Guide to the Human Genome
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Search of human proteins with 239749281

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239749281 PREDICTED: hypothetical protein XP_002346979 [Homo
sapiens]
         (262 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239754746 PREDICTED: hypothetical protein [Homo sapiens]           545   e-155
gi|239749281 PREDICTED: hypothetical protein XP_002346979 [Homo ...   545   e-155
gi|239509062 PREDICTED: hypothetical protein [Homo sapiens]           539   e-153
gi|5730045 solute carrier family 16, member 2 [Homo sapiens]           47   2e-05
gi|187937179 apoptosis-associated tyrosine kinase [Homo sapiens]       47   2e-05
gi|150170670 piccolo isoform 2 [Homo sapiens]                          44   1e-04
gi|150378539 piccolo isoform 1 [Homo sapiens]                          44   1e-04
gi|104876423 heparan sulfate D-glucosaminyl 3-O-sulfotransferase...    43   2e-04
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         43   2e-04
gi|27734799 REST corepressor 2 [Homo sapiens]                          43   3e-04
gi|118498345 AT-binding transcription factor 1 [Homo sapiens]          42   4e-04
gi|50428940 mediator complex subunit 25 [Homo sapiens]                 42   4e-04
gi|9945318 MAX binding protein [Homo sapiens]                          42   5e-04
gi|153792074 proline rich 12 [Homo sapiens]                            42   5e-04
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       42   7e-04
gi|208022661 hypothetical protein LOC57701 [Homo sapiens]              42   7e-04
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s...    42   7e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    41   0.001
gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens]           41   0.001
gi|226437579 NAC alpha domain containing [Homo sapiens]                40   0.002
gi|239754540 PREDICTED: NAC alpha domain containing [Homo sapiens]     40   0.002
gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens]     40   0.002
gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens]     40   0.002
gi|239508792 PREDICTED: NAC alpha domain containing [Homo sapiens]     40   0.002
gi|209862845 nuclear factor of activated T-cells, cytoplasmic, c...    40   0.002
gi|12751477 forkhead box L2 [Homo sapiens]                             40   0.003
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac...    40   0.003
gi|239757987 PREDICTED: hypothetical protein [Homo sapiens]            40   0.003
gi|239755710 PREDICTED: hypothetical protein [Homo sapiens]            40   0.003
gi|21389357 MAPK-interacting and spindle-stabilizing protein [Ho...    40   0.003

>gi|239754746 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 262

 Score =  545 bits (1403), Expect = e-155
 Identities = 262/262 (100%), Positives = 262/262 (100%)

Query: 1   MFLAHSPETRHRNWPCDAPGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGP 60
           MFLAHSPETRHRNWPCDAPGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGP
Sbjct: 1   MFLAHSPETRHRNWPCDAPGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGP 60

Query: 61  GQKPVLPALLSQTQLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIP 120
           GQKPVLPALLSQTQLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIP
Sbjct: 61  GQKPVLPALLSQTQLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIP 120

Query: 121 PSRSSPEPQPPPYPLVSPNLLQASPQAPLTCSTPGLGADDLGDGFGPILGPLVILREPVE 180
           PSRSSPEPQPPPYPLVSPNLLQASPQAPLTCSTPGLGADDLGDGFGPILGPLVILREPVE
Sbjct: 121 PSRSSPEPQPPPYPLVSPNLLQASPQAPLTCSTPGLGADDLGDGFGPILGPLVILREPVE 180

Query: 181 LDLTAEVVAGVLPEGGRDPQAAAQAVSGVIEGGLLLEGLRVRADPTVHLLPIHPPAQLHV 240
           LDLTAEVVAGVLPEGGRDPQAAAQAVSGVIEGGLLLEGLRVRADPTVHLLPIHPPAQLHV
Sbjct: 181 LDLTAEVVAGVLPEGGRDPQAAAQAVSGVIEGGLLLEGLRVRADPTVHLLPIHPPAQLHV 240

Query: 241 VREEACGQAHQCGLLGVGDLCF 262
           VREEACGQAHQCGLLGVGDLCF
Sbjct: 241 VREEACGQAHQCGLLGVGDLCF 262


>gi|239749281 PREDICTED: hypothetical protein XP_002346979 [Homo
           sapiens]
          Length = 262

 Score =  545 bits (1403), Expect = e-155
 Identities = 262/262 (100%), Positives = 262/262 (100%)

Query: 1   MFLAHSPETRHRNWPCDAPGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGP 60
           MFLAHSPETRHRNWPCDAPGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGP
Sbjct: 1   MFLAHSPETRHRNWPCDAPGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGP 60

Query: 61  GQKPVLPALLSQTQLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIP 120
           GQKPVLPALLSQTQLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIP
Sbjct: 61  GQKPVLPALLSQTQLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIP 120

Query: 121 PSRSSPEPQPPPYPLVSPNLLQASPQAPLTCSTPGLGADDLGDGFGPILGPLVILREPVE 180
           PSRSSPEPQPPPYPLVSPNLLQASPQAPLTCSTPGLGADDLGDGFGPILGPLVILREPVE
Sbjct: 121 PSRSSPEPQPPPYPLVSPNLLQASPQAPLTCSTPGLGADDLGDGFGPILGPLVILREPVE 180

Query: 181 LDLTAEVVAGVLPEGGRDPQAAAQAVSGVIEGGLLLEGLRVRADPTVHLLPIHPPAQLHV 240
           LDLTAEVVAGVLPEGGRDPQAAAQAVSGVIEGGLLLEGLRVRADPTVHLLPIHPPAQLHV
Sbjct: 181 LDLTAEVVAGVLPEGGRDPQAAAQAVSGVIEGGLLLEGLRVRADPTVHLLPIHPPAQLHV 240

Query: 241 VREEACGQAHQCGLLGVGDLCF 262
           VREEACGQAHQCGLLGVGDLCF
Sbjct: 241 VREEACGQAHQCGLLGVGDLCF 262


>gi|239509062 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 262

 Score =  539 bits (1388), Expect = e-153
 Identities = 260/262 (99%), Positives = 260/262 (99%)

Query: 1   MFLAHSPETRHRNWPCDAPGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGP 60
           MFLAHSPETRHRNWPCDAPGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGP
Sbjct: 1   MFLAHSPETRHRNWPCDAPGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGP 60

Query: 61  GQKPVLPALLSQTQLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIP 120
           GQKPVLPALLSQTQLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIP
Sbjct: 61  GQKPVLPALLSQTQLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIP 120

Query: 121 PSRSSPEPQPPPYPLVSPNLLQASPQAPLTCSTPGLGADDLGDGFGPILGPLVILREPVE 180
           PSRSSPEPQPPPYPLVSPNLLQASPQAPLTCSTPGLGADDLGDGFGPILGPLVILREPVE
Sbjct: 121 PSRSSPEPQPPPYPLVSPNLLQASPQAPLTCSTPGLGADDLGDGFGPILGPLVILREPVE 180

Query: 181 LDLTAEVVAGVLPEGGRDPQAAAQAVSGVIEGGLLLEGLRVRADPTVHLLPIHPPAQLHV 240
           LDLTAEVVAGVLPEGGRDPQAAAQAVSGVIEGGLLLEGLRV ADPTVHLLPIHPPAQLHV
Sbjct: 181 LDLTAEVVAGVLPEGGRDPQAAAQAVSGVIEGGLLLEGLRVCADPTVHLLPIHPPAQLHV 240

Query: 241 VREEACGQAHQCGLLGVGDLCF 262
           V EEACGQAHQCGLLGVGDLCF
Sbjct: 241 VGEEACGQAHQCGLLGVGDLCF 262


>gi|5730045 solute carrier family 16, member 2 [Homo sapiens]
          Length = 613

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 38/143 (26%), Positives = 51/143 (35%), Gaps = 9/143 (6%)

Query: 27  PSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQK--PVLPALLSQTQLGSFPPLRAP 84
           P  G S    +    S+ C  +N     S   GP     P   AL SQ    +  P +  
Sbjct: 33  PGGGGSGSGSSSPPSSSSCSSRNKYQPQSGSSGPSSHSPPAAMALQSQASEEAKGPWQEA 92

Query: 85  SLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQPPPYPLVSPNLLQAS 144
              Q    G   P+++     +P        P+P+PP    PEPQP P P   P L   S
Sbjct: 93  DQEQQEPVGSPEPESEPEPEPEPE-------PVPVPPPEPQPEPQPLPDPAPLPELEFES 145

Query: 145 PQAPLTCSTPGLGADDLGDGFGP 167
            +      TP +       GF P
Sbjct: 146 ERVHEPEPTPTVETRGTARGFQP 168


>gi|187937179 apoptosis-associated tyrosine kinase [Homo sapiens]
          Length = 1374

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 50/193 (25%), Positives = 67/193 (34%), Gaps = 25/193 (12%)

Query: 6   SPETRHRNWPCDAPGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQKPV 65
           SP+   R  P   PG PG PL       G  A  A   GC                  P 
Sbjct: 710 SPKQTPRASP--EPGYPGEPL------LGLQAASAQEPGCC-----------------PG 744

Query: 66  LPALLSQTQLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSS 125
           LP L S   L   P L  PS ++    G   P A+ +L+ +     G  LPLP  PS S 
Sbjct: 745 LPHLCSAQGLAPAPCLVTPSWTETASSGGDHPQAEPKLATEAEGTTGPRLPLPSVPSPSQ 804

