCSTLGVVTSAEDTSGILFVNDTKALRRPKCAE
Sbjct: 421 QIGKVCVENCQAFSGINVQYKLHSSGANCSTLGVVTSAEDTSGILFVNDTKALRRPKCAE 480
Query: 481 LHYMVVATDQQTSRQAQAQLLVTVEGSYVAEEAGCPLSCAVSKRRLECEECGGLGSPTGR 540
LHYMVVATDQQTSRQAQAQLLVTVEGSYVAEEAGCPLSCAVSKRRLECEECGGLGSPTGR
Sbjct: 481 LHYMVVATDQQTSRQAQAQLLVTVEGSYVAEEAGCPLSCAVSKRRLECEECGGLGSPTGR 540
Query: 541 CEWRQGDGKGITRNFSTCSPSTKTCPDGHCDVVETQDINICPQDCLRGSIVGGHEPGEPR 600
CEWRQGDGKGITRNFSTCSPSTKTCPDGHCDVVETQDINICPQDCLRGSIVGGHEPGEPR
Sbjct: 541 CEWRQGDGKGITRNFSTCSPSTKTCPDGHCDVVETQDINICPQDCLRGSIVGGHEPGEPR 600
Query: 601 GIKAGYGTCNCFPEEEKCFCEPEDIQDPLCDELCRTVIAAAVLFSFIVSVLLSAFCIHCY 660
GIKAGYGTCNCFPEEEKCFCEPEDIQDPLCDELCRTVIAAAVLFSFIVSVLLSAFCIHCY
Sbjct: 601 GIKAGYGTCNCFPEEEKCFCEPEDIQDPLCDELCRTVIAAAVLFSFIVSVLLSAFCIHCY 660
Query: 661 HKFAHKPPISSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFP 720
HKFAHKPPISSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFP
Sbjct: 661 HKFAHKPPISSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFP 720
Query: 721 RKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLK 780
RKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLK
Sbjct: 721 RKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLK 780
Query: 781 QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDH 840
QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDH
Sbjct: 781 QVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDH 840
Query: 841 PDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVY 900
PDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVY
Sbjct: 841 PDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVY 900
Query: 901 EEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERL 960
EEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERL
Sbjct: 901 EEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERL 960
Query: 961 FNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAA 1020
FNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAA
Sbjct: 961 FNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAA 1020
Query: 1021 STPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYG 1063
STPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYG
Sbjct: 1021 STPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYG 1063
>gi|222144241 fibroblast growth factor receptor 2 isoform 8 precursor
[Homo sapiens]
Length = 704
Score = 330 bits (846), Expect = 4e-90
Identities = 180/384 (46%), Positives = 238/384 (61%), Gaps = 29/384 (7%)
Query: 661 HKFAHKPPI-------SSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILE 713
HK + P+ SS+ M P SS+ A P L V +++ E
Sbjct: 301 HKLTKRIPLRRQVSAESSSSMNSNTPLVRITTRLSST-ADTPML------AGVSEYELPE 353
Query: 714 DPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHL---KGRAGYTTVAVKMLKENASPSELR 770
DPKWEFPR L LGK LGEG FG+VV A A + K + TVAVKMLK++A+ +L
Sbjct: 354 DPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKDKPKEA-VTVAVKMLKDDATEKDLS 412
Query: 771 DLLSEFNVLKQVN-HPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGS 829
DL+SE ++K + H ++I L GAC+QDGPL +IVEYA G+LR +LR R G Y
Sbjct: 413 DLVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEY--- 469
Query: 830 GGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMK 889
S ++ E +T DL+S +Q+++GM+YLA K +HRDLAARN+LV E MK
Sbjct: 470 -----SYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMK 524
Query: 890 ISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGG 949
I+DFGL+RD+ D Y K + GR+PVKWMA E+LFD +YT QSDVWSFGVL+WEI TLGG
Sbjct: 525 IADFGLARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGG 584
Query: 950 NPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKM- 1008
+PYPGIP E LF LLK GHRM++P NC+ E+Y +M CW P +RP F + +DL+++
Sbjct: 585 SPYPGIPVEELFKLLKEGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIL 644
Query: 1009 -MVKRRDYLDLAASTPSDSLIYDD 1031
+ +YLDL+ S Y D
Sbjct: 645 TLTTNEEYLDLSQPLEQYSPSYPD 668
>gi|222144239 fibroblast growth factor receptor 2 isoform 7 precursor
[Homo sapiens]
Length = 705
Score = 329 bits (844), Expect = 7e-90
Identities = 177/368 (48%), Positives = 233/368 (63%), Gaps = 22/368 (5%)
Query: 670 SSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFPRKNLVLGKT 729
SS+ M P SS+ A P L V +++ EDPKWEFPR L LGK
Sbjct: 318 SSSSMNSNTPLVRITTRLSST-ADTPML------AGVSEYELPEDPKWEFPRDKLTLGKP 370
Query: 730 LGEGEFGKVVKATAFHL---KGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVN-HP 785
LGEG FG+VV A A + K + TVAVKMLK++A+ +L DL+SE ++K + H
Sbjct: 371 LGEGCFGQVVMAEAVGIDKDKPKEA-VTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHK 429
Query: 786 HVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERA 845
++I L GAC+QDGPL +IVEYA G+LR +LR R G Y S ++ E
Sbjct: 430 NIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEY--------SYDINRVPEEQ 481
Query: 846 LTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSY 905
+T DL+S +Q+++GM+YLA K +HRDLAARN+LV E MKI+DFGL+RD+ D Y
Sbjct: 482 MTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYY 541
Query: 906 VKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLK 965
K + GR+PVKWMA E+LFD +YT QSDVWSFGVL+WEI TLGG+PYPGIP E LF LLK
Sbjct: 542 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 601
Query: 966 TGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKM--MVKRRDYLDLAASTP 1023
GHRM++P NC+ E+Y +M CW P +RP F + +DL+++ + +YLDL+
Sbjct: 602 EGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLE 661
Query: 1024 SDSLIYDD 1031
S Y D
Sbjct: 662 QYSPSYPD 669
>gi|222144237 fibroblast growth factor receptor 2 isoform 6 precursor
[Homo sapiens]
Length = 706
Score = 329 bits (844), Expect = 7e-90
