Guide to the Human Genome
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Search of human proteins with 237681111

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo
sapiens]
         (992 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi...  1978   0.0  
gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi...  1978   0.0  
gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]  1978   0.0  
gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]            1774   0.0  
gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]  1768   0.0  
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi...  1599   0.0  
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]  1326   0.0  
gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]   1317   0.0  
gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap...   372   e-102
gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap...   372   e-102
gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap...   372   e-102
gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap...   372   e-102
gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom...   369   e-101
gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom...   369   e-101
gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom...   369   e-101
gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom...   369   e-101
gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom...   369   e-101
gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom...   369   e-101
gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom...   369   e-101
gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H...   357   3e-98
gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [...   357   3e-98
gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [...   355   1e-97
gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [...   355   1e-97
gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ...   353   6e-97
gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 ...   330   5e-90
gi|49249977 Na+/K+ -ATPase alpha 4 subunit isoform 2 [Homo sapiens]   288   1e-77
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap...   273   8e-73
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa...   237   4e-62
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa...   237   4e-62
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa...   236   8e-62

>gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapiens]
          Length = 1023

 Score = 1978 bits (5124), Expect = 0.0
 Identities = 992/992 (100%), Positives = 992/992 (100%)

Query: 1    MDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIK 60
            MDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIK
Sbjct: 32   MDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIK 91

Query: 61   FCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQE 120
            FCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQE
Sbjct: 92   FCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQE 151

Query: 121  AKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGC 180
            AKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGC
Sbjct: 152  AKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGC 211

Query: 181  KVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIA 240
            KVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIA
Sbjct: 212  KVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIA 271

Query: 241  TLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVAN 300
            TLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVAN
Sbjct: 272  TLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVAN 331

Query: 301  VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM 360
            VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM
Sbjct: 332  VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM 391

Query: 361  WFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDA 420
            WFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDA
Sbjct: 392  WFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDA 451

Query: 421  SESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAP 480
            SESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAP
Sbjct: 452  SESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAP 511

Query: 481  ERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQF 540
            ERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQF
Sbjct: 512  ERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQF 571

Query: 541  DTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV 600
            DTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV
Sbjct: 572  DTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV 631

Query: 601  GIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFA 660
            GIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFA
Sbjct: 632  GIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFA 691

Query: 661  RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 720
            RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL
Sbjct: 692  RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 751

Query: 721  DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCID 780
            DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCID
Sbjct: 752  DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCID 811

Query: 781  LGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFV 840
            LGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFV
Sbjct: 812  LGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFV 871

Query: 841  ILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQW 900
            ILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQW
Sbjct: 872  ILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQW 931

Query: 901  ADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCA 960
            ADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCA
Sbjct: 932  ADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCA 991

Query: 961  FPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 992
            FPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY
Sbjct: 992  FPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 1023


>gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo
           sapiens]
          Length = 992

 Score = 1978 bits (5124), Expect = 0.0
 Identities = 992/992 (100%), Positives = 992/992 (100%)

Query: 1   MDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIK 60
           MDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIK
Sbjct: 1   MDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIK 60

Query: 61  FCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQE 120
           FCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQE
Sbjct: 61  FCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQE 120

Query: 121 AKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGC 180
           AKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGC
Sbjct: 121 AKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGC 180

Query: 181 KVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIA 240
           KVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIA
Sbjct: 181 KVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIA 240

Query: 241 TLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVAN 300
           TLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVAN
Sbjct: 241 TLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVAN 300

Query: 301 VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM 360
           VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM
Sbjct: 301 VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM 360

Query: 361 WFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDA 420
           WFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDA
Sbjct: 361 WFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDA 420

Query: 421 SESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAP 480
           SESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAP
Sbjct: 421 SESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAP 480

Query: 481 ERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQF 540
           ERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQF
Sbjct: 481 ERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQF 540

Query: 541 DTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV 600
           DTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV
Sbjct: 541 DTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV 600

Query: 601 GIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFA 660
           GIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFA
Sbjct: 601 GIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFA 660

Query: 661 RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 720
           RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL
Sbjct: 661 RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 720

Query: 721 DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCID 780
           DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCID
Sbjct: 721 DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCID 780

Query: 781 LGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFV 840
           LGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFV
Sbjct: 781 LGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFV 840

Query: 841 ILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQW 900
           ILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQW
Sbjct: 841 ILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQW 900

Query: 901 ADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCA 960
           ADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCA
Sbjct: 901 ADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCA 960

Query: 961 FPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 992
           FPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY
Sbjct: 961 FPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 992


>gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]
          Length = 1023

 Score = 1978 bits (5124), Expect = 0.0
 Identities = 992/992 (100%), Positives = 992/992 (100%)

Query: 1    MDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIK 60
            MDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIK
Sbjct: 32   MDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIK 91

Query: 61   FCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQE 120
            FCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQE
Sbjct: 92   FCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQE 151

Query: 121  AKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGC 180
            AKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGC
Sbjct: 152  AKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGC 211

Query: 181  KVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIA 240
            KVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIA
Sbjct: 212  KVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIA 271

Query: 241  TLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVAN 300
            TLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVAN
Sbjct: 272  TLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVAN 331

Query: 301  VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM 360
            VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM
Sbjct: 332  VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM 391

Query: 361  WFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDA 420
            WFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDA
Sbjct: 392  WFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDA 451

Query: 421  SESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAP 480
            SESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAP
Sbjct: 452  SESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAP 511

Query: 481  ERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQF 540
            ERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQF
Sbjct: 512  ERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQF 571

Query: 541  DTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV 600
            DTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV
Sbjct: 572  DTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV 631

Query: 601  GIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFA 660
            GIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFA
Sbjct: 632  GIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFA 691

Query: 661  RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 720
            RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL
Sbjct: 692  RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 751

Query: 721  DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCID 780
            DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCID
Sbjct: 752  DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCID 811

Query: 781  LGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFV 840
            LGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFV
Sbjct: 812  LGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFV 871

Query: 841  ILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQW 900
            ILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQW
Sbjct: 872  ILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQW 931

Query: 901  ADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCA 960
            ADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCA
Sbjct: 932  ADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCA 991

Query: 961  FPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 992
            FPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY
Sbjct: 992  FPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 1023


>gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens]
          Length = 1013

 Score = 1774 bits (4595), Expect = 0.0
 Identities = 873/992 (88%), Positives = 942/992 (94%)

Query: 1    MDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIK 60
            +D+LKKEV+M +HK+S++E+ RKY TD  +GLT ++A EILARDGPNALTPPPTTPEW+K
Sbjct: 22   LDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVK 81

Query: 61   FCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQE 120
            FCRQLFGGFS+LLWIGAILCFLAY IQA TE++P  DNLYLG+VL+AVVIITGCFSYYQE
Sbjct: 82   FCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQE 141

Query: 121  AKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGC 180
            AKSSKIMESFKNMVPQQALVIR GEKM +NAEEVVVGDLVE+KGGDR+PADLRIISA+GC
Sbjct: 142  AKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGC 201

Query: 181  KVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIA 240
            KVDNSSLTGESEPQTRSPD T++NPLETRNI FFSTNCVEGTARG+VV TGDRTVMGRIA
Sbjct: 202  KVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVVATGDRTVMGRIA 261

Query: 241  TLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVAN 300
            TLASGLE G+TPIA EIEHFI +ITGVAVFLGVSFFILSLIL YTWLEAVIFLIGIIVAN
Sbjct: 262  TLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAVIFLIGIIVAN 321

Query: 301  VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM 360
            VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM
Sbjct: 322  VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM 381

Query: 361  WFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDA 420
            WFDNQIHEADTTE+QSG SFDK+S TW+ALS IAGLCNRAVF+  Q+N+P+LKR VAGDA
Sbjct: 382  WFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNRAVFKGGQDNIPVLKRDVAGDA 441

Query: 421  SESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAP 480
            SESALLKCIEL  GSVK MRER  K+ EIPFNSTNKYQLSIH+  + ++ ++LLVMKGAP
Sbjct: 442  SESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQLSIHETEDPNDNRYLLVMKGAP 501

Query: 481  ERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQF 540
            ERILDRCS+ILL GKEQPLDEE+K+AFQNAYLELGGLGERVLGFCH +LP+EQFP+GF F
Sbjct: 502  ERILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAF 561

Query: 541  DTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV 600
            D DDVNF  DNLCFVGL+SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV
Sbjct: 562  DCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV 621

Query: 601  GIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFA 660
            GIISEGNETVEDIAARLNIPVSQVNPRDAKACV+HG+DLKD TSEQ+D+IL+ HTEIVFA
Sbjct: 622  GIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFA 681

Query: 661  RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 720
            RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL
Sbjct: 682  RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 741

Query: 721  DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCID 780
            DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFL+FI+ANIPLPLGT+TILCID
Sbjct: 742  DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCID 801

Query: 781  LGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFV 840
            LGTDMVPAISLAYE AESDIMKRQPRNP+TDKLVNERLISMAYGQIGMIQALGGFF+YFV
Sbjct: 802  LGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQALGGFFSYFV 861

Query: 841  ILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQW 900
            ILAENGFLP +L+G+R++WDDR +ND+EDSYGQQWTYEQRK+VEFTCHTAFFVSIVVVQW
Sbjct: 862  ILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQRKVVEFTCHTAFFVSIVVVQW 921

Query: 901  ADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCA 960
            ADL+ICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGM VALRMYPLKP+WWFCA
Sbjct: 922  ADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDVALRMYPLKPSWWFCA 981

Query: 961  FPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 992
            FPYS LIFVYDE+RKLI+RR PGGWVEKETYY
Sbjct: 982  FPYSFLIFVYDEIRKLILRRNPGGWVEKETYY 1013


>gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens]
          Length = 1020

 Score = 1768 bits (4579), Expect = 0.0
 Identities = 875/992 (88%), Positives = 939/992 (94%), Gaps = 1/992 (0%)

Query: 1    MDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIK 60
            +DELKKEV+MDDHKLSLDEL RKY  DLS+GLT+ RA ++LARDGPNALTPPPTTPEW+K
Sbjct: 30   LDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTPPPTTPEWVK 89

Query: 61   FCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQE 120
            FCRQLFGGFS+LLWIGAILCFLAY IQAA E+EP NDNLYLGVVL+AVVI+TGCFSYYQE
Sbjct: 90   FCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQE 149

Query: 121  AKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGC 180
            AKSSKIM+SFKNMVPQQALVIR GEKM INAEEVVVGDLVEVKGGDR+PADLRIIS++GC
Sbjct: 150  AKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGC 209

Query: 181  KVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIA 240
            KVDNSSLTGESEPQTRSP+FT+ENPLETRNI FFSTNCVEGTARGIV+ TGDRTVMGRIA
Sbjct: 210  KVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIA 269

Query: 241  TLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVAN 300
            TLASGLE G+TPIA EIEHFI +ITGVAVFLGVSFF+LSLIL Y+WLEAVIFLIGIIVAN
Sbjct: 270  TLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVAN 329

Query: 301  VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM 360
            VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM
Sbjct: 330  VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM 389

Query: 361  WFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDA 420
            WFDNQIHEADTTE+QSG +FDK S TW ALSRIAGLCNRAVF+A QEN+ + KR  AGDA
Sbjct: 390  WFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDA 449

Query: 421  SESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAP 480
            SESALLKCIEL CGSV++MR+R  K+ EIPFNSTNKYQLSIH+  ++ +  H+LVMKGAP
Sbjct: 450  SESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQ-SHVLVMKGAP 508

Query: 481  ERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQF 540
            ERILDRCS+IL+ GKE PLD+E++DAFQNAY+ELGGLGERVLGFC L LP  +FP GF+F
Sbjct: 509  ERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKF 568

Query: 541  DTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV 600
            DTD++NFP + LCFVGL+SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV
Sbjct: 569  DTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV 628

Query: 601  GIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFA 660
            GIISEGNETVEDIAARLNIP+SQVNPR+AKACVVHGSDLKDMTSEQLD+ILK HTEIVFA
Sbjct: 629  GIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFA 688

Query: 661  RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 720
            RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIG+AMGI+GSDVSKQAADMILL
Sbjct: 689  RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILL 748

Query: 721  DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCID 780
            DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFL+FIIANIPLPLGTVTILCID
Sbjct: 749  DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCID 808

Query: 781  LGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFV 840
            LGTDMVPAISLAYE AESDIMKRQPRN +TDKLVNERLISMAYGQIGMIQALGGFFTYFV
Sbjct: 809  LGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQALGGFFTYFV 868

Query: 841  ILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQW 900
            ILAENGFLP  LLG+R+DWDDR +ND+EDSYGQ+WTYEQRK+VEFTCHTAFF SIVVVQW
Sbjct: 869  ILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQW 928

Query: 901  ADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCA 960
            ADL+ICKTRRNSVFQQGMKNKILIFGL EETALAAFLSYCPGMGVALRMYPLK TWWFCA
Sbjct: 929  ADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCA 988

Query: 961  FPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 992
            FPYSLLIF+YDEVRKLI+RR PGGWVEKETYY
Sbjct: 989  FPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 1020


>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapiens]
          Length = 1029

 Score = 1599 bits (4141), Expect = 0.0
 Identities = 793/992 (79%), Positives = 883/992 (89%), Gaps = 2/992 (0%)

Query: 1    MDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIK 60
            M+ELKKEV MDDHKL+L+EL  KY  DL++G +  RA EIL R GPN +TPPPTTPEW+K
Sbjct: 40   MEELKKEVVMDDHKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTTPEWVK 99

Query: 61   FCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQE 120
            FC+QLFGGFS+LLW GAILCF+AYSIQ    EEP  DNLYL +VLS VVI+TGCFSYYQE
Sbjct: 100  FCKQLFGGFSLLLWTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVVIVTGCFSYYQE 159

Query: 121  AKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGC 180
            AKSSKIMESFKNMVPQQALVIR GEKM IN +EVV+GDLVE+KGGDR+PADLR+ISA GC
Sbjct: 160  AKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLISAQGC 219

