Search of human proteins with 23065544

Search of human proteins with 23065544

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23065544 glutathione S-transferase mu 1 isoform 1 [Homo
sapiens]
         (218 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23065544 glutathione S-transferase mu 1 isoform 1 [Homo sapiens]   456   e-129
gi|4504179 glutathione S-transferase mu 4 isoform 1 [Homo sapiens]    404   e-113
gi|23065563 glutathione S-transferase mu 5 [Homo sapiens]             398   e-111
gi|4504175 glutathione S-transferase mu 2 isoform 1 [Homo sapiens]    394   e-110
gi|23065547 glutathione S-transferase mu 1 isoform 2 [Homo sapiens]   362   e-100
gi|23065557 glutathione S-transferase mu 4 isoform 2 [Homo sapiens]   353   8e-98
gi|215277000 glutathione S-transferase mu 2 isoform 2 [Homo sapi...   337   4e-93
gi|23065552 glutathione S-transferase mu 3 [Homo sapiens]             337   6e-93
gi|4504183 glutathione transferase [Homo sapiens]                      96   2e-20
gi|7657457 prostaglandin-D synthase [Homo sapiens]                     73   2e-13
gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens]          59   4e-09
gi|24308514 glutathione S-transferase alpha 5 [Homo sapiens]           59   4e-09
gi|22091454 glutathione S-transferase alpha 1 [Homo sapiens]           56   3e-08
gi|24430144 glutathione S-transferase alpha 3 [Homo sapiens]           56   3e-08
gi|4504173 glutathione S-transferase alpha 4 [Homo sapiens]            45   4e-05
gi|113417526 PREDICTED: similar to glutathione S-transferase alp...    40   0.002
gi|113418092 PREDICTED: similar to glutathione S-transferase alp...    39   0.004
gi|169169045 PREDICTED: similar to glutathione S-transferase alp...    36   0.022
gi|4504187 glutathione S-transferase theta 2 [Homo sapiens]            36   0.029
gi|124249394 glutathione S-transferase theta 2B [Homo sapiens]         36   0.029
gi|11125770 aminoacyl tRNA synthetase complex-interacting multif...    33   0.25 
gi|64085252 hypothetical protein LOC145508 [Homo sapiens]              32   0.55 
gi|4758484 glutathione-S-transferase omega 1 [Homo sapiens]            31   0.93 
gi|167466164 glutathione S-transferase theta 1 [Homo sapiens]          30   1.6  
gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens]             30   1.6  
gi|13376617 prostaglandin E synthase 2 [Homo sapiens]                  28   7.9  
gi|25777744 hypothetical protein LOC267004 [Homo sapiens]              28   7.9  
gi|82880645 ubiquitin specific protease 14 isoform b [Homo sapiens]    28   7.9  
gi|4827050 ubiquitin specific protease 14 isoform a [Homo sapiens]     28   7.9  
gi|8923532 CLN6 protein [Homo sapiens]                                 28   7.9  

>gi|23065544 glutathione S-transferase mu 1 isoform 1 [Homo sapiens]
          Length = 218

 Score =  456 bits (1174), Expect = e-129
 Identities = 218/218 (100%), Positives = 218/218 (100%)

Query: 1   MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60
           MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
Sbjct: 1   MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60

Query: 61  PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120
           PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF
Sbjct: 61  PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120

Query: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180
           EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN
Sbjct: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180

Query: 181 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218
           LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK
Sbjct: 181 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218


>gi|4504179 glutathione S-transferase mu 4 isoform 1 [Homo sapiens]
          Length = 218

 Score =  404 bits (1037), Expect = e-113
 Identities = 189/218 (86%), Positives = 204/218 (93%)

Query: 1   MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60
           M M LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
Sbjct: 1   MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60

Query: 61  PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120
           PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQ MD   QL  +CY+P+F
Sbjct: 61  PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF 120

Query: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180
           EKLKP+YLEELP  ++ +S+FLGKRPWF G+KITFVDFL YDVLDLHRIFEP CLDAFPN
Sbjct: 121 EKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPN 180

Query: 181 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218
           LKDFISRFEGLEKISAYMKSSRFLP+P+++++AVWGNK
Sbjct: 181 LKDFISRFEGLEKISAYMKSSRFLPKPLYTRVAVWGNK 218


