BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|116268111 short chain dehydrogenase/reductase family 42E, member 1 [Homo sapiens] (393 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|116268111 short chain dehydrogenase/reductase family 42E, mem... 799 0.0 gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo ... 347 1e-95 gi|239756515 PREDICTED: similar to Putative 3-beta-HSD family pr... 346 2e-95 gi|239751020 PREDICTED: hypothetical protein XP_002347673 [Homo ... 346 2e-95 gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo s... 174 2e-43 gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo sap... 174 2e-43 gi|4504509 3 beta-hydroxysteroid dehydrogenase 2 [Homo sapiens] 128 8e-30 gi|19923621 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and s... 123 3e-28 gi|4504507 3 beta-hydroxysteroid dehydrogenase 1 [Homo sapiens] 122 6e-28 gi|218563686 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and ... 69 7e-12 gi|218563684 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and ... 69 7e-12 gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens] 61 2e-09 gi|56118217 UDP-galactose-4-epimerase [Homo sapiens] 47 4e-05 gi|56237023 UDP-galactose-4-epimerase [Homo sapiens] 47 4e-05 gi|189083684 UDP-galactose-4-epimerase [Homo sapiens] 47 4e-05 gi|42516563 UDP-glucuronate decarboxylase 1 [Homo sapiens] 33 0.34 gi|46852147 mitochondrial isoleucine tRNA synthetase [Homo sapiens] 29 6.4 gi|154813204 inhibin beta B subunit preproprotein [Homo sapiens] 29 6.4 gi|41393563 kinesin family member 1B isoform b [Homo sapiens] 29 6.4 gi|33519455 methionine adenosyltransferase II, beta isoform 2 [H... 29 6.4 gi|11034825 methionine adenosyltransferase II, beta isoform 1 [H... 29 6.4 gi|72384365 zinc finger protein 816A [Homo sapiens] 29 8.4 >gi|116268111 short chain dehydrogenase/reductase family 42E, member 1 [Homo sapiens] Length = 393 Score = 799 bits (2064), Expect = 0.0 Identities = 393/393 (100%), Positives = 393/393 (100%) Query: 1 MDPKRSQKESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRH 60 MDPKRSQKESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRH Sbjct: 1 MDPKRSQKESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRH 60 Query: 61 LSDVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVY 120 LSDVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVY Sbjct: 61 LSDVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVY 120 Query: 121 TSTFNVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRT 180 TSTFNVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRT Sbjct: 121 TSTFNVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRT 180 Query: 181 CALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALR 240 CALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALR Sbjct: 181 CALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALR 240 Query: 241 ADKGHIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFI 300 ADKGHIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFI Sbjct: 241 ADKGHIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFI 300 Query: 301 LGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYKAQPFDLQEAVEWFKAHGHGRSSG 360 LGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYKAQPFDLQEAVEWFKAHGHGRSSG Sbjct: 301 LGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYKAQPFDLQEAVEWFKAHGHGRSSG 360 Query: 361 SRDSECFVWDGLLVFLLIIAVLMWLPSSVILSL 393 SRDSECFVWDGLLVFLLIIAVLMWLPSSVILSL Sbjct: 361 SRDSECFVWDGLLVFLLIIAVLMWLPSSVILSL 393 >gi|239745448 PREDICTED: hypothetical protein XP_002343493 [Homo sapiens] Length = 422 Score = 347 bits (890), Expect = 1e-95 Identities = 181/360 (50%), Positives = 234/360 (65%), Gaps = 4/360 (1%) Query: 3 PKRSQKESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRHLS 62 P ++ ++ VL+TGG GY GF LG L ++G VIL D P + KFIQ D+R Sbjct: 28 PTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVILLDRRRPQWELSPETKFIQADVRDEE 87 Query: 63 DVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTS 122 + +AF+ D CVFH+ASYGMSG E+L + I+ +NV GT ++ VC RRRVPRL+YTS Sbjct: 88 ALYRAFEGVD--CVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRRRVPRLIYTS 145 Query: 123 TFNVIFGGQVIRNGDE-SLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRTC 181 T NV FGG+ I GDE S+PY PL H DHYSRTK+IA+Q L AN PL G G LRTC Sbjct: 146 TVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTKAIADQLTLMANGMPLP-GGGTLRTC 204 Query: 182 ALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALRA 241 LRP GIYGP EQRHLPR+ +I+K LF F +GD ++ + +VHV NLVQAH+LA+EAL Sbjct: 205 VLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKARMNWVHVHNLVQAHVLAAEALTT 264 Query: 242 DKGHIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFIL 301 KG++ASGQ Y+I+DG VN FE+ PL E LGY+ P ++P + VY A + E +H L Sbjct: 265 AKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQPWIQVPTSWVYLTAAVMERLHLAL 324 Query: 302 GRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYKAQPFDLQEAVEWFKAHGHGRSSGS 361 + + P LTR+EV VTH F + KA+ +LGY F +AVE + R GS Sbjct: 325 RPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAPDKFRFADAVELYVQSTTRRPRGS 384 >gi|239756515 PREDICTED: similar to Putative 3-beta-HSD family protein ENSP00000330812 [Homo sapiens] Length = 422 Score = 346 bits (887), Expect = 2e-95 Identities = 181/360 (50%), Positives = 233/360 (64%), Gaps = 4/360 (1%) Query: 3 PKRSQKESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRHLS 62 P ++ ++ VL+TGG GY GF LG L ++G VIL D P + KFIQ D+R Sbjct: 28 PTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVILLDRRRPQWELSPETKFIQADVRDEE 87 Query: 63 DVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTS 122 + AF+ D CVFH+ASYGMSG E+L + I+ +NV GT ++ VC RRRVPRL+YTS Sbjct: 88 ALYHAFEGVD--CVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRRRVPRLIYTS 145 Query: 123 TFNVIFGGQVIRNGDE-SLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRTC 181 T NV FGG+ I GDE S+PY PL H DHYSRTK+IA+Q L AN PL G G LRTC Sbjct: 146 TVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTKAIADQLTLMANGMPLP-GGGTLRTC 204 Query: 182 ALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALRA 241 LRP GIYGP EQRHLPR+ +I+K LF F +GD ++ + +VHV NLVQAH+LA+EAL Sbjct: 205 VLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKARMNWVHVHNLVQAHVLAAEALTT 264 Query: 242 DKGHIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFIL 301 KG++ASGQ Y+I+DG VN FE+ PL E LGY+ P ++P + VY A + E +H L Sbjct: 265 AKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQPWIQVPTSWVYLTAAVMERLHLAL 324 Query: 302 GRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYKAQPFDLQEAVEWFKAHGHGRSSGS 