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Search of human proteins with 226371741
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|226371741 phosphatidylinositol-5-phosphate 4-kinase, type
II, gamma isoform b [Homo sapiens]
(403 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|226371741 phosphatidylinositol-5-phosphate 4-kinase, type II,... 810 0.0
gi|226371739 phosphatidylinositol-5-phosphate 4-kinase, type II,... 798 0.0
gi|226371737 phosphatidylinositol-5-phosphate 4-kinase, type II,... 798 0.0
gi|226371743 phosphatidylinositol-5-phosphate 4-kinase, type II,... 682 0.0
gi|4505819 phosphatidylinositol-5-phosphate 4-kinase, type II, b... 493 e-140
gi|6857820 phosphatidylinositol-5-phosphate 4-kinase, type II, a... 481 e-136
gi|31317309 phosphatidylinositol-4-phosphate 5-kinase, type I, g... 160 1e-39
gi|208431778 phosphatidylinositol-4-phosphate 5-kinase, type I, ... 156 3e-38
gi|208431776 phosphatidylinositol-4-phosphate 5-kinase, type I, ... 156 3e-38
gi|4505815 phosphatidylinositol-4-phosphate 5-kinase, type I, al... 156 3e-38
gi|4505817 phosphatidylinositol-4-phosphate 5-kinase, type I, be... 154 1e-37
gi|208431774 phosphatidylinositol-4-phosphate 5-kinase, type I, ... 131 9e-31
gi|206725454 phosphatidylinositol-4-phosphate 5-kinase-like 1 is... 99 7e-21
gi|27735085 phosphatidylinositol-4-phosphate 5-kinase-like 1 iso... 65 8e-11
gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III ... 64 2e-10
gi|148227842 Myb-like, SWIRM and MPN domains 1 [Homo sapiens] 35 0.12
gi|6005997 double C2-like domains, beta [Homo sapiens] 33 0.60
gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens] 32 1.0
gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo s... 30 3.9
gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo s... 30 3.9
gi|154240677 hypothetical protein LOC399949 isoform 2 [Homo sapi... 30 3.9
gi|117553613 coiled-coil domain containing 151 [Homo sapiens] 30 3.9
gi|50053795 eukaryotic translation initiation factor 4B [Homo sa... 30 5.1
gi|4758220 XAP-5 protein [Homo sapiens] 29 6.6
gi|145580615 KRI1 homolog [Homo sapiens] 29 6.6
gi|21396500 HIRA interacting protein 3 [Homo sapiens] 29 6.6
>gi|226371741 phosphatidylinositol-5-phosphate 4-kinase, type II,
gamma isoform b [Homo sapiens]
Length = 403
Score = 810 bits (2091), Expect = 0.0
Identities = 403/403 (100%), Positives = 403/403 (100%)
Query: 1 MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN
Sbjct: 1 MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
Query: 61 ELSQVPPPVMLLPDDFKASSKIKEYCPQVFRNLRDRFGIDDQDYLVSLTRNPPSESEGSD 120
ELSQVPPPVMLLPDDFKASSKIKEYCPQVFRNLRDRFGIDDQDYLVSLTRNPPSESEGSD
Sbjct: 61 ELSQVPPPVMLLPDDFKASSKIKEYCPQVFRNLRDRFGIDDQDYLVSLTRNPPSESEGSD 120
Query: 121 GRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDS 180
GRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDS
Sbjct: 121 GRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDS 180
Query: 181 YMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEE 240
YMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEE
Sbjct: 181 YMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEE 240
Query: 241 KKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGP 300
KKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGP
Sbjct: 241 KKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGP 300
Query: 301 PALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQ 360
PALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQ
Sbjct: 301 PALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQ 360
Query: 361 YDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIFA 403
YDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIFA
Sbjct: 361 YDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIFA 403
