Search of human proteins with 239749012

Search of human proteins with 239749012

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239749012 PREDICTED: hypothetical protein XP_002346880 [Homo
sapiens]
         (414 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239749012 PREDICTED: hypothetical protein XP_002346880 [Homo ...   842   0.0  
gi|130980075 centromere protein J [Homo sapiens]                      204   2e-52
gi|56549668 AT rich interactive domain 2 (ARID, RFX-like) [Homo ...    31   1.8  
gi|60498992 forkhead box P4 isoform 3 [Homo sapiens]                   31   2.4  
gi|60498989 forkhead box P4 isoform 1 [Homo sapiens]                   31   2.4  
gi|168693647 endoglin isoform 1 precursor [Homo sapiens]               30   4.0  
gi|4557555 endoglin isoform 2 precursor [Homo sapiens]                 30   4.0  
gi|54633319 PDZ domain-containing guanine nucleotide exchange fa...    30   4.0  
gi|29789367 forkhead box P4 isoform 2 [Homo sapiens]                   30   4.0  
gi|71902540 ataxia telangiectasia mutated isoform 1 [Homo sapiens]     29   6.9  
gi|169218268 PREDICTED: similar to Serine-protein kinase ATM, pa...    29   6.9  
gi|239752520 PREDICTED: similar to Rap guanine nucleotide exchan...    29   6.9  
gi|7657261 Rap guanine nucleotide exchange factor 2 [Homo sapiens]     29   6.9  
gi|150417973 supervillin isoform 2 [Homo sapiens]                      29   9.0  

>gi|239749012 PREDICTED: hypothetical protein XP_002346880 [Homo
           sapiens]
          Length = 414

 Score =  842 bits (2174), Expect = 0.0
 Identities = 414/414 (100%), Positives = 414/414 (100%)

Query: 1   MKHLPRGRSQGLQDLSSSLVRALELVSIEDYGAHALGGQKLRKENSTLEEFAEERLKVDS 60
           MKHLPRGRSQGLQDLSSSLVRALELVSIEDYGAHALGGQKLRKENSTLEEFAEERLKVDS
Sbjct: 1   MKHLPRGRSQGLQDLSSSLVRALELVSIEDYGAHALGGQKLRKENSTLEEFAEERLKVDS 60

Query: 61  PTIENCIWLHKAQVQLLGVDGIWGRFVHPLGICLYPVQSVVLSPWHLVSHAADPVRRRGD 120
           PTIENCIWLHKAQVQLLGVDGIWGRFVHPLGICLYPVQSVVLSPWHLVSHAADPVRRRGD
Sbjct: 61  PTIENCIWLHKAQVQLLGVDGIWGRFVHPLGICLYPVQSVVLSPWHLVSHAADPVRRRGD 120

Query: 121 SPLCGPLLCAATQPPPSSLAGNVRPILTQVPLRHQSLIDLRNHFCPRRSKVECLNFERTI 180
           SPLCGPLLCAATQPPPSSLAGNVRPILTQVPLRHQSLIDLRNHFCPRRSKVECLNFERTI
Sbjct: 121 SPLCGPLLCAATQPPPSSLAGNVRPILTQVPLRHQSLIDLRNHFCPRRSKVECLNFERTI 180

Query: 181 IRPTLYLQVYVLKKSSSPIRTVFAQLLADKHSDPDVSREDEQSDPDVSQDDKSQILKSMT 240
           IRPTLYLQVYVLKKSSSPIRTVFAQLLADKHSDPDVSREDEQSDPDVSQDDKSQILKSMT
Sbjct: 181 IRPTLYLQVYVLKKSSSPIRTVFAQLLADKHSDPDVSREDEQSDPDVSQDDKSQILKSMT 240

Query: 241 EHIIRFSNGDVKKIKPSRRVIYYHANAQTMRTTYPDGLEVVQFPNKQTEKFYPNGSKEIV 300
           EHIIRFSNGDVKKIKPSRRVIYYHANAQTMRTTYPDGLEVVQFPNKQTEKFYPNGSKEIV
Sbjct: 241 EHIIRFSNGDVKKIKPSRRVIYYHANAQTMRTTYPDGLEVVQFPNKQTEKFYPNGSKEIV 300

Query: 301 FPDGTVEHLKDGQEETLFPDGTIVRVERNGDKTIVLSNGQKEIHTARFKRREYPDGTVKT 360
           FPDGTVEHLKDGQEETLFPDGTIVRVERNGDKTIVLSNGQKEIHTARFKRREYPDGTVKT
Sbjct: 301 FPDGTVEHLKDGQEETLFPDGTIVRVERNGDKTIVLSNGQKEIHTARFKRREYPDGTVKT 360

