Search of human proteins with 226371618

Search of human proteins with 226371618

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|226371618 signal recognition particle 54kDa isoform 2 [Homo
sapiens]
         (455 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|226371618 signal recognition particle 54kDa isoform 2 [Homo s...   903   0.0  
gi|4507215 signal recognition particle 54kDa isoform 1 [Homo sap...   888   0.0  
gi|89061728 PREDICTED: similar to signal recognition particle 54...   323   3e-88
gi|23308697 signal recognition particle receptor [Homo sapiens]        89   1e-17
gi|73747915 transporter 2, ATP-binding cassette, sub-family B is...    34   0.24 
gi|73747917 transporter 2, ATP-binding cassette, sub-family B is...    33   0.41 
gi|38348356 testis expressed 9 [Homo sapiens]                          33   0.41 
gi|119943102 CREB binding protein isoform b [Homo sapiens]             31   2.0  
gi|119943104 CREB binding protein isoform a [Homo sapiens]             31   2.0  
gi|4502011 adenylate kinase 1 [Homo sapiens]                           30   5.9  
gi|18375673 regulator of nonsense transcripts 1 [Homo sapiens]         30   5.9  
gi|237858799 adenylate kinase domain containing 1 isoform 1 [Hom...    29   7.7  
gi|21450759 adenylate kinase domain containing 1 isoform 2 [Homo...    29   7.7  

>gi|226371618 signal recognition particle 54kDa isoform 2 [Homo
           sapiens]
          Length = 455

 Score =  903 bits (2334), Expect = 0.0
 Identities = 455/455 (100%), Positives = 455/455 (100%)

Query: 1   MPPLSMKRSAIDLEEMASGLNKRKMIQHAVFKELVKLVDPGVKAWTPTKGKQNVIMFVGL 60
           MPPLSMKRSAIDLEEMASGLNKRKMIQHAVFKELVKLVDPGVKAWTPTKGKQNVIMFVGL
Sbjct: 1   MPPLSMKRSAIDLEEMASGLNKRKMIQHAVFKELVKLVDPGVKAWTPTKGKQNVIMFVGL 60

Query: 61  QGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPV 120
           QGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPV
Sbjct: 61  QGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPV 120

Query: 121 IIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVANAIQPDNIVYVMDASIGQAC 180
           IIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVANAIQPDNIVYVMDASIGQAC
Sbjct: 121 IIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVANAIQPDNIVYVMDASIGQAC 180

Query: 181 EAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQP 240
           EAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQP
Sbjct: 181 EAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQP 240

Query: 241 FISKLLGMGDIEGLIDKVNELKLDDNEALIEKLKHGQFTLRDMYEQFQNIMKMGPFSQIL 300
           FISKLLGMGDIEGLIDKVNELKLDDNEALIEKLKHGQFTLRDMYEQFQNIMKMGPFSQIL
Sbjct: 241 FISKLLGMGDIEGLIDKVNELKLDDNEALIEKLKHGQFTLRDMYEQFQNIMKMGPFSQIL 300

Query: 301 GMIPGFGTDFMSKGNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKQPGRIQRVARG 360
           GMIPGFGTDFMSKGNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKQPGRIQRVARG
Sbjct: 301 GMIPGFGTDFMSKGNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKQPGRIQRVARG 360

Query: 361 SGVSTRDVQELLTQYTKFAQMVKKMGGIKGLFKGGDMSKNVSQSQMAKLNQQMAKMMDPR 420
           SGVSTRDVQELLTQYTKFAQMVKKMGGIKGLFKGGDMSKNVSQSQMAKLNQQMAKMMDPR
Sbjct: 361 SGVSTRDVQELLTQYTKFAQMVKKMGGIKGLFKGGDMSKNVSQSQMAKLNQQMAKMMDPR 420

Query: 421 VLHHMGGMAGLQSMMRQFQQGAAGNMKGMMGFNNM 455
           VLHHMGGMAGLQSMMRQFQQGAAGNMKGMMGFNNM
Sbjct: 421 VLHHMGGMAGLQSMMRQFQQGAAGNMKGMMGFNNM 455


>gi|4507215 signal recognition particle 54kDa isoform 1 [Homo
           sapiens]
          Length = 504

 Score =  888 bits (2294), Expect = 0.0
 Identities = 447/448 (99%), Positives = 448/448 (100%)

Query: 8   RSAIDLEEMASGLNKRKMIQHAVFKELVKLVDPGVKAWTPTKGKQNVIMFVGLQGSGKTT 67
           +SAIDLEEMASGLNKRKMIQHAVFKELVKLVDPGVKAWTPTKGKQNVIMFVGLQGSGKTT
Sbjct: 57  KSAIDLEEMASGLNKRKMIQHAVFKELVKLVDPGVKAWTPTKGKQNVIMFVGLQGSGKTT 116

