Guide to the Human Genome
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Search of human proteins with 239745503

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239745503 PREDICTED: hypothetical protein XP_002343506 [Homo
sapiens]
         (501 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239745503 PREDICTED: hypothetical protein XP_002343506 [Homo ...  1019   0.0  
gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens]           981   0.0  
gi|189011568 adenomatous polyposis coli [Homo sapiens]                 33   0.79 
gi|189011566 adenomatous polyposis coli [Homo sapiens]                 33   0.79 
gi|53759122 adenomatous polyposis coli [Homo sapiens]                  33   0.79 
gi|121114304 fms-related tyrosine kinase 3 [Homo sapiens]              32   1.3  
gi|113865883 WD repeat domain 38 [Homo sapiens]                        31   2.3  
gi|6912666 sialin [Homo sapiens]                                       30   3.9  
gi|40217799 hypothetical protein LOC79864 isoform 1 [Homo sapiens]     30   3.9  
gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens]                 30   5.1  
gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens]                 30   5.1  
gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens]                  30   5.1  
gi|6679074 nucleoporin like 2 [Homo sapiens]                           30   5.1  
gi|219842266 usherin isoform B [Homo sapiens]                          29   8.7  

>gi|239745503 PREDICTED: hypothetical protein XP_002343506 [Homo
           sapiens]
          Length = 501

 Score = 1019 bits (2636), Expect = 0.0
 Identities = 501/501 (100%), Positives = 501/501 (100%)

Query: 1   MTWALEVAVLMKKSETYAPLFCLPSFHKFCKGLLANTLVEDVNICLQACSSLPALSSSLP 60
           MTWALEVAVLMKKSETYAPLFCLPSFHKFCKGLLANTLVEDVNICLQACSSLPALSSSLP
Sbjct: 1   MTWALEVAVLMKKSETYAPLFCLPSFHKFCKGLLANTLVEDVNICLQACSSLPALSSSLP 60

Query: 61  DDLLQRCVDVCRVQLVHCGTRIRQAFGKLLKSIPLDVILSNNNHTEIQEISLALRSHMSK 120
           DDLLQRCVDVCRVQLVHCGTRIRQAFGKLLKSIPLDVILSNNNHTEIQEISLALRSHMSK
Sbjct: 61  DDLLQRCVDVCRVQLVHCGTRIRQAFGKLLKSIPLDVILSNNNHTEIQEISLALRSHMSK 120

Query: 121 APSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKHDQSTIPRNLLKTDAI 180
           APSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKHDQSTIPRNLLKTDAI
Sbjct: 121 APSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKHDQSTIPRNLLKTDAI 180

Query: 181 LWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADSDE 240
           LWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADSDE
Sbjct: 181 LWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADSDE 240

Query: 241 GHGNNQLRLVLLLQYLEYLEKLMYNAYEGCANALTSPPKVIRTFFYTNHQTCQDWLTRIR 300
           GHGNNQLRLVLLLQYLEYLEKLMYNAYEGCANALTSPPKVIRTFFYTNHQTCQDWLTRIR
Sbjct: 241 GHGNNQLRLVLLLQYLEYLEKLMYNAYEGCANALTSPPKVIRTFFYTNHQTCQDWLTRIR 300

Query: 301 LSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEALCELHCPEAIQG 360
           LSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEALCELHCPEAIQG
Sbjct: 301 LSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEALCELHCPEAIQG 360

Query: 361 IAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMIGVHCCISSFDKSVLTLAN 420
           IAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMIGVHCCISSFDKSVLTLAN
Sbjct: 361 IAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMIGVHCCISSFDKSVLTLAN 420

Query: 421 AGCNSASPKHCLNGESRKTVLSKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIH 480
           AGCNSASPKHCLNGESRKTVLSKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIH
Sbjct: 421 AGCNSASPKHCLNGESRKTVLSKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIH 480

Query: 481 DLKKSTSSTSLNLKADFNYIK 501
           DLKKSTSSTSLNLKADFNYIK
Sbjct: 481 DLKKSTSSTSLNLKADFNYIK 501


>gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens]
          Length = 3661

 Score =  981 bits (2537), Expect = 0.0
 Identities = 487/501 (97%), Positives = 490/501 (97%)

Query: 1    MTWALEVAVLMKKSETYAPLFCLPSFHKFCKGLLANTLVEDVNICLQACSSLPALSSSLP 60
            MTWALE AVLMKKSETYAPLF LPSFHKFCKGLLANTLVEDVNICLQACSSL ALSSSLP
Sbjct: 732  MTWALEAAVLMKKSETYAPLFSLPSFHKFCKGLLANTLVEDVNICLQACSSLHALSSSLP 791

Query: 61   DDLLQRCVDVCRVQLVHCGTRIRQAFGKLLKSIPLDVILSNNNHTEIQEISLALRSHMSK 120
            DDLLQRCVDVCRVQLVH GTRIRQAFGKLLKSIPLDV+LSNNNHTEIQEISLALRSHMSK
Sbjct: 792  DDLLQRCVDVCRVQLVHSGTRIRQAFGKLLKSIPLDVVLSNNNHTEIQEISLALRSHMSK 851

