Guide to the Human Genome
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Search of human proteins with 116268111

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116268111 short chain dehydrogenase/reductase family 42E,
member 1 [Homo sapiens]
         (393 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116268111 short chain dehydrogenase/reductase family 42E, mem...   799   0.0  
gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo ...   347   1e-95
gi|239756515 PREDICTED: similar to Putative 3-beta-HSD family pr...   346   2e-95
gi|239751020 PREDICTED: hypothetical protein XP_002347673 [Homo ...   346   2e-95
gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo s...   174   2e-43
gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo sap...   174   2e-43
gi|4504509 3 beta-hydroxysteroid dehydrogenase 2 [Homo sapiens]       128   8e-30
gi|19923621 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and s...   123   3e-28
gi|4504507 3 beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]       122   6e-28
gi|218563686 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and ...    69   7e-12
gi|218563684 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and ...    69   7e-12
gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens]                  61   2e-09
gi|56118217 UDP-galactose-4-epimerase [Homo sapiens]                   47   4e-05
gi|56237023 UDP-galactose-4-epimerase [Homo sapiens]                   47   4e-05
gi|189083684 UDP-galactose-4-epimerase [Homo sapiens]                  47   4e-05
gi|42516563 UDP-glucuronate decarboxylase 1 [Homo sapiens]             33   0.34 
gi|46852147 mitochondrial isoleucine tRNA synthetase [Homo sapiens]    29   6.4  
gi|154813204 inhibin beta B subunit preproprotein [Homo sapiens]       29   6.4  
gi|41393563 kinesin family member 1B isoform b [Homo sapiens]          29   6.4  
gi|33519455 methionine adenosyltransferase II, beta isoform 2 [H...    29   6.4  
gi|11034825 methionine adenosyltransferase II, beta isoform 1 [H...    29   6.4  
gi|72384365 zinc finger protein 816A [Homo sapiens]                    29   8.4  

>gi|116268111 short chain dehydrogenase/reductase family 42E, member
           1 [Homo sapiens]
          Length = 393

 Score =  799 bits (2064), Expect = 0.0
 Identities = 393/393 (100%), Positives = 393/393 (100%)

Query: 1   MDPKRSQKESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRH 60
           MDPKRSQKESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRH
Sbjct: 1   MDPKRSQKESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRH 60

Query: 61  LSDVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVY 120
           LSDVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVY
Sbjct: 61  LSDVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVY 120

Query: 121 TSTFNVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRT 180
           TSTFNVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRT
Sbjct: 121 TSTFNVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRT 180

Query: 181 CALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALR 240
           CALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALR
Sbjct: 181 CALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALR 240

Query: 241 ADKGHIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFI 300
           ADKGHIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFI
Sbjct: 241 ADKGHIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFI 300

Query: 301 LGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYKAQPFDLQEAVEWFKAHGHGRSSG 360
           LGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYKAQPFDLQEAVEWFKAHGHGRSSG
Sbjct: 301 LGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYKAQPFDLQEAVEWFKAHGHGRSSG 360

Query: 361 SRDSECFVWDGLLVFLLIIAVLMWLPSSVILSL 393
           SRDSECFVWDGLLVFLLIIAVLMWLPSSVILSL
Sbjct: 361 SRDSECFVWDGLLVFLLIIAVLMWLPSSVILSL 393


>gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo
           sapiens]
          Length = 422

 Score =  347 bits (890), Expect = 1e-95
 Identities = 181/360 (50%), Positives = 234/360 (65%), Gaps = 4/360 (1%)

Query: 3   PKRSQKESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRHLS 62
           P ++ ++ VL+TGG GY GF LG  L ++G  VIL D   P   +    KFIQ D+R   
Sbjct: 28  PTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVILLDRRRPQWELSPETKFIQADVRDEE 87

Query: 63  DVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTS 122
            + +AF+  D  CVFH+ASYGMSG E+L +  I+ +NV GT  ++ VC RRRVPRL+YTS
Sbjct: 88  ALYRAFEGVD--CVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRRRVPRLIYTS 145

Query: 123 TFNVIFGGQVIRNGDE-SLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRTC 181
           T NV FGG+ I  GDE S+PY PL  H DHYSRTK+IA+Q  L AN  PL  G G LRTC
Sbjct: 146 TVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTKAIADQLTLMANGMPLP-GGGTLRTC 204

