Guide to the Human Genome
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Search of human proteins with 226491350

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226491350 tubulin polymerization-promoting protein family
member 2 [Homo sapiens]
         (170 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226491350 tubulin polymerization-promoting protein family mem...   343   5e-95
gi|56676377 tubulin polymerization-promoting protein family memb...   224   4e-59
gi|56676375 tubulin polymerization-promoting protein family memb...   224   4e-59
gi|5902018 tubulin polymerization promoting protein [Homo sapiens]    210   4e-55
gi|29171734 eukaryotic translation initiation factor 2C, 2 [Homo...    30   1.3  
gi|217416415 RAD51-like 3 isoform 1 [Homo sapiens]                     28   2.9  
gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member ...    28   3.8  
gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member ...    28   3.8  
gi|148886696 surfactant protein A2 [Homo sapiens]                      28   5.0  
gi|147903070 surfactant protein A1 [Homo sapiens]                      28   5.0  
gi|38888175 surfactant, pulmonary-associated protein A1B [Homo s...    28   5.0  
gi|146149162 surfactant, pulmonary-associated protein A2 [Homo s...    28   5.0  
gi|7661926 SERTA domain containing 2 [Homo sapiens]                    28   5.0  
gi|191251777 breast carcinoma amplified sequence 1 [Homo sapiens]      27   6.5  
gi|6912352 eukaryotic translation initiation factor 2C, 1 [Homo ...    27   8.5  

>gi|226491350 tubulin polymerization-promoting protein family member
           2 [Homo sapiens]
          Length = 170

 Score =  343 bits (879), Expect = 5e-95
 Identities = 170/170 (100%), Positives = 170/170 (100%)

Query: 1   MASEAEKTFHRFAAFGESSSSGTEMNNKNFSKLCKDCGIMDGKTVTSTDVDIVFSKVKAK 60
           MASEAEKTFHRFAAFGESSSSGTEMNNKNFSKLCKDCGIMDGKTVTSTDVDIVFSKVKAK
Sbjct: 1   MASEAEKTFHRFAAFGESSSSGTEMNNKNFSKLCKDCGIMDGKTVTSTDVDIVFSKVKAK 60

Query: 61  NARTITFQQFKEAVKELGQKRFKGKSPDEVLENIYGLMEGKDPATTGATKATTVGAVDRL 120
           NARTITFQQFKEAVKELGQKRFKGKSPDEVLENIYGLMEGKDPATTGATKATTVGAVDRL
Sbjct: 61  NARTITFQQFKEAVKELGQKRFKGKSPDEVLENIYGLMEGKDPATTGATKATTVGAVDRL 120

Query: 121 TDTSKYTGTHKERFDESGKGKGIAGREEMTDNTGYVSGYKGSGTYDKKTK 170
           TDTSKYTGTHKERFDESGKGKGIAGREEMTDNTGYVSGYKGSGTYDKKTK
Sbjct: 121 TDTSKYTGTHKERFDESGKGKGIAGREEMTDNTGYVSGYKGSGTYDKKTK 170


>gi|56676377 tubulin polymerization-promoting protein family member
           3 [Homo sapiens]
          Length = 176

 Score =  224 bits (570), Expect = 4e-59
 Identities = 105/165 (63%), Positives = 133/165 (80%)

Query: 6   EKTFHRFAAFGESSSSGTEMNNKNFSKLCKDCGIMDGKTVTSTDVDIVFSKVKAKNARTI 65
           E++F +FA  G+  +SG EMN KN++KLCKDC + DGK+VT TDVDIVFSKVK K+AR I
Sbjct: 11  EESFRKFAIHGDPKASGQEMNGKNWAKLCKDCKVADGKSVTGTDVDIVFSKVKGKSARVI 70

Query: 66  TFQQFKEAVKELGQKRFKGKSPDEVLENIYGLMEGKDPATTGATKATTVGAVDRLTDTSK 125
            +++FK+A++EL  KRFKGKS +E  + I  L+ GK+PA  G TKA T GAVDRLTDTS+
Sbjct: 71  NYEEFKKALEELATKRFKGKSKEEAFDAICQLVAGKEPANVGVTKAKTGGAVDRLTDTSR 130