>gi|23065563 glutathione S-transferase mu 5 [Homo sapiens]
          Length = 218

 Score =  398 bits (1022), Expect = e-111
 Identities = 191/218 (87%), Positives = 202/218 (92%)

Query: 1   MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60
           MPM LGYWDIRGLAHAIRLLLEYTDSSY EKKYT+GDAPDYDRSQWLNEKFKLGLDFPNL
Sbjct: 1   MPMTLGYWDIRGLAHAIRLLLEYTDSSYVEKKYTLGDAPDYDRSQWLNEKFKLGLDFPNL 60

Query: 61  PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120
           PYLIDGAHKITQSNAIL YIARKHNLCGETEEEKIRVDILENQ MDNHM+L  +CY+P+F
Sbjct: 61  PYLIDGAHKITQSNAILRYIARKHNLCGETEEEKIRVDILENQVMDNHMELVRLCYDPDF 120

Query: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180
           EKLKPKYLEELPEKLKLYSEFLGKRPWFAG+KITFVDFL YDVLD+ RIFEPKCLDAF N
Sbjct: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGDKITFVDFLAYDVLDMKRIFEPKCLDAFLN 180

Query: 181 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218
           LKDFISRFEGL+KISAYMKSS+FL   +F K A W +K
Sbjct: 181 LKDFISRFEGLKKISAYMKSSQFLRGLLFGKSATWNSK 218


>gi|4504175 glutathione S-transferase mu 2 isoform 1 [Homo sapiens]
          Length = 218

 Score =  394 bits (1013), Expect = e-110
 Identities = 184/218 (84%), Positives = 204/218 (93%)

Query: 1   MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60
           MPM LGYW+IRGLAH+IRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
Sbjct: 1   MPMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60

Query: 61  PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120
           PYLIDG HKITQSNAIL YIARKHNLCGE+E+E+IR DILENQ MD+ MQL  +CY+P+F
Sbjct: 61  PYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDF 120

Query: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180
           EKLKP+YL+ LPE LKLYS+FLGK+PWF G+KITFVDF+ YDVL+ +++FEP CLDAFPN
Sbjct: 121 EKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPN 180

Query: 181 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218
           LKDFISRFEGLEKISAYMKSSRFLPRPVF+KMAVWGNK
Sbjct: 181 LKDFISRFEGLEKISAYMKSSRFLPRPVFTKMAVWGNK 218


>gi|23065547 glutathione S-transferase mu 1 isoform 2 [Homo sapiens]
          Length = 181

 Score =  362 bits (929), Expect = e-100
 Identities = 181/218 (83%), Positives = 181/218 (83%), Gaps = 37/218 (16%)

Query: 1   MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60
           MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
Sbjct: 1   MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60

Query: 61  PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120
           PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF
Sbjct: 61  PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120

Query: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180
           EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNK                            
Sbjct: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNK---------------------------- 152

Query: 181 LKDFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218
                    GLEKISAYMKSSRFLPRPVFSKMAVWGNK
Sbjct: 153 ---------GLEKISAYMKSSRFLPRPVFSKMAVWGNK 181


>gi|23065557 glutathione S-transferase mu 4 isoform 2 [Homo sapiens]
          Length = 195

 Score =  353 bits (905), Expect = 8e-98
 Identities = 166/189 (87%), Positives = 175/189 (92%)

Query: 1   MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60
           M M LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
Sbjct: 1   MSMTLGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60

Query: 61  PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120
           PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQ MD   QL  +CY+P+F
Sbjct: 61  PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQAMDVSNQLARVCYSPDF 120

Query: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180
           EKLKP+YLEELP  ++ +S+FLGKRPWF G+KITFVDFL YDVLDLHRIFEP CLDAFPN
Sbjct: 121 EKLKPEYLEELPTMMQHFSQFLGKRPWFVGDKITFVDFLAYDVLDLHRIFEPNCLDAFPN 180

Query: 181 LKDFISRFE 189
           LKDFISRFE
Sbjct: 181 LKDFISRFE 189


>gi|215277000 glutathione S-transferase mu 2 isoform 2 [Homo
           sapiens]
          Length = 191