Query: 68  TCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIASEGV 127
           TCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIASEGV
Sbjct: 117 TCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIASEGV 176

Query: 128 EKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVANAIQPDNIVYVMDASIGQACEAQAKAF 187
           EKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVANAIQPDNIVYVMDASIGQACEAQAKAF
Sbjct: 177 EKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVANAIQPDNIVYVMDASIGQACEAQAKAF 236

Query: 188 KDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLG 247
           KDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLG
Sbjct: 237 KDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLLG 296

Query: 248 MGDIEGLIDKVNELKLDDNEALIEKLKHGQFTLRDMYEQFQNIMKMGPFSQILGMIPGFG 307
           MGDIEGLIDKVNELKLDDNEALIEKLKHGQFTLRDMYEQFQNIMKMGPFSQILGMIPGFG
Sbjct: 297 MGDIEGLIDKVNELKLDDNEALIEKLKHGQFTLRDMYEQFQNIMKMGPFSQILGMIPGFG 356

Query: 308 TDFMSKGNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKQPGRIQRVARGSGVSTRD 367
           TDFMSKGNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKQPGRIQRVARGSGVSTRD
Sbjct: 357 TDFMSKGNEQESMARLKKLMTIMDSMNDQELDSTDGAKVFSKQPGRIQRVARGSGVSTRD 416

Query: 368 VQELLTQYTKFAQMVKKMGGIKGLFKGGDMSKNVSQSQMAKLNQQMAKMMDPRVLHHMGG 427
           VQELLTQYTKFAQMVKKMGGIKGLFKGGDMSKNVSQSQMAKLNQQMAKMMDPRVLHHMGG
Sbjct: 417 VQELLTQYTKFAQMVKKMGGIKGLFKGGDMSKNVSQSQMAKLNQQMAKMMDPRVLHHMGG 476

Query: 428 MAGLQSMMRQFQQGAAGNMKGMMGFNNM 455
           MAGLQSMMRQFQQGAAGNMKGMMGFNNM
Sbjct: 477 MAGLQSMMRQFQQGAAGNMKGMMGFNNM 504


>gi|89061728 PREDICTED: similar to signal recognition particle 54kDa
           [Homo sapiens]
          Length = 168

 Score =  323 bits (827), Expect = 3e-88
 Identities = 164/164 (100%), Positives = 164/164 (100%)

Query: 113 SYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVANAIQPDNIVYVM 172
           SYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVANAIQPDNIVYVM
Sbjct: 4   SYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVANAIQPDNIVYVM 63

Query: 173 DASIGQACEAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDD 232
           DASIGQACEAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDD
Sbjct: 64  DASIGQACEAQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDD 123

Query: 233 FEPFKTQPFISKLLGMGDIEGLIDKVNELKLDDNEALIEKLKHG 276
           FEPFKTQPFISKLLGMGDIEGLIDKVNELKLDDNEALIEKLKHG
Sbjct: 124 FEPFKTQPFISKLLGMGDIEGLIDKVNELKLDDNEALIEKLKHG 167


>gi|23308697 signal recognition particle receptor [Homo sapiens]
          Length = 638

 Score = 88.6 bits (218), Expect = 1e-17
 Identities = 53/217 (24%), Positives = 100/217 (46%), Gaps = 24/217 (11%)

Query: 54  VIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLK------------- 100
           V+ F G+ G GK+T  +K++++    G+   +   DTFRAGA +QL+             
Sbjct: 420 VVTFCGVNGVGKSTNLAKISFWLLENGFSVLIAACDTFRAGAVEQLRTHTRRLSALHPPE 479

Query: 101 QNATKARIPFYGSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVA 160
           ++  +  +  +      D   IA E +   +N+ F++++VDT+GR +    L   + ++ 
Sbjct: 480 KHGGRTMVQLFEKGYGKDAAGIAMEAIAFARNQGFDVVLVDTAGRMQDNAPLMTALAKLI 539

Query: 161 NAIQPDNIVYVMDASIGQACEAQAKAFKDKVD----------VASVIVTKLDG-HAKGGG 209
               PD +++V +A +G     Q   F   +           +  +++TK D    K G 
Sbjct: 540 TVNTPDLVLFVGEALVGNEAVDQLVKFNRALADHSMAQTPRLIDGIVLTKFDTIDDKVGA 599

