BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239747014 PREDICTED: similar to tektin 4 [Homo sapiens] (507 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239747014 PREDICTED: similar to tektin 4 [Homo sapiens] 1032 0.0 gi|239747088 PREDICTED: MAFF interacting protein [Homo sapiens] 634 0.0 gi|21389613 tektin 4 [Homo sapiens] 534 e-152 gi|239752581 PREDICTED: MAFF interacting protein [Homo sapiens] 417 e-116 gi|239758055 PREDICTED: similar to tektin 4 [Homo sapiens] 346 3e-95 gi|75677606 hypothetical protein LOC100132288 [Homo sapiens] 214 1e-55 gi|13994250 tektin 3 [Homo sapiens] 171 2e-42 gi|16753231 tektin 1 [Homo sapiens] 167 2e-41 gi|21389569 tektin 5 [Homo sapiens] 125 7e-29 gi|16507950 tektin 2 [Homo sapiens] 82 9e-16 gi|169209613 PREDICTED: hypothetical protein LOC100128785 [Homo ... 68 2e-11 gi|169210642 PREDICTED: hypothetical protein LOC100128785 [Homo ... 68 2e-11 gi|169210176 PREDICTED: hypothetical protein LOC100128785 [Homo ... 68 2e-11 gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 45 2e-04 gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 43 8e-04 gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens] 42 0.001 gi|122937396 coiled-coil domain containing 150 [Homo sapiens] 40 0.004 gi|4504063 golgin 97 [Homo sapiens] 39 0.011 gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 39 0.011 gi|81295809 pericentrin [Homo sapiens] 38 0.019 gi|169211436 PREDICTED: hypothetical protein [Homo sapiens] 38 0.025 gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 38 0.025 gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi... 37 0.042 gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapi... 37 0.042 gi|115527097 CDC42-binding protein kinase beta [Homo sapiens] 37 0.055 gi|21735548 centrosomal protein 2 [Homo sapiens] 36 0.094 gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 36 0.094 gi|4759082 serum deprivation response protein [Homo sapiens] 35 0.12 gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 35 0.21 gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 35 0.21 >gi|239747014 PREDICTED: similar to tektin 4 [Homo sapiens] Length = 507 Score = 1032 bits (2669), Expect = 0.0 Identities = 507/507 (100%), Positives = 507/507 (100%) Query: 1 MVQTDMLLPEPAPQTVPPCELPCKEYDVAFADCNQSERELQGHKSQQLAAEIQALAQPTQ 60 MVQTDMLLPEPAPQTVPPCELPCKEYDVAFADCNQSERELQGHKSQQLAAEIQALAQPTQ Sbjct: 1 MVQTDMLLPEPAPQTVPPCELPCKEYDVAFADCNQSERELQGHKSQQLAAEIQALAQPTQ 60 Query: 61 QDSKCRVGERLQDMHSWNSELQGEVEALAAETDLLLAQKQRLEHALDAMEVPFSIATDNM 120 QDSKCRVGERLQDMHSWNSELQGEVEALAAETDLLLAQKQRLEHALDAMEVPFSIATDNM Sbjct: 61 QDSKCRVGERLQDMHSWNSELQGEVEALAAETDLLLAQKQRLEHALDAMEVPFSIATDNM 120 Query: 121 QCNQRHQHANLVRDHVETELLKAYPPAPSQCLKNCCSSRKPSASNKGVCEVMETLTVQEE 180 QCNQRHQHANLVRDHVETELLKAYPPAPSQCLKNCCSSRKPSASNKGVCEVMETLTVQEE Sbjct: 121 QCNQRHQHANLVRDHVETELLKAYPPAPSQCLKNCCSSRKPSASNKGVCEVMETLTVQEE 180 Query: 181 ANPGTEGCRTRALAHKEEAELIRNIQELLKRVIVQAVSQIRLNREHMEICEMDWSDKVEA 240 ANPGTEGCRTRALAHKEEAELIRNIQELLKRVIVQAVSQIRLNREHMEICEMDWSDKVEA Sbjct: 181 ANPGTEGCRTRALAHKEEAELIRNIQELLKRVIVQAVSQIRLNREHMEICEMDWSDKVEA 240 Query: 241 YNLDETCGRHRSQSTEPRSASTPETRTKFTQDNLCRAQRERLDSANLWVLVDCILRDTSE 300 YNLDETCGRHRSQSTEPRSASTPETRTKFTQDNLCRAQRERLDSANLWVLVDCILRDTSE Sbjct: 241 YNLDETCGRHRSQSTEPRSASTPETRTKFTQDNLCRAQRERLDSANLWVLVDCILRDTSE 300 Query: 301 DLGLQCDAVNLAFGRRCEELEDARHKLQHHLQKMLREITDQEHNMVALKEAIKDKEAPLH 360 DLGLQCDAVNLAFGRRCEELEDARHKLQHHLQKMLREITDQEHNMVALKEAIKDKEAPLH Sbjct: 301 DLGLQCDAVNLAFGRRCEELEDARHKLQHHLQKMLREITDQEHNMVALKEAIKDKEAPLH 360 Query: 361 IAQTRLYLLSHRPNMELCRDAAQFRYRHDTGQVMGRGPPSARDLCPRGLTPPSATSSSQE 420 IAQTRLYLLSHRPNMELCRDAAQFRYRHDTGQVMGRGPPSARDLCPRGLTPPSATSSSQE Sbjct: 361 IAQTRLYLLSHRPNMELCRDAAQFRYRHDTGQVMGRGPPSARDLCPRGLTPPSATSSSQE 420 Query: 421 EAPSDKPQLTPPNTPKLVSELEELYKSITALWEKLLQAEQSLHNLEDIHMSLEKDVTAMT 480 EAPSDKPQLTPPNTPKLVSELEELYKSITALWEKLLQAEQSLHNLEDIHMSLEKDVTAMT Sbjct: 421 EAPSDKPQLTPPNTPKLVSELEELYKSITALWEKLLQAEQSLHNLEDIHMSLEKDVTAMT 480 Query: 481 NSLFLDRQNCMAHHTCYPTILQLAGYQ 507 NSLFLDRQNCMAHHTCYPTILQLAGYQ Sbjct: 481 NSLFLDRQNCMAHHTCYPTILQLAGYQ 507 >gi|239747088 PREDICTED: MAFF interacting protein [Homo sapiens] Length = 445 Score = 634 bits (1636), Expect = 0.0 Identities = 358/551 (64%), Positives = 375/551 (68%), Gaps = 150/551 (27%) Query: 1 MVQTDMLLPEPAPQTVPPCELPCKEYDVA------------------------------F 30 MVQTD+LLPE APQTVPP ELPCKEYDVA F Sbjct: 1 MVQTDVLLPELAPQTVPPYELPCKEYDVARNTGAYTSSGLATAXLEVWFQNCYARYRQAF 60 Query: 31 ADCNQSERELQGHKSQQLAAEIQALAQPTQQDSKCRVGERLQDMHSWNSELQGEVEALAA 90 A+CNQSERELQGH+SQQLAAE QALAQPTQQDS CRVGERLQD +SW SELQ EVEALAA Sbjct: 61 ANCNQSERELQGHESQQLAAETQALAQPTQQDSTCRVGERLQDTNSWKSELQREVEALAA 120 Query: 91 ETDLLLAQKQRLEHALDAMEVPFSIATDNMQCNQRHQHANLVRDHVETELLKAYPPAPSQ 150 ETDLLLAQKQRLE ALDAMEVPFSI TDNMQC+QRHQH T LL+ + ++ Sbjct: 121 ETDLLLAQKQRLERALDAMEVPFSITTDNMQCSQRHQH---------TNLLRDH--VETE 169 Query: 151 CLKNCCSSRKPSASNKGVCEVMETLTVQEEANPGTEGCRTRALAHKEEAELIRNIQELLK 210 LK EAELIRNIQELLK Sbjct: 170 LLK--------------------------------------------EAELIRNIQELLK 185 Query: 211 RVIVQAVSQIRLNREHMEICEMDWSDKVEAYNLDETCGRHRSQSTE-------------- 256 R I+QAVSQI LN EHMEICEMDWSDKVEAYNLD+TCGRH SQSTE Sbjct: 186 RAIMQAVSQIXLNXEHMEICEMDWSDKVEAYNLDKTCGRHHSQSTEVQAHPHSTTFQERG 245 Query: 257 PRSASTPETRTKFTQDNLCRAQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGRR 316 PRSASTPETRTKFTQDNLC AQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGRR Sbjct: 246 PRSASTPETRTKFTQDNLCHAQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGRR 305 Query: 317 CEELEDARHKLQHHLQKMLREITDQEHNMVALKEAIKDKEAPLHIAQTRLYLLSHRPNME 376 CEELEDARHKLQHHL KMLREITDQEHN+VALKEAIKDKE PLHIAQTRL LLSHRPNM+ Sbjct: 306 CEELEDARHKLQHHLHKMLREITDQEHNVVALKEAIKDKEEPLHIAQTRLXLLSHRPNMQ 365 Query: 377 LCRDAAQFRYRHDTGQVMGRGPPSARDLCPRGLTPPSATSSSQEEAPSDKPQLTPPNTPK 436 LCRDAAQFR Sbjct: 366 LCRDAAQFR--------------------------------------------------- 374 Query: 437 LVSELEELYKSITALWEKLLQAEQSLHNLEDIHMSLEKDVTAMTNSLFLDRQNCMAHHTC 496 LVSE+EELYKSITAL EKLLQAEQSL NL+DIHMSLEKDVTAMTNS+F+DRQ CMAH TC Sbjct: 375 LVSEVEELYKSITALREKLLQAEQSLRNLKDIHMSLEKDVTAMTNSVFIDRQKCMAHRTC 434 Query: 497 YPTILQLAGYQ 507 YPTILQLAGYQ Sbjct: 435 YPTILQLAGYQ 445 >gi|21389613 tektin 4 [Homo sapiens] Length = 435 Score = 534 bits (1375), Expect = e-152 Identities = 316/541 (58%), Positives = 338/541 (62%), Gaps = 155/541 (28%) Query: 14 QTVPPCELPCKEYDVA-------------------------------------FADCNQS 36 QTVPPCELPCKEYDVA FAD +QS Sbjct: 3 QTVPPCELPCKEYDVARNTGAYTSSGLATASFRTSKYLLEEWFQNCYARYHQAFADRDQS 62 Query: 37 ERELQGHKSQQLAAEIQALAQPTQQDSKCRVGERLQDMHSWNSELQGEVEALAAETDLLL 96 ER Q H+SQQLA E QALAQ TQQDS VGERLQD HSW SELQ E+EALAAET+LLL Sbjct: 63 ER--QRHESQQLATETQALAQRTQQDSTRTVGERLQDTHSWKSELQREMEALAAETNLLL 120 Query: 97 AQKQRLEHALDAMEVPFSIATDNMQCNQRHQHANLVRDHVETELLKAYPPAPSQCLKNCC 156 AQKQRLE ALDA EVPFSI TDN+Q C Sbjct: 121 AQKQRLERALDATEVPFSITTDNLQ----------------------------------C 146 Query: 157 SSRKPSASNKGVCEVMETLTVQEEANPGTEGCRTRALAHKEEAELIRNIQELLKRVIVQA 216 R+ E N + T L +EAELIRNIQELLKR I+QA Sbjct: 147 RERR------------------EHPNLVRDHVETELL---KEAELIRNIQELLKRTIMQA 185 Query: 217 VSQIRLNREHMEICEMDWSDKVEAYNLDETCGRHRSQSTEPR----------SASTPETR 266 VSQIRLNREH E CEMDWSDK+EAYN+DETCGRH SQSTE + SASTPETR Sbjct: 186 VSQIRLNREHKETCEMDWSDKMEAYNIDETCGRHHSQSTEVQAHPYSTTFQESASTPETR 245 Query: 267 TKFTQDNLCRAQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGRRCEELEDARHK 326 KFTQDNLCRAQRERL SANL VLVDCILRDTSEDL LQCDAVNLAFGRRCEELEDAR+K Sbjct: 246 AKFTQDNLCRAQRERLASANLRVLVDCILRDTSEDLRLQCDAVNLAFGRRCEELEDARYK 305 Query: 327 LQHHLQKMLREITDQEHNMVALKEAIKDKEAPLHIAQTRLYLLSHRPNMELCRDAAQFRY 386 L HHL K LREITDQEHN+ ALK+AIKDKEAPLH+AQTRLYL SHRPNMELCRDAAQFR Sbjct: 306 LHHHLHKTLREITDQEHNVAALKQAIKDKEAPLHVAQTRLYLRSHRPNMELCRDAAQFR- 364 Query: 387 RHDTGQVMGRGPPSARDLCPRGLTPPSATSSSQEEAPSDKPQLTPPNTPKLVSELEELYK 446 L+SE+EEL Sbjct: 365 --------------------------------------------------LLSEVEELNM 374 Query: 447 SITALWEKLLQAEQSLHNLEDIHMSLEKDVTAMTNSLFLDRQNCMAHHTCYPTILQLAGY 506 S+TAL EKLL+AEQSL NLEDIHMSLEKD+ AMTNSLF+DRQ CMAH T YPTILQLAGY Sbjct: 375 SLTALREKLLEAEQSLRNLEDIHMSLEKDIAAMTNSLFIDRQKCMAHRTRYPTILQLAGY 434 Query: 507 Q 507 Q Sbjct: 435 Q 435 >gi|239752581 PREDICTED: MAFF interacting protein [Homo sapiens] Length = 333 Score = 417 bits (1072), Expect = e-116 Identities = 213/271 (78%), Positives = 224/271 (82%), Gaps = 30/271 (11%) Query: 16 VPPCELPCKEYDV------------------------------AFADCNQSERELQGHKS 45 +PPCELPCKEYDV AFA+CNQSE+ELQGH+S Sbjct: 1 MPPCELPCKEYDVARNTGTYMSSGLATAXLEVWFQNCYARYHQAFANCNQSEQELQGHES 60 Query: 46 QQLAAEIQALAQPTQQDSKCRVGERLQDMHSWNSELQGEVEALAAETDLLLAQKQRLEHA 105 QQLAAE QALAQ TQQDS RVGE+LQD HSW SELQ EVEALAAETDLLLAQKQRLEHA Sbjct: 61 QQLAAETQALAQGTQQDSTRRVGEQLQDTHSWKSELQREVEALAAETDLLLAQKQRLEHA 120 Query: 106 LDAMEVPFSIATDNMQCNQRHQHANLVRDHVETELLKAYPPAPSQCLKNCCSSRKPSASN 165 LDA E PFSIATDN+QC+Q HQHANL+RDHVETELLKA+PPAPSQCL NC SSRKPSA N Sbjct: 121 LDATEAPFSIATDNLQCSQGHQHANLMRDHVETELLKAHPPAPSQCLNNCFSSRKPSARN 180 Query: 166 KGVCEVMETLTVQEEANPGTEGCRTRALAHKEEAELIRNIQELLKRVIVQAVSQIRLNRE 225 KG C+VMETLTVQEEANPGTEGCRTRALAHK+EAELIRNIQELLKR IVQAVSQIRLNRE Sbjct: 181 KGPCQVMETLTVQEEANPGTEGCRTRALAHKKEAELIRNIQELLKRAIVQAVSQIRLNRE 240 Query: 226 HMEICEMDWSDKVEAYNLDETCGRHRSQSTE 256 H EICEMDWSDKVEAYNLDETCGRH SQSTE Sbjct: 241 HTEICEMDWSDKVEAYNLDETCGRHHSQSTE 271 >gi|239758055 PREDICTED: similar to tektin 4 [Homo sapiens] Length = 254 Score = 346 bits (887), Expect = 3e-95 Identities = 185/245 (75%), Positives = 197/245 (80%), Gaps = 25/245 (10%) Query: 1 MVQTDMLLPEPAPQTVPPCELPCKEYDVAFADCNQSERELQGHKSQQLAAEIQALAQPTQ 60 MVQTDMLLPEP PQT+PPCELPCKEYD AFA+CNQSERELQGH+SQQLAAE QALAQ TQ Sbjct: 1 MVQTDMLLPEPVPQTMPPCELPCKEYD-AFANCNQSERELQGHESQQLAAETQALAQGTQ 59 Query: 61 QDSKCRVGERLQDMHSWNSELQGEVEALAAETDLLLAQKQRLEHALDAMEVPFSIATDNM 120 QDS RVGE+LQD HSW SELQ EVEALAAETDLLLAQKQRLEHALDA E PFSIATDN+ Sbjct: 60 QDSTRRVGEQLQDTHSWKSELQREVEALAAETDLLLAQKQRLEHALDATEAPFSIATDNL 119 Query: 121 QCNQRHQHANLVRDHVETELLKAYPPAPSQCL---------KNC---------------C 156 QC+Q HQ+ANL+RDHVETELLK Q L +C C Sbjct: 120 QCSQGHQNANLMRDHVETELLKVPAAVGGQDLWVQRGGAPGSSCGQATWLLQAHRRPALC 179 Query: 157 SSRKPSASNKGVCEVMETLTVQEEANPGTEGCRTRALAHKEEAELIRNIQELLKRVIVQA 216 +SRKPSA NKG C+VMETLTVQEEANPGTEGCRTRALAHK+EAELIRNIQELLKR IVQA Sbjct: 180 ASRKPSARNKGPCQVMETLTVQEEANPGTEGCRTRALAHKKEAELIRNIQELLKRAIVQA 239 Query: 217 VSQIR 221 VSQIR Sbjct: 240 VSQIR 244 >gi|75677606 hypothetical protein LOC100132288 [Homo sapiens] Length = 129 Score = 214 bits (546), Expect = 1e-55 Identities = 105/110 (95%), Positives = 106/110 (96%) Query: 257 PRSASTPETRTKFTQDNLCRAQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGRR 316 PRSASTPETRTKFTQDNLC AQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFG R Sbjct: 20 PRSASTPETRTKFTQDNLCHAQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGCR 79 Query: 317 CEELEDARHKLQHHLQKMLREITDQEHNMVALKEAIKDKEAPLHIAQTRL 366 CEELEDARHKLQHHL KMLREITDQEHN+VALKEAIKDKE PLHIAQTRL Sbjct: 80 CEELEDARHKLQHHLHKMLREITDQEHNVVALKEAIKDKEEPLHIAQTRL 129 >gi|13994250 tektin 3 [Homo sapiens] Length = 490 Score = 171 bits (432), Expect = 2e-42 Identities = 140/490 (28%), Positives = 210/490 (42%), Gaps = 123/490 (25%) Query: 34 NQSERELQGHKSQQLAAEIQALAQP-------TQQDSKCRVGERLQDMHSWNSELQGEVE 86 N E H S++L + L Q TQ D+ +GER+ D+ W SE+ E++ Sbjct: 106 NYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIGFWKSEIIHELD 165 Query: 87 ALAAETDLLLAQKQRLEHALDAMEVPFSIATDNMQCNQRHQHANLVRDHVETELLKAYPP 146 + ET+ L K+RLE AL +ETE Sbjct: 166 EMIGETNALTDVKKRLERAL-----------------------------METE------- 189 Query: 147 APSQCLKNCCSSRKPSASNKGVCEVMETLTVQEEANPGTEGCRTRALAHKEEAELIRNIQ 206 AP Q + C R+ V + +E + E + I Q Sbjct: 190 APLQVARECLFHREKRMGIDLVHDEVEAQLLTE-------------------VDTILCCQ 230 Query: 207 ELLKRVIVQAVSQIRLNREHMEICEMDWSDKVEAYNLDETC----------GRHRSQSTE 256 E +K + +A++Q+ NR E D SDK AY +D+ C G R Sbjct: 231 ERMKLHLDKAIAQLAANRASQHELEKDLSDKQTAYRIDDKCHHLRNTSDGVGYFRGVERV 290 Query: 257 PRSASTPETRTKFTQDNLCRAQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGRR 316 + S PE+ KFT DN+ R+Q ER SA L ++ +L T+ ++ Q + VNL+F R Sbjct: 291 DATVSVPESWAKFTDDNILRSQSERAASAKLRDDIENLLVVTANEMWNQFNKVNLSFTNR 350 Query: 317 CEELEDARHKLQHHLQKMLREITDQEHNMVALKEAIKDKEAPLHIAQTRLYLLSHRPNME 376 E DA++K+Q HL K L+EI E + ++K+AIKDK A L +AQTRL + RPN+E Sbjct: 351 IAETADAKNKIQTHLAKTLQEIFQTEMTIESIKKAIKDKTAFLKVAQTRLDERTRRPNIE 410 Query: 377 LCRDAAQFRYRHDTGQVMGRGPPSARDLCPRGLTPPSATSSSQEEAPSDKPQLTPPNTPK 436 LCRD AQ R ++ Sbjct: 411 LCRDMAQLRLVNE----------------------------------------------- 423 Query: 437 LVSELEELYKSITALWEKLLQAEQSLHNLEDIHMSLEKDVTAMTNSLFLDRQNCMAHHTC 496 V E+++ +I L ++L AE +L +L I +LE D+ NSL++D++ CM+ Sbjct: 