Query: 121  APSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKHDQSTIPRNLLKTDAI 180
            APSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDK DQSTIPRNLLKTDA+
Sbjct: 852  APSNTFHPQDFSDVISFILYGNSHRTGKDNWLERLFYSCQRLDKRDQSTIPRNLLKTDAV 911

Query: 181  LWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADSDE 240
            LWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTAD+DE
Sbjct: 912  LWQWAIWEAAQFTVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADNDE 971

Query: 241  GHGNNQLRLVLLLQYLEYLEKLMYNAYEGCANALTSPPKVIRTFFYTNHQTCQDWLTRIR 300
            GHGNNQLRLVLLLQYLE LEKLMYNAYEGCANALTSPPKVIRTFFYTN QTCQDWLTRIR
Sbjct: 972  GHGNNQLRLVLLLQYLENLEKLMYNAYEGCANALTSPPKVIRTFFYTNRQTCQDWLTRIR 1031

Query: 301  LSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEALCELHCPEAIQG 360
            LSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEALCELHCPEAIQG
Sbjct: 1032 LSIMRVGLLAGQPAVTVRHGFDLLTEMKTTSLSQGNELEVTIMMVVEALCELHCPEAIQG 1091

Query: 361  IAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMIGVHCCISSFDKSVLTLAN 420
            IAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAM GV CCISSFDKSVLTLAN
Sbjct: 1092 IAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQEHLCAMTGVDCCISSFDKSVLTLAN 1151

Query: 421  AGCNSASPKHCLNGESRKTVLSKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIH 480
            AG NSASPKH LNGESRKTVLSKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIH
Sbjct: 1152 AGRNSASPKHSLNGESRKTVLSKPTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIH 1211

Query: 481  DLKKSTSSTSLNLKADFNYIK 501
            DLKKSTSSTSLNLKADFNYIK
Sbjct: 1212 DLKKSTSSTSLNLKADFNYIK 1232


>gi|189011568 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 32.7 bits (73), Expect = 0.79
 Identities = 15/30 (50%), Positives = 18/30 (60%)

Query: 39   VEDVNICLQACSSLPALSSSLPDDLLQRCV 68
            VED  +C    SSL +LS    DDLLQ C+
Sbjct: 2014 VEDTPVCFSRNSSLSSLSIDSEDDLLQECI 2043


>gi|189011566 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 32.7 bits (73), Expect = 0.79
 Identities = 15/30 (50%), Positives = 18/30 (60%)

Query: 39   VEDVNICLQACSSLPALSSSLPDDLLQRCV 68
            VED  +C    SSL +LS    DDLLQ C+
Sbjct: 2014 VEDTPVCFSRNSSLSSLSIDSEDDLLQECI 2043


>gi|53759122 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 32.7 bits (73), Expect = 0.79
 Identities = 15/30 (50%), Positives = 18/30 (60%)

Query: 39   VEDVNICLQACSSLPALSSSLPDDLLQRCV 68
            VED  +C    SSL +LS    DDLLQ C+
Sbjct: 2014 VEDTPVCFSRNSSLSSLSIDSEDDLLQECI 2043


>gi|121114304 fms-related tyrosine kinase 3 [Homo sapiens]
          Length = 993

 Score = 32.0 bits (71), Expect = 1.3
 Identities = 39/156 (25%), Positives = 65/156 (41%), Gaps = 24/156 (15%)

Query: 193 TVLSKLRTPLGRAQDTFQTIEGIIRSLAAHTLNPDQDVSQWTTADSDEGHGNNQLRLVLL 252
           T+L  LR P  R  +    +  I  S+        + + +W   DS +G    +    ++
Sbjct: 163 TLLYTLRRPYFRKMENQDALVCISESVP-------EPIVEWVLCDS-QGESCKEESPAVV 214

Query: 253 LQYLEYLEKLMYNAYEGCA-NALTSPPKVIRTFFYTNHQTCQDWLTRIRLSIMRVGLLAG 311
            +  + L +L       CA N L    +  R F    +QT Q  L ++ L +       G
Sbjct: 215 KKEEKVLHELFGTDIRCCARNELGR--ECTRLFTIDLNQTPQTTLPQLFLKV-------G 265

Query: 312 QP------AVTVRHGFDLLTEMKTTSLSQGNELEVT 341
           +P      AV V HGF L  E++  +L +GN  E++
Sbjct: 266 EPLWIRCKAVHVNHGFGLTWELENKALEEGNYFEMS 301


>gi|113865883 WD repeat domain 38 [Homo sapiens]
          Length = 314

 Score = 31.2 bits (69), Expect = 2.3
 Identities = 18/58 (31%), Positives = 26/58 (44%), Gaps = 1/58 (1%)

Query: 444 PTDSSPEVINYLGNKACECYISIADWAAVQEWQNAIHDLKKSTSSTSLNLKADFNYIK 501
           P  S   +  +  N +C CY S +   A   W   IH  K +TSS  + LK    ++K
Sbjct: 181 PAVSHQALEGHSANISCLCY-SASGLLASGSWDKTIHIWKPTTSSLLIQLKGHVTWVK 237