Query: 210 ALSAVAATKSPIIFIGTGEHIDDFEPFKTQPFISKLL 246
           A+S    T  PI+F+GTG+   D      +  ++ L+
Sbjct: 600 AISMTYITSKPIVFVGTGQTYCDLRSLNAKAVVAALM 636


>gi|73747915 transporter 2, ATP-binding cassette, sub-family B
           isoform 1 [Homo sapiens]
          Length = 703

 Score = 34.3 bits (77), Expect = 0.24
 Identities = 38/176 (21%), Positives = 69/176 (39%), Gaps = 17/176 (9%)

Query: 40  PGVKAWTPTKGKQNVIMFVGLQGSGKTTTCSKLAYYYQRKG------------WKTCLIC 87
           P +K  T T     V   VG  GSGK+T  + L   YQ  G            ++ C + 
Sbjct: 484 PVLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQVLLDEKPISQYEHCYLH 543

Query: 88  ADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIASEG--VEKFKNENFEIIIVDTSGR 145
           +     G    L   + +  I +     E D V+ A++    + F  E    I  D   +
Sbjct: 544 SQVVSVGQEPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAHADDFIQEMEHGIYTDVGEK 603

Query: 146 HKQEDSLFEEMLQVANAIQPDNIVYVMD---ASIGQACEAQAKAFKDKVDVASVIV 198
             Q  +  ++ L +A A+  D  V ++D   +++   CE   + +  + D   +++
Sbjct: 604 GSQLAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWNSRGDRTVLVI 659


>gi|73747917 transporter 2, ATP-binding cassette, sub-family B
           isoform 2 [Homo sapiens]
          Length = 653

 Score = 33.5 bits (75), Expect = 0.41
 Identities = 40/163 (24%), Positives = 65/163 (39%), Gaps = 18/163 (11%)

Query: 40  PGVKAWTPTKGKQNVIMFVGLQGSGKTTTCSKLAYYYQRKG------------WKTCLIC 87
           P +K  T T     V   VG  GSGK+T  + L   YQ  G            ++ C + 
Sbjct: 484 PVLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQVLLDEKPISQYEHCYLH 543

Query: 88  ADTFRAGAFDQLKQNATKARIPFYGSYTEMDPVIIASEG--VEKFKNENFEIIIVDTSGR 145
           +     G    L   + +  I +     E D V+ A++    + F  E    I  D   +
Sbjct: 544 SQVVSVGQEPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAHADDFIQEMEHGIYTDVGEK 603

Query: 146 HKQEDSLFEEMLQVANAIQPDNIVYVMD---ASIGQACEAQAK 185
             Q  +  ++ L +A A+  D  V ++D   +++   CE QAK
Sbjct: 604 GSQLAAGQKQRLAIARALVRDPRVLILDEATSALDVQCE-QAK 645


>gi|38348356 testis expressed 9 [Homo sapiens]
          Length = 391

 Score = 33.5 bits (75), Expect = 0.41
 Identities = 53/254 (20%), Positives = 107/254 (42%), Gaps = 23/254 (9%)

Query: 182 AQAKAFKDKVDVASVIVTKLDGHAKGGGALSAVAATKSPIIFIGTGEHIDDFEPFKTQPF 241
           ++ K     +D  + +  KL    KG    S+V    S +         +DF  F     
Sbjct: 101 SETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTADDVAIPEDFSDFSLAKT 160

Query: 242 ISKLLGMGDIEGLIDKVNEL--KLDDNEALIEKLKHGQFTLRDMYEQFQNIM-----KMG 294
           ISK+ G  + EGL + ++++   + ++     +++  +  L  M E+  N++     K  
Sbjct: 161 ISKIEGQLEEEGLPEYIDDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKED 220

Query: 295 PFSQILGMIPGFGTDFMSKG---NEQESMARLKKLMTIMDSMN------DQELDSTDGAK 345
               +   +  F  DFM +    N Q+S  +++K  T+ +  N       Q+L S +  +
Sbjct: 221 EIQNLKSQVKNFEEDFMRQQRTINMQQS--QVEKYKTLFEEANKKYDGLQQQLSSVE-RE 277

Query: 346 VFSKQPGRIQRVARGSGVSTR-DVQELLTQYTKF-AQMVKKMGGIKGLFKGGDMSKNVSQ 403
           + +K+  R+Q+ A  S  +T   +   L +  K+  ++ K     K +         V +
Sbjct: 278 LENKR--RLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEHKKIEVLK 335

Query: 404 SQMAKLNQQMAKMM 417
           S+  KL +Q  ++M
Sbjct: 336 SENKKLEKQKGELM 349


>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 31.2 bits (69), Expect = 2.0
 Identities = 19/67 (28%), Positives = 30/67 (44%)

