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Search of human proteins with 225690532
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|225690532 golgin, RAB6-interacting isoform b [Homo sapiens]
(246 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|225690529 golgin, RAB6-interacting isoform a [Homo sapiens] 493 e-140
gi|225690532 golgin, RAB6-interacting isoform b [Homo sapiens] 493 e-140
gi|13259510 dynactin 1 isoform 1 [Homo sapiens] 45 8e-05
gi|205277396 dynactin 1 isoform 4 [Homo sapiens] 44 2e-04
gi|205277392 dynactin 1 isoform 3 [Homo sapiens] 44 2e-04
gi|13259508 dynactin 1 isoform 2 [Homo sapiens] 44 2e-04
gi|148746195 trichohyalin [Homo sapiens] 40 0.002
gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithora... 40 0.002
gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithora... 40 0.002
gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithora... 40 0.002
gi|6912482 leucine zipper-EF-hand containing transmembrane prote... 39 0.005
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ... 38 0.009
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 38 0.009
gi|221139761 zinc finger protein 853 [Homo sapiens] 37 0.016
gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo sa... 36 0.027
gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sap... 36 0.027
gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo... 36 0.035
gi|20127519 TPX2, microtubule-associated protein homolog [Homo s... 36 0.035
gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens] 36 0.035
gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens] 36 0.035
gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens] 36 0.035
gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens] 36 0.035
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 35 0.046
gi|55749678 ninein-like [Homo sapiens] 35 0.046
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 35 0.046
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 35 0.046
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 35 0.046
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 35 0.046
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 35 0.046
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 35 0.046
>gi|225690529 golgin, RAB6-interacting isoform a [Homo sapiens]
Length = 394
Score = 493 bits (1270), Expect = e-140
Identities = 246/246 (100%), Positives = 246/246 (100%)
Query: 1 MSWAAVLAVAAARFGHFWGCRWPGPMAQGWAGFSEEELRRLKQTKDPFEPQRRLPAKKSR 60
MSWAAVLAVAAARFGHFWGCRWPGPMAQGWAGFSEEELRRLKQTKDPFEPQRRLPAKKSR
Sbjct: 1 MSWAAVLAVAAARFGHFWGCRWPGPMAQGWAGFSEEELRRLKQTKDPFEPQRRLPAKKSR 60
Query: 61 QQLQREKALVEQSQKLGLQDGSTSLLPEQLLSAPKQRVNVQKPPFSSPTLPSHFTLTSPV 120
QQLQREKALVEQSQKLGLQDGSTSLLPEQLLSAPKQRVNVQKPPFSSPTLPSHFTLTSPV
Sbjct: 61 QQLQREKALVEQSQKLGLQDGSTSLLPEQLLSAPKQRVNVQKPPFSSPTLPSHFTLTSPV 120
Query: 121 GDGQPQGIESQPKELGLENSHDGHNNVEILPPKPDCKLEKKKVELQEKSRWEVLQQEQRL 180
GDGQPQGIESQPKELGLENSHDGHNNVEILPPKPDCKLEKKKVELQEKSRWEVLQQEQRL
Sbjct: 121 GDGQPQGIESQPKELGLENSHDGHNNVEILPPKPDCKLEKKKVELQEKSRWEVLQQEQRL 180
Query: 181 MEEKNKRKKALLAKAIAERSKRTQAETMKLKRIQKELQALDDMVSADIGILRNRIDQASL 240
MEEKNKRKKALLAKAIAERSKRTQAETMKLKRIQKELQALDDMVSADIGILRNRIDQASL
Sbjct: 181 MEEKNKRKKALLAKAIAERSKRTQAETMKLKRIQKELQALDDMVSADIGILRNRIDQASL 240
Query: 241 DYSYAR 246
DYSYAR
Sbjct: 241 DYSYAR 246
>gi|225690532 golgin, RAB6-interacting isoform b [Homo sapiens]
Length = 246
Score = 493 bits (1270), Expect = e-140
Identities = 246/246 (100%), Positives = 246/246 (100%)
Query: 1 MSWAAVLAVAAARFGHFWGCRWPGPMAQGWAGFSEEELRRLKQTKDPFEPQRRLPAKKSR 60
MSWAAVLAVAAARFGHFWGCRWPGPMAQGWAGFSEEELRRLKQTKDPFEPQRRLPAKKSR
Sbjct: 1 MSWAAVLAVAAARFGHFWGCRWPGPMAQGWAGFSEEELRRLKQTKDPFEPQRRLPAKKSR 60
Query: 61 QQLQREKALVEQSQKLGLQDGSTSLLPEQLLSAPKQRVNVQKPPFSSPTLPSHFTLTSPV 120
QQLQREKALVEQSQKLGLQDGSTSLLPEQLLSAPKQRVNVQKPPFSSPTLPSHFTLTSPV
Sbjct: 61 QQLQREKALVEQSQKLGLQDGSTSLLPEQLLSAPKQRVNVQKPPFSSPTLPSHFTLTSPV 120
Query: 121 GDGQPQGIESQPKELGLENSHDGHNNVEILPPKPDCKLEKKKVELQEKSRWEVLQQEQRL 180
GDGQPQGIESQPKELGLENSHDGHNNVEILPPKPDCKLEKKKVELQEKSRWEVLQQEQRL
Sbjct: 121 GDGQPQGIESQPKELGLENSHDGHNNVEILPPKPDCKLEKKKVELQEKSRWEVLQQEQRL 180
Query: 181 MEEKNKRKKALLAKAIAERSKRTQAETMKLKRIQKELQALDDMVSADIGILRNRIDQASL 240
MEEKNKRKKALLAKAIAERSKRTQAETMKLKRIQKELQALDDMVSADIGILRNRIDQASL
Sbjct: 181 MEEKNKRKKALLAKAIAERSKRTQAETMKLKRIQKELQALDDMVSADIGILRNRIDQASL 240
Query: 241 DYSYAR 246
DYSYAR
Sbjct: 241 DYSYAR 246
>gi|13259510 dynactin 1 isoform 1 [Homo sapiens]
Length = 1278
Score = 44.7 bits (104), Expect = 8e-05
Identities = 56/220 (25%), Positives = 93/220 (42%), Gaps = 26/220 (11%)
Query: 37 ELRRLKQTKDPFEPQRRLPAKKSRQQLQREKALVEQSQKLGLQDGSTSL--LPEQLLSAP 94
+LR LK K P R+ ++ + + S LG GS S L S P
Sbjct: 130 KLRGLKPKKAP--TARKTTTRRPKPTRPASTGVAGASSSLG-PSGSASAGELSSSEPSTP 186
