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Search of human proteins with 22749425
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22749425 spermatid associated [Homo sapiens]
(448 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22749425 spermatid associated [Homo sapiens] 903 0.0
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 50 3e-06
gi|95089461 discs large homolog 5 [Homo sapiens] 50 3e-06
gi|66773344 hypothetical protein LOC140710 [Homo sapiens] 50 5e-06
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 49 7e-06
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 49 9e-06
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 49 1e-05
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 48 2e-05
gi|221219020 NYD-SP11 protein [Homo sapiens] 47 3e-05
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 47 5e-05
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 45 1e-04
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 45 1e-04
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 45 1e-04
gi|50980301 myosin phosphatase-Rho interacting protein isoform 2... 45 1e-04
gi|50980307 myosin phosphatase-Rho interacting protein isoform 1... 45 1e-04
gi|51944974 tumor suppressor candidate 1 [Homo sapiens] 45 1e-04
gi|156766068 CDC42 binding protein kinase gamma (DMPK-like) [Hom... 45 2e-04
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 45 2e-04
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 44 2e-04
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 44 2e-04
gi|38176300 nestin [Homo sapiens] 44 3e-04
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 44 4e-04
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 44 4e-04
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 44 4e-04
gi|169168460 PREDICTED: chibby homolog 3 (Drosophila) [Homo sapi... 43 5e-04
gi|88990086 PREDICTED: chibby homolog 3 (Drosophila) [Homo sapiens] 43 5e-04
gi|88986509 PREDICTED: chibby homolog 3 (Drosophila) [Homo sapiens] 43 5e-04
gi|221139761 zinc finger protein 853 [Homo sapiens] 42 9e-04
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 42 9e-04
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 42 9e-04
>gi|22749425 spermatid associated [Homo sapiens]
Length = 448
Score = 903 bits (2333), Expect = 0.0
Identities = 448/448 (100%), Positives = 448/448 (100%)
Query: 1 MSPLECSECFGDQLLHRTYTWQLTLHSRPNYTRKRDTRSESLEIPISVVLPQRGTAEPFP 60
MSPLECSECFGDQLLHRTYTWQLTLHSRPNYTRKRDTRSESLEIPISVVLPQRGTAEPFP
Sbjct: 1 MSPLECSECFGDQLLHRTYTWQLTLHSRPNYTRKRDTRSESLEIPISVVLPQRGTAEPFP 60
Query: 61 RLHNLYSTPRCAQQAALPRLSRRMASQHSYPLNRFSSVPLDPMERPMSQADLELDYNPPR 120
RLHNLYSTPRCAQQAALPRLSRRMASQHSYPLNRFSSVPLDPMERPMSQADLELDYNPPR
Sbjct: 61 RLHNLYSTPRCAQQAALPRLSRRMASQHSYPLNRFSSVPLDPMERPMSQADLELDYNPPR 120
Query: 121 VQLSDEMFVFQDGRWVNENCRLQSPYFSPSASFHHKLHHKRLAKECMLQEENKSLREENK 180
VQLSDEMFVFQDGRWVNENCRLQSPYFSPSASFHHKLHHKRLAKECMLQEENKSLREENK
Sbjct: 121 VQLSDEMFVFQDGRWVNENCRLQSPYFSPSASFHHKLHHKRLAKECMLQEENKSLREENK 180
Query: 181 ALREENRMLSKENKILQVFWEEHKASLGREESRAPSPLLHKDSASLEVVKKDHVALQVPR 240
ALREENRMLSKENKILQVFWEEHKASLGREESRAPSPLLHKDSASLEVVKKDHVALQVPR
Sbjct: 181 ALREENRMLSKENKILQVFWEEHKASLGREESRAPSPLLHKDSASLEVVKKDHVALQVPR 240
Query: 241 GKEDSTLQLLREENRALQQLLEQKQAYWAQAEDTAAPAEESKPAPSPHEEPCSPGLLQDQ 300
GKEDSTLQLLREENRALQQLLEQKQAYWAQAEDTAAPAEESKPAPSPHEEPCSPGLLQDQ
Sbjct: 241 GKEDSTLQLLREENRALQQLLEQKQAYWAQAEDTAAPAEESKPAPSPHEEPCSPGLLQDQ 300
Query: 301 GSGLSSRFEEPKGPPARQEDSKELRALRKMVSNMSGPSGEEEAKVGPGLPDGCQPLQLLR 360
GSGLSSRFEEPKGPPARQEDSKELRALRKMVSNMSGPSGEEEAKVGPGLPDGCQPLQLLR
Sbjct: 301 GSGLSSRFEEPKGPPARQEDSKELRALRKMVSNMSGPSGEEEAKVGPGLPDGCQPLQLLR 360
Query: 361 EMRQALQALLKENRLLQEENRTLQVLRAEHRGFQEENKALWENNKLKLQQKLVIDTVTEV 420
EMRQALQALLKENRLLQEENRTLQVLRAEHRGFQEENKALWENNKLKLQQKLVIDTVTEV
Sbjct: 361 EMRQALQALLKENRLLQEENRTLQVLRAEHRGFQEENKALWENNKLKLQQKLVIDTVTEV 420
Query: 421 TARMEMLIEELYAFMPARSQDPKKPSRV 448
TARMEMLIEELYAFMPARSQDPKKPSRV
Sbjct: 421 TARMEMLIEELYAFMPARSQDPKKPSRV 448
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 50.4 bits (119), Expect = 3e-06
Identities = 58/303 (19%), Positives = 120/303 (39%), Gaps = 31/303 (10%)
Query: 148 SPSASFHHKLHHKRLAKECMLQEENKSLREENKALREENRMLSKENKIL----------Q 197
S SA ++ L Q+E K R+E K E ++ +E KI +
Sbjct: 264 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEE 323
Query: 198 VFWEEHKASLGREESRAPSPLLHKDSASLEVVKKDHVALQVPRGKEDSTLQLLREENRAL 257
+ WE+ + +EE + K+ E+ +K H ++ +E + E+ R
Sbjct: 324 MMWEKEEKMRRQEEM-----MWEKEEKIRELEEKMHEQEKI---REQEEKRQEEEKIREQ 375
Query: 258 QQLLEQKQAYWAQAEDTAAPAEESKPAPS-PHEEPCSPGLLQDQGSGLSSRFEEPKGPPA 316
++ EQ+ W Q E E+ + E+ G +++ +E +
Sbjct: 376 EKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMR 435
Query: 317 RQED-----SKELRALRKMVSNMSGPSGEEEAKVGPGLPDGCQPLQLLRE----MRQALQ 367
RQE+ K++R + + E+E K+G C+ ++E MR+ +
Sbjct: 436 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEE 495
Query: 368 ALLKENRLLQEENRTLQVLRAEHRGFQEENKALWENNKLKLQQKLVIDTVTEVTARMEML 427
+ ++ + ++E+ + +R + QE+ + +WE + +Q+ + E R E
Sbjct: 496 KIREQEKKIREQE---EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 552
Query: 428 IEE 430
+ E
Sbjct: 553 MRE 555
>gi|95089461 discs large homolog 5 [Homo sapiens]
Length = 1919
Score = 50.4 bits (119), Expect = 3e-06
Identities = 49/183 (26%), Positives = 79/183 (43%), Gaps = 23/183 (12%)
Query: 112 LELDYNPPRVQLSDEMFVFQDGRWVNENCRLQSPYFSPSASFHHKLHHKRLAKECMLQEE 171
L DY ++Q M Q + + N + + F+H LH + L+ + L+++
Sbjct: 184 LNPDYERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRLKDD 243
Query: 172 NKSLREENKALREENRMLSKENKILQVFWEEHKASLGREESRAPSPLLHKDSA------- 224
LR EN L E +L + + ++ EE + +G ++ L H S+
Sbjct: 244 VDMLRRENGQLLRERNLLQQSWEDMKRLHEEDQKEIGDLRAQQQQVLKHNGSSEILNKLY 303
Query: 225 -----SLEVVKKDHVALQ-------VPRGKEDSTLQLLREENRALQQLLEQKQAYWAQAE 272
LEVVKKD+ AL+ + S L+ L EEN Q+LL+Q + Q
Sbjct: 304 DTAMDKLEVVKKDYDALRKRYSEKVAIHNADLSRLEQLGEEN---QRLLKQTEML-TQQR 359
Query: 273 DTA 275
DTA
Sbjct: 360 DTA 362
>gi|66773344 hypothetical protein LOC140710 [Homo sapiens]
Length = 1016
Score = 49.7 bits (117), Expect = 5e-06
Identities = 71/269 (26%), Positives = 122/269 (45%), Gaps = 44/269 (16%)
Query: 161 RLAKECMLQEENKS-LREENKALREENRMLSKENKILQVFWE---EHKA------SLGRE 210
RL KE + E+ ++ L EEN+ LR+ ++LQ E EH SLG+
Sbjct: 74 RLHKELEVVEKKRARLEEENEELRQRLIETELAKQVLQTELERPREHSLKKRGTRSLGKA 133
Query: 211 ESRAPSPLLHKDSASLEVVKKDHVALQVPRGKEDSTL------QLLREENRALQQLLEQK 264
+ + L+ +DSA L+ Q+ KE+S L +L +E + ++LL+ +
Sbjct: 134 DKKT---LVQEDSADLKC--------QLHFAKEESALMCKKLTKLAKENDSMKEELLKYR 182
Query: 265 QAYWAQAEDTAAPAEESKPAPSPHEEPCSPGL--LQDQGSGLSSRFEEPKGPPARQEDSK 322
Y D+A AEE AP E L ++++ + LS R E + +++
Sbjct: 183 SLYGDL--DSALSAEELADAPHSRETELKVHLKLVEEEANLLSRRIVE------LEVENR 234
Query: 323 ELRALRKMVSNMSGPSGEEEAKVGPGLPDGCQPLQLLREMRQALQALLKENRL------- 375
LRA + + G G EA++ G + + L E+R+ LQ + +E L
Sbjct: 235 GLRAEMDDMKDHGGGCGGPEARLAFSALGGGECGESLAELRRHLQFVEEEAELLRRSSAE 294
Query: 376 LQEENRTLQVLRAEHRGFQEENKALWENN 404
L+++N+ L A+ R E + AL E++
Sbjct: 295 LEDQNKLLLNELAKFRSEHELDVALSEDS 323
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 49.3 bits (116), Expect = 7e-06
Identities = 51/269 (18%), Positives = 112/269 (41%), Gaps = 40/269 (14%)
Query: 164 KECMLQEENKSLREENKALREENRMLSKENKILQV---FWEEHKASLGREESRAPSPLLH 220
KE M ++E K ++E K R+E ++ +E KI + W + + +EE +H
Sbjct: 495 KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMH 554