Query: 361 VYCSGCQETKYASGRVKIKDEAGNVVLDEKQMSPQHAASHGKCQLQIFAKTDKN 414
           VYCSGCQETKYASGRVKIKDEAGNVVLDEKQMSPQHAASHGKCQLQIFAKTDKN
Sbjct: 361 VYCSGCQETKYASGRVKIKDEAGNVVLDEKQMSPQHAASHGKCQLQIFAKTDKN 414


>gi|130980075 centromere protein J [Homo sapiens]
          Length = 1338

 Score =  204 bits (518), Expect = 2e-52
 Identities = 95/146 (65%), Positives = 122/146 (83%), Gaps = 1/146 (0%)

Query: 244  IRFSNGDVKKIKPSRRVIYYHANAQTMRTTYPDGLEVVQFPNKQTEKFYPNGSKEIVFPD 303
            + F NGDVK++ P +RVIYY+A AQT  TTYP+GLEV+ F + Q EK YP+G KEI FPD
Sbjct: 1190 VTFFNGDVKQVMPDQRVIYYYAAAQTTHTTYPEGLEVLHFSSGQIEKHYPDGRKEITFPD 1249

Query: 304  GTVEHL-KDGQEETLFPDGTIVRVERNGDKTIVLSNGQKEIHTARFKRREYPDGTVKTVY 362
             TV++L  DGQEE++FPDGTIVRV+R+G+K I  +NGQ+E+HTA+FKRREYPDGTVKTVY
Sbjct: 1250 QTVKNLFPDGQEESIFPDGTIVRVQRDGNKLIEFNNGQRELHTAQFKRREYPDGTVKTVY 1309

Query: 363  CSGCQETKYASGRVKIKDEAGNVVLD 388
             +G QETKY SGR+++KD+ GNV++D
Sbjct: 1310 ANGHQETKYRSGRIRVKDKEGNVLMD 1335



 Score = 29.6 bits (65), Expect = 5.2
 Identities = 24/101 (23%), Positives = 44/101 (43%), Gaps = 24/101 (23%)

Query: 301  FPDGTVEHLKDGQE---ETLFPDGTIVRVERNGDKTIVLSNGQKEIHTARFK-------- 349
            FPD   +  ++ Q+   E   PDG + +V +NG + I+  NG ++  +A  K        
Sbjct: 1135 FPDPEYKEEEEDQDIQGEISHPDGKVEKVYKNGCRVILFPNGTRKEVSADGKTITVTFFN 1194

Query: 350  ---RREYPD----------GTVKTVYCSGCQETKYASGRVK 377
               ++  PD           T  T Y  G +   ++SG+++
Sbjct: 1195 GDVKQVMPDQRVIYYYAAAQTTHTTYPEGLEVLHFSSGQIE 1235


>gi|56549668 AT rich interactive domain 2 (ARID, RFX-like) [Homo
           sapiens]
          Length = 1835

 Score = 31.2 bits (69), Expect = 1.8
 Identities = 17/39 (43%), Positives = 21/39 (53%), Gaps = 6/39 (15%)

Query: 316 TLFPDGTIVRVERNGDKTIVLSNGQKEIHTARFKRREYP 354
           T+FP+ T+ RVE +       SNGQ  IH    KRR  P
Sbjct: 573 TVFPNHTVKRVEDSS------SNGQAHIHVVGVKRRAIP 605


>gi|60498992 forkhead box P4 isoform 3 [Homo sapiens]
          Length = 678

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 28/106 (26%), Positives = 39/106 (36%), Gaps = 15/106 (14%)

Query: 72  AQVQLLGVDGIWGRFVHPLGICLYPVQSVVLSPWHLVS---HAADPVRRRGDSPLCGPLL 128
           ++V +   D      VHP      PV    L P  L S   H   P RRR     C P+ 
Sbjct: 392 SKVTVSAADSFPDGLVHPPTSAAAPVTP--LRPPGLGSASLHGGGPARRRSSDKFCSPIS 449

Query: 129 CAATQ----------PPPSSLAGNVRPILTQVPLRHQSLIDLRNHF 164
               Q           PP + A  +R  + + P R  +L ++ N F
Sbjct: 450 SELAQNHEFYKNADVRPPFTYASLIRQAILETPDRQLTLNEIYNWF 495


>gi|60498989 forkhead box P4 isoform 1 [Homo sapiens]
          Length = 680

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 28/106 (26%), Positives = 39/106 (36%), Gaps = 15/106 (14%)