Query: 95 KQRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQPKELGLENSHDGHNNVEILPPKP 154
Q P ++P +P+ LTSP G P S+ +E D +E L K
Sbjct: 187 AQT------PLAAPIIPTP-VLTSP-GAVPPLPSPSKEEEGLRAQVRDLEEKLETLRLKR 238
Query: 155 D------CKLEKKKVELQEKSRWEVLQQEQ------RLMEEKNKRKKALLAKAIAERSKR 202
+LEK K++L++ W+ QEQ RL E + + K+AL AK
Sbjct: 239 AEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRLKEARKEAKEALEAKERYMEEMA 298
Query: 203 TQAETMKLKRIQKEL-QALDDMVSADIGILRNRIDQASLD 241
A+ +++ + KE+ + + + ++ L+ R+D+ + D
Sbjct: 299 DTADAIEMATLDKEMAEERAESLQQEVEALKERVDELTTD 338
>gi|205277396 dynactin 1 isoform 4 [Homo sapiens]
Length = 1139
Score = 43.5 bits (101), Expect = 2e-04
Identities = 46/182 (25%), Positives = 82/182 (45%), Gaps = 19/182 (10%)
Query: 77 GLQDGSTSLLPEQLLSAPK----QRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQP 132
G+ S+SL P SA + + + P ++P +P+ LTSP G P S+
Sbjct: 25 GVAGASSSLGPSGSASAGELSSSEPSTPAQTPLAAPIIPTP-VLTSP-GAVPPLPSPSKE 82
Query: 133 KELGLENSHDGHNNVEILPPKPD------CKLEKKKVELQEKSRWEVLQQEQ------RL 180
+E D +E L K +LEK K++L++ W+ QEQ RL
Sbjct: 83 EEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRL 142
Query: 181 MEEKNKRKKALLAKAIAERSKRTQAETMKLKRIQKEL-QALDDMVSADIGILRNRIDQAS 239
E + + K+AL AK A+ +++ + KE+ + + + ++ L+ R+D+ +
Sbjct: 143 KEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELT 202
Query: 240 LD 241
D
Sbjct: 203 TD 204
>gi|205277392 dynactin 1 isoform 3 [Homo sapiens]
Length = 1253
Score = 43.5 bits (101), Expect = 2e-04
Identities = 46/182 (25%), Positives = 82/182 (45%), Gaps = 19/182 (10%)
Query: 77 GLQDGSTSLLPEQLLSAPK----QRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQP 132
G+ S+SL P SA + + + P ++P +P+ LTSP G P S+
Sbjct: 139 GVAGASSSLGPSGSASAGELSSSEPSTPAQTPLAAPIIPTP-VLTSP-GAVPPLPSPSKE 196
Query: 133 KELGLENSHDGHNNVEILPPKPD------CKLEKKKVELQEKSRWEVLQQEQ------RL 180
+E D +E L K +LEK K++L++ W+ QEQ RL
Sbjct: 197 EEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRL 256
Query: 181 MEEKNKRKKALLAKAIAERSKRTQAETMKLKRIQKEL-QALDDMVSADIGILRNRIDQAS 239
E + + K+AL AK A+ +++ + KE+ + + + ++ L+ R+D+ +
Sbjct: 257 KEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELT 316
Query: 240 LD 241
D
Sbjct: 317 TD 318
>gi|13259508 dynactin 1 isoform 2 [Homo sapiens]
Length = 1144
Score = 43.5 bits (101), Expect = 2e-04
Identities = 46/182 (25%), Positives = 82/182 (45%), Gaps = 19/182 (10%)
Query: 77 GLQDGSTSLLPEQLLSAPK----QRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQP 132
G+ S+SL P SA + + + P ++P +P+ LTSP G P S+
Sbjct: 25 GVAGASSSLGPSGSASAGELSSSEPSTPAQTPLAAPIIPTP-VLTSP-GAVPPLPSPSKE 82
Query: 133 KELGLENSHDGHNNVEILPPKPD------CKLEKKKVELQEKSRWEVLQQEQ------RL 180
+E D +E L K +LEK K++L++ W+ QEQ RL
Sbjct: 83 EEGLRAQVRDLEEKLETLRLKRAEDKAKLKELEKHKIQLEQVQEWKSKMQEQQADLQRRL 142
Query: 181 MEEKNKRKKALLAKAIAERSKRTQAETMKLKRIQKEL-QALDDMVSADIGILRNRIDQAS 239
E + + K+AL AK A+ +++ + KE+ + + + ++ L+ R+D+ +
Sbjct: 143 KEARKEAKEALEAKERYMEEMADTADAIEMATLDKEMAEERAESLQQEVEALKERVDELT 202
Query: 240 LD 241
D
Sbjct: 203 TD 204
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 40.0 bits (92), Expect = 0.002
Identities = 42/191 (21%), Positives = 80/191 (41%), Gaps = 9/191 (4%)
Query: 35 EEELRRLKQTKDPFEPQRRLPAKKSRQQLQREKALVEQSQKLGLQDGSTSLLPEQ-LLSA 93
EE+L R ++ K + R KK Q + E+ L E+ +K LQ+ E+ L
Sbjct: 1000 EEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQE 1059
Query: 94 PKQRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQP-------KELGLENSHDGHNN 146
+Q + ++ L + + + Q + +P +E +
Sbjct: 1060 EEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQE 1119
Query: 147 VEILPPKPDCKLEKKKVELQEKSRWEVLQQEQRLM-EEKNKRKKALLAKAIAERSKRTQA 205
E L + K ++++E Q + EV Q+E++L+ EE KR++ L + E + Q
Sbjct: 1120 EEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQE 1179
Query: 206 ETMKLKRIQKE 216
E L+ Q++
Sbjct: 1180 EEQLLREEQEK 1190
Score = 36.2 bits (82), Expect = 0.027
Identities = 35/174 (20%), Positives = 82/174 (47%), Gaps = 9/174 (5%)
Query: 35 EEELRRLKQTKDPFEPQRRLPAKKSRQQLQREKALVEQSQK--LGLQDGSTSLLPEQLLS 92
E++LRR ++ + + +++L ++ ++ + E+ L +++++ L Q+ +L E+ L
Sbjct: 1697 EQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLR 1756
Query: 93 APKQRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQPKELGLENSHDGHNNVEILPP 152
++ +++ L + Q + ES K E ++ P
Sbjct: 1757 PEREEQQLRRQE-RDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQ 1815
Query: 153 KPDCKLEKKKVELQEKSRWEVLQQEQRLMEEKNKRKKALLAKAIAERSKRTQAE 206
+ D K ++ +LQ + +QEQRL +E++++ +A A E+S+R + E
Sbjct: 1816 QRDGKYRWEEEQLQLE------EQEQRLRQERDRQYRAEEQFATQEKSRREEQE 1863
Score = 32.3 bits (72), Expect = 0.39
Identities = 39/201 (19%), Positives = 87/201 (43%), Gaps = 16/201 (7%)
Query: 33 FSEEELRRLKQTKDPFEPQRRLPAKKSRQQLQR-EKALVEQSQKLGLQDGSTSLLPEQLL 91