424 -VHEVDD---TIQTLQQRLRDAEDTLQSLVHIKATLEYDLAVKANSLYIDQEKCMSMRKS 479 Query: 497 YPTILQLAGY 506 YP L+L G+ Sbjct: 480 YPNTLRLVGF 489 Score = 32.3 bits (72), Expect = 1.0 Identities = 25/122 (20%), Positives = 49/122 (40%) Query: 262 TPETRTKFTQDNLCRAQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGRRCEELE 321 TP+ + N + R +S L V +++D + G R ++ Sbjct: 95 TPDDWYRSNLTNYQESNTSRHNSEKLRVDTSRLIQDKYQQTRKTQADTTQNLGERVNDIG 154 Query: 322 DARHKLQHHLQKMLREITDQEHNMVALKEAIKDKEAPLHIAQTRLYLLSHRPNMELCRDA 381 + ++ H L +M+ E L+ A+ + EAPL +A+ L+ R ++L D Sbjct: 155 FWKSEIIHELDEMIGETNALTDVKKRLERALMETEAPLQVARECLFHREKRMGIDLVHDE 214 Query: 382 AQ 383 + Sbjct: 215 VE 216 >gi|16753231 tektin 1 [Homo sapiens] Length = 418 Score = 167 bits (424), Expect = 2e-41 Identities = 139/502 (27%), Positives = 210/502 (41%), Gaps = 118/502 (23%) Query: 8 LPEPAPQTVPPCELPCKEYDVAFADCNQSERELQGHKSQQLAAEIQALAQPTQQDSKCRV 67 L +P P+ +P + AD +S E +SQ+L EI+ + +Q D ++ Sbjct: 4 LLQPPPKFLPSEWHIANKNQYHRADAQRSRSERLVAESQRLVDEIEKTTRKSQSDVNKKL 63 Query: 68 GERLQDMHSWNSELQGEVEALAAETDLLLAQKQRLEHALDAMEVPFSIATDNMQCNQRHQ 127 +RL+++ W EL ++E L TD LL K RLE AL Sbjct: 64 EQRLEEVQFWKKELDDKLEQLVNVTDDLLIYKIRLEKAL--------------------- 102 Query: 128 HANLVRDHVETELLKAYPPAPSQCLKNCCSSRKPSASNKGVCEVMETLTVQEEANPGTEG 187 E LK P + C + R+ V + +E ++E Sbjct: 103 -----------ETLKE----PLHITETCLAYREKRIGIDLVHDTVEHELIKE-------- 139 Query: 188 CRTRALAHKEEAELIRNIQELLKRVIVQAVSQIRLNREHMEICEMDWSDKVEAYNLDETC 247 AE+I+ I LL R + +A QIR+NR E D DK A +D+ C Sbjct: 140 -----------AEIIQGIMALLTRTLEEASEQIRMNRSAKYNLEKDLKDKFVALTIDDIC 188 Query: 248 GRHRSQST-----------EPRSASTPETRTKFTQDNLCRAQRERLDSANLWVLVDCILR 296 + S EP S S E F+ N+ +A ++R +S L LVD IL Sbjct: 189 FSLNNNSPNIRYSENAVRIEPNSVSL-EDWLDFSSTNVEKADKQRNNSLMLKALVDRILS 247 Query: 297 DTSEDLGLQCDAVNLAFGRRCEELEDARHKLQHHLQKMLREITDQEHNMVALKEAIKDKE 356 T+ DL QCD V+ AF ++ +DAR KL HL K++ EI QE N+ AL++AI D+E Sbjct: 248 QTANDLRKQCDVVDTAFKNGLKDTKDARDKLADHLAKVMEEIASQEKNITALEKAILDQE 307 Query: 357 APLHIAQTRLYLLSHRPNMELCRDAAQFRYRHDTGQVMGRGPPSARDLCPRGLTPPSATS 416 P +A TRL +HRPN+ELCRD AQ+R Sbjct: 308 GPAKVAHTRLETRTHRPNVELCRDVAQYR------------------------------- 336 Query: 417 SSQEEAPSDKPQLTPPNTPKLVSELEELYKSITALWEKLLQAEQSLHNLEDIHMSLEKDV 476 L+ E++E+ ++ L E L QA+ L L ++L++++ Sbjct: 337 --------------------LMKEVQEITHNVARLKETLAQAQAELKGLHRRQLALQEEI 376 Query: 477 TAMTNSLFLDRQNCMAHHTCYP 498 N++++D CM P Sbjct: 377 QVKENTIYIDEVLCMQMRKSIP 398 >gi|21389569 tektin 5 [Homo sapiens] Length = 485 Score = 125 bits (315), Expect = 7e-29 Identities = 116/457 (25%), Positives = 181/457 (39%), Gaps = 117/457 (25%) Query: 61 QDSKCR-VGERLQDMHSWNSELQGEVEALAAETDLLLAQKQRLEHALDAMEVPFSIATDN 119 Q+ CR +G+RL D+ W SEL E++ L E L K+RLE A + Sbjct: 134 QEGTCRNLGQRLSDIGFWKSELSYELDRLLTENQNLETVKRRLE-----------CAANE 182 Query: 120 MQCNQRHQHANLVRDHVETELLKAYPPAPSQCLKNCCSSRKPSASNKGVCEVMETLTVQE 179 + C P Q C R+ V + +E ++E Sbjct: 183 VNC-------------------------PLQVALECLYHREKRIGIDLVHDNVEKNLIRE 217 Query: 180 EANPGTEGCRTRALAHKEEAELIRNIQELLKRVIVQAVSQIRLNREHMEICEMDWSDKVE 239 +L++ QE ++++ + Q+R NR+ + E D DK Sbjct: 218 -------------------VDLLKCCQEQMRKLAQRIDIQMRDNRDAQHVLERDLEDKSS 258 Query: 240 AYNLDETCGRHRSQST----------EPRSASTPETRTKFTQDNLCRAQRERLDSANLWV 289 A +DE C R+ S + S PET KF+ DN+ +Q R +S L Sbjct: 259 AQCIDEKCFNLRNTSDCISFFHGMEKIDGTISVPETWAKFSNDNIKHSQNMRANSIQLRE 318 Query: 290 LVDCILRDTSEDLGLQCDAVNLAFGRRCEELEDARHKLQHHLQKMLREITDQEHNMVALK 349 + + S+ + Q NLAF R E+ D ++KLQ L K L+EI E+ ++ L+ Sbjct: 319 EAEHLFETLSDQMWRQFTDTNLAFNARISEVTDVKNKLQTQLAKTLQEIFQAENTIMLLE 378 Query: 350 EAIKDKEAPLHIAQTRLYLLSHRPNMELCRDAAQFRYRHDTGQVMGRGPPSARDLCPRGL 409 +I KE PL +AQTRL + RPNMELCRD Sbjct: 379 RSIMAKEGPLKVAQTRLECRTRRPNMELCRDI---------------------------- 410 Query: 410 TPPSATSSSQEEAPSDKPQLTPPNTPKLVSELEELYKSITALWEKLLQAEQSLHNLEDIH 469 PQL KLV+E+ + ++ L +L + + +L L Sbjct: 411 -----------------PQL------KLVNEVFTIDDTLQTLKLRLRETQDTLQLLVMTK 447 Query: 470 MSLEKDVTAMTNSLFLDRQNCMAHHTCYPTILQLAGY 506 LE ++ N+L +D++ CM +P +L G+ Sbjct: 448 CRLEHELAIKANTLCIDKEKCMGMRKTFPCTPRLVGH 484 >gi|16507950 tektin 2 [Homo sapiens] Length = 430 Score = 82.4 bits (202), Expect = 9e-16 Identities = 106/470 (22%), Positives = 178/470 (37%), Gaps = 124/470 (26%) Query: 39 ELQGHKSQQLAAEIQALAQPT-------QQDSKCRVGERLQDMHSWNSELQGEVEALAAE 91 +LQ S Q+ E + L T + D++ R+ ER+ ++ W L + L AE Sbjct: 29 QLQRDASHQIRQEARVLRNETNNQTIWDEHDNRTRLVERIDTVNRWKEMLDKCLTDLDAE 88 Query: 92 TDLLLAQKQRLEHALDAMEVPFSIATDNMQCNQRHQHANLVRDHVETELLKAYPPAPSQC 151 D L K+ E Q Q NL P Sbjct: 89 IDALTQMKESAE--------------------QNLQAKNL----------------PLDV 112 Query: 152 LKNCCSSRKPSASNKGVCEVMETLTVQEEANPGTEGCRTRALAHKEEAELIRNIQELLKR 211 C + R+ S + + V + V++E + +E E+I ++ L++ Sbjct: 113 AIECLTLRE---SRRDIDVVKDP--VEDELH--------------KEVEVIEATKKALQQ 153 Query: 212 VIVQAVSQIRLNREHMEICEMDWSDKVEAYNLDETCGRHRSQSTE----------PRSAS 261 + QA Q+ L +E + D K+E +D C +S P ++ Sbjct: 154 KVSQAFEQLCLLQEVQQQLNSDHRGKMETLEIDRGCLSLNLRSPNISLKVDPTRVPDGST 213 Query: 262 TPETRTKFTQDNLCRAQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGRRCEELE 321 T + F++ N RA+ E + L + +T+ +L Q A AF +R E+E Sbjct: 214 TLQQWDDFSRFNKDRAEAEMKAATELREATALTIAETNNELEAQRVATEFAFRKRLREME 273 Query: 322 DARHKLQHHLQKMLREITDQEHNMVALKEAIKDKEAPLHIAQTRLYLLSHRPNMELCRDA 381 +L+ + L EI + + ++ L+E ++ K L ++ TRL ++RPN+ELCRD Sbjct: 274 KVYSELKWQEKNTLEEIAELQEDIRHLEEDLRTKLLSLKLSHTRLEARTYRPNVELCRDQ 333 Query: 382 AQFRYRHDTGQVMGRGPPSARDLCPRGLTPPSATSSSQEEAPSDKPQLTPPNTPKLVSEL 441 AQ+ GLT E+ Sbjct: 334 AQY-----------------------GLT----------------------------DEV 342 Query: 442 EELYKSITALWEKLLQAEQSLHNLEDIHMSLEKDVTAMTNSLFLDRQNCM 491 +L +I AL +KL QA+ +L L L+ D+ NS+ LD + CM Sbjct: 343 HQLEATIAALKQKLAQAQDALDALCKHLARLQADIACKANSMLLDTK-CM 391 >gi|169209613 PREDICTED: hypothetical protein LOC100128785 [Homo sapiens] Length = 639 Score = 67.8 bits (164), Expect = 2e-11 Identities = 49/124 (39%), Positives = 67/124 (54%), Gaps = 16/124 (12%) Query: 101 RLEHALDAMEVPFSIATDNMQCNQRHQHANLVRDHVETELLKAYPPAPSQ---CLKNCCS 157 +L HA D M VPFSIAT+N+Q +++ H LV D+VETELLK P Q L+ C Sbjct: 303 QLCHASDTMTVPFSIATNNLQYHEQCWHPYLVGDYVETELLKVLRPRGGQDCPLLRTLCP 362 Query: 158 SRKPSASNKGVCEVMETLTVQEEANPGTEGCRTRALAHKEEAELIRNIQELLKRVIVQAV 217 R + L+V++ G + R L +EAELI +I ELL+R VQA Sbjct: 363 FR-----------IQHDLSVKQPRRVPGSGAQGRLLI--QEAELIGSIPELLERPTVQAG 409 