>gi|226371739 phosphatidylinositol-5-phosphate 4-kinase, type II,
gamma isoform a [Homo sapiens]
Length = 421
Score = 798 bits (2062), Expect = 0.0
Identities = 403/421 (95%), Positives = 403/421 (95%), Gaps = 18/421 (4%)
Query: 1 MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN
Sbjct: 1 MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
Query: 61 ELSQVPPPVMLLPDDFKASSKIK------------------EYCPQVFRNLRDRFGIDDQ 102
ELSQVPPPVMLLPDDFKASSKIK EYCPQVFRNLRDRFGIDDQ
Sbjct: 61 ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 120
Query: 103 DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT 162
DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT
Sbjct: 121 DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT 180
Query: 163 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 222
LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL
Sbjct: 181 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 240
Query: 223 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 282
KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA
Sbjct: 241 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 300
Query: 283 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 342
PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE
Sbjct: 301 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 360
Query: 343 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 402
GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF
Sbjct: 361 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 420
Query: 403 A 403
A
Sbjct: 421 A 421
>gi|226371737 phosphatidylinositol-5-phosphate 4-kinase, type II,
gamma isoform a [Homo sapiens]
Length = 421
Score = 798 bits (2062), Expect = 0.0
Identities = 403/421 (95%), Positives = 403/421 (95%), Gaps = 18/421 (4%)
Query: 1 MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN
Sbjct: 1 MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
Query: 61 ELSQVPPPVMLLPDDFKASSKIK------------------EYCPQVFRNLRDRFGIDDQ 102
ELSQVPPPVMLLPDDFKASSKIK EYCPQVFRNLRDRFGIDDQ
Sbjct: 61 ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 120
Query: 103 DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT 162
DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT
Sbjct: 121 DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT 180
Query: 163 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 222
LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL
Sbjct: 181 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 240
Query: 223 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 282
KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA
Sbjct: 241 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 300
Query: 283 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 342
PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE
Sbjct: 301 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 360
Query: 343 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 402
GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF
Sbjct: 361 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 420
Query: 403 A 403
A
Sbjct: 421 A 421
>gi|226371743 phosphatidylinositol-5-phosphate 4-kinase, type II,
gamma isoform c [Homo sapiens]
Length = 373
Score = 682 bits (1759), Expect = 0.0
Identities = 355/421 (84%), Positives = 355/421 (84%), Gaps = 66/421 (15%)
Query: 1 MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN
Sbjct: 1 MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
Query: 61 ELSQVPPPVMLLPDDFKASSKIK------------------EYCPQVFRNLRDRFGIDDQ 102
ELSQVPPPVMLLPDDFKASSKIK EYCPQVFRNLRDRFGIDDQ
Sbjct: 61 ELSQVPPPVMLLPDDFKASSKIKVNNHLFHRENLPSHFKFKEYCPQVFRNLRDRFGIDDQ 120
Query: 103 DYLVSLTRNPPSESEGSDGRFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNT 162