Query: 181  KVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIA 240
            KVDNSSLTGESEPQ+RSPDFT+ENPLETRNI FFSTNCVEGTARGIV+ TGD TVMGRIA
Sbjct: 220  KVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTVMGRIA 279

Query: 241  TLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVAN 300
            +L SGL  GQTPIAAEIEHFIH+IT VAVFLGV+FF LSL+L Y WLEA+IFLIGIIVAN
Sbjct: 280  SLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEAIIFLIGIIVAN 339

Query: 301  VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM 360
            VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM
Sbjct: 340  VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM 399

Query: 361  WFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDA 420
            WFD  ++EADTTE Q+G +F K+S TW  L+RIAGLCNRA F+ANQE LPI KRA  GDA
Sbjct: 400  WFDMTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKANQEILPIAKRATTGDA 459

Query: 421  SESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAP 480
            SESALLK IE    SV EMRE+  K+ EIPFNSTNKYQ+SIH   ++S+  H+L+MKGAP
Sbjct: 460  SESALLKFIEQSYSSVAEMREKNPKVAEIPFNSTNKYQMSIHLREDSSQT-HVLMMKGAP 518

Query: 481  ERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQF 540
            ERIL+ CS+ LL+G+E  +++E+K+AFQNAYLELGGLGERVLGFC L LP   F +GF F
Sbjct: 519  ERILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLGFCFLNLPSS-FSKGFPF 577

Query: 541  DTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV 600
            +TD++NFP+DNLCFVGLISMIDPPRAAVPDAV KCRSAGIKVIMVTGDHPITAKAIAKGV
Sbjct: 578  NTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKAIAKGV 637

Query: 601  GIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFA 660
            GIISEG ET E++AARL IP+S+V+   AKA VVHG++LKD+ S+QLD IL+ H EIVFA
Sbjct: 638  GIISEGTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHPEIVFA 697

Query: 661  RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 720
            RTSPQQKLIIVEGCQR GA+VAVTGDGVNDSPALKKADIG+AMGI+GSDVSKQAADMILL
Sbjct: 698  RTSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILL 757

Query: 721  DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCID 780
            DDNFASIVTGVEEGRLIFDNLKKSI YTLTSNIPEITPFL+FII  IPLPLGT+TILCID
Sbjct: 758  DDNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTITILCID 817

Query: 781  LGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFV 840
            LGTDMVPAISLAYE AESDIMKR PRNPKTD LVN RLI MAYGQIGMIQAL GFFTYFV
Sbjct: 818  LGTDMVPAISLAYESAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMIQALAGFFTYFV 877

Query: 841  ILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQW 900
            ILAENGF P+ LLG+R+ W+D+++ND+EDSYGQQWTYEQRK+VEFTC TAFFV+IVVVQW
Sbjct: 878  ILAENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTCQTAFFVTIVVVQW 937

Query: 901  ADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCA 960
            ADL+I KTRRNS+FQQGM+NK+LIFG+ EET LAAFLSY PGM VALRMYPLK TWW CA
Sbjct: 938  ADLIISKTRRNSLFQQGMRNKVLIFGILEETLLAAFLSYTPGMDVALRMYPLKITWWLCA 997

Query: 961  FPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 992
             PYS+LIFVYDE+RKL+IR+ P GWVE+ETYY
Sbjct: 998  IPYSILIFVYDEIRKLLIRQHPDGWVERETYY 1029


>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
          Length = 1039

 Score = 1326 bits (3432), Expect = 0.0
 Identities = 653/992 (65%), Positives = 811/992 (81%), Gaps = 1/992 (0%)

Query: 2    DELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKF 61
            +E +KE+ +DDHKLS  EL  KYGTD+  GL+S RAAE+LARDGPN+LTPP  TPE +KF
Sbjct: 48   EEFQKELHLDDHKLSNRELEEKYGTDIIMGLSSTRAAELLARDGPNSLTPPKQTPEIVKF 107

Query: 62   CRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEA 121
             +Q+ GGFS+LLW+GA LC++AY IQ ++++    +N+YLG VL  VVI+TG F+YYQEA
Sbjct: 108  LKQMVGGFSILLWVGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEA 167

Query: 122  KSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCK 181
            KS+ IM SF  M+PQQALVIR+ EK +I +E++VVGD+VEVKGGD+IPAD+R++S+ GC+
Sbjct: 168  KSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVLSSQGCR 227

Query: 182  VDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIAT 241
            VDNSSLTGESEPQ RS +FT+ENPLET+NI F+ST C+EGT  G+V+ TGDRT++G IA+
Sbjct: 228  VDNSSLTGESEPQPRSSEFTHENPLETKNICFYSTTCLEGTVTGMVINTGDRTIIGHIAS 287

Query: 242  LASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVANV 301
            LASG+   +TPIA EIEHF+HI+ GVAV +G+ FFI+++ L+Y  L+++IFLIGIIVANV
Sbjct: 288  LASGVGNEKTPIAIEIEHFVHIVAGVAVSIGILFFIIAVSLKYQVLDSIIFLIGIIVANV 347

Query: 302  PEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMW 361
            PEGLLATVTV L+LTAKRMA+KNCLVKNLEAVETLGSTS ICSDKTGTLTQNRMTVAH+W
Sbjct: 348  PEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLW 407

Query: 362  FDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDAS 421
            FDNQI  ADT+E+ S   FD++S TW +LS+I  LCNRA F+  QEN+PI+K+AV GDAS
Sbjct: 408  FDNQIFVADTSEDHSNQVFDQSSRTWASLSKIITLCNRAEFKPGQENVPIMKKAVIGDAS 467

Query: 422  ESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAPE 481
            E+ALLK  E+  G V E+R+R  K+ EIPFNSTNK+QLSIH+  +    + L+VMKGAPE
Sbjct: 468  ETALLKFSEVILGDVMEIRKRNRKVAEIPFNSTNKFQLSIHEMDDPHGKRFLMVMKGAPE 527

Query: 482  RILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFD 541
            RIL++CS+I+++G+E PLD+     F  AY+ELGGLGERVLGFCHL+LP ++FPE + FD
Sbjct: 528  RILEKCSTIMINGEEHPLDKSTAKTFHTAYMELGGLGERVLGFCHLYLPADEFPETYSFD 587

Query: 542  TDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVG 601
             D +NFP  NLCFVGL+SMIDPPR+ VPDAV KCRSAGIKVIMVTGDHPITAKAIAK VG
Sbjct: 588  IDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPITAKAIAKSVG 647

Query: 602  IISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFAR 661
            IIS  +ETVEDIA RLNI V QVN RDAKA VV G +LKDM+SEQLD+IL  + EIVFAR
Sbjct: 648  IISANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMSSEQLDEILANYQEIVFAR 707

Query: 662  TSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLD 721
            TSPQQKLIIVEGCQRQ A+VAVTGDGVNDSPALKKADIG+AMGIAGSD +K AADM+LLD
Sbjct: 708  TSPQQKLIIVEGCQRQDAVVAVTGDGVNDSPALKKADIGIAMGIAGSDAAKNAADMVLLD 767

Query: 722  DNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDL 781
            DNFASIVTGVEEGRLIFDNLKK+IAY+LT NI E+ PFLI+II  +PLP+GT+TIL IDL
Sbjct: 768  DNFASIVTGVEEGRLIFDNLKKTIAYSLTKNIAELCPFLIYIIVGLPLPIGTITILFIDL 827

Query: 782  GTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFVI 841
            GTD++P+I+LAYE+AESDIM R+PR+   D+LVN+ L   +Y  IG++QALG F  YF +
Sbjct: 828  GTDIIPSIALAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAFLVYFTV 887

Query: 842  LAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWA 901
             A+ GFLP  L+ LRV+W+  ++ND++DSYGQ+WT  QR+ +E+T +TAFFV I+V Q A
Sbjct: 888  YAQEGFLPRTLINLRVEWEKDYVNDLKDSYGQEWTRYQREYLEWTGYTAFFVGILVQQIA 947

Query: 902  DLVICKTRRNSVFQQGM-KNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCA 960
            DL+I KTRRNS+FQQG+ +NK++  G+  +  +   LSY  G   AL    L+  +WF A
Sbjct: 948  DLIIRKTRRNSIFQQGLFRNKVIWVGITSQIIIGLILSYGLGSVTALSFTMLRAQYWFVA 1007

Query: 961  FPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 992
             P+++LI+VYDEVRKL IR  PG W +K  YY
Sbjct: 1008 VPHAILIWVYDEVRKLFIRLYPGSWWDKNMYY 1039


>gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens]
          Length = 1035

 Score = 1317 bits (3408), Expect = 0.0
 Identities = 635/993 (63%), Positives = 800/993 (80%), Gaps = 1/993 (0%)

Query: 1    MDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIK 60
            ++ +KKE+ ++DH+LS+ EL +KY T  ++GL+++ AAE+L RDGPNAL PP  TPE++K
Sbjct: 43   LENMKKEMEINDHQLSVAELEQKYQTSATKGLSASLAAELLLRDGPNALRPPRGTPEYVK 102

Query: 61   FCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQE 120
            F RQL GG   L+W+ A +C +A++IQA+  +   +DNLYL + L AVV++TGCF YYQE
Sbjct: 103  FARQLAGGLQCLMWVAAAICLIAFAIQASEGDLTTDDNLYLAIALIAVVVVTGCFGYYQE 162

Query: 121  AKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGC 180
             KS+ I+ SFKN+VPQQA VIR+G+K  INA+++VVGDLVE+KGGDR+PAD+RI++A GC
Sbjct: 163  FKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDLVEMKGGDRVPADIRILAAQGC 222

Query: 181  KVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIA 240
            KVDNSSLTGESEPQTRSP+ T+E+PLETRNIAFFST C+EGT +G+VV TGDRT++GRIA
Sbjct: 223  KVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCLEGTVQGLVVNTGDRTIIGRIA 282

Query: 241  TLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVAN 300
            +LASG+E  +TPIA EIEHF+ II G+A+  G +FFI+++ + YT+L A++F + I+VA 
Sbjct: 283  SLASGVENEKTPIAIEIEHFVDIIAGLAILFGATFFIVAMCIGYTFLRAMVFFMAIVVAY 342

Query: 301  VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM 360
            VPEGLLATVTVCL+LTAKR+A KNC+VKNLEAVETLGSTS ICSDKTGTLTQNRMTV+H+
Sbjct: 343  VPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGSTSVICSDKTGTLTQNRMTVSHL 402

Query: 361  WFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDA 420
            WFDN IH ADTTE+QSG +FD++S TW AL R+  LCNRA F++ Q+ +P+ KR V GDA
Sbjct: 403  WFDNHIHTADTTEDQSGQTFDQSSETWRALCRVLTLCNRAAFKSGQDAVPVPKRIVIGDA 462

Query: 421  SESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAP 480
            SE+ALLK  EL  G+    R+R+ K+ EIPFNSTNK+QLSIH   +  +P+HLLVMKGAP
Sbjct: 463  SETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQLSIHTLEDPRDPRHLLVMKGAP 522

Query: 481  ERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQF 540
            ER+L+RCSSIL+ G+E PLDE+ ++AFQ AYL LGGLGERVLGFC L+L ++ +P G+ F
Sbjct: 523  ERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGERVLGFCQLYLNEKDYPPGYAF 582

Query: 541  DTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV 600
            D + +NFP   LCF GL+SMIDPPRA VPDAV KCR+AGI+VIMVTGDHPITAKAIA  V
Sbjct: 583  DVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCRTAGIRVIMVTGDHPITAKAIAASV 642

Query: 601  GIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFA 660
            GIISEG+ETVEDIAARL +PV QVN +DA+ACV++G  LKDM   +L + L+ H E+VFA
Sbjct: 643  GIISEGSETVEDIAARLRVPVDQVNRKDARACVINGMQLKDMDPSELVEALRTHPEMVFA 702

Query: 661  RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 720
            RTSPQQKL+IVE CQR GAIVAVTGDGVNDSPALKKADIGVAMGIAGSD +K AADMILL
Sbjct: 703  RTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDAAKNAADMILL 762

Query: 721  DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCID 780
            DDNFASIVTGVE+GRLIFDNLKKSIAYTLT NIPE+TP+LI+I  ++PLPLG +TIL I+
Sbjct: 763  DDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPYLIYITVSVPLPLGCITILFIE 822

Query: 781  LGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFV 840
            L TD+ P++SLAYE+AESDIM  +PRNPK D+LVNE L + +Y QIG IQ+  GF  YF 
Sbjct: 823  LCTDIFPSVSLAYEKAESDIMHLRPRNPKRDRLVNEPLAAYSYFQIGAIQSFAGFTDYFT 882

Query: 841  ILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQW 900
             +A+ G+ P+  +GLR  W+D  + D++DSYGQ+WT+ QR   ++TC+T FF+SI V Q 
Sbjct: 883  AMAQEGWFPLLCVGLRAQWEDHHLQDLQDSYGQEWTFGQRLYQQYTCYTVFFISIEVCQI 942

Query: 901  ADLVICKTRRNSVFQQG-MKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFC 959
            AD++I KTRR S FQQG  +NKIL+  +  +  +  FL YCPGM       P++  WW  
Sbjct: 943  ADVLIRKTRRLSAFQQGFFRNKILVIAIVFQVCIGCFLCYCPGMPNIFNFMPIRFQWWLV 1002

Query: 960  AFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 992
              PY +LIFVYDE+RKL +R  PG W ++E YY
Sbjct: 1003 PLPYGILIFVYDEIRKLGVRCCPGSWWDQELYY 1035


>gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo
           sapiens]
          Length = 939

 Score =  372 bits (954), Expect = e-102
 Identities = 269/855 (31%), Positives = 419/855 (49%), Gaps = 96/855 (11%)

Query: 14  KLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSMLL 73
           +L + E+      DL  GL     +   A  G N        P W K+  Q      MLL
Sbjct: 28  ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87