 Score =  337 bits (865), Expect = 4e-93
 Identities = 156/189 (82%), Positives = 175/189 (92%)

Query: 1   MPMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60
           MPM LGYW+IRGLAH+IRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL
Sbjct: 1   MPMTLGYWNIRGLAHSIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNL 60

Query: 61  PYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEF 120
           PYLIDG HKITQSNAIL YIARKHNLCGE+E+E+IR DILENQ MD+ MQL  +CY+P+F
Sbjct: 61  PYLIDGTHKITQSNAILRYIARKHNLCGESEKEQIREDILENQFMDSRMQLAKLCYDPDF 120

Query: 121 EKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180
           EKLKP+YL+ LPE LKLYS+FLGK+PWF G+KITFVDF+ YDVL+ +++FEP CLDAFPN
Sbjct: 121 EKLKPEYLQALPEMLKLYSQFLGKQPWFLGDKITFVDFIAYDVLERNQVFEPSCLDAFPN 180

Query: 181 LKDFISRFE 189
           LKDFISRFE
Sbjct: 181 LKDFISRFE 189


>gi|23065552 glutathione S-transferase mu 3 [Homo sapiens]
          Length = 225

 Score =  337 bits (863), Expect = 6e-93
 Identities = 158/216 (73%), Positives = 185/216 (85%)

Query: 3   MILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPY 62
           M+LGYWDIRGLAHAIRLLLE+TD+SYEEK+YT G+APDYDRSQWL+ KFKL LDFPNLPY
Sbjct: 7   MVLGYWDIRGLAHAIRLLLEFTDTSYEEKRYTCGEAPDYDRSQWLDVKFKLDLDFPNLPY 66

Query: 63  LIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEK 122
           L+DG +KITQSNAIL YIARKHN+CGETEEEKIRVDI+ENQ MD   QL  +CY+ + EK
Sbjct: 67  LLDGKNKITQSNAILRYIARKHNMCGETEEEKIRVDIIENQVMDFRTQLIRLCYSSDHEK 126

Query: 123 LKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPNLK 182
           LKP+YLEELP +LK +S FLGK  WFAG K+TFVDFL YD+LD +RIF+PKCLD FPNLK
Sbjct: 127 LKPQYLEELPGQLKQFSMFLGKFSWFAGEKLTFVDFLTYDILDQNRIFDPKCLDEFPNLK 186

Query: 183 DFISRFEGLEKISAYMKSSRFLPRPVFSKMAVWGNK 218
            F+ RFE LEKI+AY++S +F   P+ +KMA WGNK
Sbjct: 187 AFMCRFEALEKIAAYLQSDQFCKMPINNKMAQWGNK 222


>gi|4504183 glutathione transferase [Homo sapiens]
          Length = 210

 Score = 96.3 bits (238), Expect = 2e-20
 Identities = 60/211 (28%), Positives = 104/211 (49%), Gaps = 13/211 (6%)

Query: 2   PMILGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLP 61
           P  + Y+ +RG   A+R+LL     S++E+  T+          W     K    +  LP
Sbjct: 3   PYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTV--------ETWQEGSLKASCLYGQLP 54

Query: 62  YLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFE 121
              DG   + QSN IL ++ R   L G+ ++E   VD++ +   D   +   + Y   +E
Sbjct: 55  KFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYT-NYE 113

Query: 122 KLKPKYLEELPEKLK----LYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDA 177
             K  Y++ LP +LK    L S+  G + +  G++I+F D+ + D+L +H +  P CLDA
Sbjct: 114 AGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDA 173

Query: 178 FPNLKDFISRFEGLEKISAYMKSSRFLPRPV 208
           FP L  ++ R     K+ A++ S  ++  P+
Sbjct: 174 FPLLSAYVGRLSARPKLKAFLASPEYVNLPI 204


>gi|7657457 prostaglandin-D synthase [Homo sapiens]
          Length = 199

 Score = 72.8 bits (177), Expect = 2e-13
 Identities = 57/203 (28%), Positives = 91/203 (44%), Gaps = 24/203 (11%)

Query: 5   LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
           L Y+++RG A  IR +  Y D  YE+ +    D P+           K  L F  +P L 
Sbjct: 6   LTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPE----------IKSTLPFGKIPILE 55

