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Search of human proteins with 23943882
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23943882 serine/threonine kinase 33 [Homo sapiens]
(514 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23943882 serine/threonine kinase 33 [Homo sapiens] 1023 0.0
gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo... 203 3e-52
gi|9966875 calcium/calmodulin-dependent protein kinase ID isofor... 202 5e-52
gi|23943850 calcium/calmodulin-dependent protein kinase ID isofo... 202 5e-52
gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo s... 202 5e-52
gi|149589021 doublecortin-like kinase 3 [Homo sapiens] 189 4e-48
gi|4758128 doublecortin-like kinase 1 [Homo sapiens] 189 7e-48
gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens] 187 3e-47
gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens] 187 3e-47
gi|27901803 protein serine kinase H1 [Homo sapiens] 183 4e-46
gi|83776596 CaM kinase-like vesicle-associated [Homo sapiens] 179 4e-45
gi|209364621 pregnancy upregulated non-ubiquitously expressed Ca... 179 7e-45
gi|209364619 pregnancy upregulated non-ubiquitously expressed Ca... 179 7e-45
gi|32528295 ribosomal protein S6 kinase, polypeptide 5 isoform a... 175 1e-43
gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo ... 172 5e-43
gi|116256471 SNF1-like kinase [Homo sapiens] 172 5e-43
gi|14916455 protein serine kinase H2 [Homo sapiens] 172 7e-43
gi|26667199 calcium/calmodulin-dependent protein kinase II gamma... 170 3e-42
gi|26667191 calcium/calmodulin-dependent protein kinase II gamma... 170 3e-42
gi|26667211 calcium/calmodulin-dependent protein kinase II gamma... 170 3e-42
gi|26667203 calcium/calmodulin-dependent protein kinase II gamma... 170 3e-42
gi|26667196 calcium/calmodulin-dependent protein kinase II gamma... 170 3e-42
gi|4557511 death-associated protein kinase 3 [Homo sapiens] 170 3e-42
gi|7662170 AMPK-related protein kinase 5 [Homo sapiens] 170 3e-42
gi|116089335 BR serine/threonine kinase 2 [Homo sapiens] 169 6e-42
gi|24308326 BR serine/threonine kinase 1 [Homo sapiens] 168 1e-41
gi|32481209 mitogen-activated protein kinase-activated protein k... 166 5e-41
gi|26051218 calcium/calmodulin-dependent protein kinase II beta ... 166 5e-41
gi|26051204 calcium/calmodulin-dependent protein kinase II beta ... 165 1e-40
gi|26051210 calcium/calmodulin-dependent protein kinase II beta ... 165 1e-40
>gi|23943882 serine/threonine kinase 33 [Homo sapiens]
Length = 514
Score = 1023 bits (2646), Expect = 0.0
Identities = 514/514 (100%), Positives = 514/514 (100%)
Query: 1 MADSGLDKKSTKCPDCSSASQKDVLCVCSSKTRVPPVLVVEMSQTSSIGSAESLISLERK 60
MADSGLDKKSTKCPDCSSASQKDVLCVCSSKTRVPPVLVVEMSQTSSIGSAESLISLERK
Sbjct: 1 MADSGLDKKSTKCPDCSSASQKDVLCVCSSKTRVPPVLVVEMSQTSSIGSAESLISLERK 60
Query: 61 KEKNINRDITSRKDLPSRTSNVERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYTFGR 120
KEKNINRDITSRKDLPSRTSNVERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYTFGR
Sbjct: 61 KEKNINRDITSRKDLPSRTSNVERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYTFGR 120
Query: 121 ILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQ 180
ILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQ
Sbjct: 121 ILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQ 180
Query: 181 VFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLK 240
VFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLK
Sbjct: 181 VFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLK 240
Query: 241 LENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDY 300
LENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDY
Sbjct: 241 LENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDY 300
Query: 301 SQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQ 360
SQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQ
Sbjct: 301 SQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQ 360
Query: 361 LMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPS 420
LMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPS
Sbjct: 361 LMKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPS 420
Query: 421 TEEKLKSYQPWGNVPDANYTSDEEEEKQSTAYEKQFPATSKDNFDMCSSSFTSSKLLPAE 480
TEEKLKSYQPWGNVPDANYTSDEEEEKQSTAYEKQFPATSKDNFDMCSSSFTSSKLLPAE
Sbjct: 421 TEEKLKSYQPWGNVPDANYTSDEEEEKQSTAYEKQFPATSKDNFDMCSSSFTSSKLLPAE 480
Query: 481 IKGEMEKTPVTPSQGTATKYPAKSGALSRTKKKL 514
IKGEMEKTPVTPSQGTATKYPAKSGALSRTKKKL
Sbjct: 481 IKGEMEKTPVTPSQGTATKYPAKSGALSRTKKKL 514
>gi|14196445 calcium/calmodulin-dependent protein kinase IG [Homo
sapiens]
Length = 476
Score = 203 bits (516), Expect = 3e-52
Identities = 110/292 (37%), Positives = 170/292 (58%), Gaps = 13/292 (4%)
Query: 112 IEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVK 171
I + + F +LG G+F V + T +A+K + K A + LE E+ +LK +K
Sbjct: 19 IRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSS--LENEIAVLKKIK 76
Query: 172 HEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHN 231
HE+I+ LE ++E+ YLVM+L GEL + + +G ++E + +IQ + SA+ YLH
Sbjct: 77 HENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHE 136
Query: 232 NDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMA 291