Query: 72  AQVQLLGVDGIWGRFVHPLGICLYPVQSVVLSPWHLVS---HAADPVRRRGDSPLCGPLL 128
           ++V +   D      VHP      PV    L P  L S   H   P RRR     C P+ 
Sbjct: 394 SKVTVSAADSFPDGLVHPPTSAAAPVTP--LRPPGLGSASLHGGGPARRRSSDKFCSPIS 451

Query: 129 CAATQ----------PPPSSLAGNVRPILTQVPLRHQSLIDLRNHF 164
               Q           PP + A  +R  + + P R  +L ++ N F
Sbjct: 452 SELAQNHEFYKNADVRPPFTYASLIRQAILETPDRQLTLNEIYNWF 497


>gi|168693647 endoglin isoform 1 precursor [Homo sapiens]
          Length = 658

 Score = 30.0 bits (66), Expect = 4.0
 Identities = 12/46 (26%), Positives = 28/46 (60%)

Query: 152 LRHQSLIDLRNHFCPRRSKVECLNFERTIIRPTLYLQVYVLKKSSS 197
           + +++++++ +   P+R KV CLN +    +  LYL  + L+ S++
Sbjct: 421 ISNEAVVNILSSSSPQRKKVHCLNMDSLSFQLGLYLSPHFLQASNT 466


>gi|4557555 endoglin isoform 2 precursor [Homo sapiens]
          Length = 625

 Score = 30.0 bits (66), Expect = 4.0
 Identities = 12/46 (26%), Positives = 28/46 (60%)

Query: 152 LRHQSLIDLRNHFCPRRSKVECLNFERTIIRPTLYLQVYVLKKSSS 197
           + +++++++ +   P+R KV CLN +    +  LYL  + L+ S++
Sbjct: 421 ISNEAVVNILSSSSPQRKKVHCLNMDSLSFQLGLYLSPHFLQASNT 466


>gi|54633319 PDZ domain-containing guanine nucleotide exchange
           factor I [Homo sapiens]
          Length = 1601

 Score = 30.0 bits (66), Expect = 4.0
 Identities = 30/108 (27%), Positives = 49/108 (45%), Gaps = 12/108 (11%)

Query: 215 DVSREDEQSDP-DVSQDDKSQILKSMTEHIIRFSNGDVKKIKPSRRVIYYHANAQTMRTT 273
           D+ RE  + +P D + DD  Q+L+ M + +  F+N  +   +    V+ +    Q     
Sbjct: 250 DLVRECLEKEPADKTDDDIEQLLEFMHQ-LPAFANMTMSVRRELCSVMIFEVVEQAGAII 308

Query: 274 YPDGLEVVQFPNKQTEKFYP--NGSKEIVFPDGTVEHLKDGQEETLFP 319
             DG E+        + +Y   NG+ EI  PDG VE+L  G    + P
Sbjct: 309 LEDGQEL--------DSWYVILNGTVEISHPDGKVENLFMGNSFGITP 348


>gi|29789367 forkhead box P4 isoform 2 [Homo sapiens]
          Length = 667

 Score = 30.0 bits (66), Expect = 4.0
 Identities = 28/104 (26%), Positives = 37/104 (35%), Gaps = 15/104 (14%)

Query: 74  VQLLGVDGIWGRFVHPLGICLYPVQSVVLSPWHLVS---HAADPVRRRGDSPLCGPLLCA 130
           V +   D      VHP      PV    L P  L S   H   P RRR     C P+   
Sbjct: 383 VTVSAADSFPDGLVHPPTSAAAPVTP--LRPPGLGSASLHGGGPARRRSSDKFCSPISSE 440

Query: 131 ATQ----------PPPSSLAGNVRPILTQVPLRHQSLIDLRNHF 164
             Q           PP + A  +R  + + P R  +L ++ N F
Sbjct: 441 LAQNHEFYKNADVRPPFTYASLIRQAILETPDRQLTLNEIYNWF 484


>gi|71902540 ataxia telangiectasia mutated isoform 1 [Homo sapiens]
          Length = 3056

 Score = 29.3 bits (64), Expect = 6.9
 Identities = 31/118 (26%), Positives = 51/118 (43%), Gaps = 12/118 (10%)

Query: 164  FCPRRSKVECLNFERTIIRPTLYLQVYVLKKSSS--PIRTVFAQLLADKHSDPDVSREDE 221
            F  R + V CL   +T++    Y +  +L       P+  VF Q LAD H    V     
Sbjct: 1036 FSVRMALVNCL---KTLLEADPYSKWAILNVMGKDFPVNEVFTQFLADNHH--QVRMLAA 1090