Query: 221 KDSASLEVVKKDHVALQVPRGKEDSTLQLLREENRALQQLLEQKQAYWAQAEDTAAPAEE 280
+ E K+ +ED ++ R+E +++ EQ++ W Q E E+
Sbjct: 555 EQEKIWEEEKRQE--------QED---KMWRQE----EKIREQEEKVWRQEEKIREQEEK 599
Query: 281 SKPAPSPHEEPCSPGLLQDQGSGLSSRFEEPKGPPAR-QEDSKELRALRKMVSNMSGPSG 339
Q+Q + + E+ + + QE +++R + + +
Sbjct: 600 R----------------QEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQ 643
Query: 340 EEEAKVGPGLPDGCQPLQLLREMRQALQALLKENRLLQEENRTLQV---LRAEHRGFQEE 396
E+E K+G C+ + ++E + + +E ++ ++E + + +R + QE+
Sbjct: 644 EQEEKMGEQEEKMCEQEEKMQEQEETMWR--QEEKIREQEKKIREQEEKIREQEEMMQEQ 701
Query: 397 NKALWENNKLKLQQKLVIDTVTEVTARME 425
+ +WE + +Q+ + E R E
Sbjct: 702 EEKMWEQEEKMCEQEEKMQEQEEKMRRQE 730
Score = 36.2 bits (82), Expect = 0.062
Identities = 53/310 (17%), Positives = 126/310 (40%), Gaps = 28/310 (9%)
Query: 131 QDGRWVNENCRLQSPYFSPSASFHHKLHHKRLAKECMLQEENKSLREENKALREENRMLS 190
++ R E R Q A + R +E + ++E K R+E K + E+ ++
Sbjct: 410 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEK-IHEQEKIRE 468
Query: 191 KENKILQVFWEEHKASLGREESRAPSPLLHKDSASLEVVKKDHVALQVPRGKEDSTLQLL 250
+E + + + + R+E + +H+ +K H + R +E+ +
Sbjct: 469 EEKR-------QEQEEMWRQEEK-----IHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQE 516
Query: 251 REENRALQQLLEQKQAYWAQAEDTAAPAEESKPAPSPHEEP--CSPGLLQDQGSGLSSRF 308
+ +++ EQ++ W Q E E + HE+ Q+Q + +
Sbjct: 517 EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576
Query: 309 EEPKGPPARQEDSKELRALRKMVSNMSGPSGEEEA--KVGPGLPDGCQPLQLLRE-MRQA 365
E+ R+++ K R K+ +EE K + + + +Q E +R+
Sbjct: 577 EK-----IREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQ 631
Query: 366 LQALLKENRLLQEENRTL----QVLRAEHRGFQEENKALW-ENNKLKLQQKLVIDTVTEV 420
+ + ++ + QE+ + + + + QE+ + +W + K++ Q+K + + ++
Sbjct: 632 EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKI 691
Query: 421 TARMEMLIEE 430
+ EM+ E+
Sbjct: 692 REQEEMMQEQ 701
Score = 35.4 bits (80), Expect = 0.11
Identities = 46/257 (17%), Positives = 105/257 (40%), Gaps = 29/257 (11%)
Query: 164 KECMLQEENKSLREENKALREENRMLSKENKILQVFWEEHKASLGREESRAPSPLLHKDS 223
+E M ++E +E K R+E M KE KI ++ + H+ RE+
Sbjct: 362 EEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ------------ 409
Query: 224 ASLEVVKKDHVALQVPRGKEDSTLQLLREENRALQQ---LLEQKQAYWAQAEDTAAPAEE 280
E +++ ++ +++ ++ R+E + +Q + EQ++ W Q E +
Sbjct: 410 ---EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKI 466
Query: 281 SKPAPSPHEEPCSPGLLQDQGSGLSSRFEEPKGPPARQEDSKELRALRKMVSNMSGPSGE 340
+ +E + Q + + E + E +++R + V E
Sbjct: 467 REEEKRQEQEE-----MWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIRE 521
Query: 341 EEAKVGPGLPDGCQPLQLLR---EMRQALQALLKENRLLQEENRTLQ---VLRAEHRGFQ 394
+E K+ + + +R EM + + + ++ ++ +EE R Q + R E + +
Sbjct: 522 QEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIRE 581
Query: 395 EENKALWENNKLKLQQK 411
+E K + K++ Q++
Sbjct: 582 QEEKVWRQEEKIREQEE 598
Score = 32.7 bits (73), Expect = 0.68
Identities = 39/236 (16%), Positives = 99/236 (41%), Gaps = 37/236 (15%)
Query: 160 KRLAKECMLQEENKSLREENKALREENRMLSKENKILQVFWEEHKASLGREESRAPSPLL 219
+++ ++ + EE K +E+K R+E ++ +E K+ W + + +EE R
Sbjct: 551 EKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKV----WRQEEKIREQEEKRQEQE-- 604
Query: 220 HKDSASLEVVKKDHVALQVPRGKEDSTLQLLREENRALQQLLEQKQAYWAQAEDTAAPAE 279
K E +++ +Q +++ ++ E+ R +++ ++++ + E+ E
Sbjct: 605 EKMWKQEEKIREQEEKIQ----EQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE 660
Query: 280 ESKPAPSPHEEPCSPGLLQDQGSGLSSRFEEPKGPPARQEDSKELRALRKMVSNMSGPSG 339
E +Q+Q + + E+ + E K++R + +
Sbjct: 661 EK---------------MQEQEETMWRQEEKIR------EQEKKIREQEEKIREQEEMMQ 699
Query: 340 EEEAKVGPGLPDGCQPLQLLREMRQALQALLKENRLLQEENRTLQVLRAEHRGFQE 395
E+E K+ C+ + ++E + ++ +E ++ ++E R LR + QE
Sbjct: 700 EQEEKMWEQEEKMCEQEEKMQEQEEKMRR--QEEKMWEQEVR----LRQQEEKMQE 749
Score = 29.6 bits (65), Expect = 5.8
Identities = 42/280 (15%), Positives = 109/280 (38%), Gaps = 22/280 (7%)
Query: 148 SPSASFHHKLHHKRLAKECMLQEENKSLREENKALREENRMLSKENKILQVFWEEHKASL 207
S SA ++ L Q+E K R+E K E ++ +E KI + +E K
Sbjct: 276 SVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIRE---QEEKIRE 332
Query: 208 GREESRAPSPLLHKDSASLEVVKKDHVALQVPRGKEDSTLQLLREENRALQQLLEQKQAY 267
E+ R ++ + + ++ + +++ + E+ R ++++ +K+
Sbjct: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 392
Query: 268 WAQAEDTAAPAEESKPAPSPHEEPCSPGLLQDQGSGLSSRFEEPKGPPARQEDSKELRAL 327
+ E+ E+ + +E ++ + +E + RQE+ ++R
Sbjct: 393 IRELEEKMHEQEKIREQEEKRQE--------EEKIREQEKRQEQEAKMWRQEE--KIREQ 442
Query: 328 RKMVSNMSGPSGEEEAKVGPGLPDGCQPLQLLREMRQALQALLKENRLLQEENRTLQVLR 387
+ + +E K+ Q E RQ + + ++ + E+ ++ R
Sbjct: 443 EEKIREQEKKMWRQEEKIHE------QEKIREEEKRQEQEEMWRQEEKIHEQE---EIWR 493
Query: 388 AEHRGFQEENKALWENNKLKLQQKLVIDTVTEVTARMEML 427
+ + ++E K + K+ Q++ + + ++ + E +
Sbjct: 494 QKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKM 533
Score = 28.9 bits (63), Expect = 9.9
Identities = 25/125 (20%), Positives = 50/125 (40%), Gaps = 15/125 (12%)
Query: 156 KLHHKRLAKECMLQEENKSLREENKALREENRMLSKENKILQVFWEEHKASLGREESRAP 215
K K +E +QE+ + +RE+ + +RE+ M +E + +G +E +
Sbjct: 609 KQEEKIREQEEKIQEQEEKIREQEEKIREQEEMT-----------QEQEEKMGEQEEKM- 656
Query: 216 SPLLHKDSASLEVVKKDHVALQVPRGKEDSTLQLLREENRALQQLLEQKQAYWAQAEDTA 275
K E + + ++ K + +RE+ +Q EQ++ W Q E
Sbjct: 657 CEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQ---EQEEKMWEQEEKMC 713
Query: 276 APAEE 280
E+
Sbjct: 714 EQEEK 718
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 48.9 bits (115), Expect = 9e-06
Identities = 70/284 (24%), Positives = 121/284 (42%), Gaps = 36/284 (12%)
Query: 156 KLHHKRLAKECMLQEENKSLREENKALREENRMLSKENKILQ-------VFWEEHKASLG 208
K+ KRL + L++ENKSL +E L ++ + L KENK L+ EE+ +G
Sbjct: 804 KISSKRLEQ---LEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIG 860
Query: 209 REESRAPSPL----LHKDSA-SLEVVKKDHVALQVPRGKEDSTLQLLREE---------- 253
E + ++K+S L+ ++K++ L + TL LRE+
Sbjct: 861 NLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQ 920
Query: 254 -NRALQQLLEQKQAYWAQAE----DTAAPAEESKPAPSPHEEPCSPGL--LQDQGSGLSS 306
N L++L + + E D + + K S E L +++ + L +
Sbjct: 921 MNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEA 980
Query: 307 RFEEPKGPPARQEDSKELRALRKMVSNMSGPSGEEEAKVGPGLPDGCQPLQLLREMRQAL 366
R EE Q+ +EL+ ++K + +EE V P + + RE ++
Sbjct: 981 RLEESTN--YNQQLRQELKTVKKNYEALKQRQ-DEERMVQSSPPISGEDNKWERESQETT 1037
Query: 367 QALLKENRLLQEENRTLQVLRAEHRGFQEENKAL-WENNKLKLQ 409
+ LLK L E R L+AE + + + K L +NN L+ Q
Sbjct: 1038 RELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQ 1081
Score = 40.8 bits (94), Expect = 0.003
Identities = 67/301 (22%), Positives = 121/301 (40%), Gaps = 68/301 (22%)
Query: 148 SPSASFHHKLHHKRLAKECMLQEENKSLREENKALR-----------------EENRMLS 190
+P S H+++ ++ L+ EN+SL + + LR +EN+ LS
Sbjct: 445 APQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLS 504
Query: 191 KENKILQVFWEEHKASLGREESRAPSPLLHKDSASLEVVKKDHVALQVPRGKEDSTLQLL 250
K+ +IL+ + K SL + + S L K+ A LE ++ R + +++L
Sbjct: 505 KKVEILENEIVQEKQSL--QNCQNLSKDLMKEKAQLEKT------IETLRENSERQIKIL 556
Query: 251 REENRALQQLLEQKQAYWAQAEDTAAPAEESKPAPSPHEEPCSPGLLQDQGSGLSS-RFE 309
+EN L Q + + +Q A + K HE +++ S LS FE
Sbjct: 557 EQENEHLNQTVSSLRQR-SQISAEARVKDIEKENKILHES------IKETSSKLSKIEFE 609
Query: 310 EPKGPPARQEDSKELRALRKMVSNMSGPSGEEEAKVGPGLPDGCQPLQLLREMRQALQAL 369
+++ KEL ++ GE E+ L L
Sbjct: 610 -------KRQIKKELEHYKE--------KGERA-----------------EELENELHHL 637
Query: 370 LKENRLLQEENRTLQVLRAEHRGFQEENKALWENNKLKLQQKLVIDTVTEVTARMEMLIE 429