N IVHRDLK EN++ + E N I +TDFGL+ +Q+ ++ CGTP Y+A
Sbjct: 137 NGIVHRDLKPENLLYLTP------EENSKIMITDFGLSKMEQN---GIMSTACGTPGYVA 187
Query: 292 PEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSIS 351
PEV++ YS+ D WSIGV+ Y+LL G PPF +E KLFE I++G FE+ W+ IS
Sbjct: 188 PEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDIS 247
Query: 352 DCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKL--SSVRPTNVLEMMKEW 401
+ AK + L++ DP R T ++ L + W+ GN + P+ L++ K +
Sbjct: 248 ESAKDFICHLLEKDPNERYTCEKALSHPWIDGNTALHRDIYPSVSLQIQKNF 299
>gi|9966875 calcium/calmodulin-dependent protein kinase ID isoform 1
[Homo sapiens]
Length = 357
Score = 202 bits (515), Expect = 5e-52
Identities = 108/273 (39%), Positives = 168/273 (61%), Gaps = 9/273 (3%)
Query: 112 IEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVK 171
I++I+ F LG G+F V+ A +K T +A+K + K KA +E E+ +L+ +K
Sbjct: 19 IKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPK-KALKGKESSIENEIAVLRKIK 77
Query: 172 HEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHN 231
HE+I+ LE ++E+P +YLVM+L GEL + + KG ++E + +I+ + A+ YLH
Sbjct: 78 HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHR 137
Query: 232 NDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMA 291
IVHRDLK EN++ S D+ ++I ++DFGL+ K + + + M A CGTP Y+A
Sbjct: 138 MGIVHRDLKPENLLYYSQ--DEESKI----MISDFGLS-KMEGKGDVMSTA-CGTPGYVA 189
Query: 292 PEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSIS 351
PEV++ YS+ D WSIGV+ Y+LL G PPF ++ KLFE I K E F++ W+ IS
Sbjct: 190 PEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDIS 249
Query: 352 DCAKSVLKQLMKVDPAHRITAKELLDNQWLTGN 384
D AK ++ LM+ DP R T ++ + W+ G+
Sbjct: 250 DSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGD 282
>gi|23943850 calcium/calmodulin-dependent protein kinase ID isoform
2 [Homo sapiens]
Length = 385
Score = 202 bits (515), Expect = 5e-52
Identities = 108/273 (39%), Positives = 168/273 (61%), Gaps = 9/273 (3%)
Query: 112 IEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVK 171
I++I+ F LG G+F V+ A +K T +A+K + K KA +E E+ +L+ +K
Sbjct: 19 IKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPK-KALKGKESSIENEIAVLRKIK 77
Query: 172 HEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHN 231
HE+I+ LE ++E+P +YLVM+L GEL + + KG ++E + +I+ + A+ YLH
Sbjct: 78 HENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHR 137
Query: 232 NDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMA 291
IVHRDLK EN++ S D+ ++I ++DFGL+ K + + + M A CGTP Y+A
Sbjct: 138 MGIVHRDLKPENLLYYSQ--DEESKI----MISDFGLS-KMEGKGDVMSTA-CGTPGYVA 189
Query: 292 PEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSIS 351
PEV++ YS+ D WSIGV+ Y+LL G PPF ++ KLFE I K E F++ W+ IS
Sbjct: 190 PEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDIS 249
Query: 352 DCAKSVLKQLMKVDPAHRITAKELLDNQWLTGN 384
D AK ++ LM+ DP R T ++ + W+ G+
Sbjct: 250 DSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGD 282
>gi|4502553 calcium/calmodulin-dependent protein kinase I [Homo
sapiens]
Length = 370
Score = 202 bits (515), Expect = 5e-52
Identities = 113/290 (38%), Positives = 172/290 (59%), Gaps = 17/290 (5%)
Query: 99 GKVPHIRIENGAAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKE----KAGS 154
G V R + I +IY F +LG G+F VI A DK T+ AIK + KE K GS
Sbjct: 3 GAVEGPRWKQAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGS 62
Query: 155 SAVKLLEREVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENE 214
+E E+ +L +KH +I+ L+ ++E+ +YL+M+L GEL + + KG ++E +
Sbjct: 63 -----MENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERD 117
Query: 215 TRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQS 274
+I + A+ YLH+ IVHRDLK EN++ S +D++++I ++DFGL+ K
Sbjct: 118 ASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYS--LDEDSKI----MISDFGLS--KME 169
Query: 275 RSEAMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFEL 334
++L CGTP Y+APEV++ YS+ D WSIGV+ Y+LL G PPF ++ KLFE
Sbjct: 170 DPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQ 229
Query: 335 IRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGN 384
I K E F++ W+ ISD AK ++ LM+ DP R T ++ L + W+ G+
Sbjct: 230 ILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIAGD 279
>gi|149589021 doublecortin-like kinase 3 [Homo sapiens]
Length = 648
Score = 189 bits (481), Expect = 4e-48
Identities = 105/336 (31%), Positives = 188/336 (55%), Gaps = 15/336 (4%)
Query: 58 ERKKEKNINRDITSRKDLPSRTSNVERKASQQQWGRGNFTEGKVPHIRIENGAAIEEIYT 117
E+K + R +T R D P++ + ++ + G+ P A +E+ Y
Sbjct: 300 EKKPCMSGGRRMTLRDDQPAKLEKEPKTRPEEN--KPERPSGRKPRPMGIIAANVEKHYE 357
Query: 118 FGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIH 177
GR++G G+F +V E +ET +A+K ++K + +++ E+ I++S+ H +I+
Sbjct: 358 TGRVIGDGNFAVVKECRHRETRQAYAMKIIDKSRLKGKE-DMVDSEILIIQSLSHPNIVK 416
Query: 178 LEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHR 237
L +V+ET ++YL++E + G+L + + F E + +I L A+ ++H+ IVHR
Sbjct: 417 LHEVYETDMEIYLILEYVQGGDLFDAIIESVKFPEPDAALMIMDLCKALVHMHDKSIVHR 476
Query: 238 DLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISA 297
DLK EN++V+ N + + +K+ DFGLA + CGTP Y+APE++S
Sbjct: 477 DLKPENLLVQR-----NEDKSTTLKLADFGLA----KHVVRPIFTVCGTPTYVAPEILSE 527