361 + + P LTR+EV VTH F + KA+ +LGY F +AVE + R GS Sbjct: 325 RPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAPDKFRFADAVELYVQSTTRRPRGS 384 >gi|239751020 PREDICTED: hypothetical protein XP_002347673 [Homo sapiens] Length = 422 Score = 346 bits (887), Expect = 2e-95 Identities = 181/360 (50%), Positives = 233/360 (64%), Gaps = 4/360 (1%) Query: 3 PKRSQKESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRHLS 62 P ++ ++ VL+TGG GY GF LG L ++G VIL D P + KFIQ D+R Sbjct: 28 PTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVILLDRRRPQWELSPETKFIQADVRDEE 87 Query: 63 DVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTS 122 + AF+ D CVFH+ASYGMSG E+L + I+ +NV GT ++ VC RRRVPRL+YTS Sbjct: 88 ALYHAFEGVD--CVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRRRVPRLIYTS 145 Query: 123 TFNVIFGGQVIRNGDE-SLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRTC 181 T NV FGG+ I GDE S+PY PL H DHYSRTK+IA+Q L AN PL G G LRTC Sbjct: 146 TVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTKAIADQLTLMANGMPLP-GGGTLRTC 204 Query: 182 ALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALRA 241 LRP GIYGP EQRHLPR+ +I+K LF F +GD ++ + +VHV NLVQAH+LA+EAL Sbjct: 205 VLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKARMNWVHVHNLVQAHVLAAEALTT 264 Query: 242 DKGHIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFIL 301 KG++ASGQ Y+I+DG VN FE+ PL E LGY+ P ++P + VY A + E +H L Sbjct: 265 AKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQPWIQVPTSWVYLTAAVMERLHLAL 324 Query: 302 GRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYKAQPFDLQEAVEWFKAHGHGRSSGS 361 + + P LTR+EV VTH F + KA+ +LGY F +AVE + R GS Sbjct: 325 RPICSLPPLLTRSEVRSVAVTHTFQIAKARAQLGYAPDKFRFADAVELYVQSTTRRPRGS 384 >gi|193211614 NAD(P) dependent steroid dehydrogenase-like [Homo sapiens] Length = 373 Score = 174 bits (440), Expect = 2e-43 Identities = 110/333 (33%), Positives = 172/333 (51%), Gaps = 16/333 (4%) Query: 5 RSQKESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRHLSDV 64 ++Q + + GGSG+ G + L G V +FDI P+ ++F GD+ D+ Sbjct: 34 QNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDN-PQ-VRFFLGDLCSRQDL 91 Query: 65 EKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTSTF 124 A + V VFH AS S N+ L VN GT N+++ C+ V +L+ TS+ Sbjct: 92 YPALKG--VNTVFHCASPPPSSN---NKELFYRVNYIGTKNVIETCKEAGVQKLILTSSA 146 Query: 125 NVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRTCALR 184 +VIF G I+NG E LPY + D+Y+ TK + E+ VL AN + T A+R Sbjct: 147 SVIFEGVDIKNGTEDLPYAMKPI--DYYTETKILQERAVLGANDPEKN-----FLTTAIR 199 Query: 185 PAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALRADKG 244 P GI+GP + + +P ++ G KFV G+ ++LV+F V+N+V HILA+E L D Sbjct: 200 PHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLSRDS- 258 Query: 245 HIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFILGRL 304 G+ + I++ P+ + F ++ GL Y P +P + Y A L ++ ++ + Sbjct: 259 -TLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVAYYLALLLSLLVMVISPV 317 Query: 305 YNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYK 337 QP T V G HY+S E+AKK +GY+ Sbjct: 318 IQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQ 350 >gi|8393516 NAD(P) dependent steroid dehydrogenase-like [Homo sapiens] Length = 373 Score = 174 bits (440), Expect = 2e-43 Identities = 110/333 (33%), Positives = 172/333 (51%), Gaps = 16/333 (4%) Query: 5 RSQKESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPAQTIPEGIKFIQGDIRHLSDV 64 ++Q + + GGSG+ G + L G V +FDI P+ ++F GD+ D+ Sbjct: 34 QNQAKRCTVIGGSGFLGQHMVEQLLARGYAVNVFDIQQGFDN-PQ-VRFFLGDLCSRQDL 91 Query: 65 EKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTSTF 124 A + V VFH AS S N+ L VN GT N+++ C+ V +L+ TS+ Sbjct: 92 YPALKG--VNTVFHCASPPPSSN---NKELFYRVNYIGTKNVIETCKEAGVQKLILTSSA 146 Query: 125 NVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLRTCALR 184 +VIF G I+NG E LPY + D+Y+ TK + E+ VL AN + T A+R Sbjct: 147 SVIFEGVDIKNGTEDLPYAMKPI--DYYTETKILQERAVLGANDPEKN-----FLTTAIR 199 Query: 185 PAGIYGPGEQRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALRADKG 244 P GI+GP + + +P ++ G KFV G+ ++LV+F V+N+V HILA+E L D Sbjct: 200 PHGIFGPRDPQLVPILIEAARNGKMKFVIGNGKNLVDFTFVENVVHGHILAAEQLSRDS- 258 Query: 245 HIASGQPYFISDGRPVNNFEFFRPLVEGLGYTFPSTRLPLTLVYCFAFLTEMVHFILGRL 304 G+ + I++ P+ + F ++ GL Y P +P + Y A L ++ ++ + Sbjct: 259 -TLGGKAFHITNDEPIPFWTFLSRILTGLNYEAPKYHIPYWVAYYLALLLSLLVMVISPV 317 Query: 305 YNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYK 337 QP T V G HY+S E+AKK +GY+ Sbjct: 318 IQLQPTFTPMRVALAGTFHYYSCERAKKAMGYQ 350 >gi|4504509 3 beta-hydroxysteroid dehydrogenase 2 [Homo sapiens] Length = 372 Score = 128 bits (322), Expect = 8e-30 Identities = 107/310 (34%), Positives = 154/310 (49%), Gaps = 26/310 (8%) Query: 54 IQGDIRHLSDVEKAFQDADVT----CVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQV 109 ++GDI +++A QD V C+ + +G++ RE I VNV+GT +L+ Sbjct: 58 LEGDILDEPFLKRACQDVSVVIHTACIIDV--FGVTHRES-----IMNVNVKGTQLLLEA 110 Query: 110 CQRRRVPRLVYTSTFNVIFGG---QVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEA 166 C + VP +YTS+ V ++I+NG E P + P Y +K +AE+ VL A Sbjct: 111 CVQASVPVFIYTSSIEVAGPNSYKEIIQNGHEEEPLE--NTWPTPYPYSKKLAEKAVLAA 168 Query: 167 NATPLDRGDGVLRTCALRPAGIYGPGEQRHLPRIVSYIEK-GLFKFVYGDPRSLVEFVHV 225 N L GD L TCALRP IYG G I + G+ V S V V+V Sbjct: 169 NGWNLKNGD-TLYTCALRPTYIYGEGGPFLSASINEALNNNGILSSV--GKFSTVNPVYV 225 Query: 226 DNLVQAHILASEALR-ADKGHIASGQPYFISDGRPVNNFEFFRPLV-EGLGYTFPST-RL 282 N+ AHILA ALR K GQ Y+ISD P +++ ++ + G S L Sbjct: 226 GNVAWAHILALRALRDPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRWSL 285 Query: 283 PLTLVYCFAFLTEMVHFILGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYK---AQ 339 PLTL+Y FL E+V F+L +Y++QP R V + FS +KA+++L YK + Sbjct: 286 PLTLMYWIGFLLEVVSFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSW 345 Query: 340 PFDLQEAVEW 349 Q+ VEW Sbjct: 346 EEAKQKTVEW 355 >gi|19923621 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 isoform a [Homo sapiens] Length = 369 Score = 123 bits (308), Expect = 3e-28 Identities = 116/356 (32%), Positives = 163/356 (45%), Gaps = 33/356 (9%) Query: 2 DPKRSQKESVLITGGSGYFGFRLGCALNQNGVHV---ILFDIS-----SPAQTIPEGIKF 53 D ++QK L+TGG G+ G + L Q + +FD +T P + Sbjct: 3 DSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVTA 62 Query: 54 IQGDIRHLSDVEKAFQDADVTCVFHIASY-GMSGREQLNRNLIKEVNVRGTDNILQVCQR 112 IQGD+ +V A A V V H A + GR + I EVNV+GT N+++ C + Sbjct: 63 IQGDVTQAHEVAAAVAGAHV--VIHTAGLVDVFGRA--SPKTIHEVNVQGTRNVIEACVQ 118 Query: 113 RRVPRLVYTSTFNVI---FGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANAT 169 LVYTS+ V+ G G+E PY +H HP Y +K++AE VLEAN Sbjct: 119 TGTRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHP--YPCSKALAEWLVLEANGR 176 Query: 170 PLDRGDGVLRTCALRPAGIYGPGEQ--RHLPRIVSYIEKGLFKFVYGDPRSLVE-FVHVD 226 + RG L TCALRP GIYG G Q R R + LF+ + P S+ V+V Sbjct: 177 KV-RGGLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAI---PASVEHGRVYVG 232 Query: 227 NLVQAHILASEALRADKGHIASGQPYFISDGRPVN-----NFEFFRPLVEGLGYTFPSTR 281 N+ H+LA+ L + + GQ YF DG P N EF P GL Sbjct: 233 NVAWMHVLAARELE-QRATLMGGQVYFCYDGSPYRSYEDFNMEFLGPC--GLRLVGARPL 289 Query: 282 LPLTLVYCFAFLTEMVHFILGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYK 337 LP L+ A L ++ ++L L + P L + T S +KA++ GY+ Sbjct: 290 LPYWLLVFLAALNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYE 345 >gi|4504507 3 beta-hydroxysteroid dehydrogenase 1 [Homo sapiens] Length = 373 Score = 122 bits (306), Expect = 6e-28 Identities = 115/364 (31%), Positives = 171/364 (46%), Gaps = 36/364 (9%) Query: 10 SVLITGGSGYFGFRLGCAL--NQNGVHVILFDISSPAQTIPEGIKF--------IQGDIR 59 S L+TG G+ G R+ L + + + D + + E K ++GDI Sbjct: 5 SCLVTGAGGFLGQRIIRLLVKEKELKEIRVLDKAFGPELREEFSKLQNKTKLTVLEGDIL 64 Query: 60 HLSDVEKAFQDADV----TCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRV 115 +++A QD V C+ + +G++ RE I VNV+GT +L+ C + V Sbjct: 65 DEPFLKRACQDVSVIIHTACIIDV--FGVTHRES-----IMNVNVKGTQLLLEACVQASV 117 Query: 116 PRLVYTSTFNVIFGG---QVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLD 172 P +YTS+ V ++I+NG E P + P Y +K +AE+ VL AN L Sbjct: 118 PVFIYTSSIEVAGPNSYKEIIQNGHEEEPLE--NTWPAPYPHSKKLAEKAVLAANGWNLK 175 Query: 173 RGDGVLRTCALRPAGIYGPGEQRHLPRIVSYIEK-GLFKFVYGDPRSLVEFVHVDNLVQA 231 G G L TCALRP IYG G + I + G+ V S V V+V N+ A Sbjct: 176 NG-GTLYTCALRPMYIYGEGSRFLSASINEALNNNGILSSV--GKFSTVNPVYVGNVAWA 232 Query: 232 HILASEALR-ADKGHIASGQPYFISDGRPVNNFEFFR-PLVEGLGYTFPST-RLPLTLVY 288 HILA AL+ K GQ Y+ISD P +++ L + G S PL+L+Y Sbjct: 233 HILALRALQDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRLDSRWSFPLSLMY 292 Query: 289 CFAFLTEMVHFILGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYK---AQPFDLQE 345 FL E+V F+L +Y ++P R V + FS +KA+++L YK + Q+ Sbjct: 293 WIGFLLEIVSFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQK 352 Query: 346 AVEW 349 VEW Sbjct: 353 TVEW 356 >gi|218563686 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 isoform b [Homo sapiens] Length = 196 Score = 68.9 bits (167), Expect = 7e-12 Identities = 60/178 (33%), Positives = 85/178 (47%), Gaps = 18/178 (10%) Query: 2 DPKRSQKESVLITGGSGYFGFRLGCALNQNGVHV---ILFDIS-----SPAQTIPEGIKF 53 D ++QK L+TGG G+ G + L Q + +FD +T P + Sbjct: 3 DSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVTA 62 Query: 54 IQGDIRHLSDVEKAFQDADVTCVFHIASY-GMSGREQLNRNLIKEVNVRGTDNILQVCQR 112 IQGD+ +V A A V V H A + GR + I EVNV+GT N+++ C + Sbjct: 63 IQGDVTQAHEVAAAVAGAHV--VIHTAGLVDVFGRA--SPKTIHEVNVQGTRNVIEACVQ 118 Query: 113 RRVPRLVYTSTFNVI---FGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEAN 167 LVYTS+ V+ G G+E PY +H HP Y +K++AE VLEAN Sbjct: 119 TGTRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHP--YPCSKALAEWLVLEAN 174 >gi|218563684 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 isoform b [Homo sapiens] Length = 196 Score = 68.9 bits (167), Expect = 7e-12 Identities = 60/178 (33%), Positives = 85/178 (47%), Gaps = 18/178 (10%) Query: 