Guide to the Human Genome
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Search of human proteins with 226529650

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226529650 adenosine deaminase domain containing 1
(testis-specific) isoform 2 [Homo sapiens]
         (565 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226529650 adenosine deaminase domain containing 1 (testis-spe...  1123   0.0  
gi|21245124 adenosine deaminase domain containing 1 (testis-spec...  1115   0.0  
gi|226530771 adenosine deaminase domain containing 1 (testis-spe...  1077   0.0  
gi|223972690 adenosine deaminase domain containing 2 isoform 2 [...   169   6e-42
gi|223972688 adenosine deaminase domain containing 2 isoform 1 [...   167   2e-41
gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo s...   145   1e-34
gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens]       143   4e-34
gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo s...   132   8e-31
gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo...   132   1e-30
gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo sa...   128   2e-29
gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo sa...   126   5e-29
gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo sa...   126   5e-29
gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo sa...   122   1e-27
gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo s...   119   7e-27
gi|6912230 adenosine deaminase, tRNA-specific 1 [Homo sapiens]         55   1e-07
gi|208431829 eukaryotic translation initiation factor 2-alpha ki...    42   0.002
gi|208431827 eukaryotic translation initiation factor 2-alpha ki...    42   0.002
gi|4506103 eukaryotic translation initiation factor 2-alpha kina...    42   0.002
gi|7657625 staufen homolog 2 [Homo sapiens]                            40   0.004
gi|57529737 PDZ domain containing ring finger 3 [Homo sapiens]         36   0.11 
gi|82659089 staufen isoform a [Homo sapiens]                           35   0.14 
gi|82659087 staufen isoform b [Homo sapiens]                           35   0.14 
gi|82659085 staufen isoform a [Homo sapiens]                           35   0.14 
gi|82659083 staufen isoform a [Homo sapiens]                           35   0.14 
gi|82659091 staufen isoform c [Homo sapiens]                           33   0.70 
gi|24234756 interleukin enhancer binding factor 3 isoform c [Hom...    32   1.6  
gi|24234753 interleukin enhancer binding factor 3 isoform b [Hom...    32   1.6  
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom...    32   1.6  
gi|27545313 ubiquitin specific peptidase 38 [Homo sapiens]             32   1.6  
gi|189409142 telomeric repeat binding factor 1 isoform 1 [Homo s...    32   2.0  

>gi|226529650 adenosine deaminase domain containing 1
           (testis-specific) isoform 2 [Homo sapiens]
          Length = 565

 Score = 1124 bits (2906), Expect = 0.0
 Identities = 565/565 (100%), Positives = 565/565 (100%)

Query: 1   MASNNHWFQSSQVPSFAQMLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNF 60
           MASNNHWFQSSQVPSFAQMLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNF
Sbjct: 1   MASNNHWFQSSQVPSFAQMLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNF 60

Query: 61  PEPLLSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTT 120
           PEPLLSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTT
Sbjct: 61  PEPLLSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTT 120

Query: 121 GNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPP 180
           GNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPP
Sbjct: 121 GNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPP 180

Query: 181 FPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIE 240
           FPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIE
Sbjct: 181 FPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIE 240

Query: 241 RAGQHEVVAIGTGEYNYSQDIKPDGRVLHDTHAVVTARRSLLSKNPAMMEKSIFCTEPTS 300
           RAGQHEVVAIGTGEYNYSQDIKPDGRVLHDTHAVVTARRSLLSKNPAMMEKSIFCTEPTS
Sbjct: 241 RAGQHEVVAIGTGEYNYSQDIKPDGRVLHDTHAVVTARRSLLSKNPAMMEKSIFCTEPTS 300

Query: 301 NLLTLKQNINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVY 360
           NLLTLKQNINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVY
Sbjct: 301 NLLTLKQNINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVY 360

Query: 361 CPKDGVNRISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAI 420
           CPKDGVNRISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAI
Sbjct: 361 CPKDGVNRISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAI 420

Query: 421 KQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSG 480
           KQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSG
Sbjct: 421 KQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSG 480

Query: 481 KITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCK 540
           KITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCK
Sbjct: 481 KITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCK 540

Query: 541 LKSYLQQHGYGSWIVKSPCIEQFNM 565
           LKSYLQQHGYGSWIVKSPCIEQFNM
Sbjct: 541 LKSYLQQHGYGSWIVKSPCIEQFNM 565


>gi|21245124 adenosine deaminase domain containing 1
           (testis-specific) isoform 1 [Homo sapiens]
          Length = 576

 Score = 1115 bits (2884), Expect = 0.0
 Identities = 565/576 (98%), Positives = 565/576 (98%), Gaps = 11/576 (1%)

Query: 1   MASNNHWFQSSQVPSFAQMLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNF 60
           MASNNHWFQSSQVPSFAQMLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNF
Sbjct: 1   MASNNHWFQSSQVPSFAQMLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNF 60

Query: 61  PEPLLSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTT 120
           PEPLLSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTT
Sbjct: 61  PEPLLSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTT 120

Query: 121 GNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPP 180
           GNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPP
Sbjct: 121 GNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPP 180

Query: 181 FPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIE 240
           FPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIE
Sbjct: 181 FPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIE 240

Query: 241 RAGQHEVVAIGTGEYNYSQDIKPDGRVLHDTHAVVTARRSLL-----------SKNPAMM 289
           RAGQHEVVAIGTGEYNYSQDIKPDGRVLHDTHAVVTARRSLL           SKNPAMM
Sbjct: 241 RAGQHEVVAIGTGEYNYSQDIKPDGRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMM 300

Query: 290 EKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHV 349
           EKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHV
Sbjct: 301 EKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHV 360

Query: 350 AVEGKIYLTVYCPKDGVNRISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGN 409
           AVEGKIYLTVYCPKDGVNRISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGN
Sbjct: 361 AVEGKIYLTVYCPKDGVNRISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGN 420

Query: 410 CSDTRGLEIAIKQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD 469
           CSDTRGLEIAIKQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD
Sbjct: 421 CSDTRGLEIAIKQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD 480

Query: 470 VSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKC 529
           VSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKC
Sbjct: 481 VSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKC 540

Query: 530 MSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQFNM 565
           MSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQFNM
Sbjct: 541 MSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQFNM 576


>gi|226530771 adenosine deaminase domain containing 1
           (testis-specific) isoform 3 [Homo sapiens]
          Length = 558

 Score = 1077 bits (2786), Expect = 0.0
 Identities = 547/558 (98%), Positives = 547/558 (98%), Gaps = 11/558 (1%)

Query: 19  MLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNFPEPLLSKNLSSISNPVLP 78
           MLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNFPEPLLSKNLSSISNPVLP
Sbjct: 1   MLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNFPEPLLSKNLSSISNPVLP 60

Query: 79  PKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQ 138
           PKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQ
Sbjct: 61  PKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQ 120

Query: 139 YKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYVSKVH 198
           YKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYVSKVH
Sbjct: 121 YKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYVSKVH 180

Query: 199 YEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQHEVVAIGTGEYNYS 258
           YEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQHEVVAIGTGEYNYS
Sbjct: 181 YEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQHEVVAIGTGEYNYS 240

Query: 259 QDIKPDGRVLHDTHAVVTARRSLL-----------SKNPAMMEKSIFCTEPTSNLLTLKQ 307
           QDIKPDGRVLHDTHAVVTARRSLL           SKNPAMMEKSIFCTEPTSNLLTLKQ
Sbjct: 241 QDIKPDGRVLHDTHAVVTARRSLLRYFYRQLLLFYSKNPAMMEKSIFCTEPTSNLLTLKQ 300

Query: 308 NINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVYCPKDGVN 367
           NINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVYCPKDGVN
Sbjct: 301 NINICLYMNQLPKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVYCPKDGVN 360

Query: 368 RISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQRVDDA 427
           RISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQRVDDA
Sbjct: 361 RISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQRVDDA 420