Query: 65  DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEK-- 122
                + QS AI  Y+ +  +L G TE E+  VD + + T+D+ M     C+ P  EK  
Sbjct: 56  VDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVD-TLDDFMS----CF-PWAEKKQ 109

Query: 123 -LKPKYLEEL-----PEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKCLD 176
            +K +   EL     P  ++    +LG R W  GN +T+ DF          +F+P  LD
Sbjct: 110 DVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLD 169

Query: 177 AFPNLKDFISRFEGLEKISAYMK 199
             P L     + + +  ++ ++K
Sbjct: 170 NHPRLVTLRKKVQAIPAVANWIK 192


>gi|215276987 glutathione S-transferase alpha 2 [Homo sapiens]
          Length = 222

 Score = 58.5 bits (140), Expect = 4e-09
 Identities = 56/205 (27%), Positives = 92/205 (44%), Gaps = 22/205 (10%)

Query: 5   LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
           L Y +IRG   +IR LL      +EEK   +  A D D+ +  N+ +   L F  +P + 
Sbjct: 7   LHYSNIRGRMESIRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59

Query: 65  DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD-NHMQLGMICYNPE---- 119
               K+ Q+ AIL YIA K+NL G+  +EK  +D+      D   M L +    PE    
Sbjct: 60  IDGMKLVQTRAILNYIASKYNLYGKDIKEKALIDMYIEGIADLGEMILLLPFSQPEEQDA 119

Query: 120 -----FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKC 174
                 EK K +Y     + LK + +      +  GNK++  D  + ++L      +   
Sbjct: 120 KLALIQEKTKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELDSSL 174

Query: 175 LDAFPNLKDFISRFEGLEKISAYMK 199
           + +FP LK   +R   L  +  +++
Sbjct: 175 ISSFPLLKALKTRISNLPTVKKFLQ 199


>gi|24308514 glutathione S-transferase alpha 5 [Homo sapiens]
          Length = 222

 Score = 58.5 bits (140), Expect = 4e-09
 Identities = 53/205 (25%), Positives = 93/205 (45%), Gaps = 22/205 (10%)

Query: 5   LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
           L Y + RG   +IR LL       EEK   +  A D D+ +  N+   L   F  +P + 
Sbjct: 7   LHYSNARGSMESIRWLLAAAGVELEEK--FLESAEDLDKLR--NDGSLL---FQQVPMVE 59

Query: 65  DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD-NHMQLGMICYNPE---- 119
               K+ Q+ AIL YIA K+NL G+  +E+  +D+     +D   M L ++   PE    
Sbjct: 60  IDGMKLVQTRAILNYIASKYNLYGKDMKERALIDMYTEGIVDLTEMILLLLICQPEERDA 119

Query: 120 -----FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKC 174
                 EK+K +Y     + LK +     ++ +  GNK+++ D  + ++       +   
Sbjct: 120 KTALVKEKIKNRYFPAFEKVLKSH-----RQDYLVGNKLSWADIHLVELFYYVEELDSSL 174

Query: 175 LDAFPNLKDFISRFEGLEKISAYMK 199
           + +FP LK   +R   L  +  +++
Sbjct: 175 ISSFPLLKALKTRISNLPTVKKFLQ 199


>gi|22091454 glutathione S-transferase alpha 1 [Homo sapiens]
          Length = 222

 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 53/205 (25%), Positives = 92/205 (44%), Gaps = 22/205 (10%)

Query: 5   LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
           L Y++ RG   + R LL      +EEK   +  A D D+ +  N+ +   L F  +P + 
Sbjct: 7   LHYFNARGRMESTRWLLAAAGVEFEEK--FIKSAEDLDKLR--NDGY---LMFQQVPMVE 59

Query: 65  DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD-NHMQLGMICYNPE---- 119
               K+ Q+ AIL YIA K+NL G+  +E+  +D+      D   M L +    PE    
Sbjct: 60  IDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYIEGIADLGEMILLLPVCPPEEKDA 119

Query: 120 -----FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKC 174
                 EK+K +Y     + LK + +      +  GNK++  D  + ++L      +   
Sbjct: 120 KLALIKEKIKNRYFPAFEKVLKSHGQ-----DYLVGNKLSRADIHLVELLYYVEELDSSL 174

