Guide to the Human Genome
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Search of human proteins with 10835220

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b
[Homo sapiens]
         (994 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [...  1971   0.0  
gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [...  1969   0.0  
gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H...  1689   0.0  
gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [...  1689   0.0  
gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 ...  1629   0.0  
gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom...  1541   0.0  
gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom...  1541   0.0  
gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom...  1541   0.0  
gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom...  1541   0.0  
gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom...  1541   0.0  
gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom...  1541   0.0  
gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom...  1541   0.0  
gi|239751049 PREDICTED: similar to ATPase, Ca++ transporting, fa...  1157   0.0  
gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap...   459   e-129
gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap...   459   e-129
gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap...   459   e-129
gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap...   449   e-126
gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ...   441   e-123
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi...   365   e-101
gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]   360   3e-99
gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]             358   2e-98
gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]    356   7e-98
gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi...   355   1e-97
gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi...   355   1e-97
gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]   355   1e-97
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]   333   4e-91
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap...   299   8e-81
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa...   295   2e-79
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa...   295   2e-79
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa...   293   7e-79

>gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b
           [Homo sapiens]
          Length = 994

 Score = 1971 bits (5107), Expect = 0.0
 Identities = 994/994 (100%), Positives = 994/994 (100%)

Query: 1   MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 60
           MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL
Sbjct: 1   MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 60

Query: 61  LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120
           LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK
Sbjct: 61  LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120

Query: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180
           EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL
Sbjct: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180

Query: 181 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 240
           TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA
Sbjct: 181 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 240

Query: 241 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 300
           ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV
Sbjct: 241 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 300

Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360
           ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 361 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 420
           MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC
Sbjct: 361 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 420

Query: 421 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 480
           NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK
Sbjct: 421 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 480

Query: 481 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 540
           KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP
Sbjct: 481 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 540

Query: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML 600
           VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML
Sbjct: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML 600

Query: 601 DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD 660
           DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD
Sbjct: 601 DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD 660

Query: 661 LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM 720
           LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM
Sbjct: 661 LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM 720

Query: 721 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 780
           GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA
Sbjct: 721 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 780

Query: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI 840
           LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI
Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI 840

Query: 841 GGYVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMA 900
           GGYVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMA
Sbjct: 841 GGYVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMA 900

Query: 901 LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR 960
           LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR
Sbjct: 901 LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR 960

Query: 961 ALDLTQWLMVLKISLPVIGLDEILKFVARNYLEG 994
           ALDLTQWLMVLKISLPVIGLDEILKFVARNYLEG
Sbjct: 961 ALDLTQWLMVLKISLPVIGLDEILKFVARNYLEG 994


>gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a
           [Homo sapiens]
          Length = 1001

 Score = 1969 bits (5101), Expect = 0.0
 Identities = 993/993 (100%), Positives = 993/993 (100%)

Query: 1   MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 60
           MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL
Sbjct: 1   MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 60

Query: 61  LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120
           LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK
Sbjct: 61  LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120

Query: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180
           EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL
Sbjct: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180

Query: 181 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 240
           TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA
Sbjct: 181 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 240

Query: 241 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 300
           ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV
Sbjct: 241 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 300

Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360
           ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 361 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 420
           MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC
Sbjct: 361 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 420

Query: 421 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 480
           NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK
Sbjct: 421 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 480

Query: 481 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 540
           KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP
Sbjct: 481 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 540

Query: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML 600
           VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML
Sbjct: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML 600

Query: 601 DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD 660
           DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD
Sbjct: 601 DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD 660

Query: 661 LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM 720
           LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM
Sbjct: 661 LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM 720

Query: 721 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 780
           GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA
Sbjct: 721 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 780

Query: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI 840
           LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI
Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI 840

Query: 841 GGYVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMA 900
           GGYVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMA
Sbjct: 841 GGYVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMA 900

Query: 901 LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR 960
           LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR
Sbjct: 901 LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR 960

Query: 961 ALDLTQWLMVLKISLPVIGLDEILKFVARNYLE 993
           ALDLTQWLMVLKISLPVIGLDEILKFVARNYLE
Sbjct: 961 ALDLTQWLMVLKISLPVIGLDEILKFVARNYLE 993


>gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo
           sapiens]
          Length = 997

 Score = 1689 bits (4374), Expect = 0.0
 Identities = 838/993 (84%), Positives = 925/993 (93%), Gaps = 1/993 (0%)

Query: 1   MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 60
           ME AH KT EE L +FGV+E+TGL+ +QVK+  E++G NELPAEEGKTL ELVIEQFEDL
Sbjct: 1   MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60

Query: 61  LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120
           LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLIL+ANAIVGVWQERNAENAIEALK
Sbjct: 61  LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120

Query: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180
           EYEPEMGKVYR DRKSVQRIKA+DIVPGDIVE+AVGDKVPADIR+ +IKSTTLRVDQSIL
Sbjct: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180

Query: 181 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 240
           TGESVSVIKHT+PVPDPRAVNQDKKNMLFSGTNIAAGKA+G+V  TGV TEIGKIRD+M 
Sbjct: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240

Query: 241 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 300
           ATEQ++TPLQQKLDEFGEQLSKVISLIC+AVW+INIGHFNDPVHGGSW RGAIYYFKIAV
Sbjct: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300

Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360
           ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 361 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 420
           MSVC+MFI+D+V+GD C LNEF+ITGSTYAP GEV K+DKPV   QYDGLVELATICALC
Sbjct: 361 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 420

Query: 421 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 480
           NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+T+++ LSK+ERANACNSVI+QLMK
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 480

Query: 481 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 540
           KEFTLEFSRDRKSMSVYC+P K SR ++ +KMFVKGAPEGVIDRC ++RVG+T+VP+T  
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 539

Query: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML 600
           VK+KIM+VI+EWG+G DTLRCLALAT D P +REEM L+DSA F++YET+LTFVG VGML
Sbjct: 540 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 599

Query: 601 DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD 660
           DPPR EV  S++LCR AGIRVIMITGDNKGTA+AICRRIGIFG++E+V  +A+TGREFD+
Sbjct: 600 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDE 659

Query: 661 LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM 720
           L  + QR+AC  A CFARVEPSHKSKIVE+LQS+DEITAMTGDGVNDAPALKKAEIGIAM
Sbjct: 660 LNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAM 719

Query: 721 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 780
           GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA
Sbjct: 720 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 779

Query: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI 840
           LG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM++PPR+PKEPLISGWLFFRY+AI
Sbjct: 780 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAI 839

Query: 841 GGYVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMA 900
           G YVGAATVGAAAWWF+ A+ GP V++ QL+HF+QC EDN  FEG+DC +FE+P PMTMA
Sbjct: 840 GCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMA 899

Query: 901 LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR 960
           LSVLVTIEMCNALNSLSENQSLLRMPPW NIWL+GSICLSMSLHFLILYV+PLP+IF++ 
Sbjct: 900 LSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQIT 959

Query: 961 ALDLTQWLMVLKISLPVIGLDEILKFVARNYLE 993
            L++TQWLMVLKISLPVI +DE LKFVARNYLE
Sbjct: 960 PLNVTQWLMVLKISLPVILMDETLKFVARNYLE 992


>gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1
           [Homo sapiens]
          Length = 1042

 Score = 1689 bits (4374), Expect = 0.0
 Identities = 838/993 (84%), Positives = 925/993 (93%), Gaps = 1/993 (0%)

Query: 1   MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 60
           ME AH KT EE L +FGV+E+TGL+ +QVK+  E++G NELPAEEGKTL ELVIEQFEDL
Sbjct: 1   MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60

Query: 61  LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120
           LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLIL+ANAIVGVWQERNAENAIEALK
Sbjct: 61  LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120

Query: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180
           EYEPEMGKVYR DRKSVQRIKA+DIVPGDIVE+AVGDKVPADIR+ +IKSTTLRVDQSIL
Sbjct: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180

Query: 181 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 240
           TGESVSVIKHT+PVPDPRAVNQDKKNMLFSGTNIAAGKA+G+V  TGV TEIGKIRD+M 
Sbjct: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240

Query: 241 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 300
           ATEQ++TPLQQKLDEFGEQLSKVISLIC+AVW+INIGHFNDPVHGGSW RGAIYYFKIAV
Sbjct: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300

Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360
           ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 361 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 420
           MSVC+MFI+D+V+GD C LNEF+ITGSTYAP GEV K+DKPV   QYDGLVELATICALC
Sbjct: 361 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 420

Query: 421 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 480
           NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+T+++ LSK+ERANACNSVI+QLMK
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 480

Query: 481 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 540
           KEFTLEFSRDRKSMSVYC+P K SR ++ +KMFVKGAPEGVIDRC ++RVG+T+VP+T  
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 539

Query: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML 600
           VK+KIM+VI+EWG+G DTLRCLALAT D P +REEM L+DSA F++YET+LTFVG VGML
Sbjct: 540 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 599

Query: 601 DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD 660
           DPPR EV  S++LCR AGIRVIMITGDNKGTA+AICRRIGIFG++E+V  +A+TGREFD+
Sbjct: 600 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDE 659

Query: 661 LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM 720
           L  + QR+AC  A CFARVEPSHKSKIVE+LQS+DEITAMTGDGVNDAPALKKAEIGIAM
Sbjct: 660 LNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAM 719

Query: 721 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 780
           GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA
Sbjct: 720 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 779

Query: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI 840
           LG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM++PPR+PKEPLISGWLFFRY+AI
Sbjct: 780 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAI 839

Query: 841 GGYVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMA 900
           G YVGAATVGAAAWWF+ A+ GP V++ QL+HF+QC EDN  FEG+DC +FE+P PMTMA
Sbjct: 840 GCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMA 899

Query: 901 LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR 960
           LSVLVTIEMCNALNSLSENQSLLRMPPW NIWL+GSICLSMSLHFLILYV+PLP+IF++ 
Sbjct: 900 LSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQIT 959

Query: 961 ALDLTQWLMVLKISLPVIGLDEILKFVARNYLE 993
            L++TQWLMVLKISLPVI +DE LKFVARNYLE
Sbjct: 960 PLNVTQWLMVLKISLPVILMDETLKFVARNYLE 992


>gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3
           [Homo sapiens]
          Length = 1015

 Score = 1629 bits (4219), Expect = 0.0
 Identities = 814/993 (81%), Positives = 899/993 (90%), Gaps = 28/993 (2%)

Query: 1   MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 60
           ME AH KT EE L +FGV+E+TGL+ +QVK+  E++G NELPAEEGKTL ELVIEQFEDL
Sbjct: 1   MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNELPAEEGKTLLELVIEQFEDL 60

Query: 61  LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120
           LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLIL+ANAIVGVWQERNAENAIEALK
Sbjct: 61  LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK 120

Query: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180
           EYEPEMGKVYR DRKSVQRIKA+DIVPGDIVE+A                          
Sbjct: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIA-------------------------- 154

Query: 181 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 240
            GESVSVIKHT+PVPDPRAVNQDKKNMLFSGTNIAAGKA+G+V  TGV TEIGKIRD+M 
Sbjct: 155 -GESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 213

Query: 241 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 300
           ATEQ++TPLQQKLDEFGEQLSKVISLIC+AVW+INIGHFNDPVHGGSW RGAIYYFKIAV
Sbjct: 214 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 273

Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360
           ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 274 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 333

Query: 361 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 420
           MSVC+MFI+D+V+GD C LNEF+ITGSTYAP GEV K+DKPV   QYDGLVELATICALC
Sbjct: 334 MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 393

Query: 421 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 480
           NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+T+++ LSK+ERANACNSVI+QLMK
Sbjct: 394 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK 453

Query: 481 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 540
           KEFTLEFSRDRKSMSVYC+P K SR ++ +KMFVKGAPEGVIDRC ++RVG+T+VP+T  
Sbjct: 454 KEFTLEFSRDRKSMSVYCTPNKPSRTSM-SKMFVKGAPEGVIDRCTHIRVGSTKVPMTSG 512

Query: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML 600
           VK+KIM+VI+EWG+G DTLRCLALAT D P +REEM L+DSA F++YET+LTFVG VGML
Sbjct: 513 VKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGML 572

Query: 601 DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD 660
           DPPR EV  S++LCR AGIRVIMITGDNKGTA+AICRRIGIFG++E+V  +A+TGREFD+
Sbjct: 573 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDE 632

Query: 661 LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM 720
           L  + QR+AC  A CFARVEPSHKSKIVE+LQS+DEITAMTGDGVNDAPALKKAEIGIAM
Sbjct: 633 LNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAM 692

Query: 721 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 780
           GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA
Sbjct: 693 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 752

Query: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI 840
           LG PEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM++PPR+PKEPLISGWLFFRY+AI
Sbjct: 753 LGFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAI 812

Query: 841 GGYVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMA 900
           G YVGAATVGAAAWWF+ A+ GP V++ QL+HF+QC EDN  FEG+DC +FE+P PMTMA
Sbjct: 813 GCYVGAATVGAAAWWFIAADGGPRVSFYQLSHFLQCKEDNPDFEGVDCAIFESPYPMTMA 872

Query: 901 LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR 960
           LSVLVTIEMCNALNSLSENQSLLRMPPW NIWL+GSICLSMSLHFLILYV+PLP+IF++ 
Sbjct: 873 LSVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQIT 932

Query: 961 ALDLTQWLMVLKISLPVIGLDEILKFVARNYLE 993
            L++TQWLMVLKISLPVI +DE LKFVARNYLE
Sbjct: 933 PLNVTQWLMVLKISLPVILMDETLKFVARNYLE 965


>gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo
           sapiens]
          Length = 999

 Score = 1541 bits (3989), Expect = 0.0
 Identities = 758/992 (76%), Positives = 876/992 (88%)

Query: 1   MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 60
           MEAAH     + L +F V+   GL+P QV    E+YG NELP+EEGK+LWELV+EQFEDL
Sbjct: 1   MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60

Query: 61  LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120
           LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LIL+ANAIVGVWQERNAE+AIEALK
Sbjct: 61  LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120

Query: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180
           EYEPEMGKV R+DRK VQRI+ARDIVPGDIVEVAVGDKVPAD+R++ IKSTTLRVDQSIL
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180

Query: 181 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 240
           TGESVSV KHTE +PDPRAVNQDKKNMLFSGTNI +GKA+G+   TG+ TE+GKIR QMA
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240

Query: 241 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 300
           A E ++TPLQ+KLDEFG QLS  IS+ICVAVW+INIGHF DP HGGSW RGA+YYFKIAV
Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300

Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360
           ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 361 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 420
           MSVC+MF++ + D   CLL+EF+I+G+TY PEGEV + D+PVR GQ+DGLVELATICALC
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420

Query: 421 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 480
           NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+TD+++LS+VERA ACN+VI+QLM+
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480

Query: 481 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 540
           KEFTLEFSRDRKSMSVYC+P +      G+KMFVKGAPE VI+RC+ VRVG+   PLT  
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540

Query: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML 600
            +E+I+A I++WG+G DTLRCLALATRD PP++E+M LDD ++F++YETDLTFVG VGML
Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGML 600

Query: 601 DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD 660
           DPPR EV   I  C  AGIRV+MITGDNKGTA+AICRR+GIFG+ E+VA +AYTGREFDD
Sbjct: 601 DPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDD 660

Query: 661 LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM 720
           L   +QR+ACR A CFARVEP+HKS+IVE LQS++EITAMTGDGVNDAPALKKAEIGIAM
Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720

Query: 721 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 780
           GSGTAVAK+A+EMVL+DDNF++IVAAVEEGRAIY+NMKQFIRYLISSNVGEVVCIFLTA 
Sbjct: 721 GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAI 780

Query: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI 840
           LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM++ PRSP+E LISGWLFFRY+AI
Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAI 840

Query: 841 GGYVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMA 900
           G YVG ATV AA WWF+Y  +GPH+N+ QL +F++C+EDN  F GIDCEVFE+  P TMA
Sbjct: 841 GVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMA 900

Query: 901 LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR 960
           LSVLVTIEMCNALNS+SENQSLLRMPPW+N WLL ++ +SM+LHFLIL V PLP+IF++ 
Sbjct: 901 LSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVT 960

Query: 961 ALDLTQWLMVLKISLPVIGLDEILKFVARNYL 992
            L   QW++VL+ISLPVI LDE LK+++RN++
Sbjct: 961 PLSGRQWVVVLQISLPVILLDEALKYLSRNHM 992


>gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
           sapiens]
          Length = 1029

 Score = 1541 bits (3989), Expect = 0.0
 Identities = 758/992 (76%), Positives = 876/992 (88%)

Query: 1   MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 60
           MEAAH     + L +F V+   GL+P QV    E+YG NELP+EEGK+LWELV+EQFEDL
Sbjct: 1   MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60

Query: 61  LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120
           LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LIL+ANAIVGVWQERNAE+AIEALK
Sbjct: 61  LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120

Query: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180
           EYEPEMGKV R+DRK VQRI+ARDIVPGDIVEVAVGDKVPAD+R++ IKSTTLRVDQSIL
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180

Query: 181 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 240
           TGESVSV KHTE +PDPRAVNQDKKNMLFSGTNI +GKA+G+   TG+ TE+GKIR QMA
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240

Query: 241 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 300
           A E ++TPLQ+KLDEFG QLS  IS+ICVAVW+INIGHF DP HGGSW RGA+YYFKIAV
Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300

Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360
           ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 361 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 420
           MSVC+MF++ + D   CLL+EF+I+G+TY PEGEV + D+PVR GQ+DGLVELATICALC
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420

Query: 421 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 480
           NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+TD+++LS+VERA ACN+VI+QLM+
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480

Query: 481 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 540
           KEFTLEFSRDRKSMSVYC+P +      G+KMFVKGAPE VI+RC+ VRVG+   PLT  
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540

Query: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML 600
            +E+I+A I++WG+G DTLRCLALATRD PP++E+M LDD ++F++YETDLTFVG VGML
Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGML 600

Query: 601 DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD 660
           DPPR EV   I  C  AGIRV+MITGDNKGTA+AICRR+GIFG+ E+VA +AYTGREFDD
Sbjct: 601 DPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDD 660

Query: 661 LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM 720
           L   +QR+ACR A CFARVEP+HKS+IVE LQS++EITAMTGDGVNDAPALKKAEIGIAM
Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720

Query: 721 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 780
           GSGTAVAK+A+EMVL+DDNF++IVAAVEEGRAIY+NMKQFIRYLISSNVGEVVCIFLTA 
Sbjct: 721 GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAI 780

Query: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI 840
           LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM++ PRSP+E LISGWLFFRY+AI
Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAI 840

Query: 841 GGYVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMA 900
           G YVG ATV AA WWF+Y  +GPH+N+ QL +F++C+EDN  F GIDCEVFE+  P TMA
Sbjct: 841 GVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMA 900

Query: 901 LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR 960
           LSVLVTIEMCNALNS+SENQSLLRMPPW+N WLL ++ +SM+LHFLIL V PLP+IF++ 
Sbjct: 901 LSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVT 960

Query: 961 ALDLTQWLMVLKISLPVIGLDEILKFVARNYL 992
            L   QW++VL+ISLPVI LDE LK+++RN++
Sbjct: 961 PLSGRQWVVVLQISLPVILLDEALKYLSRNHM 992


>gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo
           sapiens]
          Length = 998

 Score = 1541 bits (3989), Expect = 0.0
 Identities = 758/992 (76%), Positives = 876/992 (88%)

Query: 1   MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 60
           MEAAH     + L +F V+   GL+P QV    E+YG NELP+EEGK+LWELV+EQFEDL
Sbjct: 1   MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60

Query: 61  LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120
           LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LIL+ANAIVGVWQERNAE+AIEALK
Sbjct: 61  LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120

Query: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180
           EYEPEMGKV R+DRK VQRI+ARDIVPGDIVEVAVGDKVPAD+R++ IKSTTLRVDQSIL
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180

Query: 181 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 240
           TGESVSV KHTE +PDPRAVNQDKKNMLFSGTNI +GKA+G+   TG+ TE+GKIR QMA
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240

Query: 241 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 300
           A E ++TPLQ+KLDEFG QLS  IS+ICVAVW+INIGHF DP HGGSW RGA+YYFKIAV
Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300

Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360
           ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 361 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 420
           MSVC+MF++ + D   CLL+EF+I+G+TY PEGEV + D+PVR GQ+DGLVELATICALC
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420

Query: 421 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 480
           NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+TD+++LS+VERA ACN+VI+QLM+
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480

Query: 481 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 540
           KEFTLEFSRDRKSMSVYC+P +      G+KMFVKGAPE VI+RC+ VRVG+   PLT  
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540

Query: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML 600
            +E+I+A I++WG+G DTLRCLALATRD PP++E+M LDD ++F++YETDLTFVG VGML
Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGML 600

Query: 601 DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD 660
           DPPR EV   I  C  AGIRV+MITGDNKGTA+AICRR+GIFG+ E+VA +AYTGREFDD
Sbjct: 601 DPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDD 660

Query: 661 LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM 720
           L   +QR+ACR A CFARVEP+HKS+IVE LQS++EITAMTGDGVNDAPALKKAEIGIAM
Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720

Query: 721 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 780
           GSGTAVAK+A+EMVL+DDNF++IVAAVEEGRAIY+NMKQFIRYLISSNVGEVVCIFLTA 
Sbjct: 721 GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAI 780

Query: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI 840
           LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM++ PRSP+E LISGWLFFRY+AI
Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAI 840

Query: 841 GGYVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMA 900
           G YVG ATV AA WWF+Y  +GPH+N+ QL +F++C+EDN  F GIDCEVFE+  P TMA
Sbjct: 841 GVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMA 900

Query: 901 LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR 960
           LSVLVTIEMCNALNS+SENQSLLRMPPW+N WLL ++ +SM+LHFLIL V PLP+IF++ 
Sbjct: 901 LSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVT 960

Query: 961 ALDLTQWLMVLKISLPVIGLDEILKFVARNYL 992
            L   QW++VL+ISLPVI LDE LK+++RN++
Sbjct: 961 PLSGRQWVVVLQISLPVILLDEALKYLSRNHM 992


>gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
           sapiens]
          Length = 1029

 Score = 1541 bits (3989), Expect = 0.0
 Identities = 758/992 (76%), Positives = 876/992 (88%)

Query: 1   MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 60
           MEAAH     + L +F V+   GL+P QV    E+YG NELP+EEGK+LWELV+EQFEDL
Sbjct: 1   MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60

Query: 61  LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120
           LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LIL+ANAIVGVWQERNAE+AIEALK
Sbjct: 61  LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120

Query: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180
           EYEPEMGKV R+DRK VQRI+ARDIVPGDIVEVAVGDKVPAD+R++ IKSTTLRVDQSIL
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180

Query: 181 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 240
           TGESVSV KHTE +PDPRAVNQDKKNMLFSGTNI +GKA+G+   TG+ TE+GKIR QMA
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240

Query: 241 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 300
           A E ++TPLQ+KLDEFG QLS  IS+ICVAVW+INIGHF DP HGGSW RGA+YYFKIAV
Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300

Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360
           ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 361 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 420
           MSVC+MF++ + D   CLL+EF+I+G+TY PEGEV + D+PVR GQ+DGLVELATICALC
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420

Query: 421 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 480
           NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+TD+++LS+VERA ACN+VI+QLM+
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480

Query: 481 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 540
           KEFTLEFSRDRKSMSVYC+P +      G+KMFVKGAPE VI+RC+ VRVG+   PLT  
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540

Query: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML 600
            +E+I+A I++WG+G DTLRCLALATRD PP++E+M LDD ++F++YETDLTFVG VGML
Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGML 600

Query: 601 DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD 660
           DPPR EV   I  C  AGIRV+MITGDNKGTA+AICRR+GIFG+ E+VA +AYTGREFDD
Sbjct: 601 DPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDD 660

Query: 661 LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM 720
           L   +QR+ACR A CFARVEP+HKS+IVE LQS++EITAMTGDGVNDAPALKKAEIGIAM
Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720

Query: 721 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 780
           GSGTAVAK+A+EMVL+DDNF++IVAAVEEGRAIY+NMKQFIRYLISSNVGEVVCIFLTA 
Sbjct: 721 GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAI 780

Query: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI 840
           LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM++ PRSP+E LISGWLFFRY+AI
Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAI 840

Query: 841 GGYVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMA 900
           G YVG ATV AA WWF+Y  +GPH+N+ QL +F++C+EDN  F GIDCEVFE+  P TMA
Sbjct: 841 GVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMA 900

Query: 901 LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR 960
           LSVLVTIEMCNALNS+SENQSLLRMPPW+N WLL ++ +SM+LHFLIL V PLP+IF++ 
Sbjct: 901 LSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVT 960

Query: 961 ALDLTQWLMVLKISLPVIGLDEILKFVARNYL 992
            L   QW++VL+ISLPVI LDE LK+++RN++
Sbjct: 961 PLSGRQWVVVLQISLPVILLDEALKYLSRNHM 992


>gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo
           sapiens]
          Length = 1043

 Score = 1541 bits (3989), Expect = 0.0
 Identities = 758/992 (76%), Positives = 876/992 (88%)

Query: 1   MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 60
           MEAAH     + L +F V+   GL+P QV    E+YG NELP+EEGK+LWELV+EQFEDL
Sbjct: 1   MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60

Query: 61  LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120
           LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LIL+ANAIVGVWQERNAE+AIEALK
Sbjct: 61  LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120

Query: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180
           EYEPEMGKV R+DRK VQRI+ARDIVPGDIVEVAVGDKVPAD+R++ IKSTTLRVDQSIL
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180

Query: 181 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 240
           TGESVSV KHTE +PDPRAVNQDKKNMLFSGTNI +GKA+G+   TG+ TE+GKIR QMA
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240

Query: 241 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 300
           A E ++TPLQ+KLDEFG QLS  IS+ICVAVW+INIGHF DP HGGSW RGA+YYFKIAV
Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300

Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360
           ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 361 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 420
           MSVC+MF++ + D   CLL+EF+I+G+TY PEGEV + D+PVR GQ+DGLVELATICALC
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420

Query: 421 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 480
           NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+TD+++LS+VERA ACN+VI+QLM+
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480

Query: 481 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 540
           KEFTLEFSRDRKSMSVYC+P +      G+KMFVKGAPE VI+RC+ VRVG+   PLT  
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540

Query: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML 600
            +E+I+A I++WG+G DTLRCLALATRD PP++E+M LDD ++F++YETDLTFVG VGML
Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGML 600

Query: 601 DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD 660
           DPPR EV   I  C  AGIRV+MITGDNKGTA+AICRR+GIFG+ E+VA +AYTGREFDD
Sbjct: 601 DPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDD 660

Query: 661 LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM 720
           L   +QR+ACR A CFARVEP+HKS+IVE LQS++EITAMTGDGVNDAPALKKAEIGIAM
Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720