Query: 126 PEPQPPPYPLVSPNLLQASPQAPLTCSTPGLGADDLGDGFGPILGPLVILREPVELDLTA 185
                P     +P+   A P +P   +   + A  L            +     E + TA
Sbjct: 805 EGAPLPSEEASAPDAPDALPDSPTPATGGEVSAIKLASALNGSSSSPEVEAPSSEDEDTA 864

Query: 186 EVVAGVLPEGGRD 198
           E  +G+  +   D
Sbjct: 865 EATSGIFTDTSSD 877



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 41/124 (33%), Positives = 56/124 (45%), Gaps = 14/124 (11%)

Query: 47   GQNTAYLCSQPG------GPGQKPVLPALLSQTQLGSFPPLRAPSLSQHPEPGVLRPDAQ 100
            GQ +  +C +PG      G G   VLP LL Q +  S  P   PS    PEP   +  A+
Sbjct: 1031 GQPSEQVCLRPGVSGEAQGSGPGEVLPPLL-QLEGSSPEPSTCPS-GLVPEPPEPQGPAK 1088

Query: 101  QRLSAQP-LSEWGSCLPLPIPPSRSSPEPQPPPYPLVSPNLLQ-----ASPQAPLTCSTP 154
             R    P  S++    P+P+    +S E Q PP  L  P   +      +P+APL  + P
Sbjct: 1089 VRPGPSPSCSQFFLLTPVPLRSEGNSSEFQGPPGLLSGPAPQKRMGGPGTPRAPLRLALP 1148

Query: 155  GLGA 158
            GL A
Sbjct: 1149 GLPA 1152



 Score = 30.8 bits (68), Expect = 1.3
 Identities = 49/151 (32%), Positives = 64/151 (42%), Gaps = 21/151 (13%)

Query: 19  PGVPGR-PLPSSG----ASAGAP-AYRALSAGCLGQNTAYLCSQPGGPGQKPVLPALLSQ 72
           P  P R P PS+G    A  GA  A   ++A C       L + P G    P LP L  +
Sbjct: 603 PLCPSRSPSPSAGPLSLAEGGAEDADWGVAAFCPAFFEDPLGTSPLGSSGAPPLP-LTGE 661

Query: 73  TQLGSFPPLRAP-------SLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSS 125
            +L      RA        ++S +   G   P++   +SA   +E   C P P    R+S
Sbjct: 662 DELEEVGARRAAQRGHWRSNVSANNNSGSRCPESWDPVSAGGHAE--GC-PSPKQTPRAS 718

Query: 126 PEPQPPPYPLVSPNLLQASPQAPLTCSTPGL 156
           PEP  P  PL+   L  AS Q P  C  PGL
Sbjct: 719 PEPGYPGEPLL--GLQAASAQEPGCC--PGL 745


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 39/117 (33%), Positives = 48/117 (41%), Gaps = 6/117 (5%)

Query: 15  PCDAPGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQKPVLPALLSQTQ 74
           P   PG P +P P     A  P  +  SA    Q        P  PG     P     T+
Sbjct: 470 PSQLPG-PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK 528

Query: 75  LGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQPP 131
             S  P  A   +Q P P   +P AQQ  S +P+S+ GS  PL  PP+ S    QPP
Sbjct: 529 PPSQQPGSAKPSAQQPSPA--KPSAQQ--STKPVSQTGSGKPLQ-PPTVSPSAKQPP 580



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 42/144 (29%), Positives = 54/144 (37%), Gaps = 10/144 (6%)

Query: 15  PCDAPGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQKPVL---PALLS 71
           P   PG    P    G          L +            Q  GPG+ P     P   S
Sbjct: 401 PAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTS 460

Query: 72  QTQLG-SFPPLRAPSLSQHP--EPGVLRPDAQQRLSAQPLSEW-GSCLPLPIPPSRSSPE 127
             Q G + PP + P  ++ P  +PG  +P  QQ  SA+P S+  GS  P P  P  + P 
Sbjct: 461 AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS 520

Query: 128 PQPP---PYPLVSPNLLQASPQAP 148
           PQ P     P   P   + S Q P
Sbjct: 521 PQQPGSTKPPSQQPGSAKPSAQQP 544



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 46/169 (27%), Positives = 64/169 (37%), Gaps = 24/169 (14%)

Query: 4   AHSPETRHRNWPCDAPGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQK 63
           A  P+T+  +        P  P PS       P  +        Q   +  SQPG P + 
Sbjct: 278 ASRPQTKQADIVRGESVKPSLPSPSK-----PPIQQPTPGKPPAQQPGHEKSQPG-PAKP 331

Query: 64  PVLPALLSQT---QLGSF-PPLRAPSLSQHPEP--GVLRPDAQQRLSAQPLSEWGSCLPL 117
           P  P+ L++    Q G+  PP++ P  ++ P    G  +P AQQ  S +P SE      L
Sbjct: 332 PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKAL 391

Query: 118 PIPPSRSSPEPQPP------------PYPLVSPNLLQASPQAPLTCSTP 154
             PP       Q P            P PL     LQ+  +AP    TP
Sbjct: 392 AQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440



 Score = 35.4 bits (80), Expect = 0.051
 Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 9/87 (10%)

Query: 80   PLRAPSLSQHP-EPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQPPPYPLVSP 138
            P  +PS+S  P +P      +   +SAQP        P P PP    P P PPP PL  P
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPP------PPPPPPPPPPPPPPPPPPPLPPP 2430

Query: 139  NLLQAS--PQAPLTCSTPGLGADDLGD 163
               + +  P+  LT ++P   A  L D
Sbjct: 2431 TSPKPTILPKKKLTVASPVTTATPLFD 2457



 Score = 32.7 bits (73), Expect = 0.33
 Identities = 32/117 (27%), Positives = 48/117 (41%), Gaps = 27/117 (23%)

Query: 59  GPGQKPVLPALLSQTQLGSFPPLRAPSLSQHP---------EPGVLRPDAQQRLSAQPLS 109
           G   KP LP+        S PP++ P+  + P         +PG  +P AQ     +PL+
Sbjct: 291 GESVKPSLPS-------PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLA 343

Query: 110 EWGSCLPLPI-PPSRSSPEPQP-----PPYPLV---SPNLLQASPQAPLTCSTPGLG 157
           +    +  P+ PP  + P  QP     PP        P+  Q  P+A      PG+G
Sbjct: 344 QQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKA--LAQPPGVG 398



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 31/128 (24%), Positives = 41/128 (32%), Gaps = 12/128 (9%)

Query: 22  PGRPLPSSGASAGAPAYR-ALSAGCLGQNTAYLCSQPGGPGQKPVLPALLSQTQLGSFPP 80
           P +P+P        P  +         Q    + SQP G G+    P    QT     P 
Sbjct: 215 PPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPL 274

Query: 81  LRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQPPPYPLVSPNL 140
            R  S  Q  +  ++R +     S +P       LP P  P    P P  PP        
Sbjct: 275 QRDASRPQTKQADIVRGE-----SVKP------SLPSPSKPPIQQPTPGKPPAQQPGHEK 323

Query: 141 LQASPQAP 148
            Q  P  P
Sbjct: 324 SQPGPAKP 331



 Score = 29.6 bits (65), Expect = 2.8
 Identities = 38/133 (28%), Positives = 55/133 (41%), Gaps = 19/133 (14%)

Query: 30   GASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQKPVLPALLSQTQ-----LGSFPPLRAP 84
            GAS  + A   +S    GQ   +  S PG P ++   P+    +Q      G  PP  A 
Sbjct: 935  GASIFSQASNLISTA--GQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAK 992

Query: 85   SL-----SQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRS-SPEPQPPPYPLVSP 138
            S+     ++ P    L P A+Q  + +         P PI  S+S + EPQ      V P
Sbjct: 993  SIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKK--PPPIKDSKSLTAEPQKA----VLP 1046

Query: 139  NLLQASPQAPLTC 151
              L+ SP+   TC
Sbjct: 1047 TKLEKSPKPESTC 1059


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 39/117 (33%), Positives = 48/117 (41%), Gaps = 6/117 (5%)

Query: 15  PCDAPGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQKPVLPALLSQTQ 74
           P   PG P +P P     A  P  +  SA    Q        P  PG     P     T+
Sbjct: 470 PSQLPG-PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK 528

Query: 75  LGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQPP 131
             S  P  A   +Q P P   +P AQQ  S +P+S+ GS  PL  PP+ S    QPP
Sbjct: 529 PPSQQPGSAKPSAQQPSPA--KPSAQQ--STKPVSQTGSGKPLQ-PPTVSPSAKQPP 580



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 42/144 (29%), Positives = 54/144 (37%), Gaps = 10/144 (6%)

Query: 15  PCDAPGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQKPVL---PALLS 71
           P   PG    P    G          L +            Q  GPG+ P     P   S
Sbjct: 401 PAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTS 460

Query: 72  QTQLG-SFPPLRAPSLSQHP--EPGVLRPDAQQRLSAQPLSEW-GSCLPLPIPPSRSSPE 127
             Q G + PP + P  ++ P  +PG  +P  QQ  SA+P S+  GS  P P  P  + P 
Sbjct: 461 AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS 520

Query: 128 PQPP---PYPLVSPNLLQASPQAP 148
           PQ P     P   P   + S Q P
Sbjct: 521 PQQPGSTKPPSQQPGSAKPSAQQP 544



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 46/169 (27%), Positives = 64/169 (37%), Gaps = 24/169 (14%)

Query: 4   AHSPETRHRNWPCDAPGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQK 63
           A  P+T+  +        P  P PS       P  +        Q   +  SQPG P + 
Sbjct: 278 ASRPQTKQADIVRGESVKPSLPSPSK-----PPIQQPTPGKPPAQQPGHEKSQPG-PAKP 331

