Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 225637520
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo
sapiens]
(652 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens] 1368 0.0
gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens] 1359 0.0
gi|225637524 semaphorin 7A isoform 3 [Homo sapiens] 1053 0.0
gi|39777610 semaphorin 4B precursor [Homo sapiens] 228 1e-59
gi|39777608 semaphorin 4B precursor [Homo sapiens] 228 1e-59
gi|5174673 semaphorin 3A precursor [Homo sapiens] 226 4e-59
gi|54607089 semaphorin 3B isoform 2 precursor [Homo sapiens] 220 3e-57
gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens] 220 4e-57
gi|5454048 semaphorin 3C [Homo sapiens] 212 1e-54
gi|188497703 semaphorin 3F [Homo sapiens] 197 3e-50
gi|214010218 semaphorin 4D isoform 1 [Homo sapiens] 194 2e-49
gi|41406086 semaphorin 3D [Homo sapiens] 194 3e-49
gi|6912650 semaphorin 3E [Homo sapiens] 193 5e-49
gi|214010220 semaphorin 4D isoform 2 [Homo sapiens] 190 4e-48
gi|9910362 semaphorin sem2 [Homo sapiens] 183 4e-46
gi|19923279 semaphorin W [Homo sapiens] 180 4e-45
gi|28872814 semaphorin 4G [Homo sapiens] 170 3e-42
gi|157388902 semaphorin 4C [Homo sapiens] 167 2e-41
gi|21361914 semaphorin B [Homo sapiens] 166 6e-41
gi|11991660 sema domain, transmembrane domain (TM), and cytoplas... 145 9e-35
gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens] 133 4e-31
gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens] 133 4e-31
gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens] 133 4e-31
gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens] 133 4e-31
gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens] 133 4e-31
gi|147904700 semaphorin 5A [Homo sapiens] 132 1e-30
gi|16306552 semaphorin Y [Homo sapiens] 131 2e-30
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens] 130 3e-30
gi|19718780 semaphorin 6B precursor [Homo sapiens] 122 1e-27
gi|24234732 semaphorin 6D isoform 6 precursor [Homo sapiens] 95 2e-19
>gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens]
Length = 652
Score = 1368 bits (3542), Expect = 0.0
Identities = 652/652 (100%), Positives = 652/652 (100%)
Query: 1 MTPPPPGRAAPSAPRARVPGPPARLGLPLRLRLLLLLWAAAASAQGHLRSGPRIFAVWKG 60
MTPPPPGRAAPSAPRARVPGPPARLGLPLRLRLLLLLWAAAASAQGHLRSGPRIFAVWKG
Sbjct: 1 MTPPPPGRAAPSAPRARVPGPPARLGLPLRLRLLLLLWAAAASAQGHLRSGPRIFAVWKG 60
Query: 61 HVGQDRVDFGQTEPHTVLFHEPGSSSVWVGGRGKVYLFDFPEGKNASVRTDCENYITLLE 120
HVGQDRVDFGQTEPHTVLFHEPGSSSVWVGGRGKVYLFDFPEGKNASVRTDCENYITLLE
Sbjct: 61 HVGQDRVDFGQTEPHTVLFHEPGSSSVWVGGRGKVYLFDFPEGKNASVRTDCENYITLLE 120
Query: 121 RRSEGLLACGTNARHPSCWNLVNGTVVPLGEMRGYAPFSPDENSLVLFEGDEVYSTIRKQ 180
RRSEGLLACGTNARHPSCWNLVNGTVVPLGEMRGYAPFSPDENSLVLFEGDEVYSTIRKQ
Sbjct: 121 RRSEGLLACGTNARHPSCWNLVNGTVVPLGEMRGYAPFSPDENSLVLFEGDEVYSTIRKQ 180
Query: 181 EYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQDQAYDDKIYYFFREDNPDKNPE 240
EYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQDQAYDDKIYYFFREDNPDKNPE
Sbjct: 181 EYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQDQAYDDKIYYFFREDNPDKNPE 240
Query: 241 APLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSG 300
APLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSG
Sbjct: 241 APLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSG 300
Query: 301 QWRDTRVYGVFSNPWNYSAVCVYSLGDIDKVFRTSSLKGYHSSLPNPRPGKCLPDQQPIP 360
QWRDTRVYGVFSNPWNYSAVCVYSLGDIDKVFRTSSLKGYHSSLPNPRPGKCLPDQQPIP
Sbjct: 301 QWRDTRVYGVFSNPWNYSAVCVYSLGDIDKVFRTSSLKGYHSSLPNPRPGKCLPDQQPIP 360
Query: 361 TETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRG 420
TETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRG
Sbjct: 361 TETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRG 420
Query: 421 TIHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCE 480
TIHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCE
Sbjct: 421 TIHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCE 480
Query: 481 VYGGGCHGCLMSRDPYCGWDQGRCISIYSSERSVLQSINPAEPHKECPNPKPDKAPLQKV 540
VYGGGCHGCLMSRDPYCGWDQGRCISIYSSERSVLQSINPAEPHKECPNPKPDKAPLQKV
Sbjct: 481 VYGGGCHGCLMSRDPYCGWDQGRCISIYSSERSVLQSINPAEPHKECPNPKPDKAPLQKV 540
Query: 541 SLAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFIENLTAQQYGHYFCE 600
SLAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFIENLTAQQYGHYFCE
Sbjct: 541 SLAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFIENLTAQQYGHYFCE 600
Query: 601 AQEGSYFREAQHWQLLPEDGIMAEHLLGHACALAASLWLGVLPTLTLGLLVH 652
AQEGSYFREAQHWQLLPEDGIMAEHLLGHACALAASLWLGVLPTLTLGLLVH
Sbjct: 601 AQEGSYFREAQHWQLLPEDGIMAEHLLGHACALAASLWLGVLPTLTLGLLVH 652
>gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens]
Length = 666
Score = 1359 bits (3517), Expect = 0.0
Identities = 652/666 (97%), Positives = 652/666 (97%), Gaps = 14/666 (2%)
Query: 1 MTPPPPGRAAPSAPRARVPGPPARLGLPLRLRLLLLLWAAAASAQGHLRSGPRIFAVWKG 60
MTPPPPGRAAPSAPRARVPGPPARLGLPLRLRLLLLLWAAAASAQGHLRSGPRIFAVWKG
Sbjct: 1 MTPPPPGRAAPSAPRARVPGPPARLGLPLRLRLLLLLWAAAASAQGHLRSGPRIFAVWKG 60
Query: 61 HVGQDRVDFGQTEPHTVLFHEPGSSSVWVGGRGKVYLFDFPEGKNASVRT---------- 110
HVGQDRVDFGQTEPHTVLFHEPGSSSVWVGGRGKVYLFDFPEGKNASVRT
Sbjct: 61 HVGQDRVDFGQTEPHTVLFHEPGSSSVWVGGRGKVYLFDFPEGKNASVRTVNIGSTKGSC 120
Query: 111 ----DCENYITLLERRSEGLLACGTNARHPSCWNLVNGTVVPLGEMRGYAPFSPDENSLV 166
DCENYITLLERRSEGLLACGTNARHPSCWNLVNGTVVPLGEMRGYAPFSPDENSLV
Sbjct: 121 LDKRDCENYITLLERRSEGLLACGTNARHPSCWNLVNGTVVPLGEMRGYAPFSPDENSLV 180
Query: 167 LFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQDQAYDDKI 226
LFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQDQAYDDKI
Sbjct: 181 LFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQDQAYDDKI 240
Query: 227 YYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATNKNF 286
YYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATNKNF
Sbjct: 241 YYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATNKNF 300
Query: 287 NRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDKVFRTSSLKGYHSSLPN 346
NRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDKVFRTSSLKGYHSSLPN
Sbjct: 301 NRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDKVFRTSSLKGYHSSLPN 360
Query: 347 PRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASH 406
PRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASH
Sbjct: 361 PRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASH 420
Query: 407 GETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVS 466
GETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVS
Sbjct: 421 GETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVS 480
Query: 467 SQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQGRCISIYSSERSVLQSINPAEPHKE 526
SQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQGRCISIYSSERSVLQSINPAEPHKE
Sbjct: 481 SQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQGRCISIYSSERSVLQSINPAEPHKE 540
Query: 527 CPNPKPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFI 586
CPNPKPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFI
Sbjct: 541 CPNPKPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFI 600
Query: 587 ENLTAQQYGHYFCEAQEGSYFREAQHWQLLPEDGIMAEHLLGHACALAASLWLGVLPTLT 646
ENLTAQQYGHYFCEAQEGSYFREAQHWQLLPEDGIMAEHLLGHACALAASLWLGVLPTLT
Sbjct: 601 ENLTAQQYGHYFCEAQEGSYFREAQHWQLLPEDGIMAEHLLGHACALAASLWLGVLPTLT 660
Query: 647 LGLLVH 652
LGLLVH
Sbjct: 661 LGLLVH 666
>gi|225637524 semaphorin 7A isoform 3 [Homo sapiens]
Length = 501
Score = 1053 bits (2724), Expect = 0.0
Identities = 501/501 (100%), Positives = 501/501 (100%)
Query: 152 MRGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFI 211
MRGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFI
Sbjct: 1 MRGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFI 60
Query: 212 KATIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFL 271
KATIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFL
Sbjct: 61 KATIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFL 120
Query: 272 KAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDKV 331
KAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDKV
Sbjct: 121 KAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNYSAVCVYSLGDIDKV 180
Query: 332 FRTSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSK 391
FRTSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSK
Sbjct: 181 FRTSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSK 240
Query: 392 YHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAI 451
YHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAI
Sbjct: 241 YHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAI 300
Query: 452 QTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQGRCISIYSSE 511
QTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQGRCISIYSSE
Sbjct: 301 QTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQGRCISIYSSE 360
Query: 512 RSVLQSINPAEPHKECPNPKPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQ 571
RSVLQSINPAEPHKECPNPKPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQ
Sbjct: 361 RSVLQSINPAEPHKECPNPKPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQ 420
Query: 572 SCEPGHQSPNCILFIENLTAQQYGHYFCEAQEGSYFREAQHWQLLPEDGIMAEHLLGHAC 631
SCEPGHQSPNCILFIENLTAQQYGHYFCEAQEGSYFREAQHWQLLPEDGIMAEHLLGHAC
Sbjct: 421 SCEPGHQSPNCILFIENLTAQQYGHYFCEAQEGSYFREAQHWQLLPEDGIMAEHLLGHAC 480
Query: 632 ALAASLWLGVLPTLTLGLLVH 652
ALAASLWLGVLPTLTLGLLVH
Sbjct: 481 ALAASLWLGVLPTLTLGLLVH 501
>gi|39777610 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 228 bits (581), Expect = 1e-59
Identities = 182/570 (31%), Positives = 262/570 (45%), Gaps = 65/570 (11%)
Query: 104 KNASVRTDCENYIT-LLERRSEGLLACGTNARHPSCW--NLVNGTV-------VPLGEMR 153
K + DC+NYI LL L CGT A P C N+ N T+ V L + +
Sbjct: 123 KGKDPQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLEDGK 182
Query: 154 GYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTV--MQNPQFI 211
G PF P+ S L E+Y T + G P R + T ++ +Q+P F+
Sbjct: 183 GRCPFDPNFKSTALVVDGELY-TGTVSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAFV 241
Query: 212 KATIVHQD----QAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKW 267
+ + + Q DDKIY+FF E + VSR+A++C+GD+GGE L +W
Sbjct: 242 ASAYIPESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQ-QRW 300
Query: 268 NTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY-----SAVCV 322
+FLKA L+CS FN LQDVF L WRDT YGVF++ W+ SAVCV
Sbjct: 301 TSFLKAQLLCSRPDDGFPFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCV 360
Query: 323 YSLGDIDKVF---------RTSSLKGYHSSLPNPRPGKCLPD--QQPIPTETFQVADRHP 371
+++ D+ +VF T +P PRPG C+ + ++ + Q+ DR
Sbjct: 361 FTMKDVQRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRVL 420
Query: 372 EVAQ---RVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEP 428
+ ++ + L + YQ+VAVHR+ H T+ VL+L T G +HK V
Sbjct: 421 NFLKDHFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLH-HTYDVLFLGTGDGRLHKAVSV 479
Query: 429 GEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHG 488
G + H I E+Q F +Q + LD R LY +S V QVP+ C +Y C
Sbjct: 480 GPRVHI----IEELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLY-RSCGD 534
Query: 489 CLMSRDPYCGWDQGRC--ISIYSSE---RSVLQSINPAEPHKEC-------PNPKP-DKA 535
CL++RDPYC W C +S+Y + R +Q I A C P+ P +
Sbjct: 535 CLLARDPYCAWSGSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSASSVVSPSFVPTGEK 594
Query: 536 PLQKVSLAPNSRYYLSCPMESRHATYSWRHK---ENVEQSCEPGHQSPNCILFIENLTAQ 592
P ++V PN+ L+CP+ S AT W N SC H P L + + Q
Sbjct: 595 PCEQVQFQPNTVNTLACPLLSNLATRLWLRNGAPVNASASC---HVLPTGDLLL--VGTQ 649
Query: 593 QYGHYFC-EAQEGSYFREAQHWQLLPEDGI 621
Q G + C +EG A + + EDG+
Sbjct: 650 QLGEFQCWSLEEGFQQLVASYCPEVVEDGV 679
>gi|39777608 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 228 bits (581), Expect = 1e-59
Identities = 182/570 (31%), Positives = 262/570 (45%), Gaps = 65/570 (11%)
Query: 104 KNASVRTDCENYIT-LLERRSEGLLACGTNARHPSCW--NLVNGTV-------VPLGEMR 153
K + DC+NYI LL L CGT A P C N+ N T+ V L + +