F EE + ++ + E ++ L + +QLQR E+A Q ++ GLQ+ ++
Sbjct: 810 FLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQR 869
Query: 92 SAPKQRVNVQKPP-------FSSPTLPSHFTLTSPVGDGQPQGIESQPKELGLENSHDGH 144
K R +++ ++ P L + Q ++ + +EL E
Sbjct: 870 RDQKWRWQLEEERKRRRHTLYAKPALQEQLRK-------EQQLLQEEEEELQREEREKRR 922
Query: 145 NNVEILPPKPDCKLEKKKVELQEKSRWEVLQQEQRLMEEKNKRKKALLAKAIAER-SKRT 203
+ + + +L++++ +L + R + +QE+ K+K+ + + + E KR
Sbjct: 923 RQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRR 982
Query: 204 QAETMKLKRIQKELQALDDMV 224
+ E K R ++ELQ ++ +
Sbjct: 983 RQEREKKYREEEELQQEEEQL 1003
Score = 31.6 bits (70), Expect = 0.66
Identities = 35/182 (19%), Positives = 82/182 (45%), Gaps = 4/182 (2%)
Query: 35 EEELRRLKQTKDPFEPQRRLPAKKSRQQLQREKALVEQSQKLGLQDGSTSLLPEQLLSAP 94
E++LRR ++ + + +R ++ QQL+RE+ + Q+L + L EQ L
Sbjct: 336 EQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQ---QLRREQQLRR- 391
Query: 95 KQRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQPKELGLENSHDGHNNVEILPPKP 154
+Q++ ++ L L + Q + + +E E H+ + L +
Sbjct: 392 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQ 451
Query: 155 DCKLEKKKVELQEKSRWEVLQQEQRLMEEKNKRKKALLAKAIAERSKRTQAETMKLKRIQ 214
+ + + K E + + + +++Q +++ +R++ L ER ++ + +L+R Q
Sbjct: 452 EERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQ 511
Query: 215 KE 216
+E
Sbjct: 512 EE 513
Score = 31.6 bits (70), Expect = 0.66
Identities = 36/194 (18%), Positives = 87/194 (44%), Gaps = 32/194 (16%)
Query: 35 EEELRRLKQTKDPFEPQRRLPAKKSRQQLQREKALVEQSQKLGLQDGSTSLLPEQLLSAP 94
E+++RR +Q + E +++L ++ +QQL++E+ + + LQ+ +QL
Sbjct: 1585 EQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQERE----EQQLHRQE 1640
Query: 95 KQRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQPKELGLENSHDG--HNNVEILPP 152
+ R +++ P + Q +E L + D ++L
Sbjct: 1641 RDRKFLEEEP----------------------QLRRQEREQQLRHDRDRKFREEEQLLQE 1678
Query: 153 KPDCKLEKKKVELQEKSRWEVLQQEQR----LMEEKNKRKKALLAKAIAERSKRTQAETM 208
+ +L +++ + + + + L++++R L EE+ R++ L K E R + E
Sbjct: 1679 GEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQE 1738
Query: 209 KLKRIQKELQALDD 222
+L+R ++ + L++
Sbjct: 1739 QLRRQERYRKILEE 1752
Score = 31.2 bits (69), Expect = 0.86
Identities = 42/189 (22%), Positives = 76/189 (40%), Gaps = 13/189 (6%)
Query: 36 EELRRLKQTKDPFEPQRRLPAKKSRQQLQREKALVEQSQKLGLQDGSTSLLPEQLLSAPK 95
E+ RL+Q E +R ++ Q+L+RE+ E+ Q+L + +QL +
Sbjct: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQ 652
Query: 96 QRVNVQ-KPPFSSPTLPSHFTLTSPVGDGQPQGIESQPKELGLENSHDGHNNVEILPPKP 154
+R + K L + E + +EL E ++ PK
Sbjct: 653 ERREQRLKREEEEERLEQRLK--------REHEEERREQELAEEEQEQARERIKSRIPKW 704
Query: 155 DCKLEKKKVELQEK----SRWEVLQQEQRLMEEKNKRKKALLAKAIAERSKRTQAETMKL 210
+LE + Q K R + Q+ ++ EEK +R+++ L ER+ R Q E +
Sbjct: 705 QWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQR 764
Query: 211 KRIQKELQA 219
+ + QA
Sbjct: 765 RDFTWQWQA 773
Score = 30.0 bits (66), Expect = 1.9
Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 2/60 (3%)
Query: 161 KKVELQE--KSRWEVLQQEQRLMEEKNKRKKALLAKAIAERSKRTQAETMKLKRIQKELQ 218
+K+E QE + R E QQ+QRL E+ R+K + + +R Q E + + ++E Q
Sbjct: 279 RKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQ 338
Score = 30.0 bits (66), Expect = 1.9
Identities = 39/201 (19%), Positives = 93/201 (46%), Gaps = 32/201 (15%)
Query: 38 LRRLKQTKDPFEPQRRLPAKKSRQQLQREKAL-VEQSQKLGLQDGSTSLLPEQLLSAPKQ 96
L+R ++T+ + +R+ K+ +++ +RE+ L +E+ ++ Q+ L + +Q
Sbjct: 458 LKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQ 517
Query: 97 RVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQPKELGLENSHDGHNNVEILPPKPDC 156
R+ Q+ + Q + S+ ++L E ++L + +
Sbjct: 518 RLKRQEEE-----------------ERLQQRLRSE-QQLRREQEE---RREQLLKREEEK 556
Query: 157 KLEKKKVEL-----QEKSRWEVLQQE-----QRLMEEKNKRKKALLAKAIAERSKRTQAE 206
+LE+++ E QE+ R ++L++E QRL E+ +R + L + ER ++ +
Sbjct: 557 RLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERR 616
Query: 207 TMKLKRIQKELQALDDMVSAD 227
+LKR + E + ++ ++
Sbjct: 617 EQRLKREEPEEERRQQLLKSE 637
Score = 28.5 bits (62), Expect = 5.6
Identities = 17/68 (25%), Positives = 34/68 (50%), Gaps = 3/68 (4%)
Query: 33 FSEEELRRLKQTKDPFEPQRRLPAKKSRQQL---QREKALVEQSQKLGLQDGSTSLLPEQ 89
F EEE + ++ F + +L ++ QQL +R++ +E+ Q+L Q+ ++
Sbjct: 1448 FLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQE 1507
Query: 90 LLSAPKQR 97
L S +R
Sbjct: 1508 LRSQEPER 1515
>gi|90819237 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 1 [Homo
sapiens]
Length = 1834
Score = 39.7 bits (91), Expect = 0.002
Identities = 48/201 (23%), Positives = 92/201 (45%), Gaps = 11/201 (5%)
Query: 23 PGPMAQGWAGFSEEELRRLKQTKDPFEPQRRLPAKKSRQQLQREKALVEQSQKLGLQDGS 82
P P + G ++ ++ K E QR +K+R + +RE+ EQ +KLG Q +
Sbjct: 1388 PPPPSANQIGLPSAQVAAAERRKRE-EHQRWYEKEKARLEEERERKRREQERKLG-QMRT 1445
Query: 83 TSLLPEQLLSAPKQRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQPKELGLENSHD 142
SL P Q++ +KP S+ P + QP+ IE + + + S +
Sbjct: 1446 QSLNPAPFSPLTAQQMKPEKP--STLQRPQETVIRELQPQQQPRTIERRDLQY-ITVSKE 1502
Query: 143 GHNNVEILPPKPDCKLEKKKVELQEKSR-WEVLQQEQRLMEEKNKRKKALLAKAIAERSK 201
++ + L P P + K+K+E Q++ ++L +E + ++ K R + ++R +
Sbjct: 1503 ELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDR-----SAEESDRLR 1557
Query: 202 RTQAETMKLKRIQKELQALDD 222
+ E KR+Q+ Q +D
Sbjct: 1558 KLMLEWQFQKRLQESKQKDED 1578
>gi|90819233 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 2 [Homo
sapiens]
Length = 1651
Score = 39.7 bits (91), Expect = 0.002
Identities = 48/201 (23%), Positives = 92/201 (45%), Gaps = 11/201 (5%)
Query: 23 PGPMAQGWAGFSEEELRRLKQTKDPFEPQRRLPAKKSRQQLQREKALVEQSQKLGLQDGS 82
P P + G ++ ++ K E QR +K+R + +RE+ EQ +KLG Q +
Sbjct: 1389 PPPPSANQIGLPSAQVAAAERRKRE-EHQRWYEKEKARLEEERERKRREQERKLG-QMRT 1446
Query: 83 TSLLPEQLLSAPKQRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQPKELGLENSHD 142
SL P Q++ +KP S+ P + QP+ IE + + + S +
Sbjct: 1447 QSLNPAPFSPLTAQQMKPEKP--STLQRPQETVIRELQPQQQPRTIERRDLQY-ITVSKE 1503
Query: 143 GHNNVEILPPKPDCKLEKKKVELQEKSR-WEVLQQEQRLMEEKNKRKKALLAKAIAERSK 201
++ + L P P + K+K+E Q++ ++L +E + ++ K R + ++R +
Sbjct: 1504 ELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDR-----SAEESDRLR 1558
Query: 202 RTQAETMKLKRIQKELQALDD 222
+ E KR+Q+ Q +D
Sbjct: 1559 KLMLEWQFQKRLQESKQKDED 1579
Score = 27.7 bits (60), Expect = 9.5
Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 10/78 (12%)
Query: 145 NNVEILPPKPDCKLEKKKVELQEKSRWEVLQQEQRLM-----EEKNKRKKALLAKAIAER 199
N + +PPK K + E QEK V+Q +R + +EK KR+K L +A +
Sbjct: 130 NENDAIPPK---KAQSNGPEKQEKEG--VIQNFKRTLSKKEKKEKKKREKEALRQASDKD 184
Query: 200 SKRTQAETMKLKRIQKEL 217
+ Q E ++ R+ E+
Sbjct: 185 DRPFQGEDVENSRLAAEV 202
>gi|90819231 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 4 isoform 3 [Homo
sapiens]
Length = 1612
Score = 39.7 bits (91), Expect = 0.002
Identities = 48/201 (23%), Positives = 92/201 (45%), Gaps = 11/201 (5%)
Query: 23 PGPMAQGWAGFSEEELRRLKQTKDPFEPQRRLPAKKSRQQLQREKALVEQSQKLGLQDGS 82
P P + G ++ ++ K E QR +K+R + +RE+ EQ +KLG Q +
Sbjct: 1373 PPPPSANQIGLPSAQVAAAERRKRE-EHQRWYEKEKARLEEERERKRREQERKLG-QMRT 1430
Query: 83 TSLLPEQLLSAPKQRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQPKELGLENSHD 142
SL P Q++ +KP S+ P + QP+ IE + + + S +
Sbjct: 1431 QSLNPAPFSPLTAQQMKPEKP--STLQRPQETVIRELQPQQQPRTIERRDLQY-ITVSKE 1487
Query: 143 GHNNVEILPPKPDCKLEKKKVELQEKSR-WEVLQQEQRLMEEKNKRKKALLAKAIAERSK 201
++ + L P P + K+K+E Q++ ++L +E + ++ K R + ++R +
Sbjct: 1488 ELSSGDSLSPDPWKRDAKEKLEKQQQMHIVDMLSKEIQELQSKPDR-----SAEESDRLR 1542
Query: 202 RTQAETMKLKRIQKELQALDD 222
+ E KR+Q+ Q +D
Sbjct: 1543 KLMLEWQFQKRLQESKQKDED 1563
>gi|6912482 leucine zipper-EF-hand containing transmembrane protein
1 [Homo sapiens]
Length = 739
Score = 38.5 bits (88), Expect = 0.005
Identities = 41/172 (23%), Positives = 75/172 (43%), Gaps = 16/172 (9%)
Query: 58 KSRQQLQREKALVEQSQKLGLQDGST---SLLPEQLLSAPKQRVNVQKPPFSSPTLPSHF 114
K LQ E A+ ++ ++ LQ S PE++++AP QR + P T+
Sbjct: 465 KLEATLQEEAAIQQEHREKELQKRSEVAKDFEPERVVAAP-QRPGTEPQPEMPDTVLQSE 523
Query: 115 TLTSPVGDGQPQGIESQPKELGLENSHDGHNNVEILPPKPDCKLEKKKVELQEKSRWEVL 174
TL ++ P GL+ ++IL E+KK +EK E+L
Sbjct: 524 TLK-----------DTAPVLEGLKEEEITKEEIDILSDACSKLQEQKKSLTKEKEELELL 572
Query: 175 QQE-QRLMEEKNKRKKALLAKAIAERSKRTQAETMKLKRIQKELQALDDMVS 225
+++ Q E+ + KK L + + ++A KR+Q+ + +D ++S
Sbjct: 573 KEDVQDYSEDLQEIKKELSKTGEEKYVEESKASKRLTKRVQQMIGQIDGLIS 624
>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
isoform 2 [Homo sapiens]
Length = 1153
Score = 37.7 bits (86), Expect = 0.009
Identities = 49/195 (25%), Positives = 81/195 (41%), Gaps = 21/195 (10%)
Query: 23 PG-PMAQGWAGFSEEELRRLKQTKDPFEPQRRLPAKKSRQQLQREKALVEQSQK----LG 77
PG PM+ + EE R K KD +R+ KK ++ R +L +S +
Sbjct: 716 PGLPMSDQYVKLEEERRHRQKLEKDKRRKKRKEKEKKGKR---RHSSLPTESDEDIAPAQ 772
Query: 78 LQDGSTSLLPEQLLSAPKQRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQPKELGL 137
D T +PE L + + K P + P L P+ D + I+ K
Sbjct: 773 QVDIVTEEMPENALPSDED----DKDP-NDPYRALDIDLDKPLADSEKLPIQ---KHRNT 824
Query: 138 ENSHDGHNNVEILPPKPDCKLEKKKVELQEKSRWEVLQQEQRLMEEKNKRKKALLAKAIA 197
E S +V ++ K K +KK+ + +EK R +E++ +EK K K K
Sbjct: 825 ETSKSPEKDVPMVEKKSK-KPKKKEKKHKEKER----DKEKKKEKEKKKSPKPKKKKHRK 879
Query: 198 ERSKRTQAETMKLKR 212
E+ +RT+ + K+
Sbjct: 880 EKEERTKGKKKSKKQ 894
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 37.7 bits (86), Expect = 0.009
Identities = 28/97 (28%), Positives = 49/97 (50%), Gaps = 5/97 (5%)
Query: 35 EEELRRLKQTKDPFEPQRRLPAKKSRQQLQREKALVEQSQKLGLQDGSTSLLPEQLLSAP 94
E++L+ K+ ++ L K R Q ++ LV +KL +DG + E LL
Sbjct: 4499 EQKLQGTPSNKEDAAARKPLTPKPKRVQKASDR-LVSSRKKLRKEDGVRA--SEALLKQL 4555
Query: 95 KQRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQ 131