DYL YIVKCHGNT
Sbjct: 121 DYL------------------------------------------------YIVKCHGNT 132
Query: 163 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 222
LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL
Sbjct: 133 LLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTL 192
Query: 223 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 282
KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA
Sbjct: 193 KDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEA 252
Query: 283 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 342
PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE
Sbjct: 253 PVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAE 312
Query: 343 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 402
GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF
Sbjct: 313 GAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNIF 372
Query: 403 A 403
A
Sbjct: 373 A 373
>gi|4505819 phosphatidylinositol-5-phosphate 4-kinase, type II, beta
[Homo sapiens]
Length = 416
Score = 493 bits (1270), Expect = e-140
Identities = 253/397 (63%), Positives = 307/397 (77%), Gaps = 24/397 (6%)
Query: 26 SKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIK-- 83
+KTKKKHFV QKVK+FRA++P++ V +WGV H+INELS VP PVML+PDDFKA SKIK
Sbjct: 21 TKTKKKHFVCQKVKLFRASEPILSVLMWGVNHTINELSNVPVPVMLMPDDFKAYSKIKVD 80
Query: 84 ----------------EYCPQVFRNLRDRFGIDDQDYLVSLTRNPP--SESEGSDG-RFL 124
EYCP VFRNLR+RFGIDDQDY S+TR+ P S+S+G G RFL
Sbjct: 81 NHLFNKENLPSRFKFKEYCPMVFRNLRERFGIDDQDYQNSVTRSAPINSDSQGRCGTRFL 140
Query: 125 ISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLV 184
+YDR VIK VSSED+A+MH+ L YHQ+IV+CHGNTLLPQFLGMYR++VD ++YM+V
Sbjct: 141 TTYDRRFVIKTVSSEDVAEMHNILKKYHQFIVECHGNTLLPQFLGMYRLTVDGVETYMVV 200
Query: 185 MRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIF 244
RN+FSHRL VHRKYDLKGS V+REASDKEK K+LPT KD DFLN+ QK+++GEE KK F
Sbjct: 201 TRNVFSHRLTVHRKYDLKGSTVAREASDKEKAKDLPTFKDNDFLNEGQKLHVGEESKKNF 260
Query: 245 LEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALV 304
LEKLKRDVEFL QLKIMDYSLL+GIHD+ R + E E R ++ E + D + G L+
Sbjct: 261 LEKLKRDVEFLAQLKIMDYSLLVGIHDVDRAEQEEMEVEERAEDEECEND-GVGG--NLL 317
Query: 305 GSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAK 364
SYGT P+ G + R GPGEF+ +DVYA++S E +P+KEVYFM +IDILT YD K
Sbjct: 318 CSYGTPPDSPGNLLSFPRFFGPGEFDPSVDVYAMKSHESSPKKEVYFMAIIDILTPYDTK 377
Query: 365 KKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNI 401
KKAAHAAKTVKHGAGAEISTV+PEQY+KRF +F++NI
Sbjct: 378 KKAAHAAKTVKHGAGAEISTVNPEQYSKRFNEFMSNI 414
>gi|6857820 phosphatidylinositol-5-phosphate 4-kinase, type II,
alpha [Homo sapiens]
Length = 406
Score = 481 bits (1237), Expect = e-136
Identities = 246/397 (61%), Positives = 298/397 (75%), Gaps = 29/397 (7%)
Query: 26 SKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVMLLPDDFKASSKIK-- 83
+KTKKKHFV QKVK+FRA+DPL+ V +WGV HSINELS V PVML+PDDFKA SKIK
Sbjct: 16 TKTKKKHFVAQKVKLFRASDPLLSVLMWGVNHSINELSHVQIPVMLMPDDFKAYSKIKVD 75
Query: 84 ----------------EYCPQVFRNLRDRFGIDDQDYLVSLTRNPPSESEG---SDGRFL 124
EYCP VFRNLR+RFGIDDQD+ SLTR+ P ++ S RF
Sbjct: 76 NHLFNKENMPSHFKFKEYCPMVFRNLRERFGIDDQDFQNSLTRSAPLPNDSQARSGARFH 135
Query: 125 ISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLV 184
SYD+ +IK ++SED+A+MH+ L YHQYIV+CHG TLLPQFLGMYR++VD + Y++V
Sbjct: 136 TSYDKRYIIKTITSEDVAEMHNILKKYHQYIVECHGITLLPQFLGMYRLNVDGVEIYVIV 195
Query: 185 MRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIF 244
RN+FSHRL V+RKYDLKGS V+REASDKEK KELPTLKD DF+N+ QK+YI + KK+F
Sbjct: 196 TRNVFSHRLSVYRKYDLKGSTVAREASDKEKAKELPTLKDNDFINEGQKIYIDDNNKKVF 255
Query: 245 LEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALV 304
LEKLK+DVEFL QLK+MDYSLL+GIHD+ R +EE E++ E +G+ T P