Query: 126 YTGTHKERFDESGKGKGIAGREEMTDNTGYVSGYKGSGTYDKKTK 170
           YTG+HKERFDESGKGKGIAGR+++ D++GYVS YK +GTYD K K
Sbjct: 131 YTGSHKERFDESGKGKGIAGRQDILDDSGYVSAYKNAGTYDAKVK 175


>gi|56676375 tubulin polymerization-promoting protein family member
           3 [Homo sapiens]
          Length = 176

 Score =  224 bits (570), Expect = 4e-59
 Identities = 105/165 (63%), Positives = 133/165 (80%)

Query: 6   EKTFHRFAAFGESSSSGTEMNNKNFSKLCKDCGIMDGKTVTSTDVDIVFSKVKAKNARTI 65
           E++F +FA  G+  +SG EMN KN++KLCKDC + DGK+VT TDVDIVFSKVK K+AR I
Sbjct: 11  EESFRKFAIHGDPKASGQEMNGKNWAKLCKDCKVADGKSVTGTDVDIVFSKVKGKSARVI 70

Query: 66  TFQQFKEAVKELGQKRFKGKSPDEVLENIYGLMEGKDPATTGATKATTVGAVDRLTDTSK 125
            +++FK+A++EL  KRFKGKS +E  + I  L+ GK+PA  G TKA T GAVDRLTDTS+
Sbjct: 71  NYEEFKKALEELATKRFKGKSKEEAFDAICQLVAGKEPANVGVTKAKTGGAVDRLTDTSR 130

Query: 126 YTGTHKERFDESGKGKGIAGREEMTDNTGYVSGYKGSGTYDKKTK 170
           YTG+HKERFDESGKGKGIAGR+++ D++GYVS YK +GTYD K K
Sbjct: 131 YTGSHKERFDESGKGKGIAGRQDILDDSGYVSAYKNAGTYDAKVK 175


>gi|5902018 tubulin polymerization promoting protein [Homo sapiens]
          Length = 219

 Score =  210 bits (535), Expect = 4e-55
 Identities = 98/168 (58%), Positives = 131/168 (77%)

Query: 3   SEAEKTFHRFAAFGESSSSGTEMNNKNFSKLCKDCGIMDGKTVTSTDVDIVFSKVKAKNA 62
           S  E+ F RFA  G++ ++G EM+ KN+SKLCKDC ++DG+ VT TDVDIVFSK+K K+ 
Sbjct: 49  SALEEAFRRFAVHGDARATGREMHGKNWSKLCKDCQVIDGRNVTVTDVDIVFSKIKGKSC 108

Query: 63  RTITFQQFKEAVKELGQKRFKGKSPDEVLENIYGLMEGKDPATTGATKATTVGAVDRLTD 122
           RTITF+QF+EA++EL +KRFK KS +E +  ++ L+EGK P  +G TKA +   V RLTD
Sbjct: 109 RTITFEQFQEALEELAKKRFKDKSSEEAVREVHRLIEGKAPIISGVTKAISSPTVSRLTD 168

Query: 123 TSKYTGTHKERFDESGKGKGIAGREEMTDNTGYVSGYKGSGTYDKKTK 170
           T+K+TG+HKERFD SGKGKG AGR ++ D +GYVSGYK +GTYD+K +
Sbjct: 169 TTKFTGSHKERFDPSGKGKGKAGRVDLVDESGYVSGYKHAGTYDQKVQ 216


>gi|29171734 eukaryotic translation initiation factor 2C, 2 [Homo
           sapiens]
          Length = 859

 Score = 29.6 bits (65), Expect = 1.3
 Identities = 25/84 (29%), Positives = 39/84 (46%), Gaps = 3/84 (3%)

Query: 76  ELGQKRFKGKSPDEVLENIYG---LMEGKDPATTGATKATTVGAVDRLTDTSKYTGTHKE 132
           ++GQ++     P EV   + G   + +  D  T+   +AT   A DR  + SK   +   
Sbjct: 329 QVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASF 388

