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Search of human proteins with 116284390
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116284390 glutamate receptor, ionotrophic, AMPA 4 isoform 3
precursor [Homo sapiens]
(433 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116284390 glutamate receptor, ionotrophic, AMPA 4 isoform 3 p... 877 0.0
gi|164419739 glutamate receptor, ionotrophic, AMPA 4 isoform 3 p... 877 0.0
gi|164419736 glutamate receptor, ionotrophic, AMPA 4 isoform 2 p... 857 0.0
gi|164419734 glutamate receptor, ionotrophic, AMPA 4 isoform 1 p... 857 0.0
gi|163659858 glutamate receptor, ionotrophic, AMPA 3 isoform 2 p... 546 e-155
gi|163659856 glutamate receptor, ionotrophic, AMPA 3 isoform 1 p... 546 e-155
gi|134304848 glutamate receptor, ionotropic, AMPA 2 isoform 2 pr... 514 e-146
gi|74275354 glutamate receptor, ionotropic, AMPA 2 isoform 1 pre... 514 e-146
gi|134304851 glutamate receptor, ionotropic, AMPA 2 isoform 3 [H... 477 e-135
gi|167001484 glutamate receptor, ionotropic, AMPA 1 isoform 2 [H... 454 e-128
gi|167001419 glutamate receptor, ionotropic, AMPA 1 isoform 1 [H... 454 e-128
gi|28605145 glutamate receptor, ionotropic, kainate 3 precursor ... 151 1e-36
gi|28416444 glutamate receptor, ionotropic, kainate 1 isoform 2 ... 145 7e-35
gi|4504117 glutamate receptor, ionotropic, kainate 1 isoform 1 p... 136 4e-32
gi|11386137 glutamate receptor, ionotropic, kainate 2 isoform 1 ... 135 9e-32
gi|28559003 glutamate receptor, ionotropic, kainate 2 isoform 2 ... 135 9e-32
gi|29029597 glutamate receptor KA2 precursor [Homo sapiens] 86 5e-17
gi|157384977 glutamate receptor, ionotropic, delta 2 [Homo sapiens] 85 1e-16
gi|29029595 glutamate receptor KA1 precursor [Homo sapiens] 76 5e-14
gi|55770852 glutamate receptor, ionotropic, delta 1 precursor [H... 69 8e-12
gi|167003331 N-methyl-D-aspartate receptor subunit 2B precursor ... 36 0.078
gi|112789566 taste receptor, type 1, member 2 [Homo sapiens] 29 7.3
gi|87116668 hypothetical protein LOC9870 [Homo sapiens] 29 7.3
>gi|116284390 glutamate receptor, ionotrophic, AMPA 4 isoform 3
precursor [Homo sapiens]
Length = 433
Score = 877 bits (2266), Expect = 0.0
Identities = 433/433 (100%), Positives = 433/433 (100%)
Query: 1 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA
Sbjct: 1 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
Query: 61 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP
Sbjct: 61 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
Query: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH
Sbjct: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
Query: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240
VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA
Sbjct: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240
Query: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300
NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL
Sbjct: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300
Query: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360
TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN
Sbjct: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360
Query: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420
VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT
Sbjct: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420
Query: 421 TIMPLMKNPILRN 433
TIMPLMKNPILRN
Sbjct: 421 TIMPLMKNPILRN 433
>gi|164419739 glutamate receptor, ionotrophic, AMPA 4 isoform 3
precursor [Homo sapiens]
Length = 433
Score = 877 bits (2266), Expect = 0.0
Identities = 433/433 (100%), Positives = 433/433 (100%)
Query: 1 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA
Sbjct: 1 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
Query: 61 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP
Sbjct: 61 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
Query: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH
Sbjct: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
Query: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240
VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA
Sbjct: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240
Query: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300
NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL
Sbjct: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300
Query: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360
TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN
Sbjct: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360
Query: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420
VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT
Sbjct: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420
Query: 421 TIMPLMKNPILRN 433
TIMPLMKNPILRN
Sbjct: 421 TIMPLMKNPILRN 433
>gi|164419736 glutamate receptor, ionotrophic, AMPA 4 isoform 2
precursor [Homo sapiens]
Length = 884
Score = 857 bits (2213), Expect = 0.0
Identities = 423/423 (100%), Positives = 423/423 (100%)
Query: 1 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA
Sbjct: 1 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
Query: 61 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP
Sbjct: 61 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
Query: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH
Sbjct: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
Query: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240
VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA
Sbjct: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240
Query: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300
NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL
Sbjct: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300
Query: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360
TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN
Sbjct: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360
Query: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420
VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT
Sbjct: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420
Query: 421 TIM 423
TIM
Sbjct: 421 TIM 423
>gi|164419734 glutamate receptor, ionotrophic, AMPA 4 isoform 1
precursor [Homo sapiens]
Length = 902
Score = 857 bits (2213), Expect = 0.0
Identities = 423/423 (100%), Positives = 423/423 (100%)
Query: 1 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA
Sbjct: 1 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
Query: 61 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP
Sbjct: 61 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
Query: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH
Sbjct: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
Query: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240
VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA
Sbjct: 181 VSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIA 240
Query: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300
NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL
Sbjct: 241 NLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPKYTSAL 300
Query: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360
TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN
Sbjct: 301 TYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGN 360
Query: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420
VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT
Sbjct: 361 VQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVT 420
Query: 421 TIM 423
TIM
Sbjct: 421 TIM 423
>gi|163659858 glutamate receptor, ionotrophic, AMPA 3 isoform 2
precursor [Homo sapiens]
Length = 894
Score = 546 bits (1407), Expect = e-155
Identities = 253/422 (59%), Positives = 341/422 (80%), Gaps = 3/422 (0%)
Query: 4 ISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFN 63
+ R + L G G + G FP+++ IGGLF+RNT QE++AFR A+ L+NT+ N +E PF+
Sbjct: 11 VLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFH 70
Query: 64 LVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFP 123
L HVD+++++NSF+VTNAFCSQ+SRGV+AIFG YD+ S++TLTSFC ALH S +TPSFP
Sbjct: 71 LNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFP 130
Query: 124 TEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSA 183
T+ + QFV+Q+RP+L+GA+LSLL HY+W FV+LYDT+RG+SILQAIME A QN W V+A
Sbjct: 131 TDADVQFVIQMRPALKGAILSLLGHYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTA 190
Query: 184 ICVENFNDV-SYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANL 242
V N DV +R+++EE+DRRQEK+++IDCE+ER+ ILEQ+V +GKH +GYHY++ANL
Sbjct: 191 RSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANL 250
Query: 243 GFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-KYTSALT 301
GF DI LER +HGGAN+TGFQ+V+ PMV + + RW +LD+RE+P ++ P KYTSALT
Sbjct: 251 GFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALT 310
Query: 302 YDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNV 361
+D +LV+AE FR LRRQ++D+SRRG+AGDCLANPA PW QGID+ER LK V++QG+TGN+