Query: 721 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 780
           GSGTAVAK+A+EMVL+DDNF++IVAAVEEGRAIY+NMKQFIRYLISSNVGEVVCIFLTA 
Sbjct: 721 GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAI 780

Query: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI 840
           LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM++ PRSP+E LISGWLFFRY+AI
Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAI 840

Query: 841 GGYVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMA 900
           G YVG ATV AA WWF+Y  +GPH+N+ QL +F++C+EDN  F GIDCEVFE+  P TMA
Sbjct: 841 GVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMA 900

Query: 901 LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR 960
           LSVLVTIEMCNALNS+SENQSLLRMPPW+N WLL ++ +SM+LHFLIL V PLP+IF++ 
Sbjct: 901 LSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVT 960

Query: 961 ALDLTQWLMVLKISLPVIGLDEILKFVARNYL 992
            L   QW++VL+ISLPVI LDE LK+++RN++
Sbjct: 961 PLSGRQWVVVLQISLPVILLDEALKYLSRNHM 992


>gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo
           sapiens]
          Length = 1044

 Score = 1541 bits (3989), Expect = 0.0
 Identities = 758/992 (76%), Positives = 876/992 (88%)

Query: 1   MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 60
           MEAAH     + L +F V+   GL+P QV    E+YG NELP+EEGK+LWELV+EQFEDL
Sbjct: 1   MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60

Query: 61  LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120
           LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LIL+ANAIVGVWQERNAE+AIEALK
Sbjct: 61  LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120

Query: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180
           EYEPEMGKV R+DRK VQRI+ARDIVPGDIVEVAVGDKVPAD+R++ IKSTTLRVDQSIL
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180

Query: 181 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 240
           TGESVSV KHTE +PDPRAVNQDKKNMLFSGTNI +GKA+G+   TG+ TE+GKIR QMA
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240

Query: 241 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 300
           A E ++TPLQ+KLDEFG QLS  IS+ICVAVW+INIGHF DP HGGSW RGA+YYFKIAV
Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300

Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360
           ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 361 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 420
           MSVC+MF++ + D   CLL+EF+I+G+TY PEGEV + D+PVR GQ+DGLVELATICALC
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420

Query: 421 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 480
           NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+TD+++LS+VERA ACN+VI+QLM+
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480

Query: 481 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 540
           KEFTLEFSRDRKSMSVYC+P +      G+KMFVKGAPE VI+RC+ VRVG+   PLT  
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540

Query: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML 600
            +E+I+A I++WG+G DTLRCLALATRD PP++E+M LDD ++F++YETDLTFVG VGML
Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGML 600

Query: 601 DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD 660
           DPPR EV   I  C  AGIRV+MITGDNKGTA+AICRR+GIFG+ E+VA +AYTGREFDD
Sbjct: 601 DPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDD 660

Query: 661 LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM 720
           L   +QR+ACR A CFARVEP+HKS+IVE LQS++EITAMTGDGVNDAPALKKAEIGIAM
Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720

Query: 721 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 780
           GSGTAVAK+A+EMVL+DDNF++IVAAVEEGRAIY+NMKQFIRYLISSNVGEVVCIFLTA 
Sbjct: 721 GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAI 780

Query: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI 840
           LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM++ PRSP+E LISGWLFFRY+AI
Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAI 840

Query: 841 GGYVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMA 900
           G YVG ATV AA WWF+Y  +GPH+N+ QL +F++C+EDN  F GIDCEVFE+  P TMA
Sbjct: 841 GVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMA 900

Query: 901 LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR 960
           LSVLVTIEMCNALNS+SENQSLLRMPPW+N WLL ++ +SM+LHFLIL V PLP+IF++ 
Sbjct: 901 LSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVT 960

Query: 961 ALDLTQWLMVLKISLPVIGLDEILKFVARNYL 992
            L   QW++VL+ISLPVI LDE LK+++RN++
Sbjct: 961 PLSGRQWVVVLQISLPVILLDEALKYLSRNHM 992


>gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo
           sapiens]
          Length = 1052

 Score = 1541 bits (3989), Expect = 0.0
 Identities = 758/992 (76%), Positives = 876/992 (88%)

Query: 1   MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 60
           MEAAH     + L +F V+   GL+P QV    E+YG NELP+EEGK+LWELV+EQFEDL
Sbjct: 1   MEAAHLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL 60

Query: 61  LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120
           LVRILLLAA +SFVLAWFEEGEET TAFVEP VI+LIL+ANAIVGVWQERNAE+AIEALK
Sbjct: 61  LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120

Query: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180
           EYEPEMGKV R+DRK VQRI+ARDIVPGDIVEVAVGDKVPAD+R++ IKSTTLRVDQSIL
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180

Query: 181 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 240
           TGESVSV KHTE +PDPRAVNQDKKNMLFSGTNI +GKA+G+   TG+ TE+GKIR QMA
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMA 240

Query: 241 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 300
           A E ++TPLQ+KLDEFG QLS  IS+ICVAVW+INIGHF DP HGGSW RGA+YYFKIAV
Sbjct: 241 AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV 300

Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360
           ALAVAAIPEGLPAVITTCLALGTRRMA+KNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360

Query: 361 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 420
           MSVC+MF++ + D   CLL+EF+I+G+TY PEGEV + D+PVR GQ+DGLVELATICALC
Sbjct: 361 MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC 420

Query: 421 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 480
           NDS+LD+NEAKGVYEKVGEATETALT LVEKMNVF+TD+++LS+VERA ACN+VI+QLM+
Sbjct: 421 NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR 480

Query: 481 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 540
           KEFTLEFSRDRKSMSVYC+P +      G+KMFVKGAPE VI+RC+ VRVG+   PLT  
Sbjct: 481 KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRTAPLTPT 540

Query: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML 600
            +E+I+A I++WG+G DTLRCLALATRD PP++E+M LDD ++F++YETDLTFVG VGML
Sbjct: 541 SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGML 600

Query: 601 DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD 660
           DPPR EV   I  C  AGIRV+MITGDNKGTA+AICRR+GIFG+ E+VA +AYTGREFDD
Sbjct: 601 DPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDD 660

Query: 661 LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM 720
           L   +QR+ACR A CFARVEP+HKS+IVE LQS++EITAMTGDGVNDAPALKKAEIGIAM
Sbjct: 661 LSPEQQRQACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM 720

Query: 721 GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA 780
           GSGTAVAK+A+EMVL+DDNF++IVAAVEEGRAIY+NMKQFIRYLISSNVGEVVCIFLTA 
Sbjct: 721 GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAI 780

Query: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI 840
           LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIM++ PRSP+E LISGWLFFRY+AI
Sbjct: 781 LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAI 840

Query: 841 GGYVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMA 900
           G YVG ATV AA WWF+Y  +GPH+N+ QL +F++C+EDN  F GIDCEVFE+  P TMA
Sbjct: 841 GVYVGLATVAAATWWFVYDAEGPHINFYQLRNFLKCSEDNPLFAGIDCEVFESRFPTTMA 900

Query: 901 LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR 960
           LSVLVTIEMCNALNS+SENQSLLRMPPW+N WLL ++ +SM+LHFLIL V PLP+IF++ 
Sbjct: 901 LSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVT 960

Query: 961 ALDLTQWLMVLKISLPVIGLDEILKFVARNYL 992
            L   QW++VL+ISLPVI LDE LK+++RN++
Sbjct: 961 PLSGRQWVVVLQISLPVILLDEALKYLSRNHM 992


>gi|239751049 PREDICTED: similar to ATPase, Ca++ transporting, fast
           twitch 1 [Homo sapiens]
          Length = 879

 Score = 1157 bits (2993), Expect = 0.0
 Identities = 588/588 (100%), Positives = 588/588 (100%)

Query: 1   MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 60
           MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL
Sbjct: 256 MEAAHAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDL 315

Query: 61  LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120
           LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK
Sbjct: 316 LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 375

Query: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180
           EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL
Sbjct: 376 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 435

Query: 181 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 240
           TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA
Sbjct: 436 TGESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMA 495

Query: 241 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 300
           ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV
Sbjct: 496 ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV 555

Query: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360
           ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
Sbjct: 556 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 615

Query: 361 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 420
           MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC
Sbjct: 616 MSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALC 675

Query: 421 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 480
           NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK
Sbjct: 676 NDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMK 735

Query: 481 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 540
           KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP
Sbjct: 736 KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP 795

Query: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYE 588
           VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYE
Sbjct: 796 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYE 843


>gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo
           sapiens]
          Length = 939

 Score =  459 bits (1180), Expect = e-129
 Identities = 324/978 (33%), Positives = 498/978 (50%), Gaps = 131/978 (13%)

Query: 23  GLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWFEEGE 82
           GL   +V      +G NE    E + LW+  I QF++ L+ +LL +A IS ++  F++  
Sbjct: 45  GLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDA- 103

Query: 83  ETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKA 142
                 V   V +LI++  A V   QE  +E ++E L +  P      R  +  ++   A
Sbjct: 104 ------VSITVAILIVVTVAFV---QEYRSEKSLEELSKLVPPECHCVREGK--LEHTLA 152

Query: 143 RDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQ 202
           RD+VPGD V ++VGD+VPAD+R+   ++  L +D+S LTGE+    K T   P P A N 
Sbjct: 153 RDLVPGDTVCLSVGDRVPADLRLF--EAVDLSIDESSLTGETTPCSKVT--APQPAATNG 208

Query: 203 D---KKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAATEQDKTPLQQKLDEFGEQ 259
           D   + N+ F GT +  GKA G+V  TG  +E G++   M A E  KTPLQ+ +D  G+Q
Sbjct: 209 DLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQ 268

Query: 260 LS----KVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVALAVAAIPEGLPAVI 315
           LS     +I +I +  WL+               +  +  F I+V+LAVAAIPEGLP V+
Sbjct: 269 LSFYSFGIIGIIMLVGWLLG--------------KDILEMFTISVSLAVAAIPEGLPIVV 314

Query: 316 TTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGD 375
           T  LALG  RM KK AIV+ LP VETLGC +VICSDKTGTLT N+M+V  +F  D +  +
Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374

Query: 376 ICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCNDSSLDFNEAKGVYE 435
           +        TG  Y   GEV+ +   V       +  +     +CND+ +  N       
Sbjct: 375 V--------TGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTL----- 421

Query: 436 KVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMS 495
            +G+ TE AL  L  KM +       + K E                    FS ++K M+
Sbjct: 422 -MGKPTEGALIALAMKMGLDGLQQDYIRKAE------------------YPFSSEQKWMA 462

Query: 496 VYC-SPAKSSRAAVGNKMFVKGAPEGVIDRCN-YVRVGTTRVPLTGPVKEKIMAVIKEWG 553
           V C    +  R  +    F+KGA E VI  C  Y   G T   LT   +++ +   ++  
Sbjct: 463 VKCVHRTQQDRPEI---CFMKGAYEQVIKYCTTYQSKGQT---LTLTQQQRDVYQQEKAR 516

Query: 554 TGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGMLDPPRKEVTGSIQL 613
            G   LR LALA+    P+  +               LTF+G+VG++DPPR  V  ++  
Sbjct: 517 MGSAGLRVLALASG---PELGQ---------------LTFLGLVGIIDPPRTGVKEAVTT 558

Query: 614 CRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREACRRA 673
              +G+ + MITGD++ TA+AI  R+G++ +  +    + +G E D + + +  +   + 
Sbjct: 559 LIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ----SVSGEEIDAMDVQQLSQIVPKV 614

Query: 674 CCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASE 732
             F R  P HK KI++ LQ    + AMTGDGVNDA ALK A+IG+AMG +GT V K A++
Sbjct: 615 AVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAAD 674

Query: 733 MVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQL 792
           M+L DD+F TI++A+EEG+ IYNN+K F+R+ +S+++  +  I L   +  P  L  +Q+
Sbjct: 675 MILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQI 734

Query: 793 LWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYVGAATVGAA 852
           LW+N++ DG PA +LG  P D D++ +PPR+ K+ +++  L  + +     +   T    
Sbjct: 735 LWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIVCGT---- 790

Query: 853 AWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTIEMCNA 912
                            L  F +   DN             P   TM  +  V  +M NA
Sbjct: 791 -----------------LFVFWRELRDNV----------ITPRDTTMTFTCFVFFDMFNA 823

Query: 913 LNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQWLMVLK 972
           L+S S+ +S+  +    N     ++  S+    L++Y  PL  +F+  +L +   L +L 
Sbjct: 824 LSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLG 883

Query: 973 ISLPVIGLDEILKFVARN 990
           ++  V  + EI+K V R+
Sbjct: 884 LTSSVCIVAEIIKKVERS 901


>gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo
           sapiens]
          Length = 949

 Score =  459 bits (1180), Expect = e-129
 Identities = 324/978 (33%), Positives = 498/978 (50%), Gaps = 131/978 (13%)

Query: 23  GLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWFEEGE 82
           GL   +V      +G NE    E + LW+  I QF++ L+ +LL +A IS ++  F++  
Sbjct: 45  GLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDA- 103

Query: 83  ETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKA 142
                 V   V +LI++  A V   QE  +E ++E L +  P      R  +  ++   A
Sbjct: 104 ------VSITVAILIVVTVAFV---QEYRSEKSLEELSKLVPPECHCVREGK--LEHTLA 152

Query: 143 RDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQ 202
           RD+VPGD V ++VGD+VPAD+R+   ++  L +D+S LTGE+    K T   P P A N 
Sbjct: 153 RDLVPGDTVCLSVGDRVPADLRLF--EAVDLSIDESSLTGETTPCSKVT--APQPAATNG 208

