Guide to the Human Genome
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Search of human proteins with 228480258

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|228480258 basic, immunoglobulin-like variable motif
containing isoform b [Homo sapiens]
         (281 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|228480258 basic, immunoglobulin-like variable motif containin...   598   e-171
gi|22095355 basic, immunoglobulin-like variable motif containing...   577   e-165
gi|27437036 colony stimulating factor 2 receptor alpha chain iso...    31   1.4  
gi|62122917 filaggrin family member 2 [Homo sapiens]                   30   1.8  
gi|20070195 colony stimulating factor 2 receptor alpha chain iso...    30   3.1  
gi|238908521 colony stimulating factor 2 receptor alpha chain is...    30   3.1  
gi|238908519 colony stimulating factor 2 receptor alpha chain is...    30   3.1  
gi|238908517 colony stimulating factor 2 receptor alpha chain is...    30   3.1  
gi|238908515 colony stimulating factor 2 receptor alpha chain is...    30   3.1  
gi|27437034 colony stimulating factor 2 receptor alpha chain iso...    30   3.1  
gi|27437032 colony stimulating factor 2 receptor alpha chain iso...    30   3.1  
gi|239752879 PREDICTED: similar to elongin C [Homo sapiens]            28   9.0  
gi|239747430 PREDICTED: similar to elongin C [Homo sapiens]            28   9.0  
gi|27437040 colony stimulating factor 2 receptor alpha chain iso...    28   9.0  

>gi|228480258 basic, immunoglobulin-like variable motif containing
           isoform b [Homo sapiens]
          Length = 281

 Score =  598 bits (1543), Expect = e-171
 Identities = 281/281 (100%), Positives = 281/281 (100%)

Query: 1   MGAGNLPPITQEEALHILGFQPPFEDIRFGPFTGNTTLMRWFRQINDHFHVKGCSYVLYK 60
           MGAGNLPPITQEEALHILGFQPPFEDIRFGPFTGNTTLMRWFRQINDHFHVKGCSYVLYK
Sbjct: 1   MGAGNLPPITQEEALHILGFQPPFEDIRFGPFTGNTTLMRWFRQINDHFHVKGCSYVLYK 60

Query: 61  PHGKNKTAGETASGALSKLTRGLKDESLAYIYHCQNHYFCPIGFEATPVKANKAFSRGPL 120
           PHGKNKTAGETASGALSKLTRGLKDESLAYIYHCQNHYFCPIGFEATPVKANKAFSRGPL
Sbjct: 61  PHGKNKTAGETASGALSKLTRGLKDESLAYIYHCQNHYFCPIGFEATPVKANKAFSRGPL 120

Query: 121 SPQEVEYWILIGESSRKHPAIHCKKWADIVTDLNTQNPEYLDIRHLERGLQYRKTKKPTF 180
           SPQEVEYWILIGESSRKHPAIHCKKWADIVTDLNTQNPEYLDIRHLERGLQYRKTKKPTF
Sbjct: 121 SPQEVEYWILIGESSRKHPAIHCKKWADIVTDLNTQNPEYLDIRHLERGLQYRKTKKPTF 180

Query: 181 FSSQVGGNLHCIIAFQRLNWQRFGLWNFPFGTIRQESQPPTHAQGIAKSESEDNISKKQH 240
           FSSQVGGNLHCIIAFQRLNWQRFGLWNFPFGTIRQESQPPTHAQGIAKSESEDNISKKQH
Sbjct: 181 FSSQVGGNLHCIIAFQRLNWQRFGLWNFPFGTIRQESQPPTHAQGIAKSESEDNISKKQH 240

Query: 241 GRLGRSFSASFHQDSAWKKMSSIHERRNSGYQGYSDYDGND 281
           GRLGRSFSASFHQDSAWKKMSSIHERRNSGYQGYSDYDGND
Sbjct: 241 GRLGRSFSASFHQDSAWKKMSSIHERRNSGYQGYSDYDGND 281


>gi|22095355 basic, immunoglobulin-like variable motif containing
           isoform a [Homo sapiens]
          Length = 503

 Score =  577 bits (1488), Expect = e-165
 Identities = 274/281 (97%), Positives = 274/281 (97%), Gaps = 7/281 (2%)