2 DPKRSQKESVLITGGSGYFGFRLGCALNQNGVHV---ILFDIS-----SPAQTIPEGIKF 53 D ++QK L+TGG G+ G + L Q + +FD +T P + Sbjct: 3 DSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRVTA 62 Query: 54 IQGDIRHLSDVEKAFQDADVTCVFHIASY-GMSGREQLNRNLIKEVNVRGTDNILQVCQR 112 IQGD+ +V A A V V H A + GR + I EVNV+GT N+++ C + Sbjct: 63 IQGDVTQAHEVAAAVAGAHV--VIHTAGLVDVFGRA--SPKTIHEVNVQGTRNVIEACVQ 118 Query: 113 RRVPRLVYTSTFNVI---FGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEAN 167 LVYTS+ V+ G G+E PY +H HP Y +K++AE VLEAN Sbjct: 119 TGTRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHP--YPCSKALAEWLVLEAN 174 >gi|7657641 TDP-glucose 4,6-dehydratase [Homo sapiens] Length = 350 Score = 60.8 bits (146), Expect = 2e-09 Identities = 55/238 (23%), Positives = 106/238 (44%), Gaps = 29/238 (12%) Query: 11 VLITGGSGYFGFRLGCALNQNGVHVILFDISS--------PAQTIP--EGIKFIQGDIRH 60 VL+TGG+G+ + +L ++ + ++ ++ +TI + KFIQGDI Sbjct: 20 VLVTGGAGFIASHMIVSLVEDYPNYMIINLDKLDYCASLKNLETISNKQNYKFIQGDICD 79 Query: 61 LSDVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVY 120 V+ F+ + V H A+ + VNV GT ++ RV + +Y Sbjct: 80 SHFVKLLFETEKIDIVLHFAAQTHVDLSFVRAFEFTYVNVYGTHVLVSAAHEARVEKFIY 139 Query: 121 TSTFNVIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAE---QKVLEANATPLDRGDGV 177 ST + ++GG + + DES P P + Y+ +K+ AE Q E P+ Sbjct: 140 VST-DEVYGGSLDKEFDESSPKQP----TNPYASSKAAAECFVQSYWEQYKFPV------ 188 Query: 178 LRTCALRPAGIYGPGE--QRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHI 233 R + +YGP + ++ +P+ +S ++ ++G F++ ++V+A + Sbjct: 189 ---VITRSSNVYGPHQYPEKVIPKFISLLQHNRKCCIHGSGLQTRNFLYATDVVEAFL 243 >gi|56118217 UDP-galactose-4-epimerase [Homo sapiens] Length = 348 Score = 46.6 bits (109), Expect = 4e-05 Identities = 65/276 (23%), Positives = 108/276 (39%), Gaps = 55/276 (19%) Query: 9 ESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPA----QTIPEGIKFIQG-------- 56 E VL+TGG+GY G L + G ++ D A ++PE ++ +Q Sbjct: 3 EKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEF 62 Query: 57 ---DIRHLSDVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRR 113 DI +++ F+ V H A G VN+ GT +L++ + Sbjct: 63 EEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAH 122 Query: 114 RVPRLVYTSTFNVIFGGQVIRNGDESLPYLPL-HLHP-----DHYSRTKSIAEQKVLEAN 167 V LV++S+ V Q YLPL HP + Y ++K E+ + + Sbjct: 123 GVKNLVFSSSATVYGNPQ----------YLPLDEAHPTGGCTNPYGKSKFFIEEMIRD-- 170 Query: 168 ATPLDRGDGVLRTCALR---PAGIYGPG----EQRHLPR----IVSYIEKGLFKF--VYG 214 L + D LR P G + G + + +P VS + G + V+G Sbjct: 171 ---LCQADKTWNAVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFG 227 Query: 215 ------DPRSLVEFVHVDNLVQAHILASEALRADKG 244 D + +++HV +L + HI A L+ G Sbjct: 228 NDYDTEDGTGVRDYIHVVDLAKGHIAALRKLKEQCG 263 >gi|56237023 UDP-galactose-4-epimerase [Homo sapiens] Length = 348 Score = 46.6 bits (109), Expect = 4e-05 Identities = 65/276 (23%), Positives = 108/276 (39%), Gaps = 55/276 (19%) Query: 9 ESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPA----QTIPEGIKFIQG-------- 56 E VL+TGG+GY G L + G ++ D A ++PE ++ +Q Sbjct: 3 EKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEF 62 Query: 57 ---DIRHLSDVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRR 113 DI +++ F+ V H A G VN+ GT +L++ + Sbjct: 63 EEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAH 122 Query: 114 