Query: 428 LTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSGKITESSP 487
           LTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSGKITESSP
Sbjct: 421 LTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSGKITESSP 480

Query: 488 FKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQ 547
           FKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQ
Sbjct: 481 FKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQ 540

Query: 548 HGYGSWIVKSPCIEQFNM 565
           HGYGSWIVKSPCIEQFNM
Sbjct: 541 HGYGSWIVKSPCIEQFNM 558


>gi|223972690 adenosine deaminase domain containing 2 isoform 2
           [Homo sapiens]
          Length = 583

 Score =  169 bits (428), Expect = 6e-42
 Identities = 149/468 (31%), Positives = 228/468 (48%), Gaps = 55/468 (11%)

Query: 125 GPYFAFC--AVVDGIQYKTGLGQNKKESRSNAAKLALDELL-QLDEPEPRILETSGPPPF 181
           GP F F   A +DG+    G   +K E++  AA  AL  +  QL+ PE    +TS  PP 
Sbjct: 140 GPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESP--QTSSRPP- 196

Query: 182 PAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIER 241
                 L+ L+  + + +E R       + +V   F+ L+  RS Y     ++A  I+ER
Sbjct: 197 ------LAPLSVENILTHEQR------CAALVSAGFDLLLDERSPYWACKGTVAGVILER 244

Query: 242 ----AGQH-----EVVAIGTGEYNYSQDIKPDGRVLHDTHAVVTARRSLL---------- 282
               A  H     ++VA+GTG    +  ++  G+ LHD H +V ARR+LL          
Sbjct: 245 EIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHDCHGLVIARRALLRFLFRQLLLA 304

Query: 283 -SKNPAMMEKSIFCTEPTSNL-LTLKQNINICLYMNQLPKGSAQIKSQLRLNPHSISAFE 340
               P   E+S+   +P      TLK  + + LY++  PKG+A+    + L P S     
Sbjct: 305 TQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAAR---DIYLPPTSEGGLP 361

Query: 341 ANEELCLHVAVEGKIYLTVY-CPKDGVNRISSMSSSDKLTRWEVLGVQGALLSHFIQPVY 399
            +  + L   V G++    Y  P      +  +S+SDKL RW VLG+ GALL+H + P+Y
Sbjct: 362 HSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASDKLARWAVLGLGGALLAHLVSPLY 421

Query: 400 ISSILIGDGNCSDTRGLEIAIKQR--VDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLE 457
            +S+++ D +C D   L  AI  R  +D  L   LP  Y+    H+   P   P +   +
Sbjct: 422 STSLILAD-SCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTPD 480

Query: 458 -YKFLSLNWAQGDVSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKE-AK 515
             + LSLNW+ GD  +E+VD  +G++  +    + +   SRLCKA+ L  F+  A+   K
Sbjct: 481 TCRGLSLNWSLGDPGIEVVDVATGRVKAN----AALGPPSRLCKASFLRAFHQAARAVGK 536

Query: 516 KELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQF 563
             LL   TY AAK  +  YQEA+ +L   L Q G G+W  K P + +F
Sbjct: 537 PYLLALKTYEAAK--AGPYQEARRQLSLLLDQQGLGAWPSK-PLVGKF 581


>gi|223972688 adenosine deaminase domain containing 2 isoform 1
           [Homo sapiens]
          Length = 665

 Score =  167 bits (423), Expect = 2e-41
 Identities = 147/490 (30%), Positives = 232/490 (47%), Gaps = 65/490 (13%)

Query: 113 DLKETVTTGNVMGPYFAFC--AVVDGIQYKTGLGQNKKESRSNAAKLALDELL-QLDEPE 169
           +++  +     +GP F F   A +DG+    G   +K E++  AA  AL  +  QL+ PE
Sbjct: 200 EMESRIPAVEELGPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPE 259

Query: 170 PRILETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLK 229
               +TS  PP       L+ L+  + + +E R       + +V   F+ L+  RS Y  
Sbjct: 260 SP--QTSSRPP-------LAPLSVENILTHEQR------CAALVSAGFDLLLDERSPYWA 304

Query: 230 YSSSLAAFIIERAGQ-------------------HEVVAIGTGEYNYSQDIKPDGRVLHD 270
              ++A  I+ER                      +++VA+GTG    +  ++  G+ LHD
Sbjct: 305 CKGTVAGVILERGWAVSAPSCTEIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHD 364

Query: 271 THAVVTARRSLL-----------SKNPAMMEKSIFCTEPTSNL-LTLKQNINICLYMNQL 318
            H +V ARR+LL              P   E+S+   +P      TLK  + + LY++  
Sbjct: 365 CHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNT 424

Query: 319 PKGSAQIKSQLRLNPHSISAFEANEELCLHVAVEGKIYLTVY-CPKDGVNRISSMSSSDK 377
           PKG+A+    + L P S      +  + L   V G++    Y  P      +  +S+SDK
Sbjct: 425 PKGAAR---DIYLPPTSEGGLPHSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASDK 481

Query: 378 LTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQR--VDDALTSKLPMF 435
           L RW VLG+ GALL+H + P+Y +S+++ D +C D   L  AI  R  +D  L   LP  
Sbjct: 482 LARWAVLGLGGALLAHLVSPLYSTSLILAD-SCHDPPTLSRAIHTRPCLDSVLGPCLPPP 540

Query: 436 YLVNRPHISLVPSAYPLQMNLE-YKFLSLNWAQGDVSLEIVDGLSGKITESSPFKSGMSM 494
           Y+    H+   P   P +   +  + LSLNW+ GD  +E+VD  +G++  +    + +  
Sbjct: 541 YVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKAN----AALGP 596

Query: 495 ASRLCKAAMLSRFNLLAKE-AKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSW 553
            SRLCKA+ L  F+  A+   K  LL   TY AAK  +  YQEA+ +L   L Q G G+W
Sbjct: 597 PSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAK--AGPYQEARRQLSLLLDQQGLGAW 654

Query: 554 IVKSPCIEQF 563
             K P + +F
Sbjct: 655 PSK-PLVGKF 663


>gi|4501919 RNA-specific adenosine deaminase B1 isoform 1 [Homo
           sapiens]
          Length = 701

 Score =  145 bits (365), Expect = 1e-34
 Identities = 151/526 (28%), Positives = 238/526 (45%), Gaps = 84/526 (15%)

Query: 75  PVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVV 134
           PVLPP   P         G+ NPV  L++     R  L       +G      F    VV
Sbjct: 223 PVLPPFPPPS--------GK-NPVMILNEL----RPGLKYDFLSESGESHAKSFVMSVVV 269

Query: 135 DGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYV 194
           DG Q+  G G+NKK +++ AA+ AL  +  L      + +T    P P+E + L    ++
Sbjct: 270 DG-QFFEGSGRNKKLAKARAAQSALAAIFNL-----HLDQTPSRQPIPSEGLQL----HL 319

Query: 195 SKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQ---HEVVAIG 251
            +V  +        +S++V  +F  L  N S        LA  ++         +V+++ 
Sbjct: 320 PQVLADA-------VSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVS 372

Query: 252 TGEYNYSQDIKPD-GRVLHDTHAVVTARRSLLS----------KNPAMMEKSIFCTEPTS 300
           TG    + +   D G  L+D HA + +RRSLL            N    ++SIF      
Sbjct: 373 TGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERG 432

Query: 301 NLLTLKQNINICLYMNQLPKGSAQIKSQLRLNPHSISAFE---------ANEELCLHV-A 350
               LK+N+   LY++  P G A+I S     PH     E         A  +L   + +
Sbjct: 433 GF-RLKENVQFHLYISTSPCGDARIFS-----PHEPILEEPADRHPNRKARGQLRTKIES 486

Query: 351 VEGKIYLTVYCPK---DGV---NRISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSIL 404
            EG I +         DGV    R+ +MS SDK+ RW V+G+QG+LLS F++P+Y SSI+
Sbjct: 487 GEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSII 546