KEN LLQ++ L++ + ++EN L N+ + K +D+ +T ++E L +
Sbjct: 638 EKENELLQKKITNLKITCEKIEALEQENSELERENR---KLKKTLDSFKNLTFQLESLEK 694
Query: 430 E 430
E
Sbjct: 695 E 695
Score = 32.7 bits (73), Expect = 0.68
Identities = 64/292 (21%), Positives = 119/292 (40%), Gaps = 32/292 (10%)
Query: 138 ENCRLQ---SPYFSPSASFHHKLHHKRLAKECMLQEENKSLREENKALREENRMLSKENK 194
+N +LQ S S S S ++ + + L ++ L+ EN+S+ +E + L+ L K+++
Sbjct: 1102 QNAKLQVENSTLNSQSTSLMNQ-NAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHE 1160
Query: 195 ILQVFWEEHKASLGREESRAPSPLLHKDSASLEVVKKD----HVALQVPRGKEDSTLQLL 250
L++ E + E + L +LEV +D + L +G+ + ++L
Sbjct: 1161 KLELLHERQASEY--ESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKML 1218
Query: 251 REENRALQQLLEQKQAYWAQAEDTAAPAEESKPAPSPHEEPCSPGLLQDQGSGLSSRFEE 310
+ E + LLE K AE E + + + +LQ L S
Sbjct: 1219 KVEQEKM--LLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNN 1276
Query: 311 PKGPPARQEDSKELRALRKMVSNMSGPSGEEEAKVGPGLPDGCQPLQLL--------REM 362
K R E E L++ + S + L + C+ L L R +
Sbjct: 1277 SKLEQTRLE--AEFSKLKEQYQQLDITSTK--------LNNQCELLSQLKGNLEEENRHL 1326
Query: 363 RQALQALLKENRLLQEEN-RTLQVLRAEHRGFQEENKALWENNKLKLQQKLV 413
+Q L+ +NR L E+N + + E R + ++ L K KL++K++
Sbjct: 1327 LDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNEL-RRQKEKLEEKIM 1377
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 48.5 bits (114), Expect = 1e-05
Identities = 73/275 (26%), Positives = 119/275 (43%), Gaps = 59/275 (21%)
Query: 167 MLQEENKSLREENKALREENRMLSKENKILQVFWEEHKASLGREESRAPSPLLHKDSASL 226
+L E KSL EEN L E + LS++ L+VF + +
Sbjct: 682 VLSAEVKSLYEENNKLSSEKKQLSRD---LEVFLSQKE---------------------- 716
Query: 227 EVVKKDHVA-----LQVPRGKEDSTLQLLREENRALQQLLEQKQAYWAQAEDTAAPAEES 281
+V+ K+H+ LQ+ ++D+ +LL EN +Q+L + Q Y E + +E+S
Sbjct: 717 DVILKEHITQLEKKLQLMVEEQDNLNKLL--ENEQVQKLFVKTQLYGFLKEMGSEVSEDS 774
Query: 282 KPAPSPHEEPCSPGLLQDQGSGLSSRFEEPKGPPARQEDSKELRALRKMVSNMSGPSGEE 341
EE +LQ G L ++ E K A Q D K L L K + + +E
Sbjct: 775 -------EEKDVVNVLQAVGESL-AKINEEKCNLAFQRDEKVLE-LEKEIKCL-----QE 820
Query: 342 EAKVGPGLPDGCQPLQ-LLREMRQALQALLKENRLLQEENRTLQVLRAEHRGFQEENKAL 400
E+ V C+ L+ LLR+ Q L KE +Q E LQ E + E+ +
Sbjct: 821 ESVV------QCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQSDLLEMKNANEKTRL- 873
Query: 401 WENNKLKLQQKLVIDTVTEVTARMEMLIEELYAFM 435
EN L +Q ++ V++ ++ E+ E+ F+
Sbjct: 874 -ENQNLLIQ----VEEVSQTCSKSEIHNEKEKCFI 903
Score = 34.3 bits (77), Expect = 0.24
Identities = 65/310 (20%), Positives = 125/310 (40%), Gaps = 50/310 (16%)
Query: 94 RFSSVPLDPMERPMSQAD----------LELDYNPPRVQLSDEMFVFQDGRWVNENCRLQ 143
R +V + MSQA+ LE+ + +++L D Q V+E LQ
Sbjct: 1326 RVHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQLKIKLQDSQNNLQIN--VSELQTLQ 1383
Query: 144 SPYFSPSASFHHKLHHKRLAKECMLQEENKSLREENKALREEN----RMLSKENKILQVF 199
S + H+K+ + ++KE L+E+ S++ EN ++ E+ L+ +N++L+
Sbjct: 1384 SEH-DTLLERHNKMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVLRNS 1442
Query: 200 WEEHKASLGREESRAPSPLLHKDSASLEV---VKKDHVALQVPRGKEDSTLQLLREENRA 256
+ + L +EE R L + + +E K+ + P + S L+ LRE
Sbjct: 1443 FRDQVRHL-QEEHRKTVETLQQQLSKMEAQLFQLKNEPTTRSPVSSQQS-LKNLRERRNT 1500
Query: 257 LQQLLEQKQAYWAQAEDTAAPAEESKPAPSPHEEPCSPGLLQDQGSGLSSRFEEP--KGP 314
LL+ + E ES + S + + L+ + ++ E P
Sbjct: 1501 DLPLLDMHTVTREEGEGMETTDTESVSSASTYTQS-----LEQLLNSPETKLEPPLWHAE 1555
Query: 315 PARQEDSKELRALRKMVSNMSGPSGEEEAKVGPGLPDGCQPLQLLREMRQALQALLKENR 374
++E ++L + K +++G LLRE L+++ +
Sbjct: 1556 FTKEELVQKLSSTTKSADHLNG---------------------LLRETEATNAILMEQIK 1594
Query: 375 LLQEENRTLQ 384
LL+ E R L+
Sbjct: 1595 LLKSEIRRLE 1604
Score = 28.9 bits (63), Expect = 9.9
Identities = 58/267 (21%), Positives = 101/267 (37%), Gaps = 47/267 (17%)
Query: 159 HKRLAKECMLQEENKS-----LREENKALREENRMLSKENKILQVFWEEHKASLGREESR 213
++RL KE + NK+ L +E K +++ L +E LQ ++++ E++
Sbjct: 1165 YERLMKELNQKLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYE-----EKNT 1219
Query: 214 APSPLL---HKDSASLEVVKKDHVALQVPRGKEDSTLQLLREENRALQQLLEQKQAYWAQ 270
LL K+ A + + DH+ LQ L+ E A QQ +E + A+
Sbjct: 1220 KIKQLLVKTKKELADSKQAETDHLILQAS----------LKGELEASQQQVEVYKIQLAE 1269
Query: 271 AEDTAAPAEES-KPAPSPHEEPCSPGLLQDQGSGLSSRFEEPKGPPARQEDSKELRALR- 328
E K + H+ S Q + + L K A E +R
Sbjct: 1270 ITSEKHKIHEHLKTSAEQHQRTLSA--YQQRVTALQEECRAAKAEQATVTSEFESYKVRV 1327
Query: 329 ----KMVSNMSGPSGEEEAKVGPGLPDGCQPLQLLREMRQALQALLKENRL-LQEENRTL 383
K N S E E ++ R+ L+ L+ + ++ LQ+ L
Sbjct: 1328 HNVLKQQKNKSMSQAETEGA---------------KQEREHLEMLIDQLKIKLQDSQNNL 1372
Query: 384 QVLRAEHRGFQEENKALWENNKLKLQQ 410
Q+ +E + Q E+ L E + LQ+
Sbjct: 1373 QINVSELQTLQSEHDTLLERHNKMLQE 1399
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 48.1 bits (113), Expect = 2e-05
Identities = 68/265 (25%), Positives = 107/265 (40%), Gaps = 23/265 (8%)
Query: 152 SFHHKLHHKRLAKECMLQEENKSLREENKALREENRMLSKENKILQVFWEEHKASLGREE 211
S KL +++ E L K L EE L ++N L+KE K+L+ E +L EE
Sbjct: 957 SARQKLQLEKVTTEAKL----KKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEE 1012
Query: 212 SRAPS--PLLHKDSASLEVVKKDHVALQVPRGKEDSTLQLLREENRALQQLLEQKQAYWA 269
++ S L +K A + +++ + R + + T + L ++ L + + QA A
Sbjct: 1013 EKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIA 1072
Query: 270 QAEDTAAPAEESKPA--PSPHEEPCSPGLLQDQGSGLSSRFEEPKGPPARQEDSKELRAL 327
+ + A EE A EE + + L S+ E QED + RA
Sbjct: 1073 ELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISE------LQEDLESERAS 1126
Query: 328 RKMVSNMSGPSGEEEAKVGPGLP---DGCQPLQLLREMRQALQALLKENRLLQEENRT-- 382
R GEE + L D Q LR R+ +LK + L+EE +T
Sbjct: 1127 RNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILK--KTLEEEAKTHE 1184
Query: 383 --LQVLRAEHRGFQEENKALWENNK 405
+Q +R +H EE E K
Sbjct: 1185 AQIQEMRQKHSQAVEELAEQLEQTK 1209
Score = 32.3 bits (72), Expect = 0.89
Identities = 70/293 (23%), Positives = 114/293 (38%), Gaps = 29/293 (9%)
Query: 148 SPSASFHHKLHHKRLAKECMLQEENKSLREENKALREENRMLSKENKILQVFWEEHKASL 207
S S S KL A E LQ+ + L+EEN+ + LS K+ QV E++
Sbjct: 1290 SQSDSKSSKLTKDFSALESQLQDTQELLQEENR------QKLSLSTKLKQVEDEKNSFRE 1343
Query: 208 GREESRAPSPLLHKDSASLEVVKKDHVALQVPRGKEDST--LQLLREENRALQQLLEQKQ 265
EE L K A+L D + + EDS L+ E R LQ+ LE
Sbjct: 1344 QLEEEEEAKHNLEKQIATLHAQVAD-----MKKKMEDSVGCLETAEEVKRKLQKDLEGLS 1398
Query: 266 AYWAQAEDTAAPAEESKPAPSPHEEPCSPGLLQDQGSGLSSRFEEPKGPPARQEDSKELR 325
E AA + K +E L D L + + +Q+ +L
Sbjct: 1399 Q--RHEEKVAAYDKLEKTKTRLQQE------LDDLLVDLDHQRQSACNLEKKQKKFDQLL 1450
Query: 326 ALRKMVSNMSGPSGEEEAKVGPGLPDGCQPLQLLREMRQALQALLKENRLLQEENRTLQV 385
A K +S + + E + + L L R + +A++ + RL ++ ++
Sbjct: 1451 AEEKTIS--AKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMED 1508
Query: 386 LRAEHRGFQEENKALWENNKLKLQQKLVIDTVTEVTARMEMLIEELYAFMPAR 438
L + + L E +K L+Q+ V E+ ++E L +EL A A+
Sbjct: 1509 LMSSKDDVGKSVHEL-EKSKRALEQQ-----VEEMKTQLEELEDELQATEDAK 1555
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 47.4 bits (111), Expect = 3e-05
Identities = 77/322 (23%), Positives = 130/322 (40%), Gaps = 48/322 (14%)
Query: 155 HKLHHKRLAKECMLQEENKSLREENKALREENRMLSKENKILQVFWEEHKASLGREESRA 214
H+ K +E MLQE+ K EE K + E MLS ++K Q + +E + +L E SR
Sbjct: 1497 HQAGEKLSPEEEMLQEDKKLKWEEWKQVWEN--MLSSKSKEQQ-YKDEEEVTLEEEVSRE 1553
Query: 215 PSPLLHKDSASLEVVKKDHVALQVPRGKEDSTLQLLREENRALQQ--LLEQKQAYWAQAE 272
+ + ++++H ++ R + + + +EE + Q+ L Q++ AQ E
Sbjct: 1554 GEEKEQQVTEEQRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEE 1613
Query: 273 DTAAPAEESKPAPSPHEEPCSPGLLQDQGSGLSSRFEEPKGPPARQEDSKELRALRKMVS 332