KQ +++ P + P + ++F+L +P G G P +SQ
Sbjct: 4556 KQELSLL--PLTEPAITANFSLFAPFGSGCPVNGQSQ 4590
Score = 28.9 bits (63), Expect = 4.3
Identities = 36/173 (20%), Positives = 71/173 (41%), Gaps = 31/173 (17%)
Query: 35 EEELRRLKQTKDPFEPQRRLPAKKSRQQLQREKALVEQSQKLGLQDGSTSLLPEQLLSAP 94
+++ ++L+Q + Q++ ++ +QQ Q++ +Q Q++GL + S +LL Q
Sbjct: 3934 QQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQ 3993
Query: 95 KQRVNVQKPP-----FSS-------------------PTLPSHFTLTSPVGDGQPQGIES 130
+ + P FSS P + S T G P I +
Sbjct: 3994 QVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGT 4053
Query: 131 QPKELGLE-----NSHDGHNNVEILPPKPDCKLEKKKVELQEKSRWEVLQQEQ 178
P+ + E S G + + ++ P+P + + ++LQ R QQ+Q
Sbjct: 4054 TPESMATEPGEVKPSLSGDSQLLLVQPQP--QPQPSSLQLQPPLRLPGQQQQQ 4104
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 37.0 bits (84), Expect = 0.016
Identities = 39/168 (23%), Positives = 78/168 (46%), Gaps = 20/168 (11%)
Query: 56 AKKSRQQLQREKALVEQSQKLGLQDGSTSLLPEQLLSAPKQRVNVQK--PPFSSPTLPSH 113
A+ +Q L++++A ++Q L Q+ +QLL ++++ Q+ PP P
Sbjct: 260 AQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEE 319
Query: 114 FTLT-SPVGDGQPQGIESQPKELGLENSHDGHNNVEILPPKPDCKLEKKKVELQEKSRWE 172
L PV G Q +E Q +EL + + + ++++ +LQ K + E
Sbjct: 320 VELELMPVDLGSEQELEQQRQELERQQ---------------ELERQQEQRQLQLKLQEE 364
Query: 173 VLQQEQRLMEEKN--KRKKALLAKAIAERSKRTQAETMKLKRIQKELQ 218
+ Q EQ+L +++ ++++ L E + Q ++L +Q ELQ
Sbjct: 365 LQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQPELQ 412
Score = 30.4 bits (67), Expect = 1.5
Identities = 30/149 (20%), Positives = 69/149 (46%), Gaps = 8/149 (5%)
Query: 36 EELRRLKQTKDPFEPQRRLPAKKSRQQLQREKALVEQSQKLGLQDGSTSLLPEQLLSAPK 95
+E +RL+Q ++ + Q+ + +Q LQ+++ L +Q Q+ L L +Q L +
Sbjct: 165 QEQQRLQQQQEQLQTQQA----QEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQ 220
Query: 96 QRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQPKELGLENSHDGHNNVEILPPKPD 155
+++ Q+ L L GQ Q Q ++ L+ ++
Sbjct: 221 EQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQL-- 278
Query: 156 CKLEKKKVELQEKSRWEVLQQEQRLMEEK 184
L +++ +LQ++ + ++LQQ+Q ++++
Sbjct: 279 --LLQQQEQLQQQQQQQLLQQQQEQLQQQ 305
Score = 30.0 bits (66), Expect = 1.9
Identities = 42/207 (20%), Positives = 93/207 (44%), Gaps = 24/207 (11%)
Query: 32 GFSEEELRRLKQTKDPFE---------PQRRLPAKKSRQQ--------LQREKALVEQSQ 74
G E +L++L+Q +P + PQ L ++ QQ LQ+EK Q
Sbjct: 85 GQRELQLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQ 144
Query: 75 KLGLQDGSTSLLPEQLLSAPKQRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQPKE 134
+L + L+ +Q P+Q Q+ L + V Q Q + ++
Sbjct: 145 ELKPE---LQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQ 201
Query: 135 LGLENSHDGHNNVEILPPKPDCK---LEKKKVELQEKSRWEVLQQEQRLMEEKNKRKKAL 191
L+ + ++L + + ++++ +LQ++ + +LQQ+ +L ++ ++++A
Sbjct: 202 QLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQ 261
Query: 192 LAKAIAERSKRTQAETMKLKRIQKELQ 218
L + + E+ ++ Q + L + Q++LQ
Sbjct: 262 LQQQLLEQ-QQAQLQQQLLLQQQEQLQ 287
>gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo
sapiens]
Length = 1185
Score = 36.2 bits (82), Expect = 0.027
Identities = 23/86 (26%), Positives = 44/86 (51%), Gaps = 12/86 (13%)
Query: 137 LENSHDGHNNVEILPPKPDCKLEKKKVELQEKSRWEVLQQEQRLMEEKNKRKKALLAKAI 196
L + + H N+E + + +LE+K ELQ +Q +++ EE NKR + K +
Sbjct: 402 LSKAEERHGNIEERLRQMEAQLEEKNQELQR------ARQREKMNEEHNKRLSDTVDKLL 455
Query: 197 AERSKRTQAETMKLKRIQKELQALDD 222
+E ++R Q +++ + AL+D
Sbjct: 456 SESNERLQL------HLKERMAALED 475
>gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo
sapiens]
Length = 1202
Score = 36.2 bits (82), Expect = 0.027
Identities = 23/86 (26%), Positives = 44/86 (51%), Gaps = 12/86 (13%)
Query: 137 LENSHDGHNNVEILPPKPDCKLEKKKVELQEKSRWEVLQQEQRLMEEKNKRKKALLAKAI 196
L + + H N+E + + +LE+K ELQ +Q +++ EE NKR + K +
Sbjct: 402 LSKAEERHGNIEERLRQMEAQLEEKNQELQR------ARQREKMNEEHNKRLSDTVDKLL 455
Query: 197 AERSKRTQAETMKLKRIQKELQALDD 222
+E ++R Q +++ + AL+D
Sbjct: 456 SESNERLQL------HLKERMAALED 475
>gi|14670392 bromodomain adjacent to zinc finger domain, 1B [Homo
sapiens]
Length = 1483
Score = 35.8 bits (81), Expect = 0.035
Identities = 21/67 (31%), Positives = 40/67 (59%), Gaps = 3/67 (4%)
Query: 150 LPPKPDCKLEKKKVELQEKSRWEVLQQEQRLMEEKNKRKKALLAKAIAERSKRTQAETMK 209
LP + ++K+ L+ K RW + +EQR +E K+K+ L K + E++K + + M
Sbjct: 514 LPEELRSLVQKRYELLEHKKRWASMSEEQR--KEYLKKKREELKKKLKEKAKERREKEM- 570
Query: 210 LKRIQKE 216
L+R++K+
Sbjct: 571 LERLEKQ 577
>gi|20127519 TPX2, microtubule-associated protein homolog [Homo
sapiens]
Length = 747
Score = 35.8 bits (81), Expect = 0.035
Identities = 38/176 (21%), Positives = 73/176 (41%), Gaps = 20/176 (11%)
Query: 34 SEEELRRLKQTKDPFEPQRRLPAKKSRQQLQREKALVEQSQKLGLQDGSTSLLPEQLLSA 93
S E+ K P +PQRR +++ L++++ + K+ + +T ++ +++L +