Query: 74  WIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNM 133
              A++  L +    A             V ++  ++I    ++ QE +S K +E    +
Sbjct: 88  LASAVISVLMHQFDDA-------------VSITVAILIVVTVAFVQEYRSEKSLEELSKL 134

Query: 134 VPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEP 193
           VP +   +R G+     A ++V GD V +  GDR+PADLR+  A    +D SSLTGE+ P
Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194

Query: 194 QTR----SPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGG 249
            ++     P  TN +     NIAF  T    G A+G+V+ TG+ +  G +  +    E  
Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254

Query: 250 QTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWL------EAVIFLIGIIVANVPE 303
           +TP+   ++     + G  +    SF I+ +I+   WL      E     + + VA +PE
Sbjct: 255 KTPLQKSMD-----LLGKQLSF-YSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPE 308

Query: 304 GLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFD 363
           GL   VTV L L   RM +K  +VK L  VETLG  + ICSDKTGTLT+N MTV H++  
Sbjct: 309 GLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTS 368

Query: 364 NQIHEADTTE--NQSG---VSFDKTSATWL-ALSRI--AG-LCNRAVFQANQENLPILKR 414
           + +H   T    NQ G   V  D     +  A+SRI  AG +CN AV + N         
Sbjct: 369 DGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNN--------- 419

Query: 415 AVAGDASESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLL 474
            + G  +E AL+  + +  G +  +++ Y +  E PF+S  K+      +    +   + 
Sbjct: 420 TLMGKPTEGALI-ALAMKMG-LDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEIC 477

Query: 475 VMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQF 534
            MKGA E+++  C++    G+   L ++ +D +Q     +G  G RVL            
Sbjct: 478 FMKGAYEQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALA-------SG 530

Query: 535 PEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAK 594
           PE            +  L F+GL+ +IDPPR  V +AV    ++G+ + M+TGD   TA 
Sbjct: 531 PE------------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAV 578

Query: 595 AIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYH 654
           AIA  +G+ S+ +++V                         G ++  M  +QL  I+   
Sbjct: 579 AIASRLGLYSKTSQSVS------------------------GEEIDAMDVQQLSQIVP-- 612

Query: 655 TEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQA 714
              VF R SP+ K+ I++  Q+ G++VA+TGDGVND+ ALK ADIGVAMG  G+DV K+A
Sbjct: 613 KVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEA 672

Query: 715 ADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTV 774
           ADMIL+DD+F +I++ +EEG+ I++N+K  + + L+++I  +T   +  + N P PL  +
Sbjct: 673 ADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAM 732

Query: 775 TILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGG 834
            IL I++  D  PA SL  E  + D++++ PRN K   L    ++ +    I  I   G 
Sbjct: 733 QILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGT 790

Query: 835 FFTYFVILAENGFLP 849
            F ++  L +N   P
Sbjct: 791 LFVFWRELRDNVITP 805


>gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo
           sapiens]
          Length = 949

 Score =  372 bits (954), Expect = e-102
 Identities = 269/855 (31%), Positives = 419/855 (49%), Gaps = 96/855 (11%)

Query: 14  KLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSMLL 73
           +L + E+      DL  GL     +   A  G N        P W K+  Q      MLL
Sbjct: 28  ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87

Query: 74  WIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNM 133
              A++  L +    A             V ++  ++I    ++ QE +S K +E    +
Sbjct: 88  LASAVISVLMHQFDDA-------------VSITVAILIVVTVAFVQEYRSEKSLEELSKL 134

Query: 134 VPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEP 193
           VP +   +R G+     A ++V GD V +  GDR+PADLR+  A    +D SSLTGE+ P
Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194

Query: 194 QTR----SPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGG 249
            ++     P  TN +     NIAF  T    G A+G+V+ TG+ +  G +  +    E  
Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254

Query: 250 QTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWL------EAVIFLIGIIVANVPE 303
           +TP+   ++     + G  +    SF I+ +I+   WL      E     + + VA +PE
Sbjct: 255 KTPLQKSMD-----LLGKQLSF-YSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPE 308

Query: 304 GLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFD 363
           GL   VTV L L   RM +K  +VK L  VETLG  + ICSDKTGTLT+N MTV H++  
Sbjct: 309 GLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTS 368

Query: 364 NQIHEADTTE--NQSG---VSFDKTSATWL-ALSRI--AG-LCNRAVFQANQENLPILKR 414
           + +H   T    NQ G   V  D     +  A+SRI  AG +CN AV + N         
Sbjct: 369 DGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNN--------- 419

Query: 415 AVAGDASESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLL 474
            + G  +E AL+  + +  G +  +++ Y +  E PF+S  K+      +    +   + 
Sbjct: 420 TLMGKPTEGALI-ALAMKMG-LDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEIC 477

Query: 475 VMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQF 534
            MKGA E+++  C++    G+   L ++ +D +Q     +G  G RVL            
Sbjct: 478 FMKGAYEQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALA-------SG 530

Query: 535 PEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAK 594
           PE            +  L F+GL+ +IDPPR  V +AV    ++G+ + M+TGD   TA 
Sbjct: 531 PE------------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAV 578

Query: 595 AIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYH 654
           AIA  +G+ S+ +++V                         G ++  M  +QL  I+   
Sbjct: 579 AIASRLGLYSKTSQSVS------------------------GEEIDAMDVQQLSQIVP-- 612

Query: 655 TEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQA 714
              VF R SP+ K+ I++  Q+ G++VA+TGDGVND+ ALK ADIGVAMG  G+DV K+A
Sbjct: 613 KVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEA 672

Query: 715 ADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTV 774
           ADMIL+DD+F +I++ +EEG+ I++N+K  + + L+++I  +T   +  + N P PL  +
Sbjct: 673 ADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAM 732

Query: 775 TILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGG 834
            IL I++  D  PA SL  E  + D++++ PRN K   L    ++ +    I  I   G 
Sbjct: 733 QILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGT 790

Query: 835 FFTYFVILAENGFLP 849
            F ++  L +N   P
Sbjct: 791 LFVFWRELRDNVITP 805


>gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo
           sapiens]
          Length = 888

 Score =  372 bits (954), Expect = e-102
 Identities = 269/855 (31%), Positives = 419/855 (49%), Gaps = 96/855 (11%)

Query: 14  KLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSMLL 73
           +L + E+      DL  GL     +   A  G N        P W K+  Q      MLL
Sbjct: 28  ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87

Query: 74  WIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNM 133
              A++  L +    A             V ++  ++I    ++ QE +S K +E    +
Sbjct: 88  LASAVISVLMHQFDDA-------------VSITVAILIVVTVAFVQEYRSEKSLEELSKL 134

Query: 134 VPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEP 193
           VP +   +R G+     A ++V GD V +  GDR+PADLR+  A    +D SSLTGE+ P
Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194

Query: 194 QTR----SPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGG 249
            ++     P  TN +     NIAF  T    G A+G+V+ TG+ +  G +  +    E  
Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254

Query: 250 QTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWL------EAVIFLIGIIVANVPE 303
           +TP+   ++     + G  +    SF I+ +I+   WL      E     + + VA +PE
Sbjct: 255 KTPLQKSMD-----LLGKQLSF-YSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPE 308

Query: 304 GLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFD 363
           GL   VTV L L   RM +K  +VK L  VETLG  + ICSDKTGTLT+N MTV H++  
Sbjct: 309 GLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTS 368

Query: 364 NQIHEADTTE--NQSG---VSFDKTSATWL-ALSRI--AG-LCNRAVFQANQENLPILKR 414
           + +H   T    NQ G   V  D     +  A+SRI  AG +CN AV + N         
Sbjct: 369 DGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNN--------- 419

Query: 415 AVAGDASESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLL 474
            + G  +E AL+  + +  G +  +++ Y +  E PF+S  K+      +    +   + 
Sbjct: 420 TLMGKPTEGALI-ALAMKMG-LDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEIC 477

Query: 475 VMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQF 534
            MKGA E+++  C++    G+   L ++ +D +Q     +G  G RVL            
Sbjct: 478 FMKGAYEQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALA-------SG 530

Query: 535 PEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAK 594
           PE            +  L F+GL+ +IDPPR  V +AV    ++G+ + M+TGD   TA 
Sbjct: 531 PE------------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAV 578

Query: 595 AIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYH 654
           AIA  +G+ S+ +++V                         G ++  M  +QL  I+   
Sbjct: 579 AIASRLGLYSKTSQSVS------------------------GEEIDAMDVQQLSQIVP-- 612

Query: 655 TEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQA 714
              VF R SP+ K+ I++  Q+ G++VA+TGDGVND+ ALK ADIGVAMG  G+DV K+A
Sbjct: 613 KVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEA 672

Query: 715 ADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTV 774
           ADMIL+DD+F +I++ +EEG+ I++N+K  + + L+++I  +T   +  + N P PL  +
Sbjct: 673 ADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAM 732

Query: 775 TILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGG 834
            IL I++  D  PA SL  E  + D++++ PRN K   L    ++ +    I  I   G 
Sbjct: 733 QILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGT 790

Query: 835 FFTYFVILAENGFLP 849
            F ++  L +N   P
Sbjct: 791 LFVFWRELRDNVITP 805


>gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo
           sapiens]
          Length = 919

 Score =  372 bits (954), Expect = e-102
 Identities = 269/855 (31%), Positives = 419/855 (49%), Gaps = 96/855 (11%)

Query: 14  KLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSMLL 73
           +L + E+      DL  GL     +   A  G N        P W K+  Q      MLL
Sbjct: 28  ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87

Query: 74  WIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNM 133
              A++  L +    A             V ++  ++I    ++ QE +S K +E    +
Sbjct: 88  LASAVISVLMHQFDDA-------------VSITVAILIVVTVAFVQEYRSEKSLEELSKL 134

Query: 134 VPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEP 193
           VP +   +R G+     A ++V GD V +  GDR+PADLR+  A    +D SSLTGE+ P
Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194

Query: 194 QTR----SPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGG 249
            ++     P  TN +     NIAF  T    G A+G+V+ TG+ +  G +  +    E  
Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254

Query: 250 QTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWL------EAVIFLIGIIVANVPE 303
           +TP+   ++     + G  +    SF I+ +I+   WL      E     + + VA +PE
Sbjct: 255 KTPLQKSMD-----LLGKQLSF-YSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPE 308

Query: 304 GLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFD 363
           GL   VTV L L   RM +K  +VK L  VETLG  + ICSDKTGTLT+N MTV H++  
Sbjct: 309 GLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTS 368

Query: 364 NQIHEADTTE--NQSG---VSFDKTSATWL-ALSRI--AG-LCNRAVFQANQENLPILKR 414
           + +H   T    NQ G   V  D     +  A+SRI  AG +CN AV + N         
Sbjct: 369 DGLHAEVTGVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNN--------- 419

Query: 415 AVAGDASESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLL 474
            + G  +E AL+  + +  G +  +++ Y +  E PF+S  K+      +    +   + 
Sbjct: 420 TLMGKPTEGALI-ALAMKMG-LDGLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEIC 477

Query: 475 VMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQF 534
            MKGA E+++  C++    G+   L ++ +D +Q     +G  G RVL            
Sbjct: 478 FMKGAYEQVIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALA-------SG 530

Query: 535 PEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAK 594
           PE            +  L F+GL+ +IDPPR  V +AV    ++G+ + M+TGD   TA 
Sbjct: 531 PE------------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAV 578

Query: 595 AIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYH 654
           AIA  +G+ S+ +++V                         G ++  M  +QL  I+   
Sbjct: 579 AIASRLGLYSKTSQSVS------------------------GEEIDAMDVQQLSQIVP-- 612

Query: 655 TEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQA 714
              VF R SP+ K+ I++  Q+ G++VA+TGDGVND+ ALK ADIGVAMG  G+DV K+A
Sbjct: 613 KVAVFYRASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEA 672

Query: 715 ADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTV 774
           ADMIL+DD+F +I++ +EEG+ I++N+K  + + L+++I  +T   +  + N P PL  +
Sbjct: 673 ADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAM 732

Query: 775 TILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGG 834
            IL I++  D  PA SL  E  + D++++ PRN K   L    ++ +    I  I   G 
Sbjct: 733 QILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGT 790

Query: 835 FFTYFVILAENGFLP 849
            F ++  L +N   P
Sbjct: 791 LFVFWRELRDNVITP 805


>gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo
           sapiens]
          Length = 999

 Score =  369 bits (946), Expect = e-101
 Identities = 305/1036 (29%), Positives = 482/1036 (46%), Gaps = 120/1036 (11%)

Query: 13  HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSML 72
           H L   ++ R +      GL+ A+      R GPN L        W     Q       +
Sbjct: 5   HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64

Query: 73  LWIGAILCFLAYSIQAATEEEPQNDNLYLG-VVLSAVVIITGCFSYYQEAKSSKIMESFK 131
           L + A++ F    + A  EE  +    ++  +V+  +++       +QE  +   +E+ K
Sbjct: 65  LLLAALVSF----VLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120

Query: 132 NMVPQQALVIRNGEK--MSINAEEVVVGDLVEVKGGDRIPADLRIISANGC--KVDNSSL 187
              P+   VIR+  K    I A ++V GD+VEV  GD++PADLR+I       +VD S L
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180

Query: 188 TGESEPQTRS----PDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA 243
           TGES   T+     PD    N  + +N+ F  TN   G A G+ V TG  T +G+I +  
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQ-DKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQM 239

Query: 244 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSL------ILEYTWLEAVIFL---- 293
           + +E  +TP+  +++ F   ++     + V+ +++++          +WL   ++     
Sbjct: 240 AAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIA 299

Query: 294 IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 353
           + + VA +PEGL A +T CL L  +RMARKN +V++L +VETLG TS ICSDKTGTLT N
Sbjct: 300 VALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTN 359

Query: 354 RMTVAHMWFDNQ-------IHE---ADTTENQSGV-----------SFDKTSATWLALSR 392
           +M+V  M+   +       +HE   + TT    G             FD      + L+ 
Sbjct: 360 QMSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGL----VELAT 415

