Guide to the Human Genome
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Search of human proteins with 239743857

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239743857 PREDICTED: hypothetical protein XP_002342979 [Homo
sapiens]
         (163 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239743857 PREDICTED: hypothetical protein XP_002342979 [Homo ...   336   6e-93
gi|239755066 PREDICTED: similar to tight junction protein 2 (zon...   333   3e-92
gi|239749588 PREDICTED: hypothetical protein XP_002347097 [Homo ...   333   3e-92
gi|40254988 LSM domain containing 1 [Homo sapiens]                     29   1.6  
gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens]              29   2.1  
gi|21717832 sperm equatorial segment protein 1 [Homo sapiens]          29   2.1  
gi|46410931 attractin-like 1 [Homo sapiens]                            28   2.7  
gi|54607051 glucocerebrosidase precursor [Homo sapiens]                28   4.6  
gi|54607049 glucocerebrosidase precursor [Homo sapiens]                28   4.6  
gi|54607047 glucocerebrosidase precursor [Homo sapiens]                28   4.6  
gi|54607045 glucocerebrosidase precursor [Homo sapiens]                28   4.6  
gi|54607043 glucocerebrosidase precursor [Homo sapiens]                28   4.6  
gi|116256464 hypothetical protein LOC343990 [Homo sapiens]             27   6.0  
gi|116325989 hyperpolarization activated cyclic nucleotide-gated...    27   7.8  
gi|150417984 ATP-binding cassette, sub-family A, member 7 [Homo ...    27   7.8  
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa...    27   7.8  
gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa...    27   7.8  
gi|39725717 coiled-coil domain containing 141 [Homo sapiens]           27   7.8  

>gi|239743857 PREDICTED: hypothetical protein XP_002342979 [Homo
           sapiens]
          Length = 163

 Score =  336 bits (861), Expect = 6e-93
 Identities = 163/163 (100%), Positives = 163/163 (100%)

Query: 1   MLISSHQSLVTEPVFQRKPETHAGSYRVPSACTFKMLALLKAVWVLHVAWDSKGKEEAAK 60
           MLISSHQSLVTEPVFQRKPETHAGSYRVPSACTFKMLALLKAVWVLHVAWDSKGKEEAAK
Sbjct: 1   MLISSHQSLVTEPVFQRKPETHAGSYRVPSACTFKMLALLKAVWVLHVAWDSKGKEEAAK 60

Query: 61  RQLLMRKNSYCFLIYILQVRKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQTEPS 120
           RQLLMRKNSYCFLIYILQVRKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQTEPS
Sbjct: 61  RQLLMRKNSYCFLIYILQVRKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQTEPS 120

Query: 121 VLNLHQLSPGFSMRTHELESHHVSMVHSNWRRTIPAAWQEWLV 163
           VLNLHQLSPGFSMRTHELESHHVSMVHSNWRRTIPAAWQEWLV
Sbjct: 121 VLNLHQLSPGFSMRTHELESHHVSMVHSNWRRTIPAAWQEWLV 163


>gi|239755066 PREDICTED: similar to tight junction protein 2 (zona
           occludens 2) [Homo sapiens]
          Length = 163

 Score =  333 bits (855), Expect = 3e-92
 Identities = 162/163 (99%), Positives = 162/163 (99%)

Query: 1   MLISSHQSLVTEPVFQRKPETHAGSYRVPSACTFKMLALLKAVWVLHVAWDSKGKEEAAK 60
           MLISSHQSLVTEPVFQRKPETHAGSYRVPSACTFKMLALLKAVWVLHVAWDSKGKEEAAK
Sbjct: 1   MLISSHQSLVTEPVFQRKPETHAGSYRVPSACTFKMLALLKAVWVLHVAWDSKGKEEAAK 60

Query: 61  RQLLMRKNSYCFLIYILQVRKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQTEPS 120
           RQLLMRKNSYCFLIYILQVRKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQ EPS
Sbjct: 61  RQLLMRKNSYCFLIYILQVRKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQIEPS 120

Query: 121 VLNLHQLSPGFSMRTHELESHHVSMVHSNWRRTIPAAWQEWLV 163
           VLNLHQLSPGFSMRTHELESHHVSMVHSNWRRTIPAAWQEWLV
Sbjct: 121 VLNLHQLSPGFSMRTHELESHHVSMVHSNWRRTIPAAWQEWLV 163