Query: 64  PVLPALLSQT---QLGSF-PPLRAPSLSQHPEP--GVLRPDAQQRLSAQPLSEWGSCLPL 117
           P  P+ L++    Q G+  PP++ P  ++ P    G  +P AQQ  S +P SE      L
Sbjct: 332 PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKAL 391

Query: 118 PIPPSRSSPEPQPP------------PYPLVSPNLLQASPQAPLTCSTP 154
             PP       Q P            P PL     LQ+  +AP    TP
Sbjct: 392 AQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440



 Score = 35.4 bits (80), Expect = 0.051
 Identities = 29/87 (33%), Positives = 39/87 (44%), Gaps = 9/87 (10%)

Query: 80   PLRAPSLSQHP-EPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQPPPYPLVSP 138
            P  +PS+S  P +P      +   +SAQP        P P PP    P P PPP PL  P
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPP------PPPPPPPPPPPPPPPPPPPLPPP 2430

Query: 139  NLLQAS--PQAPLTCSTPGLGADDLGD 163
               + +  P+  LT ++P   A  L D
Sbjct: 2431 TSPKPTILPKKKLTVASPVTTATPLFD 2457



 Score = 32.7 bits (73), Expect = 0.33
 Identities = 32/117 (27%), Positives = 48/117 (41%), Gaps = 27/117 (23%)

Query: 59  GPGQKPVLPALLSQTQLGSFPPLRAPSLSQHP---------EPGVLRPDAQQRLSAQPLS 109
           G   KP LP+        S PP++ P+  + P         +PG  +P AQ     +PL+
Sbjct: 291 GESVKPSLPS-------PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLA 343

Query: 110 EWGSCLPLPI-PPSRSSPEPQP-----PPYPLV---SPNLLQASPQAPLTCSTPGLG 157
           +    +  P+ PP  + P  QP     PP        P+  Q  P+A      PG+G
Sbjct: 344 QQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKA--LAQPPGVG 398



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 31/128 (24%), Positives = 41/128 (32%), Gaps = 12/128 (9%)

Query: 22  PGRPLPSSGASAGAPAYR-ALSAGCLGQNTAYLCSQPGGPGQKPVLPALLSQTQLGSFPP 80
           P +P+P        P  +         Q    + SQP G G+    P    QT     P 
Sbjct: 215 PPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPL 274

Query: 81  LRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQPPPYPLVSPNL 140
            R  S  Q  +  ++R +     S +P       LP P  P    P P  PP        
Sbjct: 275 QRDASRPQTKQADIVRGE-----SVKP------SLPSPSKPPIQQPTPGKPPAQQPGHEK 323

Query: 141 LQASPQAP 148
            Q  P  P
Sbjct: 324 SQPGPAKP 331



 Score = 29.6 bits (65), Expect = 2.8
 Identities = 38/133 (28%), Positives = 55/133 (41%), Gaps = 19/133 (14%)

Query: 30   GASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQKPVLPALLSQTQ-----LGSFPPLRAP 84
            GAS  + A   +S    GQ   +  S PG P ++   P+    +Q      G  PP  A 
Sbjct: 935  GASIFSQASNLISTA--GQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAK 992

Query: 85   SL-----SQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRS-SPEPQPPPYPLVSP 138
            S+     ++ P    L P A+Q  + +         P PI  S+S + EPQ      V P
Sbjct: 993  SIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKK--PPPIKDSKSLTAEPQKA----VLP 1046

Query: 139  NLLQASPQAPLTC 151
              L+ SP+   TC
Sbjct: 1047 TKLEKSPKPESTC 1059


>gi|104876423 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4
           [Homo sapiens]
          Length = 456

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 66/245 (26%), Positives = 80/245 (32%), Gaps = 60/245 (24%)

Query: 14  WPCDAPGVPGRPL----PSSGASAGAPAYRALSAGC-LGQNTAYLC-SQPGGPGQKPVLP 67
           WP   P  P  P     P  GASA  P  R L   C L  +  YLC S  GG G     P
Sbjct: 4   WPAPPPPPPPPPPLAAPPPPGASAKGPPARKLLFMCTLSLSVTYLCYSLLGGSGSLQ-FP 62

Query: 68  ALLSQTQLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPE 127
             L ++          P  +  P P    P               S LP P+     S  
Sbjct: 63  LALQES----------PGAAAEPPPSPPPP---------------SLLPTPVRLGAPSQP 97

Query: 128 PQPPPYPLVSPNLLQASPQAPLTCSTPGLGADDLGDG-----FGPILGPLVIL------- 175
           P PPP    S       P+ P    T G G    G G         L P  ++       
Sbjct: 98  PAPPPLDNASHGEPPEPPEQPAAPGTDGWGLPSGGGGAQDAWLRTPLAPSEMITAQSALP 157

Query: 176 -REPVELDLTAEVVAGVLPEGGRDPQAAAQA-------------VSGVIEGG--LLLEGL 219
            RE  E   T E +AG     G   +  A +             + GV +GG   LLE +
Sbjct: 158 EREAQESSTTDEDLAGRRAANGSSERGGAVSTPDYGEKKLPQALIIGVKKGGTRALLEAI 217

Query: 220 RVRAD 224
           RV  D
Sbjct: 218 RVHPD 222


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 50/161 (31%), Positives = 62/161 (38%), Gaps = 25/161 (15%)

Query: 18   APGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQKPVL-------PALL 70
            AP VP  P P S A +GA    + SA  LG  TA   S    PG   +L       P L 
Sbjct: 1481 APVVPAAPGPPSLAPSGASP--SASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLN 1538

Query: 71   SQTQLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRS------ 124
            S       P L   S    P P    P   Q     P S     L  P+ P  +      
Sbjct: 1539 STVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAIL 1598

Query: 125  SPEPQPP--PYPLVSPN----LLQASPQAPL----TCSTPG 155
            +P P PP  P P+++P+     + AS Q P+      STPG
Sbjct: 1599 APSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPG 1639



 Score = 37.0 bits (84), Expect = 0.017
 Identities = 55/222 (24%), Positives = 74/222 (33%), Gaps = 27/222 (12%)

Query: 6    SPETRHRNWPCDAPGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQKPV 65
            +P +     P   P     PLPS  ++       AL+    G + +   S   G  Q P 
Sbjct: 1656 APSSTQTMLPAPVPS----PLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPF 1711

Query: 66   LPALLSQTQLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLP-----IP 120
                LS T   S  P  A +LS  P P +          A PL+      P P     + 
Sbjct: 1712 PTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLA 1771

Query: 121  PSRSSPE-----------PQPPPYPLVSPNLLQASPQAPLTCSTPGLGADDL---GDGFG 166
            P+ SS               P P P + P   Q    AP +  +P   A  L     G  
Sbjct: 1772 PASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAA 1831

Query: 167  PILGPLVILREPVELDLTAEVVAGVLPEGGRDPQAAAQAVSG 208
            P L   ++ R PV  D   E     L  G   P + A +  G
Sbjct: 1832 P-LPVTMVSRLPVSKD---EPDTLTLRSGPPSPPSTATSFGG 1869



 Score = 35.0 bits (79), Expect = 0.066
 Identities = 63/221 (28%), Positives = 78/221 (35%), Gaps = 29/221 (13%)

Query: 35   APAYRALSAGCLGQNTAYLCSQPG-GPGQKPVLPALLSQTQLGSFPPLRAPSL----SQH 89
            APA R  S+G      A L  +P   PG+ P  P L +       P L  P L    S  
Sbjct: 1328 APAPRPPSSGL----PAVLNPRPTLTPGRLPT-PTLGTARAPMPTPTLVRPLLKLVHSPS 1382

Query: 90   PEPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQPPPYPLVSPNLLQASPQAPL 149
            PE     P A     + PL      +P  +P   SSP P P   PL SP  + ++   PL
Sbjct: 1383 PEVSASAPGAAPLTISSPLH-----VPSSLPGPASSPMPIPNSSPLASP--VSSTVSVPL 1435

Query: 150  TCSTP-----GLGADDLGDGFGPILGPLVILRE-PVELDLTAEVVAGVLPEGGRDPQAAA 203
            + S P      L A        PI  PL +    P  L      +A V+P     P  A 
Sbjct: 1436 SSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAP 1495

Query: 204  QAVSGVIEGGLLLEGLRVRADPTVHLLPIHP----PAQLHV 240
               S       L  GL      +    P HP    P   HV
Sbjct: 1496 SGASP--SASALTLGLATAPSLSSSQTPGHPLLLAPTSSHV 1534



 Score = 34.7 bits (78), Expect = 0.087
 Identities = 41/141 (29%), Positives = 51/141 (36%), Gaps = 11/141 (7%)

Query: 15   PCDAPGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQKPVLPALLSQTQ 74
            P  AP       P+S AS       A  A      TA L   P      P+ P  +    
Sbjct: 1563 PNPAPAQASLLAPASSASQALATPLAPMAA---PQTAILAPSPA----PPLAPLPVLAPS 1615

Query: 75   LGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQPPPYP 134
             G+ P L +   SQ P P V+ P +    S    S   +  P+  P S  +  P P P P
Sbjct: 1616 PGAAPVLAS---SQTPVP-VMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSP 1671

Query: 135  LVSPNLLQASPQAPLTCSTPG 155
            L SP   Q    AP    T G
Sbjct: 1672 LPSPASTQTLALAPALAPTLG 1692



 Score = 28.9 bits (63), Expect = 4.8
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 14/100 (14%)