Sbjct: 311 HDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNI 370
Query: 362 QFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTT 421
QFD YGRR NYT+DV+E+K +G RK GYWN+ ++ V D + ND+A+ ENRT+VVTT
Sbjct: 371 QFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSD-QQISNDSASSENRTIVVTT 429
Query: 422 IM 423
I+
Sbjct: 430 IL 431
>gi|163659856 glutamate receptor, ionotrophic, AMPA 3 isoform 1
precursor [Homo sapiens]
Length = 894
Score = 546 bits (1407), Expect = e-155
Identities = 253/422 (59%), Positives = 341/422 (80%), Gaps = 3/422 (0%)
Query: 4 ISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFN 63
+ R + L G G + G FP+++ IGGLF+RNT QE++AFR A+ L+NT+ N +E PF+
Sbjct: 11 VLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNTNQNTTEKPFH 70
Query: 64 LVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFP 123
L HVD+++++NSF+VTNAFCSQ+SRGV+AIFG YD+ S++TLTSFC ALH S +TPSFP
Sbjct: 71 LNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFP 130
Query: 124 TEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSA 183
T+ + QFV+Q+RP+L+GA+LSLL HY+W FV+LYDT+RG+SILQAIME A QN W V+A
Sbjct: 131 TDADVQFVIQMRPALKGAILSLLGHYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTA 190
Query: 184 ICVENFNDV-SYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANL 242
V N DV +R+++EE+DRRQEK+++IDCE+ER+ ILEQ+V +GKH +GYHY++ANL
Sbjct: 191 RSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANL 250
Query: 243 GFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-KYTSALT 301
GF DI LER +HGGAN+TGFQ+V+ PMV + + RW +LD+RE+P ++ P KYTSALT
Sbjct: 251 GFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKNAPLKYTSALT 310
Query: 302 YDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNV 361
+D +LV+AE FR LRRQ++D+SRRG+AGDCLANPA PW QGID+ER LK V++QG+TGN+
Sbjct: 311 HDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKMVQVQGMTGNI 370
Query: 362 QFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTT 421
QFD YGRR NYT+DV+E+K +G RK GYWN+ ++ V D + ND+A+ ENRT+VVTT
Sbjct: 371 QFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSD-QQISNDSASSENRTIVVTT 429
Query: 422 IM 423
I+
Sbjct: 430 IL 431
>gi|134304848 glutamate receptor, ionotropic, AMPA 2 isoform 2
precursor [Homo sapiens]
Length = 883
Score = 514 bits (1325), Expect = e-146
Identities = 239/428 (55%), Positives = 330/428 (77%), Gaps = 11/428 (2%)
Query: 1 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
M+ I VLL WGL G +S+QIGGLF R DQEY+AFR+ + +TS
Sbjct: 1 MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSE----- 55
Query: 61 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
F L PH+DN+E ANSFAVTNAFCSQ+SRGV+AIFG YDK+SV+T+TSFC LH+S ITP
Sbjct: 56 -FRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITP 114
Query: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
SFPT+G FV+Q+RP L+GALLSL+++Y+W+ F +LYD+DRG S LQA+++ A + W
Sbjct: 115 SFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQ 174
Query: 181 VSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYH 236
V+AI V N N D YR L ++L+ ++E++ ++DCE +++ +I++Q++++GKHVKGYH
Sbjct: 175 VTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYH 234
Query: 237 YIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-K 295
YIIANLGF D L + GGANV+GFQ+VD++ +V K ++RW L+++EYPG+ T K
Sbjct: 235 YIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIK 294
Query: 296 YTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQ 355
YTSALTYD V VM E FR+LR+Q+I+ISRRGNAGDCLANPA PWGQG+++ER LKQV+++
Sbjct: 295 YTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVE 354
Query: 356 GLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENR 415
GL+GN++FD G+R+NYT+++ ELK+ GPRK+GYW+++DK+V+ GNDT+ +EN+
Sbjct: 355 GLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENK 414
Query: 416 TVVVTTIM 423
TVVVTTI+
Sbjct: 415 TVVVTTIL 422
>gi|74275354 glutamate receptor, ionotropic, AMPA 2 isoform 1
precursor [Homo sapiens]
Length = 883
Score = 514 bits (1325), Expect = e-146
Identities = 239/428 (55%), Positives = 330/428 (77%), Gaps = 11/428 (2%)
Query: 1 MRIISRQIVLLFSGFWGLAMGAFPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEA 60
M+ I VLL WGL G +S+QIGGLF R DQEY+AFR+ + +TS
Sbjct: 1 MQKIMHISVLLSPVLWGLIFGVSSNSIQIGGLFPRGADQEYSAFRVGMVQFSTSE----- 55
Query: 61 PFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITP 120
F L PH+DN+E ANSFAVTNAFCSQ+SRGV+AIFG YDK+SV+T+TSFC LH+S ITP
Sbjct: 56 -FRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSFITP 114
Query: 121 SFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWH 180
SFPT+G FV+Q+RP L+GALLSL+++Y+W+ F +LYD+DRG S LQA+++ A + W
