Search of human proteins with 225637524

Search of human proteins with 225637524

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|225637524 semaphorin 7A isoform 3 [Homo sapiens]
         (501 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens]      1053   0.0  
gi|225637524 semaphorin 7A isoform 3 [Homo sapiens]                  1053   0.0  
gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens]    1053   0.0  
gi|39777610 semaphorin 4B precursor [Homo sapiens]                    210   2e-54
gi|39777608 semaphorin 4B precursor [Homo sapiens]                    210   2e-54
gi|5454048 semaphorin 3C [Homo sapiens]                               207   1e-53
gi|5174673 semaphorin 3A precursor [Homo sapiens]                     207   2e-53
gi|54607089 semaphorin 3B isoform 2 precursor [Homo sapiens]          203   3e-52
gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens]           203   3e-52
gi|188497703 semaphorin 3F [Homo sapiens]                             194   1e-49
gi|41406086 semaphorin 3D [Homo sapiens]                              180   2e-45
gi|6912650 semaphorin 3E [Homo sapiens]                               178   1e-44
gi|214010218 semaphorin 4D isoform 1 [Homo sapiens]                   170   3e-42
gi|9910362 semaphorin sem2 [Homo sapiens]                             169   7e-42
gi|214010220 semaphorin 4D isoform 2 [Homo sapiens]                   166   6e-41
gi|19923279 semaphorin W [Homo sapiens]                               157   2e-38
gi|157388902 semaphorin 4C [Homo sapiens]                             153   3e-37
gi|21361914 semaphorin B [Homo sapiens]                               152   5e-37
gi|28872814 semaphorin 4G [Homo sapiens]                              148   1e-35
gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens]          116   4e-26
gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens]          116   4e-26
gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]          116   4e-26
gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]          116   4e-26
gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens]          116   4e-26
gi|11991660 sema domain, transmembrane domain (TM), and cytoplas...   115   1e-25
gi|16306552 semaphorin Y [Homo sapiens]                               113   5e-25
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]                    112   6e-25
gi|147904700 semaphorin 5A [Homo sapiens]                             110   2e-24
gi|19718780 semaphorin 6B precursor [Homo sapiens]                     99   1e-20
gi|24234732 semaphorin 6D isoform 6 precursor [Homo sapiens]           78   2e-14

>gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens]
          Length = 666

 Score = 1053 bits (2724), Expect = 0.0
 Identities = 501/501 (100%), Positives = 501/501 (100%)

Query: 1   MRGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFI 60
           MRGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFI
Sbjct: 166 MRGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFI 225

Query: 61  KATIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFL 120
           KATIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFL
Sbjct: 226 KATIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFL 285

Query: 121 KAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDKV 180
           KAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDKV
Sbjct: 286 KAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDKV 345

Query: 181 FRTSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSK 240
           FRTSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSK
Sbjct: 346 FRTSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSK 405

Query: 241 YHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAI 300
           YHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAI
Sbjct: 406 YHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAI 465

Query: 301 QTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQGRCISIYSSE 360
           QTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQGRCISIYSSE
Sbjct: 466 QTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQGRCISIYSSE 525

Query: 361 RSVLQSINPAEPHKECPNPKPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQ 420
           RSVLQSINPAEPHKECPNPKPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQ
Sbjct: 526 RSVLQSINPAEPHKECPNPKPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQ 585

Query: 421 SCEPGHQSPNCILFIENLTAQQYGHYFCEAQEGSYFREAQHWQLLPEDGIMAEHLLGHAC 480
           SCEPGHQSPNCILFIENLTAQQYGHYFCEAQEGSYFREAQHWQLLPEDGIMAEHLLGHAC
Sbjct: 586 SCEPGHQSPNCILFIENLTAQQYGHYFCEAQEGSYFREAQHWQLLPEDGIMAEHLLGHAC 645

Query: 481 ALAASLWLGVLPTLTLGLLVH 501
           ALAASLWLGVLPTLTLGLLVH
Sbjct: 646 ALAASLWLGVLPTLTLGLLVH 666


>gi|225637524 semaphorin 7A isoform 3 [Homo sapiens]
          Length = 501

 Score = 1053 bits (2724), Expect = 0.0
 Identities = 501/501 (100%), Positives = 501/501 (100%)

Query: 1   MRGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFI 60
           MRGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFI
Sbjct: 1   MRGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFI 60

Query: 61  KATIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFL 120
           KATIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFL
Sbjct: 61  KATIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFL 120

Query: 121 KAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDKV 180
           KAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDKV
Sbjct: 121 KAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDKV 180

Query: 181 FRTSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSK 240
           FRTSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSK
Sbjct: 181 FRTSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSK 240

Query: 241 YHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAI 300
           YHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAI
Sbjct: 241 YHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAI 300

Query: 301 QTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQGRCISIYSSE 360
           QTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQGRCISIYSSE
Sbjct: 301 QTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQGRCISIYSSE 360

Query: 361 RSVLQSINPAEPHKECPNPKPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQ 420
           RSVLQSINPAEPHKECPNPKPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQ
Sbjct: 361 RSVLQSINPAEPHKECPNPKPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQ 420

Query: 421 SCEPGHQSPNCILFIENLTAQQYGHYFCEAQEGSYFREAQHWQLLPEDGIMAEHLLGHAC 480
           SCEPGHQSPNCILFIENLTAQQYGHYFCEAQEGSYFREAQHWQLLPEDGIMAEHLLGHAC
Sbjct: 421 SCEPGHQSPNCILFIENLTAQQYGHYFCEAQEGSYFREAQHWQLLPEDGIMAEHLLGHAC 480

Query: 481 ALAASLWLGVLPTLTLGLLVH 501
           ALAASLWLGVLPTLTLGLLVH
Sbjct: 481 ALAASLWLGVLPTLTLGLLVH 501


>gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens]
          Length = 652

 Score = 1053 bits (2724), Expect = 0.0
 Identities = 501/501 (100%), Positives = 501/501 (100%)

Query: 1   MRGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFI 60
           MRGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFI
Sbjct: 152 MRGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFI 211

Query: 61  KATIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFL 120
           KATIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFL
Sbjct: 212 KATIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFL 271

Query: 121 KAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDKV 180
           KAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDKV
Sbjct: 272 KAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDKV 331

Query: 181 FRTSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSK 240
           FRTSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSK
Sbjct: 332 FRTSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSK 391

Query: 241 YHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAI 300
           YHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAI
Sbjct: 392 YHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAI 451

Query: 301 QTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQGRCISIYSSE 360
           QTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQGRCISIYSSE
Sbjct: 452 QTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQGRCISIYSSE 511

Query: 361 RSVLQSINPAEPHKECPNPKPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQ 420
           RSVLQSINPAEPHKECPNPKPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQ
Sbjct: 512 RSVLQSINPAEPHKECPNPKPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQ 571

Query: 421 SCEPGHQSPNCILFIENLTAQQYGHYFCEAQEGSYFREAQHWQLLPEDGIMAEHLLGHAC 480
           SCEPGHQSPNCILFIENLTAQQYGHYFCEAQEGSYFREAQHWQLLPEDGIMAEHLLGHAC
Sbjct: 572 SCEPGHQSPNCILFIENLTAQQYGHYFCEAQEGSYFREAQHWQLLPEDGIMAEHLLGHAC 631

Query: 481 ALAASLWLGVLPTLTLGLLVH 501
           ALAASLWLGVLPTLTLGLLVH
Sbjct: 632 ALAASLWLGVLPTLTLGLLVH 652


>gi|39777610 semaphorin 4B precursor [Homo sapiens]
          Length = 837

 Score =  210 bits (535), Expect = 2e-54
 Identities = 162/511 (31%), Positives = 237/511 (46%), Gaps = 55/511 (10%)

Query: 2   RGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTV--MQNPQF 59
           +G  PF P+  S  L    E+Y T     + G  P   R +      T  ++  +Q+P F
Sbjct: 182 KGRCPFDPNFKSTALVVDGELY-TGTVSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAF 240

Query: 60  IKATIVHQD----QAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSK 115
           + +  + +     Q  DDKIY+FF E   +        VSR+A++C+GD+GGE  L   +
Sbjct: 241 VASAYIPESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQ-QR 299

Query: 116 WNTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY-----SAVC 170
           W +FLKA L+CS       FN LQDVF L      WRDT  YGVF++ W+      SAVC
Sbjct: 300 WTSFLKAQLLCSRPDDGFPFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVC 359

Query: 171 VYSLGDIDKVF---------RTSSLKGYHSSLPNPRPGKCLPD--QQPIPTETFQVADRH 219
           V+++ D+ +VF          T         +P PRPG C+ +  ++     + Q+ DR 
Sbjct: 360 VFTMKDVQRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRV 419

Query: 220 PEVAQ---RVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVE 276
               +    ++     +  L   +  YQ+VAVHR+   H  T+ VL+L T  G +HK V 
Sbjct: 420 LNFLKDHFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLH-HTYDVLFLGTGDGRLHKAVS 478

Query: 277 PGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCH 336
            G + H     I E+Q F     +Q + LD  R  LY +S   V QVP+  C +Y   C 
Sbjct: 479 VGPRVHI----IEELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLY-RSCG 533

Query: 337 GCLMSRDPYCGWDQGRC--ISIYSSE---RSVLQSINPAEPHKEC-------PNPKP-DK 383
            CL++RDPYC W    C  +S+Y  +   R  +Q I  A     C       P+  P  +
Sbjct: 534 DCLLARDPYCAWSGSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSASSVVSPSFVPTGE 593

Query: 384 APLQKVSLAPNSRYYLSCPMESRHATYSWRHK---ENVEQSCEPGHQSPNCILFIENLTA 440
            P ++V   PN+   L+CP+ S  AT  W       N   SC   H  P   L +  +  
Sbjct: 594 KPCEQVQFQPNTVNTLACPLLSNLATRLWLRNGAPVNASASC---HVLPTGDLLL--VGT 648