Query: 59   GPGQKPVLPALLSQTQLGSFPPLRAPSLSQHPEPGVL-RPDAQQRLSAQPLSEWGSCLPL 117
            G    PV+ A   QT+  + PP  +P+  + P P    RP      +A P         +
Sbjct: 2408 GANHTPVISA--HQTRSTTTPPRCSPARERVPRPAPRPRPTPASAPAAIPAL-------V 2458

Query: 118  PIPPSRSSPEPQPPPYPLVSPNLLQASP---QAPLTCSTP 154
            P+P S   P   P P  ++  ++L + P   Q P  CS+P
Sbjct: 2459 PVPVSAPVPISAPNPITILPVHILPSPPPPSQIP-PCSSP 2497



 Score = 28.5 bits (62), Expect = 6.2
 Identities = 42/142 (29%), Positives = 53/142 (37%), Gaps = 23/142 (16%)

Query: 21   VPGRPLPSSGASAG---APAYRALSAGCLGQNTAYLCSQPGGPGQKPVLPALLS--QTQL 75
            VP RP P    SA     P  + L A  +   +A     P  P  +P  P LL   Q   
Sbjct: 1022 VPVRPPPGPELSAQPTPGPVPQVLPASLMV--SASPAGPPLIPASRPPGPVLLPPLQPNS 1079

Query: 76   GSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQPPPYPL 135
            GS P +    L      GVL        +++P +   S  P P  P R SP P P    L
Sbjct: 1080 GSLPQVLPSPL------GVLSG------TSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSL 1127

Query: 136  VSPNLLQAS----PQAPLTCST 153
            + P  +       P A  T ST
Sbjct: 1128 LKPLTVPPGYTFPPAAATTTST 1149


>gi|27734799 REST corepressor 2 [Homo sapiens]
          Length = 523

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 41/138 (29%), Positives = 50/138 (36%), Gaps = 3/138 (2%)

Query: 12  RNWPCDAPGVPGRPLPSSGASAGAPAYR-ALSAGCLGQNTAYLCSQPGGPGQKPVLPALL 70
           + W  +  G PG P+P   A  GAP    AL      Q T+   S P      P  P   
Sbjct: 384 QEWEAEQDGAPGAPVPMEEARRGAPLPAPALEEDDEVQITSVSTSVPRSVPPAPPPPP-- 441

Query: 71  SQTQLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQP 130
             T L   PPL  P L   P      P  QQ    QP        P  I P+ ++P    
Sbjct: 442 PPTSLSQPPPLLRPPLPTAPTLLRQPPPLQQGRFLQPRLAPNQPPPPLIRPALAAPRHSA 501

Query: 131 PPYPLVSPNLLQASPQAP 148
            P P   P L+ A  + P
Sbjct: 502 RPGPQPPPTLIGAPLEPP 519


>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
          Length = 3703

 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 41/143 (28%), Positives = 57/143 (39%), Gaps = 23/143 (16%)

Query: 25   PLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQKPVLPALLSQTQLGSFPPLRAP 84
            P+PS   SA AP+    ++    Q TA          +   L    S+T+ G   P  A 
Sbjct: 2385 PMPSQAYSAPAPSANNTASSAFLQLTA----------EAEELATFNSKTEAGDEKPKLAE 2434

Query: 85   SLSQHP-----EPGVLRPDAQQR--------LSAQPLSEWGSCLPLPIPPSRSSPEPQPP 131
            + S  P     + G  +P+ QQ+           Q L +  S   LP PP ++ P   P 
Sbjct: 2435 APSAQPNQTQEKQGQPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPL 2494

Query: 132  PYPLVSPNLLQASPQAPLTCSTP 154
            P    SP+ L   P  PL  STP
Sbjct: 2495 PQSSPSPSQLSHLPLKPLHTSTP 2517



 Score = 33.5 bits (75), Expect = 0.19
 Identities = 23/76 (30%), Positives = 31/76 (40%), Gaps = 2/76 (2%)

Query: 120  PPSRSSPEPQPPPYPLVSPNLLQASPQAPLTCSTPGLGADDLGDGFGPILG--PLVILRE 177
            P    +PEP PPP P   P L  A PQ   T + P            P     PL  L  
Sbjct: 2031 PLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSM 2090

Query: 178  PVELDLTAEVVAGVLP 193
            P+EL + + ++   +P
Sbjct: 2091 PMELPIFSPLMMQTMP 2106



 Score = 29.3 bits (64), Expect = 3.6
 Identities = 21/77 (27%), Positives = 29/77 (37%), Gaps = 20/77 (25%)

Query: 116  PLPIPPSRSSPEPQPPPYP------------LVSPNLLQASPQAPLTCSTPGLGADDLGD 163
            P P PP    P P  PP P            + SP +  A P  PLT  +  +       
Sbjct: 2040 PPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLSMPMEL----- 2094

Query: 164  GFGPILGPLVILREPVE 180
               PI  PL++   P++
Sbjct: 2095 ---PIFSPLMMQTMPLQ 2108


>gi|50428940 mediator complex subunit 25 [Homo sapiens]
          Length = 747

 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 44/142 (30%), Positives = 53/142 (37%), Gaps = 9/142 (6%)

Query: 18  APGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQKPVLPALLSQT---Q 74
           A G  G+P P   A     A +       G        +P  PG  P L +LL      Q
Sbjct: 598 ASGATGQPQPQGTAQPPPGAPQGPPGAASGPPPPGPILRPQNPGANPQLRSLLLNPPPPQ 657

Query: 75  LGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQPPPYP 134
            G  PP  +    Q P    L P   Q L    L   G  L  P PP++S P   PP  P
Sbjct: 658 TGVPPPQASLHHLQPPGAPALLPPPHQGLGQPQL---GPPLLHP-PPAQSWPAQLPPRAP 713

Query: 135 LVSPNLLQASPQAPLTCSTPGL 156
           L    LL   P+ P+    PGL
Sbjct: 714 LPGQMLLSGGPRGPV--PQPGL 733



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 48/155 (30%), Positives = 61/155 (39%), Gaps = 24/155 (15%)

Query: 72  QTQLGSFPPLRAP-----SLSQHPEPG-VLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSS 125
           Q Q  + PP  AP     + S  P PG +LRP   Q   A P  +  S L  P PP    
Sbjct: 606 QPQGTAQPPPGAPQGPPGAASGPPPPGPILRP---QNPGANP--QLRSLLLNPPPPQTGV 660

Query: 126 PEPQPPPYPLVSPNLLQASPQAPLTCSTP--GLGADDLGDGFGPILGPLVILREPVELDL 183
           P PQ   + L  P        AP     P  GLG   LG    P+L P      P +L  
Sbjct: 661 PPPQASLHHLQPPG-------APALLPPPHQGLGQPQLGP---PLLHPPPAQSWPAQLPP 710

Query: 184 TAEVVAGVLPEGG-RDPQAAAQAVSGVIEGGLLLE 217
            A +   +L  GG R P         V+E  +L++
Sbjct: 711 RAPLPGQMLLSGGPRGPVPQPGLQPSVMEDDILMD 745



 Score = 28.9 bits (63), Expect = 4.8
 Identities = 30/110 (27%), Positives = 43/110 (39%), Gaps = 16/110 (14%)

Query: 64  PVLPALLSQTQLGSFPPLRAPSLS-QHPEPGVL---RPDAQQRLSA------------QP 107
           P+ PA  S   L + P    P +  Q+  PG L   +  AQ  + A             P
Sbjct: 246 PLPPAAPSGATLSAAPQQPLPPVPPQYQVPGNLSAAQVAAQNAVEAAKNQKAGLGPRFSP 305

Query: 108 LSEWGSCLPLPIPPSRSSPEPQPPPYPLVSPNLLQASPQAPLTCSTPGLG 157
           ++      P   PP   +P PQ PP P  +P    AS  + ++   PG G
Sbjct: 306 ITPLQQAAPGVGPPFSQAPAPQLPPGPPGAPKPPPASQPSLVSTVAPGSG 355


>gi|9945318 MAX binding protein [Homo sapiens]
          Length = 582

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 3/87 (3%)

Query: 71  SQTQLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQP 130
           S  +L    P+  P +   P P  L P A       PL+       +PIP   +SP+P P
Sbjct: 45  SLARLAHTLPVEEPRMEAPPLP--LSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLP 102

Query: 131 PPYPL-VSPNLLQASPQAPLTCSTPGL 156
           PP PL  +   L  +P+ P     PGL
Sbjct: 103 PPPPLPAAAQPLPLAPRQPALVGAPGL 129



 Score = 33.5 bits (75), Expect = 0.19
 Identities = 30/93 (32%), Positives = 37/93 (39%), Gaps = 19/93 (20%)

Query: 64  PVLPALLSQTQLGSFPPLRAPSLSQHPEPGVLRPDAQQRL----SAQPLSEWGSCLPLPI 119
           P  PAL+    L    P   PS  Q P P  L PD++  +    S +PL       PLP 
Sbjct: 118 PRQPALVGAPGLSIKEPAPLPSRPQVPTPAPLLPDSKATIPPNGSPKPLQ------PLPT 171

Query: 120 PPSRSSPEP---------QPPPYPLVSPNLLQA 143
           P    +P P         QPPP  L +  L  A
Sbjct: 172 PVLTIAPHPGVQPQLAPQQPPPPTLGTLKLAPA 204



 Score = 28.5 bits (62), Expect = 6.2
 Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 1/51 (1%)

Query: 100 QQRLSAQPLSEWGSCLPLPIPPSRSSPEPQPPPYPLVSPNLLQASPQAPLT 150
           Q++  A  L+     LP+  P   + P P  PP P  +P    A+P APLT
Sbjct: 38  QEQKKANSLARLAHTLPVEEPRMEAPPLPLSPPAPPPAPPPPLATP-APLT 87