>gi|6912666 sialin [Homo sapiens]
          Length = 495

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 12/29 (41%), Positives = 18/29 (62%)

Query: 207 DTFQTIEGIIRSLAAHTLNPDQDVSQWTT 235
           +TF TI G++  + A +L PD  V +W T
Sbjct: 430 NTFATIPGMVGPVIAKSLTPDNTVGEWQT 458


>gi|40217799 hypothetical protein LOC79864 isoform 1 [Homo sapiens]
          Length = 778

 Score = 30.4 bits (67), Expect = 3.9
 Identities = 25/73 (34%), Positives = 35/73 (47%), Gaps = 10/73 (13%)

Query: 94  PLDVILSNNNHTEIQEISLALRSHMSKAPSNTFHP--QDFSDVISFILYG-------NSH 144
           P  +++ + ++ ++Q  S ALRSH  K  SNTF P  Q F  V+S    G       N  
Sbjct: 411 PESIVIMHASNNDVQA-SRALRSHNLKETSNTFAPPKQAFDKVLSKNSTGCDSGLNVNKE 469

Query: 145 RTGKDNWLERLFY 157
           R  KD   +R  Y
Sbjct: 470 RGHKDQEEKRFSY 482


>gi|213972621 ATPase type 13A2 isoform 3 [Homo sapiens]
          Length = 1158

 Score = 30.0 bits (66), Expect = 5.1
 Identities = 14/35 (40%), Positives = 20/35 (57%)

Query: 51  SLPALSSSLPDDLLQRCVDVCRVQLVHCGTRIRQA 85
           S+P L ++LP+ L   C +  R   + CGT I QA
Sbjct: 344 SIPVLKTALPEGLGPYCAETHRRHTLFCGTLILQA 378


>gi|213972619 ATPase type 13A2 isoform 2 [Homo sapiens]
          Length = 1175

 Score = 30.0 bits (66), Expect = 5.1
 Identities = 14/35 (40%), Positives = 20/35 (57%)

Query: 51  SLPALSSSLPDDLLQRCVDVCRVQLVHCGTRIRQA 85
           S+P L ++LP+ L   C +  R   + CGT I QA
Sbjct: 344 SIPVLKTALPEGLGPYCAETHRRHTLFCGTLILQA 378


>gi|13435129 ATPase type 13A2 isoform 1 [Homo sapiens]
          Length = 1180

 Score = 30.0 bits (66), Expect = 5.1
 Identities = 14/35 (40%), Positives = 20/35 (57%)

Query: 51  SLPALSSSLPDDLLQRCVDVCRVQLVHCGTRIRQA 85
           S+P L ++LP+ L   C +  R   + CGT I QA
Sbjct: 349 SIPVLKTALPEGLGPYCAETHRRHTLFCGTLILQA 383


>gi|6679074 nucleoporin like 2 [Homo sapiens]
          Length = 423

 Score = 30.0 bits (66), Expect = 5.1
 Identities = 18/65 (27%), Positives = 34/65 (52%), Gaps = 6/65 (9%)

Query: 437 RKTVLSKPTDSSPEVI-----NYLGNKACECYISIADWAAVQEWQNAIHDLKKSTSSTSL 491
           +K  +S  TD SPE +     N+L +   + Y++      + +W+N +++LK    ST +
Sbjct: 143 KKPNISGFTDISPEELRLEYHNFLTSNNLQSYLNSVQ-RLINQWRNRVNELKSLNISTKV 201

Query: 492 NLKAD 496
            L +D
Sbjct: 202 ALLSD 206


>gi|219842266 usherin isoform B [Homo sapiens]
          Length = 5202

 Score = 29.3 bits (64), Expect = 8.7
 Identities = 21/98 (21%), Positives = 37/98 (37%), Gaps = 9/98 (9%)

Query: 355  PEAIQGIAVWSSSIVGKNLLWINSVAQQAEGRFEKASVEYQ-------EHLCAMIGVHCC 407
            P  +    +W+ S    N+ W     Q   G+  K  V Y        + LC ++     
Sbjct: 4356 PSEVSPPDLWAVSATQMNVCWSPPTVQN--GKITKYLVRYDNKESLAGQGLCLLVSHLQP 4413

Query: 408  ISSFDKSVLTLANAGCNSASPKHCLNGESRKTVLSKPT 445
             S ++ S++   N GC ++  K     E+    +  PT
Sbjct: 4414 YSQYNFSLVACTNGGCTASVSKSAWTMEALPENMDSPT 4451


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.132    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,726,970
Number of Sequences: 37866
Number of extensions: 782631
Number of successful extensions: 1691
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1674
Number of HSP's gapped (non-prelim): 22
length of query: 501
length of database: 18,247,518
effective HSP length: 106
effective length of query: 395
effective length of database: 14,233,722
effective search space: 5622320190
effective search space used: 5622320190
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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