Query: 441 QQYGHYFC-EAQEGSYFREAQHWQLLPEDGI 470
           QQ G + C   +EG     A +   + EDG+
Sbjct: 649 QQLGEFQCWSLEEGFQQLVASYCPEVVEDGV 679


>gi|39777608 semaphorin 4B precursor [Homo sapiens]
          Length = 837

 Score =  210 bits (535), Expect = 2e-54
 Identities = 162/511 (31%), Positives = 237/511 (46%), Gaps = 55/511 (10%)

Query: 2   RGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTV--MQNPQF 59
           +G  PF P+  S  L    E+Y T     + G  P   R +      T  ++  +Q+P F
Sbjct: 182 KGRCPFDPNFKSTALVVDGELY-TGTVSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAF 240

Query: 60  IKATIVHQD----QAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSK 115
           + +  + +     Q  DDKIY+FF E   +        VSR+A++C+GD+GGE  L   +
Sbjct: 241 VASAYIPESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQ-QR 299

Query: 116 WNTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY-----SAVC 170
           W +FLKA L+CS       FN LQDVF L      WRDT  YGVF++ W+      SAVC
Sbjct: 300 WTSFLKAQLLCSRPDDGFPFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVC 359

Query: 171 VYSLGDIDKVF---------RTSSLKGYHSSLPNPRPGKCLPD--QQPIPTETFQVADRH 219
           V+++ D+ +VF          T         +P PRPG C+ +  ++     + Q+ DR 
Sbjct: 360 VFTMKDVQRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRV 419

Query: 220 PEVAQ---RVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVE 276
               +    ++     +  L   +  YQ+VAVHR+   H  T+ VL+L T  G +HK V 
Sbjct: 420 LNFLKDHFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLH-HTYDVLFLGTGDGRLHKAVS 478

Query: 277 PGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCH 336
            G + H     I E+Q F     +Q + LD  R  LY +S   V QVP+  C +Y   C 
Sbjct: 479 VGPRVHI----IEELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLY-RSCG 533

Query: 337 GCLMSRDPYCGWDQGRC--ISIYSSE---RSVLQSINPAEPHKEC-------PNPKP-DK 383
            CL++RDPYC W    C  +S+Y  +   R  +Q I  A     C       P+  P  +
Sbjct: 534 DCLLARDPYCAWSGSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSASSVVSPSFVPTGE 593

Query: 384 APLQKVSLAPNSRYYLSCPMESRHATYSWRHK---ENVEQSCEPGHQSPNCILFIENLTA 440
            P ++V   PN+   L+CP+ S  AT  W       N   SC   H  P   L +  +  
Sbjct: 594 KPCEQVQFQPNTVNTLACPLLSNLATRLWLRNGAPVNASASC---HVLPTGDLLL--VGT 648

Query: 441 QQYGHYFC-EAQEGSYFREAQHWQLLPEDGI 470
           QQ G + C   +EG     A +   + EDG+
Sbjct: 649 QQLGEFQCWSLEEGFQQLVASYCPEVVEDGV 679


>gi|5454048 semaphorin 3C [Homo sapiens]
          Length = 751

 Score =  207 bits (528), Expect = 1e-53
 Identities = 155/494 (31%), Positives = 234/494 (47%), Gaps = 46/494 (9%)

Query: 2   RGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYT---SDTVMQNPQ 58
           +G   F+P+ N++ +   +E++S +           FR +   + + T   +   +  P 
Sbjct: 163 KGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPM 222

Query: 59  FIKATIVHQDQAYDD-KIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWN 117
           F+ A ++      +D K+Y+FF+E   D N       S +A++C  D GG  SL V+KW 
Sbjct: 223 FVDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSL-VNKWT 281

Query: 118 TFLKAMLVCS---DAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVF---SNPWNYSAVCV 171
           TFLKA LVCS   +     +F+ L+DVFLL   +   R T VYG+F   S+ +  SAVCV
Sbjct: 282 TFLKARLVCSVTDEDGPETHFDELEDVFLLETDNP--RTTLVYGIFTTSSSVFKGSAVCV 339

Query: 172 YSLGDIDKVFR---------TSSLKGYHSSLPNPRPGKC--------LPDQQPIPTETFQ 214
           Y L DI  VF             L  Y   +P PRPG C        +   +  P +   
Sbjct: 340 YHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVT 399

Query: 215 VADRHPEVAQRVEPMGPLKTPLF---HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTI 271
               HP +   + P+   K PL     + Y Y K+AV R+ A+ G  +HVL+L TDRGT+
Sbjct: 400 FIRNHPLMYNSIYPIH--KRPLIVRIGTDYKYTKIAVDRVNAADGR-YHVLFLGTDRGTV 456

Query: 272 HKVVE-PGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEV 330
            KVV  P     S    + E++ F+  A I TM + +++++LYVSS   VSQV L  C +
Sbjct: 457 QKVVVLPTNNSVSGELILEELEVFKNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHI 516

Query: 331 YGGGCHGCLMSRDPYCGWDQGRCISIY--SSERSVLQSINPAEPHKECP--NPKPDKAPL 386
           YG  C  C ++RDPYC WD   C   Y     RS  Q +    P  +C   N K  +   
Sbjct: 517 YGTACADCCLARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAA 576

Query: 387 QKVSL-APNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQ----SPNCILFIENLTAQ 441
           + V     N+  +L C  +S  A+  W  +++ ++  E        + +  L I ++   
Sbjct: 577 EIVQYGVKNNTTFLECAPKSPQASIKWLLQKDKDRRKEVKLNERIIATSQGLLIRSVQGS 636

Query: 442 QYGHYFCEAQEGSY 455
             G Y C A E S+
Sbjct: 637 DQGLYHCIATENSF 650


>gi|5174673 semaphorin 3A precursor [Homo sapiens]
          Length = 771

 Score =  207 bits (527), Expect = 2e-53
 Identities = 152/502 (30%), Positives = 237/502 (47%), Gaps = 55/502 (10%)

Query: 2   RGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSD---TVMQNPQ 58
           RG +P+ P   +  L    E+YS             FR +     + T       + +P+
Sbjct: 166 RGKSPYDPKLLTASLLIDGELYSGTAADFMGRDFAIFRTLGHHHPIRTEQHDSRWLNDPK 225

Query: 59  FIKATIVHQ-DQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWN 117
           FI A ++ + D   DDK+Y+FFRE+  D         +R+ Q+C+ D GG  SL V+KW 
Sbjct: 226 FISAHLISESDNPEDDKVYFFFRENAIDGEHSGKATHARIGQICKNDFGGHRSL-VNKWT 284

Query: 118 TFLKAMLVCSDAATN---KNFNRLQDVFLL--PDPSGQWRDTRVYGVF---SNPWNYSAV 169
           TFLKA L+CS    N    +F+ LQDVFL+   DP    ++  VYGVF   SN +  SAV
Sbjct: 285 TFLKARLICSVPGPNGIDTHFDELQDVFLMNFKDP----KNPVVYGVFTTSSNIFKGSAV 340

Query: 170 CVYSLGDIDKVFR---------TSSLKGYHSSLPNPRPGKC-------LPDQQPIPTETF 213
           C+YS+ D+ +VF                Y   +P PRPG C           + +P +  
Sbjct: 341 CMYSMSDVRRVFLGPYAHRDGPNYQWVPYQGRVPYPRPGTCPSKTFGGFDSTKDLPDDVI 400

Query: 214 QVADRHPEVAQRVEPMGP----LKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRG 269
             A  HP +   V PM      +KT +    Y + ++ V R+ A  G+ + V+++ TD G
Sbjct: 401 TFARSHPAMYNPVFPMNNRPIVIKTDV---NYQFTQIVVDRVDAEDGQ-YDVMFIGTDVG 456

Query: 270 TIHKVVE-PGEQEHSFAFNIME-IQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDL 327
           T+ KVV  P E  +     ++E +  FR   AI  M L  ++++LY+ S   V+Q+PL  
Sbjct: 457 TVLKVVSIPKETWYDLEEVLLEEMTVFREPTAISAMELSTKQQQLYIGSTAGVAQLPLHR 516

Query: 328 CEVYGGGCHGCLMSRDPYCGWDQGRCISIY--SSERSVLQSINPAEPHKECPNPKPDK-- 383
           C++YG  C  C ++RDPYC WD   C   +  +  R+  Q I   +P   C +   D   
Sbjct: 517 CDIYGKACAECCLARDPYCAWDGSACSRYFPTAKRRTRRQDIRNGDPLTHCSDLHHDNHH 576

Query: 384 --APLQKVSL-APNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCI-----LFI 435
             +P +++     NS  +L C  +S+ A   W+ +   E+  E      + I     L +
Sbjct: 577 GHSPEERIIYGVENSSTFLECSPKSQRALVYWQFQRRNEERKEEIRVDDHIIRTDQGLLL 636

Query: 436 ENLTAQQYGHYFCEAQEGSYFR 457
            +L  +  G+Y C A E  + +
Sbjct: 637 RSLQQKDSGNYLCHAVEHGFIQ 658


>gi|54607089 semaphorin 3B isoform 2 precursor [Homo sapiens]
          Length = 748

 Score =  203 bits (517), Expect = 3e-52
 Identities = 157/512 (30%), Positives = 231/512 (45%), Gaps = 44/512 (8%)

Query: 2   RGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTS---DTVMQNPQ 58
           +G +P+ P   +  +  G+E+YS +           FR +     L T       +  P+
Sbjct: 165 KGKSPYDPRHRAASVLVGEELYSGVAADLMGRDFTIFRSLGQRPSLRTEPHDSRWLNEPK 224

Query: 59  FIKAT-IVHQDQAYDDKIYYFFREDNPDKNPE-APLNVSRVAQLCRGDQGGESSLSVSKW 116
           F+K   I   +   DDKIY+FFRE   +  P    L+VSRV Q+CR D GG+ SL V+KW
Sbjct: 225 FVKVFWIPESENPDDDKIYFFFRETAVEAAPALGRLSVSRVGQICRNDVGGQRSL-VNKW 283