A A K E + G + L+ R G QE K + +K+
Sbjct: 1614 RKLAQAYV-KITQDDREMAQAEGKFAQKEETLAQR-----GEKLSQEAEKLAQKRKKLAK 1667
Query: 333 NMSGPSGEEEAKVGPG----------------LPDGCQPLQLL-REMRQALQAL------ 369
+ EEE G LP Q L +E+ Q L+ L
Sbjct: 1668 KWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEE 1727
Query: 370 --LKENRLLQEENRTLQVLRAEHRGFQEENKAL-WENNKLKLQQKLVIDTVTEVTARMEM 426
KE L QEE + ++ E + EE +AL W+ KL ++ T++ E+
Sbjct: 1728 LSWKEEELNQEEGKLVE----EKKKLAEEEEALAWQREKLSEEE-------TKLAQEEEL 1776
Query: 427 LIEELYAFMPARSQDPKKPSRV 448
LI+E + + P++ R+
Sbjct: 1777 LIQEKEKLAQHKEKMPEEEERL 1798
Score = 37.0 bits (84), Expect = 0.036
Identities = 65/273 (23%), Positives = 106/273 (38%), Gaps = 42/273 (15%)
Query: 168 LQEENKSLREENKALREENRMLSKENKILQVFWEEHKASLGREESRAPSPLLHKDSASLE 227
+QEE+K R K R E + +E K+ Q EE K L +EE + A ++
Sbjct: 1568 IQEEHKWARIHRKRARAEKKRAQEERKLAQ---EEEK--LAQEERQLAQEERKLAQAYVK 1622
Query: 228 VVKKDHVALQVPRGKEDSTLQLLREENRALQQ---LLEQKQAYWAQAEDTAAPAEESKPA 284
+ + D Q GK + L + L Q L QK+ A+ + A EE
Sbjct: 1623 ITQDDREMAQA-EGKFAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAK 1681
Query: 285 PSPHEEPCSPGLLQDQGSGLSSRFEE-PKGPPARQEDSKEL-RALRKMVSNMSGPSGEEE 342
G L + + L+ + EE P+ KEL + L ++ +M S +EE
Sbjct: 1682 KG--------GKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEE 1733
Query: 343 AKVGPGLPDGCQPLQLLREMRQALQALLKENRLLQEENRTL-----QVLRAEHRGFQEEN 397
E+ Q L++E + L EE L ++ E + QEE
Sbjct: 1734 ------------------ELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEE 1775
Query: 398 KALWENNKLKLQQKLVIDTVTEVTARMEMLIEE 430
+ E KL ++ + + + + E LIE+
Sbjct: 1776 LLIQEKEKLAQHKEKMPEEEERLGRKREQLIEK 1808
Score = 35.8 bits (81), Expect = 0.081
Identities = 59/272 (21%), Positives = 119/272 (43%), Gaps = 28/272 (10%)
Query: 164 KECMLQEENKSLREENKAL-REENRMLSKENKILQVFWEEHKASLGREESRAPSPLLHKD 222
KE M +EE ++ ++ L EE +++ K+ K + +F E ++G+E S+ +
Sbjct: 1340 KEVMPREEEQAQKKARDMLGLEETQVILKKGKKV-IFLEPGNVTMGKEISKKEEKKTFQK 1398
Query: 223 S--ASLEVVKKDHVALQVPR--GKEDSTLQLLREENRALQQLLEQKQAYWAQAEDTAAPA 278
S + V+K+ ++ R KE+ + EE L++ + +++ E T +
Sbjct: 1399 SPKQGRKAVQKERKVGKIKREMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQ 1458
Query: 279 E-------------ESKPAPSPHEEPCSPGLLQDQGSGLSSRFEEPKGPPARQEDSK-EL 324
+ E++ + +E LLQ++ + + QED K +
Sbjct: 1459 DWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKW 1518
Query: 325 RALRKMVSNM-SGPSGEEEAKVGPGLPDGCQPLQLLREMRQALQALLKENRLLQEENRTL 383
+++ NM S S E++ K + ++ RE + Q + +E R +QEE++
Sbjct: 1519 EEWKQVWENMLSSKSKEQQYK---DEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWA 1575
Query: 384 QV----LRAEHRGFQEENKALWENNKLKLQQK 411
++ RAE + QEE K E KL +++
Sbjct: 1576 RIHRKRARAEKKRAQEERKLAQEEEKLAQEER 1607
Score = 30.0 bits (66), Expect = 4.4
Identities = 45/231 (19%), Positives = 90/231 (38%), Gaps = 21/231 (9%)
Query: 167 MLQEENKSLREENKALREENRMLSKENKILQVFWEEHKASLGREESRAPSPLLHKDSASL 226
+ ++E K R++ K + RM++KE K+ E ++ L R+ S +
Sbjct: 2132 LTKDEKKLARKQRKLANKMRRMINKEEKM-----TEEESKLARKHSEVILDDEEEGGIEE 2186
Query: 227 EVV----------KKDHVALQVPRGKEDSTLQLLREE---NRALQQLLE--QKQAYWAQA 271
E V +K+ P+ K S + + E + ++ LL+ +KQ +
Sbjct: 2187 EEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSE 2246
Query: 272 EDTAAPAEESKPAPSPHEEPCSPGLLQDQGSGLSSRFEEPKGPPARQEDSKELRALRKMV 331
E+ EE + EE ++ + EE K +++ +E++ ++
Sbjct: 2247 EEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVF 2306
Query: 332 SNMSGPSGEEEAKVGPGLPDGCQPLQLLREMRQALQALLKENRL-LQEENR 381
EEE + + + L E+ + + L KE + LQE+ R
Sbjct: 2307 EEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRR 2357
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 46.6 bits (109), Expect = 5e-05
Identities = 69/285 (24%), Positives = 120/285 (42%), Gaps = 37/285 (12%)
Query: 156 KLHHKRLAKECMLQEENKSLREENKALREENRMLSKENKILQ-------VFWEEHKASLG 208
K+ KRL + L++ENKSL +E L ++ + L KENK L+ EE+ +G
Sbjct: 804 KISSKRLEQ---LEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIG 860
Query: 209 REESRAPSPL----LHKDSA-SLEVVKKDHVALQVPRGKEDSTLQLLREE---------- 253
E + ++K+S L+ ++K++ L + TL LRE+
Sbjct: 861 NLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQ 920
Query: 254 -NRALQQLLEQKQAYWAQAE-----DTAAPAEESKPAPSPHEEPCSPGL--LQDQGSGLS 305
N L++L + + E + + K S E L +++ + L
Sbjct: 921 MNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALE 980
Query: 306 SRFEEPKGPPARQEDSKELRALRKMVSNMSGPSGEEEAKVGPGLPDGCQPLQLLREMRQA 365
+R EE Q+ +EL+ ++K + +EE V P + + RE ++
Sbjct: 981 ARLEESTN--YNQQLRQELKTVKKNYEALKQRQ-DEERMVQSSPPISGEDNKWERESQET 1037
Query: 366 LQALLKENRLLQEENRTLQVLRAEHRGFQEENKAL-WENNKLKLQ 409
+ LLK L E R L+AE + + + K L +NN L+ Q
Sbjct: 1038 TRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQ 1082
Score = 40.8 bits (94), Expect = 0.003
Identities = 67/301 (22%), Positives = 121/301 (40%), Gaps = 68/301 (22%)
Query: 148 SPSASFHHKLHHKRLAKECMLQEENKSLREENKALR-----------------EENRMLS 190
+P S H+++ ++ L+ EN+SL + + LR +EN+ LS
Sbjct: 445 APQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLS 504
Query: 191 KENKILQVFWEEHKASLGREESRAPSPLLHKDSASLEVVKKDHVALQVPRGKEDSTLQLL 250
K+ +IL+ + K SL + + S L K+ A LE ++ R + +++L
Sbjct: 505 KKVEILENEIVQEKQSL--QNCQNLSKDLMKEKAQLEKT------IETLRENSERQIKIL 556
Query: 251 REENRALQQLLEQKQAYWAQAEDTAAPAEESKPAPSPHEEPCSPGLLQDQGSGLSS-RFE 309
+EN L Q + + +Q A + K HE +++ S LS FE
Sbjct: 557 EQENEHLNQTVSSLRQR-SQISAEARVKDIEKENKILHES------IKETSSKLSKIEFE 609
Query: 310 EPKGPPARQEDSKELRALRKMVSNMSGPSGEEEAKVGPGLPDGCQPLQLLREMRQALQAL 369
+++ KEL ++ GE E+ L L
Sbjct: 610 -------KRQIKKELEHYKE--------KGERA-----------------EELENELHHL 637
Query: 370 LKENRLLQEENRTLQVLRAEHRGFQEENKALWENNKLKLQQKLVIDTVTEVTARMEMLIE 429
KEN LLQ++ L++ + ++EN L N+ + K +D+ +T ++E L +
Sbjct: 638 EKENELLQKKITNLKITCEKIEALEQENSELERENR---KLKKTLDSFKNLTFQLESLEK 694
Query: 430 E 430
E
Sbjct: 695 E 695
Score = 32.7 bits (73), Expect = 0.68
Identities = 64/292 (21%), Positives = 119/292 (40%), Gaps = 32/292 (10%)
Query: 138 ENCRLQ---SPYFSPSASFHHKLHHKRLAKECMLQEENKSLREENKALREENRMLSKENK 194
+N +LQ S S S S ++ + + L ++ L+ EN+S+ +E + L+ L K+++
Sbjct: 1103 QNAKLQVENSTLNSQSTSLMNQ-NAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHE 1161
Query: 195 ILQVFWEEHKASLGREESRAPSPLLHKDSASLEVVKKD----HVALQVPRGKEDSTLQLL 250
L++ E + E + L +LEV +D + L +G+ + ++L
Sbjct: 1162 KLELLHERQASEY--ESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKML 1219
Query: 251 REENRALQQLLEQKQAYWAQAEDTAAPAEESKPAPSPHEEPCSPGLLQDQGSGLSSRFEE 310
+ E + LLE K AE E + + + +LQ L S
Sbjct: 1220 KVEQEKM--LLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNN 1277
Query: 311 PKGPPARQEDSKELRALRKMVSNMSGPSGEEEAKVGPGLPDGCQPLQLL--------REM 362
K R E E L++ + S + L + C+ L L R +
Sbjct: 1278 SKLEQTRLE--AEFSKLKEQYQQLDITSTK--------LNNQCELLSQLKGNLEEENRHL 1327
Query: 363 RQALQALLKENRLLQEEN-RTLQVLRAEHRGFQEENKALWENNKLKLQQKLV 413
+Q L+ +NR L E+N + + E R + ++ L K KL++K++
Sbjct: 1328 LDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNEL-RRQKEKLEEKIM 1378
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 45.4 bits (106), Expect = 1e-04
Identities = 71/291 (24%), Positives = 124/291 (42%), Gaps = 37/291 (12%)
Query: 166 CMLQEENKSLREENKALREEN----RMLSKENKILQVFWEEHKASLGREESRAPSPLLHK 221
C LQEE + LRE+N+ +RE + + ++ K+ +++ + L S L +
Sbjct: 243 CSLQEEQQQLREQNELIRERSEKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEE 302
Query: 222 DSASLEVVKKDHVALQVPRGKE-DSTLQLLREENR-------ALQQLLEQKQAYWAQAED 273