Sbjct: 256 LEKLKKDVEFLAQLKLMDYSLLVGIHDVERAE--QEEVECEENDGEEEGESDGTHP---- 309
Query: 305 GSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAK 364
GT P+ G ++S PL PGEF+ IDVY I+ E +P+KEVYFM +IDILT YDAK
Sbjct: 310 --VGTPPDSPGNTLNSSPPLAPGEFDPNIDVYGIKCHENSPRKEVYFMAIIDILTHYDAK 367
Query: 365 KKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITNI 401
KKAAHAAKTVKHGAGAEISTV+PEQY+KRFLDFI +I
Sbjct: 368 KKAAHAAKTVKHGAGAEISTVNPEQYSKRFLDFIGHI 404
>gi|31317309 phosphatidylinositol-4-phosphate 5-kinase, type I,
gamma [Homo sapiens]
Length = 668
Score = 160 bits (406), Expect = 1e-39
Identities = 129/424 (30%), Positives = 194/424 (45%), Gaps = 39/424 (9%)
Query: 1 MASSSVPPATVSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSIN 60
+A P V + TA PGPG G + + + L G G+ +++
Sbjct: 33 LAQKKAAPTEVLSMTAQPGPGHGKKLGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVG 92
Query: 61 ELSQVPPPVMLLPDDFKASS-------------------KIKEYCPQVFRNLRDRFGIDD 101
LS P +L+ D + S + K Y P FR R+ FGI
Sbjct: 93 HLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFQDFRFKTYAPVAFRYFRELFGIRP 152
Query: 102 QDYLVSLTRNPPSE--SEGSDGR-FLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKC 158
DYL SL P E + G+ G F ++ D +IK V ++ + L Y+ + +
Sbjct: 153 DDYLYSLCNEPLIELSNPGASGSLFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQ- 211
Query: 159 HGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKE 218
+ TLLP+F G+Y V ++ ++VM N+ + +H K+DLKGS R AS KEK K
Sbjct: 212 NPRTLLPKFYGLYCVQSGGKNIRVVVMNNILPRVVKMHLKFDLKGSTYKRRASKKEKEKS 271
Query: 219 LPTLKDMDFL-NKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSE 277
PT KD+DF+ + + + + + ++ L+RD L KIMDYSLLLG+H+I +
Sbjct: 272 FPTYKDLDFMQDMPEGLLLDADTFSALVKTLQRDCLVLESFKIMDYSLLLGVHNI---DQ 328
Query: 278 PEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGE-FESFIDVY 336
E E + +S D + G AL Y T+ E I G GE ES +
Sbjct: 329 HERERQAQGAQSTSD-EKRPVGQKAL---YSTAMESIQG------GAARGEAIESDDTMG 378
Query: 337 AIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLD 396
I + G ++ + +G+IDIL Y KK H K + H G +S P YA+RF
Sbjct: 379 GIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHTWKALVHD-GDTVSVHRPSFYAERFFK 437
Query: 397 FITN 400
F++N
Sbjct: 438 FMSN 441
>gi|208431778 phosphatidylinositol-4-phosphate 5-kinase, type I,
alpha isoform 1 [Homo sapiens]
Length = 562
Score = 156 bits (395), Expect = 3e-38
Identities = 119/377 (31%), Positives = 174/377 (46%), Gaps = 37/377 (9%)
Query: 47 LVGVFLWGVAHSINELSQVPPPVMLLPDDFKASS-------------------KIKEYCP 87
L G G+ H++ LS P +L+ D + S + K Y P
Sbjct: 85 LKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAP 144
Query: 88 QVFRNLRDRFGIDDQDYLVSLTRNPPSE--SEGSDGR-FLISYDRTLVIKEVSSEDIADM 144
FR R+ FGI DYL SL P E S G+ G F +S D +IK V ++ +
Sbjct: 145 VAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKEAEFL 204
Query: 145 HSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGS 204
L Y+ + + + TLLP+F G+Y V ++ ++VM N+ + +H KYDLKGS
Sbjct: 205 QKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYDLKGS 263
Query: 205 LVSREASDKEKVKELPTLKDMDFLNK-NQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDY 263
R AS KE+ K LPT KD+DFL +++ + + L+RD L KIMDY
Sbjct: 264 TYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFKIMDY 323
Query: 264 SLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRP 323
SLL+ IH+I + A SE P Y T+ E I G R
Sbjct: 324 SLLMSIHNI-------DHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQG---EARR 373
Query: 324 LGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEIS 383
G E + + R+++G ++ + ++G+IDIL Y KK H+ K + H G +S
Sbjct: 374 GGTMETDDHMGGIPARNSKG--ERLLLYIGIIDILQSYRFVKKLEHSWKALVHD-GDTVS 430
Query: 384 TVHPEQYAKRFLDFITN 400
P YA+RF F+ N
Sbjct: 431 VHRPGFYAERFQRFMCN 447
>gi|208431776 phosphatidylinositol-4-phosphate 5-kinase, type I,