Identities = 177/368 (48%), Positives = 233/368 (63%), Gaps = 22/368 (5%)
Query: 670 SSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFPRKNLVLGKT 729
SS+ M P SS+ A P L V +++ EDPKWEFPR L LGK
Sbjct: 319 SSSSMNSNTPLVRITTRLSST-ADTPML------AGVSEYELPEDPKWEFPRDKLTLGKP 371
Query: 730 LGEGEFGKVVKATAFHL---KGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVN-HP 785
LGEG FG+VV A A + K + TVAVKMLK++A+ +L DL+SE ++K + H
Sbjct: 372 LGEGCFGQVVMAEAVGIDKDKPKEA-VTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHK 430
Query: 786 HVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERA 845
++I L GAC+QDGPL +IVEYA G+LR +LR R G Y S ++ E
Sbjct: 431 NIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEY--------SYDINRVPEEQ 482
Query: 846 LTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSY 905
+T DL+S +Q+++GM+YLA K +HRDLAARN+LV E MKI+DFGL+RD+ D Y
Sbjct: 483 MTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYY 542
Query: 906 VKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLK 965
K + GR+PVKWMA E+LFD +YT QSDVWSFGVL+WEI TLGG+PYPGIP E LF LLK
Sbjct: 543 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 602
Query: 966 TGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKM--MVKRRDYLDLAASTP 1023
GHRM++P NC+ E+Y +M CW P +RP F + +DL+++ + +YLDL+
Sbjct: 603 EGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLE 662
Query: 1024 SDSLIYDD 1031
S Y D
Sbjct: 663 QYSPSYPD 670
>gi|222144233 fibroblast growth factor receptor 2 isoform 4 precursor
[Homo sapiens]
Length = 709
Score = 329 bits (844), Expect = 7e-90
Identities = 177/368 (48%), Positives = 233/368 (63%), Gaps = 22/368 (5%)
Query: 670 SSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFPRKNLVLGKT 729
SS+ M P SS+ A P L V +++ EDPKWEFPR L LGK
Sbjct: 322 SSSSMNSNTPLVRITTRLSST-ADTPML------AGVSEYELPEDPKWEFPRDKLTLGKP 374
Query: 730 LGEGEFGKVVKATAFHL---KGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVN-HP 785
LGEG FG+VV A A + K + TVAVKMLK++A+ +L DL+SE ++K + H
Sbjct: 375 LGEGCFGQVVMAEAVGIDKDKPKEA-VTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHK 433
Query: 786 HVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERA 845
++I L GAC+QDGPL +IVEYA G+LR +LR R G Y S ++ E
Sbjct: 434 NIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEY--------SYDINRVPEEQ 485
Query: 846 LTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSY 905
+T DL+S +Q+++GM+YLA K +HRDLAARN+LV E MKI+DFGL+RD+ D Y
Sbjct: 486 MTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYY 545
Query: 906 VKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLK 965
K + GR+PVKWMA E+LFD +YT QSDVWSFGVL+WEI TLGG+PYPGIP E LF LLK
Sbjct: 546 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 605
Query: 966 TGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKM--MVKRRDYLDLAASTP 1023
GHRM++P NC+ E+Y +M CW P +RP F + +DL+++ + +YLDL+
Sbjct: 606 EGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLE 665
Query: 1024 SDSLIYDD 1031
S Y D
Sbjct: 666 QYSPSYPD 673
>gi|221316639 fibroblast growth factor receptor 2 isoform 1 precursor
[Homo sapiens]
Length = 821
Score = 329 bits (844), Expect = 7e-90
Identities = 177/368 (48%), Positives = 233/368 (63%), Gaps = 22/368 (5%)
Query: 670 SSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFPRKNLVLGKT 729
SS+ M P SS+ A P L V +++ EDPKWEFPR L LGK
Sbjct: 434 SSSSMNSNTPLVRITTRLSST-ADTPML------AGVSEYELPEDPKWEFPRDKLTLGKP 486
Query: 730 LGEGEFGKVVKATAFHL---KGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVN-HP 785
LGEG FG+VV A A + K + TVAVKMLK++A+ +L DL+SE ++K + H
Sbjct: 487 LGEGCFGQVVMAEAVGIDKDKPKEA-VTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHK 545
Query: 786 HVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERA 845
++I L GAC+QDGPL +IVEYA G+LR +LR R G Y S ++ E
Sbjct: 546 NIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEY--------SYDINRVPEEQ 597
Query: 846 LTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSY 905
+T DL+S +Q+++GM+YLA K +HRDLAARN+LV E MKI+DFGL+RD+ D Y
Sbjct: 598 MTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYY 657
Query: 906 VKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLK 965
K + GR+PVKWMA E+LFD +YT QSDVWSFGVL+WEI TLGG+PYPGIP E LF LLK
Sbjct: 658 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 717
Query: 966 TGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKM--MVKRRDYLDLAASTP 1023
GHRM++P NC+ E+Y +M CW P +RP F + +DL+++ + +YLDL+
Sbjct: 718 EGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLE 777
Query: 1024 SDSLIYDD 1031
S Y D
Sbjct: 778 QYSPSYPD 785
>gi|221316638 fibroblast growth factor receptor 2 isoform 2 precursor
[Homo sapiens]
Length = 822
Score = 329 bits (844), Expect = 7e-90
Identities = 177/368 (48%), Positives = 233/368 (63%), Gaps = 22/368 (5%)
Query: 670 SSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFPRKNLVLGKT 729
SS+ M P SS+ A P L V +++ EDPKWEFPR L LGK
Sbjct: 435 SSSSMNSNTPLVRITTRLSST-ADTPML------AGVSEYELPEDPKWEFPRDKLTLGKP 487
Query: 730 LGEGEFGKVVKATAFHL---KGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVN-HP 785
LGEG FG+VV A A + K + TVAVKMLK++A+ +L DL+SE ++K + H
Sbjct: 488 LGEGCFGQVVMAEAVGIDKDKPKEA-VTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHK 546
Query: 786 HVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERA 845
++I L GAC+QDGPL +IVEYA G+LR +LR R G Y S ++ E
Sbjct: 547 NIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEY--------SYDINRVPEEQ 598
Query: 846 LTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSY 905
+T DL+S +Q+++GM+YLA K +HRDLAARN+LV E MKI+DFGL+RD+ D Y
Sbjct: 599 MTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYY 658