Query: 117 NTFLKAMLVCSDAAT--NKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNP--WNYSAVCVY 172
            TFLKA LVCS      + +F++LQDVFLL   S   R   +Y VFS    +  SAVCVY
Sbjct: 284 TTFLKARLVCSVPGVEGDTHFDQLQDVFLLS--SRDHRTPLLYAVFSTSSIFQGSAVCVY 341

Query: 173 SLGDIDKVFR---------TSSLKGYHSSLPNPRPGKC-------LPDQQPIPTETFQVA 216
           S+ D+ + F                Y   +P PRPG C           +  P +  Q A
Sbjct: 342 SMNDVRRAFLGPFAHKEGPMHQWVSYQGRVPYPRPGMCPSKTFGTFSSTKDFPDDVIQFA 401

Query: 217 DRHPEVAQRVEPMGPLKTPLF---HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHK 273
             HP +   V P G    PLF    + Y + ++A  R+ A+ G  + VL++ TD GT+ K
Sbjct: 402 RNHPLMYNSVLPTGG--RPLFLQVGANYTFTQIAADRVAAADGH-YDVLFIGTDVGTVLK 458

Query: 274 VVE--PGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVY 331
           V+    G +  +    + E+  F  +AA+ +M + ++R +LYV+S+  V+Q+ L  C  +
Sbjct: 459 VISVPKGSRPSAEGLLLEELHVFEDSAAVTSMQISSKRHQLYVASRSAVAQIALHRCAAH 518

Query: 332 GGGCHGCLMSRDPYCGWDQGRCISIYSS--ERSVLQSINPAEPHKECPNPKPDKAPLQ-K 388
           G  C  C ++RDPYC WD   C     S   R   Q +   +P   C       A L+ K
Sbjct: 519 GRVCTECCLARDPYCAWDGVACTRFQPSAKRRFRRQDVRNGDPSTLCSGDSSRPALLEHK 578

Query: 389 VSLAPNSRYYLSCPMESRHATYSWRHKE-----NVEQSCEPGHQSPNCILFIENLTAQQY 443
           V     S  +L C   S  A   W  +      + +   E   +     L +  L  +  
Sbjct: 579 VFGVEGSSAFLECEPRSLQARVEWTFQRAGVTAHTQVLAEERTERTARGLLLRRLRRRDS 638

Query: 444 GHYFCEAQEGSYFREAQHWQLLPEDGIMAEHL 475
           G Y C A E  + +  +   L       AE L
Sbjct: 639 GVYLCAAVEQGFTQPLRRLSLHVLSATQAERL 670


>gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens]
          Length = 749

 Score =  203 bits (516), Expect = 3e-52
 Identities = 157/513 (30%), Positives = 231/513 (45%), Gaps = 45/513 (8%)

Query: 2   RGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTS---DTVMQNPQ 58
           +G +P+ P   +  +  G+E+YS +           FR +     L T       +  P+
Sbjct: 165 KGKSPYDPRHRAASVLVGEELYSGVAADLMGRDFTIFRSLGQRPSLRTEPHDSRWLNEPK 224

Query: 59  FIKAT-IVHQDQAYDDKIYYFFREDNPDKNPE-APLNVSRVAQLCRGDQGGESSLSVSKW 116
           F+K   I   +   DDKIY+FFRE   +  P    L+VSRV Q+CR D GG+ SL V+KW
Sbjct: 225 FVKVFWIPESENPDDDKIYFFFRETAVEAAPALGRLSVSRVGQICRNDVGGQRSL-VNKW 283

Query: 117 NTFLKAMLVCSDAAT--NKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNP---WNYSAVCV 171
            TFLKA LVCS      + +F++LQDVFLL   S   R   +Y VFS     +  SAVCV
Sbjct: 284 TTFLKARLVCSVPGVEGDTHFDQLQDVFLLS--SRDHRTPLLYAVFSTSSSIFQGSAVCV 341

Query: 172 YSLGDIDKVFR---------TSSLKGYHSSLPNPRPGKC-------LPDQQPIPTETFQV 215
           YS+ D+ + F                Y   +P PRPG C           +  P +  Q 
Sbjct: 342 YSMNDVRRAFLGPFAHKEGPMHQWVSYQGRVPYPRPGMCPSKTFGTFSSTKDFPDDVIQF 401

Query: 216 ADRHPEVAQRVEPMGPLKTPLF---HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIH 272
           A  HP +   V P G    PLF    + Y + ++A  R+ A+ G  + VL++ TD GT+ 
Sbjct: 402 ARNHPLMYNSVLPTGG--RPLFLQVGANYTFTQIAADRVAAADGH-YDVLFIGTDVGTVL 458

Query: 273 KVVE--PGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEV 330
           KV+    G +  +    + E+  F  +AA+ +M + ++R +LYV+S+  V+Q+ L  C  
Sbjct: 459 KVISVPKGSRPSAEGLLLEELHVFEDSAAVTSMQISSKRHQLYVASRSAVAQIALHRCAA 518

Query: 331 YGGGCHGCLMSRDPYCGWDQGRCISIYSS--ERSVLQSINPAEPHKECPNPKPDKAPLQ- 387
           +G  C  C ++RDPYC WD   C     S   R   Q +   +P   C       A L+ 
Sbjct: 519 HGRVCTECCLARDPYCAWDGVACTRFQPSAKRRFRRQDVRNGDPSTLCSGDSSRPALLEH 578

Query: 388 KVSLAPNSRYYLSCPMESRHATYSWRHKE-----NVEQSCEPGHQSPNCILFIENLTAQQ 442
           KV     S  +L C   S  A   W  +      + +   E   +     L +  L  + 
Sbjct: 579 KVFGVEGSSAFLECEPRSLQARVEWTFQRAGVTAHTQVLAEERTERTARGLLLRRLRRRD 638

Query: 443 YGHYFCEAQEGSYFREAQHWQLLPEDGIMAEHL 475
            G Y C A E  + +  +   L       AE L
Sbjct: 639 SGVYLCAAVEQGFTQPLRRLSLHVLSATQAERL 671


>gi|188497703 semaphorin 3F [Homo sapiens]
          Length = 785

 Score =  194 bits (494), Expect = 1e-49
 Identities = 149/524 (28%), Positives = 240/524 (45%), Gaps = 57/524 (10%)

Query: 2   RGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYT---SDTVMQNPQ 58
           +G  P+ P  ++      +E+Y+ +           FR +  ++ + T   +   + +P 
Sbjct: 198 KGKCPYDPKLDTASALINEELYAGVYIDFMGTDAAIFRTLGKQTAMRTDQYNSRWLNDPS 257

Query: 59  FIKATIVHQD-QAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWN 117
           FI A ++    +  DDK+Y+FFRE + +  P++P   +R+ ++C  D GG   L V+KW+
Sbjct: 258 FIHAELIPDSAERNDDKLYFFFRERSAEA-PQSPAVYARIGRICLNDDGGHCCL-VNKWS 315

Query: 118 TFLKAMLVCS---DAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCV 171
           TFLKA LVCS   +     +F+ LQDVF+    +   R+  +Y VF++  +    SAVCV
Sbjct: 316 TFLKARLVCSVPGEDGIETHFDELQDVFV--QQTQDVRNPVIYAVFTSSGSVFRGSAVCV 373

Query: 172 YSLGDIDKVFR---------TSSLKGYHSSLPNPRPGKC--------LPDQQPIPTETFQ 214
           YS+ DI  VF                +   +P PRPG C        +   +  P E   
Sbjct: 374 YSMADIRMVFNGPFAHKEGPNYQWMPFSGKMPYPRPGTCPGGTFTPSMKSTKDYPDEVIN 433

Query: 215 VADRHPEVAQRVEPMGPLKTPLF---HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTI 271
               HP + Q V P+   + PL     + Y    +AV ++ A+ G  + VL+L TDRGT+
Sbjct: 434 FMRSHPLMYQAVYPLQ--RRPLVVRTGAPYRLTTIAVDQVDAADGR-YEVLFLGTDRGTV 490

Query: 272 HKVVE-PGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEV 330
            KV+  P + +      + E++ F+  A ++TM++ ++R++LYV+S   V+ + L  C+ 
Sbjct: 491 QKVIVLPKDDQELEELMLEEVEVFKDPAPVKTMTISSKRQQLYVASAVGVTHLSLHRCQA 550

Query: 331 YGGGCHGCLMSRDPYCGWDQGRC--ISIYSSERSVLQSINPAEPHKECP--NPKPDKAPL 386
           YG  C  C ++RDPYC WD   C   +  S  RS  Q +    P ++C   N   +K  +
Sbjct: 551 YGAACADCCLARDPYCAWDGQACSRYTASSKRRSRRQDVRHGNPIRQCRGFNSNANKNAV 610

Query: 387 QKVSL-APNSRYYLSCPMESRHATYSWRHKENV-----EQSCEPGHQSPNCILFIENLTA 440
           + V      S  +L C   S  AT  W  + +      E   E         L +  L  
Sbjct: 611 ESVQYGVAGSAAFLECQPRSPQATVKWLFQRDPGDRRREIRAEDRFLRTEQGLLLRALQL 670

Query: 441 QQYGHYFCEAQEGSYFREAQHWQLLPEDGIMAEHLLGHACALAA 484
              G Y C A E ++       QL         H+LG     AA
Sbjct: 671 SDRGLYSCTATENNFKHVVTRVQL---------HVLGRDAVHAA 705


>gi|41406086 semaphorin 3D [Homo sapiens]
          Length = 777

 Score =  180 bits (457), Expect = 2e-45
 Identities = 126/420 (30%), Positives = 207/420 (49%), Gaps = 40/420 (9%)

Query: 72  DDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCS---D 128
           DDKIY+FFRE + + +      +SRV ++C+ D GG+ SL ++KW TFLKA L+CS    
Sbjct: 257 DDKIYFFFRESSQEGSTSDKTILSRVGRVCKNDVGGQRSL-INKWTTFLKARLICSIPGS 315