Query: 182 ALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALRA 241
            LRP GIYGP EQRHLPR+  +I+K LF F +GD ++ + +VHV NLVQAH+LA+EAL  
Sbjct: 205 VLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKARMNWVHVHNLVQAHVLAAEALTT 264

Query: 242 DKGHIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFIL 301
            KG++ASGQ Y+I+DG  VN FE+  PL E LGY+ P  ++P + VY  A + E +H  L
Sbjct: 265 AKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQPWIQVPTSWVYLTAAVMERLHLAL 324

Query: 302 GRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYKAQPFDLQEAVEWFKAHGHGRSSGS 361
             + +  P LTR+EV    VTH F + KA+ +LGY    F   +AVE +      R  GS
Sbjct: 325 RPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAPDKFRFADAVELYVQSTTRRPRGS 384


>gi|239756515 PREDICTED: similar to Putative 3-beta-HSD family
           protein ENSP00000330812 [Homo sapiens]
          Length = 422

 Score =  346 bits (887), Expect = 2e-95
 Identities = 181/360 (50%), Positives = 233/360 (64%), Gaps = 4/360 (1%)

Query: 3   PKRSQKESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRHLS 62
           P ++ ++ VL+TGG GY GF LG  L ++G  VIL D   P   +    KFIQ D+R   
Sbjct: 28  PTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVILLDRRRPQWELSPETKFIQADVRDEE 87

Query: 63  DVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTS 122
            +  AF+  D  CVFH+ASYGMSG E+L +  I+ +NV GT  ++ VC RRRVPRL+YTS
Sbjct: 88  ALYHAFEGVD--CVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRRRVPRLIYTS 145

Query: 123 TFNVIFGGQVIRNGDE-SLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRTC 181
           T NV FGG+ I  GDE S+PY PL  H DHYSRTK+IA+Q  L AN  PL  G G LRTC
Sbjct: 146 TVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTKAIADQLTLMANGMPLP-GGGTLRTC 204

Query: 182 ALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALRA 241
            LRP GIYGP EQRHLPR+  +I+K LF F +GD ++ + +VHV NLVQAH+LA+EAL  
Sbjct: 205 VLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKARMNWVHVHNLVQAHVLAAEALTT 264

Query: 242 DKGHIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFIL 301
            KG++ASGQ Y+I+DG  VN FE+  PL E LGY+ P  ++P + VY  A + E +H  L
Sbjct: 265 AKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQPWIQVPTSWVYLTAAVMERLHLAL 324

Query: 302 GRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYKAQPFDLQEAVEWFKAHGHGRSSGS 361
             + +  P LTR+EV    VTH F + KA+ +LGY    F   +AVE +      R  GS
Sbjct: 325 RPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAPDKFRFADAVELYVQSTTRRPRGS 384


>gi|239751020 PREDICTED: hypothetical protein XP_002347673 [Homo
           sapiens]
          Length = 422

 Score =  346 bits (887), Expect = 2e-95
 Identities = 181/360 (50%), Positives = 233/360 (64%), Gaps = 4/360 (1%)

Query: 3   PKRSQKESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRHLS 62
           P ++ ++ VL+TGG GY GF LG  L ++G  VIL D   P   +    KFIQ D+R   
Sbjct: 28  PTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVILLDRRRPQWELSPETKFIQADVRDEE 87

Query: 63  DVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTS 122
            +  AF+  D  CVFH+ASYGMSG E+L +  I+ +NV GT  ++ VC RRRVPRL+YTS
Sbjct: 88  ALYHAFEGVD--CVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRRRVPRLIYTS 145

Query: 123 TFNVIFGGQVIRNGDE-SLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRTC 181
           T NV FGG+ I  GDE S+PY PL  H DHYSRTK+IA+Q  L AN  PL  G G LRTC
Sbjct: 146 TVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTKAIADQLTLMANGMPLP-GGGTLRTC 204

Query: 182 ALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALRA 241
            LRP GIYGP EQRHLPR+  +I+K LF F +GD ++ + +VHV NLVQAH+LA+EAL  
Sbjct: 205 VLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKARMNWVHVHNLVQAHVLAAEALTT 264

Query: 242 DKGHIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFIL 301
            KG++ASGQ Y+I+DG  VN FE+  PL E LGY+ P  ++P + VY  A + E +H  L
Sbjct: 265 AKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQPWIQVPTSWVYLTAAVMERLHLAL 324