Query: 298 HDYSQQCDIWSIGVVMYMLLRGEPPFLA--SSEEKLFELIRKGELHFENAVWNSISDCAK 355
Y + D+W+ GV++Y+LL G PPF + +++LF +I+ G F W++ISD AK
Sbjct: 528 KGYGLEVDMWAAGVILYILLCGFPPFRSPERDQDELFNIIQLGHFEFLPPYWDNISDAAK 587
Query: 356 SVLKQLMKVDPAHRITAKELLDNQWL-TGNKLSSVR 390
++ +L+ VDP R TA ++L + W+ T K ++V+
Sbjct: 588 DLVSRLLVVDPKKRYTAHQVLQHPWIETAGKTNTVK 623
>gi|4758128 doublecortin-like kinase 1 [Homo sapiens]
Length = 729
Score = 189 bits (479), Expect = 7e-48
Identities = 100/279 (35%), Positives = 170/279 (60%), Gaps = 12/279 (4%)
Query: 110 AAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKS 169
A I E Y GR +G G+F +V E ++ T ++A+K + K K +++ EV+IL+
Sbjct: 384 ATITERYKVGRTIGDGNFAVVKECVERSTAREYALKIIKKSKCRGKE-HMIQNEVSILRR 442
Query: 170 VKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYL 229
VKH +I+ L + + P ++YLVMEL + G+L + + ++E + ++ +LASAI YL
Sbjct: 443 VKHPNIVLLIEEMDVPTELYLVMELVKGGDLFDAITSTNKYTERDASGMLYNLASAIKYL 502
Query: 230 HNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIY 289
H+ +IVHRD+K EN+ L+ ++ + + ++K+ DFGLA + + L CGTP Y
Sbjct: 503 HSLNIVHRDIKPENL-----LVYEHQDGSKSLKLGDFGLA----TIVDGPLYTVCGTPTY 553
Query: 290 MAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLAS--SEEKLFELIRKGELHFENAVW 347
+APE+I+ Y + DIW+ GV+ Y+LL G PPF S +E LF+ I G++ F + W
Sbjct: 554 VAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGQVDFPSPYW 613
Query: 348 NSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKL 386
+++SD AK ++ ++ VD R +A ++L++ W+ + L
Sbjct: 614 DNVSDSAKELITMMLLVDVDQRFSAVQVLEHPWVNDDGL 652
>gi|156713430 doublecortin-like kinase 2 isoform b [Homo sapiens]
Length = 765
Score = 187 bits (474), Expect = 3e-47
Identities = 107/312 (34%), Positives = 181/312 (58%), Gaps = 13/312 (4%)
Query: 105 RIENGAAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREV 164
R + + E Y G+++G G+F +V E D+ T ++A+K ++K K L+E EV
Sbjct: 382 RCSESSTLLEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKE-HLIENEV 440
Query: 165 NILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLAS 224
+IL+ VKH +II L + ET +++LVMEL + G+L + + ++E + ++ +LA+
Sbjct: 441 SILRRVKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLAN 500
Query: 225 AIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATC 284
A+ YLH IVHRD+K EN+ L+ + + ++K+ DFGLA + E L C
Sbjct: 501 ALRYLHGLSIVHRDIKPENL-----LVCEYPDGTKSLKLGDFGLA----TVVEGPLYTVC 551
Query: 285 GTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASS--EEKLFELIRKGELHF 342
GTP Y+APE+I+ Y + DIW+ GV+ Y+LL G PPF + + +E LF+ I G+L F
Sbjct: 552 GTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEF 611
Query: 343 ENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGN-KLSSVRPTNVLEMMKEW 401
W++I+D AK ++ Q+++V+ R TA ++L + W++ + + V +K+
Sbjct: 612 PAPYWDNITDSAKELISQMLQVNVEARCTAGQILSHPWVSDDASQENNMQAEVTGKLKQH 671
Query: 402 KNNPESVEENTT 413
NN + +TT
Sbjct: 672 FNNALPKQNSTT 683
>gi|156713428 doublecortin-like kinase 2 isoform a [Homo sapiens]
Length = 766
Score = 187 bits (474), Expect = 3e-47
Identities = 107/312 (34%), Positives = 181/312 (58%), Gaps = 13/312 (4%)
Query: 105 RIENGAAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREV 164
R + + E Y G+++G G+F +V E D+ T ++A+K ++K K L+E EV
Sbjct: 383 RCSESSTLLEKYKIGKVIGDGNFAVVKECIDRSTGKEFALKIIDKAKCCGKE-HLIENEV 441
Query: 165 NILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLAS 224
+IL+ VKH +II L + ET +++LVMEL + G+L + + ++E + ++ +LA+
Sbjct: 442 SILRRVKHPNIIMLVEEMETATELFLVMELVKGGDLFDAITSSTKYTERDGSAMVYNLAN 501
Query: 225 AIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATC 284
A+ YLH IVHRD+K EN+ L+ + + ++K+ DFGLA + E L C
Sbjct: 502 ALRYLHGLSIVHRDIKPENL-----LVCEYPDGTKSLKLGDFGLA----TVVEGPLYTVC 552
Query: 285 GTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASS--EEKLFELIRKGELHF 342
GTP Y+APE+I+ Y + DIW+ GV+ Y+LL G PPF + + +E LF+ I G+L F
Sbjct: 553 GTPTYVAPEIIAETGYGLKVDIWAAGVITYILLCGFPPFRSENNLQEDLFDQILAGKLEF 612
Query: 343 ENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGN-KLSSVRPTNVLEMMKEW 401
W++I+D AK ++ Q+++V+ R TA ++L + W++ + + V +K+
Sbjct: 613 PAPYWDNITDSAKELISQMLQVNVEARCTAGQILSHPWVSDDASQENNMQAEVTGKLKQH 672
Query: 402 KNNPESVEENTT 413
NN + +TT
Sbjct: 673 FNNALPKQNSTT 684
>gi|27901803 protein serine kinase H1 [Homo sapiens]
Length = 424
Score = 183 bits (464), Expect = 4e-46
Identities = 96/274 (35%), Positives = 156/274 (56%), Gaps = 10/274 (3%)
Query: 116 YTFGRILGKGSFGIVIEATDKETETKWAIKKVN-KEKAGSSAVKLLEREVNILKSVKHEH 174
Y ++G+GSF V+ + T +AIK + K + G ++ E E+ +L+ V+H +
Sbjct: 98 YDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGR---EVCESELRVLRRVRHAN 154
Query: 175 IIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDI 234
II L +VFET +++Y+VMEL GEL + + KG F+E + ++Q + + YLH I
Sbjct: 155 IIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGI 214
Query: 235 VHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEV 294
HRDLK EN++ D I +TDFGLA ++ + +++ TCGTP Y+APEV
Sbjct: 215 THRDLKPENLLYYHPGTDSK------IIITDFGLASARKKGDDCLMKTTCGTPEYIAPEV 268
Query: 295 ISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCA 354
+ Y+ D+W++GV+ Y+LL G PF + +L+ I +G+ + W S+S+ A
Sbjct: 269 LVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLA 328