Query: 129 AATNKNFNRLQDVFLLPDPSGQWRDTRVYGVF---SNPWNYSAVCVYSLGDIDKVFRTSS 185
              +  F+ LQD++LLP  +   R+  VYGVF   S+ +  SAVCVYS+ DI  VF    
Sbjct: 316 DGADTYFDELQDIYLLP--TRDERNPVVYGVFTTTSSIFKGSAVCVYSMADIRAVFNGPY 373

Query: 186 LKG---------YHSSLPNPRPGKC--------LPDQQPIPTETFQVADRHPEVAQRVEP 228
                       Y   +P PRPG C        +   +  P +      RH  + + V P
Sbjct: 374 AHKESADHRWVQYDGRIPYPRPGTCPSKTYDPLIKSTRDFPDDVISFIKRHSVMYKSVYP 433

Query: 229 MGPLKT-PLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFN 287
           +    T    +  Y   ++ V  + A  G+ + V++L TD GT+ KVV   +++ +    
Sbjct: 434 VAGGPTFKRINVDYRLTQIVVDHVIAEDGQ-YDVMFLGTDIGTVLKVVSISKEKWNMEEV 492

Query: 288 IME-IQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYC 346
           ++E +Q F+ ++ I  M L  ++++LY+ S+  + Q+ L  C+ YG  C  C ++RDPYC
Sbjct: 493 VLEELQIFKHSSIILNMELSLKQQQLYIGSRDGLVQLSLHRCDTYGKACADCCLARDPYC 552

Query: 347 GWDQGRC--ISIYSSERSVLQSINPAEPHKEC----PNPKPDKAPLQKVSLAPNSRYYLS 400
            WD   C   +  S  R+  Q +   +P  +C     +   + A  + +     +  +L 
Sbjct: 553 AWDGNACSRYAPTSKRRARRQDVKYGDPITQCWDIEDSISHETADEKVIFGIEFNSTFLE 612

Query: 401 CPMESRHATYSWRHKENVEQSCEPGHQSPNCI-----LFIENLTAQQYGHYFCEAQEGSY 455
           C  +S+ AT  W  + + ++  E        I     L I +L  +  G Y+C+AQE ++
Sbjct: 613 CIPKSQQATIKWYIQRSGDEHREELKPDERIIKTEYGLLIRSLQKKDSGMYYCKAQEHTF 672


>gi|6912650 semaphorin 3E [Homo sapiens]
          Length = 775

 Score =  178 bits (451), Expect = 1e-44
 Identities = 138/501 (27%), Positives = 227/501 (45%), Gaps = 53/501 (10%)

Query: 2   RGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTS---DTVMQNPQ 58
           RG  PF P  + +    G E+++ +    ++     FR +   + + T    + +++ P+
Sbjct: 167 RGRCPFDPSSSFISTLIGSELFAGLYSDYWSRDAAIFRSMGRLAHIRTEHDDERLLKEPK 226

Query: 59  FIKATIVHQDQAYDD-KIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWN 117
           F+ + ++  ++  DD K+Y+FF E   +    A    +RV +LC  D GG+  L V+KW+
Sbjct: 227 FVGSYMIPDNEDRDDNKVYFFFTEKALEAENNAHAIYTRVGRLCVNDVGGQRIL-VNKWS 285

Query: 118 TFLKAMLVCSDAATN---KNFNRLQDVFLLPDPSGQWRDTRVYGVF---SNPWNYSAVCV 171
           TFLKA LVCS    N     F+ L+DVFLLP  +   ++  ++G+F   SN +   A+CV
Sbjct: 286 TFLKARLVCSVPGMNGIDTYFDELEDVFLLP--TRDHKNPVIFGLFNTTSNIFRGHAICV 343

Query: 172 YSLGDIDKVFRT--SSLKG-------YHSSLPNPRPGKCLPD--------QQPIPTETFQ 214
           Y +  I   F    +  +G       Y   +P PRPG C            +  P +  +
Sbjct: 344 YHMSSIRAAFNGPYAHKEGPEYHWSVYEGKVPYPRPGSCASKVNGGRYGTTKDYPDDAIR 403

Query: 215 VADRHPEVAQRVEPMGPLKTPLF---HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTI 271
            A  HP + Q ++P    K P+      KY+ +++AV R++A  G+ + VL++ TD G +
Sbjct: 404 FARSHPLMYQAIKPAH--KKPILVKTDGKYNLKQIAVDRVEAEDGQ-YDVLFIGTDNGIV 460

Query: 272 HKVVEPGEQEHSFAFNIM--EIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCE 329
            KV+    QE      ++  E+Q F+    I +M + ++R++LY+ S   V+QV    C+
Sbjct: 461 LKVITIYNQEMESMEEVILEELQIFKDPVPIISMEISSKRQQLYIGSASAVAQVRFHHCD 520

Query: 330 VYGGGCHGCLMSRDPYCGWDQGRCISIY-----SSERSVLQSINPAEPHKEC-----PNP 379
           +YG  C  C ++RDPYC WD   C   Y     +  R   Q +      ++C        
Sbjct: 521 MYGSACADCCLARDPYCAWDGISCSRYYPTGTHAKRRFRRQDVRHGNAAQQCFGQQFVGD 580

Query: 380 KPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCI-----LF 434
             DK          N+   L C   S  A   W  ++  E   E        +     L 
Sbjct: 581 ALDKTEEHLAYGIENNSTLLECTPRSLQAKVIWFVQKGRETRKEEVKTDDRVVKMDLGLL 640

Query: 435 IENLTAQQYGHYFCEAQEGSY 455
              L     G YFC+  E S+
Sbjct: 641 FLRLHKSDAGTYFCQTVEHSF 661


>gi|214010218 semaphorin 4D isoform 1 [Homo sapiens]
          Length = 862

 Score =  170 bits (430), Expect = 3e-42
 Identities = 134/492 (27%), Positives = 221/492 (44%), Gaps = 57/492 (11%)

Query: 2   RGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTV--MQNPQF 59
           +G  PF P  +   +    E+YS      + G  P   R    S L T   +  +  P F
Sbjct: 153 KGRCPFDPAHSYTSVMVDGELYSGT-SYNFLGSEPIISRNSSHSPLRTEYAIPWLNEPSF 211

Query: 60  IKATIVHQD----QAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSK 115
           + A ++ +        DD++Y+FF E + +      + + R+A++C+GDQGG  +L   K
Sbjct: 212 VFADVIRKSPDSPDGEDDRVYFFFTEVSVEYEFVFRVLIPRIARVCKGDQGGLRTLQ-KK 270

Query: 116 WNTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFS---NPWNYSAVCVY 172
           W +FLKA L+CS   +   FN L+DVF+L  P    +    Y +F+   N    SAVC Y
Sbjct: 271 WTSFLKARLICSRPDSGLVFNVLRDVFVLRSPG--LKVPVFYALFTPQLNNVGLSAVCAY 328

Query: 173 SLGDIDKVFRTSSLK-------------GYHSSLPNPRPGKCLPDQQ---------PIPT 210
           +L   ++VF                    Y+  +P PRPG C+  +           +P 
Sbjct: 329 NLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNGPVPKPRPGACIDSEARAANYTSSLNLPD 388

Query: 211 ETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGT 270
           +T Q    HP +   V P+   +  L     +Y ++ V R QA  G  + V++++TDRG 
Sbjct: 389 KTLQFVKDHPLMDDSVTPIDN-RPRLIKKDVNYTQIVVDRTQALDGTVYDVMFVSTDRGA 447

Query: 271 IHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAER--RKLYVSSQWEVSQVPLDLC 328
           +HK +      H     I E Q F+    +QT+ L +++  R +Y  S   V Q PL  C
Sbjct: 448 LHKAISLEHAVHI----IEETQLFQDFEPVQTLLLSSKKGNRFVYAGSNSGVVQAPLAFC 503

Query: 329 EVYGGGCHGCLMSRDPYCGWD--QGRCISIYSSE---RSVLQSINPAEPHKECPNPKPDK 383
             + G C  C+++RDPYC W      C++++ +E   R ++Q +  +     CP+    K
Sbjct: 504 GKH-GTCEDCVLARDPYCAWSPPTATCVALHQTESPSRGLIQEM--SGDASVCPD--KSK 558

Query: 384 APLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPGH---QSPNCILFIENLTA 440
              ++          L C  +S  A   W+ +  V ++  P +      N ++F  NL+ 
Sbjct: 559 GSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPKYGLMGRKNLLIF--NLSE 616

Query: 441 QQYGHYFCEAQE 452
              G Y C ++E
Sbjct: 617 GDSGVYQCLSEE 628


>gi|9910362 semaphorin sem2 [Homo sapiens]
          Length = 782

 Score =  169 bits (427), Expect = 7e-42
 Identities = 142/490 (28%), Positives = 216/490 (44%), Gaps = 58/490 (11%)

Query: 2   RGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDT---VMQNPQ 58
           RG  P  P       F   E+Y+ +   ++ G+     R  G      SD+   ++ +P+
Sbjct: 167 RGRCPHEPSRPFASTFIDGELYTGLTA-DFLGREAMIFRSGGPRPALRSDSDQSLLHDPR 225

Query: 59  FIKATIVHQDQAYD-DKIYYFFREDNPDKNPEAPLN---VSRVAQLCRGDQGGESSLSVS 114
           F+ A  + ++   D DK+Y+FF E  P  +P+   N   VSRV ++C  D GG+  L V+
Sbjct: 226 FVMAARIPENSDQDNDKVYFFFSETVP--SPDGGSNHVTVSRVGRVCVNDAGGQRVL-VN 282

Query: 115 KWNTFLKAMLVCS---DAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNP---WNYSA 168
           KW+TFLKA LVCS         +F++L+DVFLL   +G  +   VY +FS     +   A
Sbjct: 283 KWSTFLKARLVCSVPGPGGAETHFDQLEDVFLLWPKAG--KSLEVYALFSTVSAVFQGFA 340