Sbjct: 123 KGKDPQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLEDGK 182
Query: 154 GYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTV--MQNPQFI 211
G PF P+ S L E+Y T + G P R + T ++ +Q+P F+
Sbjct: 183 GRCPFDPNFKSTALVVDGELY-TGTVSSFQGNDPAISRSQSLRPTKTESSLNWLQDPAFV 241
Query: 212 KATIVHQD----QAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKW 267
+ + + Q DDKIY+FF E + VSR+A++C+GD+GGE L +W
Sbjct: 242 ASAYIPESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQ-QRW 300
Query: 268 NTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY-----SAVCV 322
+FLKA L+CS FN LQDVF L WRDT YGVF++ W+ SAVCV
Sbjct: 301 TSFLKAQLLCSRPDDGFPFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCV 360
Query: 323 YSLGDIDKVF---------RTSSLKGYHSSLPNPRPGKCLPD--QQPIPTETFQVADRHP 371
+++ D+ +VF T +P PRPG C+ + ++ + Q+ DR
Sbjct: 361 FTMKDVQRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRVL 420
Query: 372 EVAQ---RVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEP 428
+ ++ + L + YQ+VAVHR+ H T+ VL+L T G +HK V
Sbjct: 421 NFLKDHFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLH-HTYDVLFLGTGDGRLHKAVSV 479
Query: 429 GEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHG 488
G + H I E+Q F +Q + LD R LY +S V QVP+ C +Y C
Sbjct: 480 GPRVHI----IEELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLY-RSCGD 534
Query: 489 CLMSRDPYCGWDQGRC--ISIYSSE---RSVLQSINPAEPHKEC-------PNPKP-DKA 535
CL++RDPYC W C +S+Y + R +Q I A C P+ P +
Sbjct: 535 CLLARDPYCAWSGSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSASSVVSPSFVPTGEK 594
Query: 536 PLQKVSLAPNSRYYLSCPMESRHATYSWRHK---ENVEQSCEPGHQSPNCILFIENLTAQ 592
P ++V PN+ L+CP+ S AT W N SC H P L + + Q
Sbjct: 595 PCEQVQFQPNTVNTLACPLLSNLATRLWLRNGAPVNASASC---HVLPTGDLLL--VGTQ 649
Query: 593 QYGHYFC-EAQEGSYFREAQHWQLLPEDGI 621
Q G + C +EG A + + EDG+
Sbjct: 650 QLGEFQCWSLEEGFQQLVASYCPEVVEDGV 679
>gi|5174673 semaphorin 3A precursor [Homo sapiens]
Length = 771
Score = 226 bits (577), Expect = 4e-59
Identities = 186/663 (28%), Positives = 298/663 (44%), Gaps = 96/663 (14%)
Query: 32 RLLLLLWAAAASAQGHLRSG----PRIFAVWKGHVGQDRVDF-----GQTEPHTVLFHEP 82
R++ L W +A+ + ++G PR+ +K + + V + HT L E
Sbjct: 6 RIVCLFWGVLLTARANYQNGKNNVPRLKLSYKEMLESNNVITFNGLANSSSYHTFLLDEE 65
Query: 83 GSSSVWVGGRGKVYLFDFPEGKN--------------------ASVRTDCENYITLLERR 122
S ++VG + ++ FD K+ + +C N+I +L+
Sbjct: 66 -RSRLYVGAKDHIFSFDLVNIKDFQKIVWPVSYTRRDECKWAGKDILKECANFIKVLKAY 124
Query: 123 SEG-LLACGTNARHPSCWNLVNG-----TVVPLGEM-----RGYAPFSPDENSLVLFEGD 171
++ L ACGT A HP C + G + L RG +P+ P + L
Sbjct: 125 NQTHLYACGTGAFHPICTYIEIGHHPEDNIFKLENSHFENGRGKSPYDPKLLTASLLIDG 184
Query: 172 EVYSTIRKQEYNGKIPRFRRIRGESELYTSD---TVMQNPQFIKATIVHQ-DQAYDDKIY 227
E+YS FR + + T + +P+FI A ++ + D DDK+Y
Sbjct: 185 ELYSGTAADFMGRDFAIFRTLGHHHPIRTEQHDSRWLNDPKFISAHLISESDNPEDDKVY 244
Query: 228 YFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATN---K 284
+FFRE+ D +R+ Q+C+ D GG SL V+KW TFLKA L+CS N
Sbjct: 245 FFFRENAIDGEHSGKATHARIGQICKNDFGGHRSL-VNKWTTFLKARLICSVPGPNGIDT 303
Query: 285 NFNRLQDVFLL--PDPSGQWRDTRVYGVF---SNPWNYSAVCVYSLGDIDKVFR------ 333
+F+ LQDVFL+ DP ++ VYGVF SN + SAVC+YS+ D+ +VF
Sbjct: 304 HFDELQDVFLMNFKDP----KNPVVYGVFTTSSNIFKGSAVCMYSMSDVRRVFLGPYAHR 359
Query: 334 ---TSSLKGYHSSLPNPRPGKC-------LPDQQPIPTETFQVADRHPEVAQRVEPMGP- 382
Y +P PRPG C + +P + A HP + V PM
Sbjct: 360 DGPNYQWVPYQGRVPYPRPGTCPSKTFGGFDSTKDLPDDVITFARSHPAMYNPVFPMNNR 419
Query: 383 ---LKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVE-PGEQEHSFAFN 438
+KT + Y + ++ V R+ A G+ + V+++ TD GT+ KVV P E +
Sbjct: 420 PIVIKTDV---NYQFTQIVVDRVDAEDGQ-YDVMFIGTDVGTVLKVVSIPKETWYDLEEV 475
Query: 439 IME-IQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYC 497
++E + FR AI M L ++++LY+ S V+Q+PL C++YG C C ++RDPYC
Sbjct: 476 LLEEMTVFREPTAISAMELSTKQQQLYIGSTAGVAQLPLHRCDIYGKACAECCLARDPYC 535
Query: 498 GWDQGRCISIY--SSERSVLQSINPAEPHKECPNPKPDK----APLQKVSL-APNSRYYL 550
WD C + + R+ Q I +P C + D +P +++ NS +L
Sbjct: 536 AWDGSACSRYFPTAKRRTRRQDIRNGDPLTHCSDLHHDNHHGHSPEERIIYGVENSSTFL 595
Query: 551 SCPMESRHATYSWRHKENVEQSCEPGHQSPNCI-----LFIENLTAQQYGHYFCEAQEGS 605
C +S+ A W+ + E+ E + I L + +L + G+Y C A E
Sbjct: 596 ECSPKSQRALVYWQFQRRNEERKEEIRVDDHIIRTDQGLLLRSLQQKDSGNYLCHAVEHG 655
Query: 606 YFR 608
+ +
Sbjct: 656 FIQ 658
>gi|54607089 semaphorin 3B isoform 2 precursor [Homo sapiens]
Length = 748
Score = 220 bits (561), Expect = 3e-57
Identities = 173/568 (30%), Positives = 256/568 (45%), Gaps = 55/568 (9%)
Query: 108 VRTDCENYITLLERRSEG-LLACGTNARHPSCWNLVNGTVVP----------LGEMRGYA 156
+ T+C N++ LL + LLACGT A HP+C + G + + +G +
Sbjct: 109 IGTECMNFVKLLHAYNRTHLLACGTGAFHPTCAFVEVGHRAEEPVLRLDPGRIEDGKGKS 168
Query: 157 PFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTS---DTVMQNPQFIKA 213
P+ P + + G+E+YS + FR + L T + P+F+K
Sbjct: 169 PYDPRHRAASVLVGEELYSGVAADLMGRDFTIFRSLGQRPSLRTEPHDSRWLNEPKFVKV 228
Query: 214 T-IVHQDQAYDDKIYYFFREDNPDKNPE-APLNVSRVAQLCRGDQGGESSLSVSKWNTFL 271
I + DDKIY+FFRE + P L+VSRV Q+CR D GG+ SL V+KW TFL
Sbjct: 229 FWIPESENPDDDKIYFFFRETAVEAAPALGRLSVSRVGQICRNDVGGQRSL-VNKWTTFL 287
Query: 272 KAMLVCSDAAT--NKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNP--WNYSAVCVYSLGD 327
KA LVCS + +F++LQDVFLL S R +Y VFS + SAVCVYS+ D
Sbjct: 288 KARLVCSVPGVEGDTHFDQLQDVFLLS--SRDHRTPLLYAVFSTSSIFQGSAVCVYSMND 345
Query: 328 IDKVFR---------TSSLKGYHSSLPNPRPGKC-------LPDQQPIPTETFQVADRHP 371
+ + F Y +P PRPG C + P + Q A HP
Sbjct: 346 VRRAFLGPFAHKEGPMHQWVSYQGRVPYPRPGMCPSKTFGTFSSTKDFPDDVIQFARNHP 405
Query: 372 EVAQRVEPMGPLKTPLF---HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVE- 427
+ V P G PLF + Y + ++A R+ A+ G + VL++ TD GT+ KV+
Sbjct: 406 LMYNSVLPTGG--RPLFLQVGANYTFTQIAADRVAAADGH-YDVLFIGTDVGTVLKVISV 462
Query: 428 -PGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGC 486
G + + + E+ F +AA+ +M + ++R +LYV+S+ V+Q+ L C +G C
Sbjct: 463 PKGSRPSAEGLLLEELHVFEDSAAVTSMQISSKRHQLYVASRSAVAQIALHRCAAHGRVC 522
Query: 487 HGCLMSRDPYCGWDQGRCISIYSS--ERSVLQSINPAEPHKECPNPKPDKAPLQ-KVSLA 543