Query: 405 IGDGNCSDTRGLEIAIKQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLN 464
           +G     D   L  A+ QR+ +     LP  Y +N+P +S + +A   Q      F S+N
Sbjct: 547 LGSLYHGD--HLSRAMYQRISN--IEDLPPLYTLNKPLLSGISNAEARQPGKAPNF-SVN 601

Query: 465 WAQGDVSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEA--- 521
           W  GD ++E+++  +G        K  +  ASRLCK A+  R+  +  +    LL +   
Sbjct: 602 WTVGDSAIEVINATTG--------KDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKIT 653

Query: 522 --GTYHAAKCMSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQFNM 565
               YH +K  +  YQ AK +L +   + G G+W+ K    +QF++
Sbjct: 654 KPNVYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQFSL 699


>gi|8922077 adenosine deaminase, RNA-specific, B2 [Homo sapiens]
          Length = 739

 Score =  143 bits (361), Expect = 4e-34
 Identities = 137/470 (29%), Positives = 214/470 (45%), Gaps = 74/470 (15%)

Query: 128 FAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVV 187
           F     VDG  ++ G G++KK +R  AA+ AL EL  +  P        G  P  A    
Sbjct: 306 FVMAVSVDGRTFE-GSGRSKKLARGQAAQAALQELFDIQMP--------GHAPGRARRTP 356

Query: 188 LSELAYVSKVHYEGRHIQYA-KISQIVKERFNQLISNRSEYLKYSSSLAAFIIER---AG 243
           + +              ++A  ISQ+V ++F ++ ++ +       +LA  ++ +   A 
Sbjct: 357 MPQ--------------EFADSISQLVTQKFREVTTDLTPMHARHKALAGIVMTKGLDAR 402

Query: 244 QHEVVAIGTGEYNYS-QDIKPDGRVLHDTHAVVTARRSLL-----------SKNPAMMEK 291
           Q +VVA+ +G    S + +   G V++D HA V ARR+ L           SK     E+
Sbjct: 403 QAQVVALSSGTKCISGEHLSDQGLVVNDCHAEVVARRAFLHFLYTQLELHLSKRREDSER 462

Query: 292 SIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQIKS------QLRLNPHSISAFEANEEL 345
           SIF          L++NI   LY++  P G A++ S       L  + H +  F  +   
Sbjct: 463 SIFVRLKEGGY-RLRENILFHLYVSTSPCGDARLHSPYEITTDLHSSKHLVRKFRGHLRT 521

Query: 346 CLH-----VAVEGKIYLTVYCPKDGV---NRISSMSSSDKLTRWEVLGVQGALLSHFIQP 397
            +      V V G   +  +   DGV    ++ +MS +DK+ RW VLG+QGALLSHF++P
Sbjct: 522 KIESGEGTVPVRGPSAVQTW---DGVLLGEQLITMSCTDKIARWNVLGLQGALLSHFVEP 578

Query: 398 VYISSILIGDGNCSDTRGLEIAIKQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLE 457
           VY+ SI++  G+   T  L   +  R++     +LP  Y  NRP +S V  A   Q    
Sbjct: 579 VYLQSIVV--GSLHHTGHLARVMSHRMEG--VGQLPASYRHNRPLLSGVSDAEARQPGKS 634

Query: 458 YKFLSLNWAQGDVSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKE 517
             F S+NW  G   LEI++  +G+ +   P        SRLCK  + +R+  L       
Sbjct: 635 PPF-SMNWVVGSADLEIINATTGRRSCGGP--------SRLCKHVLSARWARLYGRLSTR 685

Query: 518 LLEAG----TYHAAKCMSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQF 563
               G     Y  AK  + +YQ  K +L    Q+ G G+W+ K P  +QF
Sbjct: 686 TPSPGDTPSMYCEAKLGAHTYQSVKQQLFKAFQKAGLGTWVRKPPEQQQF 735



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 2/95 (2%)

Query: 85  EFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLG 144
           + + K     + P +AL Q  ++ R  L  +    TG V  P FA    V+G+ ++ G G
Sbjct: 114 QLVWKKLSWSVAPKNALVQLHEL-RPGLQYRTVSQTGPVHAPVFAVAVEVNGLTFE-GTG 171

Query: 145 QNKKESRSNAAKLALDELLQLDEPEPRILETSGPP 179
             KK+++  AA+LAL   +Q        L   G P
Sbjct: 172 PTKKKAKMRAAELALRSFVQFPNACQAHLAMGGGP 206


>gi|7669477 RNA-specific adenosine deaminase B1 isoform 2 [Homo
           sapiens]
          Length = 741

 Score =  132 bits (332), Expect = 8e-31
 Identities = 149/561 (26%), Positives = 236/561 (42%), Gaps = 114/561 (20%)

Query: 75  PVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVV 134
           PVLPP   P         G+ NPV  L++     R  L       +G      F    VV
Sbjct: 223 PVLPPFPPPS--------GK-NPVMILNEL----RPGLKYDFLSESGESHAKSFVMSVVV 269

Query: 135 DGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYV 194
           DG Q+  G G+NKK +++ AA+ AL  +  L      + +T    P P+E + L    ++
Sbjct: 270 DG-QFFEGSGRNKKLAKARAAQSALAAIFNL-----HLDQTPSRQPIPSEGLQL----HL 319

Query: 195 SKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQ---HEVVAIG 251
            +V  +        +S++V  +F  L  N S        LA  ++         +V+++ 
Sbjct: 320 PQVLADA-------VSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVS 372

Query: 252 TGEYNYSQDIKPD-GRVLHDTHAVVTARRSLLS----------KNPAMMEKSIFCTEPTS 300
           TG    + +   D G  L+D HA + +RRSLL            N    ++SIF      
Sbjct: 373 TGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERG 432

Query: 301 NLLTLKQNINICLYMNQLP-----------------------------KGSAQIKSQLRL 331
               LK+N+   LY++  P                              GS Q +    L
Sbjct: 433 GF-RLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNHGSLQPRPPGLL 491

Query: 332 NPHSISAFEA---NEELCLHVAVEGKIYLTVYCPK----------------DGV---NRI 369
           +  S S F+     E    H   + +  L                      DGV    R+
Sbjct: 492 SDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERL 551

Query: 370 SSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQRVDDALT 429
            +MS SDK+ RW V+G+QG+LLS F++P+Y SSI++G     D   L  A+ QR+ +   
Sbjct: 552 LTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGD--HLSRAMYQRISN--I 607

Query: 430 SKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSGKITESSPFK 489
             LP  Y +N+P +S + +A   Q      F S+NW  GD ++E+++  +G        K
Sbjct: 608 EDLPPLYTLNKPLLSGISNAEARQPGKAPNF-SVNWTVGDSAIEVINATTG--------K 658

Query: 490 SGMSMASRLCKAAMLSRFNLLAKEAKKELLEA-----GTYHAAKCMSASYQEAKCKLKSY 544
             +  ASRLCK A+  R+  +  +    LL +       YH +K  +  YQ AK +L + 
Sbjct: 659 DELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAKARLFTA 718

Query: 545 LQQHGYGSWIVKSPCIEQFNM 565
             + G G+W+ K    +QF++
Sbjct: 719 FIKAGLGAWVEKPTEQDQFSL 739


>gi|237681091 RNA-specific adenosine deaminase B1 isoform 7 [Homo
           sapiens]
          Length = 674

 Score =  132 bits (331), Expect = 1e-30
 Identities = 144/499 (28%), Positives = 223/499 (44%), Gaps = 84/499 (16%)

Query: 75  PVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVV 134
           PVLPP   P         G+ NPV  L++     R  L       +G      F    VV
Sbjct: 223 PVLPPFPPPS--------GK-NPVMILNEL----RPGLKYDFLSESGESHAKSFVMSVVV 269