Query: 355 KSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSS 388
K + +L+ VDP R+TA + L + W+ SS
Sbjct: 329 KDFIDRLLTVDPGARMTALQALRHPWVVSMAASS 362
>gi|83776596 CaM kinase-like vesicle-associated [Homo sapiens]
Length = 501
Score = 179 bits (455), Expect = 4e-45
Identities = 101/284 (35%), Positives = 157/284 (55%), Gaps = 19/284 (6%)
Query: 112 IEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVK 171
+ + Y G+++ F + A DK T KK K + G K + E+ ILK VK
Sbjct: 20 VTDRYDLGQVIKTEEFCEIFRAKDKTTGKLHTCKKFQK-RDGRKVRKAAKNEIGILKMVK 78
Query: 172 HEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHN 231
H +I+ L VF T K+ ++ +EL E+ + + +G++SE +T +++ + A+AYLH+
Sbjct: 79 HPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDTSNVVRQVLEAVAYLHS 138
Query: 232 NDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMA 291
IVHR+LKLEN L+ N N I ++DF LA +++ CGTP Y+A
Sbjct: 139 LKIVHRNLKLEN------LVYYNRLKNSKIVISDFHLA----KLENGLIKEPCGTPEYLA 188
Query: 292 PEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEE--------KLFELIRKGELHFE 343
PEV+ Y + D W+IGV+MY+LL G PPF EE LF I G+ F+
Sbjct: 189 PEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDYEFD 248
Query: 344 NAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLS 387
+ W+ IS AK ++ +LM+V+ RITA+E + ++W++GN S
Sbjct: 249 SPYWDDISQAAKDLVTRLMEVEQDQRITAEEAISHEWISGNAAS 292
>gi|209364621 pregnancy upregulated non-ubiquitously expressed CaM
kinase isoform b [Homo sapiens]
Length = 360
Score = 179 bits (453), Expect = 7e-45
Identities = 94/273 (34%), Positives = 157/273 (57%), Gaps = 10/273 (3%)
Query: 112 IEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVK 171
I +Y LG G+F V+ A ++ + A+K + K KA L+E E+ +L+ +
Sbjct: 28 ISSVYEIRERLGSGAFSEVVLAQERGSAHLVALKCIPK-KALRGKEALVENEIAVLRRIS 86
Query: 172 HEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHN 231
H +I+ LE V E+P +YL MEL GEL + + +G ++E + ++ + A++YLH+
Sbjct: 87 HPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHS 146
Query: 232 NDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMA 291
IVHRDLK EN++ + D I V+DFGL+ + ++ ML CGTP Y+A
Sbjct: 147 LGIVHRDLKPENLLYATPFEDSK------IMVSDFGLS---KIQAGNMLGTACGTPGYVA 197
Query: 292 PEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSIS 351
PE++ Y + D+W++GV+ Y+LL G PPF S+ +LF I + F++ W+ IS
Sbjct: 198 PELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDIS 257
Query: 352 DCAKSVLKQLMKVDPAHRITAKELLDNQWLTGN 384
+ AK ++ L++ DP R T ++ L + W++G+
Sbjct: 258 ESAKDFIRHLLERDPQKRFTCQQALRHLWISGD 290
>gi|209364619 pregnancy upregulated non-ubiquitously expressed CaM
kinase isoform a [Homo sapiens]
Length = 426
Score = 179 bits (453), Expect = 7e-45
Identities = 94/273 (34%), Positives = 157/273 (57%), Gaps = 10/273 (3%)
Query: 112 IEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVK 171
I +Y LG G+F V+ A ++ + A+K + K KA L+E E+ +L+ +
Sbjct: 94 ISSVYEIRERLGSGAFSEVVLAQERGSAHLVALKCIPK-KALRGKEALVENEIAVLRRIS 152
Query: 172 HEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHN 231
H +I+ LE V E+P +YL MEL GEL + + +G ++E + ++ + A++YLH+
Sbjct: 153 HPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHS 212
Query: 232 NDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMA 291
IVHRDLK EN++ + D I V+DFGL+ + ++ ML CGTP Y+A
Sbjct: 213 LGIVHRDLKPENLLYATPFEDSK------IMVSDFGLS---KIQAGNMLGTACGTPGYVA 263
Query: 292 PEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSIS 351
PE++ Y + D+W++GV+ Y+LL G PPF S+ +LF I + F++ W+ IS
Sbjct: 264 PELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDIS 323
Query: 352 DCAKSVLKQLMKVDPAHRITAKELLDNQWLTGN 384
+ AK ++ L++ DP R T ++ L + W++G+
Sbjct: 324 ESAKDFIRHLLERDPQKRFTCQQALRHLWISGD 356
>gi|32528295 ribosomal protein S6 kinase, polypeptide 5 isoform a
[Homo sapiens]
Length = 802
Score = 175 bits (443), Expect = 1e-43
Identities = 100/276 (36%), Positives = 163/276 (59%), Gaps = 21/276 (7%)
Query: 122 LGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVK-HEHIIHLEQ 180
LG+GSF I + K++ +A+K ++K ++ ++E+ LK + H +I+ L +
Sbjct: 432 LGEGSFSICRKCVHKKSNQAFAVKIISKRMEANT-----QKEITALKLCEGHPNIVKLHE 486
Query: 181 VFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLK 240
VF +LVMEL GEL E + +K HFSE E +I++ L SA++++H+ +VHRDLK
Sbjct: 487 VFHDQLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLK 546
Query: 241 LENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDY 300
EN+ L D N+ NL IK+ DFG A K ++ L+ C T Y APE+++ + Y
Sbjct: 547 PENL-----LFTDEND-NLEIKIIDFGFARLKPPDNQP-LKTPCFTLHYAAPELLNQNGY 599
Query: 301 SQQCDIWSIGVVMYMLLRGEPPFLA-------SSEEKLFELIRKGELHFENAVWNSISDC 353
+ CD+WS+GV++Y +L G+ PF + +S ++ + I+KG+ FE W ++S
Sbjct: 600 DESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQE 659
Query: 354 AKSVLKQLMKVDPAHRITAKELLDNQWL-TGNKLSS 388
AK +++ L+ VDP R+ L N+WL G++LSS
Sbjct: 660 AKDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSS 695
Score = 114 bits (285), Expect = 2e-25
Identities = 76/261 (29%), Positives = 139/261 (53%), Gaps = 21/261 (8%)
Query: 120 RILGKGSFG---IVIEATDKETETKWAIKKVNK----EKAGSSAVKLLEREVNILKSVKH 172
++LG G++G +V + + +T +A+K + K +KA ++ ER+V L+ ++
Sbjct: 53 KVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQV--LEHIRQ 110