>gi|239749588 PREDICTED: hypothetical protein XP_002347097 [Homo
           sapiens]
          Length = 163

 Score =  333 bits (855), Expect = 3e-92
 Identities = 162/163 (99%), Positives = 162/163 (99%)

Query: 1   MLISSHQSLVTEPVFQRKPETHAGSYRVPSACTFKMLALLKAVWVLHVAWDSKGKEEAAK 60
           MLISSHQSLVTEPVFQRKPETHAGSYRVPSACTFKMLALLKAVWVLHVAWDSKGKEEAAK
Sbjct: 1   MLISSHQSLVTEPVFQRKPETHAGSYRVPSACTFKMLALLKAVWVLHVAWDSKGKEEAAK 60

Query: 61  RQLLMRKNSYCFLIYILQVRKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQTEPS 120
           RQLLMRKNSYCFLIYILQVRKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQ EPS
Sbjct: 61  RQLLMRKNSYCFLIYILQVRKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQIEPS 120

Query: 121 VLNLHQLSPGFSMRTHELESHHVSMVHSNWRRTIPAAWQEWLV 163
           VLNLHQLSPGFSMRTHELESHHVSMVHSNWRRTIPAAWQEWLV
Sbjct: 121 VLNLHQLSPGFSMRTHELESHHVSMVHSNWRRTIPAAWQEWLV 163


>gi|40254988 LSM domain containing 1 [Homo sapiens]
          Length = 173

 Score = 29.3 bits (64), Expect = 1.6
 Identities = 32/100 (32%), Positives = 48/100 (48%), Gaps = 11/100 (11%)

Query: 45  VLHVAWDSKGKEE--AAKRQLLMRKNSYCFLIYILQVRKQNTDFGPLKQV---TGSDCSV 99
           +LH A DS G+ E  AA+R    R+     L   +++R   TD   L      T  DC+V
Sbjct: 70  LLHPAQDSDGEREDSAAERA---RQQLEALLNKTMRIRM--TDGRTLVGCFLCTDRDCNV 124

Query: 100 LLNSEQKATDSSNPVPQTEPSVLNLHQLSPGFSMRTHELE 139
           +L S Q+    S+     EP VL L  + PG  + + E++
Sbjct: 125 ILGSAQEFLKPSDSFSAGEPRVLGL-AMVPGHHIVSIEVQ 163


>gi|116256481 TNFAIP3 interacting protein 1 [Homo sapiens]
          Length = 636

 Score = 28.9 bits (63), Expect = 2.1
 Identities = 19/64 (29%), Positives = 28/64 (43%), Gaps = 3/64 (4%)

Query: 86  FGPLKQVTGSDCSVLLNSEQKATDSSNPVPQTEPSVLNLHQLSPGFSMRTHELESHHVSM 145
           F PL ++TG D +V  +    A  S  P P  +P        S  F + T E ++   S 
Sbjct: 83  FDPLAELTGKDSNVTASPTAPACPSDKPAPVQKPPSSG---TSSEFEVVTPEEQNSPESS 139

Query: 146 VHSN 149
            H+N
Sbjct: 140 SHAN 143


>gi|21717832 sperm equatorial segment protein 1 [Homo sapiens]
          Length = 350

 Score = 28.9 bits (63), Expect = 2.1
 Identities = 10/41 (24%), Positives = 26/41 (63%)

Query: 80  RKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQTEPS 120
           +K++T+  P   +  ++ S++L++E+   ++  P P+ EP+
Sbjct: 112 KKKHTESTPFWSIKPNNVSIVLHAEEPYIENEEPEPEPEPA 152


>gi|46410931 attractin-like 1 [Homo sapiens]
          Length = 1379

 Score = 28.5 bits (62), Expect = 2.7
 Identities = 15/63 (23%), Positives = 30/63 (47%), Gaps = 3/63 (4%)

Query: 31   ACTFKMLALLKAVW-VLHVAWDSKGKEEAAKRQLLMRKNSYCFLIYILQVRKQNTDF--G 87
            +C   +L +   VW +    W S+ +E+  + +  M    +  +   L+V  + T+F  G
Sbjct: 1239 SCFLSLLLVAAVVWKIKQTCWASRRREQLLRERQQMASRPFASVDVALEVGAEQTEFLRG 1298