Query: 135 DGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYV 194
           DG Q+  G G+NKK +++ AA+ AL  +  L      + +T    P P+E + L    ++
Sbjct: 270 DG-QFFEGSGRNKKLAKARAAQSALAAIFNL-----HLDQTPSRQPIPSEGLQL----HL 319

Query: 195 SKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQ---HEVVAIG 251
            +V  +        +S++V  +F  L  N S        LA  ++         +V+++ 
Sbjct: 320 PQVLADA-------VSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVS 372

Query: 252 TGEYNYSQDIKPD-GRVLHDTHAVVTARRSLLS----------KNPAMMEKSIFCTEPTS 300
           TG    + +   D G  L+D HA + +RRSLL            N    ++SIF      
Sbjct: 373 TGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERG 432

Query: 301 NLLTLKQNINICLYMNQLPKGSAQIKSQLRLNPHSISAFE---------ANEELCLHV-A 350
               LK+N+   LY++  P G A+I S     PH     E         A  +L   + +
Sbjct: 433 GF-RLKENVQFHLYISTSPCGDARIFS-----PHEPILEEPADRHPNRKARGQLRTKIES 486

Query: 351 VEGKIYLTVYCPK---DGV---NRISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSIL 404
            EG I +         DGV    R+ +MS SDK+ RW V+G+QG+LLS F++P+Y SSI+
Sbjct: 487 GEGTIPVRSNASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSII 546

Query: 405 IGDGNCSDTRGLEIAIKQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLN 464
           +G     D   L  A+ QR+ +     LP  Y +N+P +S + +A   Q      F S+N
Sbjct: 547 LGSLYHGD--HLSRAMYQRISN--IEDLPPLYTLNKPLLSGISNAEARQPGKAPNF-SVN 601

Query: 465 WAQGDVSLEIVDGLSGKITESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEA--- 521
           W  GD ++E+++  +G        K  +  ASRLCK A+  R+  +  +    LL +   
Sbjct: 602 WTVGDSAIEVINATTG--------KDELGRASRLCKHALYCRWMRVHGKVPSHLLRSKIT 653

Query: 522 --GTYHAAKCMSASYQEAK 538
               YH +K  +  YQ AK
Sbjct: 654 KPNVYHESKLAAKEYQAAK 672


>gi|70166944 adenosine deaminase, RNA-specific isoform b [Homo
            sapiens]
          Length = 1200

 Score =  128 bits (321), Expect = 2e-29
 Identities = 138/536 (25%), Positives = 231/536 (43%), Gaps = 67/536 (12%)

Query: 54   TQVTGNFPEPLLSKNLSSISNPVLPPKKIPK-EFIMKYKRGEINPVSALHQFAQMQRVQL 112
            +  + N PE ++S++L ++ +  + P K+ K   +++Y     NPV  L ++A+      
Sbjct: 687  SMASDNQPEGMISESLDNLES--MMPNKVRKIGELVRYLN--TNPVGGLLEYARSHGFAA 742

Query: 113  DLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 172
            + K    +G    P F + A V G  +      +KK+ +  AA  AL  L+  +E     
Sbjct: 743  EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEK---- 798

Query: 173  LETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSS 232
                      AE +  +EL       ++       +I+ +    FN L ++    L    
Sbjct: 799  ----------AERMGFTELPLTGSTFHD-------QIAMLSHRCFNTLTNSFQPSLLGRK 841

Query: 233  SLAAFIIERAGQHE--VVAIGTGEYNYSQD-IKPDGRVLHDTHAVVTARRS--------L 281
             LAA I+++  +    VV++GTG      D +   G  ++D HA + +RR         L
Sbjct: 842  ILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIRFLYSEL 901

Query: 282  LSKNPAMMEKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQI-------KSQLRLNPH 334
            +  N    + SIF        L +K+ ++  LY++  P G   +       ++       
Sbjct: 902  MKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAMESTESR 961

Query: 335  SISAFEANEELCLHVAVE---GKIYLT---VYCPKDGVN---RISSMSSSDKLTRWEVLG 385
                FE  ++  L   VE   G I +    +    DG+    R+ +MS SDK+ RW VLG
Sbjct: 962  HYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKILRWNVLG 1021

Query: 386  VQGALLSHFIQPVYISSILIG----DGNCSDTRGLEIAIKQRVDDALTSKLPMFYLVNRP 441
            +QGALL+HF+QP+Y+ S+ +G     G+   TR +   +  R   A    L   ++VN P
Sbjct: 1022 LQGALLTHFLQPIYLKSVTLGYLFSQGHL--TRAICCRV-TRDGSAFEDGLRHPFIVNHP 1078

Query: 442  HISLVPSAYPLQMNLEYKFLSLNWAQGD-VSLEIVDGLSGKITESSPFKSGMSMASRLCK 500
             +  V      + + + K  S+NW   D   LEI+DG  G +          +  SR+ K
Sbjct: 1079 KVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV------DGPRNELSRVSK 1132

Query: 501  AAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSWIVK 556
              +   F  L     +  L   +Y  AK  +  Y+ AK   K  L+  GYG+WI K
Sbjct: 1133 KNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWISK 1188



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 19/69 (27%), Positives = 34/69 (49%)

Query: 96  NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 155
           NP+S L ++AQ      +      +G    P F F  V++G ++      +KK ++ +AA
Sbjct: 503 NPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAA 562

Query: 156 KLALDELLQ 164
             A+  LL+
Sbjct: 563 MKAMTILLE 571


>gi|70167113 adenosine deaminase, RNA-specific isoform d [Homo
           sapiens]
          Length = 931

 Score =  126 bits (317), Expect = 5e-29
 Identities = 142/542 (26%), Positives = 236/542 (43%), Gaps = 53/542 (9%)

Query: 54  TQVTGNFPEPLLSKNLSSISNPVLPPKKIPK-EFIMKYKRGEINPVSALHQFAQMQRVQL 112
           +  + N PE ++S++L ++ +  + P K+ K   +++Y     NPV  L ++A+      
Sbjct: 392 SMASDNQPEGMISESLDNLES--MMPNKVRKIGELVRYLN--TNPVGGLLEYARSHGFAA 447

Query: 113 DLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 172
           + K    +G    P F + A V G  +      +KK+ +  AA  AL  L+  +E   R+
Sbjct: 448 EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 507

Query: 173 LETSGPPPFPAE----PVVLSEL--AYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSE 226
             T   P   A      ++LS    A    +   G    + +I+ +    FN L ++   
Sbjct: 508 GFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTF-HDQIAMLSHRCFNTLTNSFQP 566

Query: 227 YLKYSSSLAAFIIERAGQHE--VVAIGTGEYNYSQD-IKPDGRVLHDTHAVVTARRS--- 280
            L     LAA I+++  +    VV++GTG      D +   G  ++D HA + +RR    
Sbjct: 567 SLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIR 626

Query: 281 -----LLSKNPAMMEKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQI-------KSQ 328
                L+  N    + SIF        L +K+ ++  LY++  P G   +       ++ 
Sbjct: 627 FLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAM 686

Query: 329 LRLNPHSISAFEANEELCLHVAVE---GKIYLT---VYCPKDGVN---RISSMSSSDKLT 379
                     FE  ++  L   VE   G I +    +    DG+    R+ +MS SDK+ 
Sbjct: 687 ESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKIL 746

Query: 380 RWEVLGVQGALLSHFIQPVYISSILIG----DGNCSDTRGLEIAIKQRVDDALTSKLPMF 435
           RW VLG+QGALL+HF+QP+Y+ S+ +G     G+   TR +   +  R   A    L   
Sbjct: 747 RWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHL--TRAICCRV-TRDGSAFEDGLRHP 803

Query: 436 YLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD-VSLEIVDGLSGKITESSPFKSGMSM 494
           ++VN P +  V      + + + K  S+NW   D   LEI+DG  G +          + 
Sbjct: 804 FIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV------DGPRNE 857

Query: 495 ASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSWI 554
            SR+ K  +   F  L     +  L   +Y  AK  +  Y+ AK   K  L+  GYG+WI
Sbjct: 858 LSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWI 917