Sbjct: 115 SFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEKKWQ 174
Query: 181 VSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYH 236
V+AI V N N D YR L ++L+ ++E++ ++DCE +++ +I++Q++++GKHVKGYH
Sbjct: 175 VTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVKGYH 234
Query: 237 YIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPP-K 295
YIIANLGF D L + GGANV+GFQ+VD++ +V K ++RW L+++EYPG+ T K
Sbjct: 235 YIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTTTIK 294
Query: 296 YTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQ 355
YTSALTYD V VM E FR+LR+Q+I+ISRRGNAGDCLANPA PWGQG+++ER LKQV+++
Sbjct: 295 YTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQVQVE 354
Query: 356 GLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENR 415
GL+GN++FD G+R+NYT+++ ELK+ GPRK+GYW+++DK+V+ GNDT+ +EN+
Sbjct: 355 GLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGLENK 414
Query: 416 TVVVTTIM 423
TVVVTTI+
Sbjct: 415 TVVVTTIL 422
>gi|134304851 glutamate receptor, ionotropic, AMPA 2 isoform 3 [Homo
sapiens]
Length = 836
Score = 477 bits (1228), Expect = e-135
Identities = 214/371 (57%), Positives = 299/371 (80%), Gaps = 5/371 (1%)
Query: 58 SEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISL 117
S + F L PH+DN+E ANSFAVTNAFCSQ+SRGV+AIFG YDK+SV+T+TSFC LH+S
Sbjct: 5 STSEFRLTPHIDNLEVANSFAVTNAFCSQFSRGVYAIFGFYDKKSVNTITSFCGTLHVSF 64
Query: 118 ITPSFPTEGESQFVLQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQN 177
ITPSFPT+G FV+Q+RP L+GALLSL+++Y+W+ F +LYD+DRG S LQA+++ A +
Sbjct: 65 ITPSFPTDGTHPFVIQMRPDLKGALLSLIEYYQWDKFAYLYDSDRGLSTLQAVLDSAAEK 124
Query: 178 GWHVSAICVENFN----DVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVK 233
W V+AI V N N D YR L ++L+ ++E++ ++DCE +++ +I++Q++++GKHVK
Sbjct: 125 KWQVTAINVGNINNDKKDEMYRSLFQDLELKKERRVILDCERDKVNDIVDQVITIGKHVK 184
Query: 234 GYHYIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETP 293
GYHYIIANLGF D L + GGANV+GFQ+VD++ +V K ++RW L+++EYPG+ T
Sbjct: 185 GYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIERWSTLEEKEYPGAHTT 244
Query: 294 P-KYTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQV 352
KYTSALTYD V VM E FR+LR+Q+I+ISRRGNAGDCLANPA PWGQG+++ER LKQV
Sbjct: 245 TIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAVPWGQGVEIERALKQV 304
Query: 353 RIQGLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAI 412
+++GL+GN++FD G+R+NYT+++ ELK+ GPRK+GYW+++DK+V+ GNDT+ +
Sbjct: 305 QVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKMVVTLTELPSGNDTSGL 364
Query: 413 ENRTVVVTTIM 423
EN+TVVVTTI+
Sbjct: 365 ENKTVVVTTIL 375
>gi|167001484 glutamate receptor, ionotropic, AMPA 1 isoform 2 [Homo
sapiens]
Length = 906
Score = 454 bits (1167), Expect = e-128
Identities = 218/413 (52%), Positives = 296/413 (71%), Gaps = 9/413 (2%)
Query: 13 SGFWGLAMGA-FPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNI 71
+GF G +GA FP+++QIGGLF QE+ AFR A+ + P L+P +D +
Sbjct: 10 TGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFAL-------SQLTEPPKLLPQIDIV 62
Query: 72 ETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTEGESQFV 131
++SF +T FCSQ+S+GV+AIFG Y++R+V+ LTSFC ALH+ ITPSFP + +QFV
Sbjct: 63 NISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFV 122
Query: 132 LQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFND 191
LQLRP L+ AL+S++DHY+W FV++YD DRG S+LQ +++ A + W V+A+ + +
Sbjct: 123 LQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTTTE 182
Query: 192 VSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLER 251
YR L ++L++++E+ V+DCE ERL IL QI+ + K+ GYHYI+ANLGF DI L +
Sbjct: 183 EGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLNK 242
Query: 252 FIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSE-TPPKYTSALTYDGVLVMAE 310
F GANVTGFQLV++ + K+M +WK D R++ + PKYTSALTYDGV VMAE
Sbjct: 243 FKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVMAE 302
Query: 311 TFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRV 370
F+SLRRQ+IDISRRGNAGDCLANPA PWGQGID++R L+QVR +GLTGNVQF+ GRR
Sbjct: 303 AFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRT 362
Query: 371 NYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTTIM 423
NYT+ V E+K G RK+GYWN+ DK V G D ++++NRT +VTTI+
Sbjct: 363 NYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTIL 415
>gi|167001419 glutamate receptor, ionotropic, AMPA 1 isoform 1 [Homo
sapiens]
Length = 906
Score = 454 bits (1167), Expect = e-128
Identities = 218/413 (52%), Positives = 296/413 (71%), Gaps = 9/413 (2%)
Query: 13 SGFWGLAMGA-FPSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNI 71