Query: 173 E-HIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHN 231
++ L F+T K++L+++ GEL L ++ F+E+E + + + A+ +LH
Sbjct: 111 SPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHK 170
Query: 232 NDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMA 291
I++RD+KLENI++ S N ++ +TDFGL+ + + + CGT YMA
Sbjct: 171 LGIIYRDIKLENILLDS---------NGHVVLTDFGLSKEFVADETERAYSFCGTIEYMA 221
Query: 292 PEVISAHD--YSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNS 349
P+++ D + + D WS+GV+MY LL G PF E+ I + L E
Sbjct: 222 PDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQE 281
Query: 350 ISDCAKSVLKQLMKVDPAHRI 370
+S AK ++++L+ DP R+
Sbjct: 282 MSALAKDLIQRLLMKDPKKRL 302
>gi|4502557 calcium/calmodulin-dependent protein kinase IV [Homo
sapiens]
Length = 473
Score = 172 bits (437), Expect = 5e-43
Identities = 98/308 (31%), Positives = 170/308 (55%), Gaps = 15/308 (4%)
Query: 97 TEGKVPHIRIE--NGAAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGS 154
T VP I+ N A+ + + LG+G+ IV K T+ +A+K + K +
Sbjct: 25 TASLVPDYWIDGSNRDALSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKK----T 80
Query: 155 SAVKLLEREVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENE 214
K++ E+ +L + H +II L+++FETP ++ LV+EL GEL + + KG++SE +
Sbjct: 81 VDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERD 140
Query: 215 TRWIIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQS 274
++ + A+AYLH N IVHRDLK EN++ + D +K+ DFGL+ K
Sbjct: 141 AADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPD------APLKIADFGLS--KIV 192
Query: 275 RSEAMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFL-ASSEEKLFE 333
+ +++ CGTP Y APE++ Y + D+WS+G++ Y+LL G PF ++ +F
Sbjct: 193 EHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQFMFR 252
Query: 334 LIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTN 393
I E +F + W+ +S AK ++++L+ +DP R+T + L + W+TG + V
Sbjct: 253 RILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWVTGKAANFVHMDT 312
Query: 394 VLEMMKEW 401
+ ++E+
Sbjct: 313 AQKKLQEF 320
>gi|116256471 SNF1-like kinase [Homo sapiens]
Length = 783
Score = 172 bits (437), Expect = 5e-43
Identities = 99/267 (37%), Positives = 153/267 (57%), Gaps = 16/267 (5%)
Query: 116 YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHI 175
Y R LGKG+F +V A + T+T+ AIK ++K + SS ++ + REV ++K + H HI
Sbjct: 27 YDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDKTRLDSSNLEKIYREVQLMKLLNHPHI 86
Query: 176 IHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIV 235
I L QV ET +Y+V E ++GE+ + L GH SENE R + SA+ Y H++ IV
Sbjct: 87 IKLYQVMETKDMLYIVTEFAKNGEMFDYLTSNGHLSENEARKKFWQILSAVEYCHDHHIV 146
Query: 236 HRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVI 295
HRDLK EN+++ N++IK+ DFG +S L CG+P Y APEV
Sbjct: 147 HRDLKTENLLLDG---------NMDIKLADFGFG--NFYKSGEPLSTWCGSPPYAAPEVF 195
Query: 296 SAHDY-SQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCA 354
+Y Q DIWS+GVV+Y+L+ G PF + L + + +G + DC
Sbjct: 196 EGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLRQRVLEGRFRIP---FFMSQDC- 251
Query: 355 KSVLKQLMKVDPAHRITAKELLDNQWL 381
+S++++++ VDPA RIT ++ ++W+
Sbjct: 252 ESLIRRMLVVDPARRITIAQIRQHRWM 278
>gi|14916455 protein serine kinase H2 [Homo sapiens]
Length = 385
Score = 172 bits (436), Expect = 7e-43
Identities = 99/311 (31%), Positives = 169/311 (54%), Gaps = 17/311 (5%)
Query: 116 YTFGRILGKGSFGIVIEATDKETETKWAIKKVN-KEKAGSSAVKLLEREVNILKSVKHEH 174
Y ++G GSF V+ K T+ +AIK + +E+ G A E+++L+ V H +
Sbjct: 63 YDIKALIGTGSFSRVVRVEQKTTKKPFAIKVMETREREGREACV---SELSVLRRVSHRY 119
Query: 175 IIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDI 234
I+ L ++FET ++Y+VMEL GEL + L +G F+E + I+Q +A I YLH I
Sbjct: 120 IVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQI 179
Query: 235 VHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEV 294
HR+LK EN++ + I +TDFGLA + + ++ CGTP Y+APEV
Sbjct: 180 THRNLKPENLLYYHPGEESK------ILITDFGLAYSGKKSGDWTMKTLCGTPEYIAPEV 233
Query: 295 ISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCA 354
+ Y+ D+W++GV+ Y LL G PF S+ +L+ I KG+ ++ W SIS A
Sbjct: 234 LLRKPYTSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLA 293
Query: 355 KSVLKQLMKVDPAHRITAKELLDNQWL----TGNKLSSVR---PTNVLEMMKEWKNNPES 407
K + +L+ ++ HR++A + LD+ W+ G+ + +++ N+++ +P S
Sbjct: 294 KDFIDKLLILEAGHRMSAGQALDHPWVITMAAGSSMKNLQRAISRNLMQRASPHSQSPGS 353
Query: 408 VEENTTEEKNK 418
+ + + +K
Sbjct: 354 AQSSKSHYSHK 364
>gi|26667199 calcium/calmodulin-dependent protein kinase II gamma
isoform 3 [Homo sapiens]
Length = 518
Score = 170 bits (430), Expect = 3e-42
Identities = 88/260 (33%), Positives = 148/260 (56%), Gaps = 7/260 (2%)
Query: 122 LGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQV 181
LGKG+F +V K + ++A K +N +K + + LERE I + +KH +I+ L
Sbjct: 20 LGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 182 FETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKL 241
YLV +L GEL E + + ++SE + I + ++ ++H +DIVHRDLK
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKP 139
Query: 242 ENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYS 301
EN+++ S +K+ DFGLA++ Q +A GTP Y++PEV+ Y
Sbjct: 140 ENLLLASKCK------GAAVKLADFGLAIEVQGEQQAWF-GFAGTPGYLSPEVLRKDPYG 192