Query: 555 VK 556
            K
Sbjct: 918 SK 919



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 19/69 (27%), Positives = 34/69 (49%)

Query: 96  NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 155
           NP+S L ++AQ      +      +G    P F F  V++G ++      +KK ++ +AA
Sbjct: 208 NPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAA 267

Query: 156 KLALDELLQ 164
             A+  LL+
Sbjct: 268 MKAMTILLE 276


>gi|70166852 adenosine deaminase, RNA-specific isoform a [Homo
            sapiens]
          Length = 1226

 Score =  126 bits (317), Expect = 5e-29
 Identities = 142/542 (26%), Positives = 236/542 (43%), Gaps = 53/542 (9%)

Query: 54   TQVTGNFPEPLLSKNLSSISNPVLPPKKIPK-EFIMKYKRGEINPVSALHQFAQMQRVQL 112
            +  + N PE ++S++L ++ +  + P K+ K   +++Y     NPV  L ++A+      
Sbjct: 687  SMASDNQPEGMISESLDNLES--MMPNKVRKIGELVRYLN--TNPVGGLLEYARSHGFAA 742

Query: 113  DLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 172
            + K    +G    P F + A V G  +      +KK+ +  AA  AL  L+  +E   R+
Sbjct: 743  EFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAADAALRVLIGENEKAERM 802

Query: 173  LETSGPPPFPAE----PVVLSEL--AYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSE 226
              T   P   A      ++LS    A    +   G    + +I+ +    FN L ++   
Sbjct: 803  GFTEVTPVTGASLRRTMLLLSRSPEAQPKTLPLTGSTF-HDQIAMLSHRCFNTLTNSFQP 861

Query: 227  YLKYSSSLAAFIIERAGQHE--VVAIGTGEYNYSQD-IKPDGRVLHDTHAVVTARRS--- 280
             L     LAA I+++  +    VV++GTG      D +   G  ++D HA + +RR    
Sbjct: 862  SLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCHAEIISRRGFIR 921

Query: 281  -----LLSKNPAMMEKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQI-------KSQ 328
                 L+  N    + SIF        L +K+ ++  LY++  P G   +       ++ 
Sbjct: 922  FLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGALFDKSCSDRAM 981

Query: 329  LRLNPHSISAFEANEELCLHVAVE---GKIYLT---VYCPKDGVN---RISSMSSSDKLT 379
                      FE  ++  L   VE   G I +    +    DG+    R+ +MS SDK+ 
Sbjct: 982  ESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGERLRTMSCSDKIL 1041

Query: 380  RWEVLGVQGALLSHFIQPVYISSILIG----DGNCSDTRGLEIAIKQRVDDALTSKLPMF 435
            RW VLG+QGALL+HF+QP+Y+ S+ +G     G+   TR +   +  R   A    L   
Sbjct: 1042 RWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHL--TRAICCRV-TRDGSAFEDGLRHP 1098

Query: 436  YLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD-VSLEIVDGLSGKITESSPFKSGMSM 494
            ++VN P +  V      + + + K  S+NW   D   LEI+DG  G +          + 
Sbjct: 1099 FIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV------DGPRNE 1152

Query: 495  ASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKSYLQQHGYGSWI 554
             SR+ K  +   F  L     +  L   +Y  AK  +  Y+ AK   K  L+  GYG+WI
Sbjct: 1153 LSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKKGLKDMGYGNWI 1212

Query: 555  VK 556
             K
Sbjct: 1213 SK 1214



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 19/69 (27%), Positives = 34/69 (49%)

Query: 96  NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 155
           NP+S L ++AQ      +      +G    P F F  V++G ++      +KK ++ +AA
Sbjct: 503 NPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAA 562

Query: 156 KLALDELLQ 164
             A+  LL+
Sbjct: 563 MKAMTILLE 571


>gi|70167032 adenosine deaminase, RNA-specific isoform c [Homo
            sapiens]
          Length = 1181

 Score =  122 bits (305), Expect = 1e-27
 Identities = 129/493 (26%), Positives = 208/493 (42%), Gaps = 62/493 (12%)

Query: 96   NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 155
            NPV  L ++A+      + K    +G    P F + A V G  +      +KK+ +  AA
Sbjct: 707  NPVGGLLEYARSHGFAAEFKLVDQSGPPHEPKFVYQAKVGGRWFPAVCAHSKKQGKQEAA 766

Query: 156  KLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKE 215
              AL  L+  +E               AE +  +EL       ++       +I+ +   
Sbjct: 767  DAALRVLIGENEK--------------AERMGFTELPLTGSTFHD-------QIAMLSHR 805

Query: 216  RFNQLISNRSEYLKYSSSLAAFIIERAGQHE--VVAIGTGEYNYSQD-IKPDGRVLHDTH 272
             FN L ++    L     LAA I+++  +    VV++GTG      D +   G  ++D H
Sbjct: 806  CFNTLTNSFQPSLLGRKILAAIIMKKDSEDMGVVVSLGTGNRCVKGDSLSLKGETVNDCH 865

Query: 273  AVVTARRS--------LLSKNPAMMEKSIFCTEPTSNLLTLKQNINICLYMNQLPKGSAQ 324
            A + +RR         L+  N    + SIF        L +K+ ++  LY++  P G   
Sbjct: 866  AEIISRRGFIRFLYSELMKYNSQTAKDSIFEPAKGGEKLQIKKTVSFHLYISTAPCGDGA 925

Query: 325  I-------KSQLRLNPHSISAFEANEELCLHVAVE---GKIYLT---VYCPKDGVN---R 368
            +       ++           FE  ++  L   VE   G I +    +    DG+    R
Sbjct: 926  LFDKSCSDRAMESTESRHYPVFENPKQGKLRTKVENGEGTIPVESSDIVPTWDGIRLGER 985

Query: 369  ISSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIG----DGNCSDTRGLEIAIKQRV 424
            + +MS SDK+ RW VLG+QGALL+HF+QP+Y+ S+ +G     G+   TR +   +  R 
Sbjct: 986  LRTMSCSDKILRWNVLGLQGALLTHFLQPIYLKSVTLGYLFSQGHL--TRAICCRV-TRD 1042

Query: 425  DDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGD-VSLEIVDGLSGKIT 483
              A    L   ++VN P +  V      + + + K  S+NW   D   LEI+DG  G + 
Sbjct: 1043 GSAFEDGLRHPFIVNHPKVGRVSIYDSKRQSGKTKETSVNWCLADGYDLEILDGTRGTV- 1101

Query: 484  ESSPFKSGMSMASRLCKAAMLSRFNLLAKEAKKELLEAGTYHAAKCMSASYQEAKCKLKS 543
                     +  SR+ K  +   F  L     +  L   +Y  AK  +  Y+ AK   K 
Sbjct: 1102 -----DGPRNELSRVSKKNIFLLFKKLCSFRYRRDLLRLSYGEAKKAARDYETAKNYFKK 1156

Query: 544  YLQQHGYGSWIVK 556
             L+  GYG+WI K
Sbjct: 1157 GLKDMGYGNWISK 1169



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 19/69 (27%), Positives = 34/69 (49%)

Query: 96  NPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAA 155
           NP+S L ++AQ      +      +G    P F F  V++G ++      +KK ++ +AA
Sbjct: 503 NPISGLLEYAQFASQTCEFNMIEQSGPPHEPRFKFQVVINGREFPPAEAGSKKVAKQDAA 562

Query: 156 KLALDELLQ 164
             A+  LL+
Sbjct: 563 MKAMTILLE 571


>gi|7669479 RNA-specific adenosine deaminase B1 isoform 3 [Homo
           sapiens]
          Length = 714

 Score =  119 bits (298), Expect = 7e-27
 Identities = 142/534 (26%), Positives = 221/534 (41%), Gaps = 114/534 (21%)

Query: 75  PVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVV 134
           PVLPP   P         G+ NPV  L++     R  L       +G      F    VV
Sbjct: 223 PVLPPFPPPS--------GK-NPVMILNEL----RPGLKYDFLSESGESHAKSFVMSVVV 269