LE+ K+ + LQ+ E + ++LL ++ AL+Q LE+ +A Q
Sbjct: 303 KKVRLELEKE--LELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFH 360
Query: 274 TAAPAEESKPAPSPHEEPCSPGLLQDQGSGLSSRFEEPKGPPARQEDSKELRALRKMVSN 333
A AE S +E S +Q + EE R E R+ K+
Sbjct: 361 KAQNAESS--LQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERARQGAEERS-HKLQQE 417
Query: 334 MSGPSGEEEAKVGPGLPDGC----QPLQLLREMRQALQALLKENR----LLQEENRTLQV 385
+ G G + ++ L + C + L+ +E RQALQ L+ + LL+ E + ++
Sbjct: 418 LGGRIGALQLQLSQ-LHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSLLRMELQQVEG 476
Query: 386 LRAEHRGFQ-----------EENKALWENNKLKLQQKLVIDTVTEVTARME 425
L+ E R Q E+ +AL E Q KL ++ + EV ++
Sbjct: 477 LKKELRELQDEKAELQKICEEQEQALQEMGLHLSQSKLKMEDIKEVNQALK 527
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 45.4 bits (106), Expect = 1e-04
Identities = 71/291 (24%), Positives = 124/291 (42%), Gaps = 37/291 (12%)
Query: 166 CMLQEENKSLREENKALREEN----RMLSKENKILQVFWEEHKASLGREESRAPSPLLHK 221
C LQEE + LRE+N+ +RE + + ++ K+ +++ + L S L +
Sbjct: 243 CSLQEEQQQLREQNELIRERSEKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEE 302
Query: 222 DSASLEVVKKDHVALQVPRGKE-DSTLQLLREENR-------ALQQLLEQKQAYWAQAED 273
LE+ K+ + LQ+ E + ++LL ++ AL+Q LE+ +A Q
Sbjct: 303 KKVRLELEKE--LELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFH 360
Query: 274 TAAPAEESKPAPSPHEEPCSPGLLQDQGSGLSSRFEEPKGPPARQEDSKELRALRKMVSN 333
A AE S +E S +Q + EE R E R+ K+
Sbjct: 361 KAQNAESS--LQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERARQGAEERS-HKLQQE 417
Query: 334 MSGPSGEEEAKVGPGLPDGC----QPLQLLREMRQALQALLKENR----LLQEENRTLQV 385
+ G G + ++ L + C + L+ +E RQALQ L+ + LL+ E + ++
Sbjct: 418 LGGRIGALQLQLSQ-LHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSLLRMELQQVEG 476
Query: 386 LRAEHRGFQ-----------EENKALWENNKLKLQQKLVIDTVTEVTARME 425
L+ E R Q E+ +AL E Q KL ++ + EV ++
Sbjct: 477 LKKELRELQDEKAELQKICEEQEQALQEMGLHLSQSKLKMEDIKEVNQALK 527
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
sapiens]
Length = 708
Score = 45.4 bits (106), Expect = 1e-04
Identities = 71/291 (24%), Positives = 124/291 (42%), Gaps = 37/291 (12%)
Query: 166 CMLQEENKSLREENKALREEN----RMLSKENKILQVFWEEHKASLGREESRAPSPLLHK 221
C LQEE + LRE+N+ +RE + + ++ K+ +++ + L S L +
Sbjct: 351 CSLQEEQQQLREQNELIRERSEKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEE 410
Query: 222 DSASLEVVKKDHVALQVPRGKE-DSTLQLLREENR-------ALQQLLEQKQAYWAQAED 273
LE+ K+ + LQ+ E + ++LL ++ AL+Q LE+ +A Q
Sbjct: 411 KKVRLELEKE--LELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFH 468
Query: 274 TAAPAEESKPAPSPHEEPCSPGLLQDQGSGLSSRFEEPKGPPARQEDSKELRALRKMVSN 333
A AE S +E S +Q + EE R E R+ K+
Sbjct: 469 KAQNAESS--LQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERARQGAEERS-HKLQQE 525
Query: 334 MSGPSGEEEAKVGPGLPDGC----QPLQLLREMRQALQALLKENR----LLQEENRTLQV 385
+ G G + ++ L + C + L+ +E RQALQ L+ + LL+ E + ++
Sbjct: 526 LGGRIGALQLQLSQ-LHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSLLRMELQQVEG 584
Query: 386 LRAEHRGFQ-----------EENKALWENNKLKLQQKLVIDTVTEVTARME 425
L+ E R Q E+ +AL E Q KL ++ + EV ++
Sbjct: 585 LKKELRELQDEKAELQKICEEQEQALQEMGLHLSQSKLKMEDIKEVNQALK 635
>gi|50980301 myosin phosphatase-Rho interacting protein isoform 2
[Homo sapiens]
Length = 1025
Score = 45.4 bits (106), Expect = 1e-04
Identities = 51/217 (23%), Positives = 98/217 (45%), Gaps = 29/217 (13%)
Query: 167 MLQEENKSLREENKALREENRMLSKENKILQVFWEEHKASLGREESRAPSPLLHKDSASL 226
+L++E + ++E L E+NR+L + ++ +LGRE+S +L
Sbjct: 678 LLEKELEQSQKEASDLLEQNRLLQDQLRV----------ALGREQSAREGYVLQA----- 722
Query: 227 EVVKKDHVALQVPRGKEDSTLQLLREENRALQQLLEQKQAYWAQAEDTAAPAEESKPAPS 286
++ A++ K+ LQ R+ R L++L E+K A E+TAA + +
Sbjct: 723 -TCERGFAAMEETHQKKIEDLQ--RQHQRELEKLREEKDRLLA--EETAATISAIEAMKN 777
Query: 287 PHEEPCSPGLLQDQGSGLSSRFEEPKGPPARQEDSKELRALRKMVSNMSGPSGEEEAKVG 346
H E L + Q S +SS + + R++ +EL+++++ + +S ++
Sbjct: 778 AHREEMERELEKSQRSQISSVNSDVEA--LRRQYLEELQSVQRELEVLSEQYSQK----- 830
Query: 347 PGLPDGCQPLQLLREMRQALQALLKENRLLQEENRTL 383
+ Q L RQAL+ +EN+ L N+ L
Sbjct: 831 --CLENAHLAQALEAERQALRQCQRENQELNAHNQEL 865
>gi|50980307 myosin phosphatase-Rho interacting protein isoform 1
[Homo sapiens]
Length = 1038
Score = 45.4 bits (106), Expect = 1e-04
Identities = 51/217 (23%), Positives = 98/217 (45%), Gaps = 29/217 (13%)
Query: 167 MLQEENKSLREENKALREENRMLSKENKILQVFWEEHKASLGREESRAPSPLLHKDSASL 226
+L++E + ++E L E+NR+L + ++ +LGRE+S +L
Sbjct: 678 LLEKELEQSQKEASDLLEQNRLLQDQLRV----------ALGREQSAREGYVLQA----- 722
Query: 227 EVVKKDHVALQVPRGKEDSTLQLLREENRALQQLLEQKQAYWAQAEDTAAPAEESKPAPS 286
++ A++ K+ LQ R+ R L++L E+K A E+TAA + +
Sbjct: 723 -TCERGFAAMEETHQKKIEDLQ--RQHQRELEKLREEKDRLLA--EETAATISAIEAMKN 777
Query: 287 PHEEPCSPGLLQDQGSGLSSRFEEPKGPPARQEDSKELRALRKMVSNMSGPSGEEEAKVG 346
H E L + Q S +SS + + R++ +EL+++++ + +S ++
Sbjct: 778 AHREEMERELEKSQRSQISSVNSDVEA--LRRQYLEELQSVQRELEVLSEQYSQK----- 830
Query: 347 PGLPDGCQPLQLLREMRQALQALLKENRLLQEENRTL 383
+ Q L RQAL+ +EN+ L N+ L
Sbjct: 831 --CLENAHLAQALEAERQALRQCQRENQELNAHNQEL 865
>gi|51944974 tumor suppressor candidate 1 [Homo sapiens]
Length = 212
Score = 45.1 bits (105), Expect = 1e-04
Identities = 47/146 (32%), Positives = 64/146 (43%), Gaps = 22/146 (15%)
Query: 171 ENKSLREENKALREENRMLSKENKILQVFWEEHKASLGREESRAPSPLLHKDSASLEVVK 230
+N LR+EN LR ENR L +EN+ SL R+ R P + A V
Sbjct: 85 QNARLRQENARLRLENRRLKRENR-----------SLFRQALRLPGEGGNGTPAEARRVP 133
Query: 231 KDHVALQVPRGKEDSTLQLLREENRALQQLLEQKQAYWAQAEDTAAPAEESKPAPS--PH 288
++ R DS + RAL+ LE+ +A + +A E+ P PS
Sbjct: 134 EE---ASTNRRARDSGREDEPGSPRALRARLEKLEAMYRRAL-LQLHLEQRGPRPSGDKE 189
Query: 289 EEPCSPGLLQDQGSGLSSRFEEPKGP 314
E+P LQ+ SGL SR EP GP
Sbjct: 190 EQP-----LQEPDSGLRSRDSEPSGP 210
>gi|156766068 CDC42 binding protein kinase gamma (DMPK-like) [Homo
sapiens]
Length = 1551
Score = 44.7 bits (104), Expect = 2e-04
Identities = 69/272 (25%), Positives = 110/272 (40%), Gaps = 54/272 (19%)
Query: 168 LQEENKSLREENKALREENRMLSKENKILQVFWEE-----------HKAS----LGREES 212
L + + R + L + LS++ LQ WE+ H AS +G E
Sbjct: 543 LSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTIHTASETNGMGPPEG 602
Query: 213 RAPSPLLHKDSASL-EVVKKDHVALQVPRGKEDSTLQLLREENRALQQLLEQKQAYWAQA 271
L K+ A+L E +++ H P GKE++ QL +EENR L + E+ +A AQ
Sbjct: 603 GPQEAQLRKEVAALREQLEQAHS--HRPSGKEEALCQL-QEENRRLSREQERLEAELAQE 659
Query: 272 EDTAAPAEESKPAPSPH-------------EEPCSPGLLQDQGSGLSSRFEEPKGP---- 314
+++ E + + +E S G LQ + ++ E +
Sbjct: 660 QESKQRLEGERRETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQT 719
Query: 315 -PARQEDSK-ELRALRKMVSN-----MSGPSGEEEAKVGPGLPDGCQPLQLLREMRQALQ 367
PAR D + + R L+KM ++ S E AK G L + Q +
Sbjct: 720 LPARPLDHQWKARRLQKMEASARLELQSALEAEIRAKQG-----------LQERLTQVQE 768
Query: 368 ALLKENRLLQEENRTLQVLRAEHRGFQEENKA 399
A L+ R LQE + Q L+ E +EE +A
Sbjct: 769 AQLQAERRLQEAEKQSQALQQELAMLREELRA 800
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 44.7 bits (104), Expect = 2e-04
Identities = 66/271 (24%), Positives = 108/271 (39%), Gaps = 52/271 (19%)
Query: 150 SASFHHKLHHKRLAKECMLQEENKSLREENKALREENRMLSKENKILQVFWEEHKASLGR 209
S F K K + + +E KSLRE+ LR++N L +N L +E L
Sbjct: 209 STDFQKKPRDKMFSSSAPVDQEIKSLREKLNKLRQQNACLVTQNHSLMTKFESIHFEL-- 266
Query: 210 EESRAPSPLL---HKDSASLEVVKKDHVALQVPRGKEDSTLQLLREENRALQQLLEQKQA 266
+SRA +L + +AS+ ++++ + L+ +D L R + LEQ Q
Sbjct: 267 TQSRAKVSMLESAQQQAASVPILEEQIINLEAEVSAQDKVL-------REAENKLEQSQK 319
Query: 267 YWAQAEDTAAPAEESKPAPSPHEEPC---SPGLLQDQGSGLSSRFEEPKGPPARQEDSKE 323