Query: 302 GRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYKAQPFDLQEAVEWFKAHGHGRSSGS 361
             + +  P LTR+EV    VTH F + KA+ +LGY    F   +AVE +      R  GS
Sbjct: 325 RPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAPDKFRFADAVELYVQSTTRRPRGS 384


>gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo
           sapiens]
          Length = 373

 Score =  174 bits (440), Expect = 2e-43
 Identities = 110/333 (33%), Positives = 172/333 (51%), Gaps = 16/333 (4%)

Query: 5   RSQKESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRHLSDV 64
           ++Q +   + GGSG+ G  +   L   G  V +FDI       P+ ++F  GD+    D+
Sbjct: 34  QNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDN-PQ-VRFFLGDLCSRQDL 91

Query: 65  EKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTSTF 124
             A +   V  VFH AS   S     N+ L   VN  GT N+++ C+   V +L+ TS+ 
Sbjct: 92  YPALKG--VNTVFHCASPPPSSN---NKELFYRVNYIGTKNVIETCKEAGVQKLILTSSA 146

Query: 125 NVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRTCALR 184
           +VIF G  I+NG E LPY    +  D+Y+ TK + E+ VL AN    +       T A+R
Sbjct: 147 SVIFEGVDIKNGTEDLPYAMKPI--DYYTETKILQERAVLGANDPEKN-----FLTTAIR 199

Query: 185 PAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALRADKG 244
           P GI+GP + + +P ++     G  KFV G+ ++LV+F  V+N+V  HILA+E L  D  
Sbjct: 200 PHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLSRDS- 258

Query: 245 HIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFILGRL 304
               G+ + I++  P+  + F   ++ GL Y  P   +P  + Y  A L  ++  ++  +
Sbjct: 259 -TLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVAYYLALLLSLLVMVISPV 317

Query: 305 YNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYK 337
              QP  T   V   G  HY+S E+AKK +GY+
Sbjct: 318 IQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQ 350


>gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo
           sapiens]
          Length = 373

 Score =  174 bits (440), Expect = 2e-43
 Identities = 110/333 (33%), Positives = 172/333 (51%), Gaps = 16/333 (4%)

Query: 5   RSQKESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRHLSDV 64
           ++Q +   + GGSG+ G  +   L   G  V +FDI       P+ ++F  GD+    D+
Sbjct: 34  QNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDN-PQ-VRFFLGDLCSRQDL 91

Query: 65  EKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTSTF 124
             A +   V  VFH AS   S     N+ L   VN  GT N+++ C+   V +L+ TS+ 
Sbjct: 92  YPALKG--VNTVFHCASPPPSSN---NKELFYRVNYIGTKNVIETCKEAGVQKLILTSSA 146

Query: 125 NVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRTCALR 184
           +VIF G  I+NG E LPY    +  D+Y+ TK + E+ VL AN    +       T A+R
Sbjct: 147 SVIFEGVDIKNGTEDLPYAMKPI--DYYTETKILQERAVLGANDPEKN-----FLTTAIR 199

Query: 185 PAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALRADKG 244
           P GI+GP + + +P ++     G  KFV G+ ++LV+F  V+N+V  HILA+E L  D  
Sbjct: 200 PHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLSRDS- 258

Query: 245 HIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFILGRL 304
               G+ + I++  P+  + F   ++ GL Y  P   +P  + Y  A L  ++  ++  +
Sbjct: 259 -TLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVAYYLALLLSLLVMVISPV 317

Query: 305 YNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYK 337
              QP  T   V   G  HY+S E+AKK +GY+
Sbjct: 318 IQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQ 350


>gi|4504509 3 beta-hydroxysteroid dehydrogenase 2 [Homo sapiens]
          Length = 372

 Score =  128 bits (322), Expect = 8e-30
 Identities = 107/310 (34%), Positives = 154/310 (49%), Gaps = 26/310 (8%)

Query: 54  IQGDIRHLSDVEKAFQDADVT----CVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQV 109
           ++GDI     +++A QD  V     C+  +  +G++ RE      I  VNV+GT  +L+ 
Sbjct: 58  LEGDILDEPFLKRACQDVSVVIHTACIIDV--FGVTHRES-----IMNVNVKGTQLLLEA 110