Query: 135 DGIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRILETSGPPPFPAEPVVLSELAYV 194
           DG Q+  G G+NKK +++ AA+ AL  +  L      + +T    P P+E + L    ++
Sbjct: 270 DG-QFFEGSGRNKKLAKARAAQSALAAIFNL-----HLDQTPSRQPIPSEGLQL----HL 319

Query: 195 SKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIERAGQ---HEVVAIG 251
            +V  +        +S++V  +F  L  N S        LA  ++         +V+++ 
Sbjct: 320 PQVLADA-------VSRLVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTDVKDAKVISVS 372

Query: 252 TGEYNYSQDIKPD-GRVLHDTHAVVTARRSLLS----------KNPAMMEKSIFCTEPTS 300
           TG    + +   D G  L+D HA + +RRSLL            N    ++SIF      
Sbjct: 373 TGTKCINGEYMSDRGLALNDCHAEIISRRSLLRFLYTQLELYLNNKDDQKRSIFQKSERG 432

Query: 301 NLLTLKQNINICLYMNQLP-----------------------------KGSAQIKSQLRL 331
               LK+N+   LY++  P                              GS Q +    L
Sbjct: 433 GF-RLKENVQFHLYISTSPCGDARIFSPHEPILEGSRSYTQAGVQWCNHGSLQPRPPGLL 491

Query: 332 NPHSISAFEA---NEELCLHVAVEGKIYLTVYCPK----------------DGV---NRI 369
           +  S S F+     E    H   + +  L                      DGV    R+
Sbjct: 492 SDPSTSTFQGAGTTEPADRHPNRKARGQLRTKIESGEGTIPVRSNASIQTWDGVLQGERL 551

Query: 370 SSMSSSDKLTRWEVLGVQGALLSHFIQPVYISSILIGDGNCSDTRGLEIAIKQRVDDALT 429
            +MS SDK+ RW V+G+QG+LLS F++P+Y SSI++G     D   L  A+ QR+ +   
Sbjct: 552 LTMSCSDKIARWNVVGIQGSLLSIFVEPIYFSSIILGSLYHGD--HLSRAMYQRISN--I 607

Query: 430 SKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSLEIVDGLSGKITESSPFK 489
             LP  Y +N+P +S + +A   Q      F S+NW  GD ++E+++  +G        K
Sbjct: 608 EDLPPLYTLNKPLLSGISNAEARQPGKAPNF-SVNWTVGDSAIEVINATTG--------K 658

Query: 490 SGMSMASRLCKAAMLSRFNLLAKEAKKELLEA-----GTYHAAKCMSASYQEAK 538
             +  ASRLCK A+  R+  +  +    LL +       YH +K  +  YQ AK
Sbjct: 659 DELGRASRLCKHALYCRWMRVHGKVPSHLLRSKITKPNVYHESKLAAKEYQAAK 712


>gi|6912230 adenosine deaminase, tRNA-specific 1 [Homo sapiens]
          Length = 502

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 56/220 (25%), Positives = 93/220 (42%), Gaps = 33/220 (15%)

Query: 367 NRISSMSSSDKLTRWEVLGVQGALLSHFI-QPVYISSILIGD-------------GNCSD 412
           +R  SMS SDK+ RW VLG QGALL H + +P+Y+S+++IG              G C +
Sbjct: 292 DRTRSMSCSDKMARWNVLGCQGALLMHLLEEPIYLSAVVIGKCPYSQEAMQRALIGRCQN 351

Query: 413 TRGLEIAIKQRVDDALTSKLPMFYLVNRPHISLVPSAYPLQMNLEYKFLSLNWAQGDVSL 472
              L      +    L S L    L  +   ++          L     +++W+   V  
Sbjct: 352 VSALPKGFGVQELKILQSDL----LFEQSRSAVQAKRADSPGRLVPCGAAISWSA--VPE 405

Query: 473 EIVDGLSGKITESSPFKS--GMSMASRLCKAAMLSRFNLLAKEAKKE-------LLEAGT 523
           + +D  +    + +  K+   +   S++ K  +   F  L     ++       + +  T
Sbjct: 406 QPLDVTANGFPQGTTKKTIGSLQARSQISKVELFRSFQKLLSRIARDKWPHSLRVQKLDT 465

Query: 524 YHAAKCMSASYQEAKCKLKSYLQQHGYGSWIVKSPCIEQF 563
           Y   K  ++SYQEA     S L++  +GSWI   P   QF
Sbjct: 466 YQEYKEAASSYQEA----WSTLRKQVFGSWIRNPPDYHQF 501



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 26/88 (29%), Positives = 43/88 (48%), Gaps = 8/88 (9%)

Query: 246 EVVAIGTGEYNYSQD-IKPDGRVLHDTHAVVTARRSL-------LSKNPAMMEKSIFCTE 297
           E+V++GTG     Q  ++ +G +L+D+HA V ARRS        L     + E SIF   
Sbjct: 60  EIVSMGTGTKCIGQSKMRKNGDILNDSHAEVIARRSFQRYLLHQLQLAATLKEDSIFVPG 119

Query: 298 PTSNLLTLKQNINICLYMNQLPKGSAQI 325
               +  L++++    + +  P G A I
Sbjct: 120 TQKGVWKLRRDLIFVFFSSHTPCGDASI 147


>gi|208431829 eukaryotic translation initiation factor 2-alpha
           kinase 2 isoform b [Homo sapiens]
          Length = 510

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 22/62 (35%), Positives = 37/62 (59%)

Query: 101 LHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALD 160
           L+ + Q Q V L  +E   +G      F F  ++DG ++  G G++KKE+++ AAKLA++
Sbjct: 14  LNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVE 73

Query: 161 EL 162
            L
Sbjct: 74  IL 75



 Score = 30.0 bits (66), Expect = 5.9
 Identities = 19/69 (27%), Positives = 38/69 (55%), Gaps = 3/69 (4%)

Query: 96  NPVSALHQFAQMQRVQLDLKETVTTGNVMGPY-FAFCAVVDGIQYKTGLGQNKKESRSNA 154
           N +  +++ AQ +R+ ++ ++  +   V GP  F +   +   +Y  G G  K+E++  A
Sbjct: 100 NYIGLINRIAQKKRLTVNYEQCAS--GVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLA 157

Query: 155 AKLALDELL 163
           AKLA  ++L
Sbjct: 158 AKLAYLQIL 166


>gi|208431827 eukaryotic translation initiation factor 2-alpha
           kinase 2 isoform a [Homo sapiens]
          Length = 551

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 22/62 (35%), Positives = 37/62 (59%)

Query: 101 LHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALD 160
           L+ + Q Q V L  +E   +G      F F  ++DG ++  G G++KKE+++ AAKLA++
Sbjct: 14  LNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVE 73

Query: 161 EL 162
            L
Sbjct: 74  IL 75



 Score = 30.0 bits (66), Expect = 5.9
 Identities = 19/69 (27%), Positives = 38/69 (55%), Gaps = 3/69 (4%)

Query: 96  NPVSALHQFAQMQRVQLDLKETVTTGNVMGPY-FAFCAVVDGIQYKTGLGQNKKESRSNA 154
           N +  +++ AQ +R+ ++ ++  +   V GP  F +   +   +Y  G G  K+E++  A
Sbjct: 100 NYIGLINRIAQKKRLTVNYEQCAS--GVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLA 157

Query: 155 AKLALDELL 163
           AKLA  ++L
Sbjct: 158 AKLAYLQIL 166


>gi|4506103 eukaryotic translation initiation factor 2-alpha kinase
           2 isoform a [Homo sapiens]
          Length = 551

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 22/62 (35%), Positives = 37/62 (59%)

Query: 101 LHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALD 160
           L+ + Q Q V L  +E   +G      F F  ++DG ++  G G++KKE+++ AAKLA++
Sbjct: 14  LNTYRQKQGVVLKYQELPNSGPPHDRRFTFQVIIDGREFPEGEGRSKKEAKNAAAKLAVE 73