Query: 906 VKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLK 965
K + GR+PVKWMA E+LFD +YT QSDVWSFGVL+WEI TLGG+PYPGIP E LF LLK
Sbjct: 659 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 718
Query: 966 TGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKM--MVKRRDYLDLAASTP 1023
GHRM++P NC+ E+Y +M CW P +RP F + +DL+++ + +YLDL+
Sbjct: 719 EGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLTTNEEYLDLSQPLE 778
Query: 1024 SDSLIYDD 1031
S Y D
Sbjct: 779 QYSPSYPD 786
>gi|254028242 fibroblast growth factor receptor 3 isoform 3 precursor
[Homo sapiens]
Length = 808
Score = 328 bits (840), Expect = 2e-89
Identities = 174/344 (50%), Positives = 226/344 (65%), Gaps = 23/344 (6%)
Query: 705 SVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHL-KGRAGY-TTVAVKMLKE 762
+V ++ DPKWE R L LGK LGEG FG+VV A A + K RA TVAVKMLK+
Sbjct: 455 NVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKD 514
Query: 763 NASPSELRDLLSEFNVLKQVN-HPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRK 821
+A+ +L DL+SE ++K + H ++I L GAC+Q GPL ++VEYA G+LR FLR R
Sbjct: 515 DATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRP 574
Query: 822 VGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNIL 881
G Y S P E LT DL+S A+Q+++GM+YLA K +HRDLAARN+L
Sbjct: 575 PGLDY--------SFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVL 626
Query: 882 VAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLL 941
V E MKI+DFGL+RDV+ D Y K + GR+PVKWMA E+LFD +YT QSDVWSFGVLL
Sbjct: 627 VTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLL 686
Query: 942 WEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADI 1001
WEI TLGG+PYPGIP E LF LLK GHRM++P NC+ ++Y +M +CW P +RP F +
Sbjct: 687 WEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQL 746
Query: 1002 SKDLEKMM--VKRRDYLDLAA----------STPSDSLIYDDGL 1033
+DL++++ +YLDL+A TPS S DD +
Sbjct: 747 VEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSV 790
>gi|13112048 fibroblast growth factor receptor 3 isoform 2 precursor
[Homo sapiens]
Length = 694
Score = 328 bits (840), Expect = 2e-89
Identities = 174/344 (50%), Positives = 226/344 (65%), Gaps = 23/344 (6%)
Query: 705 SVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHL-KGRAGY-TTVAVKMLKE 762
+V ++ DPKWE R L LGK LGEG FG+VV A A + K RA TVAVKMLK+
Sbjct: 341 NVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKD 400
Query: 763 NASPSELRDLLSEFNVLKQVN-HPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRK 821
+A+ +L DL+SE ++K + H ++I L GAC+Q GPL ++VEYA G+LR FLR R
Sbjct: 401 DATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRP 460
Query: 822 VGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNIL 881
G Y S P E LT DL+S A+Q+++GM+YLA K +HRDLAARN+L
Sbjct: 461 PGLDY--------SFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVL 512
Query: 882 VAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLL 941
V E MKI+DFGL+RDV+ D Y K + GR+PVKWMA E+LFD +YT QSDVWSFGVLL
Sbjct: 513 VTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLL 572
Query: 942 WEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADI 1001
WEI TLGG+PYPGIP E LF LLK GHRM++P NC+ ++Y +M +CW P +RP F +
Sbjct: 573 WEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQL 632
Query: 1002 SKDLEKMM--VKRRDYLDLAA----------STPSDSLIYDDGL 1033
+DL++++ +YLDL+A TPS S DD +
Sbjct: 633 VEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSV 676
>gi|4503711 fibroblast growth factor receptor 3 isoform 1 precursor
[Homo sapiens]
Length = 806
Score = 328 bits (840), Expect = 2e-89
Identities = 174/344 (50%), Positives = 226/344 (65%), Gaps = 23/344 (6%)
Query: 705 SVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHL-KGRAGY-TTVAVKMLKE 762
+V ++ DPKWE R L LGK LGEG FG+VV A A + K RA TVAVKMLK+
Sbjct: 453 NVSELELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKD 512
Query: 763 NASPSELRDLLSEFNVLKQVN-HPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRK 821
+A+ +L DL+SE ++K + H ++I L GAC+Q GPL ++VEYA G+LR FLR R
Sbjct: 513 DATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRP 572
Query: 822 VGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNIL 881
G Y S P E LT DL+S A+Q+++GM+YLA K +HRDLAARN+L
Sbjct: 573 PGLDY--------SFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVL 624
Query: 882 VAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLL 941
V E MKI+DFGL+RDV+ D Y K + GR+PVKWMA E+LFD +YT QSDVWSFGVLL
Sbjct: 625 VTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLL 684
Query: 942 WEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADI 1001
WEI TLGG+PYPGIP E LF LLK GHRM++P NC+ ++Y +M +CW P +RP F +
Sbjct: 685 WEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQL 744
Query: 1002 SKDLEKMM--VKRRDYLDLAA----------STPSDSLIYDDGL 1033
+DL++++ +YLDL+A TPS S DD +
Sbjct: 745 VEDLDRVLTVTSTDEYLDLSAPFEQYSPGGQDTPSSSSSGDDSV 788
>gi|13186236 fibroblast growth factor receptor 1 isoform 4 precursor
[Homo sapiens]
Length = 731
Score = 328 bits (840), Expect = 2e-89
Identities = 181/396 (45%), Positives = 248/396 (62%), Gaps = 30/396 (7%)
Query: 645 SFIVSVLLSAFCIHCYHKFAHKPPISSAEMTFRRPAQAFP------VSYSSSGAR----- 693
+F++S ++ + ++ K S +M + A++ P VS SS +
Sbjct: 293 AFLISCMVGSVIVYKMKSGTKKSDFHS-QMAVHKLAKSIPLRRQVTVSADSSASMNSGVL 351
Query: 694 --RPSLDSMENQ---VSVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHL-K 747
RPS S V +++ EDP+WE PR LVLGK LGEG FG+VV A A L K
Sbjct: 352 LVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDK 411
Query: 748 GRAGYTT-VAVKMLKENASPSELRDLLSEFNVLKQVN-HPHVIKLYGACSQDGPLLLIVE 805
+ T VAVKMLK +A+ +L DL+SE ++K + H ++I L GAC+QDGPL +IVE