Query: 110 CQRRRVPRLVYTSTFNVIFGG---QVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEA 166
           C +  VP  +YTS+  V       ++I+NG E  P    +  P  Y  +K +AE+ VL A
Sbjct: 111 CVQASVPVFIYTSSIEVAGPNSYKEIIQNGHEEEPLE--NTWPTPYPYSKKLAEKAVLAA 168

Query: 167 NATPLDRGDGVLRTCALRPAGIYGPGEQRHLPRIVSYIEK-GLFKFVYGDPRSLVEFVHV 225
           N   L  GD  L TCALRP  IYG G       I   +   G+   V     S V  V+V
Sbjct: 169 NGWNLKNGD-TLYTCALRPTYIYGEGGPFLSASINEALNNNGILSSV--GKFSTVNPVYV 225

Query: 226 DNLVQAHILASEALR-ADKGHIASGQPYFISDGRPVNNFEFFRPLV-EGLGYTFPST-RL 282
            N+  AHILA  ALR   K     GQ Y+ISD  P  +++    ++ +  G    S   L
Sbjct: 226 GNVAWAHILALRALRDPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRWSL 285

Query: 283 PLTLVYCFAFLTEMVHFILGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYK---AQ 339
           PLTL+Y   FL E+V F+L  +Y++QP   R  V  +     FS +KA+++L YK   + 
Sbjct: 286 PLTLMYWIGFLLEVVSFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSW 345

Query: 340 PFDLQEAVEW 349
               Q+ VEW
Sbjct: 346 EEAKQKTVEW 355


>gi|19923621 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
           steroid delta-isomerase 7 isoform a [Homo sapiens]
          Length = 369

 Score =  123 bits (308), Expect = 3e-28
 Identities = 116/356 (32%), Positives = 163/356 (45%), Gaps = 33/356 (9%)

Query: 2   DPKRSQKESVLITGGSGYFGFRLGCALNQNGVHV---ILFDIS-----SPAQTIPEGIKF 53
           D  ++QK   L+TGG G+ G  +   L Q    +    +FD          +T P  +  
Sbjct: 3   DSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVTA 62

Query: 54  IQGDIRHLSDVEKAFQDADVTCVFHIASY-GMSGREQLNRNLIKEVNVRGTDNILQVCQR 112
           IQGD+    +V  A   A V  V H A    + GR   +   I EVNV+GT N+++ C +
Sbjct: 63  IQGDVTQAHEVAAAVAGAHV--VIHTAGLVDVFGRA--SPKTIHEVNVQGTRNVIEACVQ 118

Query: 113 RRVPRLVYTSTFNVI---FGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANAT 169
                LVYTS+  V+     G     G+E  PY  +H HP  Y  +K++AE  VLEAN  
Sbjct: 119 TGTRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHP--YPCSKALAEWLVLEANGR 176

Query: 170 PLDRGDGVLRTCALRPAGIYGPGEQ--RHLPRIVSYIEKGLFKFVYGDPRSLVE-FVHVD 226
            + RG   L TCALRP GIYG G Q  R   R    +   LF+ +   P S+    V+V 
Sbjct: 177 KV-RGGLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAI---PASVEHGRVYVG 232

Query: 227 NLVQAHILASEALRADKGHIASGQPYFISDGRPVN-----NFEFFRPLVEGLGYTFPSTR 281
           N+   H+LA+  L   +  +  GQ YF  DG P       N EF  P   GL        
Sbjct: 233 NVAWMHVLAARELE-QRATLMGGQVYFCYDGSPYRSYEDFNMEFLGPC--GLRLVGARPL 289

Query: 282 LPLTLVYCFAFLTEMVHFILGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYK 337
           LP  L+   A L  ++ ++L  L  + P L    +     T   S +KA++  GY+
Sbjct: 290 LPYWLLVFLAALNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYE 345


>gi|4504507 3 beta-hydroxysteroid dehydrogenase 1 [Homo sapiens]
          Length = 373

 Score =  122 bits (306), Expect = 6e-28
 Identities = 115/364 (31%), Positives = 171/364 (46%), Gaps = 36/364 (9%)

Query: 10  SVLITGGSGYFGFRLGCAL--NQNGVHVILFDISSPAQTIPEGIKF--------IQGDIR 59
           S L+TG  G+ G R+   L   +    + + D +   +   E  K         ++GDI 
Sbjct: 5   SCLVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLEGDIL 64