+ E + +ESK E C LL+ G + + + +E SK
Sbjct: 320 MVIEKEQS---LQESK-------EECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKA 369
Query: 324 LRALRKMVS-NMSGPSGEEEAKVGPGLPDGCQPLQLLREMRQALQALLKENRLLQEE--- 379
+ +K V+ + EEE + + L KEN+ LQE
Sbjct: 370 FQQYKKKVAEKLEKVQAEEEI------------------LERNLTNCEKENKRLQERCGL 411
Query: 380 -NRTLQVLRAEHRGFQEENKALWENNKLKLQ 409
L++L+ + R +EEN N K KL+
Sbjct: 412 YKSELEILKEKLRQLKEEN----NNGKEKLR 438
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 44.3 bits (103), Expect = 2e-04
Identities = 63/329 (19%), Positives = 139/329 (42%), Gaps = 34/329 (10%)
Query: 109 QADLELDYNPPRVQLSDEMFVFQDGRWVNENCRLQSPYFSPSASFHHKLHHKRLAKECML 168
+++++L+ + +L + + E RL S SA ++ L
Sbjct: 234 KSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ 293
Query: 169 QEENKSLREENKALREENRMLSKENKILQ----VFWEEHKASLGREESRAPSPLLHKDSA 224
Q+E K R+E K +E +M +E KI + ++ +E K E+ R + +
Sbjct: 294 QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE- 352
Query: 225 SLEVVKKDHVALQVPRGKEDSTLQLLREENRALQQLLEQKQAYWAQAEDTAAPAEESKPA 284
E +++ ++ K + +RE++ +Q EQ++ W Q E E+ +
Sbjct: 353 --EKIREQEEKIREQEEKMWRQEEKIREQDEKIQ---EQEEEMWRQEEKIREQEEKRQEK 407
Query: 285 PSPHEEPCSPGLLQDQGSGLSSRFEEPKGPPARQEDSKELRALRKMVSNMSGPSGEEEAK 344
E+ +++Q + + EE RQE+ ++R L +M+ + E E K
Sbjct: 408 MWRQEKK-----MREQDEKIREQEEE----MWRQEE--KIRELEEMMQDQEEKLREVEEK 456
Query: 345 VGPGLPDGCQPLQLLREMRQALQALLKENRLLQEENRTL---QVLRAEHRGFQEENKALW 401
+ + + ++E + +Q +E ++ ++E +T ++L+ E + +++E K +W
Sbjct: 457 MQ-------EEEEKMQEQEEKIQR--QEEKIQEQEEKTWRQEKLLKQEEKIWEQEEK-MW 506
Query: 402 ENNKLKLQQKLVIDTVTEVTARMEMLIEE 430
+ +Q+ + E R E + E
Sbjct: 507 RQEEKMWEQEEKMQEQEEKMQRQEEKMRE 535
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 44.3 bits (103), Expect = 2e-04
Identities = 63/329 (19%), Positives = 139/329 (42%), Gaps = 34/329 (10%)
Query: 109 QADLELDYNPPRVQLSDEMFVFQDGRWVNENCRLQSPYFSPSASFHHKLHHKRLAKECML 168
+++++L+ + +L + + E RL S SA ++ L
Sbjct: 234 KSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQ 293
Query: 169 QEENKSLREENKALREENRMLSKENKILQ----VFWEEHKASLGREESRAPSPLLHKDSA 224
Q+E K R+E K +E +M +E KI + ++ +E K E+ R + +
Sbjct: 294 QQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQE- 352
Query: 225 SLEVVKKDHVALQVPRGKEDSTLQLLREENRALQQLLEQKQAYWAQAEDTAAPAEESKPA 284
E +++ ++ K + +RE++ +Q EQ++ W Q E E+ +
Sbjct: 353 --EKIREQEEKIREQEEKMWRQEEKIREQDEKIQ---EQEEEMWRQEEKIREQEEKRQEK 407
Query: 285 PSPHEEPCSPGLLQDQGSGLSSRFEEPKGPPARQEDSKELRALRKMVSNMSGPSGEEEAK 344
E+ +++Q + + EE RQE+ ++R L +M+ + E E K
Sbjct: 408 MWRQEKK-----MREQDEKIREQEEE----MWRQEE--KIRELEEMMQDQEEKLREVEEK 456
Query: 345 VGPGLPDGCQPLQLLREMRQALQALLKENRLLQEENRTL---QVLRAEHRGFQEENKALW 401
+ + + ++E + +Q +E ++ ++E +T ++L+ E + +++E K +W
Sbjct: 457 MQ-------EEEEKMQEQEEKIQR--QEEKIQEQEEKTWRQEKLLKQEEKIWEQEEK-MW 506
Query: 402 ENNKLKLQQKLVIDTVTEVTARMEMLIEE 430
+ +Q+ + E R E + E
Sbjct: 507 RQEEKMWEQEEKMQEQEEKMQRQEEKMRE 535
>gi|38176300 nestin [Homo sapiens]
Length = 1621
Score = 43.9 bits (102), Expect = 3e-04
Identities = 69/271 (25%), Positives = 119/271 (43%), Gaps = 48/271 (17%)
Query: 160 KRLAKECMLQEENKSLREEN-KALREEN----RMLSKENKILQVFWEEHKASLGREESRA 214
K L +E +QE K+L ++ + L EN R L ++ + L+ +E+K L
Sbjct: 547 KSLGEE--IQESLKTLENQSHETLERENQECPRSLEEDLETLKSLEKENKELL------- 597
Query: 215 PSPLLHKDSASLEVVKKDHVALQVPRGKEDS-TLQLLREENRALQQLLEQKQAYWAQAED 273
KD + ++K+ V P GKED+ TLQ L++EN+ L + LE E
Sbjct: 598 ------KDVEVVRPLEKEAVGQLKPTGKEDTQTLQSLQKENQELMKSLE------GNLET 645
Query: 274 TAAPAEESKPAPSPHEEPCSPGLLQDQGSGLSSRFEEPKGPPARQEDSKELRALRKMVSN 333
P E++ S LQ+ L++ E+ P R + + ALR +
Sbjct: 646 FLFPGTENQELVSS---------LQENLESLTA-LEKENQEPLRSPEVGDEEALRPLTKE 695
Query: 334 MSGP--SGEEEAKVG--PGLPDGCQPLQLLREMRQALQALL-----KENRLLQEENRTLQ 384
P S E+E K + +PL+ L E Q++ L K R L+E+++ +
Sbjct: 696 NQEPLRSLEDENKEAFRSLEKENQEPLKTLEEEDQSIVRPLETENHKSLRSLEEQDQ--E 753
Query: 385 VLRAEHRGFQEENKALWENNKLKLQQKLVID 415
LR + Q+ ++L E +++ L+ +D
Sbjct: 754 TLRTLEKETQQRRRSLGEQDQMTLRPPEKVD 784
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 43.5 bits (101), Expect = 4e-04
Identities = 69/284 (24%), Positives = 103/284 (36%), Gaps = 50/284 (17%)
Query: 173 KSLREENKALREENRMLSKENKILQVFWEEHKASLGREESRAPSPLLHKDSASLEVVKKD 232
K E+ L ++N LSKE K+L+ E + EE + S L+K E D
Sbjct: 1006 KKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKS--LNKLRLKYEATIAD 1063
Query: 233 HVALQVPRGKEDSTLQLLREENRAL--------QQLLEQKQAYWAQAEDTAAPAEESKPA 284
++ KE+ Q L + R L +Q++EQ+Q AEE +
Sbjct: 1064 ---MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQR-----------AEELRAQ 1109
Query: 285 PSPHEEPCSPGLLQDQGSG------LSSRFEEPKGPPARQEDSKELRALRKMVSNMSGPS 338
EE L + + G L S E QED + R R
Sbjct: 1110 LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDL 1169
Query: 339 GEEEAKVGPGLPDGCQPLQLLREMRQALQALLKE-NRLLQEENR----TLQVLRAEHRGF 393
GEE + L D +E+R + + E + L+EE R +Q LR H
Sbjct: 1170 GEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQA 1229
Query: 394 QEE----------NKALWENNKLKLQQKLVIDTVTEVTARMEML 427
E K WE +L L+ + V+E+ A + L
Sbjct: 1230 LGELAEQLEQARRGKGAWEKTRLALEAE-----VSELRAELSSL 1268
Score = 40.0 bits (92), Expect = 0.004
Identities = 64/253 (25%), Positives = 102/253 (40%), Gaps = 36/253 (14%)
Query: 173 KSLREENKALREENRMLSKENKILQVFWEEHKASLGREESRAPSPL---LHKDSASLEV- 228
KSLRE AL E L E ++ + E+ + LG E L L +A E+
Sbjct: 1136 KSLREAQAALAEAQEDLESE-RVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELR 1194
Query: 229 VKKDHVALQVPRGKEDST------LQLLREEN-RALQQLLEQ------------KQAYWA 269
K++ ++ + E+ T +Q LR+ + +AL +L EQ K
Sbjct: 1195 SKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLAL 1254
Query: 270 QAEDTAAPAEESKPAPSPHEEPCSPGLLQDQGSGLSSRFEEPKGPPARQEDSKELRALRK 329
+AE + AE S + E L+ Q + R + G AR E +++L+ +
Sbjct: 1255 EAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGD--GERARAEAAEKLQRAQA 1312
Query: 330 MVSNMSGPSGEEEAKVGPGLPDGCQPLQLLREMRQALQALLKENRLLQEENRTLQVLRAE 389
+ N+SG E E+K ++L +E+ L LLQEE R L +
Sbjct: 1313 ELENVSGALNEAESKT----------IRLSKELSSTEAQLHDAQELLQEETRAKLALGSR 1362
Query: 390 HRGFQEENKALWE 402
R + E L E
Sbjct: 1363 VRAMEAEAAGLRE 1375
Score = 34.7 bits (78), Expect = 0.18
Identities = 66/282 (23%), Positives = 118/282 (41%), Gaps = 48/282 (17%)
Query: 169 QEENKSLREENKALREENRMLSKENKILQVFWEEHKASLGREESRAPSPLLHK--DSASL 226
QE K + ++ RE + + ++ Q+ EE +A L E+ RA + L + ++
Sbjct: 884 QELQKVQELQQQSAREVGEL---QGRVAQL--EEERARLA-EQLRAEAELCAEAEETRGR 937
Query: 227 EVVKKDHVALQVPR-----GKEDSTLQLLREENRALQQLLEQKQAYWAQAEDTAAPAEES 281
+K + L V G+E+ + ++ E + LQQ +++ +A+ E +
Sbjct: 938 LAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLE 997
Query: 282 KPAPSPHEEPCSPG--LLQDQGSGLSSRFEEPKGPPARQEDSKELRALRKMVSNMSGPSG 339
K + LL+DQ S L SKE + L ++ S +
Sbjct: 998 KVTTEAKMKKFEEDLLLLEDQNSKL----------------SKERKLLEDRLAEFSSQAA 1041
Query: 340 EEEAKVGPGLPDGCQPLQLLREMRQALQALLKENRLLQEENRTLQVLRAEHRGFQEENKA 399
EEE KV + L LR +A A +++ L++E + Q L R E+
Sbjct: 1042 EEEEKV--------KSLNKLRLKYEATIADMEDR--LRKEEKGRQELEKLKRRLDGESSE 1091
Query: 400 LWENNKLKLQQKLVIDTVTEVTARMEMLIEELYAFMPARSQD 441
L E ++ QQ+ E+ A++ EEL A + AR++D
Sbjct: 1092 LQE-QMVEQQQR-----AEELRAQLGRKEEELQAAL-ARAED 1126
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 43.5 bits (101), Expect = 4e-04
Identities = 69/284 (24%), Positives = 103/284 (36%), Gaps = 50/284 (17%)
Query: 173 KSLREENKALREENRMLSKENKILQVFWEEHKASLGREESRAPSPLLHKDSASLEVVKKD 232
K E+ L ++N LSKE K+L+ E + EE + S L+K E D