Sbjct: 412 DKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVE 471
Query: 806 YAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYL 865
YA G+LR +L+ R G Y + H E L+ DL+S A+Q+++GM+YL
Sbjct: 472 YASKGNLREYLQARRPPGLEYCYNPS--------HNPEEQLSSKDLVSCAYQVARGMEYL 523
Query: 866 AEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFD 925
A K +HRDLAARN+LV E MKI+DFGL+RD++ D Y K + GR+PVKWMA E+LFD
Sbjct: 524 ASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFD 583
Query: 926 HIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLML 985
IYT QSDVWSFGVLLWEI TLGG+PYPG+P E LF LLK GHRM++P NC+ E+Y +M
Sbjct: 584 RIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMR 643
Query: 986 QCWKQEPDKRPVFADISKDLEKM--MVKRRDYLDLA 1019
CW P +RP F + +DL+++ + ++YLDL+
Sbjct: 644 DCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLS 679
>gi|13186234 fibroblast growth factor receptor 1 isoform 3 precursor
[Homo sapiens]
Length = 733
Score = 328 bits (840), Expect = 2e-89
Identities = 181/396 (45%), Positives = 248/396 (62%), Gaps = 30/396 (7%)
Query: 645 SFIVSVLLSAFCIHCYHKFAHKPPISSAEMTFRRPAQAFP------VSYSSSGAR----- 693
+F++S ++ + ++ K S +M + A++ P VS SS +
Sbjct: 295 AFLISCMVGSVIVYKMKSGTKKSDFHS-QMAVHKLAKSIPLRRQVTVSADSSASMNSGVL 353
Query: 694 --RPSLDSMENQ---VSVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHL-K 747
RPS S V +++ EDP+WE PR LVLGK LGEG FG+VV A A L K
Sbjct: 354 LVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDK 413
Query: 748 GRAGYTT-VAVKMLKENASPSELRDLLSEFNVLKQVN-HPHVIKLYGACSQDGPLLLIVE 805
+ T VAVKMLK +A+ +L DL+SE ++K + H ++I L GAC+QDGPL +IVE
Sbjct: 414 DKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVE 473
Query: 806 YAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYL 865
YA G+LR +L+ R G Y + H E L+ DL+S A+Q+++GM+YL
Sbjct: 474 YASKGNLREYLQARRPPGLEYCYNPS--------HNPEEQLSSKDLVSCAYQVARGMEYL 525
Query: 866 AEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFD 925
A K +HRDLAARN+LV E MKI+DFGL+RD++ D Y K + GR+PVKWMA E+LFD
Sbjct: 526 ASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFD 585
Query: 926 HIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLML 985
IYT QSDVWSFGVLLWEI TLGG+PYPG+P E LF LLK GHRM++P NC+ E+Y +M
Sbjct: 586 RIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMR 645
Query: 986 QCWKQEPDKRPVFADISKDLEKM--MVKRRDYLDLA 1019
CW P +RP F + +DL+++ + ++YLDL+
Sbjct: 646 DCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLS 681
>gi|13186251 fibroblast growth factor receptor 1 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 328 bits (840), Expect = 2e-89
Identities = 181/396 (45%), Positives = 248/396 (62%), Gaps = 30/396 (7%)
Query: 645 SFIVSVLLSAFCIHCYHKFAHKPPISSAEMTFRRPAQAFP------VSYSSSGAR----- 693
+F++S ++ + ++ K S +M + A++ P VS SS +
Sbjct: 382 AFLISCMVGSVIVYKMKSGTKKSDFHS-QMAVHKLAKSIPLRRQVTVSADSSASMNSGVL 440
Query: 694 --RPSLDSMENQ---VSVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHL-K 747
RPS S V +++ EDP+WE PR LVLGK LGEG FG+VV A A L K
Sbjct: 441 LVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDK 500
Query: 748 GRAGYTT-VAVKMLKENASPSELRDLLSEFNVLKQVN-HPHVIKLYGACSQDGPLLLIVE 805
+ T VAVKMLK +A+ +L DL+SE ++K + H ++I L GAC+QDGPL +IVE
Sbjct: 501 DKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVE 560
Query: 806 YAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYL 865
YA G+LR +L+ R G Y + H E L+ DL+S A+Q+++GM+YL
Sbjct: 561 YASKGNLREYLQARRPPGLEYCYNPS--------HNPEEQLSSKDLVSCAYQVARGMEYL 612
Query: 866 AEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFD 925
A K +HRDLAARN+LV E MKI+DFGL+RD++ D Y K + GR+PVKWMA E+LFD
Sbjct: 613 ASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFD 672
Query: 926 HIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLML 985
IYT QSDVWSFGVLLWEI TLGG+PYPG+P E LF LLK GHRM++P NC+ E+Y +M
Sbjct: 673 RIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMR 732
Query: 986 QCWKQEPDKRPVFADISKDLEKM--MVKRRDYLDLA 1019
CW P +RP F + +DL+++ + ++YLDL+
Sbjct: 733 DCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLS 768
>gi|105990522 fibroblast growth factor receptor 1 isoform 1 precursor
[Homo sapiens]
Length = 822
Score = 328 bits (840), Expect = 2e-89
Identities = 181/396 (45%), Positives = 248/396 (62%), Gaps = 30/396 (7%)
Query: 645 SFIVSVLLSAFCIHCYHKFAHKPPISSAEMTFRRPAQAFP------VSYSSSGAR----- 693
+F++S ++ + ++ K S +M + A++ P VS SS +
Sbjct: 384 AFLISCMVGSVIVYKMKSGTKKSDFHS-QMAVHKLAKSIPLRRQVTVSADSSASMNSGVL 442
Query: 694 --RPSLDSMENQ---VSVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHL-K 747
RPS S V +++ EDP+WE PR LVLGK LGEG FG+VV A A L K
Sbjct: 443 LVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDK 502
Query: 748 GRAGYTT-VAVKMLKENASPSELRDLLSEFNVLKQVN-HPHVIKLYGACSQDGPLLLIVE 805
+ T VAVKMLK +A+ +L DL+SE ++K + H ++I L GAC+QDGPL +IVE
Sbjct: 503 DKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVE 562
Query: 806 YAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYL 865
YA G+LR +L+ R G Y + H E L+ DL+S A+Q+++GM+YL
Sbjct: 563 YASKGNLREYLQARRPPGLEYCYNPS--------HNPEEQLSSKDLVSCAYQVARGMEYL 614
Query: 866 AEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFD 925
A K +HRDLAARN+LV E MKI+DFGL+RD++ D Y K + GR+PVKWMA E+LFD
Sbjct: 615 ASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFD 674
Query: 926 HIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLML 985
IYT QSDVWSFGVLLWEI TLGG+PYPG+P E LF LLK GHRM++P NC+ E+Y +M
Sbjct: 675 RIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKLLKEGHRMDKPSNCTNELYMMMR 734
Query: 986 QCWKQEPDKRPVFADISKDLEKM--MVKRRDYLDLA 1019
CW P +RP F + +DL+++ + ++YLDL+