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 43/143 (30%), Positives = 49/143 (34%), Gaps = 34/143 (23%)

Query: 15   PCDAPGVPGRPLPSSGASAGAPAYRAL-SAGCLGQNTAYLCSQPGGPGQKPVL------- 66
            P D     G PL  + A  G P    L SA   G     L  +   P   P         
Sbjct: 1413 PKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPP 1472

Query: 67   -PALLSQTQLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSS 125
             P    Q  L S PPL AP+ S  P P                       PLP PP  + 
Sbjct: 1473 PPPPPPQPALPSPPPLVAPTPSSPPPP-----------------------PLPPPPPPAM 1509

Query: 126  PEPQPPPYPLVSPNLLQASPQAP 148
            P P PPP P  +P  L A P+ P
Sbjct: 1510 PSPPPPPPPAAAP--LAAPPEEP 1530



 Score = 34.7 bits (78), Expect = 0.087
 Identities = 32/105 (30%), Positives = 39/105 (37%), Gaps = 19/105 (18%)

Query: 60   PGQKPVLPALLSQTQLGSF---------PPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSE 110
            PG  P LP L S    G+          PP   P+ +  P+P    P  Q  L + P   
Sbjct: 1431 PGPPP-LPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPP--- 1486

Query: 111  WGSCLPLPIP-PSRSSPEPQPPPYPLVSPNLLQASPQAPLTCSTP 154
                 PL  P PS   P P PPP P   P+     P A    + P
Sbjct: 1487 -----PLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAP 1526



 Score = 32.0 bits (71), Expect = 0.56
 Identities = 34/138 (24%), Positives = 45/138 (32%), Gaps = 41/138 (29%)

Query: 19   PGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPG---GPGQKPVLPALLSQTQL 75
            P   G P   +G   G PAY      C G+ +      PG    P + P LP+ ++   L
Sbjct: 968  PEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPL 1027

Query: 76   GSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQPPPYPL 135
            G                               L + G     P PP    P P PPP P 
Sbjct: 1028 G-------------------------------LIQSGPHQAAPPPP----PPPPPPPAPA 1052

Query: 136  VSPNLLQASPQAPLTCST 153
              P   +    +P+ CST
Sbjct: 1053 SEP---KGGLTSPIFCST 1067



 Score = 30.4 bits (67), Expect = 1.6
 Identities = 46/159 (28%), Positives = 59/159 (37%), Gaps = 26/159 (16%)

Query: 53  LCSQPGGPGQKPVLPALLSQTQLGSFPPLRAPSLSQH-PEPGVLRPDAQQRLSAQPLSEW 111
           L  + GGP    VLP           PP   PS+  H P P          L  +P +  
Sbjct: 781 LLLEAGGPDLPLVLPPP---------PPQLLPSVLSHAPSPSPSASKVGVHL-LEPATRD 830

Query: 112 GSCLPLPIPPSRSSPEPQPPPYPLVSPNLLQA---SPQAPLTCSTPGLGADDLGDGFGPI 168
           G+  P P PP    P P PPP PL     L++    P AP     P    D  G     +
Sbjct: 831 GA--PQPPPP----PPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPG-AMQEL 883

Query: 169 LGPLVILREPVELDLTAEVVAGVLPEGGRDPQAAAQAVS 207
           LG L    EP+      +   G     G+DP  A ++ S
Sbjct: 884 LGAL----EPLP-PAPGDTGVGPPNSEGKDPAGAYRSPS 917



 Score = 28.9 bits (63), Expect = 4.8
 Identities = 23/62 (37%), Positives = 31/62 (50%), Gaps = 7/62 (11%)

Query: 6   SPETRHRNWPCDAPGVPGRPLPSSGASA------GAPAYRALSAGCLGQ-NTAYLCSQPG 58
           SP    R     +PG PG+ L S  ASA      GA +Y A + G  G+ + + L + PG
Sbjct: 570 SPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPG 629

Query: 59  GP 60
           GP
Sbjct: 630 GP 631



 Score = 28.1 bits (61), Expect = 8.1
 Identities = 38/131 (29%), Positives = 51/131 (38%), Gaps = 21/131 (16%)

Query: 29  SGASAGAPAYRALSAGCLGQNTAYLCSQP---------GGPGQKPVLPALLSQTQLGSFP 79
           SGA  G+  + + SA    Q+ A   S+P           P   P    LLS   +    
Sbjct: 133 SGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLK 192

Query: 80  PLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQPPPYPLVSP- 138
           P +AP++     P  L     +RL+   +       P   PP R  P P PPP P   P 
Sbjct: 193 PSQAPTV-----PSSL---GFERLAGGGVLGPAGLGPAQTPPYRPGP-PDPPPPPRHLPT 243

Query: 139 --NLLQASPQA 147
             NLL +S  A
Sbjct: 244 QFNLLASSSAA 254


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 50/186 (26%), Positives = 68/186 (36%), Gaps = 8/186 (4%)

Query: 53  LCSQPGGPGQKPVLPALLSQTQLGSFP-PLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEW 111
           +CS P   G  PVLP  L    LG++  P  AP L     P    P + Q+    P   +
Sbjct: 651 VCSPPVSEG--PVLPQSLPS--LGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSF 706

Query: 112 GSCLPLPIPPSRSSPEPQPPPYPLVSPNLLQASPQAPLTCSTPGLGADDLGDGFGPILGP 171
              LP P  P  + P  QP P     P L Q +P   +    P +    +     P L P
Sbjct: 707 APVLPPPSTPMPTGP-GQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAP 765

Query: 172 LVILREPVELDLTAEVVAGVLPEGGRDPQAAAQAVSGVIEGGLLLEGLRVRAD--PTVHL 229
              +  P +L       A + P     PQ     V   I     ++GL       PT  +
Sbjct: 766 ASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATV 825

Query: 230 LPIHPP 235
            P+ PP
Sbjct: 826 PPVPPP 831



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 50/181 (27%), Positives = 61/181 (33%), Gaps = 26/181 (14%)

Query: 15   PCDAPGVPGRPL-PSSGASAGAPAYRALSA-GCLGQNTAYLCSQPGGPGQKPVLPALLSQ 72
            P + PG P  PL PSS      P   A  A   + +  +   SQ GGPG    L + L  
Sbjct: 1373 PSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELET 1432

Query: 73   TQLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCL-------PLPIPPSRSS 125
            +Q         P    H  P  ++P         P  E  S         PLP P    S
Sbjct: 1433 SQ---------PLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPS 1483

Query: 126  PEPQPPPYPLVSPNLLQASPQAPLTCSTPGLGADDLGDGFGPILGPLVILREPVELDLTA 185
            P    P      P L Q +P  P       L    L     P LGP V  + P  L+   
Sbjct: 1484 PHSGTP-----QPALGQPAPLLPAAVGAVSLATSQLP---SPPLGPTVPPQPPSALESDG 1535

Query: 186  E 186
            E
Sbjct: 1536 E 1536



 Score = 32.3 bits (72), Expect = 0.43
 Identities = 40/136 (29%), Positives = 55/136 (40%), Gaps = 39/136 (28%)

Query: 56  QPGGPGQKPV-------LPALLS-------QTQLGSFPPLRAPSLSQHPEPGVLRPDAQQ 101
           QP  PGQ+P        LP +L+       Q      PP  AP+ SQ   P  L+P    
Sbjct: 723 QPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPA-SQVGAPAQLKPLQMP 781

Query: 102 RLSAQPLSEWGSCLPLPIP---------------------PSRSSPEPQPPPYPLVSPNL 140
           +   QPL++    +P PIP                     P+ + P P PPP    SP +
Sbjct: 782 QAPLQPLAQVPPQMP-PIPVVPPITPLAGIDGLPPALPDLPTATVP-PVPPP-QYFSPAV 838

Query: 141 LQASPQAPLTCSTPGL 156
           +  S  APL  ++P L
Sbjct: 839 ILPSLAAPLPPASPAL 854



 Score = 32.0 bits (71), Expect = 0.56
 Identities = 31/97 (31%), Positives = 41/97 (42%), Gaps = 10/97 (10%)

Query: 60   PGQKPVLPALLSQTQLGSFPPL---RAPSLSQHPEPGVLRPDAQQRLSAQP-LSEWGSCL 115
            PGQ PV PA   Q      PP       ++   P    L P  Q  L  QP L    +  
Sbjct: 907  PGQ-PVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPP--QPTLPPQPVLPPQPTLP 963

Query: 116  PLPIPPSRSSPEPQP--PPYPLVSPN-LLQASPQAPL 149
            P P+ P + +  PQP  PP P++ P  +L   P  P+
Sbjct: 964  PQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPV 1000


>gi|208022661 hypothetical protein LOC57701 [Homo sapiens]
          Length = 1334

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 46/158 (29%), Positives = 61/158 (38%), Gaps = 20/158 (12%)

Query: 15  PCDAPGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQKPVLPALLSQTQ 74
           P  A G+    LP +   + +P    LS   L +N+   C   G  G       LL++  
Sbjct: 450 PSPARGLKFLKLPPTSEKSPSPGGPQLSPQ-LPRNSRIPCRNSGSDGSPS---PLLARRG 505

Query: 75  LGS--FPPLRAPSLSQHPEPGVLRPDAQQRLSAQ--------PLSEWGSCLPLPIPPSRS 124
           LG     P  A  L   P P    PD+ Q    Q        P      C    +  SRS
Sbjct: 506 LGGGELSPEGAQGLPTSPSPCYTTPDSTQLRPPQSALSTTLSPGPVVSPCYENILDLSRS 565