C ++RDPYC WD C S R Q + +P C A L+ KV
Sbjct: 523 TECCLARDPYCAWDGVACTRFQPSAKRRFRRQDVRNGDPSTLCSGDSSRPALLEHKVFGV 582
Query: 544 PNSRYYLSCPMESRHATYSWRHKE-----NVEQSCEPGHQSPNCILFIENLTAQQYGHYF 598
S +L C S A W + + + E + L + L + G Y
Sbjct: 583 EGSSAFLECEPRSLQARVEWTFQRAGVTAHTQVLAEERTERTARGLLLRRLRRRDSGVYL 642
Query: 599 CEAQEGSYFREAQHWQLLPEDGIMAEHL 626
C A E + + + L AE L
Sbjct: 643 CAAVEQGFTQPLRRLSLHVLSATQAERL 670
>gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens]
Length = 749
Score = 220 bits (560), Expect = 4e-57
Identities = 173/569 (30%), Positives = 256/569 (44%), Gaps = 56/569 (9%)
Query: 108 VRTDCENYITLLERRSEG-LLACGTNARHPSCWNLVNGTVVP----------LGEMRGYA 156
+ T+C N++ LL + LLACGT A HP+C + G + + +G +
Sbjct: 109 IGTECMNFVKLLHAYNRTHLLACGTGAFHPTCAFVEVGHRAEEPVLRLDPGRIEDGKGKS 168
Query: 157 PFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTS---DTVMQNPQFIKA 213
P+ P + + G+E+YS + FR + L T + P+F+K
Sbjct: 169 PYDPRHRAASVLVGEELYSGVAADLMGRDFTIFRSLGQRPSLRTEPHDSRWLNEPKFVKV 228
Query: 214 T-IVHQDQAYDDKIYYFFREDNPDKNPE-APLNVSRVAQLCRGDQGGESSLSVSKWNTFL 271
I + DDKIY+FFRE + P L+VSRV Q+CR D GG+ SL V+KW TFL
Sbjct: 229 FWIPESENPDDDKIYFFFRETAVEAAPALGRLSVSRVGQICRNDVGGQRSL-VNKWTTFL 287
Query: 272 KAMLVCSDAAT--NKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNP---WNYSAVCVYSLG 326
KA LVCS + +F++LQDVFLL S R +Y VFS + SAVCVYS+
Sbjct: 288 KARLVCSVPGVEGDTHFDQLQDVFLLS--SRDHRTPLLYAVFSTSSSIFQGSAVCVYSMN 345
Query: 327 DIDKVFR---------TSSLKGYHSSLPNPRPGKC-------LPDQQPIPTETFQVADRH 370
D+ + F Y +P PRPG C + P + Q A H
Sbjct: 346 DVRRAFLGPFAHKEGPMHQWVSYQGRVPYPRPGMCPSKTFGTFSSTKDFPDDVIQFARNH 405
Query: 371 PEVAQRVEPMGPLKTPLF---HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVE 427
P + V P G PLF + Y + ++A R+ A+ G + VL++ TD GT+ KV+
Sbjct: 406 PLMYNSVLPTGG--RPLFLQVGANYTFTQIAADRVAAADGH-YDVLFIGTDVGTVLKVIS 462
Query: 428 --PGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGG 485
G + + + E+ F +AA+ +M + ++R +LYV+S+ V+Q+ L C +G
Sbjct: 463 VPKGSRPSAEGLLLEELHVFEDSAAVTSMQISSKRHQLYVASRSAVAQIALHRCAAHGRV 522
Query: 486 CHGCLMSRDPYCGWDQGRCISIYSS--ERSVLQSINPAEPHKECPNPKPDKAPLQ-KVSL 542
C C ++RDPYC WD C S R Q + +P C A L+ KV
Sbjct: 523 CTECCLARDPYCAWDGVACTRFQPSAKRRFRRQDVRNGDPSTLCSGDSSRPALLEHKVFG 582
Query: 543 APNSRYYLSCPMESRHATYSWRHKE-----NVEQSCEPGHQSPNCILFIENLTAQQYGHY 597
S +L C S A W + + + E + L + L + G Y
Sbjct: 583 VEGSSAFLECEPRSLQARVEWTFQRAGVTAHTQVLAEERTERTARGLLLRRLRRRDSGVY 642
Query: 598 FCEAQEGSYFREAQHWQLLPEDGIMAEHL 626
C A E + + + L AE L
Sbjct: 643 LCAAVEQGFTQPLRRLSLHVLSATQAERL 671
>gi|5454048 semaphorin 3C [Homo sapiens]
Length = 751
Score = 212 bits (539), Expect = 1e-54
Identities = 166/545 (30%), Positives = 253/545 (46%), Gaps = 56/545 (10%)
Query: 112 CENYITLLERRSEG-LLACGTNARHPSCWNLVNGT-----VVPLGEM----RGYAPFSPD 161
C N++ +++ + L CG+ A P C L G V + +G F+P+
Sbjct: 112 CGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPN 171
Query: 162 ENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYT---SDTVMQNPQFIKATIVHQ 218
N++ + +E++S + FR + + + T + + P F+ A ++
Sbjct: 172 VNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPD 231
Query: 219 DQAYDD-KIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVC 277
+D K+Y+FF+E D N S +A++C D GG SL V+KW TFLKA LVC
Sbjct: 232 GTDPNDAKVYFFFKEKLTDNNRSTKQIHSMIARICPNDTGGLRSL-VNKWTTFLKARLVC 290
Query: 278 S---DAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVF---SNPWNYSAVCVYSLGDIDKV 331
S + +F+ L+DVFLL + R T VYG+F S+ + SAVCVY L DI V
Sbjct: 291 SVTDEDGPETHFDELEDVFLLETDNP--RTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTV 348
Query: 332 FR---------TSSLKGYHSSLPNPRPGKC--------LPDQQPIPTETFQVADRHPEVA 374
F L Y +P PRPG C + + P + HP +
Sbjct: 349 FNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMY 408
Query: 375 QRVEPMGPLKTPLF---HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVE-PGE 430
+ P+ K PL + Y Y K+AV R+ A+ G +HVL+L TDRGT+ KVV P
Sbjct: 409 NSIYPIH--KRPLIVRIGTDYKYTKIAVDRVNAADGR-YHVLFLGTDRGTVQKVVVLPTN 465
Query: 431 QEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCL 490
S + E++ F+ A I TM + +++++LYVSS VSQV L C +YG C C
Sbjct: 466 NSVSGELILEELEVFKNHAPITTMKISSKKQQLYVSSNEGVSQVSLHRCHIYGTACADCC 525
Query: 491 MSRDPYCGWDQGRCISIY--SSERSVLQSINPAEPHKECP--NPKPDKAPLQKVSL-APN 545
++RDPYC WD C Y RS Q + P +C N K + + V N
Sbjct: 526 LARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVKN 585
Query: 546 SRYYLSCPMESRHATYSWRHKENVEQSCEPGHQ----SPNCILFIENLTAQQYGHYFCEA 601
+ +L C +S A+ W +++ ++ E + + L I ++ G Y C A
Sbjct: 586 NTTFLECAPKSPQASIKWLLQKDKDRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIA 645
Query: 602 QEGSY 606
E S+
Sbjct: 646 TENSF 650
>gi|188497703 semaphorin 3F [Homo sapiens]
Length = 785
Score = 197 bits (500), Expect = 3e-50
Identities = 184/718 (25%), Positives = 297/718 (41%), Gaps = 135/718 (18%)
Query: 35 LLLWAAAASA-------QGHLRSGPRIFAVWKGHVGQDRVDFGQ----TEPHTVLFHEPG 83
LLLWA+ + Q HL + PR+ +K F T + +L +
Sbjct: 6 LLLWASLLTGAWPSFPTQDHLPATPRVRLSFKELKATGTAHFFNFLLNTTDYRILLKDED 65
Query: 84 SSSVWVGGRGKVYLFDFPE-----------------------GKNASVRTDCENYITLLE 120
++VG + V D + GK+ V +C N++ L++
Sbjct: 66 HDRMYVGSKDYVLSLDLHDINREPLIIHWAASPQRIEECVLSGKD--VNGECGNFVRLIQ 123
Query: 121 RRSEG-LLACGTNARHPSC-------------WN-----------LVNGTVVP------- 148
+ L CGT A +P C W +G + P
Sbjct: 124 PWNRTHLYVCGTGAYNPMCTYVNRGRRAQATPWTQTQAVRGRGSRATDGALRPMPTAPRQ 183
Query: 149 ----------LGEMRGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESEL 198
L +G P+ P ++ +E+Y+ + FR + ++ +
Sbjct: 184 DYIFYLEPERLESGKGKCPYDPKLDTASALINEELYAGVYIDFMGTDAAIFRTLGKQTAM 243
Query: 199 YT---SDTVMQNPQFIKATIVHQD-QAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRG 254
T + + +P FI A ++ + DDK+Y+FFRE + + P++P +R+ ++C
Sbjct: 244 RTDQYNSRWLNDPSFIHAELIPDSAERNDDKLYFFFRERSAEA-PQSPAVYARIGRICLN 302
Query: 255 DQGGESSLSVSKWNTFLKAMLVCS---DAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVF 311
D GG L V+KW+TFLKA LVCS + +F+ LQDVF+ + R+ +Y VF