Query: 302 QQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQL 361
+ DIW+ GV++Y+LL G PPF + KL++ I+ G F + W++++ AK+++ Q+
Sbjct: 193 KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQM 252
Query: 362 MKVDPAHRITAKELLDNQWL 381
+ ++PA RITA + L + W+
Sbjct: 253 LTINPAKRITADQALKHPWV 272
>gi|26667191 calcium/calmodulin-dependent protein kinase II gamma
isoform 4 [Homo sapiens]
Length = 495
Score = 170 bits (430), Expect = 3e-42
Identities = 88/260 (33%), Positives = 148/260 (56%), Gaps = 7/260 (2%)
Query: 122 LGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQV 181
LGKG+F +V K + ++A K +N +K + + LERE I + +KH +I+ L
Sbjct: 20 LGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 182 FETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKL 241
YLV +L GEL E + + ++SE + I + ++ ++H +DIVHRDLK
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKP 139
Query: 242 ENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYS 301
EN+++ S +K+ DFGLA++ Q +A GTP Y++PEV+ Y
Sbjct: 140 ENLLLASKCK------GAAVKLADFGLAIEVQGEQQAWF-GFAGTPGYLSPEVLRKDPYG 192
Query: 302 QQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQL 361
+ DIW+ GV++Y+LL G PPF + KL++ I+ G F + W++++ AK+++ Q+
Sbjct: 193 KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQM 252
Query: 362 MKVDPAHRITAKELLDNQWL 381
+ ++PA RITA + L + W+
Sbjct: 253 LTINPAKRITADQALKHPWV 272
>gi|26667211 calcium/calmodulin-dependent protein kinase II gamma
isoform 6 [Homo sapiens]
Length = 504
Score = 170 bits (430), Expect = 3e-42
Identities = 88/260 (33%), Positives = 148/260 (56%), Gaps = 7/260 (2%)
Query: 122 LGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQV 181
LGKG+F +V K + ++A K +N +K + + LERE I + +KH +I+ L
Sbjct: 20 LGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 182 FETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKL 241
YLV +L GEL E + + ++SE + I + ++ ++H +DIVHRDLK
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKP 139
Query: 242 ENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYS 301
EN+++ S +K+ DFGLA++ Q +A GTP Y++PEV+ Y
Sbjct: 140 ENLLLASKCK------GAAVKLADFGLAIEVQGEQQAWF-GFAGTPGYLSPEVLRKDPYG 192
Query: 302 QQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQL 361
+ DIW+ GV++Y+LL G PPF + KL++ I+ G F + W++++ AK+++ Q+
Sbjct: 193 KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQM 252
Query: 362 MKVDPAHRITAKELLDNQWL 381
+ ++PA RITA + L + W+
Sbjct: 253 LTINPAKRITADQALKHPWV 272
>gi|26667203 calcium/calmodulin-dependent protein kinase II gamma
isoform 1 [Homo sapiens]
Length = 556
Score = 170 bits (430), Expect = 3e-42
Identities = 88/260 (33%), Positives = 148/260 (56%), Gaps = 7/260 (2%)
Query: 122 LGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQV 181
LGKG+F +V K + ++A K +N +K + + LERE I + +KH +I+ L
Sbjct: 20 LGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 182 FETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKL 241
YLV +L GEL E + + ++SE + I + ++ ++H +DIVHRDLK
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKP 139
Query: 242 ENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYS 301
EN+++ S +K+ DFGLA++ Q +A GTP Y++PEV+ Y
Sbjct: 140 ENLLLASKCK------GAAVKLADFGLAIEVQGEQQAWF-GFAGTPGYLSPEVLRKDPYG 192
Query: 302 QQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQL 361
+ DIW+ GV++Y+LL G PPF + KL++ I+ G F + W++++ AK+++ Q+
Sbjct: 193 KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQM 252
Query: 362 MKVDPAHRITAKELLDNQWL 381
+ ++PA RITA + L + W+
Sbjct: 253 LTINPAKRITADQALKHPWV 272
>gi|26667196 calcium/calmodulin-dependent protein kinase II gamma
isoform 2 [Homo sapiens]
Length = 527
Score = 170 bits (430), Expect = 3e-42
Identities = 88/260 (33%), Positives = 148/260 (56%), Gaps = 7/260 (2%)
Query: 122 LGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQV 181
LGKG+F +V K + ++A K +N +K + + LERE I + +KH +I+ L
Sbjct: 20 LGKGAFSVVRRCVKKTSTQEYAAKIINTKKLSARDHQKLEREARICRLLKHPNIVRLHDS 79
Query: 182 FETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKL 241
YLV +L GEL E + + ++SE + I + ++ ++H +DIVHRDLK
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIHQILESVNHIHQHDIVHRDLKP 139
Query: 242 ENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYS 301
EN+++ S +K+ DFGLA++ Q +A GTP Y++PEV+ Y
Sbjct: 140 ENLLLASKCK------GAAVKLADFGLAIEVQGEQQAWF-GFAGTPGYLSPEVLRKDPYG 192
Query: 302 QQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQL 361
+ DIW+ GV++Y+LL G PPF + KL++ I+ G F + W++++ AK+++ Q+
Sbjct: 193 KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQM 252
Query: 362 MKVDPAHRITAKELLDNQWL 381
+ ++PA RITA + L + W+
Sbjct: 253 LTINPAKRITADQALKHPWV 272
>gi|4557511 death-associated protein kinase 3 [Homo sapiens]
Length = 454
Score = 170 bits (430), Expect = 3e-42
Identities = 95/283 (33%), Positives = 157/283 (55%), Gaps = 11/283 (3%)
Query: 112 IEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSS----AVKLLEREVNIL 167
+E+ Y G LG G F IV + K T ++A K + K + SS + + +EREVNIL
Sbjct: 9 VEDHYEMGEELGSGQFAIVRKCRQKGTGKEYAAKFIKKRRLSSSRRGVSREEIEREVNIL 68
Query: 168 KSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIA 227
+ ++H +II L +FE + L++EL GEL + L K +E+E ++ + +