Query: 175 LDAFPNLKDFISRFEGLEKISAYMK 199
           + +FP LK   +R   L  +  +++
Sbjct: 175 ISSFPLLKALKTRISNLPTVKKFLQ 199


>gi|24430144 glutathione S-transferase alpha 3 [Homo sapiens]
          Length = 222

 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 54/205 (26%), Positives = 90/205 (43%), Gaps = 22/205 (10%)

Query: 5   LGYWDIRGLAHAIRLLLEYTDSSYEEKKYTMGDAPDYDRSQWLNEKFKLGLDFPNLPYLI 64
           L Y++ RG    IR LL      +EEK   +G A D  + +  N+     L F  +P + 
Sbjct: 7   LHYFNGRGRMEPIRWLLAAAGVEFEEK--FIGSAEDLGKLR--NDG---SLMFQQVPMVE 59

Query: 65  DGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD-NHMQLGMICYNPE---- 119
               K+ Q+ AIL YIA K+NL G+  +E+  +D+      D N M L +    PE    
Sbjct: 60  IDGMKLVQTRAILNYIASKYNLYGKDIKERALIDMYTEGMADLNEMILLLPLCRPEEKDA 119

Query: 120 -----FEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLDLHRIFEPKC 174
                 EK K +Y     + L+ + +      +  GNK++  D  + ++L      +   
Sbjct: 120 KIALIKEKTKSRYFPAFEKVLQSHGQ-----DYLVGNKLSRADISLVELLYYVEELDSSL 174

Query: 175 LDAFPNLKDFISRFEGLEKISAYMK 199
           +  FP LK   +R   L  +  +++
Sbjct: 175 ISNFPLLKALKTRISNLPTVKKFLQ 199


>gi|4504173 glutathione S-transferase alpha 4 [Homo sapiens]
          Length = 222

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 39/173 (22%), Positives = 70/173 (40%), Gaps = 38/173 (21%)

Query: 57  FPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMD---------- 106
           F  +P +     K+ Q+ +IL YIA KHNL G+  +E+  +D+    T+D          
Sbjct: 52  FQQVPMVEIDGMKLVQTRSILHYIADKHNLFGKNLKERTLIDMYVEGTLDLLELLIMHPF 111

Query: 107 -----------NHMQLGMICYNPEFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITF 155
                      N  Q  +I Y P FEK+   +                 + +  GN+++ 
Sbjct: 112 LKPDDQQKEVVNMAQKAIIRYFPVFEKILRGH----------------GQSFLVGNQLSL 155

Query: 156 VDFLVYDVLDLHRIFEPKCLDAFPNLKDFISRFEGLEKISAYMK-SSRFLPRP 207
            D ++   +       P  L AFP L+++  +   +  I  +++  S+  P P
Sbjct: 156 ADVILLQTILALEEKIPNILSAFPFLQEYTVKLSNIPTIKRFLEPGSKKKPPP 208


>gi|113417526 PREDICTED: similar to glutathione S-transferase alpha
           3 [Homo sapiens]
          Length = 216

 Score = 40.0 bits (92), Expect = 0.002
 Identities = 45/175 (25%), Positives = 79/175 (45%), Gaps = 19/175 (10%)

Query: 57  FPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEK---------IRVDI-LENQTMD 106
           F  +P +     K+ Q+ AIL YIA K+NLCG+  +E+          RVD+ +E +   
Sbjct: 30  FQQVPMVEIDGMKLVQTRAILNYIASKYNLCGKDIKERAPYIWLFLSYRVDMYIEGRAGL 89

Query: 107 NHMQLGMICYNPEFEKLKPKYLEE--LPEKLKLYSEFL--GKRPWFAGNKITFVDFLVYD 162
           +   L    + PE +  K   ++E        ++   L   ++ +F GNK++  D  ++ 
Sbjct: 90  SEKLLHCSLHPPEEKDAKLALIKEGTTSHYFPVFETVLKSHEQDYFIGNKLSQAD--IHL 147