Sbjct: 303 DDGGHCCL-VNKWSTFLKARLVCSVPGEDGIETHFDELQDVFV--QQTQDVRNPVIYAVF 359
Query: 312 SNPWNY---SAVCVYSLGDIDKVFR---------TSSLKGYHSSLPNPRPGKC------- 352
++ + SAVCVYS+ DI VF + +P PRPG C
Sbjct: 360 TSSGSVFRGSAVCVYSMADIRMVFNGPFAHKEGPNYQWMPFSGKMPYPRPGTCPGGTFTP 419
Query: 353 -LPDQQPIPTETFQVADRHPEVAQRVEPMGPLKTPLF---HSKYHYQKVAVHRMQASHGE 408
+ + P E HP + Q V P+ + PL + Y +AV ++ A+ G
Sbjct: 420 SMKSTKDYPDEVINFMRSHPLMYQAVYPLQ--RRPLVVRTGAPYRLTTIAVDQVDAADGR 477
Query: 409 TFHVLYLTTDRGTIHKVVE-PGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSS 467
+ VL+L TDRGT+ KV+ P + + + E++ F+ A ++TM++ ++R++LYV+S
Sbjct: 478 -YEVLFLGTDRGTVQKVIVLPKDDQELEELMLEEVEVFKDPAPVKTMTISSKRQQLYVAS 536
Query: 468 QWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQGRC--ISIYSSERSVLQSINPAEPHK 525
V+ + L C+ YG C C ++RDPYC WD C + S RS Q + P +
Sbjct: 537 AVGVTHLSLHRCQAYGAACADCCLARDPYCAWDGQACSRYTASSKRRSRRQDVRHGNPIR 596
Query: 526 ECP--NPKPDKAPLQKVSL-APNSRYYLSCPMESRHATYSWRHKENV-----EQSCEPGH 577
+C N +K ++ V S +L C S AT W + + E E
Sbjct: 597 QCRGFNSNANKNAVESVQYGVAGSAAFLECQPRSPQATVKWLFQRDPGDRRREIRAEDRF 656
Query: 578 QSPNCILFIENLTAQQYGHYFCEAQEGSYFREAQHWQLLPEDGIMAEHLLGHACALAA 635
L + L G Y C A E ++ QL H+LG AA
Sbjct: 657 LRTEQGLLLRALQLSDRGLYSCTATENNFKHVVTRVQL---------HVLGRDAVHAA 705
>gi|214010218 semaphorin 4D isoform 1 [Homo sapiens]
Length = 862
Score = 194 bits (493), Expect = 2e-49
Identities = 167/616 (27%), Positives = 270/616 (43%), Gaps = 94/616 (15%)
Query: 66 RVDFGQTEPHTVLFHEP------------GSSSVWVGGRGKVY--------------LFD 99
R+ + E H V FHEP ++++G R V+ +
Sbjct: 29 RITWEHREVHLVQFHEPDIYNYSALLLSEDKDTLYIGAREAVFAVNALNISEKQHEVYWK 88
Query: 100 FPEGKNA-------SVRTDCENYITLLERRS-EGLLACGTNARHPSCWNLVNGTVVPLG- 150
E K A S +T+C NYI +L+ S L CGTNA P+C +L + LG
Sbjct: 89 VSEDKKAKCAEKGKSKQTECLNYIRVLQPLSATSLYVCGTNAFQPACDHLNLTSFKFLGK 148
Query: 151 --EMRGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTV--MQ 206
+ +G PF P + + E+YS + G P R S L T + +
Sbjct: 149 NEDGKGRCPFDPAHSYTSVMVDGELYSG-TSYNFLGSEPIISRNSSHSPLRTEYAIPWLN 207
Query: 207 NPQFIKATIVHQD----QAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSL 262
P F+ A ++ + DD++Y+FF E + + + + R+A++C+GDQGG +L
Sbjct: 208 EPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSVEYEFVFRVLIPRIARVCKGDQGGLRTL 267
Query: 263 SVSKWNTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFS---NPWNYSA 319
KW +FLKA L+CS + FN L+DVF+L P + Y +F+ N SA
Sbjct: 268 Q-KKWTSFLKARLICSRPDSGLVFNVLRDVFVLRSPG--LKVPVFYALFTPQLNNVGLSA 324
Query: 320 VCVYSLGDIDKVFRTSSLK-------------GYHSSLPNPRPGKCLPDQQ--------- 357
VC Y+L ++VF Y+ +P PRPG C+ +
Sbjct: 325 VCAYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNGPVPKPRPGACIDSEARAANYTSSL 384
Query: 358 PIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTT 417
+P +T Q HP + V P+ + L +Y ++ V R QA G + V++++T
Sbjct: 385 NLPDKTLQFVKDHPLMDDSVTPIDN-RPRLIKKDVNYTQIVVDRTQALDGTVYDVMFVST 443
Query: 418 DRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAER--RKLYVSSQWEVSQVP 475
DRG +HK + H I E Q F+ +QT+ L +++ R +Y S V Q P
Sbjct: 444 DRGALHKAISLEHAVHI----IEETQLFQDFEPVQTLLLSSKKGNRFVYAGSNSGVVQAP 499
Query: 476 LDLCEVYGGGCHGCLMSRDPYCGWD--QGRCISIYSSE---RSVLQSINPAEPHKECPNP 530
L C + G C C+++RDPYC W C++++ +E R ++Q + + CP+
Sbjct: 500 LAFCGKH-GTCEDCVLARDPYCAWSPPTATCVALHQTESPSRGLIQEM--SGDASVCPD- 555
Query: 531 KPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPGH---QSPNCILFIE 587
K ++ L C +S A W+ + V ++ P + N ++F
Sbjct: 556 -KSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPKYGLMGRKNLLIF-- 612
Query: 588 NLTAQQYGHYFCEAQE 603
NL+ G Y C ++E
Sbjct: 613 NLSEGDSGVYQCLSEE 628
>gi|41406086 semaphorin 3D [Homo sapiens]
Length = 777
Score = 194 bits (492), Expect = 3e-49
Identities = 159/574 (27%), Positives = 264/574 (45%), Gaps = 63/574 (10%)
Query: 88 WVGGRGKVYLFDFPEGKNASVRTDCENYITLLERRSEG-LLACGTNARHPSCWNLVNGTV 146
W + +V L GK+A+ T+C N+I +L+ ++ + CGT A HP C + G
Sbjct: 107 WPAAKERVELCKLA-GKDAN--TECANFIRVLQPYNKTHIYVCGTGAFHPICGYIDLGVY 163
Query: 147 VP----------LGEMRGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGES 196
L R PF P + + + +YS ++ GK F R G +
Sbjct: 164 KEDIIFKLDTHNLESGRLKCPFDPQQPFASVMTDEYLYSGTAS-DFLGKDTAFTRSLGPT 222
Query: 197 ELY-------TSDTVMQNPQFIKATIVHQD-QAYDDKIYYFFREDNPDKNPEAPLNVSRV 248
+ + + +FI + DDKIY+FFRE + + + +SRV
Sbjct: 223 HDHHYIRTDISEHYWLNGAKFIGTFFIPDTYNPDDDKIYFFFRESSQEGSTSDKTILSRV 282
Query: 249 AQLCRGDQGGESSLSVSKWNTFLKAMLVCS---DAATNKNFNRLQDVFLLPDPSGQWRDT 305
++C+ D GG+ SL ++KW TFLKA L+CS + F+ LQD++LLP + R+
Sbjct: 283 GRVCKNDVGGQRSL-INKWTTFLKARLICSIPGSDGADTYFDELQDIYLLP--TRDERNP 339
Query: 306 RVYGVF---SNPWNYSAVCVYSLGDIDKVFRTSSLKG---------YHSSLPNPRPGKC- 352
VYGVF S+ + SAVCVYS+ DI VF Y +P PRPG C
Sbjct: 340 VVYGVFTTTSSIFKGSAVCVYSMADIRAVFNGPYAHKESADHRWVQYDGRIPYPRPGTCP 399
Query: 353 -------LPDQQPIPTETFQVADRHPEVAQRVEPMGPLKT-PLFHSKYHYQKVAVHRMQA 404
+ + P + RH + + V P+ T + Y ++ V + A
Sbjct: 400 SKTYDPLIKSTRDFPDDVISFIKRHSVMYKSVYPVAGGPTFKRINVDYRLTQIVVDHVIA 459
Query: 405 SHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIME-IQPFRRAAAIQTMSLDAERRKL 463
G+ + V++L TD GT+ KVV +++ + ++E +Q F+ ++ I M L ++++L
Sbjct: 460 EDGQ-YDVMFLGTDIGTVLKVVSISKEKWNMEEVVLEELQIFKHSSIILNMELSLKQQQL 518
Query: 464 YVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQGRC--ISIYSSERSVLQSINPA 521
Y+ S+ + Q+ L C+ YG C C ++RDPYC WD C + S R+ Q +
Sbjct: 519 YIGSRDGLVQLSLHRCDTYGKACADCCLARDPYCAWDGNACSRYAPTSKRRARRQDVKYG 578
Query: 522 EPHKEC----PNPKPDKAPLQKVSLAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPGH 577
+P +C + + A + + + +L C +S+ AT W + + ++ E
Sbjct: 579 DPITQCWDIEDSISHETADEKVIFGIEFNSTFLECIPKSQQATIKWYIQRSGDEHREELK 638
Query: 578 QSPNCI-----LFIENLTAQQYGHYFCEAQEGSY 606
I L I +L + G Y+C+AQE ++
Sbjct: 639 PDERIIKTEYGLLIRSLQKKDSGMYYCKAQEHTF 672
>gi|6912650 semaphorin 3E [Homo sapiens]
Length = 775
Score = 193 bits (490), Expect = 5e-49
Identities = 177/659 (26%), Positives = 284/659 (43%), Gaps = 99/659 (15%)