Sbjct: 69 REIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGVH 128
Query: 228 YLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTP 287
YLH+ I H DLK ENIM+ D N N IK+ DFG+A K ++ +E + GTP
Sbjct: 129 YLHSKRIAHFDLKPENIMLL-----DKNVPNPRIKLIDFGIAHKIEAGNE--FKNIFGTP 181
Query: 288 IYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVW 347
++APE+++ + D+WSIGV+ Y+LL G PFL ++++ I F+ +
Sbjct: 182 EFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGETKQETLTNISAVNYDFDEEYF 241
Query: 348 NSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVR 390
++ S+ AK +++L+ DP R+T + L++ W+ + +VR
Sbjct: 242 SNTSELAKDFIRRLLVKDPKRRMTIAQSLEHSWIKAIRRRNVR 284
>gi|7662170 AMPK-related protein kinase 5 [Homo sapiens]
Length = 661
Score = 170 bits (430), Expect = 3e-42
Identities = 126/447 (28%), Positives = 206/447 (46%), Gaps = 76/447 (17%)
Query: 116 YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKL-LEREVNILKSVKHEH 174
Y LGKG++G V AT++ + AIK + K+K + + RE+ I+ S+ H H
Sbjct: 55 YELQETLGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPH 114
Query: 175 IIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDI 234
II + +VFE K+ ++ME GEL + + + SE ETR + + SA+ Y H N +
Sbjct: 115 IISIYEVFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGV 174
Query: 235 VHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEV 294
VHRDLKLENI L+DD N NIK+ DFGL+ Q + LQ CG+P+Y +PE+
Sbjct: 175 VHRDLKLENI-----LLDD----NCNIKIADFGLSNLYQ--KDKFLQTFCGSPLYASPEI 223
Query: 295 ISAHDY-SQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDC 353
++ Y + D W++GV++Y L+ G PF + L I GE SD
Sbjct: 224 VNGRPYRGPEVDSWALGVLLYTLVYGTMPFDGFDHKNLIRQISSGEYREP----TQPSD- 278
Query: 354 AKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSV------------------------ 389
A+ +++ ++ V+P R T +++ ++ W+ SSV
Sbjct: 279 ARGLIRWMLMVNPDRRATIEDIANHWWVNWGYKSSVCDCDALHDSESPLLARIIDWHHRS 338
Query: 390 ---------------RPTNVLEMMKEWKNNPESVEENTTEEKNK---PSTEEKLKSYQPW 431
+PT M++ ++ +S +EN + + P + KL S +P
Sbjct: 339 TGLQADTEAKMKGLAKPTTSEVMLERQRSLKKSKKENDFAQSGQDAVPESPSKLSSKRPK 398
Query: 432 GNVPDANYTSDEEEEKQSTAYEK-----QFPATSKDNFDMCSSSFTSSKLLPAEIKGEME 486
G + S+ E ST + + P+T K D+C + AE+ G++
Sbjct: 399 GIL---KKRSNSEHRSHSTGFIEGVVGPALPSTFKMEQDLCRTGVLLPSSPEAEVPGKL- 454
Query: 487 KTPVTPSQGTATKYPAKSGALSRTKKK 513
+P Q K G L +T+++
Sbjct: 455 ----SPKQSATM---PKKGILKKTQQR 474
>gi|116089335 BR serine/threonine kinase 2 [Homo sapiens]
Length = 668
Score = 169 bits (428), Expect = 6e-42
Identities = 97/271 (35%), Positives = 154/271 (56%), Gaps = 16/271 (5%)
Query: 116 YTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHI 175
Y + LGKG G+V T K AIK VN+EK S + +ERE+ ILK ++H H+
Sbjct: 19 YRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSESVLMKVEREIAILKLIEHPHV 78
Query: 176 IHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIV 235
+ L V+E K +YLV+E GEL + L +KG + E R + + SA+ + H++ I
Sbjct: 79 LKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSIC 138
Query: 236 HRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVI 295
HRDLK EN+ L+D+ N NI++ DFG+A +++L+ +CG+P Y PEVI
Sbjct: 139 HRDLKPENL-----LLDEKN----NIRIADFGMA--SLQVGDSLLETSCGSPHYACPEVI 187
Query: 296 SAHDY-SQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCA 354
Y ++ D+WS GV+++ LL G PF + +L E +++G H + + DC
Sbjct: 188 RGEKYDGRKADVWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVFHMPHFI---PPDC- 243
Query: 355 KSVLKQLMKVDPAHRITAKELLDNQWLTGNK 385
+S+L+ +++VD A R+T + + + W G K
Sbjct: 244 QSLLRGMIEVDAARRLTLEHIQKHIWYIGGK 274
>gi|24308326 BR serine/threonine kinase 1 [Homo sapiens]
Length = 778
Score = 168 bits (425), Expect = 1e-41
Identities = 98/285 (34%), Positives = 157/285 (55%), Gaps = 16/285 (5%)
Query: 102 PHIRIENGAAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLE 161
PH A Y + LGKG G+V T K AIK VN+EK S + +E
Sbjct: 20 PHPHPPQHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNREKLSESVLMKVE 79
Query: 162 REVNILKSVKHEHIIHLEQVFETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQS 221
RE+ ILK ++H H++ L V+E K +YLV+E GEL + L +KG + E R +
Sbjct: 80 REIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQ 139
Query: 222 LASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQ 281
+ SA+ + H+ I HRDLK EN+ L+D+ N NI++ DFG+A +++L+
Sbjct: 140 IVSALDFCHSYSICHRDLKPENL-----LLDEKN----NIRIADFGMA--SLQVGDSLLE 188
Query: 282 ATCGTPIYMAPEVISAHDY-SQQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGEL 340
+CG+P Y PEVI Y ++ D+WS GV+++ LL G PF + +L E +++G
Sbjct: 189 TSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDNLRQLLEKVKRGVF 248
Query: 341 HFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNK 385
H + + DC +S+L+ +++V+P R++ +++ + W G K
Sbjct: 249 HMPHFI---PPDC-QSLLRGMIEVEPEKRLSLEQIQKHPWYLGGK 289
>gi|32481209 mitogen-activated protein kinase-activated protein
kinase 2 isoform 2 [Homo sapiens]
Length = 400
Score = 166 bits (420), Expect = 5e-41
Identities = 102/320 (31%), Positives = 169/320 (52%), Gaps = 24/320 (7%)
Query: 104 IRIENGAAIEEIYTFGRILGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLERE 163
++I+ A I++ ++LG G G V++ +K T+ K+A+K + V+L R
Sbjct: 52 LQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWR- 110
