BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239508897 PREDICTED: similar to hCG1983816 [Homo sapiens] (265 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239749152 PREDICTED: similar to hCG1983816 [Homo sapiens] 542 e-154 gi|239508897 PREDICTED: similar to hCG1983816 [Homo sapiens] 542 e-154 gi|239754606 PREDICTED: similar to hCG1983816 [Homo sapiens] 502 e-142 gi|7705387 GTF2I repeat domain containing 1 isoform 1 [Homo sapi... 389 e-108 gi|15011924 GTF2I repeat domain containing 1 isoform 2 [Homo sap... 350 9e-97 gi|14670354 general transcription factor II, i isoform 3 [Homo s... 131 5e-31 gi|14670352 general transcription factor II, i isoform 2 [Homo s... 131 5e-31 gi|14670350 general transcription factor II, i isoform 1 [Homo s... 131 5e-31 gi|169881252 general transcription factor II, i isoform 4 [Homo ... 131 5e-31 gi|48762700 GTF2I repeat domain containing 2 [Homo sapiens] 88 9e-18 gi|51241788 GTF2I repeat domain containing 2B [Homo sapiens] 88 9e-18 gi|239752592 PREDICTED: hypothetical protein XP_002348308, parti... 38 0.010 gi|239746033 PREDICTED: hypothetical protein XP_002344174 [Homo ... 38 0.010 gi|239757552 PREDICTED: similar to hCG2006635, partial [Homo sap... 36 0.040 gi|122937289 kinesin family member 18B [Homo sapiens] 31 0.98 gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] 30 2.2 gi|34577118 dopey family member 1 [Homo sapiens] 29 4.8 >gi|239749152 PREDICTED: similar to hCG1983816 [Homo sapiens] Length = 265 Score = 542 bits (1397), Expect = e-154 Identities = 265/265 (100%), Positives = 265/265 (100%) Query: 1 MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ 60 MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ Sbjct: 1 MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ 60 Query: 61 GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK 120 GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK Sbjct: 61 GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK 120 Query: 121 TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGSQNLERILAMANKITFTV 180 TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGSQNLERILAMANKITFTV Sbjct: 121 TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGSQNLERILAMANKITFTV 180 Query: 181 TRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQQQQHHISEGRPFAEIC 240 TRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQQQQHHISEGRPFAEIC Sbjct: 181 TRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQQQQHHISEGRPFAEIC 240 Query: 241 NDAKVPGYTEPFTRHLGATWHDGSD 265 NDAKVPGYTEPFTRHLGATWHDGSD Sbjct: 241 NDAKVPGYTEPFTRHLGATWHDGSD 265 >gi|239508897 PREDICTED: similar to hCG1983816 [Homo sapiens] Length = 265 Score = 542 bits (1397), Expect = e-154 Identities = 265/265 (100%), Positives = 265/265 (100%) Query: 1 MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ 60 MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ Sbjct: 1 MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ 60 Query: 61 GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK 120 GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK Sbjct: 61 GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK 120 Query: 121 TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGSQNLERILAMANKITFTV 180 TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGSQNLERILAMANKITFTV Sbjct: 121 TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGSQNLERILAMANKITFTV 180 Query: 181 TRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQQQQHHISEGRPFAEIC 240 TRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQQQQHHISEGRPFAEIC Sbjct: 181 TRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQQQQHHISEGRPFAEIC 240 Query: 241 NDAKVPGYTEPFTRHLGATWHDGSD 265 NDAKVPGYTEPFTRHLGATWHDGSD Sbjct: 241 NDAKVPGYTEPFTRHLGATWHDGSD 265 >gi|239754606 PREDICTED: similar to hCG1983816 [Homo sapiens] Length = 298 Score = 502 bits (1293), Expect = e-142 Identities = 248/250 (99%), Positives = 249/250 (99%) Query: 1 MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ 60 MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ Sbjct: 1 MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ 60 Query: 61 GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK 120 GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK Sbjct: 61 GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK 120 Query: 121 TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGSQNLERILAMANKITFTV 180 TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGSQNLERILAMANKITFTV Sbjct: 121 TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGSQNLERILAMANKITFTV 180 Query: 181 TRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQQQQHHISEGRPFAEIC 240 TRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQQQQHHISEGRPFAEIC Sbjct: 181 TRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQQQQHHISEGRPFAEIC 240 Query: 241 NDAKVPGYTE 250 NDAKVPG +E Sbjct: 241 NDAKVPGESE 250 >gi|7705387 GTF2I repeat domain containing 1 isoform 1 [Homo sapiens] Length = 959 Score = 389 bits (999), Expect = e-108 Identities = 215/296 (72%), Positives = 229/296 (77%), Gaps = 50/296 (16%) Query: 1 MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ 60 MHPEELFVVGLPEGISLRRPNCFGIAKL KILEASNSIQFVIKRP+LLTEGVKEPI+DSQ Sbjct: 596 MHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIMDSQ 655 Query: 61 GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK 120 GTASSLGFSPPALPPERDS DPLV ESLKRQGFQENYDARL RIDIANTLREQVQ+LFNK Sbjct: 656 GTASSLGFSPPALPPERDSGDPLVDESLKRQGFQENYDARLSRIDIANTLREQVQDLFNK 715 Query: 121 TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITF 178 YGEALGIKYPVQVPYK IKSNPGS+IIE LPPGI FRKP FGSQNLERILA+A+KI F Sbjct: 716 KYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKF 775 Query: 179 TVTRPFQGLIRKPDEDDTNRLGE-VILQEQVKELFNEKYSQCLWL--------------- 222 TVTRPFQGLI KPDEDD NRLGE VIL+EQVKELFNEKY + L L Sbjct: 776 TVTRPFQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSP 835 Query: 223 ----------------------------LQQQQH----HISEGRPFAEICNDAKVP 246 L+ ++H I++ +PFAEICNDAKVP Sbjct: 836 DAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFAEICNDAKVP 891 Score = 71.2 bits (173), Expect = 9e-13 Identities = 61/218 (27%), Positives = 88/218 (40%), Gaps = 49/218 (22%) Query: 52 VKEPIVDSQGTASSLGFSPPALPPERDS---RDPLVGESLKRQGFQENYDARLLRIDIAN 108 ++ + D T+ + S P P DS + L + L E D+ Sbjct: 504 IQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGMEMLTDKGLSEDARPEERPVEDSHGDVIR 563 Query: 109 TLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNL 166 LR+QV+ LFN Y +A+GI PV+VPY +P + + LP GI R+P FG L Sbjct: 564 PLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKL 623 Query: 167 ERILAMANKITFTVTRP-------------FQGLIRK--------PDEDDTN-------- 197 +IL +N I F + RP QG P E D+ Sbjct: 624 RKILEASNSIQFVIKRPELLTEGVKEPIMDSQGTASSLGFSPPALPPERDSGDPLVDESL 683 Query: 198 -----------RLGEV----ILQEQVKELFNEKYSQCL 220 RL + L+EQV++LFN+KY + L Sbjct: 684 KRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEAL 721 Score = 65.5 bits (158), Expect = 5e-11 Identities = 38/92 (41%), Positives = 54/92 (58%), Gaps = 2/92 (2%) Query: 95 ENYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPG 154 E +DA + + NTLRE VQ LFN Y EALG+ + V VPY+ I +P ++ I +P Sbjct: 336 EKWDAFIKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDK 395 Query: 155 ILFRKP--FGSQNLERILAMANKITFTVTRPF 184 I F++P +G L+RIL + I F + R F Sbjct: 396 IPFKRPCTYGVPKLKRILEERHSIHFIIKRMF 427 Score = 60.5 bits (145), Expect = 2e-09 Identities = 38/118 (32%), Positives = 60/118 (50%), Gaps = 10/118 (8%) Query: 70 PPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKTYGEALGIK 129 P A P++ R G SL R + D LLR + V+E+F+ Y EALG Sbjct: 96 PEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLR--------KMVEEVFDVLYSEALGRA 147 Query: 130 YPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFTVTRPFQ 185 V +PY+ + PG + ++ LP G+ FR+P + + L IL +++I F + RP + Sbjct: 148 SVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLE 205 Score = 45.8 bits (107), Expect = 4e-05 Identities = 28/79 (35%), Positives = 39/79 (49%), Gaps = 6/79 (7%) Query: 3 PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQGT 62 PE + +VG+P+ I +RP +G+ KL +ILE +SI F+IKR E I Sbjct: 384 PEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRM------FDERIFTGNKF 437 Query: 63 ASSLGFSPPALPPERDSRD 81 PA PPE S + Sbjct: 438 TKDTTKLEPASPPEDTSAE 456 Score = 40.0 bits (92), Expect = 0.002 Identities = 61/231 (26%), Positives = 93/231 (40%), Gaps = 33/231 (14%) Query: 3 PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP--------KLLTEGVKE 54 P L V GLPEG++ RRP + L ILE S+ I+F +KRP K L E Sbjct: 161 PGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLEDGGRDSKALVELNGV 220 Query: 55 PIVDSQGTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQV 114 ++ L P +PP+ P S F Y L + +RE Sbjct: 221 SLIPKGSRDCGLHGQAPKVPPQ---DLPPTATSSSMASFL--YSTALPN----HAIRELK 271 Query: 115 QELFNKTYGEA-LGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGS--QNLERILA 171 QE + + LG+ P+ P K + S + P G P G QN+ Sbjct: 272 QEAPSCPLAPSDLGLSRPMPEP-KATGAQDFSDCCGQKPTG-----PGGPLIQNVHASKR 325 Query: 172 MANKITFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWL 222 + I + + I++ ++ +T L+E V+ LFN +Y++ L L Sbjct: 326 ILFSIVHDKSEKWDAFIKETEDINT-------LRECVQILFNSRYAEALGL 369 >gi|15011924 GTF2I repeat domain containing 1 isoform 2 [Homo sapiens] Length = 944 Score = 350 bits (897), Expect = 9e-97 Identities = 201/296 (67%), Positives = 214/296 (72%), Gaps = 65/296 (21%) Query: 1 MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQ 60 MHPEELFVVGLPEGISLRRPNCFGIAKL KILEASNSIQFVIKRP+LLTEGVKEPIVDSQ Sbjct: 596 MHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIVDSQ 655 Query: 61 GTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNK 120 ERDS DPLV ESLKRQGFQENYDARL RIDIANTLREQVQ+LFNK Sbjct: 656 ---------------ERDSGDPLVDESLKRQGFQENYDARLSRIDIANTLREQVQDLFNK 700 Query: 121 TYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITF 178 YGEALGIKYPVQVPYK IKSNPGS+IIE LPPGI FRKP FGSQNLERILA+A+KI F Sbjct: 701 KYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKF 760 Query: 179 TVTRPFQGLIRKPDEDDTNRLGE-VILQEQVKELFNEKYSQCLWL--------------- 222 TVTRPFQGLI KPDEDD NRLGE VIL+EQVKELFNEKY + L L Sbjct: 761 TVTRPFQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSP 820 Query: 223 ----------------------------LQQQQH----HISEGRPFAEICNDAKVP 246 L+ ++H I++ +PFAEICNDAKVP Sbjct: 821 DAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFAEICNDAKVP 876 Score = 75.1 bits (183), Expect = 6e-14 Identities = 58/203 (28%), Positives = 88/203 (43%), Gaps = 34/203 (16%) Query: 52 VKEPIVDSQGTASSLGFSPPALPPERDS---RDPLVGESLKRQGFQENYDARLLRIDIAN 108 ++ + D T+ + S P P DS + L + L E D+ Sbjct: 504 IQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGMEMLTDKGLSEDARPEERPVEDSHGDVIR 563 Query: 109 TLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNL 166 LR+QV+ LFN Y +A+GI PV+VPY +P + + LP GI R+P FG L Sbjct: 564 PLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKL 623 Query: 167 ERILAMANKITFTVTRP--FQGLIRKP-----------------------DEDDTNRLGE 201 +IL +N I F + RP +++P E+ RL Sbjct: 624 RKILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSGDPLVDESLKRQGFQENYDARLSR 683 Query: 202 V----ILQEQVKELFNEKYSQCL 220 + L+EQV++LFN+KY + L Sbjct: 684 IDIANTLREQVQDLFNKKYGEAL 706 Score = 65.5 bits (158), Expect = 5e-11 Identities = 38/92 (41%), Positives = 54/92 (58%), Gaps = 2/92 (2%) Query: 95 ENYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPG 154 E +DA + + NTLRE VQ LFN Y EALG+ + V VPY+ I +P ++ I +P Sbjct: 336 EKWDAFIKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDK 395 Query: 155 ILFRKP--FGSQNLERILAMANKITFTVTRPF 184 I F++P +G L+RIL + I F + R F Sbjct: 396 IPFKRPCTYGVPKLKRILEERHSIHFIIKRMF 427 Score = 60.5 bits (145), Expect = 2e-09 Identities = 38/118 (32%), Positives = 60/118 (50%), Gaps = 10/118 (8%) Query: 70 PPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKTYGEALGIK 129 P A P++ R G SL R + D LLR + V+E+F+ Y EALG Sbjct: 96 PEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLR--------KMVEEVFDVLYSEALGRA 147 Query: 130 YPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFTVTRPFQ 185 V +PY+ + PG + ++ LP G+ FR+P + + L IL +++I F + RP + Sbjct: 148 SVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLE 205 Score = 45.8 bits (107), Expect = 4e-05 Identities = 28/79 (35%), Positives = 39/79 (49%), Gaps = 6/79 (7%) Query: 3 PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQGT 62 PE + +VG+P+ I +RP +G+ KL +ILE +SI F+IKR E I Sbjct: 384 PEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRM------FDERIFTGNKF 437 Query: 63 ASSLGFSPPALPPERDSRD 81 PA PPE S + Sbjct: 438 TKDTTKLEPASPPEDTSAE 456 Score = 40.0 bits (92), Expect = 0.002 Identities = 61/231 (26%), Positives = 93/231 (40%), Gaps = 33/231 (14%) Query: 3 PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP--------KLLTEGVKE 54 P L V GLPEG++ RRP + L ILE S+ I+F +KRP K L E Sbjct: 161 PGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLEDGGRDSKALVELNGV 220 Query: 55 PIVDSQGTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQV 114 ++ L P +PP+ P S F Y L + +RE Sbjct: 221 SLIPKGSRDCGLHGQAPKVPPQ---DLPPTATSSSMASFL--YSTALPN----HAIRELK 271 Query: 115 QELFNKTYGEA-LGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKPFGS--QNLERILA 171 QE + + LG+ P+ P K + S + P G P G QN+ Sbjct: 272 QEAPSCPLAPSDLGLSRPMPEP-KATGAQDFSDCCGQKPTG-----PGGPLIQNVHASKR 325 Query: 172 MANKITFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWL 222 + I + + I++ ++ +T L+E V+ LFN +Y++ L L Sbjct: 326 ILFSIVHDKSEKWDAFIKETEDINT-------LRECVQILFNSRYAEALGL 369 >gi|14670354 general transcription factor II, i isoform 3 [Homo sapiens] Length = 977 Score = 131 bits (330), Expect = 5e-31 Identities = 74/213 (34%), Positives = 121/213 (56%), Gaps = 15/213 (7%) Query: 3 PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQGT 62 PE+ +V GLPEG+ RRP+ FGI +L KIL I+F+IK+P++ +KE Sbjct: 745 PEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKE-------- 796 Query: 63 ASSLGFSPP----ALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELF 118 S+ SPP + P + + ++ + ++ + RL +++ A LREQV +LF Sbjct: 797 -STSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLF 855 Query: 119 NKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKI 176 ++ +GEA+G+ +PV+VPY+ I NPG ++++ +PPG+ F+ P ++ RIL A I Sbjct: 856 SRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFI 915 Query: 177 TFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVK 209 FTV RPF GL+ D + ++QE + Sbjct: 916 KFTVIRPFPGLVINNQLVDQSESEGPVIQESAE 948 Score = 111 bits (278), Expect = 6e-25 Identities = 68/184 (36%), Positives = 97/184 (52%), Gaps = 37/184 (20%) Query: 2 HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61 HP +L+V GLPE I R P+ +GI +L KI++ N I+FVIKRP+LLT E Sbjct: 477 HPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTE------- 529 Query: 62 TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121 V + +E+++ R+ + LR+QV+E+FN Sbjct: 530 ----------------------VTQPRTNTPVKEDWNVRITK------LRKQVEEIFNLK 561 Query: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179 + +ALG+ V+VPY +SNP + +E LP GI FR P FG LERI+ +NKI F Sbjct: 562 FAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFV 621 Query: 180 VTRP 183 V +P Sbjct: 622 VKKP 625 Score = 107 bits (268), Expect = 8e-24 Identities = 78/235 (33%), Positives = 116/235 (49%), Gaps = 48/235 (20%) Query: 2 HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61 H E+L+V GLPEGI RRP+ +GI +L +IL A I+FVIK+ +LL Sbjct: 372 HVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELL-----------NS 420 Query: 62 TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121 T L PA G +E + AR+ + LR+ V +LF K Sbjct: 421 TREDLQLDKPA------------------SGVKEEWYARITK------LRKMVDQLFCKK 456 Query: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179 + EALG VPY+ +++P + +E LP I FR P +G LE+I+ + N+I F Sbjct: 457 FAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFV 516 Query: 180 VTRP----------FQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQ 224 + RP Q P ++D N + L++QV+E+FN K++Q L L + Sbjct: 517 IKRPELLTHSTTEVTQPRTNTPVKEDWN-VRITKLRKQVEEIFNLKFAQALGLTE 570 Score = 101 bits (251), Expect = 8e-22 Identities = 82/286 (28%), Positives = 133/286 (46%), Gaps = 71/286 (24%) Query: 2 HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61 +PE L+V GLPEGI R P FGI +L +I+ SN I+FV+K+P+L+ + P + S+ Sbjct: 582 NPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLP-PGMASKI 640 Query: 62 TASSLGFSPPALPPERDSRDPLVGESL--------------------------KRQGFQE 95 +L P +S+ P + ++ K +G + Sbjct: 641 NTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREF 700 Query: 96 NYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGI 155 +++A +I L+++V+ LFN+ GEALG+K V+VP+ +S P +E LP G+ Sbjct: 701 SFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGV 757 Query: 156 LFRKP--FGSQNLERILAMANKITFTVTRP--FQGLIRKP-------------------- 191 FR+P FG LE+IL KI F + +P F+ I++ Sbjct: 758 PFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTA 817 Query: 192 -------------DEDDTNRLGEV----ILQEQVKELFNEKYSQCL 220 +DD RL +V L+EQV +LF+ K+ + + Sbjct: 818 SGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAI 863 Score = 65.1 bits (157), Expect = 6e-11 Identities = 52/170 (30%), Positives = 84/170 (49%), Gaps = 22/170 (12%) Query: 68 FSPPALPPERDSRD----PLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKTYG 123 +SPP+ P+ + P + KR+ + N++ RI LR+QV+ELF + Y Sbjct: 297 YSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARI---TDLRKQVEELFERKYA 353 Query: 124 EALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFTVT 181 +A+ K PV +PY +S+ + +E LP GI FR+P +G LERIL +I F + Sbjct: 354 QAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIK 413 Query: 182 RPFQGLIRKPDED---DTNRLGE--------VILQEQVKELFNEKYSQCL 220 + L+ ED D G L++ V +LF +K+++ L Sbjct: 414 K--HELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEAL 461 Score = 49.3 bits (116), Expect = 3e-06 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 2/78 (2%) Query: 109 TLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNL 166 TLR+ V++ F YG+ALG V VPY+ + + +++++ LP G+ F+ P + L Sbjct: 111 TLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATL 170 Query: 167 ERILAMANKITFTVTRPF 184 + IL I+F + RPF Sbjct: 171 KWILENKAGISFIIKRPF 188 Score = 38.9 bits (89), Expect = 0.005 Identities = 19/40 (47%), Positives = 25/40 (62%) Query: 8 VVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKL 47 V GLPEG++ + P + +A L ILE I F+IKRP L Sbjct: 150 VQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFL 189 Score = 33.5 bits (75), Expect = 0.20 Identities = 14/45 (31%), Positives = 29/45 (64%) Query: 1 MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP 45 ++P + V G+P G+S + P+ I+ + +IL+++ I+F + RP Sbjct: 878 INPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRP 922 >gi|14670352 general transcription factor II, i isoform 2 [Homo sapiens] Length = 978 Score = 131 bits (330), Expect = 5e-31 Identities = 74/213 (34%), Positives = 121/213 (56%), Gaps = 15/213 (7%) Query: 3 PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQGT 62 PE+ +V GLPEG+ RRP+ FGI +L KIL I+F+IK+P++ +KE Sbjct: 746 PEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKE-------- 797 Query: 63 ASSLGFSPP----ALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELF 118 S+ SPP + P + + ++ + ++ + RL +++ A LREQV +LF Sbjct: 798 -STSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLF 856 Query: 119 NKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKI 176 ++ +GEA+G+ +PV+VPY+ I NPG ++++ +PPG+ F+ P ++ RIL A I Sbjct: 857 SRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFI 916 Query: 177 TFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVK 209 FTV RPF GL+ D + ++QE + Sbjct: 917 KFTVIRPFPGLVINNQLVDQSESEGPVIQESAE 949 Score = 111 bits (278), Expect = 6e-25 Identities = 68/184 (36%), Positives = 97/184 (52%), Gaps = 37/184 (20%) Query: 2 HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61 HP +L+V GLPE I R P+ +GI +L KI++ N I+FVIKRP+LLT E Sbjct: 478 HPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTE------- 530 Query: 62 TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121 V + +E+++ R+ + LR+QV+E+FN Sbjct: 531 ----------------------VTQPRTNTPVKEDWNVRITK------LRKQVEEIFNLK 562 Query: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179 + +ALG+ V+VPY +SNP + +E LP GI FR P FG LERI+ +NKI F Sbjct: 563 FAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFV 622 Query: 180 VTRP 183 V +P Sbjct: 623 VKKP 626 Score = 107 bits (268), Expect = 8e-24 Identities = 78/235 (33%), Positives = 116/235 (49%), Gaps = 48/235 (20%) Query: 2 HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61 H E+L+V GLPEGI RRP+ +GI +L +IL A I+FVIK+ +LL Sbjct: 373 HVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELL-----------NS 421 Query: 62 TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121 T L PA G +E + AR+ + LR+ V +LF K Sbjct: 422 TREDLQLDKPA------------------SGVKEEWYARITK------LRKMVDQLFCKK 457 Query: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179 + EALG VPY+ +++P + +E LP I FR P +G LE+I+ + N+I F Sbjct: 458 FAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFV 517 Query: 180 VTRP----------FQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQ 224 + RP Q P ++D N + L++QV+E+FN K++Q L L + Sbjct: 518 IKRPELLTHSTTEVTQPRTNTPVKEDWN-VRITKLRKQVEEIFNLKFAQALGLTE 571 Score = 101 bits (251), Expect = 8e-22 Identities = 82/286 (28%), Positives = 133/286 (46%), Gaps = 71/286 (24%) Query: 2 HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61 +PE L+V GLPEGI R P FGI +L +I+ SN I+FV+K+P+L+ + P + S+ Sbjct: 583 NPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLP-PGMASKI 641 Query: 62 TASSLGFSPPALPPERDSRDPLVGESL--------------------------KRQGFQE 95 +L P +S+ P + ++ K +G + Sbjct: 642 NTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREF 701 Query: 96 NYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGI 155 +++A +I L+++V+ LFN+ GEALG+K V+VP+ +S P +E LP G+ Sbjct: 702 SFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGV 758 Query: 156 LFRKP--FGSQNLERILAMANKITFTVTRP--FQGLIRKP-------------------- 191 FR+P FG LE+IL KI F + +P F+ I++ Sbjct: 759 PFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTA 818 Query: 192 -------------DEDDTNRLGEV----ILQEQVKELFNEKYSQCL 220 +DD RL +V L+EQV +LF+ K+ + + Sbjct: 819 SGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAI 864 Score = 65.1 bits (157), Expect = 6e-11 Identities = 52/170 (30%), Positives = 84/170 (49%), Gaps = 22/170 (12%) Query: 68 FSPPALPPERDSRD----PLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKTYG 123 +SPP+ P+ + P + KR+ + N++ RI LR+QV+ELF + Y Sbjct: 298 YSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARI---TDLRKQVEELFERKYA 354 Query: 124 EALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFTVT 181 +A+ K PV +PY +S+ + +E LP GI FR+P +G LERIL +I F + Sbjct: 355 QAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIK 414 Query: 182 RPFQGLIRKPDED---DTNRLGE--------VILQEQVKELFNEKYSQCL 220 + L+ ED D G L++ V +LF +K+++ L Sbjct: 415 K--HELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEAL 462 Score = 49.3 bits (116), Expect = 3e-06 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 2/78 (2%) Query: 109 TLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNL 166 TLR+ V++ F YG+ALG V VPY+ + + +++++ LP G+ F+ P + L Sbjct: 111 TLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATL 170 Query: 167 ERILAMANKITFTVTRPF 184 + IL I+F + RPF Sbjct: 171 KWILENKAGISFIIKRPF 188 Score = 38.9 bits (89), Expect = 0.005 Identities = 19/40 (47%), Positives = 25/40 (62%) Query: 8 VVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKL 47 V GLPEG++ + P + +A L ILE I F+IKRP L Sbjct: 150 VQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFL 189 Score = 33.5 bits (75), Expect = 0.20 Identities = 14/45 (31%), Positives = 29/45 (64%) Query: 1 MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP 45 ++P + V G+P G+S + P+ I+ + +IL+++ I+F + RP Sbjct: 879 INPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRP 923 >gi|14670350 general transcription factor II, i isoform 1 [Homo sapiens] Length = 998 Score = 131 bits (330), Expect = 5e-31 Identities = 74/213 (34%), Positives = 121/213 (56%), Gaps = 15/213 (7%) Query: 3 PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQGT 62 PE+ +V GLPEG+ RRP+ FGI +L KIL I+F+IK+P++ +KE Sbjct: 766 PEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKE-------- 817 Query: 63 ASSLGFSPP----ALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELF 118 S+ SPP + P + + ++ + ++ + RL +++ A LREQV +LF Sbjct: 818 -STSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLF 876 Query: 119 NKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKI 176 ++ +GEA+G+ +PV+VPY+ I NPG ++++ +PPG+ F+ P ++ RIL A I Sbjct: 877 SRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFI 936 Query: 177 TFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVK 209 FTV RPF GL+ D + ++QE + Sbjct: 937 KFTVIRPFPGLVINNQLVDQSESEGPVIQESAE 969 Score = 111 bits (278), Expect = 6e-25 Identities = 68/184 (36%), Positives = 97/184 (52%), Gaps = 37/184 (20%) Query: 2 HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61 HP +L+V GLPE I R P+ +GI +L KI++ N I+FVIKRP+LLT E Sbjct: 498 HPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTE------- 550 Query: 62 TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121 V + +E+++ R+ + LR+QV+E+FN Sbjct: 551 ----------------------VTQPRTNTPVKEDWNVRITK------LRKQVEEIFNLK 582 Query: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179 + +ALG+ V+VPY +SNP + +E LP GI FR P FG LERI+ +NKI F Sbjct: 583 FAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFV 642 Query: 180 VTRP 183 V +P Sbjct: 643 VKKP 646 Score = 107 bits (268), Expect = 8e-24 Identities = 78/235 (33%), Positives = 116/235 (49%), Gaps = 48/235 (20%) Query: 2 HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61 H E+L+V GLPEGI RRP+ +GI +L +IL A I+FVIK+ +LL Sbjct: 393 HVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELL-----------NS 441 Query: 62 TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121 T L PA G +E + AR+ + LR+ V +LF K Sbjct: 442 TREDLQLDKPA------------------SGVKEEWYARITK------LRKMVDQLFCKK 477 Query: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179 + EALG VPY+ +++P + +E LP I FR P +G LE+I+ + N+I F Sbjct: 478 FAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFV 537 Query: 