Sbjct: 101 SSLEVEAAISRKTPAQPQRRSLRLSAQKDLEQKE---KHHVKMKAKRCATPVIIDEILPS 157
Query: 94 PKQRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQPKELGLENSHDGHNNVEILPPK 153
K +V+ K P +G ++ K G + V +PP
Sbjct: 158 KKMKVSNNKK--------------KPEEEGSAHQ-DTAEKNASSPEKAKGRHTVPCMPPA 202
Query: 154 PDCKLEKKKVELQEKSRWEVLQQEQRLMEEKNKRKKALLAKAIAERSKRTQAETMK 209
L K E QE + +QQE M +KN+ K L I + K++ ++ K
Sbjct: 203 KQKFL--KSTEEQELEKSMKMQQEVVEMRKKNEEFKKLALAGIGQPVKKSVSQVTK 256
>gi|70166430 GRINL1A combined protein isoform 2 [Homo sapiens]
Length = 445
Score = 35.8 bits (81), Expect = 0.035
Identities = 50/222 (22%), Positives = 94/222 (42%), Gaps = 32/222 (14%)
Query: 29 GWAGFS-EEELRRLKQTKDPFEPQRRLPAKKSRQQLQREKALVEQSQKLGLQDGSTSLLP 87
GW+ +EE+ +K + E R+ + Q+ + L +Q+L + L
Sbjct: 91 GWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQL---TQELSVSHAQQEYLE 147
Query: 88 E--QLLSAPKQRVNVQKPPFSSPTLPSHFTLTSPVGDG-----QPQGIESQPKELGLENS 140
Q S+ R N +S ++ TL + Q + ++ Q E ++
Sbjct: 148 NHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQ-QTYEASMDKL 206
Query: 141 HDGHNNVEILPPKPDCKLEKKKVELQEKSRWEVL---------QQEQRLMEEKNKR---K 188
+ +E+ + + +L K KVE +++ EV+ Q E++L EE+ K K
Sbjct: 207 REKQRQLEVA--QVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEK 264
Query: 189 KALLA------KAIAERSKRTQAETMKLKRIQKELQALDDMV 224
+ALL KAI E +K+ QA + L+ + + LD ++
Sbjct: 265 EALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLI 306
>gi|70166414 GRINL1A combined protein isoform 1 [Homo sapiens]
Length = 550
Score = 35.8 bits (81), Expect = 0.035
Identities = 50/222 (22%), Positives = 94/222 (42%), Gaps = 32/222 (14%)
Query: 29 GWAGFS-EEELRRLKQTKDPFEPQRRLPAKKSRQQLQREKALVEQSQKLGLQDGSTSLLP 87
GW+ +EE+ +K + E R+ + Q+ + L +Q+L + L
Sbjct: 91 GWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQL---TQELSVSHAQQEYLE 147
Query: 88 E--QLLSAPKQRVNVQKPPFSSPTLPSHFTLTSPVGDG-----QPQGIESQPKELGLENS 140
Q S+ R N +S ++ TL + Q + ++ Q E ++
Sbjct: 148 NHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQ-QTYEASMDKL 206
Query: 141 HDGHNNVEILPPKPDCKLEKKKVELQEKSRWEVL---------QQEQRLMEEKNKR---K 188
+ +E+ + + +L K KVE +++ EV+ Q E++L EE+ K K
Sbjct: 207 REKQRQLEVA--QVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEK 264
Query: 189 KALLA------KAIAERSKRTQAETMKLKRIQKELQALDDMV 224
+ALL KAI E +K+ QA + L+ + + LD ++
Sbjct: 265 EALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLI 306
>gi|111494235 GRINL1A combined protein isoform 8 [Homo sapiens]
Length = 438
Score = 35.8 bits (81), Expect = 0.035
Identities = 50/222 (22%), Positives = 94/222 (42%), Gaps = 32/222 (14%)
Query: 29 GWAGFS-EEELRRLKQTKDPFEPQRRLPAKKSRQQLQREKALVEQSQKLGLQDGSTSLLP 87
GW+ +EE+ +K + E R+ + Q+ + L +Q+L + L
Sbjct: 91 GWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQL---TQELSVSHAQQEYLE 147
Query: 88 E--QLLSAPKQRVNVQKPPFSSPTLPSHFTLTSPVGDG-----QPQGIESQPKELGLENS 140
Q S+ R N +S ++ TL + Q + ++ Q E ++
Sbjct: 148 NHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQ-QTYEASMDKL 206
Query: 141 HDGHNNVEILPPKPDCKLEKKKVELQEKSRWEVL---------QQEQRLMEEKNKR---K 188
+ +E+ + + +L K KVE +++ EV+ Q E++L EE+ K K
Sbjct: 207 REKQRQLEVA--QVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEK 264
Query: 189 KALLA------KAIAERSKRTQAETMKLKRIQKELQALDDMV 224
+ALL KAI E +K+ QA + L+ + + LD ++
Sbjct: 265 EALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLI 306
>gi|70166580 GRINL1A upstream protein isoform 7 [Homo sapiens]
Length = 466
Score = 35.8 bits (81), Expect = 0.035
Identities = 50/222 (22%), Positives = 94/222 (42%), Gaps = 32/222 (14%)
Query: 29 GWAGFS-EEELRRLKQTKDPFEPQRRLPAKKSRQQLQREKALVEQSQKLGLQDGSTSLLP 87
GW+ +EE+ +K + E R+ + Q+ + L +Q+L + L
Sbjct: 91 GWSTSQLKEEMNYIKDVRATLEKVRKRMYGDYDEMRQKIRQL---TQELSVSHAQQEYLE 147
Query: 88 E--QLLSAPKQRVNVQKPPFSSPTLPSHFTLTSPVGDG-----QPQGIESQPKELGLENS 140
Q S+ R N +S ++ TL + Q + ++ Q E ++
Sbjct: 148 NHIQTQSSALDRFNAMNSALASDSIGLQKTLVDVTLENSNIKDQIRNLQ-QTYEASMDKL 206
Query: 141 HDGHNNVEILPPKPDCKLEKKKVELQEKSRWEVL---------QQEQRLMEEKNKR---K 188
+ +E+ + + +L K KVE +++ EV+ Q E++L EE+ K K
Sbjct: 207 REKQRQLEVA--QVENQLLKMKVESSQEANAEVMREMTKKLYSQYEEKLQEEQRKHSAEK 264
Query: 189 KALLA------KAIAERSKRTQAETMKLKRIQKELQALDDMV 224
+ALL KAI E +K+ QA + L+ + + LD ++
Sbjct: 265 EALLEETNSFLKAIEEANKKMQAAEISLEEKDQRIGELDRLI 306
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 35.4 bits (80), Expect = 0.046
Identities = 39/190 (20%), Positives = 82/190 (43%), Gaps = 29/190 (15%)
Query: 29 GWAGFSEEELRRLKQTKDPFEPQRRLPAKKSRQQLQREKALVEQSQKL--GLQDGSTSLL 86
GW E R ++ K+ + +R KK R++ ++ K E+ +K G ++
Sbjct: 33 GWQSEIREREREIETRKEG-KKERESERKKERREREKRKREREKERKRERGKKEKKGERK 91
Query: 87 PEQLLSAPKQRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQPKELGLENSHDGHNN 146
E+ ++R K G+ + + + + KE G S +G
Sbjct: 92 KEERERKKRRREKENKE-----------------GEEKEKRKKKEKKERG-RTSKEGKER 133