Query: 169 VCVYSLGDIDKVFR---------TSSLKGYHSSLPNPRPGKC-----------LPDQQPI 208
           VCVY + DI +VF                Y   +P PRPG C               +  
Sbjct: 341 VCVYHMADIWEVFNGPFAHRDGPQHQWGPYGGKVPFPRPGVCPSKMTAQPGRPFGSTKDY 400

Query: 209 PTETFQVADRHPEVAQRVEPM-GPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTD 267
           P E  Q A  HP +   V P  G       H      ++ V R++A  G T+ V++L TD
Sbjct: 401 PDEVLQFARAHPLMFWPVRPRHGRPVLVKTHLAQQLHQIVVDRVEAEDG-TYDVIFLGTD 459

Query: 268 RGTIHKVV--EPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPL 325
            G++ KV+  + G         + E+Q F+    I  M +  +R+ LYV S+  V+Q+ L
Sbjct: 460 SGSVLKVIALQAGGSAEPEEVVLEELQVFKVPTPITEMEISVKRQMLYVGSRLGVAQLRL 519

Query: 326 DLCEVYGGGCHGCLMSRDPYCGWDQGRCISIYSS---ERSVLQSINPAEPHKECPNPKPD 382
             CE YG  C  C ++RDPYC WD   C     S    R   Q I    P  +C     +
Sbjct: 520 HQCETYGTACAECCLARDPYCAWDGASCTHYRPSLGKRRFRRQDIRHGNPALQCLGQSQE 579

Query: 383 KAPLQKVSL-----APNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFIEN 437
           +  +  V+        ++  +L C  +S  A   W  +        PG + P+ +   E 
Sbjct: 580 EEAVGLVAATMVYGTEHNSTFLECLPKSPQAAVRWLLQ-------RPGDEGPDQVKTDER 632

Query: 438 LTAQQYGHYF 447
           +   + G  F
Sbjct: 633 VLHTERGLLF 642


>gi|214010220 semaphorin 4D isoform 2 [Homo sapiens]
          Length = 738

 Score =  166 bits (419), Expect = 6e-41
 Identities = 122/422 (28%), Positives = 194/422 (45%), Gaps = 54/422 (12%)

Query: 2   RGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTV--MQNPQF 59
           +G  PF P  +   +    E+YS      + G  P   R    S L T   +  +  P F
Sbjct: 153 KGRCPFDPAHSYTSVMVDGELYSGT-SYNFLGSEPIISRNSSHSPLRTEYAIPWLNEPSF 211

Query: 60  IKATIVHQD----QAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSK 115
           + A ++ +        DD++Y+FF E + +      + + R+A++C+GDQGG  +L   K
Sbjct: 212 VFADVIRKSPDSPDGEDDRVYFFFTEVSVEYEFVFRVLIPRIARVCKGDQGGLRTLQ-KK 270

Query: 116 WNTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFS---NPWNYSAVCVY 172
           W +FLKA L+CS   +   FN L+DVF+L  P    +    Y +F+   N    SAVC Y
Sbjct: 271 WTSFLKARLICSRPDSGLVFNVLRDVFVLRSPG--LKVPVFYALFTPQLNNVGLSAVCAY 328

Query: 173 SLGDIDKVFRTSSLK-------------GYHSSLPNPRPGKCLPDQQ---------PIPT 210
           +L   ++VF                    Y+  +P PRPG C+  +           +P 
Sbjct: 329 NLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNGPVPKPRPGACIDSEARAANYTSSLNLPD 388

Query: 211 ETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGT 270
           +T Q    HP +   V P+   +  L     +Y ++ V R QA  G  + V++++TDRG 
Sbjct: 389 KTLQFVKDHPLMDDSVTPIDN-RPRLIKKDVNYTQIVVDRTQALDGTVYDVMFVSTDRGA 447

Query: 271 IHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAER--RKLYVSSQWEVSQVPLDLC 328
           +HK +      H     I E Q F+    +QT+ L +++  R +Y  S   V Q PL  C
Sbjct: 448 LHKAISLEHAVHI----IEETQLFQDFEPVQTLLLSSKKGNRFVYAGSNSGVVQAPLAFC 503

Query: 329 EVYGGGCHGCLMSRDPYCGWD--QGRCISIYSSE---RSVLQ------SINPAEPHKECP 377
             + G C  C+++RDPYC W      C++++ +E   R ++Q      S+ PA   K  P
Sbjct: 504 GKH-GTCEDCVLARDPYCAWSPPTATCVALHQTESPSRGLIQEMSGDASVCPASSPKPLP 562

Query: 378 NP 379
            P
Sbjct: 563 PP 564


>gi|19923279 semaphorin W [Homo sapiens]
          Length = 770

 Score =  157 bits (398), Expect = 2e-38
 Identities = 149/537 (27%), Positives = 230/537 (42%), Gaps = 62/537 (11%)

Query: 2   RGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYT-SDTV---MQNP 57
           RG  PF P + S  +  G  +Y+   K  Y G  P   R  G +E +  +DT+   +  P
Sbjct: 167 RGKCPFEPAQRSAAVMAGGVLYAATVKN-YLGTEPIITRAVGRAEDWIRTDTLPSWLNAP 225

Query: 58  QFIKATIVHQ----DQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSV 113
            F+ A  +      D+  DD+IY+FF E +   +    + V RVA++C GD GG  +L  
Sbjct: 226 AFVAAVALSPAEWGDEDGDDEIYFFFTETSRAFDSYERIKVPRVARVCAGDLGGRKTLQ- 284

Query: 114 SKWNTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPW---NYSAVC 170
            +W TFLKA L+C      +  + LQDV +L    G       YG+FS+ W     SAVC
Sbjct: 285 QRWTTFLKADLLCPGPEHGRASSVLQDVAVLRPELGAGTPI-FYGIFSSQWEGATISAVC 343

Query: 171 VYSLGDIDKVFR----------TSSLKGYHSSLPNPRPGKCLPDQQ---------PIPTE 211
            +   DI  V               L    + +P PRPG+C+ +            +P  
Sbjct: 344 AFRPQDIRTVLNGPFRELKHDCNRGLPVVDNDVPQPRPGECITNNMKLRHFGSSLSLPDR 403

Query: 212 TFQVADRHPEVAQRVEPMG--PLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRG 269
                  HP + + V P    PL   L  +   Y +V  HR+ +  G+ + VLYL T+ G
Sbjct: 404 VLTFIRDHPLMDRPVFPADGHPL---LVTTDTAYLRVVAHRVTSLSGKEYDVLYLGTEDG 460

Query: 270 TIHKVVEPGEQEHSFAFNIME-IQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLC 328
            +H+ V  G Q      +++E +  F     ++ M L      L V S+ EV+QV    C
Sbjct: 461 HLHRAVRIGAQ-----LSVLEDLALFPEPQPVENMKL--YHSWLLVGSRTEVTQVNTTNC 513

Query: 329 EVYGGGCHGCLMSRDPYCGWD--QGRCISIYSSERSVLQSINPAEPHKECPNPKPDKAPL 386
                 C  C++++DP C W      C++     R ++Q I  A+    CP    ++  +
Sbjct: 514 GRL-QSCSECILAQDPVCAWSFRLDECVAHAGEHRGLVQDIESADVSSLCPKEPGERPVV 572

Query: 387 QKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFIENLTAQQYGHY 446
            +V +A  +   L C   S  A+  W H+ +   +  P       +     +T    G Y
Sbjct: 573 FEVPVATAAHVVLPCSPSSAWASCVW-HQPSGVTALTPRRDGLEVV-----VTPGAMGAY 626

Query: 447 FCEAQEGSYFREAQHWQLL---PEDGIMAEHLLGHACALAASLWLGVL-PTLTLGLL 499
            CE QEG        + L+     D     H +G   A  A  +LG+L  +LTL L+
Sbjct: 627 ACECQEGGAAHVVAAYSLVWGSQRDAPSRAHTVG---AGLAGFFLGILAASLTLILI 680


>gi|157388902 semaphorin 4C [Homo sapiens]
          Length = 833

 Score =  153 bits (387), Expect = 3e-37
 Identities = 130/489 (26%), Positives = 214/489 (43%), Gaps = 51/489 (10%)

Query: 2   RGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTV---MQNPQ 58
           +G  P+ P +    L    E+YS      + G  P   R  G      ++ +   +  P 
Sbjct: 156 KGKCPYDPAKGHAGLLVDGELYSATLNN-FLGTEPIILRNMGPHHSMKTEYLAFWLNEPH 214

Query: 59  FIKATIVHQDQAY----DDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVS 114
           F+ +  V +        DDK+Y+FFRE   + +  A   V+RVA++C+GD GG  +L   
Sbjct: 215 FVGSAYVPESVGSFTGDDDKVYFFFRERAVESDCYAEQVVARVARVCKGDMGGARTLQ-R 273

Query: 115 KWNTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWN---YSAVCV 171
           KW TFLKA L CS       FN+LQ +  L D S  W +T  +GVF   W     SA+C 
Sbjct: 274 KWTTFLKARLACSAPNWQLYFNQLQAMHTLQDTS--WHNTTFFGVFQAQWGDMYLSAICE 331

Query: 172 YSLGDIDKVFRTSSLKGYHSS----------LPNPRPGKCL---------PDQQPIPTET 212
           Y L +I +VF     K YH            +P+PRPG C+              +P   
Sbjct: 332 YQLEEIQRVFE-GPYKEYHEEAQKWDRYTDPVPSPRPGSCINNWHRRHGYTSSLELPDNI 390

Query: 213 FQVADRHPEVAQRVEPMGPLKTPLFHSK-YHYQKVAVHRMQASHGETFHVLYLTTDRGTI 271
                +HP + ++V P      PL   K  ++  +   R+    G T+ VL++ T  G +
Sbjct: 391 LNFVKKHPLMEEQVGPR--WSRPLLVKKGTNFTHLVADRVTGLDGATYTVLFIGTGDGWL 448