Query: 203 D---KKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAATEQDKTPLQQKLDEFGEQ 259
           D   + N+ F GT +  GKA G+V  TG  +E G++   M A E  KTPLQ+ +D  G+Q
Sbjct: 209 DLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQ 268

Query: 260 LS----KVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVALAVAAIPEGLPAVI 315
           LS     +I +I +  WL+               +  +  F I+V+LAVAAIPEGLP V+
Sbjct: 269 LSFYSFGIIGIIMLVGWLLG--------------KDILEMFTISVSLAVAAIPEGLPIVV 314

Query: 316 TTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGD 375
           T  LALG  RM KK AIV+ LP VETLGC +VICSDKTGTLT N+M+V  +F  D +  +
Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374

Query: 376 ICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCNDSSLDFNEAKGVYE 435
           +        TG  Y   GEV+ +   V       +  +     +CND+ +  N       
Sbjct: 375 V--------TGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTL----- 421

Query: 436 KVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMS 495
            +G+ TE AL  L  KM +       + K E                    FS ++K M+
Sbjct: 422 -MGKPTEGALIALAMKMGLDGLQQDYIRKAE------------------YPFSSEQKWMA 462

Query: 496 VYC-SPAKSSRAAVGNKMFVKGAPEGVIDRCN-YVRVGTTRVPLTGPVKEKIMAVIKEWG 553
           V C    +  R  +    F+KGA E VI  C  Y   G T   LT   +++ +   ++  
Sbjct: 463 VKCVHRTQQDRPEI---CFMKGAYEQVIKYCTTYQSKGQT---LTLTQQQRDVYQQEKAR 516

Query: 554 TGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGMLDPPRKEVTGSIQL 613
            G   LR LALA+    P+  +               LTF+G+VG++DPPR  V  ++  
Sbjct: 517 MGSAGLRVLALASG---PELGQ---------------LTFLGLVGIIDPPRTGVKEAVTT 558

Query: 614 CRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREACRRA 673
              +G+ + MITGD++ TA+AI  R+G++ +  +    + +G E D + + +  +   + 
Sbjct: 559 LIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ----SVSGEEIDAMDVQQLSQIVPKV 614

Query: 674 CCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASE 732
             F R  P HK KI++ LQ    + AMTGDGVNDA ALK A+IG+AMG +GT V K A++
Sbjct: 615 AVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAAD 674

Query: 733 MVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQL 792
           M+L DD+F TI++A+EEG+ IYNN+K F+R+ +S+++  +  I L   +  P  L  +Q+
Sbjct: 675 MILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQI 734

Query: 793 LWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYVGAATVGAA 852
           LW+N++ DG PA +LG  P D D++ +PPR+ K+ +++  L  + +     +   T    
Sbjct: 735 LWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIVCGT---- 790

Query: 853 AWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTIEMCNA 912
                            L  F +   DN             P   TM  +  V  +M NA
Sbjct: 791 -----------------LFVFWRELRDNV----------ITPRDTTMTFTCFVFFDMFNA 823

Query: 913 LNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQWLMVLK 972
           L+S S+ +S+  +    N     ++  S+    L++Y  PL  +F+  +L +   L +L 
Sbjct: 824 LSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLG 883

Query: 973 ISLPVIGLDEILKFVARN 990
           ++  V  + EI+K V R+
Sbjct: 884 LTSSVCIVAEIIKKVERS 901


>gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo
           sapiens]
          Length = 919

 Score =  459 bits (1180), Expect = e-129
 Identities = 324/978 (33%), Positives = 498/978 (50%), Gaps = 131/978 (13%)

Query: 23  GLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWFEEGE 82
           GL   +V      +G NE    E + LW+  I QF++ L+ +LL +A IS ++  F++  
Sbjct: 45  GLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDA- 103

Query: 83  ETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKA 142
                 V   V +LI++  A V   QE  +E ++E L +  P      R  +  ++   A
Sbjct: 104 ------VSITVAILIVVTVAFV---QEYRSEKSLEELSKLVPPECHCVREGK--LEHTLA 152

Query: 143 RDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQ 202
           RD+VPGD V ++VGD+VPAD+R+   ++  L +D+S LTGE+    K T   P P A N 
Sbjct: 153 RDLVPGDTVCLSVGDRVPADLRLF--EAVDLSIDESSLTGETTPCSKVT--APQPAATNG 208

Query: 203 D---KKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAATEQDKTPLQQKLDEFGEQ 259
           D   + N+ F GT +  GKA G+V  TG  +E G++   M A E  KTPLQ+ +D  G+Q
Sbjct: 209 DLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQ 268

Query: 260 LS----KVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVALAVAAIPEGLPAVI 315
           LS     +I +I +  WL+               +  +  F I+V+LAVAAIPEGLP V+
Sbjct: 269 LSFYSFGIIGIIMLVGWLLG--------------KDILEMFTISVSLAVAAIPEGLPIVV 314

Query: 316 TTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGD 375
           T  LALG  RM KK AIV+ LP VETLGC +VICSDKTGTLT N+M+V  +F  D +  +
Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374

Query: 376 ICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCNDSSLDFNEAKGVYE 435
           +        TG  Y   GEV+ +   V       +  +     +CND+ +  N       
Sbjct: 375 V--------TGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTL----- 421

Query: 436 KVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMS 495
            +G+ TE AL  L  KM +       + K E                    FS ++K M+
Sbjct: 422 -MGKPTEGALIALAMKMGLDGLQQDYIRKAE------------------YPFSSEQKWMA 462

Query: 496 VYC-SPAKSSRAAVGNKMFVKGAPEGVIDRCN-YVRVGTTRVPLTGPVKEKIMAVIKEWG 553
           V C    +  R  +    F+KGA E VI  C  Y   G T   LT   +++ +   ++  
Sbjct: 463 VKCVHRTQQDRPEI---CFMKGAYEQVIKYCTTYQSKGQT---LTLTQQQRDVYQQEKAR 516

Query: 554 TGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGMLDPPRKEVTGSIQL 613
            G   LR LALA+    P+  +               LTF+G+VG++DPPR  V  ++  
Sbjct: 517 MGSAGLRVLALASG---PELGQ---------------LTFLGLVGIIDPPRTGVKEAVTT 558

Query: 614 CRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREACRRA 673
              +G+ + MITGD++ TA+AI  R+G++ +  +    + +G E D + + +  +   + 
Sbjct: 559 LIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ----SVSGEEIDAMDVQQLSQIVPKV 614

Query: 674 CCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASE 732
             F R  P HK KI++ LQ    + AMTGDGVNDA ALK A+IG+AMG +GT V K A++
Sbjct: 615 AVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAAD 674

Query: 733 MVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQL 792
           M+L DD+F TI++A+EEG+ IYNN+K F+R+ +S+++  +  I L   +  P  L  +Q+
Sbjct: 675 MILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQI 734

Query: 793 LWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYVGAATVGAA 852
           LW+N++ DG PA +LG  P D D++ +PPR+ K+ +++  L  + +     +   T    
Sbjct: 735 LWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIVCGT---- 790

Query: 853 AWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTIEMCNA 912
                            L  F +   DN             P   TM  +  V  +M NA
Sbjct: 791 -----------------LFVFWRELRDNV----------ITPRDTTMTFTCFVFFDMFNA 823

Query: 913 LNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQWLMVLK 972
           L+S S+ +S+  +    N     ++  S+    L++Y  PL  +F+  +L +   L +L 
Sbjct: 824 LSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLG 883

Query: 973 ISLPVIGLDEILKFVARN 990
           ++  V  + EI+K V R+
Sbjct: 884 LTSSVCIVAEIIKKVERS 901


>gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo
           sapiens]
          Length = 888

 Score =  449 bits (1156), Expect = e-126
 Identities = 316/952 (33%), Positives = 484/952 (50%), Gaps = 131/952 (13%)

Query: 23  GLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWFEEGE 82
           GL   +V      +G NE    E + LW+  I QF++ L+ +LL +A IS ++  F++  
Sbjct: 45  GLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLLLASAVISVLMHQFDDA- 103

Query: 83  ETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRADRKSVQRIKA 142
                 V   V +LI++  A V   QE  +E ++E L +  P      R  +  ++   A
Sbjct: 104 ------VSITVAILIVVTVAFV---QEYRSEKSLEELSKLVPPECHCVREGK--LEHTLA 152

Query: 143 RDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIKHTEPVPDPRAVNQ 202
           RD+VPGD V ++VGD+VPAD+R+   ++  L +D+S LTGE+    K T   P P A N 
Sbjct: 153 RDLVPGDTVCLSVGDRVPADLRLF--EAVDLSIDESSLTGETTPCSKVT--APQPAATNG 208

Query: 203 D---KKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAATEQDKTPLQQKLDEFGEQ 259
           D   + N+ F GT +  GKA G+V  TG  +E G++   M A E  KTPLQ+ +D  G+Q
Sbjct: 209 DLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAPKTPLQKSMDLLGKQ 268

Query: 260 LS----KVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVALAVAAIPEGLPAVI 315
           LS     +I +I +  WL+               +  +  F I+V+LAVAAIPEGLP V+
Sbjct: 269 LSFYSFGIIGIIMLVGWLLG--------------KDILEMFTISVSLAVAAIPEGLPIVV 314

Query: 316 TTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKVDGD 375
           T  LALG  RM KK AIV+ LP VETLGC +VICSDKTGTLT N+M+V  +F  D +  +
Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374

Query: 376 ICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCNDSSLDFNEAKGVYE 435
           +        TG  Y   GEV+ +   V       +  +     +CND+ +  N       
Sbjct: 375 V--------TGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTL----- 421

Query: 436 KVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKEFTLEFSRDRKSMS 495
            +G+ TE AL  L  KM +       + K E                    FS ++K M+
Sbjct: 422 -MGKPTEGALIALAMKMGLDGLQQDYIRKAE------------------YPFSSEQKWMA 462

Query: 496 VYC-SPAKSSRAAVGNKMFVKGAPEGVIDRCN-YVRVGTTRVPLTGPVKEKIMAVIKEWG 553
           V C    +  R  +    F+KGA E VI  C  Y   G T   LT   +++ +   ++  
Sbjct: 463 VKCVHRTQQDRPEI---CFMKGAYEQVIKYCTTYQSKGQT---LTLTQQQRDVYQQEKAR 516

Query: 554 TGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGMLDPPRKEVTGSIQL 613
            G   LR LALA+    P+  +               LTF+G+VG++DPPR  V  ++  
Sbjct: 517 MGSAGLRVLALASG---PELGQ---------------LTFLGLVGIIDPPRTGVKEAVTT 558

Query: 614 CRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREACRRA 673
              +G+ + MITGD++ TA+AI  R+G++ +  +    + +G E D + + +  +   + 
Sbjct: 559 LIASGVSIKMITGDSQETAVAIASRLGLYSKTSQ----SVSGEEIDAMDVQQLSQIVPKV 614

Query: 674 CCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASE 732
             F R  P HK KI++ LQ    + AMTGDGVNDA ALK A+IG+AMG +GT V K A++
Sbjct: 615 AVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAAD 674

Query: 733 MVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQL 792
           M+L DD+F TI++A+EEG+ IYNN+K F+R+ +S+++  +  I L   +  P  L  +Q+
Sbjct: 675 MILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQI 734

Query: 793 LWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYVGAATVGAA 852
           LW+N++ DG PA +LG  P D D++ +PPR+ K+ +++  L  + +     +   T    
Sbjct: 735 LWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSIIIVCGT---- 790

Query: 853 AWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTIEMCNA 912
                            L  F +   DN             P   TM  +  V  +M NA
Sbjct: 791 -----------------LFVFWRELRDNV----------ITPRDTTMTFTCFVFFDMFNA 823

Query: 913 LNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDL 964
           L+S S+ +S+  +    N     ++  S+    L++Y  PL  +F+  +L +
Sbjct: 824 LSSRSQTKSVFEIGLCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSI 875


>gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo
           sapiens]
          Length = 946

 Score =  441 bits (1134), Expect = e-123
 Identities = 321/977 (32%), Positives = 497/977 (50%), Gaps = 113/977 (11%)

Query: 10  EECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAA 69
           E+    F V   TGL+   V +    +G NE  A+  + +W+  ++QF++ L+ +LL +A
Sbjct: 63  EDLARAFCVDLHTGLSEFSVTQRRLAHGWNEFVADNSEPVWKKYLDQFKNPLILLLLGSA 122

Query: 70  CISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKV 129
            +S +   +E+     TA       +L+++  A +   QE  +E ++E L +  P     
Sbjct: 123 LVSVLTKEYEDAVSIATA-------VLVVVTVAFI---QEYRSEKSLEELTKMVPPECNC 172

Query: 130 YRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIK 189
            R  +  +Q + AR++VPGD+V +++GD++PADIR+  +  T L VD+S  TGE+    K
Sbjct: 173 LREGK--LQHLLARELVPGDVVSLSIGDRIPADIRLTEV--TDLLVDESSFTGEAEPCSK 228

Query: 190 HTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAATEQDKTPL 249
              P+     +     N++F GT +  G+  G+V  TG  ++ G++   M A E  KTPL
Sbjct: 229 TDSPLTGGGDLTT-LSNIVFMGTLVQYGRGQGVVIGTGESSQFGEVFKMMQAEETPKTPL 287

Query: 250 QQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVALAVAAIPE 309
           Q+ +D  G+QL+     I   + LI          G S  +  +  F I V+LAVAAIPE
Sbjct: 288 QKSMDRLGKQLTLFSFGIIGLIMLI----------GWSQGKQLLSMFTIGVSLAVAAIPE 337