Query: 1   MGAGNLPPITQEEALHILGFQPPFEDIRFGPFTGNTTLMRWFRQINDHFHVKGCSYVLYK 60
           MGAGNLPPITQEEALHILGFQPPFEDIRFGPFTGNTTLMRWFRQINDHFHVKGCSYVLYK
Sbjct: 230 MGAGNLPPITQEEALHILGFQPPFEDIRFGPFTGNTTLMRWFRQINDHFHVKGCSYVLYK 289

Query: 61  PHGKNKTAGETASGALSKLTRGLKDESLAYIYHCQNHYFCPIGFEATPVKANKAFSRGPL 120
           PHGKNKTAGETASGALSKLTRGLKDESLAYIYHCQNHYFCPIGFEATPVKANKAFSRGPL
Sbjct: 290 PHGKNKTAGETASGALSKLTRGLKDESLAYIYHCQNHYFCPIGFEATPVKANKAFSRGPL 349

Query: 121 SPQEVEYWILIGESSRKHPAIHCKKWADIVTDLNTQNPEYLDIRHLERGLQYRKTKKPTF 180
           SPQEVEYWILIGESSRKHPAIHCKKWADIVTDLNTQNPEYLDIRHLERGLQYRKTKK   
Sbjct: 350 SPQEVEYWILIGESSRKHPAIHCKKWADIVTDLNTQNPEYLDIRHLERGLQYRKTKK--- 406

Query: 181 FSSQVGGNLHCIIAFQRLNWQRFGLWNFPFGTIRQESQPPTHAQGIAKSESEDNISKKQH 240
               VGGNLHCIIAFQRLNWQRFGLWNFPFGTIRQESQPPTHAQGIAKSESEDNISKKQH
Sbjct: 407 ----VGGNLHCIIAFQRLNWQRFGLWNFPFGTIRQESQPPTHAQGIAKSESEDNISKKQH 462

Query: 241 GRLGRSFSASFHQDSAWKKMSSIHERRNSGYQGYSDYDGND 281
           GRLGRSFSASFHQDSAWKKMSSIHERRNSGYQGYSDYDGND
Sbjct: 463 GRLGRSFSASFHQDSAWKKMSSIHERRNSGYQGYSDYDGND 503


>gi|27437036 colony stimulating factor 2 receptor alpha chain
           isoform c precursor [Homo sapiens]
          Length = 333

 Score = 30.8 bits (68), Expect = 1.4
 Identities = 42/190 (22%), Positives = 75/190 (39%), Gaps = 26/190 (13%)

Query: 112 NKAFSRGPLSPQEVEYWILIGESSRKH----------PAIHCKKWADIVTDLNTQNPEYL 161
           N  ++RGP +P++V+Y++ I  S R+              H     D ++ L ++N   +
Sbjct: 135 NCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFLV 194

Query: 162 DIRHLERGLQY----RKTKKPTFFSSQVG-----GNLHCIIAF-QRLNWQRFGLWNFPF- 210
           +    E G+Q+      TKK   F+            HC++ + Q   +Q+    +F + 
Sbjct: 195 NGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQ 254

Query: 211 -GTIRQESQPPTHAQGIAKSESEDN----ISKKQHGRLGRSFSASFHQDSAWKKMSSIHE 265
               R+ +QP T    I  S   +N     S +   +      A+  +   W   S   E
Sbjct: 255 LDVHRKNTQPGTENLLINVSGDLENRYNFPSSEPRAKHSVKIRAADVRILNWSSWSEAIE 314

Query: 266 RRNSGYQGYS 275
             + GY G S
Sbjct: 315 FGSLGYSGCS 324


>gi|62122917 filaggrin family member 2 [Homo sapiens]
          Length = 2391

 Score = 30.4 bits (67), Expect = 1.8
 Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 5/71 (7%)

Query: 211  GTIRQESQPPTHAQ-GIAKSESEDNISKKQ---HGRLGRSFS-ASFHQDSAWKKMSSIHE 265
            G+ R +SQ  TH Q G    ES   +  +    HG+ G +   A +H   + ++ SS   
Sbjct: 1436 GSHRPQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTG 1495

Query: 266  RRNSGYQGYSD 276
            RR SG+   SD
Sbjct: 1496 RRGSGHSESSD 1506


>gi|20070195 colony stimulating factor 2 receptor alpha chain
           isoform a precursor [Homo sapiens]
          Length = 400

 Score = 29.6 bits (65), Expect = 3.1
 Identities = 30/132 (22%), Positives = 57/132 (43%), Gaps = 22/132 (16%)