180 VTRP----------FQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQ 224 + RP Q P ++D N + L++QV+E+FN K++Q L L + Sbjct: 538 IKRPELLTHSTTEVTQPRTNTPVKEDWN-VRITKLRKQVEEIFNLKFAQALGLTE 591 Score = 101 bits (251), Expect = 8e-22 Identities = 82/286 (28%), Positives = 133/286 (46%), Gaps = 71/286 (24%) Query: 2 HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61 +PE L+V GLPEGI R P FGI +L +I+ SN I+FV+K+P+L+ + P + S+ Sbjct: 603 NPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLP-PGMASKI 661 Query: 62 TASSLGFSPPALPPERDSRDPLVGESL--------------------------KRQGFQE 95 +L P +S+ P + ++ K +G + Sbjct: 662 NTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREF 721 Query: 96 NYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGI 155 +++A +I L+++V+ LFN+ GEALG+K V+VP+ +S P +E LP G+ Sbjct: 722 SFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGV 778 Query: 156 LFRKP--FGSQNLERILAMANKITFTVTRP--FQGLIRKP-------------------- 191 FR+P FG LE+IL KI F + +P F+ I++ Sbjct: 779 PFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTA 838 Query: 192 -------------DEDDTNRLGEV----ILQEQVKELFNEKYSQCL 220 +DD RL +V L+EQV +LF+ K+ + + Sbjct: 839 SGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAI 884 Score = 65.1 bits (157), Expect = 6e-11 Identities = 52/170 (30%), Positives = 84/170 (49%), Gaps = 22/170 (12%) Query: 68 FSPPALPPERDSRD----PLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKTYG 123 +SPP+ P+ + P + KR+ + N++ RI LR+QV+ELF + Y Sbjct: 318 YSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARI---TDLRKQVEELFERKYA 374 Query: 124 EALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFTVT 181 +A+ K PV +PY +S+ + +E LP GI FR+P +G LERIL +I F + Sbjct: 375 QAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIK 434 Query: 182 RPFQGLIRKPDED---DTNRLGE--------VILQEQVKELFNEKYSQCL 220 + L+ ED D G L++ V +LF +K+++ L Sbjct: 435 K--HELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEAL 482 Score = 49.3 bits (116), Expect = 3e-06 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 2/78 (2%) Query: 109 TLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNL 166 TLR+ V++ F YG+ALG V VPY+ + + +++++ LP G+ F+ P + L Sbjct: 111 TLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATL 170 Query: 167 ERILAMANKITFTVTRPF 184 + IL I+F + RPF Sbjct: 171 KWILENKAGISFIIKRPF 188 Score = 38.9 bits (89), Expect = 0.005 Identities = 19/40 (47%), Positives = 25/40 (62%) Query: 8 VVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKL 47 V GLPEG++ + P + +A L ILE I F+IKRP L Sbjct: 150 VQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFL 189 Score = 33.5 bits (75), Expect = 0.20 Identities = 14/45 (31%), Positives = 29/45 (64%) Query: 1 MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP 45 ++P + V G+P G+S + P+ I+ + +IL+++ I+F + RP Sbjct: 899 INPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRP 943 >gi|169881252 general transcription factor II, i isoform 4 [Homo sapiens] Length = 957 Score = 131 bits (330), Expect = 5e-31 Identities = 74/213 (34%), Positives = 121/213 (56%), Gaps = 15/213 (7%) Query: 3 PEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQGT 62 PE+ +V GLPEG+ RRP+ FGI +L KIL I+F+IK+P++ +KE Sbjct: 725 PEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKE-------- 776 Query: 63 ASSLGFSPP----ALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELF 118 S+ SPP + P + + ++ + ++ + RL +++ A LREQV +LF Sbjct: 777 -STSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLF 835 Query: 119 NKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKI 176 ++ +GEA+G+ +PV+VPY+ I NPG ++++ +PPG+ F+ P ++ RIL A I Sbjct: 836 SRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFI 895 Query: 177 TFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVK 209 FTV RPF GL+ D + ++QE + Sbjct: 896 KFTVIRPFPGLVINNQLVDQSESEGPVIQESAE 928 Score = 111 bits (278), Expect = 6e-25 Identities = 68/184 (36%), Positives = 97/184 (52%), Gaps = 37/184 (20%) Query: 2 HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61 HP +L+V GLPE I R P+ +GI +L KI++ N I+FVIKRP+LLT E Sbjct: 457 HPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFVIKRPELLTHSTTE------- 509 Query: 62 TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121 V + +E+++ R+ + LR+QV+E+FN Sbjct: 510 ----------------------VTQPRTNTPVKEDWNVRITK------LRKQVEEIFNLK 541 Query: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179 + +ALG+ V+VPY +SNP + +E LP GI FR P FG LERI+ +NKI F Sbjct: 542 FAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFV 601 Query: 180 VTRP 183 V +P Sbjct: 602 VKKP 605 Score = 107 bits (268), Expect = 8e-24 Identities = 78/235 (33%), Positives = 116/235 (49%), Gaps = 48/235 (20%) Query: 2 HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61 H E+L+V GLPEGI RRP+ +GI +L +IL A I+FVIK+ +LL Sbjct: 352 HVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKHELL-----------NS 400 Query: 62 TASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKT 121 T L PA G +E + AR+ + LR+ V +LF K Sbjct: 401 TREDLQLDKPA------------------SGVKEEWYARITK------LRKMVDQLFCKK 436 Query: 122 YGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFT 179 + EALG VPY+ +++P + +E LP I FR P +G LE+I+ + N+I F Sbjct: 437 FAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKIIQVGNRIKFV 496 Query: 