Query: 164 VNILKSVKHEHIIHLEQVFET----PKKMYLVMELCEDGELKEILDRKGH--FSENETRW 217
+ + HI+ + V+E K + +VME + GEL + +G F+E E
Sbjct: 111 -----ASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASE 165
Query: 218 IIQSLASAIAYLHNNDIVHRDLKLENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSE 277
I++S+ AI YLH+ +I HRD+K EN++ S N +K+TDFG A K++ S
Sbjct: 166 IMKSIGEAIQYLHSINIAHRDVKPENLLYTSK------RPNAILKLTDFGFA--KETTSH 217
Query: 278 AMLQATCGTPIYMAPEVISAHDYSQQCDIWSIGVVMYMLLRGEPPFLASS----EEKLFE 333
L C TP Y+APEV+ Y + CD+WS+GV+MY+LL G PPF ++ +
Sbjct: 218 NSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKT 277
Query: 334 LIRKGELHFENAVWNSISDCAKSVLKQLMKVDPAHRITAKELLDNQWLTGNKLSSVRPTN 393
IR G+ F N W+ +S+ K +++ L+K +P R+T E +++ W+ + P +
Sbjct: 278 RIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLH 337
Query: 394 VLEMMKEWKNNPESVEENTT 413
++KE K E V+E T
Sbjct: 338 TSRVLKEDKERWEDVKEEMT 357
>gi|26051218 calcium/calmodulin-dependent protein kinase II beta
isoform 8 [Homo sapiens]
Length = 449
Score = 166 bits (420), Expect = 5e-41
Identities = 106/356 (29%), Positives = 180/356 (50%), Gaps = 29/356 (8%)
Query: 122 LGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQV 181
+GKG+F +V T ++A K +N +K + + LERE I + +KH +I+ L
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 182 FETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKL 241
YLV +L GEL E + + ++SE + IQ + A+ + H +VHRDLK
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKP 139
Query: 242 ENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYS 301
EN+++ S +K+ DFGLA++ Q +A GTP Y++PEV+ Y
Sbjct: 140 ENLLLASKCK------GAAVKLADFGLAIEVQGDQQAWF-GFAGTPGYLSPEVLRKEAYG 192
Query: 302 QQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQL 361
+ DIW+ GV++Y+LL G PPF + KL++ I+ G F + W++++ AK+++ Q+
Sbjct: 193 KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQM 252
Query: 362 MKVDPAHRITAKELLDNQWLTGNKLSSVRPTNVLEMMKEWKNNPESVEENTTEEKNKPST 421
+ ++PA RITA E L + W+ + + V MM + T E K +
Sbjct: 253 LTINPAKRITAHEALKHPWV-------CQRSTVASMMH---------RQETVECLKKFNA 296
Query: 422 EEKLKSYQPWGNVPDANYTSDEEEEKQSTAYEKQFPATSKDNFD----MCSSSFTS 473
KLK + N+++ ++E ++T E+ A + +F+ +C TS
Sbjct: 297 RRKLKGAILTTMLATRNFSARKQEIIKTT--EQLIEAVNNGDFEAYAKICDPGLTS 350
>gi|26051204 calcium/calmodulin-dependent protein kinase II beta
isoform 1 [Homo sapiens]
Length = 666
Score = 165 bits (417), Expect = 1e-40
Identities = 88/260 (33%), Positives = 145/260 (55%), Gaps = 7/260 (2%)
Query: 122 LGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQV 181
+GKG+F +V T ++A K +N +K + + LERE I + +KH +I+ L
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 182 FETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKL 241
YLV +L GEL E + + ++SE + IQ + A+ + H +VHRDLK
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKP 139
Query: 242 ENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYS 301
EN+++ S +K+ DFGLA++ Q +A GTP Y++PEV+ Y
Sbjct: 140 ENLLLASKCK------GAAVKLADFGLAIEVQGDQQAWF-GFAGTPGYLSPEVLRKEAYG 192
Query: 302 QQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQL 361
+ DIW+ GV++Y+LL G PPF + KL++ I+ G F + W++++ AK+++ Q+
Sbjct: 193 KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQM 252
Query: 362 MKVDPAHRITAKELLDNQWL 381
+ ++PA RITA E L + W+
Sbjct: 253 LTINPAKRITAHEALKHPWV 272
>gi|26051210 calcium/calmodulin-dependent protein kinase II beta
isoform 4 [Homo sapiens]
Length = 517
Score = 165 bits (417), Expect = 1e-40
Identities = 88/260 (33%), Positives = 145/260 (55%), Gaps = 7/260 (2%)
Query: 122 LGKGSFGIVIEATDKETETKWAIKKVNKEKAGSSAVKLLEREVNILKSVKHEHIIHLEQV 181
+GKG+F +V T ++A K +N +K + + LERE I + +KH +I+ L
Sbjct: 20 IGKGAFSVVRRCVKLCTGHEYAAKIINTKKLSARDHQKLEREARICRLLKHSNIVRLHDS 79
Query: 182 FETPKKMYLVMELCEDGELKEILDRKGHFSENETRWIIQSLASAIAYLHNNDIVHRDLKL 241
YLV +L GEL E + + ++SE + IQ + A+ + H +VHRDLK
Sbjct: 80 ISEEGFHYLVFDLVTGGELFEDIVAREYYSEADASHCIQQILEAVLHCHQMGVVHRDLKP 139
Query: 242 ENIMVKSSLIDDNNEINLNIKVTDFGLAVKKQSRSEAMLQATCGTPIYMAPEVISAHDYS 301
EN+++ S +K+ DFGLA++ Q +A GTP Y++PEV+ Y
Sbjct: 140 ENLLLASKCK------GAAVKLADFGLAIEVQGDQQAWF-GFAGTPGYLSPEVLRKEAYG 192
Query: 302 QQCDIWSIGVVMYMLLRGEPPFLASSEEKLFELIRKGELHFENAVWNSISDCAKSVLKQL 361
+ DIW+ GV++Y+LL G PPF + KL++ I+ G F + W++++ AK+++ Q+
Sbjct: 193 KPVDIWACGVILYILLVGYPPFWDEDQHKLYQQIKAGAYDFPSPEWDTVTPEAKNLINQM 252
Query: 362 MKVDPAHRITAKELLDNQWL 381
+ ++PA RITA E L + W+
Sbjct: 253 LTINPAKRITAHEALKHPWV 272
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.359
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,938,248
Number of Sequences: 37866
Number of extensions: 838313
Number of successful extensions: 5331
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 670
Number of HSP's successfully gapped in prelim test: 197
Number of HSP's that attempted gapping in prelim test: 2831
Number of HSP's gapped (non-prelim): 1112
length of query: 514
length of database: 18,247,518
effective HSP length: 107
effective length of query: 407
effective length of database: 14,195,856
effective search space: 5777713392
effective search space used: 5777713392
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.