Query: 112 NKAFSRGPLSPQEVEYWILIGESSRKH----------PAIHCKKWADIVTDLNTQNPEYL 161
           N  ++RGP +P++V+Y++ I  S R+              H     D ++ L ++N   +
Sbjct: 135 NCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFLV 194

Query: 162 DIRHLERGLQY----RKTKKPTFFSSQVG-----GNLHCIIAF-QRLNWQRFGLWNFPF- 210
           +    E G+Q+      TKK   F+            HC++ + Q   +Q+    +F + 
Sbjct: 195 NGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQ 254

Query: 211 -GTIRQESQPPT 221
               R+ +QP T
Sbjct: 255 LDVHRKNTQPGT 266


>gi|238908521 colony stimulating factor 2 receptor alpha chain
           isoform h [Homo sapiens]
          Length = 267

 Score = 29.6 bits (65), Expect = 3.1
 Identities = 30/132 (22%), Positives = 57/132 (43%), Gaps = 22/132 (16%)

Query: 112 NKAFSRGPLSPQEVEYWILIGESSRKH----------PAIHCKKWADIVTDLNTQNPEYL 161
           N  ++RGP +P++V+Y++ I  S R+              H     D ++ L ++N   +
Sbjct: 2   NCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFLV 61

Query: 162 DIRHLERGLQY----RKTKKPTFFSSQVG-----GNLHCIIAF-QRLNWQRFGLWNFPF- 210
           +    E G+Q+      TKK   F+            HC++ + Q   +Q+    +F + 
Sbjct: 62  NGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQ 121

Query: 211 -GTIRQESQPPT 221
               R+ +QP T
Sbjct: 122 LDVHRKNTQPGT 133


>gi|238908519 colony stimulating factor 2 receptor alpha chain
           isoform g precursor [Homo sapiens]
          Length = 410

 Score = 29.6 bits (65), Expect = 3.1
 Identities = 30/132 (22%), Positives = 57/132 (43%), Gaps = 22/132 (16%)

Query: 112 NKAFSRGPLSPQEVEYWILIGESSRKH----------PAIHCKKWADIVTDLNTQNPEYL 161
           N  ++RGP +P++V+Y++ I  S R+              H     D ++ L ++N   +
Sbjct: 135 NCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFLV 194

Query: 162 DIRHLERGLQY----RKTKKPTFFSSQVG-----GNLHCIIAF-QRLNWQRFGLWNFPF- 210
           +    E G+Q+      TKK   F+            HC++ + Q   +Q+    +F + 
Sbjct: 195 NGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQ 254

Query: 211 -GTIRQESQPPT 221
               R+ +QP T
Sbjct: 255 LDVHRKNTQPGT 266


>gi|238908517 colony stimulating factor 2 receptor alpha chain
           isoform f precursor [Homo sapiens]
          Length = 434

 Score = 29.6 bits (65), Expect = 3.1
 Identities = 30/132 (22%), Positives = 57/132 (43%), Gaps = 22/132 (16%)

Query: 112 NKAFSRGPLSPQEVEYWILIGESSRKH----------PAIHCKKWADIVTDLNTQNPEYL 161
           N  ++RGP +P++V+Y++ I  S R+              H     D ++ L ++N   +
Sbjct: 135 NCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFLV 194

Query: 162 DIRHLERGLQY----RKTKKPTFFSSQVG-----GNLHCIIAF-QRLNWQRFGLWNFPF- 210
           +    E G+Q+      TKK   F+            HC++ + Q   +Q+    +F + 
Sbjct: 195 NGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQ 254

Query: 211 -GTIRQESQPPT 221
               R+ +QP T
Sbjct: 255 LDVHRKNTQPGT 266


>gi|238908515 colony stimulating factor 2 receptor alpha chain
           isoform a precursor [Homo sapiens]
          Length = 400

 Score = 29.6 bits (65), Expect = 3.1
 Identities = 30/132 (22%), Positives = 57/132 (43%), Gaps = 22/132 (16%)

Query: 112 NKAFSRGPLSPQEVEYWILIGESSRKH----------PAIHCKKWADIVTDLNTQNPEYL 161
           N  ++RGP +P++V+Y++ I  S R+              H     D ++ L ++N   +
Sbjct: 135 NCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFLV 194