Query: 385  MGGIKGLFKGGDMSKNVSQSQMAKLNQQMAKMMDPRVLHHMGGMAGLQSMMRQFQQGAAG 444
            MGG+    +  ++        MA +N Q  +M+  ++L         Q   +Q QQG+AG
Sbjct: 2123 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG 2182

Query: 445  NMKGMMG 451
               GM G
Sbjct: 2183 MAGGMAG 2189


>gi|119943104 CREB binding protein isoform a [Homo sapiens]
          Length = 2442

 Score = 31.2 bits (69), Expect = 2.0
 Identities = 19/67 (28%), Positives = 30/67 (44%)

Query: 385  MGGIKGLFKGGDMSKNVSQSQMAKLNQQMAKMMDPRVLHHMGGMAGLQSMMRQFQQGAAG 444
            MGG+    +  ++        MA +N Q  +M+  ++L         Q   +Q QQG+AG
Sbjct: 2161 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG 2220

Query: 445  NMKGMMG 451
               GM G
Sbjct: 2221 MAGGMAG 2227


>gi|4502011 adenylate kinase 1 [Homo sapiens]
          Length = 194

 Score = 29.6 bits (65), Expect = 5.9
 Identities = 30/121 (24%), Positives = 47/121 (38%), Gaps = 9/121 (7%)

Query: 51  KQNVIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICADTFRAGAFDQLKQNATKARIPF 110
           K  +I  VG  GSGK T C K+    Q+ G+ T L   D  R+       +    + I  
Sbjct: 7   KTKIIFVVGGPGSGKGTQCEKIV---QKYGY-THLSTGDLLRSEVSSGSARGKKLSEIME 62

Query: 111 YGSYTEMDPVIIASEGVEKFKNENFEIIIVDTSGRHKQEDSLFEEMLQVANAIQPDNIVY 170
            G    ++ V+         K    +  ++D   R  Q+   FE  +      QP  ++Y
Sbjct: 63  KGQLVPLETVLDMLRDAMVAKVNTSKGFLIDGYPREVQQGEEFERRIG-----QPTLLLY 117

Query: 171 V 171
           V
Sbjct: 118 V 118


>gi|18375673 regulator of nonsense transcripts 1 [Homo sapiens]
          Length = 1118

 Score = 29.6 bits (65), Expect = 5.9
 Identities = 26/99 (26%), Positives = 44/99 (44%), Gaps = 18/99 (18%)

Query: 5   SMKRSAIDLEEMASGLNKRKMIQHAVFKELVKLVDPGVKAWTP---------------TK 49
           ++K  A+D E   SG    K++ H V   ++K   P  K +T                T 
Sbjct: 426 ALKTFAVD-ETSVSGYIYHKLLGHEVEDVIIKCQLP--KRFTAQGLPDLNHSQVYAVKTV 482

Query: 50  GKQNVIMFVGLQGSGKTTTCSKLAYYYQRKGWKTCLICA 88
            ++ + +  G  G+GKT T + + Y+  R+G    L+CA
Sbjct: 483 LQRPLSLIQGPPGTGKTVTSATIVYHLARQGNGPVLVCA 521


>gi|237858799 adenylate kinase domain containing 1 isoform 1 [Homo
           sapiens]
          Length = 1911

 Score = 29.3 bits (64), Expect = 7.7
 Identities = 16/43 (37%), Positives = 22/43 (51%)

Query: 37  LVDPGVKAWTPTKGKQNVIMFVGLQGSGKTTTCSKLAYYYQRK 79
           L++P      P  G    +  +G Q SGKTT C+ LA  Y+ K
Sbjct: 376 LLNPRPYLLPPMPGPPCKVFILGPQYSGKTTLCNMLAENYKGK 418


>gi|21450759 adenylate kinase domain containing 1 isoform 2 [Homo
           sapiens]
          Length = 421

 Score = 29.3 bits (64), Expect = 7.7
 Identities = 16/43 (37%), Positives = 22/43 (51%)

Query: 37  LVDPGVKAWTPTKGKQNVIMFVGLQGSGKTTTCSKLAYYYQRK 79
           L++P      P  G    +  +G Q SGKTT C+ LA  Y+ K
Sbjct: 376 LLNPRPYLLPPMPGPPCKVFILGPQYSGKTTLCNMLAENYKGK 418


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.379 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,430,772
Number of Sequences: 37866
Number of extensions: 630750
Number of successful extensions: 1676
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1664
Number of HSP's gapped (non-prelim): 15
length of query: 455
length of database: 18,247,518
effective HSP length: 106
effective length of query: 349
effective length of database: 14,233,722
effective search space: 4967568978
effective search space used: 4967568978
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.