Query: 125 S---PEPQPPPYPLVSPNLLQAS---PQAPLTCSTPGL 156
           +   P P+PPP PL  P   Q +   PQAP    +PG+
Sbjct: 566 TFRGPSPEPPPSPLQVPTYPQLTLEVPQAPEVLRSPGV 603



 Score = 35.0 bits (79), Expect = 0.066
 Identities = 48/176 (27%), Positives = 57/176 (32%), Gaps = 36/176 (20%)

Query: 15  PCDAPGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQ--PGGPGQKPVLPALLSQ 72
           P   P  P  P   S +S   PA       C GQ       Q  PGGPG     P  L  
Sbjct: 122 PLQPPSEP--PASPSLSSTEGPAAPLPLGHCAGQREVCWEQQLRPGGPGPPAAPPPALDA 179

Query: 73  TQLGSFPPLRAPSLSQHPEPGVLRP--DAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQP 130
             L  F   +A  L       VLR   +    L   P + W        PP +    P+P
Sbjct: 180 --LSPFLRKKAQILE------VLRALEETDPLLLCSPATPWR-------PPGQGPGSPEP 224

Query: 131 PPYPLVSPNLLQASPQAPLTCSTPGL---------------GADDLGDGFGPILGP 171
               L  P   + SP AP     PG                G +D G  +GP  GP
Sbjct: 225 INGELCGPPQPEPSPWAPCLLLGPGNLGGLLHWERLLGGLGGEEDTGRPWGPSRGP 280



 Score = 32.7 bits (73), Expect = 0.33
 Identities = 35/120 (29%), Positives = 46/120 (38%), Gaps = 18/120 (15%)

Query: 21   VPG-RPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQKPVLPALLSQTQLGSFP 79
            VPG   L  SG     PA+ AL     G      C         P  P  L++    +FP
Sbjct: 1180 VPGIEELLVSGRHPSMPAFPALLPAAPGHRGHETCPDDPCEDPGPTPPVQLAKNW--TFP 1237

Query: 80   PLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIP------PSRSSPEPQPPPY 133
              RA   S   +P +  P   + L   P++       LP+       PSR SP PQ PP+
Sbjct: 1238 NTRAAGSSS--DPLMCPPRQLEGLPRTPMA-------LPVDRKRSQEPSRPSPTPQGPPF 1288


>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
           sapiens]
          Length = 691

 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 55/225 (24%), Positives = 81/225 (36%), Gaps = 33/225 (14%)

Query: 57  PGGPGQKPVLPALLSQTQLGSF-PPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCL 115
           P    Q+P+ P    Q    S  PP     L Q P+P   +P +  +   QP     S  
Sbjct: 212 PSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSS 271

Query: 116 PLPIP---PSRSSPEPQPPPYPLVSPNLLQASPQAPLTCSTPGLGADDLGDGFGPILGPL 172
           P   P   P    P P  PP PL   N   AS  A    +   + +      FG  L  L
Sbjct: 272 PPQKPSQSPGHGLPSPLTPPNPLQLVNNPLASQAAAAAAAMSSIASSQ---AFGNALSSL 328

Query: 173 VILREPVELDLTAEVVAGV--LPEGGRDPQAAA--------------------QAVSGVI 210
             +   +  +   +++  +  +P  G   QAA+                    Q ++ VI
Sbjct: 329 QGVTGQLVTNAQGQIIGTIPLMPNPGPSSQAASGTQGLQVQPITPQLLTNAQGQIIATVI 388

Query: 211 EGGLLLEGLRVRADPTVHLLPIHPPAQLHVVREEACGQAHQCGLL 255
            G  +L  +  +    + L PI P  QLH   + + GQA   G L
Sbjct: 389 -GNQILPVINTQG---ITLSPIKPGQQLHQPSQTSVGQAASQGNL 429



 Score = 37.4 bits (85), Expect = 0.013
 Identities = 27/75 (36%), Positives = 33/75 (44%), Gaps = 17/75 (22%)

Query: 72  QTQLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQPP 131
           Q Q    PP   PS +QHP+P    P A  +   QPL         P PP +  P  Q P
Sbjct: 190 QQQQQQQPP---PSTNQHPQPA---PQAPSQSQQQPLQ--------PTPPQQPPPASQQP 235

Query: 132 PYPLVSPNLLQASPQ 146
           P P    + LQ +PQ
Sbjct: 236 PAP---TSQLQQAPQ 247


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 46/148 (31%), Positives = 58/148 (39%), Gaps = 24/148 (16%)

Query: 15  PCDAP-GVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQKPVLPALLSQT 73
           P  AP   P  P  S  A+  + A  +L+A  L          P  P   P+ P+     
Sbjct: 672 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV-------PPSPPASPPMSPSATPPP 724

Query: 74  QLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQPPPY 133
           Q    PPL AP L   P P    P +    SA P        P  +PP  ++P  Q PP 
Sbjct: 725 QAP--PPLAAPPLQVPPSPPASPPMSP---SATP--------PPRVPPLLAAPPLQVPPS 771

Query: 134 PLVS---PNLLQASPQAPLTCSTPGLGA 158
           P  S     L +  PQAP   +TP L A
Sbjct: 772 PPASLPMSPLAKPPPQAPPALATPPLQA 799



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 41/155 (26%), Positives = 61/155 (39%), Gaps = 8/155 (5%)

Query: 7   PETRHRNWPCDAPGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQKPVL 66
           P++     P   P  P  PL +S + A +P    L+   L   ++     P  P    ++
Sbjct: 452 PDSPPLQAPLSLPASP--PLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIM 509

Query: 67  PALLSQTQLGSFPPLRAPSLSQHPEP----GVLRPDAQQRLSAQPLSEWGSCLPLPIP-P 121
           P L +Q+ L   P L+ P  S    P      L P   Q  SA   +      P P P P
Sbjct: 510 PPLETQSSLAP-PSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP 568

Query: 122 SRSSPEPQPPPYPLVSPNLLQASPQAPLTCSTPGL 156
            ++ P P   P P    ++    PQAP   ++P L
Sbjct: 569 LQAPPSPLTTPPPETPSSIATPPPQAPPALASPPL 603



 Score = 37.0 bits (84), Expect = 0.017
 Identities = 42/139 (30%), Positives = 51/139 (36%), Gaps = 19/139 (13%)

Query: 19  PGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQK--PVLPALLSQTQLG 76
           P    R  PS+G     PA R+LS+      T        GP  +  P  PA  SQ +  
Sbjct: 220 PSPAARRRPSAGGGLQRPASRSLSSSA----TPLSSPARSGPSARGTPRAPAHPSQPKPK 275

Query: 77  SFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIP-PSRSSPEPQPPPYPL 135
               LR P ++        R DA   L   PLS      PL  P PS +   P PPP   
Sbjct: 276 GLQALRPPQVTPP------RKDAAPALG--PLSS----SPLATPSPSGTKARPVPPPDNA 323

Query: 136 VSPNLLQASPQAPLTCSTP 154
            +P      P  PL    P
Sbjct: 324 ATPLPATLPPSPPLATPLP 342



 Score = 35.8 bits (81), Expect = 0.039
 Identities = 31/103 (30%), Positives = 41/103 (39%), Gaps = 9/103 (8%)

Query: 60  PGQKPVLPALLSQTQLGSFPPLRAPSLSQHPEPGVLRPD-AQQRLSAQPLSEWGSCLPLP 118
           P   P  P L +   L    P   PSL   P P    P  A   ++  P+    S   +P
Sbjct: 328 PATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP 387

Query: 119 ---IPPSRSSPEPQPPPYPLVSPNLLQASPQAPLTCSTPGLGA 158
              +P S +SP  Q PP PL   +L     QA  +  +P L A
Sbjct: 388 PIQVPHSLTSPSLQAPPSPLALSSL-----QATTSLGSPTLQA 425



 Score = 35.8 bits (81), Expect = 0.039
 Identities = 42/143 (29%), Positives = 53/143 (37%), Gaps = 18/143 (12%)

Query: 20  GVPGRPL-PSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQKPVLPALLSQTQLGSF 78
           G+P  PL P +     AP   AL           L + P  P   P+ P      Q    
Sbjct: 605 GLPSPPLSPLATPPPQAPPXLALPP---------LQAPPSPPASPPLSPLATPSPQA--- 652

Query: 79  PPLRAPSLSQHPEPGVLRPDAQQRLS--AQPLSEWGSCLPLPIPPSRSSPEPQPPPYPLV 136
           P   A  L Q P      P  Q   S  A P     +  P   PPS ++P  Q PP P  
Sbjct: 653 PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA 712

Query: 137 SPNLLQAS---PQAPLTCSTPGL 156
           SP +  ++   PQAP   + P L
Sbjct: 713 SPPMSPSATPPPQAPPPLAAPPL 735



 Score = 35.0 bits (79), Expect = 0.066
 Identities = 33/99 (33%), Positives = 40/99 (40%), Gaps = 13/99 (13%)

Query: 64  PVLPALLSQTQLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPI---- 119
           P  PA L  + L   PP   P+L+  P   +  P A     A P S   S    P+    
Sbjct: 770 PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQA-PFSPSASLPMSPLATPP 828

Query: 120 ---PPSRSSPEPQPPPYPLVSPNLLQASPQAPLTCSTPG 155
              PP  ++P  Q PP P  SP L     QAP    TPG
Sbjct: 829 PQAPPVLAAPLLQVPPSPPASPTL-----QAPRRPPTPG 862