Query: 147 VEILPPKPDCKLEKKKVELQEKSRWEVLQQEQRLMEEKNKRKKALLAKAIAERSKRTQAE 206
+ K E+K+ E +E+ R + ++++R +E+ KR++ + + ER ++ + E
Sbjct: 134 --------ERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKE 185
Query: 207 TMKLKRIQKE 216
K +R +KE
Sbjct: 186 RKKRERNRKE 195
Score = 29.3 bits (64), Expect = 3.3
Identities = 20/63 (31%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
Query: 157 KLEKKKVELQEKSRWEVLQQEQRLMEE-KNKRKKALLAKAIAERSKRTQAETMKLKRIQK 215
K E+K+V +E+ R E ++E++ E + +RKK K ER K + + + K QK
Sbjct: 165 KRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQK 224
Query: 216 ELQ 218
+ Q
Sbjct: 225 DRQ 227
>gi|55749678 ninein-like [Homo sapiens]
Length = 1382
Score = 35.4 bits (80), Expect = 0.046
Identities = 52/209 (24%), Positives = 84/209 (40%), Gaps = 28/209 (13%)
Query: 23 PGPMAQGWAGFSE---EELRRLKQTKDPFEPQRRL------PAKKSRQQLQREKALVEQS 73
P P AG + EL L +D + Q R+ PA R Q +R +A+ E+
Sbjct: 923 PEPFGASAAGLEQPGARELPLLGTERDASQTQPRMWEPPLRPAASCRGQAERLQAIQEER 982
Query: 74 QKLGLQDGSTSLLPEQLLSAP--------KQRVNVQKPPFSSPTLPSHFTLTSPVGDGQP 125
+ G+ EQ A K V V + +LPSH L P G Q
Sbjct: 983 AR-SWSRGTQEQASEQQARAEGALEPGCHKHSVEVAR----RGSLPSHLQLADPQGSWQE 1037
Query: 126 Q--GIESQPKELGLENSHDGHNNVEILPPKPDCKLEKKKVELQEKSRWEV--LQQEQRLM 181
Q E ++ LE D ++L + + +K V+L+E R E L +E L+
Sbjct: 1038 QLAAPEEGETKIALEREKD-DMETKLLHLEDVVRALEKHVDLRENDRLEFHRLSEENTLL 1096
Query: 182 E-EKNKRKKALLAKAIAERSKRTQAETMK 209
+ + + ++ L A ++R + E +K
Sbjct: 1097 KNDLGRVRQELEAAESTHDAQRKEIEVLK 1125
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 35.4 bits (80), Expect = 0.046
Identities = 53/208 (25%), Positives = 84/208 (40%), Gaps = 45/208 (21%)
Query: 34 SEEELRRLKQTKDP-FEPQRRLPAKKSRQQLQREKALVEQSQKLGLQDGSTSLLPEQL-- 90
+E+ R KQ D E ++ + RQ+ Q E+ L +L D +LL E+L
Sbjct: 2152 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2211
Query: 91 -----LSAPKQRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQPKELG-LENSHDGH 144
A +QR V++ FS + Q +EL L+ +
Sbjct: 2212 LKAEATEAARQRSQVEEELFS---------------------VRVQMEELSKLKARIEAE 2250
Query: 145 NNVEILPPKPDC------KLEKKKVELQEKSRWEVLQQE----QRLMEEKNKRKKALLAK 194
N IL K + + EK K +E +R V QE ++L EE +++AL K
Sbjct: 2251 NRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2310
Query: 195 AIAERSKRTQAET-----MKLKRIQKEL 217
+ E+ + Q T +L + QKEL
Sbjct: 2311 MLKEKMQAVQEATRLKAEAELLQQQKEL 2338
Score = 30.0 bits (66), Expect = 1.9
Identities = 17/69 (24%), Positives = 41/69 (59%), Gaps = 5/69 (7%)
Query: 158 LEKKKVELQEKSRWEV-----LQQEQRLMEEKNKRKKALLAKAIAERSKRTQAETMKLKR 212
+E++K +L++ + EV L++EQ+ +++ ++++ L ++ E +R ++R
Sbjct: 2509 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2568
Query: 213 IQKELQALD 221
Q+ELQ L+
Sbjct: 2569 KQEELQQLE 2577
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 35.4 bits (80), Expect = 0.046
Identities = 53/208 (25%), Positives = 84/208 (40%), Gaps = 45/208 (21%)
Query: 34 SEEELRRLKQTKDP-FEPQRRLPAKKSRQQLQREKALVEQSQKLGLQDGSTSLLPEQL-- 90
+E+ R KQ D E ++ + RQ+ Q E+ L +L D +LL E+L
Sbjct: 2156 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2215
Query: 91 -----LSAPKQRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQPKELG-LENSHDGH 144
A +QR V++ FS + Q +EL L+ +
Sbjct: 2216 LKAEATEAARQRSQVEEELFS---------------------VRVQMEELSKLKARIEAE 2254
Query: 145 NNVEILPPKPDC------KLEKKKVELQEKSRWEVLQQE----QRLMEEKNKRKKALLAK 194
N IL K + + EK K +E +R V QE ++L EE +++AL K
Sbjct: 2255 NRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2314
Query: 195 AIAERSKRTQAET-----MKLKRIQKEL 217
+ E+ + Q T +L + QKEL
Sbjct: 2315 MLKEKMQAVQEATRLKAEAELLQQQKEL 2342
Score = 30.0 bits (66), Expect = 1.9
Identities = 17/69 (24%), Positives = 41/69 (59%), Gaps = 5/69 (7%)
Query: 158 LEKKKVELQEKSRWEV-----LQQEQRLMEEKNKRKKALLAKAIAERSKRTQAETMKLKR 212
+E++K +L++ + EV L++EQ+ +++ ++++ L ++ E +R ++R
Sbjct: 2513 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2572
Query: 213 IQKELQALD 221
Q+ELQ L+
Sbjct: 2573 KQEELQQLE 2581
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 35.4 bits (80), Expect = 0.046
Identities = 53/208 (25%), Positives = 84/208 (40%), Gaps = 45/208 (21%)
Query: 34 SEEELRRLKQTKDP-FEPQRRLPAKKSRQQLQREKALVEQSQKLGLQDGSTSLLPEQL-- 90
+E+ R KQ D E ++ + RQ+ Q E+ L +L D +LL E+L
Sbjct: 2152 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2211
Query: 91 -----LSAPKQRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQPKELG-LENSHDGH 144
A +QR V++ FS + Q +EL L+ +
Sbjct: 2212 LKAEATEAARQRSQVEEELFS---------------------VRVQMEELSKLKARIEAE 2250
Query: 145 NNVEILPPKPDC------KLEKKKVELQEKSRWEVLQQE----QRLMEEKNKRKKALLAK 194
N IL K + + EK K +E +R V QE ++L EE +++AL K
Sbjct: 2251 NRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2310
Query: 195 AIAERSKRTQAET-----MKLKRIQKEL 217
+ E+ + Q T +L + QKEL