+GF G +GA FP+++QIGGLF QE+ AFR A+ + P L+P +D +
Sbjct: 10 TGFLGAVVGANFPNNIQIGGLFPNQQSQEHAAFRFAL-------SQLTEPPKLLPQIDIV 62
Query: 72 ETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTEGESQFV 131
++SF +T FCSQ+S+GV+AIFG Y++R+V+ LTSFC ALH+ ITPSFP + +QFV
Sbjct: 63 NISDSFEMTYRFCSQFSKGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDTSNQFV 122
Query: 132 LQLRPSLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFND 191
LQLRP L+ AL+S++DHY+W FV++YD DRG S+LQ +++ A + W V+A+ + +
Sbjct: 123 LQLRPELQDALISIIDHYKWQKFVYIYDADRGLSVLQKVLDTAAEKNWQVTAVNILTTTE 182
Query: 192 VSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLER 251
YR L ++L++++E+ V+DCE ERL IL QI+ + K+ GYHYI+ANLGF DI L +
Sbjct: 183 EGYRMLFQDLEKKKERLVVVDCESERLNAILGQIIKLEKNGIGYHYILANLGFMDIDLNK 242
Query: 252 FIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSE-TPPKYTSALTYDGVLVMAE 310
F GANVTGFQLV++ + K+M +WK D R++ + PKYTSALTYDGV VMAE
Sbjct: 243 FKESGANVTGFQLVNYTDTIPAKIMQQWKNSDARDHTRVDWKRPKYTSALTYDGVKVMAE 302
Query: 311 TFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRV 370
F+SLRRQ+IDISRRGNAGDCLANPA PWGQGID++R L+QVR +GLTGNVQF+ GRR
Sbjct: 303 AFQSLRRQRIDISRRGNAGDCLANPAVPWGQGIDIQRALQQVRFEGLTGNVQFNEKGRRT 362
Query: 371 NYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTTIM 423
NYT+ V E+K G RK+GYWN+ DK V G D ++++NRT +VTTI+
Sbjct: 363 NYTLHVIEMKHDGIRKIGYWNEDDKFVPAATDAQAGGDNSSVQNRTYIVTTIL 415
>gi|28605145 glutamate receptor, ionotropic, kainate 3 precursor
[Homo sapiens]
Length = 919
Score = 151 bits (381), Expect = 1e-36
Identities = 117/438 (26%), Positives = 201/438 (45%), Gaps = 38/438 (8%)
Query: 10 LLFSGFWGLAMGAFPSSVQIGGLF---------IRNTDQEYTAFRLAIFLHNTS--PNAS 58
LL FW P ++IGG+F + N ++ F I N + PN +
Sbjct: 19 LLVCAFWIPDSRGMPHVIRIGGIFEYADGPNAQVMNAEEHAFRFSANIINRNRTLLPNTT 78
Query: 59 EAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSAL---HI 115
L + I +SF T C Q + GV AIFG + + S C+AL HI
Sbjct: 79 -----LTYDIQRIHFHDSFEATKKACDQLALGVVAIFGPSQGSCTNAVQSICNALEVPHI 133
Query: 116 SLITPSFPTEGESQFVLQLRP---SLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIME 172
L P + + F + L P SL A+L L+ + +W +YD G LQ ++
Sbjct: 134 QLRWKHHPLDNKDTFYVNLYPDYASLSHAILDLVQYLKWRSATVVYDDSTGLIRLQELIM 193
Query: 173 KAGQNGWHVSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHV 232
+ + + +D S R LL+E+ R +E + + DC IL+Q +++G
Sbjct: 194 APSRYNIRLKIRQLPIDSDDS-RPLLKEMKRGREFRIIFDCSHTMAAQILKQAMAMGMMT 252
Query: 233 KGYHYIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSET 292
+ YH+I L + LE + + G N+TGF++++ + P V ++++W + P SE+
Sbjct: 253 EYYHFIFTTLDLYALDLEPYRYSGVNLTGFRILNVDNPHVSAIVEKWSMERLQAAPRSES 312
Query: 293 -----PPKYTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMER 347
+AL YD V +++ ++ + + N+ C + A W G
Sbjct: 313 GLLDGVMMTDAALLYDAVHIVSVCYQRAPQMTV------NSLQCHRHKA--WRFGGRFMN 364
Query: 348 TLKQVRIQGLTGNVQFDH-YGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLG 406
+K+ + +GLTG + F+ G R ++ +D+ LK G KVG W+ D L + + G
Sbjct: 365 FIKEAQWEGLTGRIVFNKTSGLRTDFDLDIISLKEDGLEKVGVWSPADGLNITEVAKGRG 424
Query: 407 -NDTAAIENRTVVVTTIM 423
N T ++ NR+++VTT++
Sbjct: 425 PNVTDSLTNRSLIVTTVL 442
>gi|28416444 glutamate receptor, ionotropic, kainate 1 isoform 2
precursor [Homo sapiens]
Length = 905
Score = 145 bits (366), Expect = 7e-35
Identities = 110/416 (26%), Positives = 190/416 (45%), Gaps = 25/416 (6%)
Query: 24 PSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPF---NLVPHVDNIETANSFAVT 80
P ++IGG+F ++ LA TS N + L + I +SF +
Sbjct: 34 PQVLRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQRINLFDSFEAS 93
Query: 81 NAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFP---TEGESQFVLQLRP- 136
C Q + GV A+FG SV + S C+AL + I + + + F + L P
Sbjct: 94 RRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPD 153
Query: 137 --SLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFNDVSY 194
++ A+L L+ +Y W +Y+ G LQ +++ + + + + N +
Sbjct: 154 YAAISRAILDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDA- 212
Query: 195 RQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLERFIH 254
+ LL+E+ + +E + DC E IL+QI+ +G + YHY L + LE + +
Sbjct: 213 KPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRY 272
Query: 255 GGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSET-----PPKYTSALTYDGVLVMA 309
G N+TGF+L++ + P V ++++W + P ET +AL YD V ++A
Sbjct: 273 SGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVA 332
Query: 310 ETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDH-YGR 368
S R ++ +S + PW G +K+ R GLTG++ F+ G