Query: 393 IAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIEL------------------CCG 434
           I  LCN +    N+      K    G+A+E+AL   +E                    C 
Sbjct: 416 ICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACN 472

Query: 435 SVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQ---HLLVMKGAPERILDRCSSIL 491
           +V +   R    +E    S ++  +S++  P    P      + +KGAPE +++RCSS+ 
Sbjct: 473 TVIKQLMRKEFTLEF---SRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVR 529

Query: 492 LHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDD----VNF 547
           +  +  PL    ++    A +   G G   L    L   D   P     + DD    V +
Sbjct: 530 VGSRTAPLTPTSREQIL-AKIRDWGSGSDTLRCLALATRDAP-PRKEDMELDDCSKFVQY 587

Query: 548 PIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGN 607
             D L FVG + M+DPPR  V   + +C  AGI+V+M+TGD+  TA AI + +GI  +  
Sbjct: 588 ETD-LTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD-- 644

Query: 608 ETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQK 667
              ED+A +                   G +  D++ EQ     +  T   FAR  P  K
Sbjct: 645 --TEDVAGK----------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHK 684

Query: 668 LIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASI 727
             IVE  Q    I A+TGDGVND+PALKKA+IG+AMG +G+ V+K AA+M+L DDNFASI
Sbjct: 685 SRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASI 743

Query: 728 VTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVP 787
           V  VEEGR I+ N+K+ I Y ++SN+ E+    +  I  +P  L  V +L ++L TD +P
Sbjct: 744 VAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLP 803

Query: 788 AISLAYEQAESDIMKRQPRNPKTDKLVNERLI--SMAYGQIGMIQALGGFFTYFVILAEN 845
           A +L +   + DIM++ PR+P+ + L++  L    +A G    +  +     +FV  AE 
Sbjct: 804 ATALGFNPPDLDIMEKLPRSPR-EALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEG 862

Query: 846 GFLPIHLLG--LRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADL 903
             +  + L   L+   D+     ++        +E R    F    A  V + +     L
Sbjct: 863 PHINFYQLRNFLKCSEDNPLFAGIDCE-----VFESR----FPTTMALSVLVTIEMCNAL 913

Query: 904 VICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPY 963
                 ++ +      N  L+  +    AL   +   P + +  ++ PL    W      
Sbjct: 914 NSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQI 973

Query: 964 SLLIFVYDEVRKLIIR 979
           SL + + DE  K + R
Sbjct: 974 SLPVILLDEALKYLSR 989


>gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
           sapiens]
          Length = 1029

 Score =  369 bits (946), Expect = e-101
 Identities = 305/1036 (29%), Positives = 482/1036 (46%), Gaps = 120/1036 (11%)

Query: 13  HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSML 72
           H L   ++ R +      GL+ A+      R GPN L        W     Q       +
Sbjct: 5   HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64

Query: 73  LWIGAILCFLAYSIQAATEEEPQNDNLYLG-VVLSAVVIITGCFSYYQEAKSSKIMESFK 131
           L + A++ F    + A  EE  +    ++  +V+  +++       +QE  +   +E+ K
Sbjct: 65  LLLAALVSF----VLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120

Query: 132 NMVPQQALVIRNGEK--MSINAEEVVVGDLVEVKGGDRIPADLRIISANGC--KVDNSSL 187
              P+   VIR+  K    I A ++V GD+VEV  GD++PADLR+I       +VD S L
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180

Query: 188 TGESEPQTRS----PDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA 243
           TGES   T+     PD    N  + +N+ F  TN   G A G+ V TG  T +G+I +  
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQ-DKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQM 239

Query: 244 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSL------ILEYTWLEAVIFL---- 293
           + +E  +TP+  +++ F   ++     + V+ +++++          +WL   ++     
Sbjct: 240 AAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIA 299

Query: 294 IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 353
           + + VA +PEGL A +T CL L  +RMARKN +V++L +VETLG TS ICSDKTGTLT N
Sbjct: 300 VALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTN 359

Query: 354 RMTVAHMWFDNQ-------IHE---ADTTENQSGV-----------SFDKTSATWLALSR 392
           +M+V  M+   +       +HE   + TT    G             FD      + L+ 
Sbjct: 360 QMSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGL----VELAT 415

Query: 393 IAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIEL------------------CCG 434
           I  LCN +    N+      K    G+A+E+AL   +E                    C 
Sbjct: 416 ICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACN 472

Query: 435 SVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQ---HLLVMKGAPERILDRCSSIL 491
           +V +   R    +E    S ++  +S++  P    P      + +KGAPE +++RCSS+ 
Sbjct: 473 TVIKQLMRKEFTLEF---SRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVR 529

Query: 492 LHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDD----VNF 547
           +  +  PL    ++    A +   G G   L    L   D   P     + DD    V +
Sbjct: 530 VGSRTAPLTPTSREQIL-AKIRDWGSGSDTLRCLALATRDAP-PRKEDMELDDCSKFVQY 587

Query: 548 PIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGN 607
             D L FVG + M+DPPR  V   + +C  AGI+V+M+TGD+  TA AI + +GI  +  
Sbjct: 588 ETD-LTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD-- 644

Query: 608 ETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQK 667
              ED+A +                   G +  D++ EQ     +  T   FAR  P  K
Sbjct: 645 --TEDVAGK----------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHK 684

Query: 668 LIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASI 727
             IVE  Q    I A+TGDGVND+PALKKA+IG+AMG +G+ V+K AA+M+L DDNFASI
Sbjct: 685 SRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASI 743

Query: 728 VTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVP 787
           V  VEEGR I+ N+K+ I Y ++SN+ E+    +  I  +P  L  V +L ++L TD +P
Sbjct: 744 VAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLP 803

Query: 788 AISLAYEQAESDIMKRQPRNPKTDKLVNERLI--SMAYGQIGMIQALGGFFTYFVILAEN 845
           A +L +   + DIM++ PR+P+ + L++  L    +A G    +  +     +FV  AE 
Sbjct: 804 ATALGFNPPDLDIMEKLPRSPR-EALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEG 862

Query: 846 GFLPIHLLG--LRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADL 903
             +  + L   L+   D+     ++        +E R    F    A  V + +     L
Sbjct: 863 PHINFYQLRNFLKCSEDNPLFAGIDCE-----VFESR----FPTTMALSVLVTIEMCNAL 913

Query: 904 VICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPY 963
                 ++ +      N  L+  +    AL   +   P + +  ++ PL    W      
Sbjct: 914 NSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQI 973

Query: 964 SLLIFVYDEVRKLIIR 979
           SL + + DE  K + R
Sbjct: 974 SLPVILLDEALKYLSR 989


>gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo
           sapiens]
          Length = 998

 Score =  369 bits (946), Expect = e-101
 Identities = 305/1036 (29%), Positives = 482/1036 (46%), Gaps = 120/1036 (11%)

Query: 13  HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSML 72
           H L   ++ R +      GL+ A+      R GPN L        W     Q       +
Sbjct: 5   HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64

Query: 73  LWIGAILCFLAYSIQAATEEEPQNDNLYLG-VVLSAVVIITGCFSYYQEAKSSKIMESFK 131
           L + A++ F    + A  EE  +    ++  +V+  +++       +QE  +   +E+ K
Sbjct: 65  LLLAALVSF----VLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120

Query: 132 NMVPQQALVIRNGEK--MSINAEEVVVGDLVEVKGGDRIPADLRIISANGC--KVDNSSL 187
              P+   VIR+  K    I A ++V GD+VEV  GD++PADLR+I       +VD S L
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180

Query: 188 TGESEPQTRS----PDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA 243
           TGES   T+     PD    N  + +N+ F  TN   G A G+ V TG  T +G+I +  
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQ-DKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQM 239

Query: 244 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSL------ILEYTWLEAVIFL---- 293
           + +E  +TP+  +++ F   ++     + V+ +++++          +WL   ++     
Sbjct: 240 AAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIA 299

Query: 294 IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 353
           + + VA +PEGL A +T CL L  +RMARKN +V++L +VETLG TS ICSDKTGTLT N
Sbjct: 300 VALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTN 359

Query: 354 RMTVAHMWFDNQ-------IHE---ADTTENQSGV-----------SFDKTSATWLALSR 392
           +M+V  M+   +       +HE   + TT    G             FD      + L+ 
Sbjct: 360 QMSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGL----VELAT 415

Query: 393 IAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIEL------------------CCG 434
           I  LCN +    N+      K    G+A+E+AL   +E                    C 
Sbjct: 416 ICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACN 472

Query: 435 SVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQ---HLLVMKGAPERILDRCSSIL 491
           +V +   R    +E    S ++  +S++  P    P      + +KGAPE +++RCSS+ 
Sbjct: 473 TVIKQLMRKEFTLEF---SRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVR 529

Query: 492 LHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDD----VNF 547
           +  +  PL    ++    A +   G G   L    L   D   P     + DD    V +
Sbjct: 530 VGSRTAPLTPTSREQIL-AKIRDWGSGSDTLRCLALATRDAP-PRKEDMELDDCSKFVQY 587

Query: 548 PIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGN 607
             D L FVG + M+DPPR  V   + +C  AGI+V+M+TGD+  TA AI + +GI  +  
Sbjct: 588 ETD-LTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD-- 644

Query: 608 ETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQK 667
              ED+A +                   G +  D++ EQ     +  T   FAR  P  K
Sbjct: 645 --TEDVAGK----------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHK 684

Query: 668 LIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASI 727
             IVE  Q    I A+TGDGVND+PALKKA+IG+AMG +G+ V+K AA+M+L DDNFASI
Sbjct: 685 SRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASI 743

Query: 728 VTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVP 787
           V  VEEGR I+ N+K+ I Y ++SN+ E+    +  I  +P  L  V +L ++L TD +P
Sbjct: 744 VAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLP 803

Query: 788 AISLAYEQAESDIMKRQPRNPKTDKLVNERLI--SMAYGQIGMIQALGGFFTYFVILAEN 845
           A +L +   + DIM++ PR+P+ + L++  L    +A G    +  +     +FV  AE 
Sbjct: 804 ATALGFNPPDLDIMEKLPRSPR-EALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEG 862

Query: 846 GFLPIHLLG--LRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADL 903
             +  + L   L+   D+     ++        +E R    F    A  V + +     L
Sbjct: 863 PHINFYQLRNFLKCSEDNPLFAGIDCE-----VFESR----FPTTMALSVLVTIEMCNAL 913

Query: 904 VICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPY 963
                 ++ +      N  L+  +    AL   +   P + +  ++ PL    W      
Sbjct: 914 NSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQI 973

Query: 964 SLLIFVYDEVRKLIIR 979
           SL + + DE  K + R
Sbjct: 974 SLPVILLDEALKYLSR 989


>gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
           sapiens]
          Length = 1029

 Score =  369 bits (946), Expect = e-101
 Identities = 305/1036 (29%), Positives = 482/1036 (46%), Gaps = 120/1036 (11%)

Query: 13  HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSML 72
           H L   ++ R +      GL+ A+      R GPN L        W     Q       +
Sbjct: 5   HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64

Query: 73  LWIGAILCFLAYSIQAATEEEPQNDNLYLG-VVLSAVVIITGCFSYYQEAKSSKIMESFK 131
           L + A++ F    + A  EE  +    ++  +V+  +++       +QE  +   +E+ K
Sbjct: 65  LLLAALVSF----VLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120

Query: 132 NMVPQQALVIRNGEK--MSINAEEVVVGDLVEVKGGDRIPADLRIISANGC--KVDNSSL 187
              P+   VIR+  K    I A ++V GD+VEV  GD++PADLR+I       +VD S L
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180

Query: 188 TGESEPQTRS----PDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA 243
           TGES   T+     PD    N  + +N+ F  TN   G A G+ V TG  T +G+I +  
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQ-DKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQM 239

Query: 244 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSL------ILEYTWLEAVIFL---- 293
           + +E  +TP+  +++ F   ++     + V+ +++++          +WL   ++     
Sbjct: 240 AAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIA 299

Query: 294 IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 353
           + + VA +PEGL A +T CL L  +RMARKN +V++L +VETLG TS ICSDKTGTLT N
Sbjct: 300 VALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTN 359

Query: 354 RMTVAHMWFDNQ-------IHE---ADTTENQSGV-----------SFDKTSATWLALSR 392
           +M+V  M+   +       +HE   + TT    G             FD      + L+ 
Sbjct: 360 QMSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGL----VELAT 415

Query: 393 IAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIEL------------------CCG 434
           I  LCN +    N+      K    G+A+E+AL   +E                    C 
Sbjct: 416 ICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACN 472

Query: 435 SVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQ---HLLVMKGAPERILDRCSSIL 491
           +V +   R    +E    S ++  +S++  P    P      + +KGAPE +++RCSS+ 
Sbjct: 473 TVIKQLMRKEFTLEF---SRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVR 529

Query: 492 LHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDD----VNF 547
           +  +  PL    ++    A +   G G   L    L   D   P     + DD    V +
Sbjct: 530 VGSRTAPLTPTSREQIL-AKIRDWGSGSDTLRCLALATRDAP-PRKEDMELDDCSKFVQY 587

Query: 548 PIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGN 607
             D L FVG + M+DPPR  V   + +C  AGI+V+M+TGD+  TA AI + +GI  +  
Sbjct: 588 ETD-LTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD-- 644

Query: 608 ETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQK 667
              ED+A +                   G +  D++ EQ     +  T   FAR  P  K
Sbjct: 645 --TEDVAGK----------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHK 684

Query: 668 LIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASI 727
             IVE  Q    I A+TGDGVND+PALKKA+IG+AMG +G+ V+K AA+M+L DDNFASI
Sbjct: 685 SRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASI 743

Query: 728 VTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVP 787
           V  VEEGR I+ N+K+ I Y ++SN+ E+    +  I  +P  L  V +L ++L TD +P
Sbjct: 744 VAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLP 803