Sbjct: 998 KKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKS--LNKLRLKYEATIAD 1055
Query: 233 HVALQVPRGKEDSTLQLLREENRAL--------QQLLEQKQAYWAQAEDTAAPAEESKPA 284
++ KE+ Q L + R L +Q++EQ+Q AEE +
Sbjct: 1056 ---MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQR-----------AEELRAQ 1101
Query: 285 PSPHEEPCSPGLLQDQGSG------LSSRFEEPKGPPARQEDSKELRALRKMVSNMSGPS 338
EE L + + G L S E QED + R R
Sbjct: 1102 LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDL 1161
Query: 339 GEEEAKVGPGLPDGCQPLQLLREMRQALQALLKE-NRLLQEENR----TLQVLRAEHRGF 393
GEE + L D +E+R + + E + L+EE R +Q LR H
Sbjct: 1162 GEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQA 1221
Query: 394 QEE----------NKALWENNKLKLQQKLVIDTVTEVTARMEML 427
E K WE +L L+ + V+E+ A + L
Sbjct: 1222 LGELAEQLEQARRGKGAWEKTRLALEAE-----VSELRAELSSL 1260
Score = 40.0 bits (92), Expect = 0.004
Identities = 64/253 (25%), Positives = 102/253 (40%), Gaps = 36/253 (14%)
Query: 173 KSLREENKALREENRMLSKENKILQVFWEEHKASLGREESRAPSPL---LHKDSASLEV- 228
KSLRE AL E L E ++ + E+ + LG E L L +A E+
Sbjct: 1128 KSLREAQAALAEAQEDLESE-RVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELR 1186
Query: 229 VKKDHVALQVPRGKEDST------LQLLREEN-RALQQLLEQ------------KQAYWA 269
K++ ++ + E+ T +Q LR+ + +AL +L EQ K
Sbjct: 1187 SKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLAL 1246
Query: 270 QAEDTAAPAEESKPAPSPHEEPCSPGLLQDQGSGLSSRFEEPKGPPARQEDSKELRALRK 329
+AE + AE S + E L+ Q + R + G AR E +++L+ +
Sbjct: 1247 EAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGD--GERARAEAAEKLQRAQA 1304
Query: 330 MVSNMSGPSGEEEAKVGPGLPDGCQPLQLLREMRQALQALLKENRLLQEENRTLQVLRAE 389
+ N+SG E E+K ++L +E+ L LLQEE R L +
Sbjct: 1305 ELENVSGALNEAESKT----------IRLSKELSSTEAQLHDAQELLQEETRAKLALGSR 1354
Query: 390 HRGFQEENKALWE 402
R + E L E
Sbjct: 1355 VRAMEAEAAGLRE 1367
Score = 34.7 bits (78), Expect = 0.18
Identities = 66/282 (23%), Positives = 118/282 (41%), Gaps = 48/282 (17%)
Query: 169 QEENKSLREENKALREENRMLSKENKILQVFWEEHKASLGREESRAPSPLLHK--DSASL 226
QE K + ++ RE + + ++ Q+ EE +A L E+ RA + L + ++
Sbjct: 876 QELQKVQELQQQSAREVGEL---QGRVAQL--EEERARLA-EQLRAEAELCAEAEETRGR 929
Query: 227 EVVKKDHVALQVPR-----GKEDSTLQLLREENRALQQLLEQKQAYWAQAEDTAAPAEES 281
+K + L V G+E+ + ++ E + LQQ +++ +A+ E +
Sbjct: 930 LAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLE 989
Query: 282 KPAPSPHEEPCSPG--LLQDQGSGLSSRFEEPKGPPARQEDSKELRALRKMVSNMSGPSG 339
K + LL+DQ S L SKE + L ++ S +
Sbjct: 990 KVTTEAKMKKFEEDLLLLEDQNSKL----------------SKERKLLEDRLAEFSSQAA 1033
Query: 340 EEEAKVGPGLPDGCQPLQLLREMRQALQALLKENRLLQEENRTLQVLRAEHRGFQEENKA 399
EEE KV + L LR +A A +++ L++E + Q L R E+
Sbjct: 1034 EEEEKV--------KSLNKLRLKYEATIADMEDR--LRKEEKGRQELEKLKRRLDGESSE 1083
Query: 400 LWENNKLKLQQKLVIDTVTEVTARMEMLIEELYAFMPARSQD 441
L E ++ QQ+ E+ A++ EEL A + AR++D
Sbjct: 1084 LQE-QMVEQQQR-----AEELRAQLGRKEEELQAAL-ARAED 1118
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 43.5 bits (101), Expect = 4e-04
Identities = 69/284 (24%), Positives = 103/284 (36%), Gaps = 50/284 (17%)
Query: 173 KSLREENKALREENRMLSKENKILQVFWEEHKASLGREESRAPSPLLHKDSASLEVVKKD 232
K E+ L ++N LSKE K+L+ E + EE + S L+K E D
Sbjct: 1039 KKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKS--LNKLRLKYEATIAD 1096
Query: 233 HVALQVPRGKEDSTLQLLREENRAL--------QQLLEQKQAYWAQAEDTAAPAEESKPA 284
++ KE+ Q L + R L +Q++EQ+Q AEE +
Sbjct: 1097 ---MEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQR-----------AEELRAQ 1142
Query: 285 PSPHEEPCSPGLLQDQGSG------LSSRFEEPKGPPARQEDSKELRALRKMVSNMSGPS 338
EE L + + G L S E QED + R R
Sbjct: 1143 LGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDL 1202
Query: 339 GEEEAKVGPGLPDGCQPLQLLREMRQALQALLKE-NRLLQEENR----TLQVLRAEHRGF 393
GEE + L D +E+R + + E + L+EE R +Q LR H
Sbjct: 1203 GEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQA 1262
Query: 394 QEE----------NKALWENNKLKLQQKLVIDTVTEVTARMEML 427
E K WE +L L+ + V+E+ A + L
Sbjct: 1263 LGELAEQLEQARRGKGAWEKTRLALEAE-----VSELRAELSSL 1301
Score = 40.0 bits (92), Expect = 0.004
Identities = 64/253 (25%), Positives = 102/253 (40%), Gaps = 36/253 (14%)
Query: 173 KSLREENKALREENRMLSKENKILQVFWEEHKASLGREESRAPSPL---LHKDSASLEV- 228
KSLRE AL E L E ++ + E+ + LG E L L +A E+
Sbjct: 1169 KSLREAQAALAEAQEDLESE-RVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELR 1227
Query: 229 VKKDHVALQVPRGKEDST------LQLLREEN-RALQQLLEQ------------KQAYWA 269
K++ ++ + E+ T +Q LR+ + +AL +L EQ K
Sbjct: 1228 SKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLAL 1287
Query: 270 QAEDTAAPAEESKPAPSPHEEPCSPGLLQDQGSGLSSRFEEPKGPPARQEDSKELRALRK 329
+AE + AE S + E L+ Q + R + G AR E +++L+ +
Sbjct: 1288 EAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGD--GERARAEAAEKLQRAQA 1345
Query: 330 MVSNMSGPSGEEEAKVGPGLPDGCQPLQLLREMRQALQALLKENRLLQEENRTLQVLRAE 389
+ N+SG E E+K ++L +E+ L LLQEE R L +
Sbjct: 1346 ELENVSGALNEAESKT----------IRLSKELSSTEAQLHDAQELLQEETRAKLALGSR 1395
Query: 390 HRGFQEENKALWE 402
R + E L E
Sbjct: 1396 VRAMEAEAAGLRE 1408
Score = 34.7 bits (78), Expect = 0.18
Identities = 66/282 (23%), Positives = 118/282 (41%), Gaps = 48/282 (17%)
Query: 169 QEENKSLREENKALREENRMLSKENKILQVFWEEHKASLGREESRAPSPLLHK--DSASL 226
QE K + ++ RE + + ++ Q+ EE +A L E+ RA + L + ++
Sbjct: 917 QELQKVQELQQQSAREVGEL---QGRVAQL--EEERARLA-EQLRAEAELCAEAEETRGR 970
Query: 227 EVVKKDHVALQVPR-----GKEDSTLQLLREENRALQQLLEQKQAYWAQAEDTAAPAEES 281
+K + L V G+E+ + ++ E + LQQ +++ +A+ E +
Sbjct: 971 LAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLE 1030
Query: 282 KPAPSPHEEPCSPG--LLQDQGSGLSSRFEEPKGPPARQEDSKELRALRKMVSNMSGPSG 339
K + LL+DQ S L SKE + L ++ S +
Sbjct: 1031 KVTTEAKMKKFEEDLLLLEDQNSKL----------------SKERKLLEDRLAEFSSQAA 1074
Query: 340 EEEAKVGPGLPDGCQPLQLLREMRQALQALLKENRLLQEENRTLQVLRAEHRGFQEENKA 399
EEE KV + L LR +A A +++ L++E + Q L R E+
Sbjct: 1075 EEEEKV--------KSLNKLRLKYEATIADMEDR--LRKEEKGRQELEKLKRRLDGESSE 1124
Query: 400 LWENNKLKLQQKLVIDTVTEVTARMEMLIEELYAFMPARSQD 441
L E ++ QQ+ E+ A++ EEL A + AR++D
Sbjct: 1125 LQE-QMVEQQQR-----AEELRAQLGRKEEELQAAL-ARAED 1159
>gi|169168460 PREDICTED: chibby homolog 3 (Drosophila) [Homo
sapiens]
Length = 242
Score = 43.1 bits (100), Expect = 5e-04
Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 4/85 (4%)
Query: 91 PLNRFSSVP-LDPMERPMSQADLELDYNPPRVQLSDEMFVFQDGRWVNEN--CRLQSPYF 147
PL R S+ ++ QA+L L Y P ++LS++ FVF+ GRW E+ R +SP
Sbjct: 94 PLRRMPSLSTFYLLDHNTRQAELGLAYGAPCMRLSNQAFVFRGGRWTTESQLARTRSPLL 153
Query: 148 SPSASFHHKLHHKRLAKECMLQEEN 172
S +A + K +R + +L+E N
Sbjct: 154 SRTA-WGWKAQVQRSKSQVLLEENN 177
Score = 37.0 bits (84), Expect = 0.036
Identities = 18/28 (64%), Positives = 22/28 (78%)
Query: 400 LWENNKLKLQQKLVIDTVTEVTARMEML 427
L ENN LKLQQ+L+ID +TE ARM +L
Sbjct: 173 LEENNYLKLQQELLIDMLTETMARMHLL 200
>gi|88990086 PREDICTED: chibby homolog 3 (Drosophila) [Homo sapiens]
Length = 242
Score = 43.1 bits (100), Expect = 5e-04
Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 4/85 (4%)
Query: 91 PLNRFSSVP-LDPMERPMSQADLELDYNPPRVQLSDEMFVFQDGRWVNEN--CRLQSPYF 147
PL R S+ ++ QA+L L Y P ++LS++ FVF+ GRW E+ R +SP
Sbjct: 94 PLRRMPSLSTFYLLDHNTRQAELGLAYGAPCMRLSNQAFVFRGGRWTTESQLARTRSPLL 153
Query: 148 SPSASFHHKLHHKRLAKECMLQEEN 172
S +A + K +R + +L+E N
Sbjct: 154 SRTA-WGWKAQVQRSKSQVLLEENN 177
Score = 37.0 bits (84), Expect = 0.036
Identities = 18/28 (64%), Positives = 22/28 (78%)
Query: 400 LWENNKLKLQQKLVIDTVTEVTARMEML 427
L ENN LKLQQ+L+ID +TE ARM +L
Sbjct: 173 LEENNYLKLQQELLIDMLTETMARMHLL 200