Query: 34 LLLLWAAAASAQGHLRSGPRIFAVWKGHVGQDRVD-----FGQTEPHTVLFHEPGSSSVW 88
LL LW +A + PR+ K + +R FG + HT+L E ++
Sbjct: 16 LLELWTGGHTAD---TTHPRLRLSHKELLNLNRTSIFHSPFGFLDLHTMLLDEY-QERLF 71
Query: 89 VGGRGKVYLFDFP-----------------------EGKNASVRTDCENYITLLERRSEG 125
VGGR VY +GK+A +C NY+ +L +
Sbjct: 72 VGGRDLVYSLSLERISDGYKEIHWPSTALKMEECIMKGKDAG---ECANYVRVLHHYNRT 128
Query: 126 -LLACGTNARHPSCWNLVNGTVV--PLGEM--------RGYAPFSPDENSLVLFEGDEVY 174
LL CGT A P C + G + PL + RG PF P + + G E++
Sbjct: 129 HLLTCGTGAFDPVCAFIRVGYHLEDPLFHLESPRSERGRGRCPFDPSSSFISTLIGSELF 188
Query: 175 STIRKQEYNGKIPRFRRIRGESELYTS---DTVMQNPQFIKATIVHQDQAYDD-KIYYFF 230
+ + ++ FR + + + T + +++ P+F+ + ++ ++ DD K+Y+FF
Sbjct: 189 AGLYSDYWSRDAAIFRSMGRLAHIRTEHDDERLLKEPKFVGSYMIPDNEDRDDNKVYFFF 248
Query: 231 REDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATN---KNFN 287
E + A +RV +LC D GG+ L V+KW+TFLKA LVCS N F+
Sbjct: 249 TEKALEAENNAHAIYTRVGRLCVNDVGGQRIL-VNKWSTFLKARLVCSVPGMNGIDTYFD 307
Query: 288 RLQDVFLLPDPSGQWRDTRVYGVF---SNPWNYSAVCVYSLGDIDKVFRT--SSLKG--- 339
L+DVFLLP + ++ ++G+F SN + A+CVY + I F + +G
Sbjct: 308 ELEDVFLLP--TRDHKNPVIFGLFNTTSNIFRGHAICVYHMSSIRAAFNGPYAHKEGPEY 365
Query: 340 ----YHSSLPNPRPGKCLPD--------QQPIPTETFQVADRHPEVAQRVEPMGPLKTPL 387
Y +P PRPG C + P + + A HP + Q ++P K P+
Sbjct: 366 HWSVYEGKVPYPRPGSCASKVNGGRYGTTKDYPDDAIRFARSHPLMYQAIKPAH--KKPI 423
Query: 388 F---HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFNIM--EI 442
KY+ +++AV R++A G+ + VL++ TD G + KV+ QE ++ E+
Sbjct: 424 LVKTDGKYNLKQIAVDRVEAEDGQ-YDVLFIGTDNGIVLKVITIYNQEMESMEEVILEEL 482
Query: 443 QPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWDQG 502
Q F+ I +M + ++R++LY+ S V+QV C++YG C C ++RDPYC WD
Sbjct: 483 QIFKDPVPIISMEISSKRQQLYIGSASAVAQVRFHHCDMYGSACADCCLARDPYCAWDGI 542
Query: 503 RCISIY-----SSERSVLQSINPAEPHKEC-----PNPKPDKAPLQKVSLAPNSRYYLSC 552
C Y + R Q + ++C DK N+ L C
Sbjct: 543 SCSRYYPTGTHAKRRFRRQDVRHGNAAQQCFGQQFVGDALDKTEEHLAYGIENNSTLLEC 602
Query: 553 PMESRHATYSWRHKENVEQSCEPGHQSPNCI-----LFIENLTAQQYGHYFCEAQEGSY 606
S A W ++ E E + L L G YFC+ E S+
Sbjct: 603 TPRSLQAKVIWFVQKGRETRKEEVKTDDRVVKMDLGLLFLRLHKSDAGTYFCQTVEHSF 661
>gi|214010220 semaphorin 4D isoform 2 [Homo sapiens]
Length = 738
Score = 190 bits (482), Expect = 4e-48
Identities = 155/546 (28%), Positives = 243/546 (44%), Gaps = 91/546 (16%)
Query: 66 RVDFGQTEPHTVLFHEP------------GSSSVWVGGRGKVY--------------LFD 99
R+ + E H V FHEP ++++G R V+ +
Sbjct: 29 RITWEHREVHLVQFHEPDIYNYSALLLSEDKDTLYIGAREAVFAVNALNISEKQHEVYWK 88
Query: 100 FPEGKNA-------SVRTDCENYITLLERRS-EGLLACGTNARHPSCWNLVNGTVVPLG- 150
E K A S +T+C NYI +L+ S L CGTNA P+C +L + LG
Sbjct: 89 VSEDKKAKCAEKGKSKQTECLNYIRVLQPLSATSLYVCGTNAFQPACDHLNLTSFKFLGK 148
Query: 151 --EMRGYAPFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTV--MQ 206
+ +G PF P + + E+YS + G P R S L T + +
Sbjct: 149 NEDGKGRCPFDPAHSYTSVMVDGELYSG-TSYNFLGSEPIISRNSSHSPLRTEYAIPWLN 207
Query: 207 NPQFIKATIVHQD----QAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSL 262
P F+ A ++ + DD++Y+FF E + + + + R+A++C+GDQGG +L
Sbjct: 208 EPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSVEYEFVFRVLIPRIARVCKGDQGGLRTL 267
Query: 263 SVSKWNTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFS---NPWNYSA 319
KW +FLKA L+CS + FN L+DVF+L P + Y +F+ N SA
Sbjct: 268 Q-KKWTSFLKARLICSRPDSGLVFNVLRDVFVLRSPG--LKVPVFYALFTPQLNNVGLSA 324
Query: 320 VCVYSLGDIDKVFRTSSLK-------------GYHSSLPNPRPGKCLPDQQ--------- 357
VC Y+L ++VF Y+ +P PRPG C+ +
Sbjct: 325 VCAYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNGPVPKPRPGACIDSEARAANYTSSL 384
Query: 358 PIPTETFQVADRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTT 417
+P +T Q HP + V P+ + L +Y ++ V R QA G + V++++T
Sbjct: 385 NLPDKTLQFVKDHPLMDDSVTPIDN-RPRLIKKDVNYTQIVVDRTQALDGTVYDVMFVST 443
Query: 418 DRGTIHKVVEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAER--RKLYVSSQWEVSQVP 475
DRG +HK + H I E Q F+ +QT+ L +++ R +Y S V Q P
Sbjct: 444 DRGALHKAISLEHAVHI----IEETQLFQDFEPVQTLLLSSKKGNRFVYAGSNSGVVQAP 499
Query: 476 LDLCEVYGGGCHGCLMSRDPYCGWD--QGRCISIYSSE---RSVLQ------SINPAEPH 524
L C + G C C+++RDPYC W C++++ +E R ++Q S+ PA
Sbjct: 500 LAFCGKH-GTCEDCVLARDPYCAWSPPTATCVALHQTESPSRGLIQEMSGDASVCPASSP 558
Query: 525 KECPNP 530
K P P
Sbjct: 559 KPLPPP 564
>gi|9910362 semaphorin sem2 [Homo sapiens]
Length = 782
Score = 183 bits (465), Expect = 4e-46
Identities = 159/546 (29%), Positives = 241/546 (44%), Gaps = 74/546 (13%)
Query: 110 TDCENYITLLERRSEG-LLACGTNARHPSCWNLVNGTVVPLGEM------------RGYA 156
T+C N++ +L+ + LLACGT A P+C + TV GE RG
Sbjct: 114 TECANFVRVLQPHNRTHLLACGTGAFQPTCALI---TVGHRGEHVLHLEPGSVESGRGRC 170
Query: 157 PFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDT---VMQNPQFIKA 213
P P F E+Y+ + ++ G+ R G SD+ ++ +P+F+ A
Sbjct: 171 PHEPSRPFASTFIDGELYTGLTA-DFLGREAMIFRSGGPRPALRSDSDQSLLHDPRFVMA 229
Query: 214 TIVHQDQAYD-DKIYYFFREDNPDKNPEAPLN---VSRVAQLCRGDQGGESSLSVSKWNT 269
+ ++ D DK+Y+FF E P +P+ N VSRV ++C D GG+ L V+KW+T
Sbjct: 230 ARIPENSDQDNDKVYFFFSETVP--SPDGGSNHVTVSRVGRVCVNDAGGQRVL-VNKWST 286
Query: 270 FLKAMLVCS---DAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNP---WNYSAVCVY 323
FLKA LVCS +F++L+DVFLL +G + VY +FS + AVCVY
Sbjct: 287 FLKARLVCSVPGPGGAETHFDQLEDVFLLWPKAG--KSLEVYALFSTVSAVFQGFAVCVY 344
Query: 324 SLGDIDKVFR---------TSSLKGYHSSLPNPRPGKC-----------LPDQQPIPTET 363
+ DI +VF Y +P PRPG C + P E
Sbjct: 345 HMADIWEVFNGPFAHRDGPQHQWGPYGGKVPFPRPGVCPSKMTAQPGRPFGSTKDYPDEV 404
Query: 364 FQVADRHPEVAQRVEPM-GPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTI 422
Q A HP + V P G H ++ V R++A G T+ V++L TD G++
Sbjct: 405 LQFARAHPLMFWPVRPRHGRPVLVKTHLAQQLHQIVVDRVEAEDG-TYDVIFLGTDSGSV 463
Query: 423 HKVV--EPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCE 480
KV+ + G + E+Q F+ I M + +R+ LYV S+ V+Q+ L CE
Sbjct: 464 LKVIALQAGGSAEPEEVVLEELQVFKVPTPITEMEISVKRQMLYVGSRLGVAQLRLHQCE 523
Query: 481 VYGGGCHGCLMSRDPYCGWDQGRCISIYSS---ERSVLQSINPAEPHKECPNPKPDKAPL 537
YG C C ++RDPYC WD C S R Q I P +C ++ +