Query: 88   PLK 90
            PL+
Sbjct: 1299 PLE 1301


>gi|54607051 glucocerebrosidase precursor [Homo sapiens]
          Length = 536

 Score = 27.7 bits (60), Expect = 4.6
 Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 4/57 (7%)

Query: 80  RKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQTEPSVLNLHQLSPGFSMRTH 136
           +K + D   L    GS   V+LN   K      P+   +P+V  L  +SPG+S+ T+
Sbjct: 479 QKNDLDAVALMHPDGSAVVVVLNRSSKDV----PLTIKDPAVGFLETISPGYSIHTY 531


>gi|54607049 glucocerebrosidase precursor [Homo sapiens]
          Length = 536

 Score = 27.7 bits (60), Expect = 4.6
 Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 4/57 (7%)

Query: 80  RKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQTEPSVLNLHQLSPGFSMRTH 136
           +K + D   L    GS   V+LN   K      P+   +P+V  L  +SPG+S+ T+
Sbjct: 479 QKNDLDAVALMHPDGSAVVVVLNRSSKDV----PLTIKDPAVGFLETISPGYSIHTY 531


>gi|54607047 glucocerebrosidase precursor [Homo sapiens]
          Length = 536

 Score = 27.7 bits (60), Expect = 4.6
 Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 4/57 (7%)

Query: 80  RKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQTEPSVLNLHQLSPGFSMRTH 136
           +K + D   L    GS   V+LN   K      P+   +P+V  L  +SPG+S+ T+
Sbjct: 479 QKNDLDAVALMHPDGSAVVVVLNRSSKDV----PLTIKDPAVGFLETISPGYSIHTY 531


>gi|54607045 glucocerebrosidase precursor [Homo sapiens]
          Length = 536

 Score = 27.7 bits (60), Expect = 4.6
 Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 4/57 (7%)

Query: 80  RKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQTEPSVLNLHQLSPGFSMRTH 136
           +K + D   L    GS   V+LN   K      P+   +P+V  L  +SPG+S+ T+
Sbjct: 479 QKNDLDAVALMHPDGSAVVVVLNRSSKDV----PLTIKDPAVGFLETISPGYSIHTY 531


>gi|54607043 glucocerebrosidase precursor [Homo sapiens]
          Length = 536

 Score = 27.7 bits (60), Expect = 4.6
 Identities = 18/57 (31%), Positives = 28/57 (49%), Gaps = 4/57 (7%)

Query: 80  RKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQTEPSVLNLHQLSPGFSMRTH 136
           +K + D   L    GS   V+LN   K      P+   +P+V  L  +SPG+S+ T+
Sbjct: 479 QKNDLDAVALMHPDGSAVVVVLNRSSKDV----PLTIKDPAVGFLETISPGYSIHTY 531


>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
          Length = 962

 Score = 27.3 bits (59), Expect = 6.0
 Identities = 20/90 (22%), Positives = 40/90 (44%), Gaps = 3/90 (3%)

Query: 56  EEAAKRQLLMRKNSYCFLIYILQVRKQ-NTDFGPLKQVTGSDCSVLLNSEQKATDSSNPV 114
           ++A +   +  + + C  I  LQ++ Q N   GP     G       ++   + D    +
Sbjct: 103 QDATRPVRVFSQENVCDRIKALQLKIQCNVKMGPPPPPGGLPAKRGEDAGMSSEDDG--L 160

Query: 115 PQTEPSVLNLHQLSPGFSMRTHELESHHVS 144
           P++ P +  LH + PG +++   +   HVS
Sbjct: 161 PRSPPEMSLLHDVGPGTTIKVSVVSPDHVS 190


>gi|116325989 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 1 [Homo sapiens]
          Length = 890

 Score = 26.9 bits (58), Expect = 7.8
 Identities = 16/62 (25%), Positives = 29/62 (46%), Gaps = 1/62 (1%)

Query: 93  TGSDCSVLLNSEQKATDSSNPVPQTEPSVLNLHQLSPGFSMRTHELESHHVSMVHSNWRR 152
           T S  S++    Q+    S P PQT+P   +    +PG S   +E+     ++ ++N  R
Sbjct: 723 TASQLSLMQQQPQQQVQQSQP-PQTQPQQPSPQPQTPGSSTPKNEVHKSTQALHNTNLTR 781