RVPRLVYTSTFNVIFGGQVIRNGDESLPYLPL-HLHP-----DHYSRTKSIAEQKVLEAN 167 V LV++S+ V Q YLPL HP + Y ++K E+ + + Sbjct: 123 GVKNLVFSSSATVYGNPQ----------YLPLDEAHPTGGCTNPYGKSKFFIEEMIRD-- 170 Query: 168 ATPLDRGDGVLRTCALR---PAGIYGPG----EQRHLPR----IVSYIEKGLFKF--VYG 214 L + D LR P G + G + + +P VS + G + V+G Sbjct: 171 ---LCQADKTWNAVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFG 227 Query: 215 ------DPRSLVEFVHVDNLVQAHILASEALRADKG 244 D + +++HV +L + HI A L+ G Sbjct: 228 NDYDTEDGTGVRDYIHVVDLAKGHIAALRKLKEQCG 263 >gi|189083684 UDP-galactose-4-epimerase [Homo sapiens] Length = 348 Score = 46.6 bits (109), Expect = 4e-05 Identities = 65/276 (23%), Positives = 108/276 (39%), Gaps = 55/276 (19%) Query: 9 ESVLITGGSGYFGFRLGCALNQNGVHVILFDISSPA----QTIPEGIKFIQG-------- 56 E VL+TGG+GY G L + G ++ D A ++PE ++ +Q Sbjct: 3 EKVLVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRSVEF 62 Query: 57 ---DIRHLSDVEKAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRR 113 DI +++ F+ V H A G VN+ GT +L++ + Sbjct: 63 EEMDILDQGALQRLFKKYSFMAVIHFAGLKAVGESVQKPLDYYRVNLTGTIQLLEIMKAH 122 Query: 114 RVPRLVYTSTFNVIFGGQVIRNGDESLPYLPL-HLHP-----DHYSRTKSIAEQKVLEAN 167 V LV++S+ V Q YLPL HP + Y ++K E+ + + Sbjct: 123 GVKNLVFSSSATVYGNPQ----------YLPLDEAHPTGGCTNPYGKSKFFIEEMIRD-- 170 Query: 168 ATPLDRGDGVLRTCALR---PAGIYGPG----EQRHLPR----IVSYIEKGLFKF--VYG 214 L + D LR P G + G + + +P VS + G + V+G Sbjct: 171 ---LCQADKTWNAVLLRYFNPTGAHASGCIGEDPQGIPNNLMPYVSQVAIGRREALNVFG 227 Query: 215 ------DPRSLVEFVHVDNLVQAHILASEALRADKG 244 D + +++HV +L + HI A L+ G Sbjct: 228 NDYDTEDGTGVRDYIHVVDLAKGHIAALRKLKEQCG 263 >gi|42516563 UDP-glucuronate decarboxylase 1 [Homo sapiens] Length = 420 Score = 33.5 bits (75), Expect = 0.34 Identities = 48/225 (21%), Positives = 85/225 (37%), Gaps = 27/225 (12%) Query: 8 KESVLITGGSGYFGFRLGCALNQNGVHVILFD--ISSPAQTIPEGIKFIQGDIRHLSDVE 65 ++ +LITGG+G+ G L L +G V + D + + + I ++ + VE Sbjct: 88 RKRILITGGAGFVGSHLTDKLMMDGHEVTVVDNFFTGRKRNVEHWIGHENFELINHDVVE 147 Query: 66 KAFQDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTSTFN 125 + + D ++H+AS N + N GT N+L + +R RL+ ST Sbjct: 148 PLYIEVDQ--IYHLASPASPPNYMYNPIKTLKTNTIGTLNMLGLAKRVGA-RLLLASTSE 204 Query: 126 VIFGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAE----------------QKVLEANAT 169 V +V ++ ++ Y K +AE ++ Sbjct: 205 VYGDPEVHPQSEDYWGHVNPIGPRACYDEGKRVAETMCYAYMKQEGVEVRVARIFNTFGP 264 Query: 170 PLDRGDG------VLRTCALRPAGIYGPGEQRHLPRIVSYIEKGL 208 + DG +L+ P +YG G Q + VS + GL Sbjct: 265 RMHMNDGRVVSNFILQALQGEPLTVYGSGSQTRAFQYVSDLVNGL 309 >gi|46852147 mitochondrial isoleucine tRNA synthetase [Homo sapiens] Length = 1012 Score = 29.3 bits (64), Expect = 6.4 Identities = 26/95 (27%), Positives = 36/95 (37%), Gaps = 15/95 (15%) Query: 122 STFNVI--FGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEANATPLDRGDGVLR 179 +TF I G + NG S P +P P +L AN + +G G++ Sbjct: 346 TTFETISTLSGVDLENGTCSHPLIPDKASP-------------LLPANHVTMAKGTGLVH 392 Query: 180 TCALRPAGIYGPGEQRHLPRIVSYIEKGLFKFVYG 214 T YG Q +LP E G+F V G Sbjct: 393 TAPAHGMEDYGVASQHNLPMDCLVDEDGVFTDVAG 427 >gi|154813204 inhibin beta B subunit preproprotein [Homo sapiens] Length = 407 Score = 29.3 bits (64), Expect = 6.4 Identities = 15/62 (24%), Positives = 28/62 (45%), Gaps = 5/62 (8%) Query: 88 EQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTSTFNVIFGGQVIRNGDESLPYLPLHL 