Query: 218 SQIR 221 ++ R Sbjct: 410 NRSR 413 Score = 37.7 bits (86), Expect = 0.025 Identities = 20/40 (50%), Positives = 27/40 (67%) Query: 435 PKLVSELEELYKSITALWEKLLQAEQSLHNLEDIHMSLEK 474 P+L +E+E L+ S+ L EKLL+ EQSL NLE + EK Sbjct: 445 PRLGNEVEGLHASLVVLREKLLEVEQSLGNLEYVQEPGEK 484 >gi|169210642 PREDICTED: hypothetical protein LOC100128785 [Homo sapiens] Length = 639 Score = 67.8 bits (164), Expect = 2e-11 Identities = 49/124 (39%), Positives = 67/124 (54%), Gaps = 16/124 (12%) Query: 101 RLEHALDAMEVPFSIATDNMQCNQRHQHANLVRDHVETELLKAYPPAPSQ---CLKNCCS 157 +L HA D M VPFSIAT+N+Q +++ H LV D+VETELLK P Q L+ C Sbjct: 303 QLCHASDTMTVPFSIATNNLQYHEQCWHPYLVGDYVETELLKVLRPRGGQDCPLLRTLCP 362 Query: 158 SRKPSASNKGVCEVMETLTVQEEANPGTEGCRTRALAHKEEAELIRNIQELLKRVIVQAV 217 R + L+V++ G + R L +EAELI +I ELL+R VQA Sbjct: 363 FR-----------IQHDLSVKQPRRVPGSGAQGRLLI--QEAELIGSIPELLERPTVQAG 409 Query: 218 SQIR 221 ++ R Sbjct: 410 NRSR 413 Score = 37.7 bits (86), Expect = 0.025 Identities = 20/40 (50%), Positives = 27/40 (67%) Query: 435 PKLVSELEELYKSITALWEKLLQAEQSLHNLEDIHMSLEK 474 P+L +E+E L+ S+ L EKLL+ EQSL NLE + EK Sbjct: 445 PRLGNEVEGLHASLVVLREKLLEVEQSLGNLEYVQEPGEK 484 >gi|169210176 PREDICTED: hypothetical protein LOC100128785 [Homo sapiens] Length = 639 Score = 67.8 bits (164), Expect = 2e-11 Identities = 49/124 (39%), Positives = 67/124 (54%), Gaps = 16/124 (12%) Query: 101 RLEHALDAMEVPFSIATDNMQCNQRHQHANLVRDHVETELLKAYPPAPSQ---CLKNCCS 157 +L HA D M VPFSIAT+N+Q +++ H LV D+VETELLK P Q L+ C Sbjct: 303 QLCHASDTMTVPFSIATNNLQYHEQCWHPYLVGDYVETELLKVLRPRGGQDCPLLRTLCP 362 Query: 158 SRKPSASNKGVCEVMETLTVQEEANPGTEGCRTRALAHKEEAELIRNIQELLKRVIVQAV 217 R + L+V++ G + R L +EAELI +I ELL+R VQA Sbjct: 363 FR-----------IQHDLSVKQPRRVPGSGAQGRLLI--QEAELIGSIPELLERPTVQAG 409 Query: 218 SQIR 221 ++ R Sbjct: 410 NRSR 413 Score = 37.7 bits (86), Expect = 0.025 Identities = 20/40 (50%), Positives = 27/40 (67%) Query: 435 PKLVSELEELYKSITALWEKLLQAEQSLHNLEDIHMSLEK 474 P+L +E+E L+ S+ L EKLL+ EQSL NLE + EK Sbjct: 445 PRLGNEVEGLHASLVVLREKLLEVEQSLGNLEYVQEPGEK 484 >gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] Length = 1960 Score = 45.1 bits (105), Expect = 2e-04 Identities = 89/371 (23%), Positives = 149/371 (40%), Gaps = 53/371 (14%) Query: 37 ERELQGHKSQQLAAEIQALAQPTQQDSKCRVGERLQDMHSWNSELQGEVEALAAETDLLL 96 E EL + +QLAAE + T Q +LQ+ +EL E E L A L Sbjct: 851 EEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRAR---LT 907 Query: 97 AQKQRLE---HALDAMEVPFSIATDNMQCNQRHQHANL--VRDHVETE--------LLKA 143 A+KQ LE H L+A ++Q ++ N+ + + +E E L K Sbjct: 908 AKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKV 967 Query: 144 YPPAPSQCL---------KNCCSSRKPSASNKGVCEVMETLTVQEEANPGTEGCRTRALA 194 A + L +NC +++ + E LT +EE + L Sbjct: 968 TTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKS-----LAKLK 1022 Query: 195 HKEEAELIRNIQELLKRVIVQAVSQIRLNREHMEICEMDWSDKV-EAYNLDETCGRHRSQ 253 +K EA +I +++E L+R Q ++ R +E D SD++ E ++ Sbjct: 1023 NKHEA-MITDLEERLRREEKQR-QELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAK 1080 Query: 254 STEPRSASTPETRTKFTQDNLCRAQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAF 313 E A+ + Q N+ + L+S + + EDL + + N A Sbjct: 1081 KEEELQAALARVEEEAAQKNMALKKIRELESQ---------ISELQEDLESERASRNKAE 1131 Query: 314 GRR---CEELEDARHKLQHHL-----QKMLREITDQEHNMVALKEAIKDKEAPLHIAQTR 365 ++ EELE + +L+ L Q+ LR +QE N+ LK+ + ++EA H AQ + Sbjct: 1132 KQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNI--LKKTL-EEEAKTHEAQIQ 1188 Query: 366 LYLLSHRPNME 376 H +E Sbjct: 1189 EMRQKHSQAVE 1199 Score = 42.4 bits (98), Expect = 0.001 Identities = 66/322 (20%), Positives = 130/322 (40%), Gaps = 49/322 (15%) Query: 44 KSQQLAAEIQALAQPTQQDSKCRVGERLQDMHSWNSELQGEVEALAAETDLLLAQKQRLE 103 K ++L A + + + Q + ++++++ S SELQ ++E+ A + QK+ L Sbjct: 1081 KEEELQAALARVEEEAAQKNMAL--KKIRELESQISELQEDLESERASRNKAEKQKRDLG 1138 Query: 104 HALDAMEVPFSIATDNMQCNQ-----RHQHANLVRDHVETELLKAYPPAPSQCLKNCCSS 158 L+A++ D+ Q R Q N+++ +E E K+ Sbjct: 1139 EELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKH---- 1194 Query: 159 RKPSASNKGVCEVMETLTVQEEANPGTEGCRTRALAHKEEAELIRNIQELL--------K 210 ++ V E+ E L + E + + E EL ++ LL K Sbjct: 1195 ------SQAVEELAEQLEQTKRVKANLE--KAKQTLENERGELANEVKVLLQGKGDSEHK 1246 Query: 211 RVIVQAVSQ---IRLN---REHMEICEMDWSDKVEAYNLDETCGRHRSQSTE-PRSASTP 263 R V+A Q ++ N R E+ + +VE N+ + S+S++ + S Sbjct: 1247 RKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSAL 1306 Query: 264 ETRTKFTQDNLCRAQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGRRCEELEDA 323 E++ + TQ+ L R++L + V+ D N +F + EE E+A Sbjct: 1307 ESQLQDTQELLQEENRQKLSLSTKLKQVE--------------DEKN-SFREQLEEEEEA 1351 Query: 324 RHKLQHHLQKMLREITDQEHNM 345 +H L+ + + ++ D + M Sbjct: 1352 KHNLEKQIATLHAQVADMKKKM 1373 Score = 32.3 bits (72), Expect = 1.0 Identities = 65/299 (21%), Positives = 128/299 (42%), Gaps = 44/299 (14%) Query: 84 EVEALAAETDLLLAQKQRL--EHALDAMEVPFS-IATDNMQCNQRHQHANLVRDHVETEL 140 E E +A E +L+ ++++L E+ L ME S + + +Q ++ Q ETEL Sbjct: 844 EEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQ--------AETEL 895 Query: 141 LKAYPPAPSQCLKNCCSSRKPSASNKGVCEVMETLTVQEEANPGTEGCRTRALAHKEEAE 200 A ++ L+ +++K +C +E +EE E C+ E+ + Sbjct: 896 C-----AEAEELRARLTAKKQELEE--ICHDLEARVEEEE-----ERCQH---LQAEKKK 940 Query: 201 LIRNIQELLKRVIVQAVSQIRLNREHMEI-CEMDWSDKVEAYNLDETCGRHRSQST-EPR 258 + +NIQEL +++ + ++ +L E + ++ ++ + D+ C + + E R Sbjct: 941 MQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDR 1000 Query: 259 SASTPETRTKFTQDNLCRAQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGRRCE 318 A +FT NL + + A L + ++ D E L + ++ + Sbjct: 1001 IA-------EFTT-NLTEEEEKSKSLAKLKNKHEAMITDLEERLRRE--------EKQRQ 1044 Query: 319 ELEDARHKLQHHLQKMLREITDQEHNMVALKEAIKDKEAPLHIAQTRLYLLSHRPNMEL 377 ELE R KL+ + +I + + + LK + KE L A R+ + + NM L Sbjct: 1045 ELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMAL 1103 >gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapiens] Length = 1478 Score = 42.7 bits (99), Expect = 8e-04 Identities = 84/393 (21%), Positives = 157/393 (39%), Gaps = 64/393 (16%) Query: 25 EYDVAFADCNQSERELQGHKSQQLAAEIQALAQPTQQDSKCRVGERLQDMHSWNSELQGE 84 + D + + +E L+ HK+ +Q L + + ++ V E LQ SE +G Sbjct: 805 DQDKVQSQLSMAEAVLREHKTL-----VQQLKEQNEALNRAHVQELLQC-----SEREGA 854 Query: 85 VEALAAETDLLLAQKQRLEHALDAMEVPFSIATDNMQCNQRHQHANLVRDHVETELLKAY 144 ++ A+ + Q+ E L A++ S A +C+ + A L ++ +L +A Sbjct: 855 LQEERAD------EAQQREEELRALQEELSQA----KCSS--EEAQLEHAELQEQLHRAN 902 Query: 145 PPAPSQCLKNCCSS-RKPSASNKGVCEVMETLTVQEEANPGTEGCRTRALAHKEEAELIR 203 ++ C + K C V E +E A+ EG + ++E E Sbjct: 903 TDTAELGIQVCALTVEKERVEEALACAVQELQDAKEAASREREGLERQVAGLQQEKE--- 959 Query: 204 NIQELLKRV-------------IVQAVSQIRLNRE--HMEICE---------MDWSDKVE 239 ++QE LK + QA + + +E H E+ MD+ +++ Sbjct: 960 SLQEKLKAAKAAAGSLPGLQAQLAQAEQRAQSLQEAAHQELNTLKFQLSAEIMDYQSRLK 1019 Query: 240 AYNLDETC----GRHRSQSTEPRSASTPETRTKFTQDNLCRAQRERLDSANLWVLVDCIL 295 N E C G+ Q + ++A + K TQ ++ ++ S +L +L Sbjct: 1020 --NAGEECKSLRGQLEEQGRQLQAAEEAVEKLKATQADM--GEKLSCTSNHLAECQAAML 1075 Query: 296 RDTSEDLGLQCDAVNLAFGRRCEELEDARHKLQHHLQKMLREITDQEHNMVALKEAIKDK 355 R E L+ D R +ELE A K+Q + K+ +E+T++E N + + D Sbjct: 1076 RKDKEGAALRED-----LERTQKELEKATTKIQEYYNKLCQEVTNRERNDQKMLADLDDL 1130 Query: 356 EAPLHIAQTRLY-LLSHRPNMELCRDAAQFRYR 387 + RL LL + + DA +F+ + Sbjct: 1131 NRTKKYLEERLIELLRDKDALWQKSDALEFQQK 1163 Score = 33.1 bits (74), Expect = 0.61 Identities = 86/417 (20%), Positives = 164/417 (39%), Gaps = 82/417 (19%) Query: 17 PPCELPCK-EYDVAFADCNQSERELQGHKSQQLAAEIQALAQPTQQDSKCRVGERLQDMH 75 P ELP E + A N S +E G + E + L + D+K + G + +++ Sbjct: 560 PGPELPVAGEKNEALVPVNSSLQEAWGKPEE----EQRGLQEAQLDDTKVQEGSQEEELR 615 Query: 76 SWNSELQGEVEALAAETDLLLAQKQRLEHALDAME-----VPFSIAT-DNMQCNQRH--- 126 N EL+ E++ + LL + Q L+ A++ + S+A+ + Q + RH Sbjct: 616 QANRELEKELQNVVGRNQLLEGKLQALQADYQALQQRESAIQGSLASLEAEQASIRHLGD 675 Query: 127 -QHANLVRDHVETELLKAYPPAP------------------SQCLKNCCSSRKPSASNKG 167 A+L+ E +KA QC + + + + + Sbjct: 676 QMEASLLAVRKAKEAMKAQMAEKEAILQSKEGECQQLREEVEQCQQLAEARHRELRALES 735 Query: 168 VC----EVMETLTV---QEEANPGTEGCRTRALAHK---EEAEL---IRNIQELLKRVI- 213 C +++E LT Q+ P T+ R LA + +A+L +Q L +V+ Sbjct: 736 QCQQQTQLIEVLTAEKGQQGVGPPTDN-EARELAAQLALSQAQLEVHQGEVQRLQAQVVD 794 Query: 214 VQAVSQIRLN----------------REHMEICEM--DWSDKVEAYNLDE--TCGRHRSQ 253 +QA + L+ REH + + + ++ + ++ E C Sbjct: 795 LQAKMRAALDDQDKVQSQLSMAEAVLREHKTLVQQLKEQNEALNRAHVQELLQCSEREGA 854 Query: 254 STEPRS--ASTPETRTKFTQDNL----CRAQRERLDSANLWVLVDCILRDTSEDLGLQCD 307 E R+ A E + Q+ L C ++ +L+ A L + DT+E LG+Q Sbjct: 855 LQEERADEAQQREEELRALQEELSQAKCSSEEAQLEHAELQEQLHRANTDTAE-LGIQVC 913 Query: 308 AVNL-------AFGRRCEELEDARHKLQHHLQKMLREITDQEHNMVALKEAIKDKEA 357 A+ + A +EL+DA+ + + R++ + +L+E +K +A Sbjct: 914 ALTVEKERVEEALACAVQELQDAKEAASREREGLERQVAGLQQEKESLQEKLKAAKA 970 >gi|46592991 GRIP1 associated protein 1 isoform 1 [Homo sapiens] Length = 841 Score = 42.0 bits (97), Expect = 0.001 Identities = 115/516 (22%), Positives = 190/516 (36%), Gaps = 114/516 (22%) Query: 35 QSERELQGHKSQQLAAEIQALAQPTQQDSKCRVGERL---------QDMHSWNS-ELQGE 84 +++ + Q ++Q+L E++A Q + R GERL QD S S + Q + Sbjct: 268 EADHKAQLARTQKLQQELEAANQSLAELRDQRQGERLEHAAALRALQDQVSIQSADAQEQ 327 Query: 85 VEALAAETDLLLAQKQRLEHALDAM--------EVPFSIATDNMQCNQRHQHANLVRDHV 136 VE L AE + L LE A E +A + Q ++ +D + Sbjct: 328 VEGLLAENNALRTSLAALEQIQTAKTQELNMLREQTTGLAAELQQQQAEYEDLMGQKDDL 387 Query: 137 ETEL-------------LKAYPPAPSQCLKNCCSSRKPSASNKGVCEVMETLTVQEEANP 183 ++L L+ Q + +RK + K + + + T+QE++ Sbjct: 388 NSQLQESLRANSRLLEQLQEIGQEKEQLTQELQEARKSAEKRKAMLDELAMETLQEKSQ- 446 Query: 184 GTEGCRTRALAHKEEAELIRNIQELLKRVI-VQAVSQIRLNREHMEICEMDWSDKVEAYN 242 HKEE +R E K V+ V+A R RE E+ E DK Sbjct: 447 -----------HKEELGAVRLRHE--KEVLGVRA----RYERELRELHE----DKKRQE- 484 Query: 243 LDETCGRHRSQSTEPRSASTPETRTKFTQDNLCRAQRERLDSANLWVLVDCILRDTSEDL 302 +E G+ R + R T + + Q AQ +D A W + L++ E L Sbjct: 485 -EELRGQIREEKARTRELETLQQTVEELQ-----AQVHSMDGAKGWF--ERRLKEAEESL 536 Query: 303 GLQCDAVNLAFGRRC------------EELEDARHKLQH-------HLQ---KMLREITD 340 Q A ++C EEL+D R +L+ HL+ + +E+ D Sbjct: 537 QQQQQEQEEAL-KQCREQHAAELKGKEEELQDVRDQLEQAQEERDCHLKTISSLKQEVKD 595 Query: 341 QEHNMVALKE----AIKDKEAPLHIAQTRLYLLSHRPN------------MELCRDAAQF 384 L++ A+KD + LH+ + R L R EL Sbjct: 596 TVDGQRILEKKGSAALKDLKRQLHLERKRADKLQERLQDILTNSKSRSGLEELVLSEMNS 655 Query: 385 RYRHDTGQVMGRGPPSARDLCPR---GLTPPSATSSSQEEAPSDKPQLTPPNTPKLV-SE 440 R TG S R++ P + SSS PQ PP +L E Sbjct: 656 PSRTQTGDSSSISSFSYREILREKESSAVPARSLSSS--------PQAQPPRPAELSDEE 707 Query: 441 LEELYKSITALWEKLLQAEQSLHNLEDIHMSLEKDV 476 + EL++ + ++ E+ + +LE S+ +D+ Sbjct: 708 VAELFQRLAETQQEKWMLEEKVKHLEVSSASMAEDL 743 >gi|122937396 coiled-coil domain containing 150 [Homo sapiens] Length = 1101 Score = 40.4 bits (93), Expect = 0.004 Identities = 72/367 (19%), Positives = 146/367 (39%), Gaps = 58/367 (15%) Query: 27 DVAFADCNQSERELQGHKSQQLAAEIQALAQPTQ-----QDSKCRVGERLQDMHSWNSEL 81 D A A + +Q K+Q A + + Q QD++ R + + + S + L Sbjct: 397 DAAHASITNELQTVQNEKTQLQAHLDHLILEHNQCIQKAQDAEKRTAVQKELLESTIARL 456 Query: 82 QGEVEALAAETDLLLAQKQR------------------LEHALDAMEVPFSIATDNMQCN 123 +GE+EA E LL +K+R LE L +V + T N+Q Sbjct: 457 RGELEASMQEKKSLLEEKERFQREVNKTEKEIVQERCNLEKELAKNKVDINTLTHNLQ-T 515 Query: 124 QRHQHANLVRDHVETELLKA---YPPAPSQCLKNCCSSRKPSASNKGVCEVMETLTVQEE 180 ++ +L EL + Y Q ++ S+ A G ++ + ++E+ Sbjct: 516 LEEENKHLADQMASLELQQVTSDYHGLAQQKVEKITESKNKLAYENGKLQI-KVKQLEEQ 574 Query: 181 ANPGTEGCRTRALAHKEEAELIRNIQELLKRVIVQAVSQIRLNREHMEICEMDWSDKVEA 240 T+ + + +R + + L+ QA S++ R H++ + + E Sbjct: 575 VQSFTD--------TSLQNDHLRKMNKYLQTKYAQANSELSAKRVHLQQAD---AHLKEV 623 Query: 241 YNLDETCGRHRSQSTEPRSASTPETRTKFTQDNLCRAQRE--------------RLDSAN 286 ++ E S++ + R+A+ E++ K +D RE + D+ Sbjct: 624 KSILERSKEELSRTVKCRNAALKESQ-KLKEDLEAVEDRENKKVGNFQRQLAEAKEDNCK 682 Query: 287 LWVLVDCILRDTSEDLGLQCDAVNLAFGRRCEE---LEDARHKLQHHLQKMLREITDQEH 343 + ++++ +L S+ G + V + GRR E L+ R Q +QK+ E+ + Sbjct: 683 VTIMLENVLASHSKMQG-ALEKVQIELGRRDSEIAGLKKERDLNQQRVQKLEAEVDQWQA 741 Query: 344 NMVALKE 350 M+ +++ Sbjct: 742 RMLVMED 748 >gi|4504063 golgin 97 [Homo sapiens] Length = 767 Score = 38.9 bits (89), Expect = 0.011 Identities = 92/463 (19%), Positives = 169/463 (36%), Gaps = 56/463 (12%) Query: 31 ADCNQSERELQGHKSQQLAAEIQALAQPTQQDSKCRVGERLQDMHSWNSELQGEVEALAA 90 +D +Q ELQ H S +A T +SK E+ + ELQ ++ L+ Sbjct: 224 SDLSQKLEELQRHYSTLEEQRDHVIASKTGAESKITALEQKEQ------ELQALIQQLSI 277 Query: 91 ETDLLLAQKQRLEHALDAMEVPFSIATDNMQCNQRHQHANLVRDHVETELLKAYPPAPS- 149 + + A+ Q E + ++ + ++ N + +HV+ ELLK A Sbjct: 278 DLQKVTAETQEKEDVITHLQEKVASLEKRLEQNLSGE------EHVQ-ELLKEKTLAEQN 330 Query: 150 ------QCLKNCCSSRKP-SASNKGVCEVMETLTVQEEANPGTEGCRTRALAHKEEAELI 202 Q L S K + V E+ +TL EE ++G A + + + + Sbjct: 331 