Sbjct: 333 --IASHRASQLTVS------SLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGL 384
Query: 369 RVNYTMDVFELKSTGPRKVGYWNDMDKLVLI-QDVPTLGNDTAAIENRTVVVTTIM 423
R ++ +D+ LK G K+G WN L + + N T ++ NRT++VTTI+
Sbjct: 385 RKDFDLDIISLKEEGTEKIGIWNSNSGLNMTDSNKDKSSNITDSLANRTLIVTTIL 440
>gi|4504117 glutamate receptor, ionotropic, kainate 1 isoform 1
precursor [Homo sapiens]
Length = 918
Score = 136 bits (342), Expect = 4e-32
Identities = 110/431 (25%), Positives = 191/431 (44%), Gaps = 40/431 (9%)
Query: 24 PSSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPF---NLVPHVDNIETANSFAVT 80
P ++IGG+F ++ LA TS N + L + I +SF +
Sbjct: 34 PQVLRIGGIFETVENEPVNVEELAFKFAVTSINRNRTLMPNTTLTYDIQRINLFDSFEAS 93
Query: 81 NAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFP---TEGESQFVLQLRP- 136
C Q + GV A+FG SV + S C+AL + I + + + F + L P
Sbjct: 94 RRACDQLALGVAALFGPSHSSSVSAVQSICNALEVPHIQTRWKHPSVDNKDLFYINLYPD 153
Query: 137 --SLRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFNDVSY 194
++ A+L L+ +Y W +Y+ G LQ +++ + + + + N +
Sbjct: 154 YAAISRAILDLVLYYNWKTVTVVYEDSTGLIRLQELIKAPSRYNIKIKIRQLPSGNKDA- 212
Query: 195 RQLLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLERFIH 254
+ LL+E+ + +E + DC E IL+QI+ +G + YHY L + LE + +
Sbjct: 213 KPLLKEMKKGKEFYVIFDCSHETAAEILKQILFMGMMTEYYHYFFTTLDLFALDLELYRY 272
Query: 255 GGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSET-----PPKYTSALTYDGVLVMA 309
G N+TGF+L++ + P V ++++W + P ET +AL YD V ++A
Sbjct: 273 SGVNMTGFRLLNIDNPHVSSIIEKWSMERLQAPPRPETGLLDGMMTTEAALMYDAVYMVA 332
Query: 310 ETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDH-YGR 368
S R ++ +S + PW G +K+ R GLTG++ F+ G
Sbjct: 333 --IASHRASQLTVS------SLQCHRHKPWRLGPRFMNLIKEARWDGLTGHITFNKTNGL 384
Query: 369 RVNYTMDVFELKSTGP---------------RKVGYWNDMDKLVLI-QDVPTLGNDTAAI 412
R ++ +D+ LK G +K+G WN L + + N T ++
Sbjct: 385 RKDFDLDIISLKEEGTEKAAGEVSKHLYKVWKKIGIWNSNSGLNMTDSNKDKSSNITDSL 444
Query: 413 ENRTVVVTTIM 423
NRT++VTTI+
Sbjct: 445 ANRTLIVTTIL 455
>gi|11386137 glutamate receptor, ionotropic, kainate 2 isoform 1
precursor [Homo sapiens]
Length = 908
Score = 135 bits (339), Expect = 9e-32
Identities = 115/443 (25%), Positives = 194/443 (43%), Gaps = 37/443 (8%)
Query: 3 IISRQIVLLFSGFW-GLAMGAFPSSVQIGGLF----IRNTDQEYTAFRLAIFLHNTS--- 54
+ R + LL W G + G ++ GG+F E AFR A+ N +
Sbjct: 12 VFRRTVKLLLCLLWIGYSQGT-THVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTL 70
Query: 55 -PNASEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSAL 113
PN + L I +SF + C Q S GV AIFG S + + S C+AL
Sbjct: 71 LPNTT-----LTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNAL 125
Query: 114 ---HISLITPSFPTEGESQFVLQLRP---SLRGALLSLLDHYEWNCFVFLYDTDRGYSIL 167
HI ++ + F + L P SL A+L L+ ++W +YD G L
Sbjct: 126 GVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRL 185
Query: 168 QAIMEKAGQNGWHVSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVS 227
Q +++ + + I + + LL+E+ R +E + DC E IL+Q ++
Sbjct: 186 QELIKAPSRYNLRLK-IRQLPADTKDAKPLLKEMKRGKEFHVIFDCSHEMAAGILKQALA 244
Query: 228 VGKHVKGYHYIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRW--KKLDQR 285
+G + YHYI L + +E + + G N+TGF++++ V ++++W ++L
Sbjct: 245 MGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKWSMERLQAP 304
Query: 286 EYPGSETPPKY---TSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQG 342
P S + +AL YD V V++ + + + N PW G
Sbjct: 305 PKPDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTV--------SSLQCNRHKPWRFG 356
Query: 343 IDMERTLKQVRIQGLTGNVQFDH-YGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQD 401
+K+ +GLTG + F+ G R ++ +DV LK G K+G W+ L + +
Sbjct: 357 TRFMSLIKEAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTES 416
Query: 402 VP-TLGNDTAAIENRTVVVTTIM 423
N T ++ NR+++VTTI+
Sbjct: 417 QKGKPANITDSLSNRSLIVTTIL 439
>gi|28559003 glutamate receptor, ionotropic, kainate 2 isoform 2
precursor [Homo sapiens]
Length = 869
Score = 135 bits (339), Expect = 9e-32
Identities = 115/443 (25%), Positives = 194/443 (43%), Gaps = 37/443 (8%)
Query: 3 IISRQIVLLFSGFW-GLAMGAFPSSVQIGGLF----IRNTDQEYTAFRLAIFLHNTS--- 54
+ R + LL W G + G ++ GG+F E AFR A+ N +
Sbjct: 12 VFRRTVKLLLCLLWIGYSQGT-THVLRFGGIFEYVESGPMGAEELAFRFAVNTINRNRTL 70
Query: 55 -PNASEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSAL 113
PN + L I +SF + C Q S GV AIFG S + + S C+AL
Sbjct: 71 LPNTT-----LTYDTQKINLYDSFEASKKACDQLSLGVAAIFGPSHSSSANAVQSICNAL 125
Query: 114 ---HISLITPSFPTEGESQFVLQLRP---SLRGALLSLLDHYEWNCFVFLYDTDRGYSIL 167
HI ++ + F + L P SL A+L L+ ++W +YD G L