Query: 272 HKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVY 331
            K V  G   H     I E+Q F +   ++++ L   ++ L+  S+ ++ Q+P+  C  Y
Sbjct: 449 LKAVSLGPWVHL----IEELQLFDQ-EPMRSLVLSQSKKLLFAGSRSQLVQLPVADCMKY 503

Query: 332 GGGCHGCLMSRDPYCGW--DQGRCISIYSSERSVL-QSINPAEPHKEC--PNPKPDKAPL 386
              C  C+++RDPYC W  +  RC+++     S+L Q +  ++    C     K  +   
Sbjct: 504 -RSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQHVMTSDTSGICNLRGSKKVRPTP 562

Query: 387 QKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPG---HQSPNCILFIENLTAQQY 443
           + +++   +   L C + S  A   W        + +PG   + +    L +     +  
Sbjct: 563 KNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQPGSFLYDARLQALVVMAAQPRHA 622

Query: 444 GHYFCEAQE 452
           G Y C ++E
Sbjct: 623 GAYHCFSEE 631


>gi|21361914 semaphorin B [Homo sapiens]
          Length = 761

 Score =  152 bits (385), Expect = 5e-37
 Identities = 156/550 (28%), Positives = 235/550 (42%), Gaps = 79/550 (14%)

Query: 2   RGYAPFSP-DENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFI 60
           +G +PF P  +++ VL +G     T+    + G  P   R  G      S  V++   F+
Sbjct: 173 KGQSPFDPAHKHTAVLVDGMLYSGTMNN--FLGSEPILMRTLG------SQPVLKTDNFL 224

Query: 61  KATIVHQDQAY------DDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVS 114
           +   +H D ++         +Y+FF E   + +    L+ SRVA++C+ D GGE  L   
Sbjct: 225 RW--LHHDASFVAAIPSTQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGEKLLQ-K 281

Query: 115 KWNTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY-----SAV 169
           KW TFLKA L+C+       FN ++   LLP  S       +Y VF++ W       SAV
Sbjct: 282 KWTTFLKAQLLCTQPG-QLPFNVIRHAVLLPADSP--TAPHIYAVFTSQWQVGGTRSSAV 338

Query: 170 CVYSLGDIDKVFR---------TSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHP 220
           C +SL DI++VF+         TS    Y     NPRPG C     P   +       H 
Sbjct: 339 CAFSLLDIERVFKGKYKELNKETSRWTTYRGPETNPRPGSC--SVGPSSDKALTFMKDHF 396

Query: 221 EVAQRVEPMGPLKTPLF-HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGE 279
            + ++V     + TPL   S   Y ++AV   Q   G +  V+YL T  G++HK V  G+
Sbjct: 397 LMDEQV-----VGTPLLVKSGVEYTRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGD 451

Query: 280 QEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCL 339
              S A  + EIQ F     ++ + L   +  ++V     V +VP   C VY   C  C+
Sbjct: 452 ---SSAHLVEEIQLFPDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVY-ESCVDCV 507

Query: 340 MSRDPYCGWD---QGRCISIYSSERSVLQSINPAEPHKECPNP------KPDKAP--LQK 388
           ++RDP+C WD   +  C+    +  S  Q +    P   C +       +P   P  +++
Sbjct: 508 LARDPHCAWDPESRTCCLLSAPNLNSWKQDMERGNPEWACASGPMSRSLRPQSRPQIIKE 567

Query: 389 VSLAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFIENLTAQQYGHYFC 448
           V   PNS   L CP  S  A+Y W H             + + +L +++      G Y C
Sbjct: 568 VLAVPNSILELPCPHLSALASYYWSHGPAAVPEASSTVYNGSLLLIVQDGVG---GLYQC 624

Query: 449 EAQEG-------SYFREAQHWQLL--PE-DGIMAEHLL--------GHACALAASLWLGV 490
            A E        SY+ ++Q   L   PE  GI  EH+         G A A   S W   
Sbjct: 625 WATENGFSYPVISYWVDSQDQTLALDPELAGIPREHVKVPLTRVSGGAALAAQQSYWPHF 684

Query: 491 LPTLTLGLLV 500
           +    L  LV
Sbjct: 685 VTVTVLFALV 694


>gi|28872814 semaphorin 4G [Homo sapiens]
          Length = 843

 Score =  148 bits (373), Expect = 1e-35
 Identities = 134/493 (27%), Positives = 206/493 (41%), Gaps = 61/493 (12%)

Query: 6   PFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQ---NPQFIKA 62
           P+ P      L     +Y+  R +  +  IP  RR R    L T +T M    + +F+ +
Sbjct: 164 PYDPARGFTGLIIDGGLYTATRYEFRS--IPDIRRSRHPHSLRTEETPMHWLNDAEFVFS 221

Query: 63  TIVHQDQAY----DDKIYYFFREDNPDKNP------EAPLNVSRVAQLCRGDQGGESSLS 112
            +V + +A     DDK+YYFF E   ++         +   V+RVA++C+GD GG+  L 
Sbjct: 222 VLVRESKASAVGDDDKVYYFFTERATEEGSGSFTQSRSSHRVARVARVCKGDLGGKKILQ 281

Query: 113 VSKWNTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVF--SNPWNY---S 167
             KW +FLKA L+C        +  L+ V  L   +     T  Y  F  S  W     S
Sbjct: 282 -KKWTSFLKARLICHIPL----YETLRGVCSLDAETSS--RTHFYAAFTLSTQWKTLEAS 334

Query: 168 AVCVYSLGDIDKVFRTSSLK---------GYHSSLPNPRPGKCLPDQ---------QPIP 209
           A+C Y L +I  VF    ++          Y   +P PRPG C+ D          Q +P
Sbjct: 335 AICRYDLAEIQAVFAGPYMEYQDGSRRWGRYEGGVPEPRPGSCITDSLRSQGYNSSQDLP 394

Query: 210 TETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRG 269
           +        HP +A+ V P    +  L      Y  +    +    G T+ +L+L T  G
Sbjct: 395 SLVLDFVKLHPLMARPVVPTRG-RPLLLKRNIRYTHLTGTPVTTPAGPTYDLLFLGTADG 453

Query: 270 TIHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCE 329
            IHK V  G   H     I E Q FR + +++ + +   +  LYV +   V Q+PL  C 
Sbjct: 454 WIHKAVVLGSGMHI----IEETQVFRESQSVENLVISLLQHSLYVGAPSGVIQLPLSSCS 509

Query: 330 VYGGGCHGCLMSRDPYCGWDQG--RCISI-------YSSERSVLQSINPAEPHKECPNPK 380
            Y   C+ C+++RDPYCGWD G   C +          S  +++Q I       E     
Sbjct: 510 RYRS-CYDCILARDPYCGWDPGTHACAAATTIANRSQGSRTALIQDIERGNRGCESSRDT 568

Query: 381 PDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQS-CEPGHQSPNCILFIENLT 439
               PL+  S+       L C   S  A   W    ++  S  + G++     L + +  
Sbjct: 569 GPPPPLKTRSVLRGDDVLLPCDQPSNLARALWLLNGSMGLSDGQGGYRVGVDGLLVTDAQ 628

Query: 440 AQQYGHYFCEAQE 452
            +  G+Y C A+E
Sbjct: 629 PEHSGNYGCYAEE 641


>gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens]
          Length = 1011

 Score =  116 bits (291), Expect = 4e-26
 Identities = 107/386 (27%), Positives = 166/386 (43%), Gaps = 49/386 (12%)

Query: 6   PFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIV 65
           PF   + ++ LF   ++YS             +R +   S L T   +  + ++IK    
Sbjct: 167 PFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRT---IKYDSKWIKEPHF 223

Query: 66  HQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLV 125
                Y + +Y+FFRE   + N       SRVA++C+ D GG   +    W +FLKA L 
Sbjct: 224 LHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLN 283

Query: 126 CSDAATN-KNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF 181
           CS    +   F+ LQ +  +   +G      V GVF+   N    SAVC +S+ DI+KVF
Sbjct: 284 CSVPGDSFFYFDVLQSITDIIQING---IPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVF 340

Query: 182 --RTSSLKGYHS--------SLPNPRPGKC--------LPDQQPIPTETFQVADRHPEVA 223
             R    K   S         +P PRPG C               P ET      HP + 
Sbjct: 341 KGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMD 400

Query: 224 QRVEPMGPLKTPLF-HSKYHYQKVAVH-RMQASHGETFHVLYLTTDRGTIHKVVEPGEQE 281
             V P+     P F  ++  Y+  A+     A   + + V+++ ++ G + KV+    + 
Sbjct: 401 SAVPPIA--DEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVL---AKT 455

Query: 282 HSFAFN----IMEIQPFRRAAA---------IQTMSLDAERRKLYVSSQWEVSQVPLDLC 328
             F+ N    + EI+ +  A           + ++ LD +   LYV+    + ++PL  C
Sbjct: 456 SPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRC 515

Query: 329 EVYGGGCHGCLMSRDPYCGW-DQGRC 353
           E YG     C+ SRDPYCGW  QG C
Sbjct: 516 ERYGSCKKSCIASRDPYCGWLSQGSC 541


>gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens]
          Length = 597

 Score =  116 bits (291), Expect = 4e-26
 Identities = 107/386 (27%), Positives = 166/386 (43%), Gaps = 49/386 (12%)

Query: 6   PFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIV 65
           PF   + ++ LF   ++YS             +R +   S L T   +  + ++IK    
Sbjct: 167 PFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRT---IKYDSKWIKEPHF 223

Query: 66  HQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLV 125
                Y + +Y+FFRE   + N       SRVA++C+ D GG   +    W +FLKA L 
Sbjct: 224 LHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLN 283

Query: 126 CSDAATN-KNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF 181
           CS    +   F+ LQ +  +   +G      V GVF+   N    SAVC +S+ DI+KVF
Sbjct: 284 CSVPGDSFFYFDVLQSITDIIQING---IPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVF 340