Sbjct: 735 DCWHAVPSQRPTFKQLVEDLDRIVALTSNQEYLDLS 770
>gi|222144244 fibroblast growth factor receptor 2 isoform 9 precursor
[Homo sapiens]
Length = 680
Score = 324 bits (830), Expect = 3e-88
Identities = 170/344 (49%), Positives = 224/344 (65%), Gaps = 20/344 (5%)
Query: 670 SSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFPRKNLVLGKT 729
SS+ M P SS+ A P L V +++ EDPKWEFPR L LGK
Sbjct: 346 SSSSMNSNTPLVRITTRLSST-ADTPML------AGVSEYELPEDPKWEFPRDKLTLGKP 398
Query: 730 LGEGEFGKVVKATAFHL---KGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVN-HP 785
LGEG FG+VV A A + K + TVAVKMLK++A+ +L DL+SE ++K + H
Sbjct: 399 LGEGCFGQVVMAEAVGIDKDKPKEA-VTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHK 457
Query: 786 HVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERA 845
++I L GAC+QDGPL +IVEYA G+LR +LR R G Y S ++ E
Sbjct: 458 NIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEY--------SYDINRVPEEQ 509
Query: 846 LTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSY 905
+T DL+S +Q+++GM+YLA K +HRDLAARN+LV E MKI+DFGL+RD+ D Y
Sbjct: 510 MTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYY 569
Query: 906 VKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLK 965
K + GR+PVKWMA E+LFD +YT QSDVWSFGVL+WEI TLGG+PYPGIP E LF LLK
Sbjct: 570 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 629
Query: 966 TGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMM 1009
GHRM++P NC+ E+Y +M CW P +RP F + +DL++++
Sbjct: 630 EGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIL 673
>gi|222144231 fibroblast growth factor receptor 2 isoform 3 precursor
[Homo sapiens]
Length = 769
Score = 324 bits (830), Expect = 3e-88
Identities = 170/344 (49%), Positives = 224/344 (65%), Gaps = 20/344 (5%)
Query: 670 SSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFPRKNLVLGKT 729
SS+ M P SS+ A P L V +++ EDPKWEFPR L LGK
Sbjct: 435 SSSSMNSNTPLVRITTRLSST-ADTPML------AGVSEYELPEDPKWEFPRDKLTLGKP 487
Query: 730 LGEGEFGKVVKATAFHL---KGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVN-HP 785
LGEG FG+VV A A + K + TVAVKMLK++A+ +L DL+SE ++K + H
Sbjct: 488 LGEGCFGQVVMAEAVGIDKDKPKEA-VTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHK 546
Query: 786 HVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERA 845
++I L GAC+QDGPL +IVEYA G+LR +LR R G Y S ++ E
Sbjct: 547 NIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEY--------SYDINRVPEEQ 598
Query: 846 LTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSY 905
+T DL+S +Q+++GM+YLA K +HRDLAARN+LV E MKI+DFGL+RD+ D Y
Sbjct: 599 MTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYY 658
Query: 906 VKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLK 965
K + GR+PVKWMA E+LFD +YT QSDVWSFGVL+WEI TLGG+PYPGIP E LF LLK
Sbjct: 659 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 718
Query: 966 TGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMM 1009
GHRM++P NC+ E+Y +M CW P +RP F + +DL++++
Sbjct: 719 EGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIL 762
>gi|222144235 fibroblast growth factor receptor 2 isoform 5 precursor
[Homo sapiens]
Length = 707
Score = 324 bits (830), Expect = 3e-88
Identities = 170/344 (49%), Positives = 224/344 (65%), Gaps = 20/344 (5%)
Query: 670 SSAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFPRKNLVLGKT 729
SS+ M P SS+ A P L V +++ EDPKWEFPR L LGK
Sbjct: 345 SSSSMNSNTPLVRITTRLSST-ADTPML------AGVSEYELPEDPKWEFPRDKLTLGKP 397
Query: 730 LGEGEFGKVVKATAFHL---KGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVN-HP 785
LGEG FG+VV A A + K + TVAVKMLK++A+ +L DL+SE ++K + H
Sbjct: 398 LGEGCFGQVVMAEAVGIDKDKPKEA-VTVAVKMLKDDATEKDLSDLVSEMEMMKMIGKHK 456
Query: 786 HVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERA 845
++I L GAC+QDGPL +IVEYA G+LR +LR R G Y S ++ E
Sbjct: 457 NIINLLGACTQDGPLYVIVEYASKGNLREYLRARRPPGMEY--------SYDINRVPEEQ 508
Query: 846 LTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSY 905
+T DL+S +Q+++GM+YLA K +HRDLAARN+LV E MKI+DFGL+RD+ D Y
Sbjct: 509 MTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGLARDINNIDYY 568
Query: 906 VKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLK 965
K + GR+PVKWMA E+LFD +YT QSDVWSFGVL+WEI TLGG+PYPGIP E LF LLK
Sbjct: 569 KKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLMWEIFTLGGSPYPGIPVEELFKLLK 628
Query: 966 TGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMM 1009
GHRM++P NC+ E+Y +M CW P +RP F + +DL++++
Sbjct: 629 EGHRMDKPANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRIL 672
>gi|47524175 fibroblast growth factor receptor 4 isoform 1 precursor
[Homo sapiens]
Length = 802
Score = 321 bits (823), Expect = 2e-87
Identities = 187/396 (47%), Positives = 248/396 (62%), Gaps = 31/396 (7%)
Query: 638 IAAAVLFSFIVSVLLSAFCIHCYHKFAHKPPISSAEMTFRRPAQAFPVSYSSSGARRPSL 697
+A AVL +++ L +H H +PP + +++ A+ F + SSG SL
Sbjct: 378 LALAVLL--LLAGLYRGQALHGRHP---RPPATVQKLSRFPLARQFSLESGSSGKSSSSL 432
Query: 698 DS-----------MENQVSVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHL 746
+ VS+D + DP WEFPR LVLGK LGEG FG+VV+A AF +
Sbjct: 433 VRGVRLSSSGPALLAGLVSLD---LPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGM 489
Query: 747 KGRAG--YTTVAVKMLKENASPSELRDLLSEFNVLKQVN-HPHVIKLYGACSQDGPLLLI 803
+TVAVKMLK+NAS +L DL+SE V+K + H ++I L G C+Q+GPL +I
Sbjct: 490 DPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVI 549
Query: 804 VEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQ 863
VE A G+LR FLR R GP L G R+S E L+ L+S A+Q+++GMQ
Sbjct: 550 VECAAKGNLREFLRARRPPGPD-LSPDGPRSS-------EGPLSFPVLVSCAYQVARGMQ 601
Query: 864 YLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESL 923