Query: 163 VLDLHRIFEP--KCLDAFPNLKDFISRFEGLE-KISAYMKSSRFLPRPVFSKMAV 214
           V  L+ + EP    +  FP LK  +     L+ +IS      +FL      K+ +
Sbjct: 148 VKLLYHVEEPDSSLISNFPVLKAVLCALRALKIRISKLPTVKKFLQPGSLRKLPI 202


>gi|113418092 PREDICTED: similar to glutathione S-transferase alpha
           3 [Homo sapiens]
          Length = 216

 Score = 38.5 bits (88), Expect = 0.004
 Identities = 44/175 (25%), Positives = 78/175 (44%), Gaps = 19/175 (10%)

Query: 57  FPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEK---------IRVDI-LENQTMD 106
           F  +P +     K+ Q+ AIL YI  K+NLCG+  +E+          RVD+ +E +   
Sbjct: 30  FQQVPMVEIDGMKLVQTRAILNYIVSKYNLCGKDIKERAPYIWLFLSYRVDMYIEGRAGL 89

Query: 107 NHMQLGMICYNPEFEKLKPKYLEE--LPEKLKLYSEFL--GKRPWFAGNKITFVDFLVYD 162
           +   L    + PE +  K   ++E        ++   L   ++ +F GNK++  D  ++ 
Sbjct: 90  SEKLLHCSLHPPEEKDAKLALIKEGTTSHYFPVFETVLKSHEQDYFIGNKLSQAD--IHL 147

Query: 163 VLDLHRIFEP--KCLDAFPNLKDFISRFEGLE-KISAYMKSSRFLPRPVFSKMAV 214
           V  L+ + EP    +  FP LK  +     L+ +IS      +FL      K+ +
Sbjct: 148 VKLLYHVEEPDSSLISNFPVLKAVLCALRALKIRISKLPTVKKFLQPGSLRKLPI 202


>gi|169169045 PREDICTED: similar to glutathione S-transferase alpha
           3 [Homo sapiens]
          Length = 227

 Score = 36.2 bits (82), Expect = 0.022
 Identities = 43/175 (24%), Positives = 77/175 (44%), Gaps = 19/175 (10%)

Query: 57  FPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEK---------IRVDI-LENQTMD 106
           F  +P +     K+ Q+ AIL YI  K+NLCG+  +E+          RVD+ +E +   
Sbjct: 41  FQQVPMVEIDGMKLVQTRAILNYIVSKYNLCGKDIKERAPYIWLFLSYRVDMYIEGRAGL 100

Query: 107 NHMQLGMICYNPEFEKLKPKYLEE--LPEKLKLYSEFL--GKRPWFAGNKITFVDFLVYD 162
           +   L    + PE +  K   ++E        ++   L   ++ +  GNK++  D  ++ 
Sbjct: 101 SEKLLHCSLHPPEEKDAKLALIKEGTTSHYFPVFETVLKSHEQDYLIGNKLSQAD--IHL 158

Query: 163 VLDLHRIFEP--KCLDAFPNLKDFISRFEGLE-KISAYMKSSRFLPRPVFSKMAV 214
           V  L+ + EP    +  FP LK  +     L+ +IS      +FL      K+ +
Sbjct: 159 VKLLYHVEEPDSSLISNFPVLKAVLCALRALKIRISKLPTVKKFLQPGSLRKLPI 213


>gi|4504187 glutathione S-transferase theta 2 [Homo sapiens]
          Length = 244

 Score = 35.8 bits (81), Expect = 0.029
 Identities = 34/144 (23%), Positives = 60/144 (41%), Gaps = 23/144 (15%)

Query: 40  DYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDI 99
           D  + Q  +++F        LP L DG   +T+S+AIL Y++ K+    +T +     D+
Sbjct: 34  DLVKGQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKY----QTPDHWYPSDL 89

Query: 100 LENQTMDNHMQLGMICYNPEF------EKLKPKYLEELPEKLK-------------LYSE 140
                +  ++     C    F      + L P    ++PE+               L  +
Sbjct: 90  QARARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPEEKVERNRTAMDQALQWLEDK 149

Query: 141 FLGKRPWFAGNKITFVDFLVYDVL 164
           FLG RP+ AG ++T  D +  + L
Sbjct: 150 FLGDRPFLAGQQVTLADLMALEEL 173


>gi|124249394 glutathione S-transferase theta 2B [Homo sapiens]
          Length = 244