alpha isoform 4 [Homo sapiens]
Length = 500
Score = 156 bits (395), Expect = 3e-38
Identities = 119/377 (31%), Positives = 174/377 (46%), Gaps = 37/377 (9%)
Query: 47 LVGVFLWGVAHSINELSQVPPPVMLLPDDFKASS-------------------KIKEYCP 87
L G G+ H++ LS P +L+ D + S + K Y P
Sbjct: 72 LKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAP 131
Query: 88 QVFRNLRDRFGIDDQDYLVSLTRNPPSE--SEGSDGR-FLISYDRTLVIKEVSSEDIADM 144
FR R+ FGI DYL SL P E S G+ G F +S D +IK V ++ +
Sbjct: 132 VAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKEAEFL 191
Query: 145 HSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGS 204
L Y+ + + + TLLP+F G+Y V ++ ++VM N+ + +H KYDLKGS
Sbjct: 192 QKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYDLKGS 250
Query: 205 LVSREASDKEKVKELPTLKDMDFLNK-NQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDY 263
R AS KE+ K LPT KD+DFL +++ + + L+RD L KIMDY
Sbjct: 251 TYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFKIMDY 310
Query: 264 SLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRP 323
SLL+ IH+I + A SE P Y T+ E I G R
Sbjct: 311 SLLMSIHNI-------DHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQG---EARR 360
Query: 324 LGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEIS 383
G E + + R+++G ++ + ++G+IDIL Y KK H+ K + H G +S
Sbjct: 361 GGTMETDDHMGGIPARNSKG--ERLLLYIGIIDILQSYRFVKKLEHSWKALVHD-GDTVS 417
Query: 384 TVHPEQYAKRFLDFITN 400
P YA+RF F+ N
Sbjct: 418 VHRPGFYAERFQRFMCN 434
>gi|4505815 phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
isoform 2 [Homo sapiens]
Length = 549
Score = 156 bits (395), Expect = 3e-38
Identities = 119/377 (31%), Positives = 174/377 (46%), Gaps = 37/377 (9%)
Query: 47 LVGVFLWGVAHSINELSQVPPPVMLLPDDFKASS-------------------KIKEYCP 87
L G G+ H++ LS P +L+ D + S + K Y P
Sbjct: 72 LKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAP 131
Query: 88 QVFRNLRDRFGIDDQDYLVSLTRNPPSE--SEGSDGR-FLISYDRTLVIKEVSSEDIADM 144
FR R+ FGI DYL SL P E S G+ G F +S D +IK V ++ +
Sbjct: 132 VAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKEAEFL 191
Query: 145 HSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGS 204
L Y+ + + + TLLP+F G+Y V ++ ++VM N+ + +H KYDLKGS
Sbjct: 192 QKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYDLKGS 250
Query: 205 LVSREASDKEKVKELPTLKDMDFLNK-NQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDY 263
R AS KE+ K LPT KD+DFL +++ + + L+RD L KIMDY
Sbjct: 251 TYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFKIMDY 310
Query: 264 SLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRP 323
SLL+ IH+I + A SE P Y T+ E I G R
Sbjct: 311 SLLMSIHNI-------DHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQG---EARR 360
Query: 324 LGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEIS 383
G E + + R+++G ++ + ++G+IDIL Y KK H+ K + H G +S
Sbjct: 361 GGTMETDDHMGGIPARNSKG--ERLLLYIGIIDILQSYRFVKKLEHSWKALVHD-GDTVS 417
Query: 384 TVHPEQYAKRFLDFITN 400
P YA+RF F+ N
Sbjct: 418 VHRPGFYAERFQRFMCN 434
>gi|4505817 phosphatidylinositol-4-phosphate 5-kinase, type I, beta
isoform 2 [Homo sapiens]
Length = 540
Score = 154 bits (390), Expect = 1e-37
Identities = 124/414 (29%), Positives = 185/414 (44%), Gaps = 48/414 (11%)
Query: 12 SAATAGPG-PGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVM 70
SAA G PG KT KK A+ + G G+ +++ L+ P +
Sbjct: 3 SAAENGEAAPGKQNEEKTYKK----------TASSAIKGAIQLGIGYTVGNLTSKPERDV 52
Query: 71 LLPDDFKASS-------------------KIKEYCPQVFRNLRDRFGIDDQDYLVSLTRN 111
L+ D + S + K Y P FR R+ FGI DYL S+
Sbjct: 53 LMQDFYVVESVFLPSEGSNLTPAHHYPDFRFKTYAPLAFRYFRELFGIKPDDYLYSICSE 112
Query: 112 PPSE--SEGSDGR-FLISYDRTLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFL 168
P E + G+ G F ++ D +IK V ++ + L Y+ + + + TLLP+F
Sbjct: 113 PLIELSNPGASGSLFFVTSDDEFIIKTVQHKEAEFLQKLLPGYYMNLNQ-NPRTLLPKFY 171