Query: 310 GLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFII 369
           GLP V+   L LG  RMAKK  IV+ LP VETLGC SV+CSDKTGTLT N+M+V ++   
Sbjct: 338 GLPIVVMVTLVLGVLRMAKKRVIVKKLPIVETLGCCSVLCSDKTGTLTANEMTVTQLVTS 397

Query: 370 DKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCNDSSLDFNE 429
           D +  ++  +           P  EV+K    V  G+   LVE   +    N++ +  N 
Sbjct: 398 DGLRAEVSGVGYDGQGTVCLLPSKEVIKEFSNVSVGK---LVEAGCVA---NNAVIRKNA 451

Query: 430 AKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKEFTLEFSR 489
                  +G+ TE AL  L  KM++  +D++           NS IR   KKE  + FS 
Sbjct: 452 V------MGQPTEGALMALAMKMDL--SDIK-----------NSYIR---KKE--IPFSS 487

Query: 490 DRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGPVKEKIMAVI 549
           ++K M+V CS     +  +    F+KGA E VI  C     G   +PLT   +++   + 
Sbjct: 488 EQKWMAVKCSLKTEDQEDI---YFMKGALEEVIRYCTMYNNGGIPLPLTP--QQRSFCLQ 542

Query: 550 KEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGMLDPPRKEVTG 609
           +E   G   LR LALA+     +                  LTF+G+VG++DPPR  V  
Sbjct: 543 EEKRMGSLGLRVLALASGPELGR------------------LTFLGLVGIIDPPRVGVKE 584

Query: 610 SIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREA 669
           ++Q+  ++G+ V MITGD   TA+AI R IG+     +    A +G E D +   E  + 
Sbjct: 585 AVQVLSESGVSVKMITGDALETALAIGRNIGLCNGKLQ----AMSGEEVDSVEKGELADR 640

Query: 670 CRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAK 728
             +   F R  P HK KI++ LQ    I AMTGDGVNDA ALK A+IGIAMG +GT V+K
Sbjct: 641 VGKVSVFFRTSPKHKLKIIKALQESGAIVAMTGDGVNDAVALKSADIGIAMGQTGTDVSK 700

Query: 729 TASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALI 788
            A+ M+L DD+FS I+ AVEEG+ I+ N+K F+R+ +S+++  +  I L+    LP  L 
Sbjct: 701 EAANMILVDDDFSAIMNAVEEGKGIFYNIKNFVRFQLSTSISALSLITLSTVFNLPSPLN 760

Query: 789 PVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIGGYVGAAT 848
            +Q+LW+N++ DG PA +LG  P D D   +PPRS ++ ++S  L  + +     + + T
Sbjct: 761 AMQILWINIIMDGPPAQSLGVEPVDKDAFRQPPRSVRDTILSRALILKILMSAAIIISGT 820

Query: 849 VGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTIE 908
           +      F++ ++ P              ED              P   TM  +  V  +
Sbjct: 821 L------FIFWKEMP--------------EDRA----------STPRTTTMTFTCFVFFD 850

Query: 909 MCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQWL 968
           + NAL   S+ + +  +    N   L S+  S+     ++Y+ PL  +F+   L     L
Sbjct: 851 LFNALTCRSQTKLIFEIGFLRNHMFLYSVLGSILGQLAVIYIPPLQRVFQTENLGALDLL 910

Query: 969 MVLKISLPVIGLDEILK 985
            +  ++  V  L E+LK
Sbjct: 911 FLTGLASSVFILSELLK 927


>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapiens]
          Length = 1029

 Score =  365 bits (938), Expect = e-101
 Identities = 297/1044 (28%), Positives = 476/1044 (45%), Gaps = 128/1044 (12%)

Query: 5    HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 64
            H  T EE    + V  T G +  + K  L + G N +        W    +Q       +
Sbjct: 52   HKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVKFCKQLFGGFSLL 111

Query: 65   LLLAACISFVL----AWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120
            L   A + FV      +F E E T        V+ +++I       +QE  +   +E+ K
Sbjct: 112  LWTGAILCFVAYSIQIYFNE-EPTKDNLYLSIVLSVVVIVTGCFSYYQEAKSSKIMESFK 170

Query: 121  EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180
               P+   V R   K   +I  +++V GD+VE+  GD+VPAD+R+++ +    +VD S L
Sbjct: 171  NMVPQQALVIRGGEK--MQINVQEVVLGDLVEIKGGDRVPADLRLISAQGC--KVDNSSL 226

Query: 181  TGESVSVIKHTEPVPDPRAVNQ-DKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQM 239
            TGES    +     PD    N  + +N+ F  TN   G A GIV  TG  T +G+I    
Sbjct: 227  TGESEPQSRS----PDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIASLT 282

Query: 240  AATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIA 299
            +     +TP+  +++ F   ++ V   + V  + +++      + G  W    I+     
Sbjct: 283  SGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSL------LLGYGWLEAIIFL---- 332

Query: 300  VALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTN 359
            + + VA +PEGL A +T CL L  +RMA+KN +V++L +VETLG TS ICSDKTGTLT N
Sbjct: 333  IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 392

Query: 360  QMSVCKM-FIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICA 418
            +M+V  M F +   + D         TG T+                  D    LA I  
Sbjct: 393  RMTVAHMWFDMTVYEAD----TTEEQTGKTFTKSS--------------DTWFMLARIAG 434

Query: 419  LCNDSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVI 475
            LCN +    N+      K    G+A+E+AL   +E+         S S V      N  +
Sbjct: 435  LCNRADFKANQEILPIAKRATTGDASESALLKFIEQ---------SYSSVAEMREKNPKV 485

Query: 476  RQLMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRV 535
             ++         S ++  MS++     S      + + +KGAPE +++ C+   +     
Sbjct: 486  AEIPFN------STNKYQMSIHLREDSSQT----HVLMMKGAPERILEFCSTFLLNGQEY 535

Query: 536  PLTGPVKEKIM-AVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETD-LTF 593
             +   +KE    A ++  G G   L    L    +  K      D+    + +  D L F
Sbjct: 536  SMNDEMKEAFQNAYLELGGLGERVLGFCFLNLPSSFSKGFPFNTDE----INFPMDNLCF 591

Query: 594  VGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAY 653
            VG++ M+DPPR  V  ++  CR AGI+VIM+TGD+  TA AI + +GI  E  E A+   
Sbjct: 592  VGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGTETAEEVA 651

Query: 654  T--------------------GREFDDLPLAEQREACRR--ACCFARVEPSHKSKIVEYL 691
                                 G E  D+   +  +  +      FAR  P  K  IVE  
Sbjct: 652  ARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPEIVFARTSPQQKLIIVEGC 711

Query: 692  QSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEG 750
            Q    + A+TGDGVND+PALKKA+IGIAMG SG+ V+K A++M+L DDNF++IV  VEEG
Sbjct: 712  QRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEG 771

Query: 751  RAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFN 810
            R I++N+K+ I Y ++SN+ E+    +   LG+P  L  + +L ++L TD +PA +L + 
Sbjct: 772  RLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDMVPAISLAYE 831

Query: 811  PPDLDIMDRPPRSPK--------------------EPLISGWLFFRYMAIGGYVGAATVG 850
              + DIM R PR+PK                    + L   + +F  +A  G+     +G
Sbjct: 832  SAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMIQALAGFFTYFVILAENGFRPVDLLG 891

Query: 851  AAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTIEMC 910
                W     +  ++N  + ++  Q T +        C+        T     +V ++  
Sbjct: 892  IRLHW-----EDKYLNDLEDSYGQQWTYEQRKVVEFTCQ--------TAFFVTIVVVQWA 938

Query: 911  NALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQWLMV 970
            + + S +   SL +      + + G +  ++   FL  Y   + +  ++  L +T WL  
Sbjct: 939  DLIISKTRRNSLFQQGMRNKVLIFGILEETLLAAFL-SYTPGMDVALRMYPLKITWWLCA 997

Query: 971  LKISLPVIGLDEILKFVARNYLEG 994
            +  S+ +   DEI K + R + +G
Sbjct: 998  IPYSILIFVYDEIRKLLIRQHPDG 1021


>gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]
          Length = 1020

 Score =  360 bits (925), Expect = 3e-99
 Identities = 300/1039 (28%), Positives = 474/1039 (45%), Gaps = 117/1039 (11%)

Query: 5    HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 64
            H  + +E    + V  + GLT  + +  L + G N L        W     Q       +
Sbjct: 42   HKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 101

Query: 65   LLLAACISFVLAWFE---EGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKE 121
            L + A + F+    +   E E +        V+  ++I       +QE  +   +++ K 
Sbjct: 102  LWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKN 161

Query: 122  YEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILT 181
              P+   V R   K   +I A ++V GD+VEV  GD+VPAD+RI  I S   +VD S LT
Sbjct: 162  MVPQQALVIREGEK--MQINAEEVVVGDLVEVKGGDRVPADLRI--ISSHGCKVDNSSLT 217

Query: 182  GESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAA 241
            GES    +  E   +      + +N+ F  TN   G A GIV  TG  T +G+I    + 
Sbjct: 218  GESEPQTRSPEFTHENPL---ETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASG 274

Query: 242  TEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVA 301
             E  +TP+  +++ F + ++ V   + V+ +++++      + G SW    I+     + 
Sbjct: 275  LEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSL------ILGYSWLEAVIFL----IG 324

Query: 302  LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361
            + VA +PEGL A +T CL L  +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M
Sbjct: 325  IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 384

Query: 362  SVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCN 421
            +V  M+            N+     +T    G       P     +  L  +A +C    
Sbjct: 385  TVAHMWFD----------NQIHEADTTEDQSGATFDKRSPT----WTALSRIAGLCNRAV 430

Query: 422  DSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSV--IRQLM 479
              +   N +    +  G+A+E+AL   +E                   +C SV  +R   
Sbjct: 431  FKAGQENISVSKRDTAGDASESALLKCIEL------------------SCGSVRKMRDRN 472

Query: 480  KKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTG 539
             K   + F+   K          S ++ V   + +KGAPE ++DRC+ + V    +PL  
Sbjct: 473  PKVAEIPFNSTNKYQLSIHEREDSPQSHV---LVMKGAPERILDRCSTILVQGKEIPLDK 529

Query: 540  PVKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETD-LTFVGVVG 598
             +++       E G   +  R L     + P  +           L + T+ L FVG++ 
Sbjct: 530  EMQDAFQNAYMELGGLGE--RVLGFCQLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMS 587

Query: 599  MLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGE-NEEVADRAYT--- 654
            M+DPPR  V  ++  CR AGI+VIM+TGD+  TA AI + +GI  E NE V D A     
Sbjct: 588  MIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNI 647

Query: 655  ----------------GREFDDLPLAEQREACRR--ACCFARVEPSHKSKIVEYLQSYDE 696
                            G +  D+   +  E  +      FAR  P  K  IVE  Q    
Sbjct: 648  PMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGA 707

Query: 697  ITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYN 755
            I A+TGDGVND+PALKKA+IGIAMG SG+ V+K A++M+L DDNF++IV  VEEGR I++
Sbjct: 708  IVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFD 767

Query: 756  NMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLD 815
            N+K+ I Y ++SN+ E+    L     +P  L  V +L ++L TD +PA +L +   + D
Sbjct: 768  NLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEAAESD 827

Query: 816  IMDRPPRSPK------EPLIS------GWL-----FFRYMAI---GGYVGAATVGAAAWW 855
            IM R PR+ +      E LIS      G +     FF Y  I    G++ +  +G    W
Sbjct: 828  IMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDW 887

Query: 856  FLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTIEMCNALNS 915
                 D   +N  + ++  + T +        C         T   + +V ++  + +  
Sbjct: 888  -----DDRTMNDLEDSYGQEWTYEQRKVVEFTCH--------TAFFASIVVVQWADLIIC 934

Query: 916  LSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQWLMVLKISL 975
             +   S+ +      I + G +    +L   + Y   + +  ++  L +T W      SL
Sbjct: 935  KTRRNSVFQQGMKNKILIFG-LLEETALAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSL 993

Query: 976  PVIGLDEILKFVARNYLEG 994
             +   DE+ K + R Y  G
Sbjct: 994  LIFIYDEVRKLILRRYPGG 1012


>gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]
          Length = 1013

 Score =  358 bits (918), Expect = 2e-98
 Identities = 297/1042 (28%), Positives = 482/1042 (46%), Gaps = 132/1042 (12%)

Query: 5    HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 64
            H  + EE    +      GLT  + +  L + G N L        W     Q       +
Sbjct: 34   HKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 93

Query: 65   LLLAACISFVLAWFEEGEETITAFVEPF---VILLILIANAIVGVWQERNAENAIEALKE 121
            L + A + F+    + G E   +    +   V+  ++I       +QE  +   +E+ K 
Sbjct: 94   LWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKN 153

Query: 122  YEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILT 181
              P+   V R   K   ++ A ++V GD+VE+  GD+VPAD+RI++      +VD S LT
Sbjct: 154  MVPQQALVIREGEK--MQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGC--KVDNSSLT 209

Query: 182  GESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAA 241
            GES    +  +   D      + +N+ F  TN   G A G+V  TG  T +G+I    + 
Sbjct: 210  GESEPQTRSPDCTHDNPL---ETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASG 266

Query: 242  TEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVA 301
             E  KTP+  +++ F + ++ V   + V+ +++++      + G +W    I+     + 
Sbjct: 267  LEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSL------ILGYTWLEAVIFL----IG 316

Query: 302  LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361
            + VA +PEGL A +T CL L  +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M
Sbjct: 317  IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 376