Query: 182 --RTSSLKGYHS--------SLPNPRPGKC--------LPDQQPIPTETFQVADRHPEVA 223
             R    K   S         +P PRPG C               P ET      HP + 
Sbjct: 341 KGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMD 400

Query: 224 QRVEPMGPLKTPLF-HSKYHYQKVAVH-RMQASHGETFHVLYLTTDRGTIHKVVEPGEQE 281
             V P+     P F  ++  Y+  A+     A   + + V+++ ++ G + KV+    + 
Sbjct: 401 SAVPPIA--DEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVL---AKT 455

Query: 282 HSFAFN----IMEIQPFRRAAA---------IQTMSLDAERRKLYVSSQWEVSQVPLDLC 328
             F+ N    + EI+ +  A           + ++ LD +   LYV+    + ++PL  C
Sbjct: 456 SPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRC 515

Query: 329 EVYGGGCHGCLMSRDPYCGW-DQGRC 353
           E YG     C+ SRDPYCGW  QG C
Sbjct: 516 ERYGSCKKSCIASRDPYCGWLSQGSC 541


>gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]
          Length = 1073

 Score =  116 bits (291), Expect = 4e-26
 Identities = 107/386 (27%), Positives = 166/386 (43%), Gaps = 49/386 (12%)

Query: 6   PFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIV 65
           PF   + ++ LF   ++YS             +R +   S L T   +  + ++IK    
Sbjct: 167 PFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRT---IKYDSKWIKEPHF 223

Query: 66  HQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLV 125
                Y + +Y+FFRE   + N       SRVA++C+ D GG   +    W +FLKA L 
Sbjct: 224 LHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLN 283

Query: 126 CSDAATN-KNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF 181
           CS    +   F+ LQ +  +   +G      V GVF+   N    SAVC +S+ DI+KVF
Sbjct: 284 CSVPGDSFFYFDVLQSITDIIQING---IPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVF 340

Query: 182 --RTSSLKGYHS--------SLPNPRPGKC--------LPDQQPIPTETFQVADRHPEVA 223
             R    K   S         +P PRPG C               P ET      HP + 
Sbjct: 341 KGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMD 400

Query: 224 QRVEPMGPLKTPLF-HSKYHYQKVAVH-RMQASHGETFHVLYLTTDRGTIHKVVEPGEQE 281
             V P+     P F  ++  Y+  A+     A   + + V+++ ++ G + KV+    + 
Sbjct: 401 SAVPPIA--DEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVL---AKT 455

Query: 282 HSFAFN----IMEIQPFRRAAA---------IQTMSLDAERRKLYVSSQWEVSQVPLDLC 328
             F+ N    + EI+ +  A           + ++ LD +   LYV+    + ++PL  C
Sbjct: 456 SPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRC 515

Query: 329 EVYGGGCHGCLMSRDPYCGW-DQGRC 353
           E YG     C+ SRDPYCGW  QG C
Sbjct: 516 ERYGSCKKSCIASRDPYCGWLSQGSC 541


>gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]
          Length = 1017

 Score =  116 bits (291), Expect = 4e-26
 Identities = 107/386 (27%), Positives = 166/386 (43%), Gaps = 49/386 (12%)

Query: 6   PFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIV 65
           PF   + ++ LF   ++YS             +R +   S L T   +  + ++IK    
Sbjct: 167 PFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRT---IKYDSKWIKEPHF 223

Query: 66  HQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLV 125
                Y + +Y+FFRE   + N       SRVA++C+ D GG   +    W +FLKA L 
Sbjct: 224 LHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLN 283

Query: 126 CSDAATN-KNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF 181
           CS    +   F+ LQ +  +   +G      V GVF+   N    SAVC +S+ DI+KVF
Sbjct: 284 CSVPGDSFFYFDVLQSITDIIQING---IPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVF 340

Query: 182 --RTSSLKGYHS--------SLPNPRPGKC--------LPDQQPIPTETFQVADRHPEVA 223
             R    K   S         +P PRPG C               P ET      HP + 
Sbjct: 341 KGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMD 400

Query: 224 QRVEPMGPLKTPLF-HSKYHYQKVAVH-RMQASHGETFHVLYLTTDRGTIHKVVEPGEQE 281
             V P+     P F  ++  Y+  A+     A   + + V+++ ++ G + KV+    + 
Sbjct: 401 SAVPPIA--DEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVL---AKT 455

Query: 282 HSFAFN----IMEIQPFRRAAA---------IQTMSLDAERRKLYVSSQWEVSQVPLDLC 328
             F+ N    + EI+ +  A           + ++ LD +   LYV+    + ++PL  C
Sbjct: 456 SPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRC 515

Query: 329 EVYGGGCHGCLMSRDPYCGW-DQGRC 353
           E YG     C+ SRDPYCGW  QG C
Sbjct: 516 ERYGSCKKSCIASRDPYCGWLSQGSC 541


>gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens]
          Length = 998

 Score =  116 bits (291), Expect = 4e-26
 Identities = 107/386 (27%), Positives = 166/386 (43%), Gaps = 49/386 (12%)

Query: 6   PFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIV 65
           PF   + ++ LF   ++YS             +R +   S L T   +  + ++IK    
Sbjct: 167 PFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRT---IKYDSKWIKEPHF 223

Query: 66  HQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLV 125
                Y + +Y+FFRE   + N       SRVA++C+ D GG   +    W +FLKA L 
Sbjct: 224 LHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLN 283

Query: 126 CSDAATN-KNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF 181
           CS    +   F+ LQ +  +   +G      V GVF+   N    SAVC +S+ DI+KVF
Sbjct: 284 CSVPGDSFFYFDVLQSITDIIQING---IPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVF 340

Query: 182 --RTSSLKGYHS--------SLPNPRPGKC--------LPDQQPIPTETFQVADRHPEVA 223
             R    K   S         +P PRPG C               P ET      HP + 
Sbjct: 341 KGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMD 400

Query: 224 QRVEPMGPLKTPLF-HSKYHYQKVAVH-RMQASHGETFHVLYLTTDRGTIHKVVEPGEQE 281
             V P+     P F  ++  Y+  A+     A   + + V+++ ++ G + KV+    + 
Sbjct: 401 SAVPPIA--DEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVL---AKT 455

Query: 282 HSFAFN----IMEIQPFRRAAA---------IQTMSLDAERRKLYVSSQWEVSQVPLDLC 328
             F+ N    + EI+ +  A           + ++ LD +   LYV+    + ++PL  C
Sbjct: 456 SPFSLNDSVLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRC 515

Query: 329 EVYGGGCHGCLMSRDPYCGW-DQGRC 353
           E YG     C+ SRDPYCGW  QG C
Sbjct: 516 ERYGSCKKSCIASRDPYCGWLSQGSC 541


>gi|11991660 sema domain, transmembrane domain (TM), and cytoplasmic
           domain, (semaphorin) 6A [Homo sapiens]
          Length = 1030

 Score =  115 bits (287), Expect = 1e-25
 Identities = 115/394 (29%), Positives = 166/394 (42%), Gaps = 47/394 (11%)

Query: 6   PFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIV 65
           P+     ++ LF   ++YS             +R + GES   T  TV  + +++K    
Sbjct: 166 PYDAKHANVALFADGKLYSATVTDFLAIDAVIYRSL-GESP--TLRTVKHDSKWLKEPYF 222

Query: 66  HQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLV 125
            Q   Y D IY+FFRE   + N    +   RVAQ+C+ D GG   +   +W +FLKA L 
Sbjct: 223 VQAVDYGDYIYFFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLN 282

Query: 126 CS-DAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF 181
           CS    ++  FN LQ V  +   +G  RD  V   FS P+N    SAVC Y + DI  VF
Sbjct: 283 CSVPGDSHFYFNILQAVTDVIRING--RDV-VLATFSTPYNSIPGSAVCAYDMLDIASVF 339

Query: 182 --RTSSLKGYHSS--------LPNPRPGKC--------LPDQQPIPTETFQVADRHPEVA 223
             R    K   S+        +P PRPG C               P +T      HP + 
Sbjct: 340 TGRFKEQKSPDSTWTPVPDERVPKPRPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMD 399

Query: 224 QRVEPMGPLKTPLF---HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHK----VVE 276
           + V  +     P F     +Y   K+AV      + +   V++L +++G I K    +  
Sbjct: 400 EAVPSI--FNRPWFLRTMVRYRLTKIAVDTAAGPY-QNHTVVFLGSEKGIILKFLARIGN 456

Query: 277 PGEQEHSFAFNIMEIQPFRRAA-------AIQTMSLDAERRKLYVSSQWEVSQVPLDLCE 329
            G    S     M +    + +        I  M LD     LYV+    V +VPL  CE
Sbjct: 457 SGFLNDSLFLEEMSVYNSEKCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCE 516

Query: 330 VYGGGCHGCLMSRDPYCGW--DQGRCISIYSSER 361
            +G     C+ SRDPYCGW  + G C  +  + R
Sbjct: 517 RHGKCKKTCIASRDPYCGWIKEGGACSHLSPNSR 550


>gi|16306552 semaphorin Y [Homo sapiens]
          Length = 930

 Score =  113 bits (282), Expect = 5e-25
 Identities = 103/392 (26%), Positives = 163/392 (41%), Gaps = 48/392 (12%)

Query: 6   PFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTS---DTVMQNPQFIKA 62
           PF   ++++ +F    +YS             +R +  +  L ++      ++ P F++A
Sbjct: 170 PFDATQSNVAIFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQA 229

Query: 63  TIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKA 122
                   + D +Y+FFRE + +      +  SRVA++C+ D GG        W +FLK 
Sbjct: 230 L------EHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKL 283

Query: 123 MLVCSDAATNK-NFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDID 178
            L CS    +   F+ LQ    L  P      + ++GVF+   N    SAVC + L +I+
Sbjct: 284 RLNCSVPGDSTFYFDVLQ---ALTGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEIE 340