LEDTRQQLLAARSSQAKAINTLETRVRELEQTLQASEEQLQQSKGI---VAAQETQIQEL 387 Query: 203 RNIQELLKRVIVQAVSQIRLNREHMEICEMDWSDKVEAYNLDETCGRHRSQSTEPRSAST 262 + V QA++ + E + E D+T + E +A+ Sbjct: 388 AAANQESSHVQQQALALEQQFLERTQALEAQIVALERTRAADQTTAEQGMRQLEQENAAL 447 Query: 263 PETRTKFTQDNLCRAQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGRRCEELED 322 E R ++ + Q + + L+ E+ Q + V++A + EE+ Sbjct: 448 KECRNEYERS----LQNHQFE-----------LKKLKEEWS-QREIVSVAMAQALEEVRK 491 Query: 323 ARHKLQHHLQKMLREITDQEHNMVALKEAIKDKE---APLHIAQTRLYLLSHRPNMEL-- 377 R + Q + I ++E N+ E + KE L L H+ EL Sbjct: 492 QREEFQQQAANLTAIIDEKEQNLREKTEVLLQKEQEILQLERGHNSALLQIHQLQAELEA 551 Query: 378 -----CRDAAQFRYRHDTGQVMGRGPPSARDLCPRGLTPPSATSSSQEEAPSDKPQL-TP 431 +AA + D ++ RGP A L + TS + ++ P Sbjct: 552 LRTLKAEEAAVVAEQEDLLRL--RGPLQAEAL---SVNESHVTSRAMQDPVFQLPTAGRT 606 Query: 432 PNTPKLVSELEELYKSITALWEKLLQAEQSLHNLEDIHMSLEK 474 PN +L +L K L ++LL+ +++ ++ + L K Sbjct: 607 PNGEVGAMDLTQLQKEKQDLEQQLLEKNKTIKQMQQRMLELRK 649 >gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo sapiens] Length = 1983 Score = 38.9 bits (89), Expect = 0.011 Identities = 85/356 (23%), Positives = 138/356 (38%), Gaps = 53/356 (14%) Query: 31 ADCNQSERELQGHKSQQLAAEIQALAQPTQQDSKCRVGERL-------QDMHSWNSELQG 83 A+ + REL+ + + A + AL + Q + +GE++ Q + SEL+ Sbjct: 1218 AELGRLRRELE-EAALRHEATVAALRRK-QAEGAAELGEQVDSLQRVRQKLEKEKSELRM 1275 Query: 84 EVEALAAETDLLLAQKQRLEHALDAMEVPFSIATDNMQCNQRH-QHANLVRDHVETE--- 139 EV+ LAA + L K E E S A ++ QR A+ R ++TE Sbjct: 1276 EVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGE 1335 Query: 140 ---LLKAYPPAPSQCLKNCCSSRKPSASNKGVCEVMETLTVQEEANPGTEGCRTRAL-AH 195 LL+ +CL + S K A+ + +E L Q E + A+ A Sbjct: 1336 LSRLLE-----EKECLISQLSRGKALAA-----QSLEELRRQLEEESKAKSALAHAVQAL 1385 Query: 196 KEEAELIRNIQELLKRVIVQAVSQIRLNREHMEICEMDWSDKVEAYNLDETCGRHRSQST 255 + + +L+R E + QA Q L++ + E+ + W K EA + T + Sbjct: 1386 RHDCDLLREQHE--EEAEAQAELQRLLSKANAEVAQ--WRSKYEADAIQRT-----EELE 1436 Query: 256 EPRSASTPETRTKFTQDNLCRAQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGR 315 E + + A+ L+ A L L+ SED+ L+ + Sbjct: 1437 EAKKKLALRLQEAEEGVEAANAKCSSLEKAKL------RLQTESEDVTLELE-------- 1482 Query: 316 RCEELEDARHKLQHHLQKMLREITDQEHNMVALKEAIKDKEAPLHIAQTRLYLLSH 371 R A K Q HL++ L E QE M EA + + L T L+ L H Sbjct: 1483 RATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGL---GTELFRLRH 1535 >gi|81295809 pericentrin [Homo sapiens] Length = 3336 Score = 38.1 bits (87), Expect = 0.019 Identities = 84/371 (22%), Positives = 143/371 (38%), Gaps = 43/371 (11%) Query: 19 CELPCKEYDVAFADCNQSERELQ-----GHKSQQLAAEIQALAQPTQQDSKCRVGERLQD 73 CE K ++ + C + LQ K +L A +Q L + + + Sbjct: 2614 CESRQKSEQLSRSLCEVQQEVLQLRSMLSSKENELKAALQELESEQGKGRALQSQLEEEQ 2673 Query: 74 MHSWNSELQGE--VEALAAETDLLLAQKQRLEHALDAMEVPFSIATDNMQCNQRHQHAN- 130 + E Q +E L A + AQ RL AL + A DN+Q R +H+ Sbjct: 2674 LRHLQRESQSAKALEELRASLETQRAQSSRLCVALKHEQT----AKDNLQKELRIEHSRC 2729 Query: 131 ---LVRDHVE-TELLKAYPPAPSQCLKNCCSSRKPSASNKGVCEVMETLTVQEEANPGTE 186 L ++ + +EL K S+ L+ + R + + + + V ++ T+ Sbjct: 2730 EALLAQERSQLSELQKDLAAEKSRTLELSEALRHERLLTEQLSQRTQEACVHQD----TQ 2785 Query: 187 GCRTRALAHKEEAELIRNIQELLKRVIVQAV-SQIRLNREHMEICEMDWSDKVEAYNLDE 245 KEE + ++Q +L++V QA+ SQ +L E + CE +K + L Sbjct: 2786 AHHALLQKLKEEKSRVVDLQAMLEKVQQQALHSQQQLEAEAQKHCEALRREKEVSATLKS 2845 Query: 246 TCGRHRSQSTEPRSASTPETRTKFTQDNLCRAQRERLDSANLWVLVDCILRDTSEDLGLQ 305 T +Q E R C +RER A L ++ E G + Sbjct: 2846 TVEALHTQKRELR----------------CSLEREREKPAWLQAELEQSHPRLKEQEGRK 2889 Query: 306 CDAVNLAFGRRCEELEDARHKLQHHLQKMLREITDQE----HNMVALKEAIKDKEAPLHI 361 A A R+ + K Q +K LRE+ Q H + L++ ++D E+ + Sbjct: 2890 A-ARRSAEARQSPAAAEQWRKWQRDKEK-LRELELQRQRDLHKIKQLQQTVRDLESKDEV 2947 Query: 362 AQTRLYLLSHR 372 +RL+L S R Sbjct: 2948 PGSRLHLGSAR 2958 Score = 30.0 bits (66), Expect = 5.2 Identities = 32/111 (28%), Positives = 48/111 (43%), Gaps = 19/111 (17%) Query: 25 EYDVAFADCNQSERELQGHKSQQLAAEIQALAQPTQQDSKCRVGERLQDMH----SWNSE 80 E + F D NQ+ER L+ +S QA + ++D + G L+D+ E Sbjct: 390 ELEKIFQDKNQAERALRNLESHH-----QAAIEKLREDLQSEHGRCLEDLEFKFKESEKE 444 Query: 81 LQGEVEALAAETDLLLAQKQ----RLEHALDAMEVPFSIATDNMQCNQRHQ 127 Q E+E L A + L AQ Q RL LD S T + ++ H+ Sbjct: 445 KQLELENLQASYEDLKAQSQEEIRRLWSQLD------SARTSRQELSELHE 489 >gi|169211436 PREDICTED: hypothetical protein [Homo sapiens] Length = 280 Score = 37.7 bits (86), Expect = 0.025 Identities = 18/40 (45%), Positives = 22/40 (55%) Query: 399 PSARDLCPRGLTPPSATSSSQEEAPSDKPQLTPPNTPKLV 438 PS+R + R TP SS+ PS P LTP NTP L+ Sbjct: 184 PSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSNTPTLI 223 Score = 31.2 bits (69), Expect = 2.3 Identities = 16/39 (41%), Positives = 19/39 (48%) Query: 399 PSARDLCPRGLTPPSATSSSQEEAPSDKPQLTPPNTPKL 437 PS+ R TP SS+ PS P LTP +TP L Sbjct: 136 PSSTPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTL 174 >gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] Length = 2017 Score = 37.7 bits (86), Expect = 0.025 Identities = 72/347 (20%), Positives = 138/347 (39%), Gaps = 40/347 (11%) Query: 35 QSERELQGHKSQQLA---AEIQALAQPTQQDSKCRVGERLQDMHSWNSELQGEVEALAAE 91 ++ ++L G +QL+ +E +AL + Q R+ ++ + + Q EV+ L + Sbjct: 543 EASQDLLGTLRKQLSDSESERRALEEQLQ-----RLRDKTDGAMQAHEDAQREVQRLRSA 597 Query: 92 TDLLLAQKQRLEHALD-AMEVPFSIATDNMQCNQRHQHANLVRDHVETELLKAYPPAPSQ 150 +LL +K L H+L A + + + + + RD +E E A ++ Sbjct: 598 NELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDG-AR 656 Query: 151 CLKNCCSSRKPSASNKGVCEVM--ETLTVQEEANPGTEGCRTRALAHKEEAELIRNIQEL 208 + S + +G V+ E + V+E + T R + E+AE+ + + Sbjct: 657 VRRELERSHRQLEQLEGKRSVLAKELVEVREALSRAT---LQRDMLQAEKAEVAEALTKA 713 Query: 209 LKRVIVQAVSQIRLNREHMEICEMDWSDKVEAYN-------LDETCGRHRSQSTEPRSAS 261 + +S +L E + D K+ A N LD R +Q E +SA Sbjct: 714 EAGRVELELSMTKLRAEEASL--QDSLSKLSALNESLAQDKLD--LNRLVAQLEEEKSAL 769 Query: 262 TPETRTKFTQDNLCRAQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGRRCEELE 321 R + + R ++ERL+ L + R E + A ++ L Sbjct: 770 QGRQRQAEQEATVAREEQERLEELR---LEQEVARQGLEGSLRVAEQAQEALEQQLPTLR 826 Query: 322 DARHKLQHHLQKMLREITDQEHNM-----------VALKEAIKDKEA 357 R +LQ L ++ R+++ +E + AL+ A ++KEA Sbjct: 827 HERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEA 873 Score = 36.2 bits (82), Expect = 0.072 Identities = 74/362 (20%), Positives = 135/362 (37%), Gaps = 39/362 (10%) Query: 35 QSERELQGHKSQQLAAEIQALAQPTQQDSKCRVGERLQDMHSWNSELQGEVEALAAETD- 93 Q E+E + + A++Q+ Q Q+ E L + + EL E+ AL E D Sbjct: 999 QREKEAAWRELEAERAQLQSQLQREQE-------ELLARLEAEKEELSEEIAALQQERDE 1051 Query: 94 -LLLAQKQRLEHALDAMEVPFSIATDNMQCNQRHQHANLV----RDHVETELLKAYPPAP 148 LLLA+ ++ + AL E + ++ + RH A + R + + + + Sbjct: 1052 GLLLAESEK-QQALSLKESEKTALSEKLM-GTRHSLATISLEMERQKRDAQSRQEQDRST 1109 Query: 149 SQCLKNCCSSRKPSASNKGVCEVMETLTVQEEANP---GTEGCRTRALAHKEEAELIRNI 205 L + + E +QE+A + C A + + L+ + Sbjct: 1110 VNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDA 1169 Query: 206 QELLKRVIVQAVSQIRLNREHMEICEMDWSDKVEAYNLDETCGRHRSQSTEPRSASTPET 265 ++ L+R +++A ++R ++E E+ + EA L + G ++ E S E Sbjct: 1170 RDGLRRELLEAQRKLRESQEGREV------QRQEAGELRRSLG-EGAKEREALRRSNEEL 1222 Query: 266 RTKFTQDNLCRAQRERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGRRCEELEDARH 325 R+ + ++R L AN D + L L + A G+ EL Sbjct: 1223 RSAVKK---AESERISLKLAN---------EDKEQKLAL-LEEARTAVGKEAGELRTGLQ 1269 Query: 326 KLQHHLQKMLREITDQEHNMVALKEAIKDKEAPLHIAQTRLYLLSHRPNMELCRDAAQFR 385 +++ + RE+ + M L L Q RL L R E R+ R Sbjct: 1270 EVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRL-ALGERAEKESRRETLGLR 1328 Query: 386 YR 387 R Sbjct: 1329 QR 1330 >gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 306 Score = 37.0 bits (84), Expect = 0.042 Identities = 18/39 (46%), Positives = 22/39 (56%) Query: 399 PSARDLCPRGLTPPSATSSSQEEAPSDKPQLTPPNTPKL 437 PS+R + R TP SS+ PS+ P LTP NTP L Sbjct: 234 PSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTL 272 Score = 34.7 bits (78), Expect = 0.21 Identities = 17/39 (43%), Positives = 21/39 (53%) Query: 399 PSARDLCPRGLTPPSATSSSQEEAPSDKPQLTPPNTPKL 437 PS++ + R TP SS PS+ P LTP NTP L Sbjct: 28 PSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTL 66 Score = 34.7 bits (78), Expect = 0.21 Identities = 17/39 (43%), Positives = 21/39 (53%) Query: 399 PSARDLCPRGLTPPSATSSSQEEAPSDKPQLTPPNTPKL 437 PS+R + R TP SS+ PS P LTP +TP L Sbjct: 162 PSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTL 200 Score = 30.4 bits (67), Expect = 4.0 Identities = 19/45 (42%), Positives = 20/45 (44%), Gaps = 5/45 (11%) Query: 398 PPSARDLCP-----RGLTPPSATSSSQEEAPSDKPQLTPPNTPKL 437 P S L P R TP SS PS+ P LTP NTP L Sbjct: 76 PSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTL 120 Score = 30.0 bits (66), Expect = 5.2 Identities = 16/39 (41%), Positives = 19/39 (48%) Query: 399 PSARDLCPRGLTPPSATSSSQEEAPSDKPQLTPPNTPKL 437 PS+R + R TP SS PS P LTP + P L Sbjct: 202 PSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPIL 240 Score = 29.6 bits (65), Expect = 6.8 Identities = 16/39 (41%), Positives = 19/39 (48%) Query: 399 PSARDLCPRGLTPPSATSSSQEEAPSDKPQLTPPNTPKL 437 PS+R + R TP SS S P LTP +TP L Sbjct: 146 PSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTL 184 >gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 306 Score = 37.0 bits (84), Expect = 0.042 Identities = 18/39 (46%), Positives = 22/39 (56%) Query: 399 PSARDLCPRGLTPPSATSSSQEEAPSDKPQLTPPNTPKL 437 PS+R + R TP SS+ PS+ P LTP NTP L Sbjct: 234 PSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTL 272 Score = 34.7 bits (78), Expect = 0.21 Identities = 17/39 (43%), Positives = 21/39 (53%) Query: 399 PSARDLCPRGLTPPSATSSSQEEAPSDKPQLTPPNTPKL 437 PS++ + R TP SS PS+ P LTP NTP L Sbjct: 28 PSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTL 66 Score = 34.7 bits (78), Expect = 0.21 Identities = 17/39 (43%), Positives = 21/39 (53%) Query: 399 PSARDLCPRGLTPPSATSSSQEEAPSDKPQLTPPNTPKL 437 PS+R + R TP SS+ PS P LTP +TP L Sbjct: 162 PSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTL 200 Score = 30.4 bits (67), Expect = 4.0 Identities = 19/45 (42%), Positives = 20/45 (44%), Gaps = 5/45 (11%) Query: 398 PPSARDLCP-----RGLTPPSATSSSQEEAPSDKPQLTPPNTPKL 437 P S L P R TP SS PS+ P LTP NTP L Sbjct: 76 PSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTL 120 Score = 30.0 bits (66), Expect = 5.2 Identities = 16/39 (41%), Positives = 19/39 (48%) Query: 399 PSARDLCPRGLTPPSATSSSQEEAPSDKPQLTPPNTPKL 437 PS+R + R TP SS PS P LTP + P L Sbjct: 202 PSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPSSRPIL 240 Score = 29.6 bits (65), Expect = 6.8 Identities = 16/39 (41%), Positives = 19/39 (48%) Query: 399 PSARDLCPRGLTPPSATSSSQEEAPSDKPQLTPPNTPKL 437 PS+R + R TP SS S P LTP +TP L Sbjct: 146 PSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTL 184 >gi|115527097 CDC42-binding protein kinase beta [Homo sapiens] Length = 1711 Score = 36.6 bits (83), Expect = 0.055 Identities = 38/160 (23%), Positives = 62/160 (38%), Gaps = 12/160 (7%) Query: 69 ERLQDMHSWNSELQGEVEALAAETDLLLAQKQRLEHALDAMEVPFSIATDNMQC-NQRHQ 127 + L+D H E L L AQKQ++ L E +AT + Q + Sbjct: 561 KELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRDKEEEMEVATQKVDAMRQEMR 620 Query: 128 HANLVRDHVETELLKAYPPAPSQCLKNCCSSRKPSASNKGVCEVMETLTVQEEANPGTEG 187 A +R +E +L A A + RK ++ C+ ME+ + G G Sbjct: 621 RAEKLRKELEAQLDDAVAEASKE--------RKLREHSENFCKQMESELEALKVKQGGRG 672 Query: 188 CRTRALAHKEEAELIRNIQELLKRVIVQAVSQIRLNREHM 227 L H++E I++ EL K+V+ +R H+ Sbjct: 673 AGA-TLEHQQEISKIKS--ELEKKVLFYEEELVRREASHV 709 >gi|21735548 centrosomal protein 2 [Homo sapiens] Length = 2442 Score = 35.8 bits (81), Expect = 0.094 Identities = 90/396 (22%), Positives = 156/396 (39%), Gaps = 49/396 (12%) Query: 31 ADCNQSERELQGHKSQQLAAEIQALAQPTQQDSKCRVGERLQDMHSWNSELQGEVEALAA 90 A C ++ LQ + Q E +AL Q Q+ GER + +LQGEV++L+ Sbjct: 410 AGCQEAVNLLQ-QQHDQWEEEGKALRQRLQK----LTGER-DTLAGQTVDLQGEVDSLSK 463 Query: 91 ETDLLLAQKQRLEHALDAME----------VPFSIATDNMQCNQRHQHANL---VRDHVE 137 E +LL ++ L L+ +E V + D+ Q + Q L VR+ Sbjct: 464 ERELLQKAREELRQQLEVLEQEAWRLRRVNVELQLQGDSAQGQKEEQQEELHLAVRERER 523 Query: 138 -TELLKAYPPAPSQCLKNCCSSRKPSASNKGVCEVMETLTVQEEANPGTEGCRTRALAHK 196 E+L S+ L + R+ S+ E++ QE+ TE A A + Sbjct: 524 LQEMLMGLEAKQSESLSELITLREALESSHLEGELLR----QEQ----TEVTAALARAEQ 575 Query: 197 EEAELIRNIQELLKRVIVQAVSQIRLNREHMEICEMDWSDKVEAYNLDETCGRHRSQSTE 256 AEL + L V + ++L+ + + + L+E +QS Sbjct: 576 SIAELSSSENTLKTEVADLRAAAVKLSALNEALALDKVGLNQQLLQLEE-----ENQSVC 630 Query: 257 PRSASTPETRTKFTQDNLCRAQRERLDSANLWVLVDCILRDTSE-DLGLQCDAVNLAFGR 315 R + + R Q +L A++ R ++ L+ E LQ D ++ Sbjct: 631 SRMEAAEQARNAL-QVDLAEAEKRREALWEKNTHLEAQLQKAEEAGAELQADLRDIQ--- 686 Query: 316 RCEELEDARHKL--QHHLQKMLREITDQEHNMVALKEAIKDKEAPLHIAQTRLYLLSHRP 373 EE E+ + KL H Q+ +Q H +EA + +E Q + L+ + Sbjct: 687 --EEKEEIQKKLSESRHQQEAATTQLEQLH-----QEAKRQEEVLARAVQEKEALVREKA 