Query: 153 TI 154
            +
Sbjct: 782 EV 783


>gi|150417984 ATP-binding cassette, sub-family A, member 7 [Homo
           sapiens]
          Length = 2146

 Score = 26.9 bits (58), Expect = 7.8
 Identities = 41/127 (32%), Positives = 58/127 (45%), Gaps = 16/127 (12%)

Query: 37  LALLKAVWVLHVAWDSKGKEEAAKRQLLMRKNSYCFLIYILQVRKQNTDFGPLKQVTGSD 96
           LAL +A   LH   ++   E+ A+  L +R  S   L  +LQ R + T  GPL+ ++ + 
Sbjct: 171 LALGQAQEPLHSLLEAA--EDLAQELLALR--SLVELRALLQ-RPRGTS-GPLELLSEAL 224

Query: 97  CSVLLNSEQ--------KATDSSNPVPQTEPSVLNLHQLSPGFSMRTHELESHHVSMVHS 148
           CSV   S          +A+D    V Q   S L    LSP  S     L+SH +S +  
Sbjct: 225 CSVRGPSSTVGPSLNWYEASDLMELVGQEPESALPDSSLSPACSELIGALDSHPLSRL-- 282

Query: 149 NWRRTIP 155
            WRR  P
Sbjct: 283 LWRRLKP 289


>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
           sapiens]
          Length = 1220

 Score = 26.9 bits (58), Expect = 7.8
 Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 8/81 (9%)

Query: 20  ETHAGSYRVPSACTFKMLALLKAVWVLHVAWDSK----GKEEAAKRQLLMRKNSYCFLIY 75
           +TH      PSA T K+L LL     ++ A+ +K     KE A  RQ +  K     L +
Sbjct: 492 DTHYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQ-VGNKTECALLGF 550

Query: 76  ILQVRKQNTDFGPLKQVTGSD 96
           +L +++   DF P+++    D
Sbjct: 551 VLDLKR---DFQPVREQIPED 568


>gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo
           sapiens]
          Length = 1173

 Score = 26.9 bits (58), Expect = 7.8
 Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 8/81 (9%)

Query: 20  ETHAGSYRVPSACTFKMLALLKAVWVLHVAWDSK----GKEEAAKRQLLMRKNSYCFLIY 75
           +TH      PSA T K+L LL     ++ A+ +K     KE A  RQ +  K     L +
Sbjct: 492 DTHYKEIPAPSALTPKILDLLVHAISINSAYTTKILPPEKEGALPRQ-VGNKTECALLGF 550

Query: 76  ILQVRKQNTDFGPLKQVTGSD 96
           +L +++   DF P+++    D
Sbjct: 551 VLDLKR---DFQPVREQIPED 568


>gi|39725717 coiled-coil domain containing 141 [Homo sapiens]
          Length = 875

 Score = 26.9 bits (58), Expect = 7.8
 Identities = 21/106 (19%), Positives = 41/106 (38%), Gaps = 18/106 (16%)

Query: 37  LALLKAVWVLHVAWDSKGKEEAAKRQLLMRKNSYCF------------------LIYILQ 78
           L+LL+  W L       GK++ A  +  ++K S+                    L +IL 
Sbjct: 88  LSLLRLAWQLKATESKPGKQQWAAFKEQLKKTSHNLKLLQEALMPVSALDLGGSLQFILD 147

Query: 79  VRKQNTDFGPLKQVTGSDCSVLLNSEQKATDSSNPVPQTEPSVLNL 124
           +R++  D  P  Q    +   ++   ++ T    PV +    + +L
Sbjct: 148 LRQKWNDMKPQFQQLNDEVQYIMKESEELTGRGAPVKEKSQQLKDL 193


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.129    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,918,263
Number of Sequences: 37866
Number of extensions: 291221
Number of successful extensions: 640
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 635
Number of HSP's gapped (non-prelim): 18
length of query: 163
length of database: 18,247,518
effective HSP length: 94
effective length of query: 69
effective length of database: 14,688,114
effective search space: 1013479866
effective search space used: 1013479866
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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