Sbjct: 2311 MLKEKMQAVQEATRLKAEAELLQQQKEL 2338
Score = 30.0 bits (66), Expect = 1.9
Identities = 17/69 (24%), Positives = 41/69 (59%), Gaps = 5/69 (7%)
Query: 158 LEKKKVELQEKSRWEV-----LQQEQRLMEEKNKRKKALLAKAIAERSKRTQAETMKLKR 212
+E++K +L++ + EV L++EQ+ +++ ++++ L ++ E +R ++R
Sbjct: 2509 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2568
Query: 213 IQKELQALD 221
Q+ELQ L+
Sbjct: 2569 KQEELQQLE 2577
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 35.4 bits (80), Expect = 0.046
Identities = 53/208 (25%), Positives = 84/208 (40%), Gaps = 45/208 (21%)
Query: 34 SEEELRRLKQTKDP-FEPQRRLPAKKSRQQLQREKALVEQSQKLGLQDGSTSLLPEQL-- 90
+E+ R KQ D E ++ + RQ+ Q E+ L +L D +LL E+L
Sbjct: 2120 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2179
Query: 91 -----LSAPKQRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQPKELG-LENSHDGH 144
A +QR V++ FS + Q +EL L+ +
Sbjct: 2180 LKAEATEAARQRSQVEEELFS---------------------VRVQMEELSKLKARIEAE 2218
Query: 145 NNVEILPPKPDC------KLEKKKVELQEKSRWEVLQQE----QRLMEEKNKRKKALLAK 194
N IL K + + EK K +E +R V QE ++L EE +++AL K
Sbjct: 2219 NRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2278
Query: 195 AIAERSKRTQAET-----MKLKRIQKEL 217
+ E+ + Q T +L + QKEL
Sbjct: 2279 MLKEKMQAVQEATRLKAEAELLQQQKEL 2306
Score = 30.0 bits (66), Expect = 1.9
Identities = 17/69 (24%), Positives = 41/69 (59%), Gaps = 5/69 (7%)
Query: 158 LEKKKVELQEKSRWEV-----LQQEQRLMEEKNKRKKALLAKAIAERSKRTQAETMKLKR 212
+E++K +L++ + EV L++EQ+ +++ ++++ L ++ E +R ++R
Sbjct: 2477 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2536
Query: 213 IQKELQALD 221
Q+ELQ L+
Sbjct: 2537 KQEELQQLE 2545
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 35.4 bits (80), Expect = 0.046
Identities = 53/208 (25%), Positives = 84/208 (40%), Gaps = 45/208 (21%)
Query: 34 SEEELRRLKQTKDP-FEPQRRLPAKKSRQQLQREKALVEQSQKLGLQDGSTSLLPEQL-- 90
+E+ R KQ D E ++ + RQ+ Q E+ L +L D +LL E+L
Sbjct: 2289 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2348
Query: 91 -----LSAPKQRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQPKELG-LENSHDGH 144
A +QR V++ FS + Q +EL L+ +
Sbjct: 2349 LKAEATEAARQRSQVEEELFS---------------------VRVQMEELSKLKARIEAE 2387
Query: 145 NNVEILPPKPDC------KLEKKKVELQEKSRWEVLQQE----QRLMEEKNKRKKALLAK 194
N IL K + + EK K +E +R V QE ++L EE +++AL K
Sbjct: 2388 NRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2447
Query: 195 AIAERSKRTQAET-----MKLKRIQKEL 217
+ E+ + Q T +L + QKEL
Sbjct: 2448 MLKEKMQAVQEATRLKAEAELLQQQKEL 2475
Score = 30.0 bits (66), Expect = 1.9
Identities = 17/69 (24%), Positives = 41/69 (59%), Gaps = 5/69 (7%)
Query: 158 LEKKKVELQEKSRWEV-----LQQEQRLMEEKNKRKKALLAKAIAERSKRTQAETMKLKR 212
+E++K +L++ + EV L++EQ+ +++ ++++ L ++ E +R ++R
Sbjct: 2646 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2705
Query: 213 IQKELQALD 221
Q+ELQ L+
Sbjct: 2706 KQEELQQLE 2714
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 35.4 bits (80), Expect = 0.046
Identities = 53/208 (25%), Positives = 84/208 (40%), Gaps = 45/208 (21%)
Query: 34 SEEELRRLKQTKDP-FEPQRRLPAKKSRQQLQREKALVEQSQKLGLQDGSTSLLPEQL-- 90
+E+ R KQ D E ++ + RQ+ Q E+ L +L D +LL E+L
Sbjct: 2130 AEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQR 2189
Query: 91 -----LSAPKQRVNVQKPPFSSPTLPSHFTLTSPVGDGQPQGIESQPKELG-LENSHDGH 144
A +QR V++ FS + Q +EL L+ +
Sbjct: 2190 LKAEATEAARQRSQVEEELFS---------------------VRVQMEELSKLKARIEAE 2228
Query: 145 NNVEILPPKPDC------KLEKKKVELQEKSRWEVLQQE----QRLMEEKNKRKKALLAK 194
N IL K + + EK K +E +R V QE ++L EE +++AL K
Sbjct: 2229 NRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEK 2288
Query: 195 AIAERSKRTQAET-----MKLKRIQKEL 217
+ E+ + Q T +L + QKEL
Sbjct: 2289 MLKEKMQAVQEATRLKAEAELLQQQKEL 2316
Score = 30.0 bits (66), Expect = 1.9
Identities = 17/69 (24%), Positives = 41/69 (59%), Gaps = 5/69 (7%)
Query: 158 LEKKKVELQEKSRWEV-----LQQEQRLMEEKNKRKKALLAKAIAERSKRTQAETMKLKR 212
+E++K +L++ + EV L++EQ+ +++ ++++ L ++ E +R ++R
Sbjct: 2487 IEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRR 2546
Query: 213 IQKELQALD 221
Q+ELQ L+
Sbjct: 2547 KQEELQQLE 2555
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.129 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,040,818
Number of Sequences: 37866
Number of extensions: 518474
Number of successful extensions: 3985
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 92
Number of HSP's successfully gapped in prelim test: 333
Number of HSP's that attempted gapping in prelim test: 3064
Number of HSP's gapped (non-prelim): 1204
length of query: 246
length of database: 18,247,518
effective HSP length: 100
effective length of query: 146
effective length of database: 14,460,918
effective search space: 2111294028
effective search space used: 2111294028
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.