Query: 161 EL 162
            L
Sbjct: 74  IL 75



 Score = 30.0 bits (66), Expect = 5.9
 Identities = 19/69 (27%), Positives = 38/69 (55%), Gaps = 3/69 (4%)

Query: 96  NPVSALHQFAQMQRVQLDLKETVTTGNVMGPY-FAFCAVVDGIQYKTGLGQNKKESRSNA 154
           N +  +++ AQ +R+ ++ ++  +   V GP  F +   +   +Y  G G  K+E++  A
Sbjct: 100 NYIGLINRIAQKKRLTVNYEQCAS--GVHGPEGFHYKCKMGQKEYSIGTGSTKQEAKQLA 157

Query: 155 AKLALDELL 163
           AKLA  ++L
Sbjct: 158 AKLAYLQIL 166


>gi|7657625 staufen homolog 2 [Homo sapiens]
          Length = 479

 Score = 40.4 bits (93), Expect = 0.004
 Identities = 46/162 (28%), Positives = 68/162 (41%), Gaps = 16/162 (9%)

Query: 16  FAQMLKKNLPVQ---------PATKTITTPTG---WSSESYGLSKMASKVTQVTGNFPEP 63
           F   LK+N+PV          P  K+  T      +S+E  G SK  SK    T    E 
Sbjct: 181 FEIALKRNMPVSFEVIKESGPPHMKSFVTRVSVGEFSAEGEGNSKKLSKKRAATTVLQEL 240

Query: 64  LLSKNLSSISNPVLPPKKIPKEFIM---KYKRGEINPVSALHQFAQMQRVQLDLKETVTT 120
                L  +  P L  KK PK  +    +Y +G +NP+S L Q  Q ++ +      ++ 
Sbjct: 241 KKLPPLPVVEKPKLFFKKRPKTIVKAGPEYGQG-MNPISRLAQIQQAKKEKEPDYVLLSE 299

Query: 121 GNVMGPYFAFCAVVDGIQYKTGLGQNKKESRSNAAKLALDEL 162
             +         V  G +  TG G NKK ++ NAA+  L +L
Sbjct: 300 RGMPRRREFVMQVKVGNEVATGTGPNKKIAKKNAAEAMLLQL 341


>gi|57529737 PDZ domain containing ring finger 3 [Homo sapiens]
          Length = 1066

 Score = 35.8 bits (81), Expect = 0.11
 Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 15/110 (13%)

Query: 8   FQSSQVPSFAQMLKKNLPVQPATKTITTPTGWSSESYGLSKMASKVTQVTGNFPEPLLSK 67
           F++++ P   Q+L++     P TK  T P+         S++    TQ    F   +   
Sbjct: 324 FKTAKEPIVVQVLRRT----PRTKMFTPPSE--------SQLVDTGTQTDITFEHIMALT 371

Query: 68  NLSSISNPVLPPKKIPKEFIMKYKRGEINP-VSALHQFAQMQRVQLDLKE 116
            +SS S PVL P  +P+E    ++  + N  +  +HQ  +M R +L+L+E
Sbjct: 372 KMSSPSPPVLDPYLLPEEHPSAHEYYDPNDYIGDIHQ--EMDREELELEE 419


>gi|82659089 staufen isoform a [Homo sapiens]
          Length = 496

 Score = 35.4 bits (80), Expect = 0.14
 Identities = 55/214 (25%), Positives = 82/214 (38%), Gaps = 41/214 (19%)

Query: 16  FAQMLKKNLPVQ---------PATKTITTPTG---WSSESYGLSKMASKVTQVTGNFPE- 62
           F   LK+NLPV          P  K   T      +  E  G SK  SK         E 
Sbjct: 109 FEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL 168

Query: 63  ----PL-----LSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLD 113
               PL     +   +   + P++ P+  P+     Y +G INP+S L Q  Q ++ + +
Sbjct: 169 KKLPPLPAVERVKPRIKKKTKPIVKPQTSPE-----YGQG-INPISRLAQIQQAKK-EKE 221

Query: 114 LKETVTTGNVMGPYFAFCAVVD-GIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 172
            + T+ T   +     F   V  G     G G NKK ++ NAA+  L+           I
Sbjct: 222 PEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLE-----------I 270

Query: 173 LETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQY 206
           L    P   P +P + SE     K   +GR + +
Sbjct: 271 LGFKVPQAQPTKPALKSEEKTPIKKPGDGRKVTF 304


>gi|82659087 staufen isoform b [Homo sapiens]
          Length = 577

 Score = 35.4 bits (80), Expect = 0.14
 Identities = 55/214 (25%), Positives = 82/214 (38%), Gaps = 41/214 (19%)

Query: 16  FAQMLKKNLPVQ---------PATKTITTPTG---WSSESYGLSKMASKVTQVTGNFPE- 62
           F   LK+NLPV          P  K   T      +  E  G SK  SK         E 
Sbjct: 190 FEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL 249

Query: 63  ----PL-----LSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLD 113
               PL     +   +   + P++ P+  P+     Y +G INP+S L Q  Q ++ + +
Sbjct: 250 KKLPPLPAVERVKPRIKKKTKPIVKPQTSPE-----YGQG-INPISRLAQIQQAKK-EKE 302

Query: 114 LKETVTTGNVMGPYFAFCAVVD-GIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 172
            + T+ T   +     F   V  G     G G NKK ++ NAA+  L+           I
Sbjct: 303 PEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLE-----------I 351

Query: 173 LETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQY 206
           L    P   P +P + SE     K   +GR + +
Sbjct: 352 LGFKVPQAQPTKPALKSEEKTPIKKPGDGRKVTF 385


>gi|82659085 staufen isoform a [Homo sapiens]
          Length = 496

 Score = 35.4 bits (80), Expect = 0.14
 Identities = 55/214 (25%), Positives = 82/214 (38%), Gaps = 41/214 (19%)

Query: 16  FAQMLKKNLPVQ---------PATKTITTPTG---WSSESYGLSKMASKVTQVTGNFPE- 62
           F   LK+NLPV          P  K   T      +  E  G SK  SK         E 
Sbjct: 109 FEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL 168

Query: 63  ----PL-----LSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLD 113
               PL     +   +   + P++ P+  P+     Y +G INP+S L Q  Q ++ + +
Sbjct: 169 KKLPPLPAVERVKPRIKKKTKPIVKPQTSPE-----YGQG-INPISRLAQIQQAKK-EKE 221

Query: 114 LKETVTTGNVMGPYFAFCAVVD-GIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 172
            + T+ T   +     F   V  G     G G NKK ++ NAA+  L+           I
Sbjct: 222 PEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLE-----------I 270

Query: 173 LETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQY 206
           L    P   P +P + SE     K   +GR + +
Sbjct: 271 LGFKVPQAQPTKPALKSEEKTPIKKPGDGRKVTF 304


>gi|82659083 staufen isoform a [Homo sapiens]
          Length = 496

 Score = 35.4 bits (80), Expect = 0.14
 Identities = 55/214 (25%), Positives = 82/214 (38%), Gaps = 41/214 (19%)

Query: 16  FAQMLKKNLPVQ---------PATKTITTPTG---WSSESYGLSKMASKVTQVTGNFPE- 62
           F   LK+NLPV          P  K   T      +  E  G SK  SK         E 
Sbjct: 109 FEIALKRNLPVNFEVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAIAVLEEL 168

Query: 63  ----PL-----LSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLD 113
               PL     +   +   + P++ P+  P+     Y +G INP+S L Q  Q ++ + +
Sbjct: 169 KKLPPLPAVERVKPRIKKKTKPIVKPQTSPE-----YGQG-INPISRLAQIQQAKK-EKE 221