Sbjct: 126 GVPHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAILDLVQFFKWKTVTVVYDDSTGLIRL 185
Query: 168 QAIMEKAGQNGWHVSAICVENFNDVSYRQLLEELDRRQEKKFVIDCEIERLQNILEQIVS 227
Q +++ + + I + + LL+E+ R +E + DC E IL+Q ++
Sbjct: 186 QELIKAPSRYNLRLK-IRQLPADTKDAKPLLKEMKRGKEFHVIFDCSHEMAAGILKQALA 244
Query: 228 VGKHVKGYHYIIANLGFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRW--KKLDQR 285
+G + YHYI L + +E + + G N+TGF++++ V ++++W ++L
Sbjct: 245 MGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSSIIEKWSMERLQAP 304
Query: 286 EYPGSETPPKY---TSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQG 342
P S + +AL YD V V++ + + + N PW G
Sbjct: 305 PKPDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTV--------SSLQCNRHKPWRFG 356
Query: 343 IDMERTLKQVRIQGLTGNVQFDH-YGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQD 401
+K+ +GLTG + F+ G R ++ +DV LK G K+G W+ L + +
Sbjct: 357 TRFMSLIKEAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPASGLNMTES 416
Query: 402 VP-TLGNDTAAIENRTVVVTTIM 423
N T ++ NR+++VTTI+
Sbjct: 417 QKGKPANITDSLSNRSLIVTTIL 439
>gi|29029597 glutamate receptor KA2 precursor [Homo sapiens]
Length = 980
Score = 86.3 bits (212), Expect = 5e-17
Identities = 95/403 (23%), Positives = 162/403 (40%), Gaps = 44/403 (10%)
Query: 45 RLAIFLHNTSPNAS-EAPFNLVPHVD--NIETANSFAVTNAFCSQYSRGVFAIFGLYDK- 100
RLA+ L N E P VD ++ + + T+ C +GV ++ G
Sbjct: 41 RLALALAREQINGIIEVPAKARVEVDIFELQRDSQYETTDTMCQILPKGVVSVLGPSSSP 100
Query: 101 RSVHTLTSFCSALHISLITPSFPTEGESQFV----LQLRPSLRGALLS---LLDHYEW-- 151
S T++ C I I Q++ + L PS L+ +L + +
Sbjct: 101 ASASTVSHICGEKEIPHIKVGPEETPRLQYLRFASVSLYPSNEDVSLAVSRILKSFNYPS 160
Query: 152 --------NCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENFNDVSYRQLLEELDR 203
C + L + RG+ I + + S +++ D + LL+E+
Sbjct: 161 ASLICAKAECLLRLEELVRGFLISKETL----------SVRMLDDSRDPT--PLLKEIRD 208
Query: 204 RQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLERFIHGGANVTGFQ 263
+ +ID IL + +G Y YI+ + F + L+ + +N+ GF
Sbjct: 209 DKVSTIIIDANASISHLILRKASELGMTSAFYKYILTTMDFPILHLDGIVEDSSNILGFS 268
Query: 264 LVDFNTPMVIKLMDRWKKLDQREYPGSET--PPKYTSALTYDGVLVMAETFRSLRRQKID 321
+ + + P + + R + RE + T P ++AL +D V V+ R L R
Sbjct: 269 MFNTSHPFYPEFV-RSLNMSWRENCEASTYLGPALSAALMFDAVHVVVSAVRELNR---- 323
Query: 322 ISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRVNYTMDVFELKS 381
S+ A W G + L+ V GLTG V+F+ G+R NYT+ + E
Sbjct: 324 -SQEIGVKPLACTSANIWPHGTSLMNYLRMVEYDGLTGRVEFNSKGQRTNYTLRILEKSR 382
Query: 382 TGPRKVGYWNDMDKLVLIQDVPTLG-NDTAAIENRTVVVTTIM 423
G R++G W L + TL N + + N+T+VVTTI+
Sbjct: 383 QGHREIGVW--YSNRTLAMNATTLDINLSQTLANKTLVVTTIL 423
>gi|157384977 glutamate receptor, ionotropic, delta 2 [Homo sapiens]
Length = 1007
Score = 84.7 bits (208), Expect = 1e-16
Identities = 91/432 (21%), Positives = 171/432 (39%), Gaps = 45/432 (10%)
Query: 25 SSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNIETANSFAVTNAFC 84
S + IG +F + ++ FR A+ N + + + V ++ N F C
Sbjct: 25 SIIHIGAIFDESAKKDDEVFRTAVGDLNQNEEILQTE-KITFSVTFVDGNNPFQAVQEAC 83
Query: 85 SQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLI-----TPSFPTEG--------ESQFV 131
++G+ A+ S +L S A+HI + T P G +
Sbjct: 84 ELMNQGILALVSSIGCTSAGSLQSLADAMHIPHLFIQRSTAGTPRSGCGLTRSNRNDDYT 143
Query: 132 LQLRPS--LRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVENF 189
L +RP L +L ++ Y W F+ YD++ +Q ++K Q G V+ VEN
Sbjct: 144 LSVRPPVYLHDVILRVVTEYAWQKFIIFYDSEYDIRGIQEFLDKVSQQGMDVALQKVENN 203
Query: 190 NDVSYRQL-----LEELDRRQE--KKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANL 242
+ L +EEL+R ++ ++ ++ ++ + ++V H+II N
Sbjct: 204 INKMITTLFDTMRIEELNRYRDTLRRAILVMNPATAKSFITEVVETNLVAFDCHWIIINE 263
Query: 243 GFKDISLERFIHGGANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSETPPK------- 295
D+ ++ + ++ ++ P+ + R + + R + PK
Sbjct: 264 EINDVDVQELVR--RSIGRLTIIRQTFPVPQNISQRCFRGNHR-ISSTLCDPKDPFAQNM 320
Query: 296 -YTSALTYDGVLVMAETFRSLRRQKIDISRRGNAG--DCLANPAAPWGQGIDMERTLKQV 352
++ YD VL++A F +K++ + + C+ + PW G M T+K+
Sbjct: 321 EISNLYIYDTVLLLANAF----HKKLEDRKWHSMASLSCIRKNSKPWQGGRSMLETIKKG 376
Query: 353 RIQGLTGNVQFDHYGRRVNYTMDVF-----ELKSTGPRKVGYWNDMDKLVLIQDVPTLGN 407
+ GLTG ++F G N ++ E G RK+G WN + L L N
Sbjct: 377 GVSGLTGELEFGENGGNPNVHFEILGTNYGEELGRGVRKLGCWNPVTGLNGSLTDKKLEN 436
Query: 408 DTAAIENRTVVV 419
+ + R V V
Sbjct: 437 NMRGVVLRVVTV 448
>gi|29029595 glutamate receptor KA1 precursor [Homo sapiens]
Length = 956
Score = 76.3 bits (186), Expect = 5e-14
Identities = 60/240 (25%), Positives = 103/240 (42%), Gaps = 18/240 (7%)
Query: 197 LLEELDRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISLERFIHGG 256