Query: 169 GMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFL 228
G+Y + + ++VM N+ + +H YDLKGS R AS KE+ K PT KD+DFL
Sbjct: 172 GLYCMQSGGINIRIVVMNNVLPRSMRMHFTYDLKGSTYKRRASRKEREKSNPTFKDLDFL 231
Query: 229 -NKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRG-SEPEEEAPVRE 286
+ ++ +Y E ++ L+RD L KIMDYSLLLGIH + E EEE P
Sbjct: 232 QDMHEGLYFDTETYNALMKTLQRDCRVLESFKIMDYSLLLGIHFLDHSLKEKEEETPQNV 291
Query: 287 DESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQ 346
+++ G + A+ G G G + +G I + +
Sbjct: 292 PDAKRTGMQKVLYSTAMESIQGPGKSGDGIITENPDTMG-----------GIPAKSHRGE 340
Query: 347 KEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFITN 400
K + FMG+IDIL Y KK H+ K + + G +S P YA RFL F+ +
Sbjct: 341 KLLLFMGIIDILQSYRLMKKLEHSWKALVYD-GDTVSVHRPSFYADRFLKFMNS 393
>gi|208431774 phosphatidylinositol-4-phosphate 5-kinase, type I,
alpha isoform 3 [Homo sapiens]
Length = 522
Score = 131 bits (330), Expect = 9e-31
Identities = 111/377 (29%), Positives = 158/377 (41%), Gaps = 65/377 (17%)
Query: 47 LVGVFLWGVAHSINELSQVPPPVMLLPDDFKASS-------------------KIKEYCP 87
L G G+ H++ LS P +L+ D + S + K Y P
Sbjct: 73 LKGAIQLGITHTVGSLSTKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYNDFRFKTYAP 132
Query: 88 QVFRNLRDRFGIDDQDYLVSLTRNPPSE--SEGSDGR-FLISYDRTLVIKEVSSEDIADM 144
FR R+ FGI DYL SL P E S G+ G F +S D +IK V ++ +
Sbjct: 133 VAFRYFRELFGIRPDDYLYSLCSEPLIELCSSGASGSLFYVSSDDEFIIKTVQHKEAEFL 192
Query: 145 HSNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDNEDSYMLVMRNMFSHRLPVHRKYDLKGS 204
L Y+ + + + TLLP+F G+Y V ++ ++VM N+ + +H KYDLKGS
Sbjct: 193 QKLLPGYYMNLNQ-NPRTLLPKFYGLYCVQAGGKNIRIVVMNNLLPRSVKMHIKYDLKGS 251
Query: 205 LVSREASDKEKVKELPTLKDMDFLNK-NQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDY 263
R AS KE+ K LPT KD+DFL +++ + + L+RD L KIMDY
Sbjct: 252 TYKRRASQKEREKPLPTFKDLDFLQDIPDGLFLDADMYNALCKTLQRDCLVLQSFKIMDY 311
Query: 264 SLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRP 323
SLL+ IH+I + A SE P Y T+ E I G
Sbjct: 312 SLLMSIHNI-------DHAQREPLSSETQYSVDTRRPAPQKALYSTAMESIQG------- 357
Query: 324 LGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEIS 383
E G ++ Q+ KK H+ K + H G +S
Sbjct: 358 ------------------------EARRGGTMETDDQF--VKKLEHSWKALVHD-GDTVS 390
Query: 384 TVHPEQYAKRFLDFITN 400
P YA+RF F+ N
Sbjct: 391 VHRPGFYAERFQRFMCN 407
>gi|206725454 phosphatidylinositol-4-phosphate 5-kinase-like 1
isoform 1 [Homo sapiens]
Length = 394
Score = 99.0 bits (245), Expect = 7e-21
Identities = 84/315 (26%), Positives = 146/315 (46%), Gaps = 36/315 (11%)
Query: 90 FRNLRDRFGIDDQDYLVSLTRNPPS----ESEGSDGRFLISYDRTLVIKEVSSEDIADMH 145
F LR G+ ++DY +L P + S F +S+D+ +K ++ +
Sbjct: 105 FAWLRRSLGLAEEDYQAALGPGGPYLQFLSTSKSKASFFLSHDQRFFLKTQGRREVQALL 164
Query: 146 SNLSNYHQYIVKCHGNTLLPQFLGMYRVSVDN-EDSYMLVMRNMFSHRLPVHRKYDLKGS 204
++L Y Q++ + H ++LL + LG++ + VD + +Y +VM+++F + +YD+KG
Sbjct: 165 AHLPRYVQHLQR-HPHSLLARLLGVHSLRVDRGKKTYFIVMQSVFYPAGRISERYDIKGC 223
Query: 205 LVSREASDKEKVKELP-TLKDMDFLNKNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDY 263
VSR + L LKD++F K + +G + + FL +++ D FL +L ++DY
Sbjct: 224 EVSRWVDPAPEGSPLVLVLKDLNFQGKT--INLGPQ-RSWFLRQMELDTTFLRELNVLDY 280
Query: 264 SLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRP 323
SLL+ R E E SL A SPE P
Sbjct: 281 SLLIAFQ--------------RLHEDERGPGSSLIFRTARSVQGAQSPEESRAQNRRLLP 326
Query: 324 LGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHGAGAEIS 383
P A+ +G Q+ YF+G++D+ T Y +K+ H KT+++ G S
Sbjct: 327 DAPN---------ALHILDGPEQR--YFLGVVDLATVYGLRKRLEHLWKTLRY-PGRTFS 374
Query: 384 TVHPEQYAKRFLDFI 398
TV P +YA+R ++
Sbjct: 375 TVSPARYARRLCQWV 389
>gi|27735085 phosphatidylinositol-4-phosphate 5-kinase-like 1
isoform 2 [Homo sapiens]
Length = 191
Score = 65.5 bits (158), Expect = 8e-11