Query: 788 AISLAYEQAESDIMKRQPRNPKTDKLVNERLI--SMAYGQIGMIQALGGFFTYFVILAEN 845
           A +L +   + DIM++ PR+P+ + L++  L    +A G    +  +     +FV  AE 
Sbjct: 804 ATALGFNPPDLDIMEKLPRSPR-EALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEG 862

Query: 846 GFLPIHLLG--LRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADL 903
             +  + L   L+   D+     ++        +E R    F    A  V + +     L
Sbjct: 863 PHINFYQLRNFLKCSEDNPLFAGIDCE-----VFESR----FPTTMALSVLVTIEMCNAL 913

Query: 904 VICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPY 963
                 ++ +      N  L+  +    AL   +   P + +  ++ PL    W      
Sbjct: 914 NSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQI 973

Query: 964 SLLIFVYDEVRKLIIR 979
           SL + + DE  K + R
Sbjct: 974 SLPVILLDEALKYLSR 989


>gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo
           sapiens]
          Length = 1043

 Score =  369 bits (946), Expect = e-101
 Identities = 305/1036 (29%), Positives = 482/1036 (46%), Gaps = 120/1036 (11%)

Query: 13  HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSML 72
           H L   ++ R +      GL+ A+      R GPN L        W     Q       +
Sbjct: 5   HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64

Query: 73  LWIGAILCFLAYSIQAATEEEPQNDNLYLG-VVLSAVVIITGCFSYYQEAKSSKIMESFK 131
           L + A++ F    + A  EE  +    ++  +V+  +++       +QE  +   +E+ K
Sbjct: 65  LLLAALVSF----VLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120

Query: 132 NMVPQQALVIRNGEK--MSINAEEVVVGDLVEVKGGDRIPADLRIISANGC--KVDNSSL 187
              P+   VIR+  K    I A ++V GD+VEV  GD++PADLR+I       +VD S L
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180

Query: 188 TGESEPQTRS----PDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA 243
           TGES   T+     PD    N  + +N+ F  TN   G A G+ V TG  T +G+I +  
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQ-DKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQM 239

Query: 244 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSL------ILEYTWLEAVIFL---- 293
           + +E  +TP+  +++ F   ++     + V+ +++++          +WL   ++     
Sbjct: 240 AAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIA 299

Query: 294 IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 353
           + + VA +PEGL A +T CL L  +RMARKN +V++L +VETLG TS ICSDKTGTLT N
Sbjct: 300 VALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTN 359

Query: 354 RMTVAHMWFDNQ-------IHE---ADTTENQSGV-----------SFDKTSATWLALSR 392
           +M+V  M+   +       +HE   + TT    G             FD      + L+ 
Sbjct: 360 QMSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGL----VELAT 415

Query: 393 IAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIEL------------------CCG 434
           I  LCN +    N+      K    G+A+E+AL   +E                    C 
Sbjct: 416 ICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACN 472

Query: 435 SVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQ---HLLVMKGAPERILDRCSSIL 491
           +V +   R    +E    S ++  +S++  P    P      + +KGAPE +++RCSS+ 
Sbjct: 473 TVIKQLMRKEFTLEF---SRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVR 529

Query: 492 LHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDD----VNF 547
           +  +  PL    ++    A +   G G   L    L   D   P     + DD    V +
Sbjct: 530 VGSRTAPLTPTSREQIL-AKIRDWGSGSDTLRCLALATRDAP-PRKEDMELDDCSKFVQY 587

Query: 548 PIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGN 607
             D L FVG + M+DPPR  V   + +C  AGI+V+M+TGD+  TA AI + +GI  +  
Sbjct: 588 ETD-LTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD-- 644

Query: 608 ETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQK 667
              ED+A +                   G +  D++ EQ     +  T   FAR  P  K
Sbjct: 645 --TEDVAGK----------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHK 684

Query: 668 LIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASI 727
             IVE  Q    I A+TGDGVND+PALKKA+IG+AMG +G+ V+K AA+M+L DDNFASI
Sbjct: 685 SRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASI 743

Query: 728 VTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVP 787
           V  VEEGR I+ N+K+ I Y ++SN+ E+    +  I  +P  L  V +L ++L TD +P
Sbjct: 744 VAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLP 803

Query: 788 AISLAYEQAESDIMKRQPRNPKTDKLVNERLI--SMAYGQIGMIQALGGFFTYFVILAEN 845
           A +L +   + DIM++ PR+P+ + L++  L    +A G    +  +     +FV  AE 
Sbjct: 804 ATALGFNPPDLDIMEKLPRSPR-EALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEG 862

Query: 846 GFLPIHLLG--LRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADL 903
             +  + L   L+   D+     ++        +E R    F    A  V + +     L
Sbjct: 863 PHINFYQLRNFLKCSEDNPLFAGIDCE-----VFESR----FPTTMALSVLVTIEMCNAL 913

Query: 904 VICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPY 963
                 ++ +      N  L+  +    AL   +   P + +  ++ PL    W      
Sbjct: 914 NSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQI 973

Query: 964 SLLIFVYDEVRKLIIR 979
           SL + + DE  K + R
Sbjct: 974 SLPVILLDEALKYLSR 989


>gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo
           sapiens]
          Length = 1044

 Score =  369 bits (946), Expect = e-101
 Identities = 305/1036 (29%), Positives = 482/1036 (46%), Gaps = 120/1036 (11%)

Query: 13  HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSML 72
           H L   ++ R +      GL+ A+      R GPN L        W     Q       +
Sbjct: 5   HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64

Query: 73  LWIGAILCFLAYSIQAATEEEPQNDNLYLG-VVLSAVVIITGCFSYYQEAKSSKIMESFK 131
           L + A++ F    + A  EE  +    ++  +V+  +++       +QE  +   +E+ K
Sbjct: 65  LLLAALVSF----VLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120

Query: 132 NMVPQQALVIRNGEK--MSINAEEVVVGDLVEVKGGDRIPADLRIISANGC--KVDNSSL 187
              P+   VIR+  K    I A ++V GD+VEV  GD++PADLR+I       +VD S L
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180

Query: 188 TGESEPQTRS----PDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA 243
           TGES   T+     PD    N  + +N+ F  TN   G A G+ V TG  T +G+I +  
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQ-DKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQM 239

Query: 244 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSL------ILEYTWLEAVIFL---- 293
           + +E  +TP+  +++ F   ++     + V+ +++++          +WL   ++     
Sbjct: 240 AAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIA 299

Query: 294 IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 353
           + + VA +PEGL A +T CL L  +RMARKN +V++L +VETLG TS ICSDKTGTLT N
Sbjct: 300 VALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTN 359

Query: 354 RMTVAHMWFDNQ-------IHE---ADTTENQSGV-----------SFDKTSATWLALSR 392
           +M+V  M+   +       +HE   + TT    G             FD      + L+ 
Sbjct: 360 QMSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGL----VELAT 415

Query: 393 IAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIEL------------------CCG 434
           I  LCN +    N+      K    G+A+E+AL   +E                    C 
Sbjct: 416 ICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACN 472

Query: 435 SVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQ---HLLVMKGAPERILDRCSSIL 491
           +V +   R    +E    S ++  +S++  P    P      + +KGAPE +++RCSS+ 
Sbjct: 473 TVIKQLMRKEFTLEF---SRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVR 529

Query: 492 LHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDD----VNF 547
           +  +  PL    ++    A +   G G   L    L   D   P     + DD    V +
Sbjct: 530 VGSRTAPLTPTSREQIL-AKIRDWGSGSDTLRCLALATRDAP-PRKEDMELDDCSKFVQY 587

Query: 548 PIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGN 607
             D L FVG + M+DPPR  V   + +C  AGI+V+M+TGD+  TA AI + +GI  +  
Sbjct: 588 ETD-LTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD-- 644

Query: 608 ETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQK 667
              ED+A +                   G +  D++ EQ     +  T   FAR  P  K
Sbjct: 645 --TEDVAGK----------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHK 684

Query: 668 LIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASI 727
             IVE  Q    I A+TGDGVND+PALKKA+IG+AMG +G+ V+K AA+M+L DDNFASI
Sbjct: 685 SRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASI 743

Query: 728 VTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVP 787
           V  VEEGR I+ N+K+ I Y ++SN+ E+    +  I  +P  L  V +L ++L TD +P
Sbjct: 744 VAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLP 803

Query: 788 AISLAYEQAESDIMKRQPRNPKTDKLVNERLI--SMAYGQIGMIQALGGFFTYFVILAEN 845
           A +L +   + DIM++ PR+P+ + L++  L    +A G    +  +     +FV  AE 
Sbjct: 804 ATALGFNPPDLDIMEKLPRSPR-EALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEG 862

Query: 846 GFLPIHLLG--LRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADL 903
             +  + L   L+   D+     ++        +E R    F    A  V + +     L
Sbjct: 863 PHINFYQLRNFLKCSEDNPLFAGIDCE-----VFESR----FPTTMALSVLVTIEMCNAL 913

Query: 904 VICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPY 963
                 ++ +      N  L+  +    AL   +   P + +  ++ PL    W      
Sbjct: 914 NSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQI 973

Query: 964 SLLIFVYDEVRKLIIR 979
           SL + + DE  K + R
Sbjct: 974 SLPVILLDEALKYLSR 989


>gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo
           sapiens]
          Length = 1052

 Score =  369 bits (946), Expect = e-101
 Identities = 305/1036 (29%), Positives = 482/1036 (46%), Gaps = 120/1036 (11%)

Query: 13  HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSML 72
           H L   ++ R +      GL+ A+      R GPN L        W     Q       +
Sbjct: 5   HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64

Query: 73  LWIGAILCFLAYSIQAATEEEPQNDNLYLG-VVLSAVVIITGCFSYYQEAKSSKIMESFK 131
           L + A++ F    + A  EE  +    ++  +V+  +++       +QE  +   +E+ K
Sbjct: 65  LLLAALVSF----VLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK 120

Query: 132 NMVPQQALVIRNGEK--MSINAEEVVVGDLVEVKGGDRIPADLRIISANGC--KVDNSSL 187
              P+   VIR+  K    I A ++V GD+VEV  GD++PADLR+I       +VD S L
Sbjct: 121 EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL 180

Query: 188 TGESEPQTRS----PDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA 243
           TGES   T+     PD    N  + +N+ F  TN   G A G+ V TG  T +G+I +  
Sbjct: 181 TGESVSVTKHTEAIPDPRAVNQ-DKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQM 239

Query: 244 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSL------ILEYTWLEAVIFL---- 293
           + +E  +TP+  +++ F   ++     + V+ +++++          +WL   ++     
Sbjct: 240 AAVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIA 299

Query: 294 IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 353
           + + VA +PEGL A +T CL L  +RMARKN +V++L +VETLG TS ICSDKTGTLT N
Sbjct: 300 VALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTN 359

Query: 354 RMTVAHMWFDNQ-------IHE---ADTTENQSGV-----------SFDKTSATWLALSR 392
           +M+V  M+   +       +HE   + TT    G             FD      + L+ 
Sbjct: 360 QMSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGL----VELAT 415

Query: 393 IAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIEL------------------CCG 434
           I  LCN +    N+      K    G+A+E+AL   +E                    C 
Sbjct: 416 ICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACN 472

Query: 435 SVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQ---HLLVMKGAPERILDRCSSIL 491
           +V +   R    +E    S ++  +S++  P    P      + +KGAPE +++RCSS+ 
Sbjct: 473 TVIKQLMRKEFTLEF---SRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVR 529

Query: 492 LHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDD----VNF 547
           +  +  PL    ++    A +   G G   L    L   D   P     + DD    V +
Sbjct: 530 VGSRTAPLTPTSREQIL-AKIRDWGSGSDTLRCLALATRDAP-PRKEDMELDDCSKFVQY 587

Query: 548 PIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGN 607
             D L FVG + M+DPPR  V   + +C  AGI+V+M+TGD+  TA AI + +GI  +  
Sbjct: 588 ETD-LTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD-- 644

Query: 608 ETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQK 667
              ED+A +                   G +  D++ EQ     +  T   FAR  P  K
Sbjct: 645 --TEDVAGK----------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHK 684

Query: 668 LIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASI 727
             IVE  Q    I A+TGDGVND+PALKKA+IG+AMG +G+ V+K AA+M+L DDNFASI
Sbjct: 685 SRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASI 743

Query: 728 VTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVP 787
           V  VEEGR I+ N+K+ I Y ++SN+ E+    +  I  +P  L  V +L ++L TD +P
Sbjct: 744 VAAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLP 803

Query: 788 AISLAYEQAESDIMKRQPRNPKTDKLVNERLI--SMAYGQIGMIQALGGFFTYFVILAEN 845
           A +L +   + DIM++ PR+P+ + L++  L    +A G    +  +     +FV  AE 
Sbjct: 804 ATALGFNPPDLDIMEKLPRSPR-EALISGWLFFRYLAIGVYVGLATVAAATWWFVYDAEG 862

Query: 846 GFLPIHLLG--LRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADL 903
             +  + L   L+   D+     ++        +E R    F    A  V + +     L
Sbjct: 863 PHINFYQLRNFLKCSEDNPLFAGIDCE-----VFESR----FPTTMALSVLVTIEMCNAL 913

Query: 904 VICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPY 963
                 ++ +      N  L+  +    AL   +   P + +  ++ PL    W      
Sbjct: 914 NSVSENQSLLRMPPWMNPWLLVAVAMSMALHFLILLVPPLPLIFQVTPLSGRQWVVVLQI 973

Query: 964 SLLIFVYDEVRKLIIR 979
           SL + + DE  K + R
Sbjct: 974 SLPVILLDEALKYLSR 989


>gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo
           sapiens]
          Length = 997

 Score =  357 bits (916), Expect = 3e-98
 Identities = 299/1036 (28%), Positives = 481/1036 (46%), Gaps = 121/1036 (11%)