180 VTRP----------FQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQCLWLLQ 224 + RP Q P ++D N + L++QV+E+FN K++Q L L + Sbjct: 497 IKRPELLTHSTTEVTQPRTNTPVKEDWN-VRITKLRKQVEEIFNLKFAQALGLTE 550 Score = 101 bits (251), Expect = 8e-22 Identities = 82/286 (28%), Positives = 133/286 (46%), Gaps = 71/286 (24%) Query: 2 HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTEGVKEPIVDSQG 61 +PE L+V GLPEGI R P FGI +L +I+ SN I+FV+K+P+L+ + P + S+ Sbjct: 562 NPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVVKKPELVISYLP-PGMASKI 620 Query: 62 TASSLGFSPPALPPERDSRDPLVGESL--------------------------KRQGFQE 95 +L P +S+ P + ++ K +G + Sbjct: 621 NTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNNNPQTSAVRTPTQTNGSNVPFKPRGREF 680 Query: 96 NYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGI 155 +++A +I L+++V+ LFN+ GEALG+K V+VP+ +S P +E LP G+ Sbjct: 681 SFEAWNAKI---TDLKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGV 737 Query: 156 LFRKP--FGSQNLERILAMANKITFTVTRP--FQGLIRKP-------------------- 191 FR+P FG LE+IL KI F + +P F+ I++ Sbjct: 738 PFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKESTSSKSPPRKINSSPNVNTTA 797 Query: 192 -------------DEDDTNRLGEV----ILQEQVKELFNEKYSQCL 220 +DD RL +V L+EQV +LF+ K+ + + Sbjct: 798 SGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAI 843 Score = 65.1 bits (157), Expect = 6e-11 Identities = 52/170 (30%), Positives = 84/170 (49%), Gaps = 22/170 (12%) Query: 68 FSPPALPPERDSRD----PLVGESLKRQGFQENYDARLLRIDIANTLREQVQELFNKTYG 123 +SPP+ P+ + P + KR+ + N++ RI LR+QV+ELF + Y Sbjct: 277 YSPPSKRPKANELPQPPVPEPANAGKRKVREFNFEKWNARI---TDLRKQVEELFERKYA 333 Query: 124 EALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLERILAMANKITFTVT 181 +A+ K PV +PY +S+ + +E LP GI FR+P +G LERIL +I F + Sbjct: 334 QAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIK 393 Query: 182 RPFQGLIRKPDED---DTNRLGE--------VILQEQVKELFNEKYSQCL 220 + L+ ED D G L++ V +LF +K+++ L Sbjct: 394 K--HELLNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFCKKFAEAL 441 Score = 49.3 bits (116), Expect = 3e-06 Identities = 27/78 (34%), Positives = 45/78 (57%), Gaps = 2/78 (2%) Query: 109 TLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNL 166 TLR+ V++ F YG+ALG V VPY+ + + +++++ LP G+ F+ P + L Sbjct: 111 TLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATL 170 Query: 167 ERILAMANKITFTVTRPF 184 + IL I+F + RPF Sbjct: 171 KWILENKAGISFIIKRPF 188 Score = 38.9 bits (89), Expect = 0.005 Identities = 19/40 (47%), Positives = 25/40 (62%) Query: 8 VVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKL 47 V GLPEG++ + P + +A L ILE I F+IKRP L Sbjct: 150 VQGLPEGVAFKHPENYDLATLKWILENKAGISFIIKRPFL 189 Score = 33.5 bits (75), Expect = 0.20 Identities = 14/45 (31%), Positives = 29/45 (64%) Query: 1 MHPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP 45 ++P + V G+P G+S + P+ I+ + +IL+++ I+F + RP Sbjct: 858 INPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRP 902 >gi|48762700 GTF2I repeat domain containing 2 [Homo sapiens] Length = 949 Score = 87.8 bits (216), Expect = 9e-18 Identities = 48/134 (35%), Positives = 80/134 (59%), Gaps = 10/134 (7%) Query: 95 ENYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPG 154 +N RL I+ LREQV +LF++ +GEA+G+ +PV+VPY+ I NPG ++I+ +PPG Sbjct: 317 DNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPG 376 Query: 155 ILFRKP--FGSQNLERILAMANKITFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVKELF 212 ++F+ P ++ RIL A I FTV RP GL + + +G+ + +Q +F Sbjct: 377 VVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGL-------ELSNVGKRKI-DQEGRVF 428 Query: 213 NEKYSQCLWLLQQQ 226 EK+ + + ++ Q Sbjct: 429 QEKWERAYFFVEVQ 442 Score = 49.7 bits (117), Expect = 3e-06 Identities = 27/79 (34%), Positives = 45/79 (56%), Gaps = 2/79 (2%) Query: 110 LREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLE 167 LR+ V++ F YG+ALG V VPY+ + + +++++ LP G+ F+ P + L+ Sbjct: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166 Query: 168 RILAMANKITFTVTRPFQG 186 IL I+F + RPF G Sbjct: 167 WILENKAGISFIINRPFLG 185 Score = 37.7 bits (86), Expect = 0.010 Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 9/99 (9%) Query: 8 VVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTE---GVKEPIVDSQ---- 60 V GLPEG++ + P + +A L ILE I F+I RP L E G + D++ Sbjct: 145 VQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIV 204 Query: 61 GTASSLGFSPPALPPERDSRDPLVGE--SLKRQGFQENY 97 + S G P DS L E S+K++ NY Sbjct: 205 SPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNY 243 Score = 32.3 bits (72), Expect = 0.44 Identities = 14/44 (31%), Positives = 26/44 (59%) Query: 2 HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP 45 +P + + G+P G+ + P I+ + +ILEA+ I+F + RP Sbjct: 364 NPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRP 407 >gi|51241788 GTF2I repeat domain containing 2B [Homo sapiens] Length = 949 Score = 87.8 bits (216), Expect = 9e-18 Identities = 48/134 (35%), Positives = 80/134 (59%), Gaps = 10/134 (7%) Query: 95 ENYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPG 154 +N RL I+ LREQV +LF++ +GEA+G+ +PV+VPY+ I NPG ++I+ +PPG Sbjct: 317 DNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPG 376 Query: 155 ILFRKP--FGSQNLERILAMANKITFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVKELF 212 ++F+ P ++ RIL A I FTV RP GL + + +G+ + +Q +F Sbjct: 377 VVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGL-------ELSNVGKRKI-DQEGRVF 428 Query: 213 NEKYSQCLWLLQQQ 226 EK+ + + ++ Q Sbjct: 429 QEKWERAYFFVEVQ 442 Score = 49.7 bits (117), Expect = 3e-06 Identities = 27/79 (34%), Positives = 45/79 (56%), Gaps = 2/79 (2%) Query: 110 LREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLE 167 LR+ V++ F YG+ALG V VPY+ + + +++++ LP G+ F+ P + L+ Sbjct: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166 Query: 168 RILAMANKITFTVTRPFQG 186 IL I+F + RPF G Sbjct: 167 WILENKAGISFIINRPFLG 185 Score = 37.7 bits (86), Expect = 0.010 Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 9/99 (9%) Query: 8 VVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTE---GVKEPIVDSQ---- 60 V GLPEG++ + P + +A L ILE I F+I RP L E G + D++ Sbjct: 145 VQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIV 204 Query: 61 GTASSLGFSPPALPPERDSRDPLVGE--SLKRQGFQENY 97 + S G P DS L E S+K++ NY Sbjct: 205 SPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNY 243 Score = 32.3 bits (72), Expect = 0.44 Identities = 14/44 (31%), Positives = 26/44 (59%) Query: 2 HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP 45 +P + + G+P G+ + P I+ + +ILEA+ I+F + RP Sbjct: 364 NPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRP 407 >gi|239752592 PREDICTED: hypothetical protein XP_002348308, partial [Homo sapiens] Length = 94 Score = 37.7 bits (86), Expect = 0.010 Identities = 18/39 (46%), Positives = 25/39 (64%) Query: 6 LFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKR 44 L V GLPEG++ + P + +A L ILE + I F+IKR Sbjct: 56 LIVQGLPEGVAFKHPENYDLATLEWILEYTAGISFIIKR 94 Score = 34.7 bits (78), Expect = 0.088 Identities = 22/77 (28%), Positives = 39/77 (50%), Gaps = 2/77 (2%) Query: 108 NTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQN 165 NT ++ V++ F + L V VPY+ + + ++I++ LP G+ F+ P + Sbjct: 18 NTRKKTVEDYFCFCCLKTLQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLAT 77 Query: 166 LERILAMANKITFTVTR 182 LE IL I+F + R Sbjct: 78 LEWILEYTAGISFIIKR 94 >gi|239746033 PREDICTED: hypothetical protein XP_002344174 [Homo sapiens] Length = 145 Score = 37.7 bits (86), Expect = 0.010 Identities = 18/39 (46%), Positives = 25/39 (64%) Query: 6 LFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKR 44 L V GLPEG++ + P + +A L ILE + I F+IKR Sbjct: 107 LIVQGLPEGVAFKHPENYDLATLEWILEYTAGISFIIKR 145 Score = 37.0 bits (84), Expect = 0.018 Identities = 23/77 (29%), Positives = 40/77 (51%), Gaps = 2/77 (2%) Query: 108 NTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQN 165 NT ++ V++ F +AL V VPY+ + + ++I++ LP G+ F+ P + Sbjct: 69 NTRKKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLAT 128 Query: 166 LERILAMANKITFTVTR 182 LE IL I+F + R Sbjct: 129 LEWILEYTAGISFIIKR 145 >gi|239757552 PREDICTED: similar to hCG2006635, partial [Homo sapiens] Length = 304 Score = 35.8 bits (81), Expect = 0.040 Identities = 17/38 (44%), Positives = 24/38 (63%) Query: 6 LFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIK 43 L V GLPEG++ + P + +A L ILE + I F+IK Sbjct: 56 LIVQGLPEGVAFKHPENYDLATLEWILEYTAGISFIIK 93 Score = 35.4 bits (80), Expect = 0.052 Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 2/75 (2%) Query: 108 NTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQN 165 NT ++ V++ F +AL V VPY+ + + ++I++ LP G+ F+ P + Sbjct: 18 NTRKKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLAT 77 Query: 166 LERILAMANKITFTV 180 LE IL I+F + Sbjct: 78 LEWILEYTAGISFII 92 >gi|122937289 kinesin family member 18B [Homo sapiens] Length = 855 Score = 31.2 bits (69), Expect = 0.98 Identities = 13/26 (50%), Positives = 19/26 (73%), Gaps = 1/26 (3%) Query: 230 ISEGRPFA-EICNDAKVPGYTEPFTR 254 ++ G P A E+C+++K PGYT P TR Sbjct: 572 LARGAPLAQELCSESKPPGYTGPVTR 597 >gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] Length = 1390 Score = 30.0 bits (66), Expect = 2.2 Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 3/62 (4%) Query: 47 LLTEGVKEPIVDSQGTASSLGFSPPALPPERDSRDPLVGESLKRQGFQENYDARLLRIDI 106 +L + K PI + +L P A PPE S L E +KR QE R LRI + Sbjct: 937 ILKQAAKPPISKKKAVLQALEVLPVAPPPEPRS---LTAEEVKRLEEQEEDTFRELRIFL 993 Query: 107 AN 108 N Sbjct: 994 RN 995 >gi|34577118 dopey family member 1 [Homo sapiens] Length = 2465 Score = 28.9 bits (63), Expect = 4.8 Identities = 16/38 (42%), Positives = 24/38 (63%), Gaps = 3/38 (7%) Query: 182 RPFQGLIRKPDEDDTNRLGEVILQEQVKELFNEKYSQC 219 +PF+ LI D+ + LG VIL++ + E+F YSQC Sbjct: 352 KPFRILISLLDKPE---LGPVILEDVLIEVFRTLYSQC 386 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.138 0.418 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,281,844 Number of Sequences: 37866 Number of extensions: 500544 Number of successful extensions: 1448 Number of sequences better than 10.0: 17 Number of HSP's better than 10.0 without gapping: 15 Number of HSP's successfully gapped in prelim test: 2 Number of HSP's that attempted gapping in prelim test: 1318 Number of HSP's gapped (non-prelim): 86 length of query: 265 length of database: 18,247,518 effective HSP length: 100 effective length of query: 165 effective length of database: 14,460,918 effective search space: 2386051470 effective search space used: 2386051470 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.