Query: 222  QSDPDVSQD---DKSQILKSMTEHI--IRFSNGDVKKIKPSRRVIYYHANAQTMRTTY 274
            +S   + QD   D S++LK++   +    F N  +K  +  R + +   N +T+   Y
Sbjct: 1091 ESINRLFQDTKGDSSRLLKALPLKLQQTAFENAYLKAQEGMREMSHSAENPETLDEIY 1148


>gi|169218268 PREDICTED: similar to Serine-protein kinase ATM, partial
            [Homo sapiens]
          Length = 2934

 Score = 29.3 bits (64), Expect = 6.9
 Identities = 31/118 (26%), Positives = 51/118 (43%), Gaps = 12/118 (10%)

Query: 164  FCPRRSKVECLNFERTIIRPTLYLQVYVLKKSSS--PIRTVFAQLLADKHSDPDVSREDE 221
            F  R + V CL   +T++    Y +  +L       P+  VF Q LAD H    V     
Sbjct: 914  FSVRMALVNCL---KTLLEADPYSKWAILNVMGKDFPVNEVFTQFLADNHH--QVRMLAA 968

Query: 222  QSDPDVSQD---DKSQILKSMTEHI--IRFSNGDVKKIKPSRRVIYYHANAQTMRTTY 274
            +S   + QD   D S++LK++   +    F N  +K  +  R + +   N +T+   Y
Sbjct: 969  ESINRLFQDTKGDSSRLLKALPLKLQQTAFENAYLKAQEGMREMSHSAENPETLDEIY 1026


>gi|239752520 PREDICTED: similar to Rap guanine nucleotide exchange
           factor 2, partial [Homo sapiens]
          Length = 803

 Score = 29.3 bits (64), Expect = 6.9
 Identities = 30/116 (25%), Positives = 51/116 (43%), Gaps = 12/116 (10%)

Query: 209 DKHSDP----DVSREDEQSDP-DVSQDDKSQILKSMTEHIIRFSNGDVKKIKPSRRVIYY 263
           ++ SDP    D+ R+  + DP D + DD  Q+L+ M + +  F+N  +   +    V+ +
Sbjct: 95  ERASDPLMSRDIVRDCLEKDPIDRTDDDIEQLLEFMHQ-LPAFANMTMSVRRELCAVMVF 153

Query: 264 HANAQTMRTTYPDGLEVVQFPNKQTEKFYPNGSKEIVFPDGTVEHLKDGQEETLFP 319
               +       DG E+  +          NGS E+ +PDG  E L  G    + P
Sbjct: 154 AVVERAGTIVLNDGEELDSW------SVILNGSVEVTYPDGKAEILCMGNSFGVSP 203


>gi|7657261 Rap guanine nucleotide exchange factor 2 [Homo sapiens]
          Length = 1499

 Score = 29.3 bits (64), Expect = 6.9
 Identities = 30/116 (25%), Positives = 51/116 (43%), Gaps = 12/116 (10%)

Query: 209 DKHSDP----DVSREDEQSDP-DVSQDDKSQILKSMTEHIIRFSNGDVKKIKPSRRVIYY 263
           ++ SDP    D+ R+  + DP D + DD  Q+L+ M + +  F+N  +   +    V+ +
Sbjct: 95  ERASDPLMSRDIVRDCLEKDPIDRTDDDIEQLLEFMHQ-LPAFANMTMSVRRELCAVMVF 153

Query: 264 HANAQTMRTTYPDGLEVVQFPNKQTEKFYPNGSKEIVFPDGTVEHLKDGQEETLFP 319
               +       DG E+  +          NGS E+ +PDG  E L  G    + P
Sbjct: 154 AVVERAGTIVLNDGEELDSW------SVILNGSVEVTYPDGKAEILCMGNSFGVSP 203


>gi|150417973 supervillin isoform 2 [Homo sapiens]
          Length = 2214

 Score = 28.9 bits (63), Expect = 9.0
 Identities = 14/42 (33%), Positives = 24/42 (57%), Gaps = 5/42 (11%)

Query: 115 VRRRGDSPLCGPL-----LCAATQPPPSSLAGNVRPILTQVP 151
           +RR  D  L  P+     + AAT+P P+S +G   P++ ++P
Sbjct: 727 LRRLQDRSLTQPITTEEVVIAATEPIPASCSGGTHPVMARLP 768


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,664,927
Number of Sequences: 37866
Number of extensions: 777937
Number of successful extensions: 2007
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1974
Number of HSP's gapped (non-prelim): 21
length of query: 414
length of database: 18,247,518
effective HSP length: 105
effective length of query: 309
effective length of database: 14,271,588
effective search space: 4409920692
effective search space used: 4409920692
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.