 Score = 35.8 bits (81), Expect = 0.029
 Identities = 34/144 (23%), Positives = 60/144 (41%), Gaps = 23/144 (15%)

Query: 40  DYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDI 99
           D  + Q  +++F        LP L DG   +T+S+AIL Y++ K+    +T +     D+
Sbjct: 34  DLVKGQHKSKEFLQINSLGKLPTLKDGDFILTESSAILIYLSCKY----QTPDHWYPSDL 89

Query: 100 LENQTMDNHMQLGMICYNPEF------EKLKPKYLEELPEKLK-------------LYSE 140
                +  ++     C    F      + L P    ++PE+               L  +
Sbjct: 90  QARARVHEYLGWHADCIRGTFGIPLWVQVLGPLIGVQVPEEKVERNRTAMDQALQWLEDK 149

Query: 141 FLGKRPWFAGNKITFVDFLVYDVL 164
           FLG RP+ AG ++T  D +  + L
Sbjct: 150 FLGDRPFLAGQQVTLADLMALEEL 173


>gi|11125770 aminoacyl tRNA synthetase complex-interacting
           multifunctional protein 2 [Homo sapiens]
          Length = 320

 Score = 32.7 bits (73), Expect = 0.25
 Identities = 15/43 (34%), Positives = 24/43 (55%)

Query: 122 KLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVL 164
           +LK    +E     +  +  LGK PW AGN++T  D +++ VL
Sbjct: 243 QLKEGSSKEKAAVFRSMNSALGKSPWLAGNELTVADVVLWSVL 285


>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
          Length = 1094

 Score = 31.6 bits (70), Expect = 0.55
 Identities = 41/152 (26%), Positives = 64/152 (42%), Gaps = 11/152 (7%)

Query: 68   HKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHM---QLGMICYNPEFEKLK 124
            +K ++   +   I R+  L  E   EK R  + E Q  D  M   Q  +I      + + 
Sbjct: 908  NKESELQCLFQQIERQEQLLDEIHREK-RDLLEETQRKDEEMGSLQDRVIALETSTQ-VA 965

Query: 125  PKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDV----LDLHRIFEPKCLDAFPN 180
              +LE +PEKL L  +F   R   + ++ T   +  Y V    L  H+        +F  
Sbjct: 966  LDHLESVPEKLSLLEDFKDFRDSCSSSERTDGRYSKYRVRRNSLQHHQDDTKYRTKSFKG 1025

Query: 181  LKDFI--SRFEGLEKISAYMKSSRFLPRPVFS 210
             + F+  S   GL+  S++   SRFL  P FS
Sbjct: 1026 DRTFLEGSHTRGLDHSSSWQDHSRFLSSPRFS 1057


>gi|4758484 glutathione-S-transferase omega 1 [Homo sapiens]
          Length = 241

 Score = 30.8 bits (68), Expect = 0.93
 Identities = 23/85 (27%), Positives = 40/85 (47%), Gaps = 10/85 (11%)

Query: 119 EFEKLKPKYLEELPEKLKLYSEFLGKRPWFAGNKITFVDFLVYDVLD-LHRIFEPKCLDA 177
           EF K   K  E L  K         K  +F GN I+ +D+L++   + L  +   +C+D 
Sbjct: 145 EFRKEFTKLEEVLTNK---------KTTFFGGNSISMIDYLIWPWFERLEAMKLNECVDH 195

Query: 178 FPNLKDFISRFEGLEKISAYMKSSR 202
            P LK +++  +    +SA + S +
Sbjct: 196 TPKLKLWMAAMKEDPTVSALLTSEK 220


>gi|167466164 glutathione S-transferase theta 1 [Homo sapiens]
          Length = 240

 Score = 30.0 bits (66), Expect = 1.6
 Identities = 16/47 (34%), Positives = 25/47 (53%)

Query: 40 DYDRSQWLNEKFKLGLDFPNLPYLIDGAHKITQSNAILCYIARKHNL 86
          D  + Q L++ F        +P L DG   +T+S AIL Y+ RK+ +
Sbjct: 34 DLIKGQHLSDAFAQVNPLKKVPALKDGDFTLTESVAILLYLTRKYKV 80


>gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens]
          Length = 2156

 Score = 30.0 bits (66), Expect = 1.6
 Identities = 17/75 (22%), Positives = 32/75 (42%)

Query: 63   LIDGAHKITQSNAILCYIARKHNLCGETEEEKIRVDILENQTMDNHMQLGMICYNPEFEK 122
            LID    + + N +L   +    +CG  +   +   +  N +   +   G +   P  ++
Sbjct: 1740 LIDKGKWLLKENHLLRMSSENPGMCGNADTTSVDTLLDNNSSEVPYSHFGNLAPGPTMDE 1799

Query: 123  LKPKYLEELPEKLKL 137
            L    LEEL + L+L
Sbjct: 1800 LSSSELEELTQPLEL 1814


>gi|13376617 prostaglandin E synthase 2 [Homo sapiens]
          Length = 377

 Score = 27.7 bits (60), Expect = 7.9
 Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 6/61 (9%)

Query: 122 KLKPKYLEELPEKLKLYSEFLGK-RPWFAGNKITFVDFLVYDVLDLHRIFEPKCLDAFPN 180
           +L+    E+L E    +   +GK RP+  G K    D  VY VL   R+ E   LDAF +
Sbjct: 298 RLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVL---RVMEG--LDAFDD 352

Query: 181 L 181
           L
Sbjct: 353 L 353


>gi|25777744 hypothetical protein LOC267004 [Homo sapiens]
          Length = 593

 Score = 27.7 bits (60), Expect = 7.9
 Identities = 14/73 (19%), Positives = 33/73 (45%), Gaps = 17/73 (23%)

Query: 121 EKLKPKYLEELPEKLKLYSEFLG-----------------KRPWFAGNKITFVDFLVYDV 163
           +KLK K   + P  +K+Y++F+G                  + W++   +   + ++ + 
Sbjct: 439 QKLKKKIQVQQPNMIKVYNQFMGGVDRADENIDKYRASIRGKKWYSSPLLFCFELVLQNA 498

Query: 164 LDLHRIFEPKCLD 176
             LH+ ++ K +D
Sbjct: 499 WQLHKTYDEKPVD 511


>gi|82880645 ubiquitin specific protease 14 isoform b [Homo sapiens]
          Length = 459

 Score = 27.7 bits (60), Expect = 7.9
 Identities = 13/43 (30%), Positives = 24/43 (55%), Gaps = 3/43 (6%)

Query: 173 KCLDAFPNLKDFISRFEGLEKISAYMKSSRFLP---RPVFSKM 212
           +C+ + P LKD + R+ G  + S  M S++++    R +F  M
Sbjct: 86  QCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSM 128


>gi|4827050 ubiquitin specific protease 14 isoform a [Homo sapiens]
          Length = 494

 Score = 27.7 bits (60), Expect = 7.9
 Identities = 13/43 (30%), Positives = 24/43 (55%), Gaps = 3/43 (6%)

Query: 173 KCLDAFPNLKDFISRFEGLEKISAYMKSSRFLP---RPVFSKM 212
           +C+ + P LKD + R+ G  + S  M S++++    R +F  M
Sbjct: 121 QCIRSVPELKDALKRYAGALRASGEMASAQYITAALRDLFDSM 163


>gi|8923532 CLN6 protein [Homo sapiens]
          Length = 311

 Score = 27.7 bits (60), Expect = 7.9
 Identities = 13/32 (40%), Positives = 18/32 (56%)

Query: 117 NPEFEKLKPKYLEELPEKLKLYSEFLGKRPWF 148
           NP  + LKP+ L +  E L  Y E+LG   W+
Sbjct: 151 NPIIKNLKPETLIDSFELLYYYDEYLGHCMWY 182


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.141    0.440 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,515,623
Number of Sequences: 37866
Number of extensions: 377868
Number of successful extensions: 819
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 782
Number of HSP's gapped (non-prelim): 32
length of query: 218
length of database: 18,247,518
effective HSP length: 98
effective length of query: 120
effective length of database: 14,536,650
effective search space: 1744398000
effective search space used: 1744398000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.