Identities = 59/215 (27%), Positives = 95/215 (44%), Gaps = 30/215 (13%)
Query: 185 MRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELP-TLKDMDFLNKNQKVYIGEEEKKI 243
M+++F + +YD+KG VSR + L LKD++F K + +G + +
Sbjct: 1 MQSVFYPAGRISERYDIKGCEVSRWVDPAPEGSPLVLVLKDLNFQGKT--INLGPQ-RSW 57
Query: 244 FLEKLKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPAL 303
FL +++ D FL +L ++DYSLL+ R E E SL A
Sbjct: 58 FLRQMELDTTFLRELNVLDYSLLIAFQ--------------RLHEDERGPGSSLIFRTAR 103
Query: 304 VGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGAPQKEVYFMGLIDILTQYDA 363
SPE P P A+ +G Q+ YF+G++D+ T Y
Sbjct: 104 SVQGAQSPEESRAQNRRLLPDAPN---------ALHILDGPEQR--YFLGVVDLATVYGL 152
Query: 364 KKKAAHAAKTVKHGAGAEISTVHPEQYAKRFLDFI 398
+K+ H KT+++ G STV P +YA+R ++
Sbjct: 153 RKRLEHLWKTLRY-PGRTFSTVSPARYARRLCQWV 186
>gi|121583483 phosphatidylinositol-3-phosphate 5-kinase type III
isoform 2 [Homo sapiens]
Length = 2098
Score = 63.9 bits (154), Expect = 2e-10
Identities = 60/222 (27%), Positives = 100/222 (45%), Gaps = 16/222 (7%)
Query: 65 VPPPVMLLPDDFKASSKIKEYCPQVFRNLRDRF-GIDDQDYLVSLTRNPPSESEG--SDG 121
+ P V L D A + Y F +R+ ++D++ SL+ + P ++ G S
Sbjct: 1805 INPHVELQFSDANAKFYCRLYYAGEFHKMREVILDSSEEDFIRSLSHSSPWQARGGKSGA 1864
Query: 122 RFLISYDRTLVIKEVSSEDIADMHSNLSNYHQYI---VKCHGNTLLPQFLGMYRVSVDNE 178
F + D ++K++ ++ +Y YI V+ T L + LG+YR+ N
Sbjct: 1865 AFYATEDDRFILKQMPRLEVQSFLDFAPHYFNYITNAVQQKRPTALAKILGVYRIGYKNS 1924
Query: 179 DSY------MLVMRNMFSHRLPVHRKYDLKGSLVSREA-SDKEKVKELPTLKDMDFLN-- 229
+ +LVM N+F R + + +DLKGSL +R +D K L D + L
Sbjct: 1925 QNNTEKKLDLLVMENLFYGR-KMAQVFDLKGSLRNRNVKTDTGKESCDVVLLDENLLKMV 1983
Query: 230 KNQKVYIGEEEKKIFLEKLKRDVEFLVQLKIMDYSLLLGIHD 271
++ +YI K + + D FL I+DYSLL+G D
Sbjct: 1984 RDNPLYIRSHSKAVLRTSIHSDSHFLSSHLIIDYSLLVGRDD 2025
>gi|148227842 Myb-like, SWIRM and MPN domains 1 [Homo sapiens]
Length = 828
Score = 35.0 bits (79), Expect = 0.12
Identities = 41/188 (21%), Positives = 78/188 (41%), Gaps = 31/188 (16%)
Query: 11 VSAATAGPGPGFGFASKTKKKHFVQQKVKVFRAADPLVGVFLWGVAHSINELSQVPPPVM 70
V+AA A PG G AS +K H++ + G+ W + ++I+E ++ M
Sbjct: 15 VAAAGAQPGSGENTASVLQKDHYLDSSWRTEN------GLIPWTLDNTISEENRAVIEKM 68
Query: 71 LLPDDFKASSKIKEYCPQVFRNLRDRFGIDDQDYLVSLTR------NPPSESEGSDGRFL 124
LL +++ S K + +V+ + ++ DD+ Y+ SL + + P++ ++
Sbjct: 69 LLEEEYYLSKKSQP--EKVWLDQKE----DDKKYMKSLQKTAKIMVHSPTKPASYSVKWT 122
Query: 125 ISYDR-------------TLVIKEVSSEDIADMHSNLSNYHQYIVKCHGNTLLPQFLGMY 171
I T + K + S + + S Y + VKC + P +
Sbjct: 123 IEEKELFEQGLAKFGRRWTKISKLIGSRTVLQVKSYARQYFKNKVKCGLDKETPNQKTGH 182
Query: 172 RVSVDNED 179
+ V NED
Sbjct: 183 NLQVKNED 190
>gi|6005997 double C2-like domains, beta [Homo sapiens]
Length = 412
Score = 32.7 bits (73), Expect = 0.60
Identities = 26/93 (27%), Positives = 36/93 (38%), Gaps = 17/93 (18%)
Query: 285 REDESEVDGDCSLTGPPALVGSYGTSPEGIGGYIHSHRPLGPGEFESFIDVYAIRSAEGA 344
RED+ +VD L G+YG+SP G + P P E E A+G
Sbjct: 77 REDDEDVD---------QLFGAYGSSPGPSPGPSPARPPAKPPEDEP--------DADGY 119
Query: 345 PQKEVYFMGLIDILTQYDAKKKAAHAAKTVKHG 377
+ +G +D YD + A H T G
Sbjct: 120 ESDDCTALGTLDFSLLYDQENNALHCTITKAKG 152
>gi|20149594 heat shock 90kDa protein 1, beta [Homo sapiens]
Length = 724
Score = 32.0 bits (71), Expect = 1.0
Identities = 29/81 (35%), Positives = 40/81 (49%), Gaps = 9/81 (11%)
Query: 163 LLPQFLGMYRVSVDNEDSYMLVMRNMF--SHRLPVHRKYDLKG--SLVSREASDKEKVKE 218
L+P++L R VD+ED + + R M S L V RK +K L S A DKE K
Sbjct: 369 LIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNIVKKCLELFSELAEDKENYK- 427
Query: 219 LPTLKDMDFLNKNQKVYIGEE 239
K + +KN K+ I E+
Sbjct: 428 ----KFYEAFSKNLKLGIHED 444
>gi|154146191 heat shock 90kDa protein 1, alpha isoform 2 [Homo
sapiens]
Length = 732
Score = 30.0 bits (66), Expect = 3.9
Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 9/83 (10%)