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 41/154 (26%), Positives = 52/154 (33%), Gaps = 19/154 (12%)

Query: 15  PCDAPGVPGRPLPSSGASAGAP-AYRALSAGCLGQNTAYLCSQPGGPGQKPVLPALLSQT 73
           P  AP  P    P S  +  +P A  AL+   L    A     P  P Q P  P      
Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLL---QAPFSPPPSPPVQAPFSPPASPPV 685

Query: 74  QLGSFPP------LRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPS----- 122
              + PP      L AP L   P P    P +             +  PL +PPS     
Sbjct: 686 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP 745

Query: 123 ----RSSPEPQPPPYPLVSPNLLQASPQAPLTCS 152
                ++P P+ PP     P  +  SP A L  S
Sbjct: 746 PMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMS 779



 Score = 33.9 bits (76), Expect = 0.15
 Identities = 31/96 (32%), Positives = 38/96 (39%), Gaps = 4/96 (4%)

Query: 66  LPALLSQTQLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLP---IPPS 122
           LP+L       +  PL  P L   P P      A       P  E  S +  P    PP+
Sbjct: 538 LPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPA 597

Query: 123 RSSPEPQPPPYPLVSPNLLQASPQAPLTCSTPGLGA 158
            +SP  Q  P P +SP L    PQAP   + P L A
Sbjct: 598 LASPPLQGLPSPPLSP-LATPPPQAPPXLALPPLQA 632



 Score = 33.1 bits (74), Expect = 0.25
 Identities = 25/71 (35%), Positives = 31/71 (43%), Gaps = 9/71 (12%)

Query: 79  PPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCL-PLPIPPSRSSPEPQPPPYPLVS 137
           PP   P+L+  P  G+  P      +  P +     L PL  PP   SP   PP  PL +
Sbjct: 591 PPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPP---SPPASPPLSPLAT 647

Query: 138 PNLLQASPQAP 148
           P     SPQAP
Sbjct: 648 P-----SPQAP 653


>gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens]
          Length = 1989

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 33/89 (37%), Positives = 40/89 (44%), Gaps = 19/89 (21%)

Query: 55  SQPGGPGQKPVLPALLSQTQLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSE---W 111
           S+   P   PV P   S+  LG F P  APSLS  P P        Q  S  PLS+    
Sbjct: 537 SETSSPAPSPVQPPFFSECSLGYFSP--APSLSLPPPP--------QVSSLPPLSQPYVE 586

Query: 112 GSCLPL-PIPPSRSSP-----EPQPPPYP 134
           G C+ L P+PP    P     +P+ PP P
Sbjct: 587 GLCVSLEPLPPLPPLPPLPPEDPEQPPKP 615


>gi|226437579 NAC alpha domain containing [Homo sapiens]
          Length = 1562

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 38/134 (28%), Positives = 54/134 (40%), Gaps = 19/134 (14%)

Query: 80   PLRAPSLSQHPEP-GVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQPPPYPLVSP 138
            PL+   LS  P+P     P +QQ      L +  S +  P+P   + P   P P  + +P
Sbjct: 887  PLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQ-DSAMTAPLPLQDTGPTSGPEPLAVATP 945

Query: 139  NLLQASPQ-APLTCSTPGLGADDLGDGFGPILGP------LVILREPVELDLTAEVVAGV 191
              LQA    AP T     +   ++G+  GP   P      L  + EP  LD   +     
Sbjct: 946  QTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQ----- 1000

Query: 192  LPEGGRDPQAAAQA 205
                  DPQ AA+A
Sbjct: 1001 -----DDPQPAAEA 1009


>gi|239754540 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1522

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 38/134 (28%), Positives = 54/134 (40%), Gaps = 19/134 (14%)

Query: 80  PLRAPSLSQHPEP-GVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQPPPYPLVSP 138
           PL+   LS  P+P     P +QQ      L +  S +  P+P   + P   P P  + +P
Sbjct: 847 PLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQ-DSAMTAPLPLQDTGPTSGPEPLAVATP 905

Query: 139 NLLQASPQ-APLTCSTPGLGADDLGDGFGPILGP------LVILREPVELDLTAEVVAGV 191
             LQA    AP T     +   ++G+  GP   P      L  + EP  LD   +     
Sbjct: 906 QTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQ----- 960

Query: 192 LPEGGRDPQAAAQA 205
                 DPQ AA+A
Sbjct: 961 -----DDPQPAAEA 969


>gi|239749105 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1522

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 38/134 (28%), Positives = 54/134 (40%), Gaps = 19/134 (14%)

Query: 80  PLRAPSLSQHPEP-GVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQPPPYPLVSP 138
           PL+   LS  P+P     P +QQ      L +  S +  P+P   + P   P P  + +P
Sbjct: 847 PLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQ-DSAMTAPLPLQDTGPTSGPEPLAVATP 905

Query: 139 NLLQASPQ-APLTCSTPGLGADDLGDGFGPILGP------LVILREPVELDLTAEVVAGV 191
             LQA    AP T     +   ++G+  GP   P      L  + EP  LD   +     
Sbjct: 906 QTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQ----- 960

Query: 192 LPEGGRDPQAAAQA 205
                 DPQ AA+A
Sbjct: 961 -----DDPQPAAEA 969


>gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1562

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 38/134 (28%), Positives = 54/134 (40%), Gaps = 19/134 (14%)

Query: 80   PLRAPSLSQHPEP-GVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQPPPYPLVSP 138
            PL+   LS  P+P     P +QQ      L +  S +  P+P   + P   P P  + +P
Sbjct: 887  PLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQ-DSAMTAPLPLQDTGPTSGPEPLAVATP 945

Query: 139  NLLQASPQ-APLTCSTPGLGADDLGDGFGPILGP------LVILREPVELDLTAEVVAGV 191
              LQA    AP T     +   ++G+  GP   P      L  + EP  LD   +     
Sbjct: 946  QTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQ----- 1000

Query: 192  LPEGGRDPQAAAQA 205
                  DPQ AA+A
Sbjct: 1001 -----DDPQPAAEA 1009


>gi|239508792 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1522

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 38/134 (28%), Positives = 54/134 (40%), Gaps = 19/134 (14%)

Query: 80  PLRAPSLSQHPEP-GVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQPPPYPLVSP 138
           PL+   LS  P+P     P +QQ      L +  S +  P+P   + P   P P  + +P
Sbjct: 847 PLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQ-DSAMTAPLPLQDTGPTSGPEPLAVATP 905

Query: 139 NLLQASPQ-APLTCSTPGLGADDLGDGFGPILGP------LVILREPVELDLTAEVVAGV 191
             LQA    AP T     +   ++G+  GP   P      L  + EP  LD   +     
Sbjct: 906 QTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQ----- 960

Query: 192 LPEGGRDPQAAAQA 205
                 DPQ AA+A
Sbjct: 961 -----DDPQPAAEA 969


>gi|209862845 nuclear factor of activated T-cells, cytoplasmic,
           calcineurin-dependent 4 isoform 1 [Homo sapiens]
          Length = 964

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 41/164 (25%), Positives = 62/164 (37%), Gaps = 22/164 (13%)

Query: 3   LAHSPETRHRNWPCDA-PGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPG 61
           L+H+P     ++P ++ PG+P    P  G   GAPA    +A C  +   +         
Sbjct: 28  LSHNPGLSKPDFPGNSSPGLPSSSSP--GRDLGAPAGSMGAASCEDEELEFK-------- 77

Query: 62  QKPVLPALLSQTQLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSC-LPLPIP 120
                   L   +    PPL A  L +  +     P  +  L   P   +G+  + +P P
Sbjct: 78  --------LVFGEEKEAPPLGAGGLGEELDSEDAPPCCRLALGEPP--PYGAAPIGIPRP 127

Query: 121 PSRSSPEPQPPPYPLVSPNLLQASPQAPLTCSTPGLGADDLGDG 164
           P        PPP P  SP   ++ P   +    PG GA   G G
Sbjct: 128 PPPRPGMHSPPPRPAPSPGTWESQPARSVRLGGPGGGAGGAGGG 171



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 49/169 (28%), Positives = 65/169 (38%), Gaps = 21/169 (12%)

Query: 7   PETRHRNWPCDAPGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQKPVL 66
           P++  R +P  +    G  +  S      P+Y      C    T YL S+  G G  P+ 
Sbjct: 757 PDSSLRGFPSASATPFGTDMDFSPPRPPYPSYPHEDPAC---ETPYL-SEGFGYGMPPLY 812

Query: 67  PALLSQTQLGSFPPLRAPSLSQHPEP----GVLRPDAQQRLS----AQPLSEWGSCLPLP 118
           P      Q G  PP   P L   PE     G  +P A   L     + P    GS   L 
Sbjct: 813 P------QTGP-PPSYRPGLRMFPETRGTTGCAQPPAVSFLPRPFPSDPYGGRGSSFSLG 865

Query: 119 IPPSRSSPEPQPPPYPLVSPNLLQASPQAPLTCSTPGLGADDLGDGFGP 167
           +P S  +P  +PPP P  SP L    P        P  G + +G G+GP
Sbjct: 866 LPFSPPAPF-RPPPLP-ASPPLEGPFPSQSDVHPLPAEGYNKVGPGYGP 912


>gi|12751477 forkhead box L2 [Homo sapiens]
          Length = 376

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 45/157 (28%), Positives = 55/157 (35%), Gaps = 25/157 (15%)