147 E + R+++ + +RG NI VP+ + + G+V +G +P+L H Sbjct: 76 EAVKRHILSRLQMRGRPNITHA-----VPKAAMVTALRKLHAGKVREDGRVEIPHLDGHA 130 Query: 148 HP 149 P Sbjct: 131 SP 132 >gi|41393563 kinesin family member 1B isoform b [Homo sapiens] Length = 1770 Score = 29.3 bits (64), Expect = 6.4 Identities = 12/25 (48%), Positives = 16/25 (64%) Query: 318 KTGVTHYFSLEKAKKELGYKAQPFD 342 K G THY+SLEK K+ L + +D Sbjct: 787 KNGATHYWSLEKLKQRLDLMREMYD 811 >gi|33519455 methionine adenosyltransferase II, beta isoform 2 [Homo sapiens] Length = 323 Score = 29.3 bits (64), Expect = 6.4 Identities = 37/159 (23%), Positives = 64/159 (40%), Gaps = 17/159 (10%) Query: 11 VLITGGSGYFGFRLGCALNQNGVHVI--LFDISSPAQTIPEGIKFIQGDIRHLSDVEKAF 68 VL+TG +G G + QN H + F + P KF Q ++ + V Sbjct: 20 VLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARP--------KFEQVNLLDSNAVHHII 71 Query: 69 QDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTSTFNVIF 128 D + H A+ + + ++NV + N+ + + V + + + +F Sbjct: 72 HDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAK--EAAAVGAFLIYISSDYVF 129 Query: 129 GGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEAN 167 G +E +P PL+L Y +TK E+ VLE N Sbjct: 130 DGTNPPYREEDIP-APLNL----YGKTKLDGEKAVLENN 163 >gi|11034825 methionine adenosyltransferase II, beta isoform 1 [Homo sapiens] Length = 334 Score = 29.3 bits (64), Expect = 6.4 Identities = 37/159 (23%), Positives = 64/159 (40%), Gaps = 17/159 (10%) Query: 11 VLITGGSGYFGFRLGCALNQNGVHVI--LFDISSPAQTIPEGIKFIQGDIRHLSDVEKAF 68 VL+TG +G G + QN H + F + P KF Q ++ + V Sbjct: 31 VLVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARP--------KFEQVNLLDSNAVHHII 82 Query: 69 QDADVTCVFHIASYGMSGREQLNRNLIKEVNVRGTDNILQVCQRRRVPRLVYTSTFNVIF 128 D + H A+ + + ++NV + N+ + + V + + + +F Sbjct: 83 HDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNLAK--EAAAVGAFLIYISSDYVF 140 Query: 129 GGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEAN 167 G +E +P PL+L Y +TK E+ VLE N Sbjct: 141 DGTNPPYREEDIP-APLNL----YGKTKLDGEKAVLENN 174 >gi|72384365 zinc finger protein 816A [Homo sapiens] Length = 651 Score = 28.9 bits (63), Expect = 8.4 Identities = 23/89 (25%), Positives = 40/89 (44%), Gaps = 1/89 (1%) Query: 194 QRHLPRIVSYIEKGLFKFVYGDPRSLVEFVHVDNLVQAHILASEALRADKGHIASGQPYF 253 QR L R V +FV +S++EF + + ++ + L+ K H G F Sbjct: 45 QRALYRAVMLENYRNLEFVDSSLKSMMEFSSTRHSITGEVIHTGTLQRHKSH-HIGDFCF 103 Query: 254 ISDGRPVNNFEFFRPLVEGLGYTFPSTRL 282 + +++FEF VE G+ P T++ Sbjct: 104 PEMKKDIHHFEFQWQEVERNGHEAPMTKI 132 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.324 0.142 0.432 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,228,056 Number of Sequences: 37866 Number of extensions: 691771 Number of successful extensions: 1308 Number of sequences better than 10.0: 22 Number of HSP's better than 10.0 without gapping: 12 Number of HSP's successfully gapped in prelim test: 10 Number of HSP's that attempted gapping in prelim test: 1255 Number of HSP's gapped (non-prelim): 23 length of query: 393 length of database: 18,247,518 effective HSP length: 104 effective length of query: 289 effective length of database: 14,309,454 effective search space: 4135432206 effective search space used: 4135432206 T: 11 A: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.