YL K +HRDLAARN+LV E MKI+DFGL+R V+ D Y K S GR+PVKWMA E+L
Sbjct: 602 YLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEAL 661
Query: 924 FDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRL 983
FD +YT QSDVWSFG+LLWEI TLGG+PYPGIP E LF+LL+ GHRM+RP +C E+Y L
Sbjct: 662 FDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGL 721
Query: 984 MLQCWKQEPDKRPVFADISKDLEKMMVK-RRDYLDL 1018
M +CW P +RP F + + L+K+++ +YLDL
Sbjct: 722 MRECWHAAPSQRPTFKQLVEALDKVLLAVSEEYLDL 757
>gi|47524173 fibroblast growth factor receptor 4 isoform 1 precursor
[Homo sapiens]
Length = 802
Score = 321 bits (823), Expect = 2e-87
Identities = 187/396 (47%), Positives = 248/396 (62%), Gaps = 31/396 (7%)
Query: 638 IAAAVLFSFIVSVLLSAFCIHCYHKFAHKPPISSAEMTFRRPAQAFPVSYSSSGARRPSL 697
+A AVL +++ L +H H +PP + +++ A+ F + SSG SL
Sbjct: 378 LALAVLL--LLAGLYRGQALHGRHP---RPPATVQKLSRFPLARQFSLESGSSGKSSSSL 432
Query: 698 DS-----------MENQVSVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHL 746
+ VS+D + DP WEFPR LVLGK LGEG FG+VV+A AF +
Sbjct: 433 VRGVRLSSSGPALLAGLVSLD---LPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGM 489
Query: 747 KGRAG--YTTVAVKMLKENASPSELRDLLSEFNVLKQVN-HPHVIKLYGACSQDGPLLLI 803
+TVAVKMLK+NAS +L DL+SE V+K + H ++I L G C+Q+GPL +I
Sbjct: 490 DPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVI 549
Query: 804 VEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQ 863
VE A G+LR FLR R GP L G R+S E L+ L+S A+Q+++GMQ
Sbjct: 550 VECAAKGNLREFLRARRPPGPD-LSPDGPRSS-------EGPLSFPVLVSCAYQVARGMQ 601
Query: 864 YLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESL 923
YL K +HRDLAARN+LV E MKI+DFGL+R V+ D Y K S GR+PVKWMA E+L
Sbjct: 602 YLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPEAL 661
Query: 924 FDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRL 983
FD +YT QSDVWSFG+LLWEI TLGG+PYPGIP E LF+LL+ GHRM+RP +C E+Y L
Sbjct: 662 FDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGL 721
Query: 984 MLQCWKQEPDKRPVFADISKDLEKMMVK-RRDYLDL 1018
M +CW P +RP F + + L+K+++ +YLDL
Sbjct: 722 MRECWHAAPSQRPTFKQLVEALDKVLLAVSEEYLDL 757
>gi|47524177 fibroblast growth factor receptor 4 isoform 2 precursor
[Homo sapiens]
Length = 762
Score = 320 bits (820), Expect = 5e-87
Identities = 178/338 (52%), Positives = 228/338 (67%), Gaps = 20/338 (5%)
Query: 685 VSYSSSGARRPSLDSMENQVSVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAF 744
V SSSG P+L + VS+D + DP WEFPR LVLGK LGEG FG+VV+A AF
Sbjct: 396 VRLSSSG---PAL--LAGLVSLD---LPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAF 447
Query: 745 HLKGRAG--YTTVAVKMLKENASPSELRDLLSEFNVLKQVN-HPHVIKLYGACSQDGPLL 801
+ +TVAVKMLK+NAS +L DL+SE V+K + H ++I L G C+Q+GPL
Sbjct: 448 GMDPARPDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLY 507
Query: 802 LIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQG 861
+IVE A G+LR FLR R GP L G R+S E L+ L+S A+Q+++G
Sbjct: 508 VIVECAAKGNLREFLRARRPPGPD-LSPDGPRSS-------EGPLSFPVLVSCAYQVARG 559
Query: 862 MQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIE 921
MQYL K +HRDLAARN+LV E MKI+DFGL+R V+ D Y K S GR+PVKWMA E
Sbjct: 560 MQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLARGVHHIDYYKKTSNGRLPVKWMAPE 619
Query: 922 SLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMY 981
+LFD +YT QSDVWSFG+LLWEI TLGG+PYPGIP E LF+LL+ GHRM+RP +C E+Y
Sbjct: 620 ALFDRVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELY 679
Query: 982 RLMLQCWKQEPDKRPVFADISKDLEKMMVK-RRDYLDL 1018
LM +CW P +RP F + + L+K+++ +YLDL
Sbjct: 680 GLMRECWHAAPSQRPTFKQLVEALDKVLLAVSEEYLDL 717
>gi|11321597 kinase insert domain receptor precursor [Homo sapiens]
Length = 1356
Score = 274 bits (700), Expect = 4e-73
Identities = 156/375 (41%), Positives = 226/375 (60%), Gaps = 51/375 (13%)
Query: 716 KWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSE 775
KWEFPR L LGK LG G FG+V++A AF + A TVAVKMLKE A+ SE R L+SE
Sbjct: 826 KWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKTATCRTVAVKMLKEGATHSEHRALMSE 885
Query: 776 FNVLKQV-NHPHVIKLYGACSQ-DGPLLLIVEYAKYGSLRGFLRESR------------- 820
+L + +H +V+ L GAC++ GPL++IVE+ K+G+L +LR R
Sbjct: 886 LKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYKTKGARF 945
Query: 821 KVGPGYLGS------------GGSRNSSSLDHPDERA-----------------LTMGDL 851
+ G Y+G+ S++S+S +E++ LT+ L
Sbjct: 946 RQGKDYVGAIPVDLKRRLDSITSSQSSASSGFVEEKSLSDVEEEEAPEDLYKDFLTLEHL 1005
Query: 852 ISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQG 911
I +++Q+++GM++LA K +HRDLAARNIL++E +KI DFGL+RD+Y++ YV++
Sbjct: 1006 ICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDA 1065
Query: 912 RIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIP-PERLFNLLKTGHRM 970
R+P+KWMA E++FD +YT QSDVWSFGVLLWEI +LG +PYPG+ E LK G RM
Sbjct: 1066 RLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRM 1125
Query: 971 ERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKR-----RDYLDLAASTPSD 1025
PD + EMY+ ML CW EP +RP F+++ + L ++ +DY+ L S +
Sbjct: 1126 RAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDGKDYIVLPIS-ETL 1184
Query: 1026 SLIYDDGLSEEETPL 1040
S+ D GLS +P+
Sbjct: 1185 SMEEDSGLSLPTSPV 1199
>gi|13186249 fibroblast growth factor receptor 1 isoform 9 precursor
[Homo sapiens]
Length = 785
Score = 273 bits (699), Expect = 5e-73
Identities = 171/411 (41%), Positives = 234/411 (56%), Gaps = 46/411 (11%)
Query: 645 SFIVSVLLSAFCIHCYHKFAHKPPISSAEMTFRRPAQAFP------VSYSSSGAR----- 693
+F++S ++ + ++ K S +M + A++ P VS SS +
Sbjct: 384 AFLISCMVGSVIVYKMKSGTKKSDFHS-QMAVHKLAKSIPLRRQVTVSADSSASMNSGVL 442
Query: 694 --RPSLDSMENQ---VSVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHL-K 747