Query: 60  HLSDVEKAFQDADV----TCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRV 115
               +++A QD  V     C+  +  +G++ RE      I  VNV+GT  +L+ C +  V
Sbjct: 65  DEPFLKRACQDVSVIIHTACIIDV--FGVTHRES-----IMNVNVKGTQLLLEACVQASV 117

Query: 116 PRLVYTSTFNVIFGG---QVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLD 172
           P  +YTS+  V       ++I+NG E  P    +  P  Y  +K +AE+ VL AN   L 
Sbjct: 118 PVFIYTSSIEVAGPNSYKEIIQNGHEEEPLE--NTWPAPYPHSKKLAEKAVLAANGWNLK 175

Query: 173 RGDGVLRTCALRPAGIYGPGEQRHLPRIVSYIEK-GLFKFVYGDPRSLVEFVHVDNLVQA 231
            G G L TCALRP  IYG G +     I   +   G+   V     S V  V+V N+  A
Sbjct: 176 NG-GTLYTCALRPMYIYGEGSRFLSASINEALNNNGILSSV--GKFSTVNPVYVGNVAWA 232

Query: 232 HILASEALR-ADKGHIASGQPYFISDGRPVNNFEFFR-PLVEGLGYTFPST-RLPLTLVY 288
           HILA  AL+   K     GQ Y+ISD  P  +++     L +  G    S    PL+L+Y
Sbjct: 233 HILALRALQDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDSRWSFPLSLMY 292

Query: 289 CFAFLTEMVHFILGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYK---AQPFDLQE 345
              FL E+V F+L  +Y ++P   R  V  +     FS +KA+++L YK   +     Q+
Sbjct: 293 WIGFLLEIVSFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQK 352

Query: 346 AVEW 349
            VEW
Sbjct: 353 TVEW 356


>gi|218563686 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
           steroid delta-isomerase 7 isoform b [Homo sapiens]
          Length = 196

 Score = 68.9 bits (167), Expect = 7e-12
 Identities = 60/178 (33%), Positives = 85/178 (47%), Gaps = 18/178 (10%)

Query: 2   DPKRSQKESVLITGGSGYFGFRLGCALNQNGVHV---ILFDIS-----SPAQTIPEGIKF 53
           D  ++QK   L+TGG G+ G  +   L Q    +    +FD          +T P  +  
Sbjct: 3   DSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVTA 62

Query: 54  IQGDIRHLSDVEKAFQDADVTCVFHIASY-GMSGREQLNRNLIKEVNVRGTDNILQVCQR 112
           IQGD+    +V  A   A V  V H A    + GR   +   I EVNV+GT N+++ C +
Sbjct: 63  IQGDVTQAHEVAAAVAGAHV--VIHTAGLVDVFGRA--SPKTIHEVNVQGTRNVIEACVQ 118

Query: 113 RRVPRLVYTSTFNVI---FGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEAN 167
                LVYTS+  V+     G     G+E  PY  +H HP  Y  +K++AE  VLEAN
Sbjct: 119 TGTRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHP--YPCSKALAEWLVLEAN 174


>gi|218563684 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and
           steroid delta-isomerase 7 isoform b [Homo sapiens]
          Length = 196

 Score = 68.9 bits (167), Expect = 7e-12
 Identities = 60/178 (33%), Positives = 85/178 (47%), Gaps = 18/178 (10%)

Query: 2   DPKRSQKESVLITGGSGYFGFRLGCALNQNGVHV---ILFDIS-----SPAQTIPEGIKF 53
           D  ++QK   L+TGG G+ G  +   L Q    +    +FD          +T P  +  
Sbjct: 3   DSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVTA 62

Query: 54  IQGDIRHLSDVEKAFQDADVTCVFHIASY-GMSGREQLNRNLIKEVNVRGTDNILQVCQR 112
           IQGD+    +V  A   A V  V H A    + GR   +   I EVNV+GT N+++ C +
Sbjct: 63  IQGDVTQAHEVAAAVAGAHV--VIHTAGLVDVFGRA--SPKTIHEVNVQGTRNVIEACVQ 118

Query: 113 RRVPRLVYTSTFNVI---FGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEAN 167
                LVYTS+  V+     G     G+E  PY  +H HP  Y  +K++AE  VLEAN
Sbjct: 119 TGTRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHP--YPCSKALAEWLVLEAN 174


>gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens]
          Length = 350

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 55/238 (23%), Positives = 106/238 (44%), Gaps = 29/238 (12%)

Query: 11  VLITGGSGYFGFRLGCALNQNGVHVILFDISS--------PAQTIP--EGIKFIQGDIRH 60
           VL+TGG+G+    +  +L ++  + ++ ++            +TI   +  KFIQGDI  
Sbjct: 20  VLVTGGAGFIASHMIVSLVEDYPNYMIINLDKLDYCASLKNLETISNKQNYKFIQGDICD 79

Query: 61  LSDVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVY 120
              V+  F+   +  V H A+        +       VNV GT  ++      RV + +Y
Sbjct: 80  SHFVKLLFETEKIDIVLHFAAQTHVDLSFVRAFEFTYVNVYGTHVLVSAAHEARVEKFIY 139

Query: 121 TSTFNVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAE---QKVLEANATPLDRGDGV 177
            ST + ++GG + +  DES P  P     + Y+ +K+ AE   Q   E    P+      
Sbjct: 140 VST-DEVYGGSLDKEFDESSPKQP----TNPYASSKAAAECFVQSYWEQYKFPV------ 188

Query: 178 LRTCALRPAGIYGPGE--QRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHI 233
                 R + +YGP +  ++ +P+ +S ++      ++G       F++  ++V+A +
Sbjct: 189 ---VITRSSNVYGPHQYPEKVIPKFISLLQHNRKCCIHGSGLQTRNFLYATDVVEAFL 243


>gi|56118217 UDP-galactose-4-epimerase [Homo sapiens]
          Length = 348

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 65/276 (23%), Positives = 108/276 (39%), Gaps = 55/276 (19%)

Query: 9   ESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPA----QTIPEGIKFIQG-------- 56
           E VL+TGG+GY G      L + G   ++ D    A     ++PE ++ +Q         
Sbjct: 3   EKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEF 62

Query: 57  ---DIRHLSDVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRR 113
              DI     +++ F+      V H A     G           VN+ GT  +L++ +  
Sbjct: 63  EEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAH 122

Query: 114 RVPRLVYTSTFNVIFGGQVIRNGDESLPYLPL-HLHP-----DHYSRTKSIAEQKVLEAN 167
            V  LV++S+  V    Q          YLPL   HP     + Y ++K   E+ + +  
Sbjct: 123 GVKNLVFSSSATVYGNPQ----------YLPLDEAHPTGGCTNPYGKSKFFIEEMIRD-- 170

Query: 168 ATPLDRGDGVLRTCALR---PAGIYGPG----EQRHLPR----IVSYIEKGLFKF--VYG 214
              L + D       LR   P G +  G    + + +P      VS +  G  +   V+G
Sbjct: 171 ---LCQADKTWNAVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFG 227

Query: 215 ------DPRSLVEFVHVDNLVQAHILASEALRADKG 244
                 D   + +++HV +L + HI A   L+   G
Sbjct: 228 NDYDTEDGTGVRDYIHVVDLAKGHIAALRKLKEQCG 263


>gi|56237023 UDP-galactose-4-epimerase [Homo sapiens]
          Length = 348

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 65/276 (23%), Positives = 108/276 (39%), Gaps = 55/276 (19%)

Query: 9   ESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPA----QTIPEGIKFIQG-------- 56
           E VL+TGG+GY G      L + G   ++ D    A     ++PE ++ +Q         
Sbjct: 3   EKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEF 62

Query: 57  ---DIRHLSDVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRR 113
              DI     +++ F+      V H A     G           VN+ GT  +L++ +  
Sbjct: 63  EEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAH 122

Query: 114 RVPRLVYTSTFNVIFGGQVIRNGDESLPYLPL-HLHP-----DHYSRTKSIAEQKVLEAN 167
            V  LV++S+  V    Q          YLPL   HP     + Y ++K   E+ + +  
Sbjct: 123 GVKNLVFSSSATVYGNPQ----------YLPLDEAHPTGGCTNPYGKSKFFIEEMIRD-- 170

Query: 168 ATPLDRGDGVLRTCALR---PAGIYGPG----EQRHLPR----IVSYIEKGLFKF--VYG 214
              L + D       LR   P G +  G    + + +P      VS +  G  +   V+G
Sbjct: 171 ---LCQADKTWNAVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFG 227