>gi|88986509 PREDICTED: chibby homolog 3 (Drosophila) [Homo sapiens]
Length = 242
Score = 43.1 bits (100), Expect = 5e-04
Identities = 29/85 (34%), Positives = 46/85 (54%), Gaps = 4/85 (4%)
Query: 91 PLNRFSSVP-LDPMERPMSQADLELDYNPPRVQLSDEMFVFQDGRWVNEN--CRLQSPYF 147
PL R S+ ++ QA+L L Y P ++LS++ FVF+ GRW E+ R +SP
Sbjct: 94 PLRRMPSLSTFYLLDHNTRQAELGLAYGAPCMRLSNQAFVFRGGRWTTESQLARTRSPLL 153
Query: 148 SPSASFHHKLHHKRLAKECMLQEEN 172
S +A + K +R + +L+E N
Sbjct: 154 SRTA-WGWKAQVQRSKSQVLLEENN 177
Score = 37.0 bits (84), Expect = 0.036
Identities = 18/28 (64%), Positives = 22/28 (78%)
Query: 400 LWENNKLKLQQKLVIDTVTEVTARMEML 427
L ENN LKLQQ+L+ID +TE ARM +L
Sbjct: 173 LEENNYLKLQQELLIDMLTETMARMHLL 200
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 42.4 bits (98), Expect = 9e-04
Identities = 65/302 (21%), Positives = 123/302 (40%), Gaps = 49/302 (16%)
Query: 154 HHKLHHKRLAKECMLQ-----------EENKSLREENKALR----EENRMLSKENKILQV 198
H +HH+ L E L +E + L+++ + L+ +E ++L ++ ++ Q
Sbjct: 138 HQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQ 197
Query: 199 FWEEHKASLGREESRAPSPLLHKDSASLEVVKKDHVALQVPRGKEDSTLQLLREENRALQ 258
E+ +E+ + L ++ + ++ LQ + L LL+++ + Q
Sbjct: 198 VQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQ-----QQQQLLLLQQQGQLQQ 252
Query: 259 QLLEQKQAYWAQ--AEDTAAPAEESKPAPSPH--EEPCSPGLLQDQGSGLSSRFEEPKGP 314
QLL+Q+QA Q E A ++ ++ LLQ Q L + +P P
Sbjct: 253 QLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQP--P 310
Query: 315 PARQEDSKELRALRKMVSNMSGPSGEEEAKVGPGLPDGCQPLQLLREMRQALQALLKENR 374
P E+ +E+ + M G E Q L + RQ L+ + R
Sbjct: 311 PLEPEEEEEVE-----LELMPVDLGSE---------------QELEQQRQELERQQELER 350
Query: 375 LLQEENRTLQVLRAEHRGFQEENKALWENNKLKLQQKLVIDTVTEVTARMEMLIEELYAF 434
Q+E R LQ L+ + Q E + + +L+ Q+ + T E+ A+ + + EL
Sbjct: 351 --QQEQRQLQ-LKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPV 407
Query: 435 MP 436
P
Sbjct: 408 QP 409
Score = 33.1 bits (74), Expect = 0.52
Identities = 39/173 (22%), Positives = 70/173 (40%), Gaps = 15/173 (8%)
Query: 250 LREENRALQQLLEQKQAYWAQAEDTAAPAEESKPAPSPHEEPCSPGLLQDQGSGLSSRFE 309
+ EE R Q+ L+ +Q Q E P E P PH E Q G S+ +
Sbjct: 78 IAEETRPGQRELQLQQLE-QQPEPQQQPQHEQLQQPQPHLELQQQP--QQDGQQQLSQLQ 134
Query: 310 EPKGPPARQEDSKELRALRKMVSNMSGPSGEEEAKVGPGLPD----GCQPLQLLREMRQA 365
+ K ++ K L + +E+ ++ Q Q+L++ Q
Sbjct: 135 QEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQ- 193
Query: 366 LQALLKENRLLQEENRTLQVLRA-------EHRGFQEENKALWENNKLKLQQK 411
LQ ++E +LLQ++ LQ + + + FQ++ + L + +L L Q+
Sbjct: 194 LQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQ 246
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 42.4 bits (98), Expect = 9e-04
Identities = 63/260 (24%), Positives = 112/260 (43%), Gaps = 40/260 (15%)
Query: 146 YFSPSASFHHKLHHKRLAKECMLQEENKSLREENKALREENRMLSKENKILQVFWEEHKA 205
Y A + L KE M +E +SL++E +AL+E L+ + +IL+ EE +
Sbjct: 159 YMEEMADTADAIEMATLDKE-MAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGS 217
Query: 206 S----------LGREESRAPSPLLH-KDSASLEVVKKDHVALQVPRGKEDSTLQLLREEN 254
L + +R L+ +D +S E K++HV LQ K++ L+++R++
Sbjct: 218 DGAASSYQLKQLEEQNARLKDALVRMRDLSSSE--KQEHVKLQKLMEKKNQELEVVRQQR 275
Query: 255 RALQQLLEQKQAYWAQAEDTAAPAEESKPAPSPHEEPCSPGLLQDQGSGLSSRFEEPKGP 314
LQ+ L +QAE T +E A EE +L D+ L + E
Sbjct: 276 ERLQEEL-------SQAESTIDELKEQVDAALGAEEMVE--MLTDRNLNLEEKVRE---- 322
Query: 315 PARQEDSKELRALRKMVSNMSGPSGEEEAKV-------GPGLPDGCQPLQLLREMRQALQ 367
+E +L A+ +M + + E E ++ G + + + ++ +E Q
Sbjct: 323 --LRETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQ 380
Query: 368 ALLKENRL----LQEENRTL 383
+K+ R LQ+ NR L
Sbjct: 381 QTIKKYRQLTAHLQDVNREL 400
Score = 37.0 bits (84), Expect = 0.036
Identities = 65/275 (23%), Positives = 115/275 (41%), Gaps = 44/275 (16%)
Query: 177 EENKALREENRMLSKENKILQVFWEEHKASLGREESRAPSPLLHKDSASLEVVKKDHVAL 236
+E + LR + R L ++ + L+ L R E +A L K LE V++ +
Sbjct: 81 KEEEGLRAQVRDLEEKLETLR---------LKRAEDKAKLKELEKHKIQLEQVQEWKSKM 131
Query: 237 QVPRGKEDSTLQL-LREENRALQQLLEQKQAYWAQAEDTAAPAEESKPAPSPHEEPCSPG 295
Q ++ + LQ L+E + ++ LE K+ Y + DTA E + EE
Sbjct: 132 Q----EQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAES- 186
Query: 296 LLQDQGSGLSSRFE-------------EPKGPPAR---------QEDSKELRALRKMVSN 333
LQ + L R + E KG +E + L+ + +
Sbjct: 187 -LQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRD 245
Query: 334 MSGPSGEEEAKVGPGLPDGCQPLQLLREMRQALQALLKENRLLQEENRTLQVLRAEHRGF 393
+S +E K+ + Q L+++R+ R+ LQ L + +E + QV A G
Sbjct: 246 LSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKE-QVDAA--LGA 302
Query: 394 QEENKALWENNKLKLQQKL--VIDTVTEVTARMEM 426
+E + L + N L L++K+ + +TV ++ A EM
Sbjct: 303 EEMVEMLTDRN-LNLEEKVRELRETVGDLEAMNEM 336
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 42.4 bits (98), Expect = 9e-04
Identities = 63/260 (24%), Positives = 112/260 (43%), Gaps = 40/260 (15%)
Query: 146 YFSPSASFHHKLHHKRLAKECMLQEENKSLREENKALREENRMLSKENKILQVFWEEHKA 205
Y A + L KE M +E +SL++E +AL+E L+ + +IL+ EE +
Sbjct: 273 YMEEMADTADAIEMATLDKE-MAEERAESLQQEVEALKERVDELTTDLEILKAEIEEKGS 331
Query: 206 S----------LGREESRAPSPLLH-KDSASLEVVKKDHVALQVPRGKEDSTLQLLREEN 254
L + +R L+ +D +S E K++HV LQ K++ L+++R++
Sbjct: 332 DGAASSYQLKQLEEQNARLKDALVRMRDLSSSE--KQEHVKLQKLMEKKNQELEVVRQQR 389
Query: 255 RALQQLLEQKQAYWAQAEDTAAPAEESKPAPSPHEEPCSPGLLQDQGSGLSSRFEEPKGP 314
LQ+ L +QAE T +E A EE +L D+ L + E
Sbjct: 390 ERLQEEL-------SQAESTIDELKEQVDAALGAEEMVE--MLTDRNLNLEEKVRE---- 436
Query: 315 PARQEDSKELRALRKMVSNMSGPSGEEEAKV-------GPGLPDGCQPLQLLREMRQALQ 367
+E +L A+ +M + + E E ++ G + + + ++ +E Q
Sbjct: 437 --LRETVGDLEAMNEMNDELQENARETELELREQLDMAGARVREAQKRVEAAQETVADYQ 494
Query: 368 ALLKENRL----LQEENRTL 383
+K+ R LQ+ NR L
Sbjct: 495 QTIKKYRQLTAHLQDVNREL 514
Score = 37.0 bits (84), Expect = 0.036
Identities = 65/275 (23%), Positives = 115/275 (41%), Gaps = 44/275 (16%)
Query: 177 EENKALREENRMLSKENKILQVFWEEHKASLGREESRAPSPLLHKDSASLEVVKKDHVAL 236
+E + LR + R L ++ + L+ L R E +A L K LE V++ +
Sbjct: 195 KEEEGLRAQVRDLEEKLETLR---------LKRAEDKAKLKELEKHKIQLEQVQEWKSKM 245
Query: 237 QVPRGKEDSTLQL-LREENRALQQLLEQKQAYWAQAEDTAAPAEESKPAPSPHEEPCSPG 295
Q ++ + LQ L+E + ++ LE K+ Y + DTA E + EE
Sbjct: 246 Q----EQQADLQRRLKEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAES- 300
Query: 296 LLQDQGSGLSSRFE-------------EPKGPPAR---------QEDSKELRALRKMVSN 333
LQ + L R + E KG +E + L+ + +
Sbjct: 301 -LQQEVEALKERVDELTTDLEILKAEIEEKGSDGAASSYQLKQLEEQNARLKDALVRMRD 359
Query: 334 MSGPSGEEEAKVGPGLPDGCQPLQLLREMRQALQALLKENRLLQEENRTLQVLRAEHRGF 393
+S +E K+ + Q L+++R+ R+ LQ L + +E + QV A G
Sbjct: 360 LSSSEKQEHVKLQKLMEKKNQELEVVRQQRERLQEELSQAESTIDELKE-QVDAA--LGA 416
Query: 394 QEENKALWENNKLKLQQKL--VIDTVTEVTARMEM 426
+E + L + N L L++K+ + +TV ++ A EM
Sbjct: 417 EEMVEMLTDRN-LNLEEKVRELRETVGDLEAMNEM 450
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,385,613
Number of Sequences: 37866
Number of extensions: 1007708
Number of successful extensions: 6021
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 76
Number of HSP's successfully gapped in prelim test: 429
Number of HSP's that attempted gapping in prelim test: 4961
Number of HSP's gapped (non-prelim): 1309
length of query: 448
length of database: 18,247,518
effective HSP length: 106
effective length of query: 342
effective length of database: 14,233,722
effective search space: 4867932924
effective search space used: 4867932924
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.