LL+E+ + +I IL + +G Y YI NL F ++ +
Sbjct: 203 LLKEIRDDKTATIIIHANASMSHTILLKAAELGMVSAYYTYIFTNLEFSLQRMDSLVDDR 262
Query: 257 ANVTGFQLVD----FNTPMVIKLMDRWKK-LDQREYPGSETPPKYTSALTYDGVLVMAET 311
N+ GF + + F L W++ D + G P +SAL +D V +
Sbjct: 263 VNILGFSIFNQSHAFFQEFAQSLNQSWQENCDHVPFTG----PALSSALLFDAVYAVVTA 318
Query: 312 FRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLKQVRIQGLTGNVQFDHYGRRVN 371
+ L R S+ A W G + L+ V ++GLTG+++F+ G+R N
Sbjct: 319 VQELNR-----SQEIGVKPLSCGSAQIWQHGTSLMNYLRMVELEGLTGHIEFNSKGQRSN 373
Query: 372 YTMDVFELKSTGPRKVGYWNDMDKLVLIQDVPTLGNDTAAIENRTVVVTTIMPLMKNPIL 431
Y + + + G R++G W+ + L + + N + + N T+VVTTI ++NP L
Sbjct: 374 YALKILQFTRNGFRQIGQWHVAEGLSMDSHL-YASNISDTLFNTTLVVTTI---LENPYL 429
>gi|55770852 glutamate receptor, ionotropic, delta 1 precursor [Homo
sapiens]
Length = 1009
Score = 68.9 bits (167), Expect = 8e-12
Identities = 80/373 (21%), Positives = 142/373 (38%), Gaps = 45/373 (12%)
Query: 25 SSVQIGGLFIRNTDQEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNIETANSFAVTNAFC 84
S + IG +F N ++ F+LA+ + + + ++ + + IE N F C
Sbjct: 22 SIIHIGAIFEENAAKDDRVFQLAVSDLSLNDDILQSE-KITYSIKVIEANNPFQAVQEAC 80
Query: 85 SQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTEGESQFVLQLRPS------- 137
++G+ A+ S + L S A+HI + G + L PS
Sbjct: 81 DLMTQGILALVTSTGCASANALQSLTDAMHIPHLFVQRNPGGSPRTACHLNPSPDGEAYT 140
Query: 138 --------LRGALLSLLDHYEWNCFVFLYDTDRGYSILQAIMEKAGQNGWHVSAICVEN- 188
L +L L+ W FV YD++ LQ+ +++A + G VS V+
Sbjct: 141 LASRPPVRLNDVMLRLVTELRWQKFVMFYDSEYDIRGLQSFLDQASRLGLDVSLQKVDKN 200
Query: 189 ----FNDVSYRQLLEELDRRQE--KKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANL 242
F + EEL+R ++ ++ ++ + + + + V K H++ N
Sbjct: 201 ISHVFTSLFTTMKTEELNRYRDTLRRAILLLSPQGAHSFINEAVETNLASKDSHWVFVNE 260
Query: 243 GFKDISLERFIHGG-----------ANVTGFQLVDFNTPMVIKLMDRWKKLDQREYPGSE 291
D + +H + Q N + L+ D +E G
Sbjct: 261 EISDPEILDLVHSALGRMTVVRQIFPSAKDNQKCTRNNHRISSLL-----CDPQE--GYL 313
Query: 292 TPPKYTSALTYDGVLVMAETF-RSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERTLK 350
+ ++ YD VL++A F R L +K N C+ PW G M T+K
Sbjct: 314 QMLQISNLYLYDSVLMLANAFHRKLEDRKWHSMASLN---CIRKSTKPWNGGRSMLDTIK 370
Query: 351 QVRIQGLTGNVQF 363
+ I GLTG ++F
Sbjct: 371 KGHITGLTGVMEF 383
>gi|167003331 N-methyl-D-aspartate receptor subunit 2B precursor
[Homo sapiens]
Length = 1484
Score = 35.8 bits (81), Expect = 0.078
Identities = 35/161 (21%), Positives = 64/161 (39%), Gaps = 20/161 (12%)
Query: 99 DKRSVHTLTSFCSALHISLITPSFPTEG----------ESQFVLQLRPSLR---GALLSL 145
D+ ++ + F SA +TP G ES Q PS+ +L++
Sbjct: 104 DQEAIAQILDFISA---QTLTPILGIHGGSSMIMADKDESSMFFQFGPSIEQQASVMLNI 160
Query: 146 LDHYEWNCFVFLYDTDRGYSILQAIMEKAGQN---GWHVSAICVENFN-DVSYRQLLEEL 201
++ Y+W F + GY + +N GW + + + + + D ++ +L
Sbjct: 161 MEEYDWYIFSIVTTYFPGYQDFVNKIRSTIENSFVGWELEEVLLLDMSLDDGDSKIQNQL 220
Query: 202 DRRQEKKFVIDCEIERLQNILEQIVSVGKHVKGYHYIIANL 242
+ Q ++ C E I E SVG GY +I+ +L
Sbjct: 221 KKLQSPIILLYCTKEEATYIFEVANSVGLTGYGYTWIVPSL 261
>gi|112789566 taste receptor, type 1, member 2 [Homo sapiens]
Length = 839
Score = 29.3 bits (64), Expect = 7.3
Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 8/85 (9%)
Query: 85 SQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTE---GESQFVLQLRPSLRG- 140
S Y V A+ G + SV T+ +F S + IT S ++ + +F LR +
Sbjct: 129 SNYISRVVAVIGPDNSESVMTVANFLSLFLLPQITYSAISDELRDKVRFPALLRTTPSAD 188
Query: 141 ----ALLSLLDHYEWNCFVFLYDTD 161
A++ L+ H+ WN + L +D
Sbjct: 189 HHIEAMVQLMLHFRWNWIIVLVSSD 213
>gi|87116668 hypothetical protein LOC9870 [Homo sapiens]
Length = 823
Score = 29.3 bits (64), Expect = 7.3
Identities = 17/74 (22%), Positives = 31/74 (41%)
Query: 43 AFRLAIFLHNTSPNASEAPFNLVPHVDNIETANSFAVTNAFCSQYSRGVFAIFGLYDKRS 102
AFR+ +F N P + P L H+ ++E A VT + + V + K
Sbjct: 77 AFRVHLFYKNGQPFPAHRPVGLRVHISHVELAVEIPVTQEVLQEPNSNVVKVAFTVRKAG 136
Query: 103 VHTLTSFCSALHIS 116
+ +T L+++
Sbjct: 137 RYEITVKLGGLNVA 150
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.138 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,415,103
Number of Sequences: 37866
Number of extensions: 656327
Number of successful extensions: 1391
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 21
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1323
Number of HSP's gapped (non-prelim): 24
length of query: 433
length of database: 18,247,518
effective HSP length: 105
effective length of query: 328
effective length of database: 14,271,588
effective search space: 4681080864
effective search space used: 4681080864
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.