Query: 13  HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSM- 71
           H  +++E+   +G + S GL+  +  ++  R G N L P       ++   + F    + 
Sbjct: 5   HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFEDLLVR 63

Query: 72  LLWIGAILCFLAYSIQAATEEEPQNDNLYLG-VVLSAVVIITGCFSYYQEAKSSKIMESF 130
           +L + A + F    + A  EE  +    ++   V+  +++       +QE  +   +E+ 
Sbjct: 64  ILLLAACISF----VLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEAL 119

Query: 131 KNMVPQQALVIRNGEK--MSINAEEVVVGDLVEVKGGDRIPADLRI--ISANGCKVDNSS 186
           K   P+   V R   K    I A+++V GD+VE+  GD++PAD+R+  I +   +VD S 
Sbjct: 120 KEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSI 179

Query: 187 LTGESEPQTRSPDFTNENPL---ETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA 243
           LTGES    +  D   +      + +N+ F  TN   G A G+VV TG  T +G+I    
Sbjct: 180 LTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEM 239

Query: 244 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSL------ILEYTWLEAVIFL---- 293
              E  +TP+  +++ F   ++ V   + ++ +I+++      +   +W+   I+     
Sbjct: 240 VATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIA 299

Query: 294 IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 353
           + + VA +PEGL A +T CL L  +RMA+KN +V++L +VETLG TS ICSDKTGTLT N
Sbjct: 300 VALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTN 359

Query: 354 RMTVAHMWFDNQIHEADTTENQSGVSFDKTSATW---------------------LALSR 392
           +M+V  M+  +++ E DT        F  T +T+                     + L+ 
Sbjct: 360 QMSVCRMFILDRV-EGDTCSLNE---FTITGSTYAPIGEVHKDDKPVNCHQYDGLVELAT 415

Query: 393 IAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIEL------------------CCG 434
           I  LCN +    N+      K    G+A+E+AL   +E                    C 
Sbjct: 416 ICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANACN 472

Query: 435 SVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHL--LVMKGAPERILDRCSSILL 492
           SV  +++   K   + F+   K  +S++  PN      +  + +KGAPE ++DRC+ I +
Sbjct: 473 SV--IKQLMKKEFTLEFSRDRK-SMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRV 529

Query: 493 HGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPI--D 550
              + P+   +K    +   E G  G   L    L   D           D  NF     
Sbjct: 530 GSTKVPMTSGVKQKIMSVIREWGS-GSDTLRCLALATHDNPLRREEMHLEDSANFIKYET 588

Query: 551 NLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETV 610
           NL FVG + M+DPPR  V  +V  CR AGI+VIM+TGD+  TA AI + +GI  +  +  
Sbjct: 589 NLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVT 648

Query: 611 EDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLII 670
               A       ++NP                 S Q D  L       FAR  P  K  I
Sbjct: 649 SK--AFTGREFDELNP-----------------SAQRDACLNARC---FARVEPSHKSKI 686

Query: 671 VEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTG 730
           VE  Q    I A+TGDGVND+PALKKA+IG+AMG +G+ V+K A++M+L DDNF++IV  
Sbjct: 687 VEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAA 745

Query: 731 VEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAIS 790
           VEEGR I++N+K+ I Y ++SN+ E+    +      P  L  V +L ++L TD +PA +
Sbjct: 746 VEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATA 805

Query: 791 LAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMI--QALGGFFTYFVILAENG-- 846
           L +   + DIM + PRNPK + L++  L    Y  IG     A  G   ++ I A+ G  
Sbjct: 806 LGFNPPDLDIMNKPPRNPK-EPLISGWLF-FRYLAIGCYVGAATVGAAAWWFIAADGGPR 863

Query: 847 ---FLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADL 903
              +   H L  + D  D     V+ +  +           +    A  V + +     L
Sbjct: 864 VSFYQLSHFLQCKEDNPD--FEGVDCAIFES---------PYPMTMALSVLVTIEMCNAL 912

Query: 904 VICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPY 963
                 ++ +     +N  L+  +    +L   + Y   + +  ++ PL  T W      
Sbjct: 913 NSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKI 972

Query: 964 SLLIFVYDEVRKLIIR 979
           SL + + DE  K + R
Sbjct: 973 SLPVILMDETLKFVAR 988


>gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1
           [Homo sapiens]
          Length = 1042

 Score =  357 bits (916), Expect = 3e-98
 Identities = 299/1036 (28%), Positives = 481/1036 (46%), Gaps = 121/1036 (11%)

Query: 13  HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSM- 71
           H  +++E+   +G + S GL+  +  ++  R G N L P       ++   + F    + 
Sbjct: 5   HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFEDLLVR 63

Query: 72  LLWIGAILCFLAYSIQAATEEEPQNDNLYLG-VVLSAVVIITGCFSYYQEAKSSKIMESF 130
           +L + A + F    + A  EE  +    ++   V+  +++       +QE  +   +E+ 
Sbjct: 64  ILLLAACISF----VLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEAL 119

Query: 131 KNMVPQQALVIRNGEK--MSINAEEVVVGDLVEVKGGDRIPADLRI--ISANGCKVDNSS 186
           K   P+   V R   K    I A+++V GD+VE+  GD++PAD+R+  I +   +VD S 
Sbjct: 120 KEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSI 179

Query: 187 LTGESEPQTRSPDFTNENPL---ETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA 243
           LTGES    +  D   +      + +N+ F  TN   G A G+VV TG  T +G+I    
Sbjct: 180 LTGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEM 239

Query: 244 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSL------ILEYTWLEAVIFL---- 293
              E  +TP+  +++ F   ++ V   + ++ +I+++      +   +W+   I+     
Sbjct: 240 VATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIA 299

Query: 294 IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 353
           + + VA +PEGL A +T CL L  +RMA+KN +V++L +VETLG TS ICSDKTGTLT N
Sbjct: 300 VALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTN 359

Query: 354 RMTVAHMWFDNQIHEADTTENQSGVSFDKTSATW---------------------LALSR 392
           +M+V  M+  +++ E DT        F  T +T+                     + L+ 
Sbjct: 360 QMSVCRMFILDRV-EGDTCSLNE---FTITGSTYAPIGEVHKDDKPVNCHQYDGLVELAT 415

Query: 393 IAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIEL------------------CCG 434
           I  LCN +    N+      K    G+A+E+AL   +E                    C 
Sbjct: 416 ICALCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANACN 472

Query: 435 SVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHL--LVMKGAPERILDRCSSILL 492
           SV  +++   K   + F+   K  +S++  PN      +  + +KGAPE ++DRC+ I +
Sbjct: 473 SV--IKQLMKKEFTLEFSRDRK-SMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRV 529

Query: 493 HGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPI--D 550
              + P+   +K    +   E G  G   L    L   D           D  NF     
Sbjct: 530 GSTKVPMTSGVKQKIMSVIREWGS-GSDTLRCLALATHDNPLRREEMHLEDSANFIKYET 588

Query: 551 NLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETV 610
           NL FVG + M+DPPR  V  +V  CR AGI+VIM+TGD+  TA AI + +GI  +  +  
Sbjct: 589 NLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVT 648

Query: 611 EDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLII 670
               A       ++NP                 S Q D  L       FAR  P  K  I
Sbjct: 649 SK--AFTGREFDELNP-----------------SAQRDACLNARC---FARVEPSHKSKI 686

Query: 671 VEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTG 730
           VE  Q    I A+TGDGVND+PALKKA+IG+AMG +G+ V+K A++M+L DDNF++IV  
Sbjct: 687 VEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAA 745

Query: 731 VEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAIS 790
           VEEGR I++N+K+ I Y ++SN+ E+    +      P  L  V +L ++L TD +PA +
Sbjct: 746 VEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATA 805

Query: 791 LAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMI--QALGGFFTYFVILAENG-- 846
           L +   + DIM + PRNPK + L++  L    Y  IG     A  G   ++ I A+ G  
Sbjct: 806 LGFNPPDLDIMNKPPRNPK-EPLISGWLF-FRYLAIGCYVGAATVGAAAWWFIAADGGPR 863

Query: 847 ---FLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADL 903
              +   H L  + D  D     V+ +  +           +    A  V + +     L
Sbjct: 864 VSFYQLSHFLQCKEDNPD--FEGVDCAIFES---------PYPMTMALSVLVTIEMCNAL 912

Query: 904 VICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPY 963
                 ++ +     +N  L+  +    +L   + Y   + +  ++ PL  T W      
Sbjct: 913 NSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKI 972

Query: 964 SLLIFVYDEVRKLIIR 979
           SL + + DE  K + R
Sbjct: 973 SLPVILMDETLKFVAR 988


>gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b
           [Homo sapiens]
          Length = 994

 Score =  355 bits (911), Expect = 1e-97
 Identities = 304/1047 (29%), Positives = 482/1047 (46%), Gaps = 142/1047 (13%)

Query: 13  HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSML 72
           H  + +E    +G   + GLT  +    L + G N L        W     Q       +
Sbjct: 5   HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 64

Query: 73  LWIGAILCFLAYSIQAATEEEPQNDNLYLG-VVLSAVVIITGCFSYYQEAKSSKIMESFK 131
           L + A + F    + A  EE  +    ++   V+  ++I       +QE  +   +E+ K
Sbjct: 65  LLLAACISF----VLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120

Query: 132 NMVPQQALVIRNGEK--MSINAEEVVVGDLVEVKGGDRIPADLRI--ISANGCKVDNSSL 187
              P+   V R   K    I A ++V GD+VEV  GD++PAD+RI  I +   +VD S L
Sbjct: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180

Query: 188 TGESEPQTRS----PDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA 243
           TGES    +     PD    N  + +N+ F  TN   G A GIV  TG  T +G+I    
Sbjct: 181 TGESVSVIKHTEPVPDPRAVNQ-DKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQM 239

Query: 244 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSL------ILEYTWLEAVIFL---- 293
           +  E  +TP+  +++ F   ++ V   + V+ +++++      +   +W    I+     
Sbjct: 240 AATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIA 299

Query: 294 IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 353
           + + VA +PEGL A +T CL L  +RMA+KN +V++L +VETLG TS ICSDKTGTLT N
Sbjct: 300 VALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTN 359

Query: 354 RMTVAHMWFDNQIH------------------EADTTENQSGVSFDKTSATWLALSRIAG 395
           +M+V  M+  +++                   E +  +N   V   +     + L+ I  
Sbjct: 360 QMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGL-VELATICA 418

Query: 396 LCNRAVFQANQENLPILKRAVAGDASESALLKCIEL------------------CCGSVK 437
           LCN +    N+      K    G+A+E+AL   +E                    C SV 
Sbjct: 419 LCNDSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSV- 474

Query: 438 EMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHL---LVMKGAPERILDRCSSILLHG 494
            +R+   K   + F+   K  +S++ +P  S    +   + +KGAPE ++DRC+ + +  
Sbjct: 475 -IRQLMKKEFTLEFSRDRK-SMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGT 532

Query: 495 KEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDD----VNFPID 550
              PL   +K+    A ++  G G   L    L   D   P+  +   DD    + +  D
Sbjct: 533 TRVPLTGPVKEKIM-AVIKEWGTGRDTLRCLALATRDTP-PKREEMVLDDSARFLEYETD 590

Query: 551 NLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETV 610
            L FVG++ M+DPPR  V  ++  CR AGI+VIM+TGD+  TA AI + +GI  E NE V
Sbjct: 591 -LTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGE-NEEV 648

Query: 611 EDIAARL----NIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQ 666
            D A       ++P+++      +AC                          FAR  P  
Sbjct: 649 ADRAYTGREFDDLPLAEQREACRRACC-------------------------FARVEPSH 683

Query: 667 KLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFAS 726
           K  IVE  Q    I A+TGDGVND+PALKKA+IG+AMG +G+ V+K A++M+L DDNF++
Sbjct: 684 KSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFST 742

Query: 727 IVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMV 786
           IV  VEEGR I++N+K+ I Y ++SN+ E+    +     +P  L  V +L ++L TD +
Sbjct: 743 IVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGL 802

Query: 787 PAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENG 846
           PA +L +   + DIM R PR+PK      E LIS      G +     FF Y  I    G
Sbjct: 803 PATALGFNPPDLDIMDRPPRSPK------EPLIS------GWL-----FFRYMAI---GG 842

Query: 847 FLPIHLLGLRVDW-----DDRWINDVEDSYGQQWTYEQRKIVEFTCH--------TAFFV 893
           ++    +G    W     D   +N  + ++  Q T +        C         T    
Sbjct: 843 YVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALS 902

Query: 894 SIVVVQWADLVICKTRRNSVFQQGMKNKILIFG-LFEETALAAFLSYCPGMGVALRMYPL 952
            +V ++  + +   +   S+ +      I + G +    +L   + Y   + +  ++  L
Sbjct: 903 VLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRAL 962

Query: 953 KPTWWFCAFPYSLLIFVYDEVRKLIIR 979
             T W      SL +   DE+ K + R
Sbjct: 963 DLTQWLMVLKISLPVIGLDEILKFVAR 989


>gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a
           [Homo sapiens]
          Length = 1001

 Score =  355 bits (911), Expect = 1e-97
 Identities = 304/1047 (29%), Positives = 482/1047 (46%), Gaps = 142/1047 (13%)

Query: 13  HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSML 72
           H  + +E    +G   + GLT  +    L + G N L        W     Q       +
Sbjct: 5   HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 64

Query: 73  LWIGAILCFLAYSIQAATEEEPQNDNLYLG-VVLSAVVIITGCFSYYQEAKSSKIMESFK 131
           L + A + F    + A  EE  +    ++   V+  ++I       +QE  +   +E+ K
Sbjct: 65  LLLAACISF----VLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK 120

Query: 132 NMVPQQALVIRNGEK--MSINAEEVVVGDLVEVKGGDRIPADLRI--ISANGCKVDNSSL 187
              P+   V R   K    I A ++V GD+VEV  GD++PAD+RI  I +   +VD S L
Sbjct: 121 EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSIL 180