Sbjct: 524 TYGTACAECCLARDPYCAWDGASCTHYRPSLGKRRFRRQDIRHGNPALQCLGQSQEEEAV 583
Query: 538 QKVSL-----APNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFIENLTAQ 592
V+ ++ +L C +S A W + PG + P+ + E +
Sbjct: 584 GLVAATMVYGTEHNSTFLECLPKSPQAAVRWLLQ-------RPGDEGPDQVKTDERVLHT 636
Query: 593 QYGHYF 598
+ G F
Sbjct: 637 ERGLLF 642
>gi|19923279 semaphorin W [Homo sapiens]
Length = 770
Score = 180 bits (456), Expect = 4e-45
Identities = 190/704 (26%), Positives = 290/704 (41%), Gaps = 92/704 (13%)
Query: 12 SAPRARVPGPPARLGLPLRLRLLLLLWAAAASAQGHL-RSGPRI-FAVWKGHVGQDRVDF 69
SA R R PGP P L LL +L + G + RS PR + + R
Sbjct: 4 SAARPR-PGPGQPTASPFPLLLLAVL---SGPVSGRVPRSVPRTSLPISEADSCLTRFAV 59
Query: 70 GQTEPHTVLFHEPGSSSVWVGGRGKVYLFDFPEG--------------------KNASVR 109
T ++VL +P S +++VG R ++ P K
Sbjct: 60 PHTYNYSVLLVDPASHTLYVGARDTIFALSLPFSGERPRRIDWMVPEAHRQNCRKKGKKE 119
Query: 110 TDCENYITLLE-RRSEGLLACGTNARHPSCWNLVNGT---VVPLGEMRGYAPFSPDENSL 165
+C N++ +L + LL CGT A P C + V L RG PF P + S
Sbjct: 120 DECHNFVQILAIANASHLLTCGTFAFDPKCGVIDVSRFQQVERLESGRGKCPFEPAQRSA 179
Query: 166 VLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYT-SDTV---MQNPQFIKATIVHQ--- 218
+ G +Y+ K Y G P R G +E + +DT+ + P F+ A +
Sbjct: 180 AVMAGGVLYAATVKN-YLGTEPIITRAVGRAEDWIRTDTLPSWLNAPAFVAAVALSPAEW 238
Query: 219 -DQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVC 277
D+ DD+IY+FF E + + + V RVA++C GD GG +L +W TFLKA L+C
Sbjct: 239 GDEDGDDEIYFFFTETSRAFDSYERIKVPRVARVCAGDLGGRKTLQ-QRWTTFLKADLLC 297
Query: 278 SDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPW---NYSAVCVYSLGDIDKVFR- 333
+ + LQDV +L G YG+FS+ W SAVC + DI V
Sbjct: 298 PGPEHGRASSVLQDVAVLRPELGAGTPI-FYGIFSSQWEGATISAVCAFRPQDIRTVLNG 356
Query: 334 ---------TSSLKGYHSSLPNPRPGKCLPDQQ---------PIPTETFQVADRHPEVAQ 375
L + +P PRPG+C+ + +P HP + +
Sbjct: 357 PFRELKHDCNRGLPVVDNDVPQPRPGECITNNMKLRHFGSSLSLPDRVLTFIRDHPLMDR 416
Query: 376 RVEPMG--PLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEH 433
V P PL L + Y +V HR+ + G+ + VLYL T+ G +H+ V G Q
Sbjct: 417 PVFPADGHPL---LVTTDTAYLRVVAHRVTSLSGKEYDVLYLGTEDGHLHRAVRIGAQ-- 471
Query: 434 SFAFNIME-IQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMS 492
+++E + F ++ M L L V S+ EV+QV C C C+++
Sbjct: 472 ---LSVLEDLALFPEPQPVENMKL--YHSWLLVGSRTEVTQVNTTNCGRL-QSCSECILA 525
Query: 493 RDPYCGWD--QGRCISIYSSERSVLQSINPAEPHKECPNPKPDKAPLQKVSLAPNSRYYL 550
+DP C W C++ R ++Q I A+ CP ++ + +V +A + L
Sbjct: 526 QDPVCAWSFRLDECVAHAGEHRGLVQDIESADVSSLCPKEPGERPVVFEVPVATAAHVVL 585
Query: 551 SCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFIENLTAQQYGHYFCEAQEGSYFREA 610
C S A+ W H+ + + P + +T G Y CE QEG
Sbjct: 586 PCSPSSAWASCVW-HQPSGVTALTPRRDGLEVV-----VTPGAMGAYACECQEGGAAHVV 639
Query: 611 QHWQLL---PEDGIMAEHLLGHACALAASLWLGVL-PTLTLGLL 650
+ L+ D H +G A A +LG+L +LTL L+
Sbjct: 640 AAYSLVWGSQRDAPSRAHTVG---AGLAGFFLGILAASLTLILI 680
>gi|28872814 semaphorin 4G [Homo sapiens]
Length = 843
Score = 170 bits (431), Expect = 3e-42
Identities = 161/606 (26%), Positives = 252/606 (41%), Gaps = 87/606 (14%)
Query: 70 GQTEPHTVLFHEPGSSSVWVGGRGKVYLF---DFPEGKNASV------------------ 108
GQ + ++ L E S+ + VG RG ++ D +G + +
Sbjct: 51 GQAQNYSTLLLEEASARLLVGARGALFSLSANDIGDGAHKEIHWEASPEMQSKCHQKGKN 110
Query: 109 -RTDCENYITLLER-RSEGLLACGTNARHPSCWNL-VNGTVVPLG--EMRGYAPFSPDEN 163
+T+C N++ L+R S L ACGT+A P C + +P E + P+ P
Sbjct: 111 NQTECFNHVRFLQRLNSTHLYACGTHAFQPLCAAIDAEAFTLPTSFEEGKEKCPYDPARG 170
Query: 164 SLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQ---NPQFIKATIVHQDQ 220
L +Y+ R + + IP RR R L T +T M + +F+ + +V + +
Sbjct: 171 FTGLIIDGGLYTATRYEFRS--IPDIRRSRHPHSLRTEETPMHWLNDAEFVFSVLVRESK 228
Query: 221 AY----DDKIYYFFREDNPDKNP------EAPLNVSRVAQLCRGDQGGESSLSVSKWNTF 270
A DDK+YYFF E ++ + V+RVA++C+GD GG+ L KW +F
Sbjct: 229 ASAVGDDDKVYYFFTERATEEGSGSFTQSRSSHRVARVARVCKGDLGGKKILQ-KKWTSF 287
Query: 271 LKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVF--SNPWNY---SAVCVYSL 325
LKA L+C + L+ V L + T Y F S W SA+C Y L
Sbjct: 288 LKARLICHIPL----YETLRGVCSLDAETSS--RTHFYAAFTLSTQWKTLEASAICRYDL 341
Query: 326 GDIDKVFRTSSLK---------GYHSSLPNPRPGKCLPDQ---------QPIPTETFQVA 367
+I VF ++ Y +P PRPG C+ D Q +P+
Sbjct: 342 AEIQAVFAGPYMEYQDGSRRWGRYEGGVPEPRPGSCITDSLRSQGYNSSQDLPSLVLDFV 401
Query: 368 DRHPEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVE 427
HP +A+ V P + L Y + + G T+ +L+L T G IHK V
Sbjct: 402 KLHPLMARPVVPTRG-RPLLLKRNIRYTHLTGTPVTTPAGPTYDLLFLGTADGWIHKAVV 460
Query: 428 PGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCH 487
G H I E Q FR + +++ + + + LYV + V Q+PL C Y C+
Sbjct: 461 LGSGMHI----IEETQVFRESQSVENLVISLLQHSLYVGAPSGVIQLPLSSCSRYRS-CY 515
Query: 488 GCLMSRDPYCGWDQG--RCISI-------YSSERSVLQSINPAEPHKECPNPKPDKAPLQ 538
C+++RDPYCGWD G C + S +++Q I E PL+
Sbjct: 516 DCILARDPYCGWDPGTHACAAATTIANRSQGSRTALIQDIERGNRGCESSRDTGPPPPLK 575
Query: 539 KVSLAPNSRYYLSCPMESRHATYSWRHKENVEQS-CEPGHQSPNCILFIENLTAQQYGHY 597
S+ L C S A W ++ S + G++ L + + + G+Y
Sbjct: 576 TRSVLRGDDVLLPCDQPSNLARALWLLNGSMGLSDGQGGYRVGVDGLLVTDAQPEHSGNY 635
Query: 598 FCEAQE 603
C A+E
Sbjct: 636 GCYAEE 641
>gi|157388902 semaphorin 4C [Homo sapiens]
Length = 833
Score = 167 bits (424), Expect = 2e-41
Identities = 150/546 (27%), Positives = 240/546 (43%), Gaps = 60/546 (10%)
Query: 102 EGKNASVRTDCENYITLLER-RSEGLLACGTNARHPSCWNLVNGTVVPL--GEM---RGY 155
+GKN +T+C N+I L+ + L CGT A P C VN L GE +G
Sbjct: 102 KGKNN--QTECFNFIRFLQPYNASHLYVCGTYAFQPKC-TYVNMLTFTLEHGEFEDGKGK 158
Query: 156 APFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTV---MQNPQFIK 212
P+ P + L E+YS + G P R G ++ + + P F+
Sbjct: 159 CPYDPAKGHAGLLVDGELYSATLNN-FLGTEPIILRNMGPHHSMKTEYLAFWLNEPHFVG 217
Query: 213 ATIVHQDQAY----DDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWN 268
+ V + DDK+Y+FFRE + + A V+RVA++C+GD GG +L KW
Sbjct: 218 SAYVPESVGSFTGDDDKVYFFFRERAVESDCYAEQVVARVARVCKGDMGGARTLQ-RKWT 276
Query: 269 TFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWN---YSAVCVYSL 325
TFLKA L CS FN+LQ + L D S W +T +GVF W SA+C Y L