Query: 215 ------DPRSLVEFVHVDNLVQAHILASEALRADKG 244
                 D   + +++HV +L + HI A   L+   G
Sbjct: 228 NDYDTEDGTGVRDYIHVVDLAKGHIAALRKLKEQCG 263


>gi|189083684 UDP-galactose-4-epimerase [Homo sapiens]
          Length = 348

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 65/276 (23%), Positives = 108/276 (39%), Gaps = 55/276 (19%)

Query: 9   ESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPA----QTIPEGIKFIQG-------- 56
           E VL+TGG+GY G      L + G   ++ D    A     ++PE ++ +Q         
Sbjct: 3   EKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEF 62

Query: 57  ---DIRHLSDVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRR 113
              DI     +++ F+      V H A     G           VN+ GT  +L++ +  
Sbjct: 63  EEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAH 122

Query: 114 RVPRLVYTSTFNVIFGGQVIRNGDESLPYLPL-HLHP-----DHYSRTKSIAEQKVLEAN 167
            V  LV++S+  V    Q          YLPL   HP     + Y ++K   E+ + +  
Sbjct: 123 GVKNLVFSSSATVYGNPQ----------YLPLDEAHPTGGCTNPYGKSKFFIEEMIRD-- 170

Query: 168 ATPLDRGDGVLRTCALR---PAGIYGPG----EQRHLPR----IVSYIEKGLFKF--VYG 214
              L + D       LR   P G +  G    + + +P      VS +  G  +   V+G
Sbjct: 171 ---LCQADKTWNAVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFG 227

Query: 215 ------DPRSLVEFVHVDNLVQAHILASEALRADKG 244
                 D   + +++HV +L + HI A   L+   G
Sbjct: 228 NDYDTEDGTGVRDYIHVVDLAKGHIAALRKLKEQCG 263


>gi|42516563 UDP-glucuronate decarboxylase 1 [Homo sapiens]
          Length = 420

 Score = 33.5 bits (75), Expect = 0.34
 Identities = 48/225 (21%), Positives = 85/225 (37%), Gaps = 27/225 (12%)

Query: 8   KESVLITGGSGYFGFRLGCALNQNGVHVILFD--ISSPAQTIPEGIKFIQGDIRHLSDVE 65
           ++ +LITGG+G+ G  L   L  +G  V + D   +   + +   I     ++ +   VE
Sbjct: 88  RKRILITGGAGFVGSHLTDKLMMDGHEVTVVDNFFTGRKRNVEHWIGHENFELINHDVVE 147

Query: 66  KAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTSTFN 125
             + + D   ++H+AS         N     + N  GT N+L + +R    RL+  ST  
Sbjct: 148 PLYIEVDQ--IYHLASPASPPNYMYNPIKTLKTNTIGTLNMLGLAKRVGA-RLLLASTSE 204

Query: 126 VIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAE----------------QKVLEANAT 169
           V    +V    ++   ++        Y   K +AE                 ++      
Sbjct: 205 VYGDPEVHPQSEDYWGHVNPIGPRACYDEGKRVAETMCYAYMKQEGVEVRVARIFNTFGP 264

Query: 170 PLDRGDG------VLRTCALRPAGIYGPGEQRHLPRIVSYIEKGL 208
            +   DG      +L+     P  +YG G Q    + VS +  GL
Sbjct: 265 RMHMNDGRVVSNFILQALQGEPLTVYGSGSQTRAFQYVSDLVNGL 309


>gi|46852147 mitochondrial isoleucine tRNA synthetase [Homo sapiens]
          Length = 1012

 Score = 29.3 bits (64), Expect = 6.4
 Identities = 26/95 (27%), Positives = 36/95 (37%), Gaps = 15/95 (15%)

Query: 122 STFNVI--FGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLR 179
           +TF  I    G  + NG  S P +P    P             +L AN   + +G G++ 
Sbjct: 346 TTFETISTLSGVDLENGTCSHPLIPDKASP-------------LLPANHVTMAKGTGLVH 392

Query: 180 TCALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVYG 214
           T        YG   Q +LP      E G+F  V G
Sbjct: 393 TAPAHGMEDYGVASQHNLPMDCLVDEDGVFTDVAG 427


>gi|154813204 inhibin beta B subunit preproprotein [Homo sapiens]
          Length = 407