RPS S V +++ EDP+WE PR LVLGK LGEG FG+VV A A L K
Sbjct: 443 LVRPSRLSSSGTPMLAGVSEYELPEDPRWELPRDRLVLGKPLGEGCFGQVVLAEAIGLDK 502
Query: 748 GRAGYTT-VAVKMLKENASPSELRDLLSEFNVLKQVN-HPHVIKLYGACSQDGPLLLIVE 805
+ T VAVKMLK +A+ +L DL+SE ++K + H ++I L GAC+QDGPL +IVE
Sbjct: 503 DKPNRVTKVAVKMLKSDATEKDLSDLISEMEMMKMIGKHKNIINLLGACTQDGPLYVIVE 562
Query: 806 YAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYL 865
YA G+LR +L+ R G Y + H E L+ DL+S A+Q+++GM+YL
Sbjct: 563 YASKGNLREYLQARRPPGLEYCYNPS--------HNPEEQLSSKDLVSCAYQVARGMEYL 614
Query: 866 AEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFD 925
A K +HRDLAARN+LV E MKI+DFGL+RD++ D Y K + GR+PVKWMA E+LFD
Sbjct: 615 ASKKCIHRDLAARNVLVTEDNVMKIADFGLARDIHHIDYYKKTTNGRLPVKWMAPEALFD 674
Query: 926 HIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLML 985
IYT QSDVWSFGVLLWEI TLGG+PYPG+P E LF L E++ R++
Sbjct: 675 RIYTHQSDVWSFGVLLWEIFTLGGSPYPGVPVEELFKQL------------VEDLDRIVA 722
Query: 986 QCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEE 1036
QE + D+S L++ D S+ DS+ + L EE
Sbjct: 723 LTSNQE------YLDLSMPLDQYSPSFPDTRSSTCSSGEDSVFSHEPLPEE 767
>gi|4885631 tyrosine kinase with immunoglobulin-like and EGF-like
domains 1 [Homo sapiens]
Length = 1138
Score = 259 bits (663), Expect = 7e-69
Identities = 158/389 (40%), Positives = 225/389 (57%), Gaps = 43/389 (11%)
Query: 634 CRTVIAAAVLFSFIVSVLLSAFCIHCYHKFAHKPPISSAEMTFRRPAQAFPVSYSSSGAR 693
C T++AA + V + C+H F ++ S E T + + S + + R
Sbjct: 773 CLTILAA-----LLTLVCIRRSCLHRRRTFTYQS--GSGEETILQFS-----SGTLTLTR 820
Query: 694 RPSLDSMENQVSVDAFKILEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYT 753
RP L Q ++ +LE WE ++ +GEG FG+V++A +K
Sbjct: 821 RPKL-----QPEPLSYPVLE---WE----DITFEDLIGEGNFGQVIRAM---IKKDGLKM 865
Query: 754 TVAVKMLKENASPSELRDLLSEFNVL-KQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSL 812
A+KMLKE AS ++ RD E VL K +HP++I L GAC G L + +EYA YG+L
Sbjct: 866 NAAIKMLKEYASENDHRDFAGELEVLCKLGHHPNIINLLGACKNRGYLYIAIEYAPYGNL 925
Query: 813 RGFLRESR--KVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKL 870
FLR+SR + P + + +H L+ L+ FA + GMQYL+E +
Sbjct: 926 LDFLRKSRVLETDPAF----------AREHGTASTLSSRQLLRFASDAANGMQYLSEKQF 975
Query: 871 VHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTT 930
+HRDLAARN+LV E KI+DFGLSR E+ YVK++ GR+PV+WMAIESL +YTT
Sbjct: 976 IHRDLAARNVLVGENLASKIADFGLSRG---EEVYVKKTMGRLPVRWMAIESLNYSVYTT 1032
Query: 931 QSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQ 990
+SDVWSFGVLLWEIV+LGG PY G+ L+ L G+RME+P NC +E+Y LM QCW+
Sbjct: 1033 KSDVWSFGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRMEQPRNCDDEVYELMRQCWRD 1092
Query: 991 EPDKRPVFADISKDLEKMMVKRRDYLDLA 1019
P +RP FA I+ L +M+ R+ Y++++
Sbjct: 1093 RPYERPPFAQIALQLGRMLEARKAYVNMS 1121
>gi|88758596 TEK tyrosine kinase, endothelial precursor [Homo sapiens]
Length = 1124
Score = 244 bits (622), Expect = 4e-64
Identities = 131/291 (45%), Positives = 187/291 (64%), Gaps = 19/291 (6%)
Query: 730 LGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVL-KQVNHPHVI 788
+GEG FG+V+KA +K A+K +KE AS + RD E VL K +HP++I
Sbjct: 830 IGEGNFGQVLKA---RIKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNII 886
Query: 789 KLYGACSQDGPLLLIVEYAKYGSLRGFLRESR--KVGPGYLGSGGSRNSSSLDHPDERAL 846
L GAC G L L +EYA +G+L FLR+SR + P + + + ++ L
Sbjct: 887 NLLGACEHRGYLYLAIEYAPHGNLLDFLRKSRVLETDPAFAIANSTAST----------L 936
Query: 847 TMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYV 906
+ L+ FA +++GM YL++ + +HRDLAARNILV E KI+DFGLSR ++ YV
Sbjct: 937 SSQQLLHFAADVARGMDYLSQKQFIHRDLAARNILVGENYVAKIADFGLSRG---QEVYV 993
Query: 907 KRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKT 966
K++ GR+PV+WMAIESL +YTT SDVWS+GVLLWEIV+LGG PY G+ L+ L
Sbjct: 994 KKTMGRLPVRWMAIESLNYSVYTTNSDVWSYGVLLWEIVSLGGTPYCGMTCAELYEKLPQ 1053
Query: 967 GHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLD 1017
G+R+E+P NC +E+Y LM QCW+++P +RP FA I L +M+ +R+ Y++
Sbjct: 1054 GYRLEKPLNCDDEVYDLMRQCWREKPYERPSFAQILVSLNRMLEERKTYVN 1104
>gi|19924165 proto-oncogene c-ros-1 protein precursor [Homo sapiens]
Length = 2347
Score = 234 bits (596), Expect = 4e-61
Identities = 127/297 (42%), Positives = 176/297 (59%), Gaps = 29/297 (9%)
Query: 719 FPRKNLVLGKTLGEGEFGKVVKATAFHLKG-RAGYTTVAVKMLKENASPSELRDLLSEFN 777
FPR+ L L LG G FG+V + TA + G +G VAVK LK+ ++ E + L E +
Sbjct: 1940 FPREKLTLRLLLGSGAFGEVYEGTAVDILGVGSGEIKVAVKTLKKGSTDQEKIEFLKEAH 1999
Query: 778 VLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKV---GPGYLGSGGSRN 834
++ + NHP+++K G C + P +I+E + G L +LR++R GP
Sbjct: 2000 LMSKFNHPNILKQLGVCLLNEPQYIILELMEGGDLLTYLRKARMATFYGP---------- 2049
Query: 835 SSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVA-----EGRKMK 889
LT+ DL+ IS+G YL M +HRDLAARN LV+ R +K
Sbjct: 2050 ----------LLTLVDLVDLCVDISKGCVYLERMHFIHRDLAARNCLVSVKDYTSPRIVK 2099
Query: 890 ISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGG 949
I DFGL+RD+Y+ D Y KR +G +PV+WMA ESL D I+TTQSDVWSFG+L+WEI+TLG
Sbjct: 2100 IGDFGLARDIYKNDYYRKRGEGLLPVRWMAPESLMDGIFTTQSDVWSFGILIWEILTLGH 2159
Query: 950 NPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLE 1006
PYP + N ++TG R+E P NC ++++ LM QCW QEPD+RP F I L+
Sbjct: 2160 QPYPAHSNLDVLNYVQTGGRLEPPRNCPDDLWNLMTQCWAQEPDQRPTFHRIQDQLQ 2216
>gi|5031927 skeletal muscle receptor tyrosine kinase [Homo sapiens]
Length = 869
Score = 230 bits (587), Expect = 5e-60
Identities = 132/377 (35%), Positives = 199/377 (52%), Gaps = 19/377 (5%)
Query: 638 IAAAVLFSFIVSVLLSAFCIHCYHK---FAHKPPISSAEMTFRRPAQAFPVSYSSSGARR 694
+ +++ SF + VLL+ ++C + + +K S+A P++
Sbjct: 496 VIISIMSSFAIFVLLTITTLYCCRRRKQWKNKKRESAAVTLTTLPSELL----------- 544