Query: 188 TGESEPQTRS----PDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA 243
           TGES    +     PD    N  + +N+ F  TN   G A GIV  TG  T +G+I    
Sbjct: 181 TGESVSVIKHTEPVPDPRAVNQ-DKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQM 239

Query: 244 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSL------ILEYTWLEAVIFL---- 293
           +  E  +TP+  +++ F   ++ V   + V+ +++++      +   +W    I+     
Sbjct: 240 AATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIA 299

Query: 294 IGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQN 353
           + + VA +PEGL A +T CL L  +RMA+KN +V++L +VETLG TS ICSDKTGTLT N
Sbjct: 300 VALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTN 359

Query: 354 RMTVAHMWFDNQIH------------------EADTTENQSGVSFDKTSATWLALSRIAG 395
           +M+V  M+  +++                   E +  +N   V   +     + L+ I  
Sbjct: 360 QMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGL-VELATICA 418

Query: 396 LCNRAVFQANQENLPILKRAVAGDASESALLKCIEL------------------CCGSVK 437
           LCN +    N+      K    G+A+E+AL   +E                    C SV 
Sbjct: 419 LCNDSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSV- 474

Query: 438 EMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHL---LVMKGAPERILDRCSSILLHG 494
            +R+   K   + F+   K  +S++ +P  S    +   + +KGAPE ++DRC+ + +  
Sbjct: 475 -IRQLMKKEFTLEFSRDRK-SMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGT 532

Query: 495 KEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDD----VNFPID 550
              PL   +K+    A ++  G G   L    L   D   P+  +   DD    + +  D
Sbjct: 533 TRVPLTGPVKEKIM-AVIKEWGTGRDTLRCLALATRDTP-PKREEMVLDDSARFLEYETD 590

Query: 551 NLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETV 610
            L FVG++ M+DPPR  V  ++  CR AGI+VIM+TGD+  TA AI + +GI  E NE V
Sbjct: 591 -LTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGE-NEEV 648

Query: 611 EDIAARL----NIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQ 666
            D A       ++P+++      +AC                          FAR  P  
Sbjct: 649 ADRAYTGREFDDLPLAEQREACRRACC-------------------------FARVEPSH 683

Query: 667 KLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFAS 726
           K  IVE  Q    I A+TGDGVND+PALKKA+IG+AMG +G+ V+K A++M+L DDNF++
Sbjct: 684 KSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFST 742

Query: 727 IVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMV 786
           IV  VEEGR I++N+K+ I Y ++SN+ E+    +     +P  L  V +L ++L TD +
Sbjct: 743 IVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGL 802

Query: 787 PAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENG 846
           PA +L +   + DIM R PR+PK      E LIS      G +     FF Y  I    G
Sbjct: 803 PATALGFNPPDLDIMDRPPRSPK------EPLIS------GWL-----FFRYMAI---GG 842

Query: 847 FLPIHLLGLRVDW-----DDRWINDVEDSYGQQWTYEQRKIVEFTCH--------TAFFV 893
           ++    +G    W     D   +N  + ++  Q T +        C         T    
Sbjct: 843 YVGAATVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALS 902

Query: 894 SIVVVQWADLVICKTRRNSVFQQGMKNKILIFG-LFEETALAAFLSYCPGMGVALRMYPL 952
            +V ++  + +   +   S+ +      I + G +    +L   + Y   + +  ++  L
Sbjct: 903 VLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRAL 962

Query: 953 KPTWWFCAFPYSLLIFVYDEVRKLIIR 979
             T W      SL +   DE+ K + R
Sbjct: 963 DLTQWLMVLKISLPVIGLDEILKFVAR 989


>gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo
           sapiens]
          Length = 946

 Score =  353 bits (905), Expect = 6e-97
 Identities = 264/822 (32%), Positives = 401/822 (48%), Gaps = 90/822 (10%)

Query: 14  KLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSMLL 73
           K   ++L R +  DL  GL+     +     G N      + P W K+  Q      +LL
Sbjct: 59  KCQKEDLARAFCVDLHTGLSEFSVTQRRLAHGWNEFVADNSEPVWKKYLDQFKNPLILLL 118

Query: 74  WIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNM 133
              A++  L    + A             V ++  V++    ++ QE +S K +E    M
Sbjct: 119 LGSALVSVLTKEYEDA-------------VSIATAVLVVVTVAFIQEYRSEKSLEELTKM 165

Query: 134 VPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEP 193
           VP +   +R G+   + A E+V GD+V +  GDRIPAD+R+       VD SS TGE+EP
Sbjct: 166 VPPECNCLREGKLQHLLARELVPGDVVSLSIGDRIPADIRLTEVTDLLVDESSFTGEAEP 225

Query: 194 --QTRSPDFTNENPLET-RNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQ 250
             +T SP  T    L T  NI F  T    G  +G+V+ TG+ +  G +  +    E  +
Sbjct: 226 CSKTDSP-LTGGGDLTTLSNIVFMGTLVQYGRGQGVVIGTGESSQFGEVFKMMQAEETPK 284

Query: 251 TPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAV----IFLIGI--IVANVPEG 304
           TP+   ++     +T   +F   SF I+ LI+   W +      +F IG+   VA +PEG
Sbjct: 285 TPLQKSMDRLGKQLT---LF---SFGIIGLIMLIGWSQGKQLLSMFTIGVSLAVAAIPEG 338

Query: 305 LLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDN 364
           L   V V L L   RMA+K  +VK L  VETLG  S +CSDKTGTLT N MTV  +   +
Sbjct: 339 LPIVVMVTLVLGVLRMAKKRVIVKKLPIVETLGCCSVLCSDKTGTLTANEMTVTQLVTSD 398

Query: 365 QIHEADTTENQSGVSFDKTSATWLALSR--IAGLCNRAVFQANQ-----ENLPILKRAVA 417
            +         SGV +D      L  S+  I    N +V +  +      N  I K AV 
Sbjct: 399 GLRA-----EVSGVGYDGQGTVCLLPSKEVIKEFSNVSVGKLVEAGCVANNAVIRKNAVM 453

Query: 418 GDASESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMK 477
           G  +E AL+         + +++  Y +  EIPF+S  K+ +++  +  T + + +  MK
Sbjct: 454 GQPTEGALMALAMKM--DLSDIKNSYIRKKEIPFSSEQKW-MAVKCSLKTEDQEDIYFMK 510

Query: 478 GAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEG 537
           GA E ++  C+     G   PL  + +         +G LG RVL            PE 
Sbjct: 511 GALEEVIRYCTMYNNGGIPLPLTPQQRSFCLQEEKRMGSLGLRVLALA-------SGPE- 562

Query: 538 FQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIA 597
                      +  L F+GL+ +IDPPR  V +AV     +G+ V M+TGD   TA AI 
Sbjct: 563 -----------LGRLTFLGLVGIIDPPRVGVKEAVQVLSESGVSVKMITGDALETALAIG 611

Query: 598 KGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEI 657
           + +G+ +                         K   + G ++  +   +L D  +     
Sbjct: 612 RNIGLCN------------------------GKLQAMSGEEVDSVEKGELAD--RVGKVS 645

Query: 658 VFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADM 717
           VF RTSP+ KL I++  Q  GAIVA+TGDGVND+ ALK ADIG+AMG  G+DVSK+AA+M
Sbjct: 646 VFFRTSPKHKLKIIKALQESGAIVAMTGDGVNDAVALKSADIGIAMGQTGTDVSKEAANM 705

Query: 718 ILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTIL 777
           IL+DD+F++I+  VEEG+ IF N+K  + + L+++I  ++   +  + N+P PL  + IL
Sbjct: 706 ILVDDDFSAIMNAVEEGKGIFYNIKNFVRFQLSTSISALSLITLSTVFNLPSPLNAMQIL 765

Query: 778 CIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLI 819
            I++  D  PA SL  E  + D  ++ PR+ + D +++  LI
Sbjct: 766 WINIIMDGPPAQSLGVEPVDKDAFRQPPRSVR-DTILSRALI 806


>gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3
           [Homo sapiens]
          Length = 1015

 Score =  330 bits (845), Expect = 5e-90
 Identities = 288/1031 (27%), Positives = 468/1031 (45%), Gaps = 138/1031 (13%)

Query: 13  HKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSM- 71
           H  +++E+   +G + S GL+  +  ++  R G N L P       ++   + F    + 
Sbjct: 5   HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFEDLLVR 63

Query: 72  LLWIGAILCFLAYSIQAATEEEPQNDNLYLG-VVLSAVVIITGCFSYYQEAKSSKIMESF 130
           +L + A + F    + A  EE  +    ++   V+  +++       +QE  +   +E+ 
Sbjct: 64  ILLLAACISF----VLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEAL 119

Query: 131 KNMVPQQALVIRNGEK--MSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLT 188
           K   P+   V R   K    I A+++V GD+VE+ G                  ++ S+ 
Sbjct: 120 KEYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAG------------------ESVSVI 161

Query: 189 GESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEG 248
             ++P    P   N+   + +N+ F  TN   G A G+VV TG  T +G+I       E 
Sbjct: 162 KHTDP-VPDPRAVNQ---DKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQ 217

Query: 249 GQTPIAAEIEHFIHIITGVAVFLGVSFFILSL------ILEYTWLEAVIFL----IGIIV 298
            +TP+  +++ F   ++ V   + ++ +I+++      +   +W+   I+     + + V
Sbjct: 218 ERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAV 277

Query: 299 ANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVA 358
           A +PEGL A +T CL L  +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M+V 
Sbjct: 278 AAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVC 337

Query: 359 HMWFDNQIHEADTTENQSGVSFDKTSATW---------------------LALSRIAGLC 397
            M+  +++ E DT        F  T +T+                     + L+ I  LC
Sbjct: 338 RMFILDRV-EGDTCSLNE---FTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC 393

Query: 398 NRAVFQANQENLPILKRAVAGDASESALLKCIEL------------------CCGSVKEM 439
           N +    N+      K    G+A+E+AL   +E                    C SV  +
Sbjct: 394 NDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANACNSV--I 448

Query: 440 RERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHL--LVMKGAPERILDRCSSILLHGKEQ 497
           ++   K   + F+   K  +S++  PN      +  + +KGAPE ++DRC+ I +   + 
Sbjct: 449 KQLMKKEFTLEFSRDRK-SMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKV 507

Query: 498 PLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPI--DNLCFV 555
           P+   +K    +   E G  G   L    L   D           D  NF     NL FV
Sbjct: 508 PMTSGVKQKIMSVIREWGS-GSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFV 566

Query: 556 GLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAA 615
           G + M+DPPR  V  +V  CR AGI+VIM+TGD+  TA AI + +GI  +  +      A
Sbjct: 567 GCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSK--A 624

Query: 616 RLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGCQ 675
                  ++NP                 S Q D  L       FAR  P  K  IVE  Q
Sbjct: 625 FTGREFDELNP-----------------SAQRDACLNARC---FARVEPSHKSKIVEFLQ 664

Query: 676 RQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGR 735
               I A+TGDGVND+PALKKA+IG+AMG +G+ V+K A++M+L DDNF++IV  VEEGR
Sbjct: 665 SFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGR 723

Query: 736 LIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQ 795
            I++N+K+ I Y ++SN+ E+    +      P  L  V +L ++L TD +PA +L +  
Sbjct: 724 AIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNP 783

Query: 796 AESDIMKRQPRNPKTDKLVNERLISMAYGQIGMI--QALGGFFTYFVILAENG-----FL 848
            + DIM + PRNPK + L++  L    Y  IG     A  G   ++ I A+ G     + 
Sbjct: 784 PDLDIMNKPPRNPK-EPLISGWLF-FRYLAIGCYVGAATVGAAAWWFIAADGGPRVSFYQ 841

Query: 849 PIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKT 908
             H L  + D  D     V+ +  +           +    A  V + +     L     
Sbjct: 842 LSHFLQCKEDNPD--FEGVDCAIFES---------PYPMTMALSVLVTIEMCNALNSLSE 890

Query: 909 RRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIF 968
            ++ +     +N  L+  +    +L   + Y   + +  ++ PL  T W      SL + 
Sbjct: 891 NQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITPLNVTQWLMVLKISLPVI 950

Query: 969 VYDEVRKLIIR 979
           + DE  K + R
Sbjct: 951 LMDETLKFVAR 961


>gi|49249977 Na+/K+ -ATPase alpha 4 subunit isoform 2 [Homo sapiens]
          Length = 165

 Score =  288 bits (738), Expect = 1e-77
 Identities = 130/165 (78%), Positives = 150/165 (90%)

Query: 828 MIQALGGFFTYFVILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTC 887
           MIQAL GFFTYFVILAENGF P+ LLG+R+ W+D+++ND+EDSYGQQWTYEQRK+VEFTC
Sbjct: 1   MIQALAGFFTYFVILAENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTC 60

Query: 888 HTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVAL 947
            TAFFV+IVVVQWADL+I KTRRNS+FQQGM+NK+LIFG+ EET LAAFLSY PGM VAL
Sbjct: 61  QTAFFVTIVVVQWADLIISKTRRNSLFQQGMRNKVLIFGILEETLLAAFLSYTPGMDVAL 120

Query: 948 RMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 992
           RMYPLK TWW CA PYS+LIFVYDE+RKL+IR+ P GWVE+ETYY
Sbjct: 121 RMYPLKITWWLCAIPYSILIFVYDEIRKLLIRQHPDGWVERETYY 165


>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo
           sapiens]
          Length = 1198

 Score =  273 bits (697), Expect = 8e-73
 Identities = 245/838 (29%), Positives = 394/838 (47%), Gaps = 143/838 (17%)

Query: 87  QAATEEEPQNDNLYL---GVVLSAV-VIITGCFSYYQEAKSSKIMESFKNMVPQQALVIR 142
           Q   E+E + +  ++    ++LS + V++   F+ + + K  + ++S +    Q+  V+R
Sbjct: 138 QGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVVR 196