Query: 362  SVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCN 421
            +V  M+  +++       ++   +G+++                     V L+ I  LCN
Sbjct: 377  TVAHMWFDNQIHEADTTEDQ---SGTSFDKSSHTW--------------VALSHIAGLCN 419

Query: 422  DSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQL 478
             +     +      K    G+A+E+AL                L  +E ++    ++R+ 
Sbjct: 420  RAVFKGGQDNIPVLKRDVAGDASESAL----------------LKCIELSSGSVKLMRER 463

Query: 479  MKKEFTLEFSRDRK-SMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPL 537
             KK   + F+   K  +S++ +   +    +   + +KGAPE ++DRC+ + +     PL
Sbjct: 464  NKKVAEIPFNSTNKYQLSIHETEDPNDNRYL---LVMKGAPERILDRCSTILLQGKEQPL 520

Query: 538  TGPVKEKIM-AVIKEWGTGRDTLR-CLALATRDTPPKREEMVLDDSARFLEYETD-LTFV 594
               +KE    A ++  G G   L  C      +  PK      DD    + + TD L FV
Sbjct: 521  DEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDCDD----VNFTTDNLCFV 576

Query: 595  GVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGE-NEEVADRAY 653
            G++ M+DPPR  V  ++  CR AGI+VIM+TGD+  TA AI + +GI  E NE V D A 
Sbjct: 577  GLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAA 636

Query: 654  TGREFDDLPLAEQREACRRACC-------------------------FARVEPSHKSKIV 688
                  ++P+++      +AC                          FAR  P  K  IV
Sbjct: 637  RL----NIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIV 692

Query: 689  EYLQSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAV 747
            E  Q    I A+TGDGVND+PALKKA+IG+AMG +G+ V+K A++M+L DDNF++IV  V
Sbjct: 693  EGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGV 752

Query: 748  EEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATAL 807
            EEGR I++N+K+ I Y ++SN+ E+    L     +P  L  + +L ++L TD +PA +L
Sbjct: 753  EEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISL 812

Query: 808  GFNPPDLDIMDRPPRSPK------EPLIS------GWL-----FFRYMAI---GGYVGAA 847
             +   + DIM R PR+P+      E LIS      G +     FF Y  I    G++   
Sbjct: 813  AYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQALGGFFSYFVILAENGFLPGN 872

Query: 848  TVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTI 907
             VG    W     D   VN  + ++  Q T +        C         T     +V +
Sbjct: 873  LVGIRLNW-----DDRTVNDLEDSYGQQWTYEQRKVVEFTCH--------TAFFVSIVVV 919

Query: 908  EMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQW 967
            +  + +   +   S+ +      I + G +    +L   + Y   + +  ++  L  + W
Sbjct: 920  QWADLIICKTRRNSVFQQGMKNKILIFG-LFEETALAAFLSYCPGMDVALRMYPLKPSWW 978

Query: 968  LMVLKISLPVIGLDEILKFVAR 989
                  S  +   DEI K + R
Sbjct: 979  FCAFPYSFLIFVYDEIRKLILR 1000


>gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]
          Length = 1035

 Score =  356 bits (913), Expect = 7e-98
 Identities = 303/1033 (29%), Positives = 476/1033 (46%), Gaps = 113/1033 (10%)

Query: 5    HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 64
            H  +  E    +  S T GL+       L + G N L    G   +     Q    L  +
Sbjct: 55   HQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVKFARQLAGGLQCL 114

Query: 65   LLLAACISFVLAWFEEGEETITAFVEPFV---ILLILIANAIVGVWQERNAENAIEALKE 121
            + +AA I  +    +  E  +T     ++   ++ +++     G +QE  + N I + K 
Sbjct: 115  MWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQEFKSTNIIASFKN 174

Query: 122  YEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILT 181
              P+   V R   K   +I A  +V GD+VE+  GD+VPADIRILA +    +VD S LT
Sbjct: 175  LVPQQATVIRDGDKF--QINADQLVVGDLVEMKGGDRVPADIRILAAQGC--KVDNSSLT 230

Query: 182  GESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAA 241
            GES    +  E   +      + +N+ F  T    G   G+V  TG  T IG+I    + 
Sbjct: 231  GESEPQTRSPECTHESPL---ETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIASLASG 287

Query: 242  TEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVA 301
             E +KTP+  +++ F + ++ +  L     +++ +        G ++ R  +++    +A
Sbjct: 288  VENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAM------CIGYTFLRAMVFF----MA 337

Query: 302  LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361
            + VA +PEGL A +T CL+L  +R+A KN +V++L +VETLG TSVICSDKTGTLT N+M
Sbjct: 338  IVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRM 397

Query: 362  SVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCN 421
            +V  ++  + +       ++   +G T+    E  +               L  +  LCN
Sbjct: 398  TVSHLWFDNHIHTADTTEDQ---SGQTFDQSSETWR--------------ALCRVLTLCN 440

Query: 422  DSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVER-ANACNSVIRQ 477
             ++    +      K   +G+A+ETAL    E      T   ++   +R    C      
Sbjct: 441  RAAFKSGQDAVPVPKRIVIGDASETALLKFSEL-----TLGNAMGYRDRFPKVCEIPFNS 495

Query: 478  LMKKEF---TLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTR 534
              K +    TLE  RD + + V                 +KGAPE V++RC+ + +    
Sbjct: 496  TNKFQLSIHTLEDPRDPRHLLV-----------------MKGAPERVLERCSSILIKGQE 538

Query: 535  VPLTGPVKEKIM-AVIKEWGTGRDTLRC--LALATRDTPPKREEMVLDDSARFLEYETDL 591
            +PL    +E    A +   G G   L    L L  +D PP       D  A      + L
Sbjct: 539  LPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPG---YAFDVEAMNFP-SSGL 594

Query: 592  TFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGEN----EE 647
             F G+V M+DPPR  V  ++  CR AGIRVIM+TGD+  TA AI   +GI  E     E+
Sbjct: 595  CFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASVGIISEGSETVED 654

Query: 648  VADR----------------AYTGREFDDLPLAEQREACRR--ACCFARVEPSHKSKIVE 689
            +A R                   G +  D+  +E  EA R      FAR  P  K  IVE
Sbjct: 655  IAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFARTSPQQKLVIVE 714

Query: 690  YLQSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVE 748
              Q    I A+TGDGVND+PALKKA+IG+AMG +G+  AK A++M+L DDNF++IV  VE
Sbjct: 715  SCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILLDDNFASIVTGVE 774

Query: 749  EGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALG 808
            +GR I++N+K+ I Y ++ N+ E+    +   + +P  L  + +L++ L TD  P+ +L 
Sbjct: 775  QGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIELCTDIFPSVSLA 834

Query: 809  FNPPDLDIMDRPPRSPK------EPLISGWLFFRYMAIGGYVGAA---TVGAAAWWFLYA 859
            +   + DIM   PR+PK      EPL + + +F+  AI  + G     T  A   WF   
Sbjct: 835  YEKAESDIMHLRPRNPKRDRLVNEPL-AAYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLL 893

Query: 860  EDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTIEMCNALNSL--- 916
              G    +    H +Q  +D+   E    +     +  T      ++IE+C   + L   
Sbjct: 894  CVGLRAQWED--HHLQDLQDSYGQEWTFGQ--RLYQQYTCYTVFFISIEVCQIADVLIRK 949

Query: 917  SENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQWLMVLKISLP 976
            +   S  +   + N  L+ +I   + +   + Y   +P IF    +    WL+ L   + 
Sbjct: 950  TRRLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLVPLPYGIL 1009

Query: 977  VIGLDEILKFVAR 989
            +   DEI K   R
Sbjct: 1010 IFVYDEIRKLGVR 1022


>gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapiens]
          Length = 1023

 Score =  355 bits (911), Expect = 1e-97
 Identities = 304/1047 (29%), Positives = 482/1047 (46%), Gaps = 142/1047 (13%)

Query: 5    HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 64
            H  + +E    +G   + GLT  +    L + G N L        W     Q       +
Sbjct: 44   HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSML 103

Query: 65   LLLAACISF----VLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120
            L + A + F    + A  EE  +    ++   V+  ++I       +QE  +   +E+ K
Sbjct: 104  LWIGAILCFLAYSIQAATEEEPQNDNLYLG-VVLSAVVIITGCFSYYQEAKSSKIMESFK 162

Query: 121  EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180
               P+   V R   K    I A ++V GD+VEV  GD++PAD+RI  I +   +VD S L
Sbjct: 163  NMVPQQALVIRNGEK--MSINAEEVVVGDLVEVKGGDRIPADLRI--ISANGCKVDNSSL 218

Query: 181  TGESVSVIKHTEPVPDPRAVNQ-DKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQM 239
            TGES    +     PD    N  + +N+ F  TN   G A GIV  TG  T +G+I    
Sbjct: 219  TGESEPQTRS----PDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA 274

Query: 240  AATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIA 299
            +  E  +TP+  +++ F   ++ V   + V+ +++++      +   +W    I+     
Sbjct: 275  SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSL------ILEYTWLEAVIFL---- 324

Query: 300  VALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTN 359
            + + VA +PEGL A +T CL L  +RMA+KN +V++L +VETLG TS ICSDKTGTLT N
Sbjct: 325  IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 384

Query: 360  QMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGL-VELATICA 418
            +M+V  M+  +++                   E +  +N   V   +     + L+ I  
Sbjct: 385  RMTVAHMWFDNQIH------------------EADTTENQSGVSFDKTSATWLALSRIAG 426

Query: 419  LCNDSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSV- 474
            LCN +    N+      K    G+A+E+AL   +E                    C SV 
Sbjct: 427  LCNRAVFQANQENLPILKRAVAGDASESALLKCIEL------------------CCGSVK 468

Query: 475  -IRQLMKKEFTLEFSRDRK-SMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGT 532
             +R+   K   + F+   K  +S++ +P  S    +   + +KGAPE ++DRC+ + +  
Sbjct: 469  EMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHL---LVMKGAPERILDRCSSILLHG 525

Query: 533  TRVPLTGPVKEKIM-AVIKEWGTGRDTLRCLALATRDTP-PKREEMVLDDSARFLEYETD 590
               PL   +K+    A ++  G G   L    L   D   P+  +   DD    + +  D
Sbjct: 526  KEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDD----VNFPID 581

Query: 591  -LTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGE-NEEV 648
             L FVG++ M+DPPR  V  ++  CR AGI+VIM+TGD+  TA AI + +GI  E NE V
Sbjct: 582  NLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETV 641

Query: 649  ADRAYTGREFDDLPLAEQREACRRACC-------------------------FARVEPSH 683
             D A       ++P+++      +AC                          FAR  P  
Sbjct: 642  EDIAARL----NIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQ 697

Query: 684  KSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFST 742
            K  IVE  Q    I A+TGDGVND+PALKKA+IG+AMG +G+ V+K A++M+L DDNF++
Sbjct: 698  KLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFAS 757

Query: 743  IVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGL 802
            IV  VEEGR I++N+K+ I Y ++SN+ E+    +     +P  L  V +L ++L TD +
Sbjct: 758  IVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMV 817

Query: 803  PATALGFNPPDLDIMDRPPRSPK------EPLIS------GWL-----FFRYMAI---GG 842
            PA +L +   + DIM R PR+PK      E LIS      G +     FF Y  I    G
Sbjct: 818  PAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENG 877

Query: 843  YVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALS 902
            ++    +G    W     D   +N  + ++  Q T +        C         T    
Sbjct: 878  FLPIHLLGLRVDW-----DDRWINDVEDSYGQQWTYEQRKIVEFTCH--------TAFFV 924

Query: 903  VLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRAL 962
             +V ++  + +   +   S+ +      I + G +    +L   + Y   + +  ++  L
Sbjct: 925  SIVVVQWADLVICKTRRNSVFQQGMKNKILIFG-LFEETALAAFLSYCPGMGVALRMYPL 983

Query: 963  DLTQWLMVLKISLPVIGLDEILKFVAR 989
              T W      SL +   DE+ K + R
Sbjct: 984  KPTWWFCAFPYSLLIFVYDEVRKLIIR 1010


>gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo
           sapiens]
          Length = 992

 Score =  355 bits (911), Expect = 1e-97
 Identities = 304/1047 (29%), Positives = 482/1047 (46%), Gaps = 142/1047 (13%)

Query: 5   HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 64
           H  + +E    +G   + GLT  +    L + G N L        W     Q       +
Sbjct: 13  HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSML 72

Query: 65  LLLAACISF----VLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120
           L + A + F    + A  EE  +    ++   V+  ++I       +QE  +   +E+ K
Sbjct: 73  LWIGAILCFLAYSIQAATEEEPQNDNLYLG-VVLSAVVIITGCFSYYQEAKSSKIMESFK 131

Query: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180
              P+   V R   K    I A ++V GD+VEV  GD++PAD+RI  I +   +VD S L
Sbjct: 132 NMVPQQALVIRNGEK--MSINAEEVVVGDLVEVKGGDRIPADLRI--ISANGCKVDNSSL 187

Query: 181 TGESVSVIKHTEPVPDPRAVNQ-DKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQM 239
           TGES    +     PD    N  + +N+ F  TN   G A GIV  TG  T +G+I    
Sbjct: 188 TGESEPQTRS----PDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA 243

Query: 240 AATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIA 299
           +  E  +TP+  +++ F   ++ V   + V+ +++++      +   +W    I+     
Sbjct: 244 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSL------ILEYTWLEAVIFL---- 293