Query: 695 PSLDSMENQVSVDAFKILEDPKW---EFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAG 751
LD + +L +PK E+PR N+ + +GEG FG+V +A A L
Sbjct: 545 --LDRLHPNPMYQRMPLLLNPKLLSLEYPRNNIEYVRDIGEGAFGRVFQARAPGLLPYEP 602
Query: 752 YTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGS 811
+T VAVKMLKE AS D E ++ + ++P+++KL G C+ P+ L+ EY YG
Sbjct: 603 FTMVAVKMLKEEASADMQADFQREAALMAEFDNPNIVKLLGVCAVGKPMCLLFEYMAYGD 662
Query: 812 LRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLV 871
L FLR L + + P L+ + + A Q++ GM YL+E K V
Sbjct: 663 LNEFLRSMSPHTVCSLSHSDLSMRAQVSSPGPPPLSCAEQLCIARQVAAGMAYLSERKFV 722
Query: 872 HRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQ 931
HRDLA RN LV E +KI+DFGLSR++Y D Y IP++WM ES+F + YTT+
Sbjct: 723 HRDLATRNCLVGENMVVKIADFGLSRNIYSADYYKANENDAIPIRWMPPESIFYNRYTTE 782
Query: 932 SDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQE 991
SDVW++GV+LWEI + G PY G+ E + ++ G+ + P+NC E+Y LM CW +
Sbjct: 783 SDVWAYGVVLWEIFSYGLQPYYGMAHEEVIYYVRDGNILSCPENCPVELYNLMRLCWSKL 842
Query: 992 PDKRPVFADISKDLEKM 1008
P RP F I + LE+M
Sbjct: 843 PADRPSFTSIHRILERM 859
>gi|4557665 insulin-like growth factor 1 receptor precursor [Homo
sapiens]
Length = 1367
Score = 223 bits (567), Expect = 1e-57
Identities = 117/294 (39%), Positives = 171/294 (58%), Gaps = 14/294 (4%)
Query: 716 KWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSE 775
+WE R+ + + + LG+G FG V + A + T VA+K + E AS E + L+E
Sbjct: 991 EWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNE 1050
Query: 776 FNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNS 835
+V+K+ N HV++L G SQ P L+I+E G L+ +LR R N+
Sbjct: 1051 ASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPE---------MENN 1101
Query: 836 SSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGL 895
L P ++ +I A +I+ GM YL K VHRDLAARN +VAE +KI DFG+
Sbjct: 1102 PVLAPP-----SLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGM 1156
Query: 896 SRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGI 955
+RD+YE D Y K +G +PV+WM+ ESL D ++TT SDVWSFGV+LWEI TL PY G+
Sbjct: 1157 TRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGL 1216
Query: 956 PPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMM 1009
E++ + G +++PDNC + ++ LM CW+ P RP F +I +++ M
Sbjct: 1217 SNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEM 1270
>gi|31657140 insulin receptor-related receptor precursor [Homo
sapiens]
Length = 1297
Score = 221 bits (563), Expect = 3e-57
Identities = 120/292 (41%), Positives = 169/292 (57%), Gaps = 14/292 (4%)
Query: 716 KWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSE 775
+WE PR+ + + + LG+G FG V + A L+ T VA+K + E ASP E + L E
Sbjct: 971 EWEVPREQISIIRELGQGSFGMVYEGLARGLEAGEESTPVALKTVNELASPRECIEFLKE 1030
Query: 776 FNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNS 835
+V+K HV++L G SQ P L+I+E G L+ LR R + N+
Sbjct: 1031 ASVMKAFKCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSHLRSLRPE---------AENN 1081
Query: 836 SSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGL 895
L P +G++I A +I+ GM YLA K VHRDLAARN +V++ +KI DFG+
Sbjct: 1082 PGLPQP-----ALGEMIQMAGEIADGMAYLAANKFVHRDLAARNCMVSQDFTVKIGDFGM 1136
Query: 896 SRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGI 955
+RDVYE D Y K +G +PV+WMA ESL D I+TT SDVWSFGV+LWEIVTL PY G+
Sbjct: 1137 TRDVYETDYYRKGGKGLLPVRWMAPESLKDGIFTTHSDVWSFGVVLWEIVTLAEQPYQGL 1196
Query: 956 PPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEK 1007
E++ + G +E + C ++ LM +CW+ P RP F I +++
Sbjct: 1197 SNEQVLKFVMDGGVLEELEGCPLQLQELMSRCWQPNPRLRPSFTHILDSIQE 1248
>gi|119395738 insulin receptor isoform Short precursor [Homo sapiens]
Length = 1370
Score = 220 bits (560), Expect = 6e-57
Identities = 126/341 (36%), Positives = 183/341 (53%), Gaps = 28/341 (8%)
Query: 716 KWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSE 775
+WE R+ + L + LG+G FG V + A + T VAVK + E+AS E + L+E
Sbjct: 1003 EWEVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNE 1062
Query: 776 FNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNS 835
+V+K HV++L G S+ P L+++E +G L+ +LR R
Sbjct: 1063 ASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRP-------------- 1108
Query: 836 SSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGL 895
+ ++P T+ ++I A +I+ GM YL K VHRDLAARN +VA +KI DFG+
Sbjct: 1109 EAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGM 1168
Query: 896 SRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGI 955
+RD+YE D Y K +G +PV+WMA ESL D ++TT SD+WSFGV+LWEI +L PY G+
Sbjct: 1169 TRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGL 1228
Query: 956 PPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDY 1015
E++ + G +++PDNC E + LM CW+ P RP F +I L+
Sbjct: 1229 SNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLKD-------- 1280
Query: 1016 LDLAASTPSDSLIYDD-----GLSEEETPLVDCNNAPLPRA 1051
DL S P S + + E E D N PL R+
Sbjct: 1281 -DLHPSFPEVSFFHSEENKAPESEELEMEFEDMENVPLDRS 1320
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,171,926
Number of Sequences: 37866
Number of extensions: 2163284
Number of successful extensions: 7290
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 558
Number of HSP's successfully gapped in prelim test: 277
Number of HSP's that attempted gapping in prelim test: 5050
Number of HSP's gapped (non-prelim): 1363
length of query: 1072
length of database: 18,247,518
effective HSP length: 113
effective length of query: 959
effective length of database: 13,968,660
effective search space: 13395944940
effective search space used: 13395944940
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.