Query: 133 RFDESGKGKGIAGREEMTDNTGYV 156
             D   +  GI  ++EMTD TG V
Sbjct: 389 NTDPYVREFGIMVKDEMTDVTGRV 412


>gi|217416415 RAD51-like 3 isoform 1 [Homo sapiens]
          Length = 328

 Score = 28.5 bits (62), Expect = 2.9
 Identities = 14/37 (37%), Positives = 20/37 (54%)

Query: 105 TTGATKATTVGAVDRLTDTSKYTGTHKERFDESGKGK 141
           T+ A  +T +G++D+L D   YTG   E     G GK
Sbjct: 77  TSTAILSTGIGSLDKLLDAGLYTGEVTEIVGGPGSGK 113


>gi|239757009 PREDICTED: ankyrin repeat domain 20 family, member A5
           [Homo sapiens]
          Length = 823

 Score = 28.1 bits (61), Expect = 3.8
 Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 2/99 (2%)

Query: 43  KTVTSTDVDIVFSKVKAKNARTITFQQFKEAVKELGQKRFKG--KSPDEVLENIYGLMEG 100
           K  T  +   V   V+ KN +T+  +Q      E  Q+R +   K   +V+E        
Sbjct: 336 KPSTEMEDPAVKGAVQXKNVQTLRAEQALPVASEEEQQRRERSEKKQPQVIEGNNTYKSE 395

Query: 101 KDPATTGATKATTVGAVDRLTDTSKYTGTHKERFDESGK 139
           K   +     +T   A DRLT   K   T+ ++F +  K
Sbjct: 396 KIQLSENICHSTFSAAADRLTQQRKIGKTYPQQFPKKLK 434


>gi|239751523 PREDICTED: ankyrin repeat domain 20 family, member A5
           [Homo sapiens]
          Length = 823

 Score = 28.1 bits (61), Expect = 3.8
 Identities = 25/99 (25%), Positives = 40/99 (40%), Gaps = 2/99 (2%)

Query: 43  KTVTSTDVDIVFSKVKAKNARTITFQQFKEAVKELGQKRFKG--KSPDEVLENIYGLMEG 100
           K  T  +   V   V+ KN +T+  +Q      E  Q+R +   K   +V+E        
Sbjct: 336 KPSTEMEDPAVKGAVQXKNVQTLRAEQALPVASEEEQQRRERSEKKQPQVIEGNNTYKSE 395

Query: 101 KDPATTGATKATTVGAVDRLTDTSKYTGTHKERFDESGK 139
           K   +     +T   A DRLT   K   T+ ++F +  K
Sbjct: 396 KIQLSENICHSTFSAAADRLTQQRKIGKTYPQQFPKKLK 434


>gi|148886696 surfactant protein A2 [Homo sapiens]
          Length = 248

 Score = 27.7 bits (60), Expect = 5.0
 Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 1/89 (1%)

Query: 53  VFSKVKAKNARTITFQQFKEAVKELGQKRFKGKSPDEVLENIYGLMEGKDPATTGATKAT 112
           V  KV + N ++ITF   +EA    G +    ++P+E       + +    A  G T+  
Sbjct: 134 VGEKVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYNTYAYVGLTEGP 193

Query: 113 TVGAVDRLTDTSKYTGTHKERFDESGKGK 141
           + G   R +D +    T+  R + +G+GK
Sbjct: 194 SPGDF-RYSDGTPVNYTNWYRGEPAGRGK 221


>gi|147903070 surfactant protein A1 [Homo sapiens]
          Length = 245

 Score = 27.7 bits (60), Expect = 5.0
 Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 1/89 (1%)

Query: 53  VFSKVKAKNARTITFQQFKEAVKELGQKRFKGKSPDEVLENIYGLMEGKDPATTGATKAT 112
           V  KV + N ++ITF   +EA    G +    ++P+E       + +    A  G T+  
Sbjct: 134 VGEKVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYNTYAYVGLTEGP 193

Query: 113 TVGAVDRLTDTSKYTGTHKERFDESGKGK 141
           + G   R +D +    T+  R + +G+GK
Sbjct: 194 SPGDF-RYSDGTPVNYTNWYRGEPAGRGK 221


>gi|38888175 surfactant, pulmonary-associated protein A1B [Homo
           sapiens]
          Length = 248

 Score = 27.7 bits (60), Expect = 5.0
 Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 1/89 (1%)

Query: 53  VFSKVKAKNARTITFQQFKEAVKELGQKRFKGKSPDEVLENIYGLMEGKDPATTGATKAT 112
           V  KV + N ++ITF   +EA    G +    ++P+E       + +    A  G T+  
Sbjct: 134 VGEKVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYNTYAYVGLTEGP 193

Query: 113 TVGAVDRLTDTSKYTGTHKERFDESGKGK 141
           + G   R +D +    T+  R + +G+GK
Sbjct: 194 SPGDF-RYSDGTPVNYTNWYRGEPAGRGK 221


>gi|146149162 surfactant, pulmonary-associated protein A2 [Homo
           sapiens]
          Length = 248

 Score = 27.7 bits (60), Expect = 5.0
 Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 1/89 (1%)

Query: 53  VFSKVKAKNARTITFQQFKEAVKELGQKRFKGKSPDEVLENIYGLMEGKDPATTGATKAT 112
           V  KV + N ++ITF   +EA    G +    ++P+E       + +    A  G T+  
Sbjct: 134 VGEKVFSSNGQSITFDAIQEACARAGGRIAVPRNPEENEAIASFVKKYNTYAYVGLTEGP 193

Query: 113 TVGAVDRLTDTSKYTGTHKERFDESGKGK 141
           + G   R +D +    T+  R + +G+GK
Sbjct: 194 SPGDF-RYSDGTPVNYTNWYRGEPAGRGK 221


>gi|7661926 SERTA domain containing 2 [Homo sapiens]
          Length = 314

 Score = 27.7 bits (60), Expect = 5.0
 Identities = 19/59 (32%), Positives = 30/59 (50%), Gaps = 7/59 (11%)

Query: 105 TTGATKATTVGAVDRLTDTSKYTGTHK------ERFDESGKGKGIAGREEMTDNTGYVS 157
           T+ +T+A T  A D +  TS   GT K       R D+S     + G  E+T +TG+++
Sbjct: 182 TSTSTEAATA-ATDSVKGTSSEAGTQKLDGPQESRADDSKLMDSLPGNFEITTSTGFLT 239


>gi|191251777 breast carcinoma amplified sequence 1 [Homo sapiens]
          Length = 584

 Score = 27.3 bits (59), Expect = 6.5
 Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 1/48 (2%)

Query: 101 KDPATTGATKATTVGAVDRLTDTSKYTGTHKERFDESGKGKGIAGREE 148
           KDP  TGA K+ T  A D  +D + +T    +   ++ KG   +G  +
Sbjct: 304 KDPEDTGAEKSPTTSA-DLKSDKANFTSQETQGAGKNSKGCNPSGHTQ 350


>gi|6912352 eukaryotic translation initiation factor 2C, 1 [Homo
           sapiens]
          Length = 857

 Score = 26.9 bits (58), Expect = 8.5
 Identities = 23/84 (27%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 76  ELGQKRFKGKSPDEVLENIYG---LMEGKDPATTGATKATTVGAVDRLTDTSKYTGTHKE 132
           ++GQ++     P EV   + G   + +  D  T+   KAT   A DR  + S+       
Sbjct: 327 QVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASY 386

Query: 133 RFDESGKGKGIAGREEMTDNTGYV 156
             D   +  GI  +++MT+ TG V
Sbjct: 387 NLDPYIQEFGIKVKDDMTEVTGRV 410


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.127    0.350 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,903,108
Number of Sequences: 37866
Number of extensions: 240181
Number of successful extensions: 524
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 518
Number of HSP's gapped (non-prelim): 15
length of query: 170
length of database: 18,247,518
effective HSP length: 95
effective length of query: 75
effective length of database: 14,650,248
effective search space: 1098768600
effective search space used: 1098768600
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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