Query: 300 VALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTN 359
           + + VA +PEGL A +T CL L  +RMA+KN +V++L +VETLG TS ICSDKTGTLT N
Sbjct: 294 IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 353

Query: 360 QMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGL-VELATICA 418
           +M+V  M+  +++                   E +  +N   V   +     + L+ I  
Sbjct: 354 RMTVAHMWFDNQIH------------------EADTTENQSGVSFDKTSATWLALSRIAG 395

Query: 419 LCNDSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSV- 474
           LCN +    N+      K    G+A+E+AL   +E                    C SV 
Sbjct: 396 LCNRAVFQANQENLPILKRAVAGDASESALLKCIEL------------------CCGSVK 437

Query: 475 -IRQLMKKEFTLEFSRDRK-SMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGT 532
            +R+   K   + F+   K  +S++ +P  S    +   + +KGAPE ++DRC+ + +  
Sbjct: 438 EMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHL---LVMKGAPERILDRCSSILLHG 494

Query: 533 TRVPLTGPVKEKIM-AVIKEWGTGRDTLRCLALATRDTP-PKREEMVLDDSARFLEYETD 590
              PL   +K+    A ++  G G   L    L   D   P+  +   DD    + +  D
Sbjct: 495 KEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDD----VNFPID 550

Query: 591 -LTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGE-NEEV 648
            L FVG++ M+DPPR  V  ++  CR AGI+VIM+TGD+  TA AI + +GI  E NE V
Sbjct: 551 NLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETV 610

Query: 649 ADRAYTGREFDDLPLAEQREACRRACC-------------------------FARVEPSH 683
            D A       ++P+++      +AC                          FAR  P  
Sbjct: 611 EDIAARL----NIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQ 666

Query: 684 KSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFST 742
           K  IVE  Q    I A+TGDGVND+PALKKA+IG+AMG +G+ V+K A++M+L DDNF++
Sbjct: 667 KLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFAS 726

Query: 743 IVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGL 802
           IV  VEEGR I++N+K+ I Y ++SN+ E+    +     +P  L  V +L ++L TD +
Sbjct: 727 IVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMV 786

Query: 803 PATALGFNPPDLDIMDRPPRSPK------EPLIS------GWL-----FFRYMAI---GG 842
           PA +L +   + DIM R PR+PK      E LIS      G +     FF Y  I    G
Sbjct: 787 PAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENG 846

Query: 843 YVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALS 902
           ++    +G    W     D   +N  + ++  Q T +        C         T    
Sbjct: 847 FLPIHLLGLRVDW-----DDRWINDVEDSYGQQWTYEQRKIVEFTCH--------TAFFV 893

Query: 903 VLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRAL 962
            +V ++  + +   +   S+ +      I + G +    +L   + Y   + +  ++  L
Sbjct: 894 SIVVVQWADLVICKTRRNSVFQQGMKNKILIFG-LFEETALAAFLSYCPGMGVALRMYPL 952

Query: 963 DLTQWLMVLKISLPVIGLDEILKFVAR 989
             T W      SL +   DE+ K + R
Sbjct: 953 KPTWWFCAFPYSLLIFVYDEVRKLIIR 979


>gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]
          Length = 1023

 Score =  355 bits (911), Expect = 1e-97
 Identities = 304/1047 (29%), Positives = 482/1047 (46%), Gaps = 142/1047 (13%)

Query: 5    HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 64
            H  + +E    +G   + GLT  +    L + G N L        W     Q       +
Sbjct: 44   HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSML 103

Query: 65   LLLAACISF----VLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120
            L + A + F    + A  EE  +    ++   V+  ++I       +QE  +   +E+ K
Sbjct: 104  LWIGAILCFLAYSIQAATEEEPQNDNLYLG-VVLSAVVIITGCFSYYQEAKSSKIMESFK 162

Query: 121  EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180
               P+   V R   K    I A ++V GD+VEV  GD++PAD+RI  I +   +VD S L
Sbjct: 163  NMVPQQALVIRNGEK--MSINAEEVVVGDLVEVKGGDRIPADLRI--ISANGCKVDNSSL 218

Query: 181  TGESVSVIKHTEPVPDPRAVNQ-DKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQM 239
            TGES    +     PD    N  + +N+ F  TN   G A GIV  TG  T +G+I    
Sbjct: 219  TGESEPQTRS----PDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA 274

Query: 240  AATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIA 299
            +  E  +TP+  +++ F   ++ V   + V+ +++++      +   +W    I+     
Sbjct: 275  SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSL------ILEYTWLEAVIFL---- 324

Query: 300  VALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTN 359
            + + VA +PEGL A +T CL L  +RMA+KN +V++L +VETLG TS ICSDKTGTLT N
Sbjct: 325  IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 384

Query: 360  QMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGL-VELATICA 418
            +M+V  M+  +++                   E +  +N   V   +     + L+ I  
Sbjct: 385  RMTVAHMWFDNQIH------------------EADTTENQSGVSFDKTSATWLALSRIAG 426

Query: 419  LCNDSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSV- 474
            LCN +    N+      K    G+A+E+AL   +E                    C SV 
Sbjct: 427  LCNRAVFQANQENLPILKRAVAGDASESALLKCIEL------------------CCGSVK 468

Query: 475  -IRQLMKKEFTLEFSRDRK-SMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGT 532
             +R+   K   + F+   K  +S++ +P  S    +   + +KGAPE ++DRC+ + +  
Sbjct: 469  EMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHL---LVMKGAPERILDRCSSILLHG 525

Query: 533  TRVPLTGPVKEKIM-AVIKEWGTGRDTLRCLALATRDTP-PKREEMVLDDSARFLEYETD 590
               PL   +K+    A ++  G G   L    L   D   P+  +   DD    + +  D
Sbjct: 526  KEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDD----VNFPID 581

Query: 591  -LTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGE-NEEV 648
             L FVG++ M+DPPR  V  ++  CR AGI+VIM+TGD+  TA AI + +GI  E NE V
Sbjct: 582  NLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETV 641

Query: 649  ADRAYTGREFDDLPLAEQREACRRACC-------------------------FARVEPSH 683
             D A       ++P+++      +AC                          FAR  P  
Sbjct: 642  EDIAARL----NIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQ 697

Query: 684  KSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFST 742
            K  IVE  Q    I A+TGDGVND+PALKKA+IG+AMG +G+ V+K A++M+L DDNF++
Sbjct: 698  KLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFAS 757

Query: 743  IVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGL 802
            IV  VEEGR I++N+K+ I Y ++SN+ E+    +     +P  L  V +L ++L TD +
Sbjct: 758  IVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMV 817

Query: 803  PATALGFNPPDLDIMDRPPRSPK------EPLIS------GWL-----FFRYMAI---GG 842
            PA +L +   + DIM R PR+PK      E LIS      G +     FF Y  I    G
Sbjct: 818  PAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENG 877

Query: 843  YVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALS 902
            ++    +G    W     D   +N  + ++  Q T +        C         T    
Sbjct: 878  FLPIHLLGLRVDW-----DDRWINDVEDSYGQQWTYEQRKIVEFTCH--------TAFFV 924

Query: 903  VLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRAL 962
             +V ++  + +   +   S+ +      I + G +    +L   + Y   + +  ++  L
Sbjct: 925  SIVVVQWADLVICKTRRNSVFQQGMKNKILIFG-LFEETALAAFLSYCPGMGVALRMYPL 983

Query: 963  DLTQWLMVLKISLPVIGLDEILKFVAR 989
              T W      SL +   DE+ K + R
Sbjct: 984  KPTWWFCAFPYSLLIFVYDEVRKLIIR 1010


>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
          Length = 1039

 Score =  333 bits (855), Expect = 4e-91
 Identities = 273/898 (30%), Positives = 431/898 (47%), Gaps = 104/898 (11%)

Query: 5   HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNEL-PAEEGKTLWELVIEQFE--DLL 61
           H  +  E    +G     GL+  +    L + G N L P ++   + + + +      +L
Sbjct: 59  HKLSNRELEEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSIL 118

Query: 62  VRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKE 121
           + +      I++ + +  +   ++       V+ L++I   I   +QE  + N + +  +
Sbjct: 119 LWVGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNK 178

Query: 122 YEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILT 181
             P+   V R   K    I +  +V GDIVEV  GD++PADIR+L+  S   RVD S LT
Sbjct: 179 MIPQQALVIRDSEKKT--IPSEQLVVGDIVEVKGGDQIPADIRVLS--SQGCRVDNSSLT 234

Query: 182 GESV-----SVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIR 236
           GES      S   H  P+        + KN+ F  T    G   G+V  TG  T IG I 
Sbjct: 235 GESEPQPRSSEFTHENPL--------ETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIA 286

Query: 237 DQMAATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYF 296
              +    +KTP+  +++ F   ++ V   I +  ++I +          S     +   
Sbjct: 287 SLASGVGNEKTPIAIEIEHFVHIVAGVAVSIGILFFIIAV----------SLKYQVLDSI 336

Query: 297 KIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTL 356
              + + VA +PEGL A +T  L+L  +RMAKKN +V++L +VETLG TS+ICSDKTGTL
Sbjct: 337 IFLIGIIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTL 396

Query: 357 TTNQMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATI 416
           T N+M+V  ++            N+  +  ++     +V                 L+ I
Sbjct: 397 TQNRMTVAHLWFD----------NQIFVADTSEDHSNQVFDQSSRT-------WASLSKI 439

Query: 417 CALCNDSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVERANACNS 473
             LCN +     +      K   +G+A+ETAL    E   V   DV  + K  R      
Sbjct: 440 ITLCNRAEFKPGQENVPIMKKAVIGDASETALLKFSE---VILGDVMEIRKRNR------ 490

Query: 474 VIRQLMKKEFTLEFSRDRK-SMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGT 532
                  K   + F+   K  +S++       +  +   M +KGAPE ++++C+ + +  
Sbjct: 491 -------KVAEIPFNSTNKFQLSIHEMDDPHGKRFL---MVMKGAPERILEKCSTIMING 540

Query: 533 TRVPLT-GPVKEKIMAVIKEWGTGRDTLR-CLALATRDTPPKREEMVLDDSARFLEYET- 589
              PL     K    A ++  G G   L  C      D  P+     +D     + + T 
Sbjct: 541 EEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFDIDA----MNFPTS 596

Query: 590 DLTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEE-V 648
           +L FVG++ M+DPPR  V  ++  CR AGI+VIM+TGD+  TA AI + +GI   N E V
Sbjct: 597 NLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETV 656

Query: 649 ADRAY-------------------TGREFDDLPLAEQRE--ACRRACCFARVEPSHKSKI 687
            D A+                   TG E  D+   +  E  A  +   FAR  P  K  I
Sbjct: 657 EDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFARTSPQQKLII 716

Query: 688 VEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAA 746
           VE  Q  D + A+TGDGVND+PALKKA+IGIAMG +G+  AK A++MVL DDNF++IV  
Sbjct: 717 VEGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTG 776

Query: 747 VEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATA 806
           VEEGR I++N+K+ I Y ++ N+ E+    +   +GLP  +  + +L+++L TD +P+ A
Sbjct: 777 VEEGRLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIA 836

Query: 807 LGFNPPDLDIMDRPPR-SPKEPLISGWL-FFRYMAIGGYVGAATVGAAAWWFLYAEDG 862
           L +   + DIM+R PR   K+ L++  L  + Y+ IG  +  A      ++ +YA++G
Sbjct: 837 LAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIG--LMQALGAFLVYFTVYAQEG 892


>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo
           sapiens]
          Length = 1198

 Score =  299 bits (766), Expect = 8e-81
 Identities = 271/895 (30%), Positives = 405/895 (45%), Gaps = 148/895 (16%)

Query: 23  GLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWF---- 78
           G  PD  KR  + +G N +P ++ KT  +LV E  +D+ + IL +AA IS  L+++    
Sbjct: 70  GTAPDLEKRK-QIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPG 128

Query: 79  -------------EEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPE 125
                        E+  E    ++E   ILL +I   +V  + + + E     L+    +
Sbjct: 129 EGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQ 188

Query: 126 MGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESV 185
             K        V +I   +IV GDI +V  GD +PAD   L I+   L++D+S LTGES 
Sbjct: 189 EQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADG--LFIQGNDLKIDESSLTGESD 246

Query: 186 SVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIG------------ 233
            V K             DK  ML SGT++  G    +V   GV ++ G            
Sbjct: 247 QVRKSV-----------DKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEE 295

Query: 234 --------KIRDQMAATE----------------------QDKTPLQQKLDEFGEQLSK- 262
                   K +D  AA E                      ++K+ LQ KL +   Q+ K 
Sbjct: 296 EEKKDKKAKQQDGAAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKA 355

Query: 263 --VISLICVAVWLINIGHFNDPVHGGSWFRGA--------IYYFKIAVALAVAAIPEGLP 312
             V+S I V + ++        V+   W            + +F I V + V A+PEGLP
Sbjct: 356 GLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLP 415

Query: 313 AVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCKMFIIDKV 372
             +T  LA   ++M K N +VR L + ET+G  + ICSDKTGTLTTN+M+V + ++    
Sbjct: 416 LAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYV---- 471

Query: 373 DGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCNDSSLDFNEAKG 432
            GD+                 + + +   +     + L+    I +      L   +   
Sbjct: 472 -GDV---------------HYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGA 515

Query: 433 VYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKEFTLEFSRDRK 492
           +  +VG  TE  L   V  +      VRS    E+           + K +T  F+  RK
Sbjct: 516 LPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEK-----------LYKVYT--FNSVRK 562