Query: 114 LKETVTTGNVMGPYFAFCAVVD-GIQYKTGLGQNKKESRSNAAKLALDELLQLDEPEPRI 172
            + T+ T   +     F   V  G     G G NKK ++ NAA+  L+           I
Sbjct: 222 PEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLE-----------I 270

Query: 173 LETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQY 206
           L    P   P +P + SE     K   +GR + +
Sbjct: 271 LGFKVPQAQPTKPALKSEEKTPIKKPGDGRKVTF 304


>gi|82659091 staufen isoform c [Homo sapiens]
          Length = 502

 Score = 33.1 bits (74), Expect = 0.70
 Identities = 55/220 (25%), Positives = 82/220 (37%), Gaps = 47/220 (21%)

Query: 16  FAQMLKKNLPVQ---------------PATKTITTPTG---WSSESYGLSKMASKVTQVT 57
           F   LK+NLPV                P  K   T      +  E  G SK  SK     
Sbjct: 109 FEIALKRNLPVNFESFPLKQVARESGPPHMKNFVTKVSVGEFVGEGEGKSKKISKKNAAI 168

Query: 58  GNFPE-----PL-----LSKNLSSISNPVLPPKKIPKEFIMKYKRGEINPVSALHQFAQM 107
               E     PL     +   +   + P++ P+  P+     Y +G INP+S L Q  Q 
Sbjct: 169 AVLEELKKLPPLPAVERVKPRIKKKTKPIVKPQTSPE-----YGQG-INPISRLAQIQQA 222

Query: 108 QRVQLDLKETVTTGNVMGPYFAFCAVVD-GIQYKTGLGQNKKESRSNAAKLALDELLQLD 166
           ++ + + + T+ T   +     F   V  G     G G NKK ++ NAA+  L+      
Sbjct: 223 KK-EKEPEYTLLTERGLPRRREFVMQVKVGNHTAEGTGTNKKVAKRNAAENMLE------ 275

Query: 167 EPEPRILETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQY 206
                IL    P   P +P + SE     K   +GR + +
Sbjct: 276 -----ILGFKVPQAQPTKPALKSEEKTPIKKPGDGRKVTF 310


>gi|24234756 interleukin enhancer binding factor 3 isoform c [Homo
           sapiens]
          Length = 690

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 41/175 (23%), Positives = 70/175 (40%), Gaps = 16/175 (9%)

Query: 21  KKNLPVQPATKTITT---PTGWSSESYGLSKMASKVTQVTGNFPEPLLSKNLSSISNPVL 77
           KK   +  A K +     PTG         + +++ T+       P       S  +   
Sbjct: 450 KKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAF 509

Query: 78  PPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGI 137
           P     ++  +  K G+ NPV  L++    +R  L  +    TG      F     VDG 
Sbjct: 510 PSDATAEQGPILTKHGK-NPVMELNE----KRRGLKYELISETGGSHDKRFVMEVEVDGQ 564

Query: 138 QYKTGLGQNKKESRSNAAKLALDEL-------LQLDEPEPRILETSGPPPFPAEP 185
           +++ G G NKK +++ AA  AL++L       L  ++ +   +   G P F A+P
Sbjct: 565 KFQ-GAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRAPVPVRGGPKFAAKP 618


>gi|24234753 interleukin enhancer binding factor 3 isoform b [Homo
           sapiens]
          Length = 702

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 41/175 (23%), Positives = 70/175 (40%), Gaps = 16/175 (9%)

Query: 21  KKNLPVQPATKTITT---PTGWSSESYGLSKMASKVTQVTGNFPEPLLSKNLSSISNPVL 77
           KK   +  A K +     PTG         + +++ T+       P       S  +   
Sbjct: 450 KKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAF 509

Query: 78  PPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGI 137
           P     ++  +  K G+ NPV  L++    +R  L  +    TG      F     VDG 
Sbjct: 510 PSDATAEQGPILTKHGK-NPVMELNE----KRRGLKYELISETGGSHDKRFVMEVEVDGQ 564

Query: 138 QYKTGLGQNKKESRSNAAKLALDEL-------LQLDEPEPRILETSGPPPFPAEP 185
           +++ G G NKK +++ AA  AL++L       L  ++ +   +   G P F A+P
Sbjct: 565 KFQ-GAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRAPVPVRGGPKFAAKP 618


>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
           sapiens]
          Length = 894

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 41/175 (23%), Positives = 70/175 (40%), Gaps = 16/175 (9%)

Query: 21  KKNLPVQPATKTITT---PTGWSSESYGLSKMASKVTQVTGNFPEPLLSKNLSSISNPVL 77
           KK   +  A K +     PTG         + +++ T+       P       S  +   
Sbjct: 450 KKTAKLHVAVKVLQDMGLPTGAEGRDSSKGEDSAEETEAKPAVVAPAPVVEAVSTPSAAF 509

Query: 78  PPKKIPKEFIMKYKRGEINPVSALHQFAQMQRVQLDLKETVTTGNVMGPYFAFCAVVDGI 137
           P     ++  +  K G+ NPV  L++    +R  L  +    TG      F     VDG 
Sbjct: 510 PSDATAEQGPILTKHGK-NPVMELNE----KRRGLKYELISETGGSHDKRFVMEVEVDGQ 564

Query: 138 QYKTGLGQNKKESRSNAAKLALDEL-------LQLDEPEPRILETSGPPPFPAEP 185
           +++ G G NKK +++ AA  AL++L       L  ++ +   +   G P F A+P
Sbjct: 565 KFQ-GAGSNKKVAKAYAALAALEKLFPDTPLALDANKKKRAPVPVRGGPKFAAKP 618


>gi|27545313 ubiquitin specific peptidase 38 [Homo sapiens]
          Length = 1042

 Score = 32.0 bits (71), Expect = 1.6
 Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 6/84 (7%)

Query: 174 ETSGPPPFPAEPVVLSELAYVSKVHYEGRHIQYAKISQIVK------ERFNQLISNRSEY 227
           +  G P   A  V L+EL +    HY G    Y  I + +K      E   +LI N+S +
Sbjct: 363 KNDGLPSSTAFLVQLTELIHCMMYHYSGFPDLYEPILEAIKDFPKPSEEKIKLILNQSAW 422

Query: 228 LKYSSSLAAFIIERAGQHEVVAIG 251
              S+SLA+ +   +G+ E    G
Sbjct: 423 TSQSNSLASCLSRLSGKSETGKTG 446


>gi|189409142 telomeric repeat binding factor 1 isoform 1 [Homo
           sapiens]
          Length = 439

 Score = 31.6 bits (70), Expect = 2.0
 Identities = 36/144 (25%), Positives = 63/144 (43%), Gaps = 21/144 (14%)

Query: 182 PAEPVVLSELAYVSKVHYEGRHIQYAKISQIVKERFNQLISNRSEYLKYSSSLAAFIIER 241
           P +  +L  ++     H   +H  Y  + + +K   N ++S +S    +    AA ++E 
Sbjct: 209 PFKSKLLMIISQKDTFHSFFQHFSYNHMMEKIKSYVNYVLSEKSS--TFLMKAAAKVVES 266

Query: 242 AGQHEVVAIGTGEYNYSQDIKPDGR-VLHDTHAVVTARRSLLSKNPAMMEKSIFCTEPTS 300
                +          SQD KP G  V  +T A +  R+S+  K  A+ E S    E T 
Sbjct: 267 KRTRTIT---------SQD-KPSGNDVEMETEANLDTRKSVSDKQSAVTESS----EGTV 312

Query: 301 NLLTLKQNINICLYMNQLPKGSAQ 324
           +LL   +N    L++++L  G+ Q
Sbjct: 313 SLLRSHKN----LFLSKLQHGTQQ 332


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,910,325
Number of Sequences: 37866
Number of extensions: 913333
Number of successful extensions: 2426
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 2337
Number of HSP's gapped (non-prelim): 69
length of query: 565
length of database: 18,247,518
effective HSP length: 108
effective length of query: 457
effective length of database: 14,157,990
effective search space: 6470201430
effective search space used: 6470201430
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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