739 Query: 374 NMELCRDAAQFRYRHDTGQVMGRGPPSARDLCPRGL 409 +E+ A + R R D + + +G SA++L L Sbjct: 740 ALEVRLQAVE-RDRQDLAEQL-QGLSSAKELLESSL 773 >gi|4502443 dystonin isoform 1e precursor [Homo sapiens] Length = 2649 Score = 35.8 bits (81), Expect = 0.094 Identities = 58/321 (18%), Positives = 134/321 (41%), Gaps = 20/321 (6%) Query: 51 EIQALAQPTQQDSKCR--VGERLQDMHSWNSELQGEVEALAAETDLLLAQKQRLEHALDA 108 +IQ L + ++ ++C + ++++++ N+E + ++ + AE++ ++ +KQ ++ +A Sbjct: 1554 KIQRLNEELEKSNECAEMLKQKVEELTRQNNETKLMMQRIQAESENIVLEKQTIQQRCEA 1613 Query: 109 MEVPFSIATDNMQCNQRHQHANLVRDHVETELLKAYPP--APSQCL----KNCCSSRKPS 162 +++ D ++ H H + +K A SQ L K C + Sbjct: 1614 LKIQADGFKDQLRSTNEHLHKQTKTEQDFQRKIKCLEEDLAKSQNLVSEFKQKCDQQNII 1673 Query: 163 ASN--KGVCEVMETLTVQEEANPGTEGCRTRALAHKEEAELIRNIQELLKRVIVQAVSQI 220 N K V + L +E G + L + EL ++++ + ++ + + Sbjct: 1674 IQNTKKEVRNLNAELNASKEEK--RRGEQKVQLQQAQVQELNNRLKKVQDELHLKTIEEQ 1731 Query: 221 RLNREHMEICEMDWSDKVEAYNLDETCGRHRSQS--TEPRSASTPETRTKFTQDNLCRAQ 278 +R+ + E K A + + TE + Q+N + Sbjct: 1732 MTHRKMVLFQEESGKFKQSAEEFRKKMEKLMESKVITENDISGIRLDFVSLQQENSRAQE 1791 Query: 279 RERLDSANLWVLVDCILRDTSEDLGLQCDAVNLAFGRRCEELED----ARHKLQHHLQKM 334 +L N+ L + L+ E + Q + ++C++LED + ++++ QKM Sbjct: 1792 NAKLCETNIKEL-ERQLQQYREQM-QQGQHMEANHYQKCQKLEDELIAQKREVENLKQKM 1849 Query: 335 LREITDQEHNMVALKEAIKDK 355 ++I + EH +V L+ I+ K Sbjct: 1850 DQQIKEHEHQLVLLQCEIQKK 1870 >gi|4759082 serum deprivation response protein [Homo sapiens] Length = 425 Score = 35.4 bits (80), Expect = 0.12 Identities = 32/125 (25%), Positives = 53/125 (42%), Gaps = 12/125 (9%) Query: 380 DAAQFRYRHDTGQVMGRGPPSARDLCPRGLTPPSATSSSQEEAPSDKPQLTPPNTPKLVS 439 DAAQ G M + PS+ P PS + EEA D Q+ N +++ Sbjct: 4 DAAQAEKFQHPGSDMRQEKPSSPSPMPSSTPSPSLNLGNTEEAIRDNSQV---NAVTVLT 60 Query: 440 ELEELYKSITALWEKLLQAEQSLHNLEDIHMSLEKDVTAM---------TNSLFLDRQNC 490 L++L + A+ E + EQ +LE ++ D+T + T S L++ Sbjct: 61 LLDKLVNMLDAVQENQHKMEQRQISLEGSVKGIQNDLTKLSKYQASTSNTVSKLLEKSRK 120 Query: 491 MAHHT 495 ++ HT Sbjct: 121 VSAHT 125 >gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin repeats isoform 2 [Homo sapiens] Length = 1403 Score = 34.7 bits (78), Expect = 0.21 Identities = 83/467 (17%), Positives = 172/467 (36%), Gaps = 56/467 (11%) Query: 24 KEYDVAFADCNQSERELQGHKS---QQLAAEIQALAQPTQQDSKCRVGERLQDMHSWNSE 80 +E++ + ++ Q +REL+ K+ Q + E + + +G+++ ++ N Sbjct: 642 REHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQT 701 Query: 81 LQGEVEALAAETDLLLAQKQRLEHALDAMEVPFSIATDNMQCNQRHQHANLVRDHVETEL 140 LQ E+E + + LL Q L + VP ++ D + H ++ D + +L Sbjct: 702 LQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSED-----MKKSHDAII-DDLNRKL 755 Query: 141 LKAYPPAPSQCLKNCCSSRKPSASNKGVCEVMETLTVQEEANPGTEGCRTRALAHKEEAE 200 L + L+ + + +K V +ET+ V E + KE Sbjct: 756 LDVTQKYTEKKLEMEKLLLENDSLSKDVSR-LETVFVPPEKH------------EKEIIA 802 Query: 201 LIRNIQELLKRVIVQAVSQIRLNREHMEICEMDWSDKVEAYNLDETCGRHRSQSTEPRSA 260 L NI EL K++ E + C D +K+ A + T + S + Sbjct: 803 LKSNIVELKKQL-----------SELKKKCGED-QEKIHALTSENT-NLKKMMSNQYVPV 849 Query: 261 STPETRTKFTQDNLCRAQRERLDSANLWVLVD---CILRDTSEDLGLQCDAVNLAFGRRC 317 T E D L + RE LD + ++ ++D +E L + N + Sbjct: 850 KTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLE--NTQNQIKA 907 Query: 318 EELEDARHKLQ-HHLQKMLREITDQEHNMVALKEAIKDKEAPLHIAQTRLYLLSHRPNME 376 E + A H+ + L + +R++ D ++A +++ LH + + + ++ Sbjct: 908 EYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAE-----IKAQKKELD 962 Query: 377 LCRDAAQFRYRHDTGQVMGRGPPSARDLCPRGLTPPSATSSSQEEAPSDKPQLTPPNTPK 436 ++ + +Y P + + C R Q + K ++ K Sbjct: 963 TIQECIKVKY----------APIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKK 1012 Query: 437 LVSELEELYKSITALWEKLLQAEQSLHNLEDIHMSLEKDVTAMTNSL 483 E ++L K I L + L + ++ +L + + L Sbjct: 1013 NKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQL 1059 >gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin repeats isoform 1 [Homo sapiens] Length = 1416 Score = 34.7 bits (78), Expect = 0.21 Identities = 83/467 (17%), Positives = 172/467 (36%), Gaps = 56/467 (11%) Query: 24 KEYDVAFADCNQSERELQGHKS---QQLAAEIQALAQPTQQDSKCRVGERLQDMHSWNSE 80 +E++ + ++ Q +REL+ K+ Q + E + + +G+++ ++ N Sbjct: 655 REHEKSLSEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQT 714 Query: 81 LQGEVEALAAETDLLLAQKQRLEHALDAMEVPFSIATDNMQCNQRHQHANLVRDHVETEL 140 LQ E+E + + LL Q L + VP ++ D + H ++ D + +L Sbjct: 715 LQKEIEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSED-----MKKSHDAII-DDLNRKL 768 Query: 141 LKAYPPAPSQCLKNCCSSRKPSASNKGVCEVMETLTVQEEANPGTEGCRTRALAHKEEAE 200 L + L+ + + +K V +ET+ V E + KE Sbjct: 769 LDVTQKYTEKKLEMEKLLLENDSLSKDVSR-LETVFVPPEKH------------EKEIIA 815 Query: 201 LIRNIQELLKRVIVQAVSQIRLNREHMEICEMDWSDKVEAYNLDETCGRHRSQSTEPRSA 260 L NI EL K++ E + C D +K+ A + T + S + Sbjct: 816 LKSNIVELKKQL-----------SELKKKCGED-QEKIHALTSENT-NLKKMMSNQYVPV 862 Query: 261 STPETRTKFTQDNLCRAQRERLDSANLWVLVD---CILRDTSEDLGLQCDAVNLAFGRRC 317 T E D L + RE LD + ++ ++D +E L + N + Sbjct: 863 KTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLE--NTQNQIKA 920 Query: 318 EELEDARHKLQ-HHLQKMLREITDQEHNMVALKEAIKDKEAPLHIAQTRLYLLSHRPNME 376 E + A H+ + L + +R++ D ++A +++ LH + + + ++ Sbjct: 921 EYISLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAE-----IKAQKKELD 975 Query: 377 LCRDAAQFRYRHDTGQVMGRGPPSARDLCPRGLTPPSATSSSQEEAPSDKPQLTPPNTPK 436 ++ + +Y P + + C R Q + K ++ K Sbjct: 976 TIQECIKVKY----------APIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKK 1025 Query: 437 LVSELEELYKSITALWEKLLQAEQSLHNLEDIHMSLEKDVTAMTNSL 483 E ++L K I L + L + ++ +L + + L Sbjct: 1026 NKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKTDELNKQL 1072 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.316 0.129 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,966,372 Number of Sequences: 37866 Number of extensions: 976677 Number of successful extensions: 6023 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 39 Number of HSP's successfully gapped in prelim test: 132 Number of HSP's that attempted gapping in prelim test: 5565 Number of HSP's gapped (non-prelim): 629 length of query: 507 length of database: 18,247,518 effective HSP length: 107 effective length of query: 400 effective length of database: 14,195,856 effective search space: 5678342400 effective search space used: 5678342400 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.