Query: 143 NGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTN 202
            G+ + I   E+VVGD+ +VK GD +PAD   I  N  K+D SSLTGES+   +S D   
Sbjct: 197 AGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVD--- 253

Query: 203 ENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA------------------- 243
           ++P+         T+ +EG+ R +V   G  +  G I TL                    
Sbjct: 254 KDPM-----LLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDG 308

Query: 244 ------------------------------SGLEGGQTPIAAEIEHFIHIITGVAVFLGV 273
                                         S L+G  T +A +I     +++ + V + V
Sbjct: 309 AAAMEMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILV 368

Query: 274 SFFILS--LILEYTWLEAV----------IFLIGI--IVANVPEGLLATVTVCLTLTAKR 319
            +F +   ++ +  WL              F+IG+  +V  VPEGL   VT+ L  + K+
Sbjct: 369 LYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKK 428

Query: 320 MARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVS 379
           M + N LV++L+A ET+G+ + ICSDKTGTLT NRMTV   +  + +H  +  +  S   
Sbjct: 429 MMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGD-VHYKEIPDPSS--- 484

Query: 380 FDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEM 439
              T    L ++ IA            E    L R V G+ +E  LL       G V ++
Sbjct: 485 -INTKTMELLINAIAINSAYTTKILPPEKEGALPRQV-GNKTECGLL-------GFVLDL 535

Query: 440 RERYAKI-VEIP---------FNSTNKYQLSIHKNPNTSEPQHLLVMKGAPERILDRCSS 489
           ++ Y  +  ++P         FNS  K   ++ K P+ S     +  KGA E +L +C  
Sbjct: 536 KQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDES---FRMYSKGASEIVLKKCCK 592

Query: 490 ILLHGKEQPL-------DEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQFDT 542
           IL +G  +P        DE +K   +    +         G   + +    FP   + D 
Sbjct: 593 IL-NGAGEPRVFRPRDRDEMVKKVIEPMACD---------GLRTICVAYRDFPSSPEPDW 642

Query: 543 DDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGI 602
           D+ N  ++ L  + ++ + DP R  VP+A+ KC+ AGI V MVTGD+  TA+AIA   GI
Sbjct: 643 DNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGI 702

Query: 603 ISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFART 662
           I  G +        L +   + N R         ++  ++  E++D I  +    V AR+
Sbjct: 703 IHPGEDF-------LCLEGKEFNRRIR-------NEKGEIEQERIDKI--WPKLRVLARS 746

Query: 663 SPQQKLIIVEGC-----QRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADM 717
           SP  K  +V+G        Q  +VAVTGDG ND PALKKAD+G AMGIAG+DV+K+A+D+
Sbjct: 747 SPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDI 806

Query: 718 ILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTIL 777
           IL DDNF+SIV  V  GR ++D++ K + + LT N+  +             PL  V +L
Sbjct: 807 ILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQML 866

Query: 778 CIDLGTDMVPAISLAYEQAESDIMKRQP---RNPKTDKLVNERLISMAYGQIGMIQAL 832
            ++L  D   +++LA E     ++ R+P     P   + + + ++  A  Q+ +I  L
Sbjct: 867 WVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFTL 924


>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
           sapiens]
          Length = 1170

 Score =  237 bits (605), Expect = 4e-62
 Identities = 192/622 (30%), Positives = 303/622 (48%), Gaps = 76/622 (12%)

Query: 244 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILS--LILEYTWLEAV----------I 291
           S L+G  T +A +I     +++ + VF+ + +F++   +I    WL              
Sbjct: 350 SVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKF 409

Query: 292 FLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 349
           F+IGI  +V  VPEGL   VT+ L  + K+M + N LV++L+A ET+G+ + ICSDKTGT
Sbjct: 410 FIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 469

Query: 350 LTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENL 409
           LT NRMTV   +               G+ + +  +  + L ++  L    +   +    
Sbjct: 470 LTMNRMTVVQAYI-------------GGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTS 516

Query: 410 PILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIV-EIP---------FNSTNKYQL 459
            IL     G        K      G V ++++ Y  +  E+P         FNS  K   
Sbjct: 517 KILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMS 576

Query: 460 SIHKNPNTSEPQHLLVMKGAPERILDRCSSIL-LHGKEQPLDEELKDAFQNAYLE-LGGL 517
           ++ +NPN       +  KGA E IL +C+ IL   G+  P   + +D      +E +   
Sbjct: 577 TVIRNPNGG---FRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACD 633

Query: 518 GERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRS 577
           G R +   +    D +         D+ N  +  L  + ++ + DP R  VPDA+ KC+ 
Sbjct: 634 GLRTICIAYRDFDDTEP------SWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKCKQ 687

Query: 578 AGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGS 637
           AGI V MVTGD+  TA+AIA   GI++ G++ +       N  +     R+ K       
Sbjct: 688 AGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLI-----RNEKG------ 736

Query: 638 DLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGC-------QRQGAIVAVTGDGVND 690
              ++  E+LD I  +    V AR+SP  K  +V+G         RQ  +VAVTGDG ND
Sbjct: 737 ---EVEQEKLDKI--WPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQ--VVAVTGDGTND 789

Query: 691 SPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLT 750
            PALKKAD+G AMGIAG+DV+K+A+D+IL DDNF SIV  V  GR ++D++ K + + LT
Sbjct: 790 GPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLT 849

Query: 751 SNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQP---RN 807
            N+  +             PL  V +L ++L  D   +++LA E     ++KR+P     
Sbjct: 850 VNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNK 909

Query: 808 PKTDKLVNERLISMAYGQIGMI 829
           P   + + + ++  A+ Q+ +I
Sbjct: 910 PLISRTMMKNILGHAFYQLIVI 931



 Score = 71.2 bits (173), Expect = 4e-12
 Identities = 51/161 (31%), Positives = 80/161 (49%), Gaps = 13/161 (8%)

Query: 87  QAATEEEPQND---NLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQAL--VI 141
           Q AT  E +N+       G  +   VII    + + +    K     +  + Q+    +I
Sbjct: 134 QVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSII 193

Query: 142 RNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFT 201
           RNG+ + +   E+VVGD+ +VK GD +PAD  +I  N  K+D SSLTGES+   +S D  
Sbjct: 194 RNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLD-- 251

Query: 202 NENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATL 242
            ++P+         T+ +EG+ R +V   G  +  G I TL
Sbjct: 252 -KDPM-----LLSGTHVMEGSGRMVVTAVGVNSQTGIILTL 286


>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
           sapiens]
          Length = 1205

 Score =  237 bits (605), Expect = 4e-62
 Identities = 192/622 (30%), Positives = 303/622 (48%), Gaps = 76/622 (12%)

Query: 244 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILS--LILEYTWLEAV----------I 291
           S L+G  T +A +I     +++ + VF+ + +F++   +I    WL              
Sbjct: 350 SVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDNFVINRRPWLPECTPIYIQYFVKF 409

Query: 292 FLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 349
           F+IGI  +V  VPEGL   VT+ L  + K+M + N LV++L+A ET+G+ + ICSDKTGT
Sbjct: 410 FIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 469

Query: 350 LTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENL 409
           LT NRMTV   +               G+ + +  +  + L ++  L    +   +    
Sbjct: 470 LTMNRMTVVQAYI-------------GGIHYRQIPSPDVFLPKVLDLIVNGISINSAYTS 516

Query: 410 PILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIV-EIP---------FNSTNKYQL 459
            IL     G        K      G V ++++ Y  +  E+P         FNS  K   
Sbjct: 517 KILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNEVPEEKLYKVYTFNSVRKSMS 576

Query: 460 SIHKNPNTSEPQHLLVMKGAPERILDRCSSIL-LHGKEQPLDEELKDAFQNAYLE-LGGL 517
           ++ +NPN       +  KGA E IL +C+ IL   G+  P   + +D      +E +   
Sbjct: 577 TVIRNPNGG---FRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACD 633

Query: 518 GERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRS 577
           G R +   +    D +         D+ N  +  L  + ++ + DP R  VPDA+ KC+ 
Sbjct: 634 GLRTICIAYRDFDDTEP------SWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKCKQ 687

Query: 578 AGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGS 637
           AGI V MVTGD+  TA+AIA   GI++ G++ +       N  +     R+ K       
Sbjct: 688 AGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLI-----RNEKG------ 736

Query: 638 DLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGC-------QRQGAIVAVTGDGVND 690
              ++  E+LD I  +    V AR+SP  K  +V+G         RQ  +VAVTGDG ND
Sbjct: 737 ---EVEQEKLDKI--WPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQ--VVAVTGDGTND 789

Query: 691 SPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLT 750
            PALKKAD+G AMGIAG+DV+K+A+D+IL DDNF SIV  V  GR ++D++ K + + LT
Sbjct: 790 GPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLT 849

Query: 751 SNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQP---RN 807
            N+  +             PL  V +L ++L  D   +++LA E     ++KR+P     
Sbjct: 850 VNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNK 909

Query: 808 PKTDKLVNERLISMAYGQIGMI 829
           P   + + + ++  A+ Q+ +I
Sbjct: 910 PLISRTMMKNILGHAFYQLIVI 931



 Score = 71.2 bits (173), Expect = 4e-12
 Identities = 51/161 (31%), Positives = 80/161 (49%), Gaps = 13/161 (8%)

Query: 87  QAATEEEPQND---NLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQAL--VI 141
           Q AT  E +N+       G  +   VII    + + +    K     +  + Q+    +I
Sbjct: 134 QVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSII 193

Query: 142 RNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFT 201
           RNG+ + +   E+VVGD+ +VK GD +PAD  +I  N  K+D SSLTGES+   +S D  
Sbjct: 194 RNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLD-- 251

Query: 202 NENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATL 242
            ++P+         T+ +EG+ R +V   G  +  G I TL
Sbjct: 252 -KDPM-----LLSGTHVMEGSGRMVVTAVGVNSQTGIILTL 286


>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
           sapiens]
          Length = 1176

 Score =  236 bits (602), Expect = 8e-62
 Identities = 197/632 (31%), Positives = 313/632 (49%), Gaps = 88/632 (13%)

Query: 244 SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSL--ILEYTWLEAV----------I 291
           S L+G  T +A +I     +++ + V + V +F++    + +  WL              
Sbjct: 360 SVLQGKLTKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKF 419

Query: 292 FLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 349
           F+IG+  +V  VPEGL   VT+ L  + K+M + N LV++L+A ET+G+ + ICSDKTGT
Sbjct: 420 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 479

Query: 350 LTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENL 409
           LT NRMTV   +  N+ H     E ++ +  +  S     +S      ++ +    +  L
Sbjct: 480 LTMNRMTVVQAYI-NEKHYKKVPEPEA-IPPNILSYLVTGISVNCAYTSKILPPEKEGGL 537

Query: 410 PILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIV-EIP---------FNSTNKYQL 459
           P       G+ +E ALL       G + +++  Y  +  EIP         FNS  K   
Sbjct: 538 P----RHVGNKTECALL-------GLLLDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMS 586

Query: 460 SIHKNPNTSEPQHLLVMKGAPERILDRCSSILLHGKE----QPLDEELKDAFQNAYLELG 515
           ++ KN   S+  + +  KGA E IL +C  IL    E    +P D +  D  +     + 
Sbjct: 587 TVLKN---SDGSYRIFSKGASEIILKKCFKILSANGEAKVFRPRDRD--DIVKTVIEPMA 641

Query: 516 GLGERVLGFCHLFLPDEQFPEGF-QFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGK 574
             G R +  C  F     FP G  + + D+ N  +  L  + ++ + DP R  VPDA+ K
Sbjct: 642 SEGLRTI--CLAF---RDFPAGEPEPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKK 696

Query: 575 CRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETV----EDIAARLNIPVSQVNPRDAK 630
           C+ AGI V MVTGD+  TA+AIA   GI+  G + +    +D   R+             
Sbjct: 697 CQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRIR------------ 744

Query: 631 ACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGC-------QRQGAIVAV 683
                 ++  ++  E++D I  +    V AR+SP  K  +V+G        QRQ  +VAV
Sbjct: 745 ------NEKGEIEQERIDKI--WPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQ--VVAV 794

Query: 684 TGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKK 743
           TGDG ND PALKKAD+G AMGIAG+DV+K+A+D+IL DDNF SIV  V  GR ++D++ K
Sbjct: 795 TGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISK 854

Query: 744 SIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKR 803
            + + LT N+  +             PL  V +L ++L  D + +++LA E     ++ R
Sbjct: 855 FLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLR 914

Query: 804 QP---RNPKTDKLVNERLISMAYGQIGMIQAL 832
           +P     P   + + + ++  A+ Q+ ++  L
Sbjct: 915 KPYGRNKPLISRTMMKNILGHAFYQLVVVFTL 946



 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 51/156 (32%), Positives = 85/156 (54%), Gaps = 13/156 (8%)

Query: 91  EEEPQNDNLYL---GVVLSAV-VIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEK 146
           EEE + +  ++    ++LS V V++   F+ + + K  + ++S +    Q+  VIR G+ 
Sbjct: 144 EEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVIRGGQV 202

Query: 147 MSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPL 206
           + I   ++ VGD+ +VK GD +PAD  +I  N  K+D SSLTGES+   +S D   ++PL
Sbjct: 203 IQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKSLD---KDPL 259

Query: 207 ETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATL 242
                    T+ +EG+ R +V   G  +  G I TL
Sbjct: 260 -----LLSGTHVMEGSGRMVVTAVGVNSQTGIIFTL 290


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,624,517
Number of Sequences: 37866
Number of extensions: 1542891
Number of successful extensions: 3819
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 3469
Number of HSP's gapped (non-prelim): 165
length of query: 992
length of database: 18,247,518
effective HSP length: 112
effective length of query: 880
effective length of database: 14,006,526
effective search space: 12325742880
effective search space used: 12325742880
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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