Query: 162 DIRHLERGLQY----RKTKKPTFFSSQVG-----GNLHCIIAF-QRLNWQRFGLWNFPF- 210
           +    E G+Q+      TKK   F+            HC++ + Q   +Q+    +F + 
Sbjct: 195 NGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQ 254

Query: 211 -GTIRQESQPPT 221
               R+ +QP T
Sbjct: 255 LDVHRKNTQPGT 266


>gi|27437034 colony stimulating factor 2 receptor alpha chain
           isoform b precursor [Homo sapiens]
          Length = 377

 Score = 29.6 bits (65), Expect = 3.1
 Identities = 30/132 (22%), Positives = 57/132 (43%), Gaps = 22/132 (16%)

Query: 112 NKAFSRGPLSPQEVEYWILIGESSRKH----------PAIHCKKWADIVTDLNTQNPEYL 161
           N  ++RGP +P++V+Y++ I  S R+              H     D ++ L ++N   +
Sbjct: 135 NCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFLV 194

Query: 162 DIRHLERGLQY----RKTKKPTFFSSQVG-----GNLHCIIAF-QRLNWQRFGLWNFPF- 210
           +    E G+Q+      TKK   F+            HC++ + Q   +Q+    +F + 
Sbjct: 195 NGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQ 254

Query: 211 -GTIRQESQPPT 221
               R+ +QP T
Sbjct: 255 LDVHRKNTQPGT 266


>gi|27437032 colony stimulating factor 2 receptor alpha chain
           isoform a precursor [Homo sapiens]
          Length = 400

 Score = 29.6 bits (65), Expect = 3.1
 Identities = 30/132 (22%), Positives = 57/132 (43%), Gaps = 22/132 (16%)

Query: 112 NKAFSRGPLSPQEVEYWILIGESSRKH----------PAIHCKKWADIVTDLNTQNPEYL 161
           N  ++RGP +P++V+Y++ I  S R+              H     D ++ L ++N   +
Sbjct: 135 NCTWARGPTAPRDVQYFLYIRNSKRRREIRCPYYIQDSGTHVGCHLDNLSGLTSRNYFLV 194

Query: 162 DIRHLERGLQY----RKTKKPTFFSSQVG-----GNLHCIIAF-QRLNWQRFGLWNFPF- 210
           +    E G+Q+      TKK   F+            HC++ + Q   +Q+    +F + 
Sbjct: 195 NGTSREIGIQFFDSLLDTKKIERFNPPSNVTVRCNTTHCLVRWKQPRTYQKLSYLDFQYQ 254

Query: 211 -GTIRQESQPPT 221
               R+ +QP T
Sbjct: 255 LDVHRKNTQPGT 266


>gi|239752879 PREDICTED: similar to elongin C [Homo sapiens]
          Length = 269

 Score = 28.1 bits (61), Expect = 9.0
 Identities = 12/26 (46%), Positives = 15/26 (57%)

Query: 42  FRQINDHFHVKGCSYVLYKPHGKNKT 67
           FR+I+ H   K C YV YK H  N +
Sbjct: 219 FREISSHVLSKVCMYVTYKGHYTNSS 244


>gi|239747430 PREDICTED: similar to elongin C [Homo sapiens]
          Length = 269

 Score = 28.1 bits (61), Expect = 9.0
 Identities = 12/26 (46%), Positives = 15/26 (57%)

Query: 42  FRQINDHFHVKGCSYVLYKPHGKNKT 67
           FR+I+ H   K C YV YK H  N +
Sbjct: 219 FREISSHVLSKVCMYVTYKGHYTNSS 244


>gi|27437040 colony stimulating factor 2 receptor alpha chain
           isoform e precursor [Homo sapiens]
          Length = 233

 Score = 28.1 bits (61), Expect = 9.0
 Identities = 10/26 (38%), Positives = 19/26 (73%)

Query: 112 NKAFSRGPLSPQEVEYWILIGESSRK 137
           N  ++RGP +P++V+Y++ I  S R+
Sbjct: 135 NCTWARGPTAPRDVQYFLYIRNSKRR 160


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,115,366
Number of Sequences: 37866
Number of extensions: 539277
Number of successful extensions: 1107
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 1091
Number of HSP's gapped (non-prelim): 18
length of query: 281
length of database: 18,247,518
effective HSP length: 101
effective length of query: 180
effective length of database: 14,423,052
effective search space: 2596149360
effective search space used: 2596149360
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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