Query: 493 SMSVYCS-PAKSSRAAVGNKMFVKGAPEGVIDRCNYVR--VGTTRVPLTGPVKEKIMAVI 549
           SMS     P +S R      M+ KGA E V+ +C  +    G  RV       E +  VI
Sbjct: 563 SMSTVIKLPDESFR------MYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVI 616

Query: 550 KEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGMLDPPRKEVTG 609
           +      D LR + +A RD P   E     D     +   +LT + VVG+ DP R EV  
Sbjct: 617 EPMAC--DGLRTICVAYRDFPSSPEP----DWDNENDILNELTCICVVGIEDPVRPEVPE 670

Query: 610 SIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDDLPLAEQREA 669
           +I+ C+ AGI V M+TGDN  TA AI  + GI    E+       G+EF+     E+ E 
Sbjct: 671 AIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFL--CLEGKEFNRRIRNEKGEI 728

Query: 670 CRRAC--------CFARVEPSHKSKIVEYL-----QSYDEITAMTGDGVNDAPALKKAEI 716
            +             AR  P+ K  +V+ +         ++ A+TGDG ND PALKKA++
Sbjct: 729 EQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADV 788

Query: 717 GIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCI 775
           G AMG +GT VAK AS+++L DDNFS+IV AV  GR +Y+++ +F+++ ++ NV  V+  
Sbjct: 789 GFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVA 848

Query: 776 FLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLIS 830
           F  A +     L  VQ+LWVNL+ D   + AL   PP   ++ R P    +PLIS
Sbjct: 849 FTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLIS 903


>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
           sapiens]
          Length = 1170

 Score =  295 bits (754), Expect = 2e-79
 Identities = 265/904 (29%), Positives = 411/904 (45%), Gaps = 159/904 (17%)

Query: 26  PDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWF------- 78
           P  +++  + +G N +P ++ KT  ELV E  +D+ + IL +AA IS VL+++       
Sbjct: 70  PADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEEN 129

Query: 79  ----------EEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGK 128
                     E+  E    ++E   IL  +I   +V  + + + E     L+    +  K
Sbjct: 130 ELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQK 189

Query: 129 VYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVI 188
                   + ++   +IV GDI +V  GD +PAD   + I+   L++D+S LTGES  V 
Sbjct: 190 FSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADG--ILIQGNDLKIDESSLTGESDHVK 247

Query: 189 KHTEPVPDPRAVNQDKKNMLFSGTNIAAGK------ALGIVATTGV-------------- 228
           K           + DK  ML SGT++  G       A+G+ + TG+              
Sbjct: 248 K-----------SLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGE 296

Query: 229 ----GTEIGKIRDQMAATEQD-------------------------------KTPLQQKL 253
               G + G   ++  A  QD                               K+ LQ KL
Sbjct: 297 KKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKL 356

Query: 254 DEFGEQLSKVISLICVAVWLINIGHF---NDPVHGGSWFRGA--------IYYFKIAVAL 302
                Q+ K   L+      I I +F   N  ++   W            + +F I + +
Sbjct: 357 TRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITV 416

Query: 303 AVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMS 362
            V A+PEGLP  +T  LA   ++M K N +VR L + ET+G  + ICSDKTGTLT N+M+
Sbjct: 417 LVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMT 476

Query: 363 VCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCND 422
           V + +I                 G  +  +   + +     P   D +V   +I +    
Sbjct: 477 VVQAYI-----------------GGIHYRQ---IPSPDVFLPKVLDLIVNGISINSAYTS 516

Query: 423 SSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKE 482
             L   +  G+  +VG  TE AL   V       TD++   +  R    N V  + + K 
Sbjct: 517 KILPPEKEGGLPRQVGNKTECALLGFV-------TDLKQDYQAVR----NEVPEEKLYKV 565

Query: 483 FTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYV--RVGTTRVPLTGP 540
           +T  F+  RKSMS             G +M+ KGA E ++ +CN +  R G   VP    
Sbjct: 566 YT--FNSVRKSMSTVIRNPNG-----GFRMYSKGASEIILRKCNRILDRKGEA-VPFKNK 617

Query: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML 600
            ++ ++  + E     D LR + +A RD      E   D+    L   T+LT + VVG+ 
Sbjct: 618 DRDDMVRTVIE-PMACDGLRTICIAYRDFDDT--EPSWDNENEIL---TELTCIAVVGIE 671

Query: 601 DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD 660
           DP R EV  +I  C+ AGI V M+TGDN  TA AI  + GI    ++       G+EF+ 
Sbjct: 672 DPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL--CLEGKEFNR 729

Query: 661 LPLAEQREACRRAC--------CFARVEPSHKSKIVEYL-----QSYDEITAMTGDGVND 707
           L   E+ E  +             AR  P+ K  +V+ +       + ++ A+TGDG ND
Sbjct: 730 LIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTND 789

Query: 708 APALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLIS 766
            PALKKA++G AMG +GT VAK AS+++L DDNF++IV AV  GR +Y+++ +F+++ ++
Sbjct: 790 GPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLT 849

Query: 767 SNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKE 826
            NV  V+  F  A +     L  VQ+LWVNL+ D   + AL   PP   ++ R P    +
Sbjct: 850 VNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNK 909

Query: 827 PLIS 830
           PLIS
Sbjct: 910 PLIS 913


>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
           sapiens]
          Length = 1205

 Score =  295 bits (754), Expect = 2e-79
 Identities = 265/904 (29%), Positives = 411/904 (45%), Gaps = 159/904 (17%)

Query: 26  PDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWF------- 78
           P  +++  + +G N +P ++ KT  ELV E  +D+ + IL +AA IS VL+++       
Sbjct: 70  PADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLSFYRPAGEEN 129

Query: 79  ----------EEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGK 128
                     E+  E    ++E   IL  +I   +V  + + + E     L+    +  K
Sbjct: 130 ELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQK 189

Query: 129 VYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVI 188
                   + ++   +IV GDI +V  GD +PAD   + I+   L++D+S LTGES  V 
Sbjct: 190 FSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADG--ILIQGNDLKIDESSLTGESDHVK 247

Query: 189 KHTEPVPDPRAVNQDKKNMLFSGTNIAAGK------ALGIVATTGV-------------- 228
           K           + DK  ML SGT++  G       A+G+ + TG+              
Sbjct: 248 K-----------SLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGE 296

Query: 229 ----GTEIGKIRDQMAATEQD-------------------------------KTPLQQKL 253
               G + G   ++  A  QD                               K+ LQ KL
Sbjct: 297 KKKKGKKQGVPENRNKAKTQDGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKL 356

Query: 254 DEFGEQLSKVISLICVAVWLINIGHF---NDPVHGGSWFRGA--------IYYFKIAVAL 302
                Q+ K   L+      I I +F   N  ++   W            + +F I + +
Sbjct: 357 TRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKFFIIGITV 416

Query: 303 AVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMS 362
            V A+PEGLP  +T  LA   ++M K N +VR L + ET+G  + ICSDKTGTLT N+M+
Sbjct: 417 LVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMT 476

Query: 363 VCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCND 422
           V + +I                 G  +  +   + +     P   D +V   +I +    
Sbjct: 477 VVQAYI-----------------GGIHYRQ---IPSPDVFLPKVLDLIVNGISINSAYTS 516

Query: 423 SSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQLMKKE 482
             L   +  G+  +VG  TE AL   V       TD++   +  R    N V  + + K 
Sbjct: 517 KILPPEKEGGLPRQVGNKTECALLGFV-------TDLKQDYQAVR----NEVPEEKLYKV 565

Query: 483 FTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYV--RVGTTRVPLTGP 540
           +T  F+  RKSMS             G +M+ KGA E ++ +CN +  R G   VP    
Sbjct: 566 YT--FNSVRKSMSTVIRNPNG-----GFRMYSKGASEIILRKCNRILDRKGEA-VPFKNK 617

Query: 541 VKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGVVGML 600
            ++ ++  + E     D LR + +A RD      E   D+    L   T+LT + VVG+ 
Sbjct: 618 DRDDMVRTVIE-PMACDGLRTICIAYRDFDDT--EPSWDNENEIL---TELTCIAVVGIE 671

Query: 601 DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGREFDD 660
           DP R EV  +I  C+ AGI V M+TGDN  TA AI  + GI    ++       G+EF+ 
Sbjct: 672 DPVRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFL--CLEGKEFNR 729

Query: 661 LPLAEQREACRRAC--------CFARVEPSHKSKIVEYL-----QSYDEITAMTGDGVND 707
           L   E+ E  +             AR  P+ K  +V+ +       + ++ A+TGDG ND
Sbjct: 730 LIRNEKGEVEQEKLDKIWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTND 789

Query: 708 APALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLIS 766
            PALKKA++G AMG +GT VAK AS+++L DDNF++IV AV  GR +Y+++ +F+++ ++
Sbjct: 790 GPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLT 849

Query: 767 SNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKE 826
            NV  V+  F  A +     L  VQ+LWVNL+ D   + AL   PP   ++ R P    +
Sbjct: 850 VNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNK 909

Query: 827 PLIS 830
           PLIS
Sbjct: 910 PLIS 913


>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
           sapiens]
          Length = 1176

 Score =  293 bits (749), Expect = 7e-79
 Identities = 263/908 (28%), Positives = 408/908 (44%), Gaps = 160/908 (17%)

Query: 26  PDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWFE--EGEE 83
           P  ++R    +G N +P ++ KT  +LV E  +D+ + IL +AA +S  L++++  EG+ 
Sbjct: 75  PADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIVSLGLSFYQPPEGDN 134

Query: 84  TI--------------TAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKV 129
            +              T ++E   ILL ++   +V  + + + E     L+    +  K 
Sbjct: 135 ALCGEVSVGEEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKF 194

Query: 130 YRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESVSVIK 189
                  V +I   DI  GDI +V  GD +PAD   + I+   L++D+S LTGES  V K
Sbjct: 195 TVIRGGQVIQIPVADITVGDIAQVKYGDLLPADG--ILIQGNDLKIDESSLTGESDHVKK 252

Query: 190 HTEPVPDPRAVNQDKKNMLFSGTNIAAGK------ALGIVATTGV--------------- 228
                      + DK  +L SGT++  G       A+G+ + TG+               
Sbjct: 253 -----------SLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKK 301

Query: 229 ---------GTEIGKIRDQMAATEQD-------------------------------KTP 248
                      + G I ++  A  QD                               K+ 
Sbjct: 302 DEKKKEKKNKKQDGAIENRNKAKAQDGAAMEMQPLKSEEGGDGDEKDKKKANLPKKEKSV 361

Query: 249 LQQKLDEFGEQLSKVISLICVAVWLINIGHFNDP---VHGGSWFRGA--------IYYFK 297
           LQ KL +   Q+ K   L+     +I + +F      V    W            + +F 
Sbjct: 362 LQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFI 421

Query: 298 IAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLT 357
           I V + V A+PEGLP  +T  LA   ++M K N +VR L + ET+G  + ICSDKTGTLT
Sbjct: 422 IGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLT 481

Query: 358 TNQMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATIC 417
            N+M+V + +I +K    +              PE E +       P     LV   ++ 
Sbjct: 482 MNRMTVVQAYINEKHYKKV--------------PEPEAIP------PNILSYLVTGISVN 521

Query: 418 ALCNDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQ 477
                  L   +  G+   VG  TE AL  L+  +     DVR           N +  +
Sbjct: 522 CAYTSKILPPEKEGGLPRHVGNKTECALLGLLLDLKRDYQDVR-----------NEIPEE 570

Query: 478 LMKKEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPL 537
            + K +T  F+  RKSMS     +  S      ++F KGA E ++ +C  +        +
Sbjct: 571 ALYKVYT--FNSVRKSMSTVLKNSDGSY-----RIFSKGASEIILKKCFKILSANGEAKV 623

Query: 538 TGPV-KEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFLEYETDLTFVGV 596
             P  ++ I+  + E     + LR + LA RD P    E   D+    +   T LT + V
Sbjct: 624 FRPRDRDDIVKTVIE-PMASEGLRTICLAFRDFPAGEPEPEWDNENDIV---TGLTCIAV 679

Query: 597 VGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADRAYTGR 656
           VG+ DP R EV  +I+ C+ AGI V M+TGDN  TA AI  + GI    E+       G+
Sbjct: 680 VGIEDPVRPEVPDAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFL--CLEGK 737

Query: 657 EFDDLPLAEQREACRRAC--------CFARVEPSHKSKIVEYL-----QSYDEITAMTGD 703
           +F+     E+ E  +             AR  P+ K  +V+ +         ++ A+TGD
Sbjct: 738 DFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAVTGD 797

Query: 704 GVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIR 762
           G ND PALKKA++G AMG +GT VAK AS+++L DDNF++IV AV  GR +Y+++ +F++
Sbjct: 798 GTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQ 857

Query: 763 YLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPR 822
           + ++ NV  V+  F  A +     L  VQ+LWVNL+ D L + AL   PP   ++ R P 
Sbjct: 858 FQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPY 917

Query: 823 SPKEPLIS 830
              +PLIS
Sbjct: 918 GRNKPLIS 925


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,087,087
Number of Sequences: 37866
Number of extensions: 1588586
Number of successful extensions: 3666
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 3344
Number of HSP's gapped (non-prelim): 162
length of query: 994
length of database: 18,247,518
effective HSP length: 112
effective length of query: 882
effective length of database: 14,006,526
effective search space: 12353755932
effective search space used: 12353755932
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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