Query: 179 KVFRTS-----SLKGY-----HSSLPNPRPGKC--------LPDQQPIPTETFQVADRHP 220
           + F        SL G         +P+PRPG C            + +P +       HP
Sbjct: 341 RGFEGKFKEQRSLDGAWTPVSEDRVPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHP 400

Query: 221 EVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQ 280
            +   V P+         S+    +VAV  M   H     V++L ++ GT+ KV+ PG +
Sbjct: 401 LLDPAVPPVTHQPLLTLTSRALLTQVAVDGMAGPHSN-ITVMFLGSNDGTVLKVLTPGGR 459

Query: 281 ----EHSFAFNIMEIQPFR--------RAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLC 328
               E      I    P R         A  I  + LD E  +L+V+    +  +PL  C
Sbjct: 460 SGGPEPILLEEIDAYSPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRC 519

Query: 329 EVYGGGCHGCLMSRDPYCGWDQGR-CISIYSS 359
             +G     CL S+DPYCGW   R C+ I  S
Sbjct: 520 ARHGACQRSCLASQDPYCGWHSSRGCVDIRGS 551


>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
          Length = 1151

 Score =  112 bits (281), Expect = 6e-25
 Identities = 107/387 (27%), Positives = 169/387 (43%), Gaps = 43/387 (11%)

Query: 6   PFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGE-----SELYTSDTVMQNPQFI 60
           P+ P  NS  +             +++G+ P   R  G      +  Y S   +  P F+
Sbjct: 230 PYDPRHNSTAVISSQGELYAATVIDFSGRDPAIYRSLGSGPPLRTAQYNSKW-LNEPNFV 288

Query: 61  KATIVHQDQAYDDKIY-YFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTF 119
            A        YD  ++ YFF  +N  ++       SRVA++C+ D GG   L    W TF
Sbjct: 289 AA--------YDIGLFAYFFLRENAVEHDCGRTVYSRVARVCKNDVGGRFLLE-DTWTTF 339

Query: 120 LKAMLVCS-DAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLG 175
           +KA L CS        +N LQ  F LP+         +YGVF+   N    SAVC ++L 
Sbjct: 340 MKARLNCSRPGEVPFYYNELQSAFHLPEQD------LIYGVFTTNVNSIAASAVCAFNLS 393

Query: 176 DIDKVFR-----TSSLKGYHSSLPNPRPG-KC--LPDQQP---IPTETFQVADRHPEVAQ 224
            I + F        + +     + NP P  +C  LP+  P   +   + Q A R   +++
Sbjct: 394 AISQAFNGPFRYQENPRAAWLPIANPIPNFQCGTLPETGPNENLTERSLQDAQRLFLMSE 453

Query: 225 RVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQE-HS 283
            V+P+ P +  +      +  + V  +QA     +HVLY+ T+ GTI K +    +  H 
Sbjct: 454 AVQPVTP-EPCVTQDSVRFSHLVVDLVQAKD-TLYHVLYIGTESGTILKALSTASRSLHG 511

Query: 284 FAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRD 343
                + + P  R   ++++ +    R L+V  +  V +VPL+ C  Y      CL +RD
Sbjct: 512 CYLEELHVLPPGRREPLRSLRILHSARALFVGLRDGVLRVPLERCAAYRSQ-GACLGARD 570

Query: 344 PYCGWD--QGRCISIYSSERSVLQSIN 368
           PYCGWD  Q RC ++  S    L + N
Sbjct: 571 PYCGWDGKQQRCSTLEDSSNMSLWTQN 597


>gi|147904700 semaphorin 5A [Homo sapiens]
          Length = 1074

 Score =  110 bits (276), Expect = 2e-24
 Identities = 112/375 (29%), Positives = 169/375 (45%), Gaps = 38/375 (10%)

Query: 6   PFSPDENSLVLFE-GDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATI 64
           P+SP  NS  L   G E+Y+     ++ G+ P   R  G   L    T   N +++    
Sbjct: 162 PYSPQHNSTALLTAGGELYAATA-MDFPGRDPAIYRSLGI--LPPLRTAQYNSKWLNEPN 218

Query: 65  VHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAML 124
                   +  Y+FFRE N  ++       SR A++C+ D GG   L    W TF+KA L
Sbjct: 219 FVSSYDIGNFTYFFFRE-NAVEHDCGKTVFSRAARVCKNDIGGRFLLE-DTWTTFMKARL 276

Query: 125 VCS-DAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKV 180
            CS        +N LQ  F LP+         +YG+F+   N    SAVCV++L  I + 
Sbjct: 277 NCSRPGEVPFYYNELQSTFFLPELD------LIYGIFTTNVNSIAASAVCVFNLSAIAQA 330

Query: 181 FRTSSLKGYHSS------LPNPRPG-KCLPDQQPIPTETFQVADRHPEVAQRV----EPM 229
           F +   K   +S       PNP P  +C    Q +      + +R+ + AQ+     E +
Sbjct: 331 F-SGPFKYQENSRSAWLPYPNPNPHFQCGTVDQGLYVN---LTERNLQDAQKFILMHEVV 386

Query: 230 GPLKT-PLF-HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAF- 286
            P+ T P F      +  VAV  +Q       H++YL TD GTI KV  P  Q  S    
Sbjct: 387 QPVTTVPSFMEDNSRFSHVAVDVVQGREA-LVHIIYLATDYGTIKKVRVPLNQTSSSCLL 445

Query: 287 NIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYC 346
             +E+ P RR   I+++ +   +  L+V  +  V ++PL  C+ Y      C+ ++DPYC
Sbjct: 446 EEIELFPERRREPIRSLQILHSQSVLFVGLREHVVKIPLKRCQFYRTRST-CIGAQDPYC 504

Query: 347 GWD--QGRCISIYSS 359
           GWD    +C S+  S
Sbjct: 505 GWDVVMKKCTSLEES 519


>gi|19718780 semaphorin 6B precursor [Homo sapiens]
          Length = 888

 Score = 98.6 bits (244), Expect = 1e-20
 Identities = 103/373 (27%), Positives = 158/373 (42%), Gaps = 59/373 (15%)

Query: 33  GKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQDQAYDDKIYYFFREDNPDKNPEAPL 92
           G  P  R ++ +S+ +      + P F+ A        +   +Y+FFRE   + N    +
Sbjct: 211 GDRPTLRTVKHDSKWF------KEPYFVHAV------EWGSHVYFFFREIAMEFNYLEKV 258

Query: 93  NVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCS-DAATNKNFNRLQDVFLLPDPSGQW 151
            VSRVA++C+ D GG   +   +W +FLKA L CS    ++  FN LQ V  +    G+ 
Sbjct: 259 VVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSVPGDSHFYFNVLQAVTGVVSLGGR- 317

Query: 152 RDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF--RTSSLKGYHS--------SLPNPRP 198
               V  VFS P N    SAVC + L  +  VF  R    K   S         +P PRP
Sbjct: 318 --PVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFEGRFREQKSPESIWTPVPEDQVPRPRP 375

Query: 199 GKC-LPDQQ-----PIPTETFQVADRHPEVAQRVEPMGP----LKTPLFHSKYHYQKVAV 248
           G C  P  Q      +P +       HP + + V  +G     L+T + H      +VAV
Sbjct: 376 GCCAAPGMQYNASSALPDDILNFVKTHPLMDEAVPSLGHAPWILRTLMRH---QLTRVAV 432

Query: 249 HRMQASHGETFHVLYLTTDRGTIHK-VVEPGEQ---EHSFAFNIMEIQPFR--------- 295
                  G    V++L ++ GT+ K +V P          +  + E + +R         
Sbjct: 433 DVGAGPWGNQ-TVVFLGSEAGTVLKFLVRPNASTSGTSGLSVFLEEFETYRPDRCGRPGG 491

Query: 296 --RAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGW-DQGR 352
                 + ++ LDA    L  +    V +VP+  C+ Y G    C+ S+DPYCGW   G 
Sbjct: 492 GETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYSGCMKNCIGSQDPYCGWAPDGS 551

Query: 353 CISIYSSERSVLQ 365
           CI +    R+  +
Sbjct: 552 CIFLSPGTRAAFE 564


>gi|24234732 semaphorin 6D isoform 6 precursor [Homo sapiens]
          Length = 476

 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 79/294 (26%), Positives = 124/294 (42%), Gaps = 32/294 (10%)

Query: 6   PFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIV 65
           PF   + ++ LF   ++YS             +R +   S L T   +  + ++IK    
Sbjct: 167 PFDARQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRT---IKYDSKWIKEPHF 223

Query: 66  HQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLV 125
                Y + +Y+FFRE   + N       SRVA++C+ D GG   +    W +FLKA L 
Sbjct: 224 LHAIEYGNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLN 283

Query: 126 CSDAATN-KNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF 181
           CS    +   F+ LQ +  +   +G      V GVF+   N    SAVC +S+ DI+KVF
Sbjct: 284 CSVPGDSFFYFDVLQSITDIIQING---IPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVF 340

Query: 182 --RTSSLKGYHS--------SLPNPRPGKC--------LPDQQPIPTETFQVADRHPEVA 223
             R    K   S         +P PRPG C               P ET      HP + 
Sbjct: 341 KGRFKEQKTPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMD 400

Query: 224 QRVEPMGPLKTPLF-HSKYHYQKVAVH-RMQASHGETFHVLYLTTDRGTIHKVV 275
             V P+     P F  ++  Y+  A+     A   + + V+++ ++ G + KV+
Sbjct: 401 SAVPPIA--DEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVL 452


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.426 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,825,820
Number of Sequences: 37866
Number of extensions: 1054952
Number of successful extensions: 3136
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 42
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 2921
Number of HSP's gapped (non-prelim): 99
length of query: 501
length of database: 18,247,518
effective HSP length: 106
effective length of query: 395
effective length of database: 14,233,722
effective search space: 5622320190
effective search space used: 5622320190
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.