Query: 11  HRNWPCDAPGVPGRPLPSS--GASAGAPAYRALSAGCLGQNTAYLCSQPGGPG------- 61
           + +WP   P  P  P  S    A+A A A  A +AG      A +     GP        
Sbjct: 201 NNSWPLPQPPSP-MPYASCQMAAAAAAAAAAAAAAGPGSPGAAAVVKGLAGPAASYGPYT 259

Query: 62  --QKPVLPALLSQTQLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPI 119
             Q   LP  +  +  G   P  AP    HP P    P A    +A          P P 
Sbjct: 260 RVQSMALPPGVVNSYNGLGGPPAAPPPPPHPHP---HPHAHHLHAA--------AAPPPA 308

Query: 120 PPSRSSPEPQPPPYPLVSPNLLQASPQAPLTCSTPGL 156
           PP   +  P P      SP    A+P AP   S PGL
Sbjct: 309 PPHHGAAAPPPGQLSPASP--ATAAPPAPAPTSAPGL 343


>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
            RhoGEF isoform b [Homo sapiens]
          Length = 7968

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 49/196 (25%), Positives = 68/196 (34%), Gaps = 24/196 (12%)

Query: 84   PSLSQHPEPGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQPPPYPLVSPNLLQA 143
            PS   HP  G  +P+        P S WG   P   P   S+P+    P+P V+P    +
Sbjct: 7008 PSTGGHP--GTAQPERPS-----PDSPWGQPAPFCHPKQGSAPQEGCSPHPAVAPCPPGS 7060

Query: 144  SP-----QAPLTCSTPGLGADDLGDGFGPILGPLVILREPVELDLTAEVVAGVLPEGGRD 198
             P     +APL  S+P LG             PL     P ++ L      G     G  
Sbjct: 7061 FPPGSCKEAPLVPSSPFLGQPQAPPAPAKASPPLDSKMGPGDISLPGRPKPGPCSSPGSA 7120

Query: 199  PQAAAQAVSGVIEG----------GLLLEGLRVRADPTVHLLPI--HPPAQLHVVREEAC 246
             QA++  VS +  G           L  EG    A+      P    P  Q  + +    
Sbjct: 7121 SQASSSQVSSLRVGSSQVGTEPGPSLDAEGWTQEAEDLSDSTPTLQRPQEQATMRKFSLG 7180

Query: 247  GQAHQCGLLGVGDLCF 262
            G+    G+ G G   F
Sbjct: 7181 GRGGYAGVAGYGTFAF 7196



 Score = 29.6 bits (65), Expect = 2.8
 Identities = 29/92 (31%), Positives = 40/92 (43%), Gaps = 11/92 (11%)

Query: 43   AGCLGQNTAYLCSQPGGP-GQKPVLPAL---LSQTQLGSFPPLRAPSLSQHPEPGVLRPD 98
            AG  G  T       GG  GQ P+   +   +SQ++       RA S S+  +       
Sbjct: 7186 AGVAGYGTFAFGGDAGGMLGQGPMWARIAWAVSQSEEEEQEEARAESQSEEQQEARAESP 7245

Query: 99   AQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQP 130
              Q +SA+P+ E G        P+RSSPEP P
Sbjct: 7246 LPQ-VSARPVPEVGRA------PTRSSPEPTP 7270


>gi|239757987 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 445

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 45/140 (32%), Positives = 59/140 (42%), Gaps = 26/140 (18%)

Query: 22  PGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQKPVLPALLSQTQLGSFPPL 81
           PGR  PS G  +GA    A +   LG   + + + PG P + P  P           PPL
Sbjct: 190 PGRSGPSGGVRSGAGHRAATAEHQLGAGFS-VRNGPGPPARLPPAPP---------GPPL 239

Query: 82  RAPSLSQHPE---PGVLRPDAQQRLSAQPLSEWGSCLPLPIPPSRSSPEPQPPPYPLVSP 138
           R P+   +P    PG L       L+ +P S     LP P+P  RS     PPP   V P
Sbjct: 240 R-PARPHNPTSRGPGRL-------LTCEPPSRK---LPPPLPLCRSRWVLAPPP--TVRP 286

Query: 139 NLLQASPQAPLTCSTPGLGA 158
            L   +P   L C+ P  G+
Sbjct: 287 RLRVLTPPFTLLCALPERGS 306



 Score = 34.7 bits (78), Expect = 0.087
 Identities = 30/89 (33%), Positives = 35/89 (39%), Gaps = 6/89 (6%)

Query: 105 AQPLSEWGSCLPLPIPPS--RSSPEPQPPPYPLVSPNLLQASPQAPLTCSTPGLGADDLG 162
           A P   + S  PLP PPS   S P PQ     +  P LL+A+    L    P       G
Sbjct: 348 AAPTRAFCSADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAA----LALGAPRGRTPSPG 403

Query: 163 DGFGPILGPLVILREPVELDLTAEVVAGV 191
            G  P L P  + R P  L L   V   V
Sbjct: 404 PGPAPALQPYSLTRFPASLSLPDLVFTSV 432



 Score = 29.6 bits (65), Expect = 2.8
 Identities = 43/154 (27%), Positives = 49/154 (31%), Gaps = 19/154 (12%)

Query: 15  PCDAPGVPG-RPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQ-KPV---LPAL 69
           P + PG PG + L  S A           A   G+N       P  PG  +P     PA 
Sbjct: 113 PYEGPGAPGGQQLRKSRARLPRTRPGREDAAVRGRNR-----DPAEPGSLRPTSLGFPAR 167

Query: 70  LSQTQLGSFPPLRAPSLSQHPEPGVLRPDAQQRLSA--------QPLSEWGSCLPLPIPP 121
             Q Q+    P R         PG   P    R  A          L    S    P PP
Sbjct: 168 AGQGQVQGAAPGRRLRGEPKTPPGRSGPSGGVRSGAGHRAATAEHQLGAGFSVRNGPGPP 227

Query: 122 SRSSPEPQPPPYPLVSP-NLLQASPQAPLTCSTP 154
           +R  P P  PP     P N     P   LTC  P
Sbjct: 228 ARLPPAPPGPPLRPARPHNPTSRGPGRLLTCEPP 261


>gi|239755710 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 402

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 45/151 (29%), Positives = 63/151 (41%), Gaps = 23/151 (15%)

Query: 19  PGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQKPVLPALLSQTQLGSF 78
           PG  G      G S+GA   R       G+  A   +   G GQ+P   +L   ++ G+ 
Sbjct: 125 PGKAGCRTRLQGGSSGASPRRLPG----GRGPAAAFAVEPGTGQRPRNTSLAQASRSGTV 180

Query: 79  P--------PLRAPSLSQHPEPGVLRPDAQ---QRLSAQPLSEWGSCLPLPIPPSRSSPE 127
           P        PLR P L+    PG   P ++   + L+ +P S     LP P+PP RS   
Sbjct: 181 PGLPPASLQPLRLPYLAP---PGPHDPTSRGPGRLLTCEPPSRK---LPPPLPPCRSRWV 234

Query: 128 PQPPPYPLVSPNLLQASPQAPLTCSTPGLGA 158
             PP  P V P L   +P   L  + P  G+
Sbjct: 235 LAPP--PTVRPRLRVLTPPLALRRALPERGS 263



 Score = 35.4 bits (80), Expect = 0.051
 Identities = 30/89 (33%), Positives = 35/89 (39%), Gaps = 6/89 (6%)

Query: 105 AQPLSEWGSCLPLPIPPS--RSSPEPQPPPYPLVSPNLLQASPQAPLTCSTPGLGADDLG 162
           A P   + S  PLP PPS   S P PQ     +  P LL+A+    L    P       G
Sbjct: 305 AAPTRAFCSADPLPRPPSFVPSLPSPQAQGQAVRQPRLLRAA----LALGAPRGRTPSPG 360

Query: 163 DGFGPILGPLVILREPVELDLTAEVVAGV 191
            G  P L P  + R P  L L   V   V
Sbjct: 361 PGPAPALQPYTLTRFPASLSLPDLVFTSV 389


>gi|21389357 MAPK-interacting and spindle-stabilizing protein [Homo
           sapiens]
          Length = 245

 Score = 39.7 bits (91), Expect = 0.003
 Identities = 41/143 (28%), Positives = 46/143 (32%), Gaps = 45/143 (31%)

Query: 15  PCDAPGVPGRPLPSSGASAGAPAYRALSAGCLGQNTAYLCSQPGGPGQKPVLPALLSQTQ 74
           P   P  P  P P SG S                     C  PGGP   P +P       
Sbjct: 77  PTGPPPGPPAPFPPSGPS---------------------CPPPGGPYPAPTVPGP----- 110

Query: 75  LGSFPPLRAPSLSQHPEPGVLRPDAQQR--LSAQPLSEWGSCLPLPIPPSRSS------- 125
            G   P   P++   P P + RP        +A PL  WGS    P  P           
Sbjct: 111 -GPTGPYPTPNM---PFPELPRPYGAPTDPAAAGPLGPWGSMSSGPWAPGMGGQYPTPNM 166

Query: 126 PEPQPPPYPLVSPNLLQASPQAP 148
           P P P PYP   P      PQAP
Sbjct: 167 PYPSPGPYPAPPP------PQAP 183


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.138    0.440 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,781,177
Number of Sequences: 37866
Number of extensions: 1000959
Number of successful extensions: 10723
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 192
Number of HSP's successfully gapped in prelim test: 810
Number of HSP's that attempted gapping in prelim test: 6944
Number of HSP's gapped (non-prelim): 3044
length of query: 262
length of database: 18,247,518
effective HSP length: 100
effective length of query: 162
effective length of database: 14,460,918
effective search space: 2342668716
effective search space used: 2342668716
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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