 Score = 29.3 bits (64), Expect = 6.4
 Identities = 15/62 (24%), Positives = 28/62 (45%), Gaps = 5/62 (8%)

Query: 88  EQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTSTFNVIFGGQVIRNGDESLPYLPLHL 147
           E + R+++  + +RG  NI        VP+    +    +  G+V  +G   +P+L  H 
Sbjct: 76  EAVKRHILSRLQMRGRPNITHA-----VPKAAMVTALRKLHAGKVREDGRVEIPHLDGHA 130

Query: 148 HP 149
            P
Sbjct: 131 SP 132


>gi|41393563 kinesin family member 1B isoform b [Homo sapiens]
          Length = 1770

 Score = 29.3 bits (64), Expect = 6.4
 Identities = 12/25 (48%), Positives = 16/25 (64%)

Query: 318 KTGVTHYFSLEKAKKELGYKAQPFD 342
           K G THY+SLEK K+ L    + +D
Sbjct: 787 KNGATHYWSLEKLKQRLDLMREMYD 811


>gi|33519455 methionine adenosyltransferase II, beta isoform 2 [Homo
           sapiens]
          Length = 323

 Score = 29.3 bits (64), Expect = 6.4
 Identities = 37/159 (23%), Positives = 64/159 (40%), Gaps = 17/159 (10%)

Query: 11  VLITGGSGYFGFRLGCALNQNGVHVI--LFDISSPAQTIPEGIKFIQGDIRHLSDVEKAF 68
           VL+TG +G  G  +     QN  H +   F  + P        KF Q ++   + V    
Sbjct: 20  VLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARP--------KFEQVNLLDSNAVHHII 71

Query: 69  QDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTSTFNVIF 128
            D     + H A+       +   +   ++NV  + N+ +  +   V   +   + + +F
Sbjct: 72  HDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAK--EAAAVGAFLIYISSDYVF 129

Query: 129 GGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEAN 167
            G      +E +P  PL+L    Y +TK   E+ VLE N
Sbjct: 130 DGTNPPYREEDIP-APLNL----YGKTKLDGEKAVLENN 163


>gi|11034825 methionine adenosyltransferase II, beta isoform 1 [Homo
           sapiens]
          Length = 334

 Score = 29.3 bits (64), Expect = 6.4
 Identities = 37/159 (23%), Positives = 64/159 (40%), Gaps = 17/159 (10%)

Query: 11  VLITGGSGYFGFRLGCALNQNGVHVI--LFDISSPAQTIPEGIKFIQGDIRHLSDVEKAF 68
           VL+TG +G  G  +     QN  H +   F  + P        KF Q ++   + V    
Sbjct: 31  VLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARP--------KFEQVNLLDSNAVHHII 82

Query: 69  QDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTSTFNVIF 128
            D     + H A+       +   +   ++NV  + N+ +  +   V   +   + + +F
Sbjct: 83  HDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAK--EAAAVGAFLIYISSDYVF 140

Query: 129 GGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEAN 167
            G      +E +P  PL+L    Y +TK   E+ VLE N
Sbjct: 141 DGTNPPYREEDIP-APLNL----YGKTKLDGEKAVLENN 174


>gi|72384365 zinc finger protein 816A [Homo sapiens]
          Length = 651

 Score = 28.9 bits (63), Expect = 8.4
 Identities = 23/89 (25%), Positives = 40/89 (44%), Gaps = 1/89 (1%)

Query: 194 QRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALRADKGHIASGQPYF 253
           QR L R V        +FV    +S++EF    + +   ++ +  L+  K H   G   F
Sbjct: 45  QRALYRAVMLENYRNLEFVDSSLKSMMEFSSTRHSITGEVIHTGTLQRHKSH-HIGDFCF 103

Query: 254 ISDGRPVNNFEFFRPLVEGLGYTFPSTRL 282
               + +++FEF    VE  G+  P T++
Sbjct: 104 PEMKKDIHHFEFQWQEVERNGHEAPMTKI 132


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.142    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,228,056
Number of Sequences: 37866
Number of extensions: 691771
Number of successful extensions: 1308
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1255
Number of HSP's gapped (non-prelim): 23
length of query: 393
length of database: 18,247,518
effective HSP length: 104
effective length of query: 289
effective length of database: 14,309,454
effective search space: 4135432206
effective search space used: 4135432206
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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