Query: 163 LLPQFLGMYRVSVDNEDSYMLVMRNMF--SHRLPVHRKYDLKG--SLVSREASDKEKVKE 218
L+P++L R VD+ED + + R M S L V RK +K L + A DKE K
Sbjct: 377 LIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYK- 435
Query: 219 LPTLKDMDFLNKNQKVYIGEEEK 241
K + +KN K+ I E+ +
Sbjct: 436 ----KFYEQFSKNIKLGIHEDSQ 454
>gi|153792590 heat shock 90kDa protein 1, alpha isoform 1 [Homo
sapiens]
Length = 854
Score = 30.0 bits (66), Expect = 3.9
Identities = 28/83 (33%), Positives = 41/83 (49%), Gaps = 9/83 (10%)
Query: 163 LLPQFLGMYRVSVDNEDSYMLVMRNMF--SHRLPVHRKYDLKG--SLVSREASDKEKVKE 218
L+P++L R VD+ED + + R M S L V RK +K L + A DKE K
Sbjct: 499 LIPEYLNFIRGVVDSEDLPLNISREMLQQSKILKVIRKNLVKKCLELFTELAEDKENYK- 557
Query: 219 LPTLKDMDFLNKNQKVYIGEEEK 241
K + +KN K+ I E+ +
Sbjct: 558 ----KFYEQFSKNIKLGIHEDSQ 576
>gi|154240677 hypothetical protein LOC399949 isoform 2 [Homo
sapiens]
Length = 169
Score = 30.0 bits (66), Expect = 3.9
Identities = 26/77 (33%), Positives = 37/77 (48%), Gaps = 5/77 (6%)
Query: 183 LVMRNMFSHRLPVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKK 242
LV+R S RLPV R +GS E S + L + K+ D + K+ EE+ K
Sbjct: 54 LVLRRDSSQRLPVARPRRSRGS----ENSHSSQSFHLASNKNRDIFAEALKIQESEEKVK 109
Query: 243 IFLEKLKRDVEFLVQLK 259
+L+K K E L L+
Sbjct: 110 -YLQKAKTREEILQLLR 125
>gi|117553613 coiled-coil domain containing 151 [Homo sapiens]
Length = 595
Score = 30.0 bits (66), Expect = 3.9
Identities = 17/60 (28%), Positives = 35/60 (58%), Gaps = 4/60 (6%)
Query: 231 NQKVYIGEEEKKIFLEK----LKRDVEFLVQLKIMDYSLLLGIHDIIRGSEPEEEAPVRE 286
++K+ + E ++K F E +K++ E + QL+ +L L + D+++G E +A +RE
Sbjct: 75 HKKIQLLEGDRKAFFESSQWNIKKNQETISQLRKETKALELKLLDLLKGDEKVVQAVIRE 134
>gi|50053795 eukaryotic translation initiation factor 4B [Homo
sapiens]
Length = 611
Score = 29.6 bits (65), Expect = 5.1
Identities = 16/41 (39%), Positives = 23/41 (56%), Gaps = 4/41 (9%)
Query: 276 SEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEGIGG 316
++P EE P R+DE++VDG + P G+ P G GG
Sbjct: 515 AQPSEEGPGRKDENKVDG---MNAPKGQTGNSSRGP-GDGG 551
>gi|4758220 XAP-5 protein [Homo sapiens]
Length = 339
Score = 29.3 bits (64), Expect = 6.6
Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 15/93 (16%)
Query: 209 EASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIF-----------LEKLKRDVEFLVQ 257
EA K L TL DM Q+ + E EK++ LEKL R+ E +
Sbjct: 57 EAELKSSTVGLVTLNDM---KAKQEALVKEREKQLAKKEQSKELQMKLEKL-REKERKKE 112
Query: 258 LKIMDYSLLLGIHDIIRGSEPEEEAPVREDESE 290
K SL + + G E EEEA + E+E E
Sbjct: 113 AKRKISSLSFTLEEEEEGGEEEEEAAMYEEEME 145
>gi|145580615 KRI1 homolog [Homo sapiens]
Length = 709
Score = 29.3 bits (64), Expect = 6.6
Identities = 15/45 (33%), Positives = 22/45 (48%)
Query: 269 IHDIIRGSEPEEEAPVREDESEVDGDCSLTGPPALVGSYGTSPEG 313
+ D I EEE EDE E++ + + GPP + +S EG
Sbjct: 246 LRDYILNKRYEEEEEEEEDEEEMEEEEGVHGPPVQLAVDDSSDEG 290
>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
Length = 556
Score = 29.3 bits (64), Expect = 6.6
Identities = 14/54 (25%), Positives = 28/54 (51%)
Query: 194 PVHRKYDLKGSLVSREASDKEKVKELPTLKDMDFLNKNQKVYIGEEEKKIFLEK 247
P + + S E+SD+E+ ++LP + + + +K Y G+ KK ++K
Sbjct: 126 PAKEENPRRASKAVEESSDEERQRDLPAQRGEESSEEEEKGYKGKTRKKPVVKK 179
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.136 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,507,396
Number of Sequences: 37866
Number of extensions: 776853
Number of successful extensions: 2581
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 2523
Number of HSP's gapped (non-prelim): 31
length of query: 403
length of database: 18,247,518
effective HSP length: 105
effective length of query: 298
effective length of database: 14,271,588
effective search space: 4252933224
effective search space used: 4252933224
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.