Sbjct: 277 TFLKARLACSAPNWQLYFNQLQAMHTLQDTS--WHNTTFFGVFQAQWGDMYLSAICEYQL 334
Query: 326 GDIDKVFRTSSLKGYHSS----------LPNPRPGKCL---------PDQQPIPTETFQV 366
+I +VF K YH +P+PRPG C+ +P
Sbjct: 335 EEIQRVFE-GPYKEYHEEAQKWDRYTDPVPSPRPGSCINNWHRRHGYTSSLELPDNILNF 393
Query: 367 ADRHPEVAQRVEPMGPLKTPLFHSK-YHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKV 425
+HP + ++V P PL K ++ + R+ G T+ VL++ T G + K
Sbjct: 394 VKKHPLMEEQVGPR--WSRPLLVKKGTNFTHLVADRVTGLDGATYTVLFIGTGDGWLLKA 451
Query: 426 VEPGEQEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGG 485
V G H I E+Q F + ++++ L ++ L+ S+ ++ Q+P+ C Y
Sbjct: 452 VSLGPWVHL----IEELQLFDQ-EPMRSLVLSQSKKLLFAGSRSQLVQLPVADCMKY-RS 505
Query: 486 CHGCLMSRDPYCGW--DQGRCISIYSSERSVL-QSINPAEPHKEC--PNPKPDKAPLQKV 540
C C+++RDPYC W + RC+++ S+L Q + ++ C K + + +
Sbjct: 506 CADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQHVMTSDTSGICNLRGSKKVRPTPKNI 565
Query: 541 SLAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPG---HQSPNCILFIENLTAQQYGHY 597
++ + L C + S A W + +PG + + L + + G Y
Sbjct: 566 TVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQPGSFLYDARLQALVVMAAQPRHAGAY 625
Query: 598 FCEAQE 603
C ++E
Sbjct: 626 HCFSEE 631
>gi|21361914 semaphorin B [Homo sapiens]
Length = 761
Score = 166 bits (420), Expect = 6e-41
Identities = 173/607 (28%), Positives = 259/607 (42%), Gaps = 87/607 (14%)
Query: 104 KNASVRTDCENYI-TLLERRSEGLLACGTNARHPSCW--NLVNGTVVPLGEMR-----GY 155
K S T C N+I L+ L CGT A P+C L + ++P+ E + G
Sbjct: 116 KKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQ 175
Query: 156 APFSP-DENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKAT 214
+PF P +++ VL +G T+ + G P R G S V++ F++
Sbjct: 176 SPFDPAHKHTAVLVDGMLYSGTMNN--FLGSEPILMRTLG------SQPVLKTDNFLRW- 226
Query: 215 IVHQDQAY------DDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWN 268
+H D ++ +Y+FF E + + L+ SRVA++C+ D GGE L KW
Sbjct: 227 -LHHDASFVAAIPSTQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGEKLLQ-KKWT 284
Query: 269 TFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY-----SAVCVY 323
TFLKA L+C+ FN ++ LLP S +Y VF++ W SAVC +
Sbjct: 285 TFLKAQLLCTQPG-QLPFNVIRHAVLLPADSP--TAPHIYAVFTSQWQVGGTRSSAVCAF 341
Query: 324 SLGDIDKVFR---------TSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVA 374
SL DI++VF+ TS Y NPRPG C P + H +
Sbjct: 342 SLLDIERVFKGKYKELNKETSRWTTYRGPETNPRPGSC--SVGPSSDKALTFMKDHFLMD 399
Query: 375 QRVEPMGPLKTPLF-HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEH 433
++V + TPL S Y ++AV Q G + V+YL T G++HK V G+
Sbjct: 400 EQV-----VGTPLLVKSGVEYTRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGD--- 451
Query: 434 SFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSR 493
S A + EIQ F ++ + L + ++V V +VP C VY C C+++R
Sbjct: 452 SSAHLVEEIQLFPDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVY-ESCVDCVLAR 510
Query: 494 DPYCGWD---QGRCISIYSSERSVLQSINPAEPHKECPNP------KPDKAP--LQKVSL 542
DP+C WD + C+ + S Q + P C + +P P +++V
Sbjct: 511 DPHCAWDPESRTCCLLSAPNLNSWKQDMERGNPEWACASGPMSRSLRPQSRPQIIKEVLA 570
Query: 543 APNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFIENLTAQQYGHYFCEAQ 602
PNS L CP S A+Y W H + + +L +++ G Y C A
Sbjct: 571 VPNSILELPCPHLSALASYYWSHGPAAVPEASSTVYNGSLLLIVQDGVG---GLYQCWAT 627
Query: 603 EG-------SYFREAQHWQLL--PE-DGIMAEHLL--------GHACALAASLWLGVLPT 644
E SY+ ++Q L PE GI EH+ G A A S W +
Sbjct: 628 ENGFSYPVISYWVDSQDQTLALDPELAGIPREHVKVPLTRVSGGAALAAQQSYWPHFVTV 687
Query: 645 LTLGLLV 651
L LV
Sbjct: 688 TVLFALV 694
>gi|11991660 sema domain, transmembrane domain (TM), and cytoplasmic
domain, (semaphorin) 6A [Homo sapiens]
Length = 1030
Score = 145 bits (367), Expect = 9e-35
Identities = 136/446 (30%), Positives = 195/446 (43%), Gaps = 51/446 (11%)
Query: 109 RTDCENYI-TLLERRSEGLLACGTNARHPSCWNLVNGTVVPLG-EMRGYA--PFSPDENS 164
+ +C N+I LL++ + L CGTNA +PSC N T+ P G E G A P+ +
Sbjct: 114 KDECHNFIKVLLKKNDDALFVCGTNAFNPSCRNYKMDTLEPFGDEFSGMARCPYDAKHAN 173
Query: 165 LVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQDQAYDD 224
+ LF ++YS +R + GES T TV + +++K Q Y D
Sbjct: 174 VALFADGKLYSATVTDFLAIDAVIYRSL-GESP--TLRTVKHDSKWLKEPYFVQAVDYGD 230
Query: 225 KIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCS-DAATN 283
IY+FFRE + N + RVAQ+C+ D GG + +W +FLKA L CS ++
Sbjct: 231 YIYFFFREIAVEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSH 290
Query: 284 KNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF--RTSSLK 338
FN LQ V + +G RD V FS P+N SAVC Y + DI VF R K
Sbjct: 291 FYFNILQAVTDVIRING--RDV-VLATFSTPYNSIPGSAVCAYDMLDIASVFTGRFKEQK 347
Query: 339 GYHSS--------LPNPRPGKC--------LPDQQPIPTETFQVADRHPEVAQRVEPMGP 382
S+ +P PRPG C P +T HP + + V +
Sbjct: 348 SPDSTWTPVPDERVPKPRPGCCAGSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSI-- 405
Query: 383 LKTPLF---HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHK----VVEPGEQEHSF 435
P F +Y K+AV + + V++L +++G I K + G S
Sbjct: 406 FNRPWFLRTMVRYRLTKIAVDTAAGPY-QNHTVVFLGSEKGIILKFLARIGNSGFLNDSL 464
Query: 436 AFNIMEIQPFRRAA-------AIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHG 488
M + + + I M LD LYV+ V +VPL CE +G
Sbjct: 465 FLEEMSVYNSEKCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKT 524
Query: 489 CLMSRDPYCGW--DQGRCISIYSSER 512
C+ SRDPYCGW + G C + + R
Sbjct: 525 CIASRDPYCGWIKEGGACSHLSPNSR 550
>gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens]
Length = 1011
Score = 133 bits (335), Expect = 4e-31
Identities = 124/438 (28%), Positives = 192/438 (43%), Gaps = 53/438 (12%)
Query: 109 RTDCENYITL-LERRSEGLLACGTNARHPSCWNLVNGTVVPLGE-MRGYA--PFSPDENS 164
+ +C N+I + + R E + CGTNA +P C T+ GE + G A PF + +
Sbjct: 115 KDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTN 174
Query: 165 LVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQDQAYDD 224
+ LF ++YS +R + S L T + + ++IK Y +
Sbjct: 175 VALFADGKLYSATVADFLASDAVIYRSMGDGSALRT---IKYDSKWIKEPHFLHAIEYGN 231
Query: 225 KIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATN- 283
+Y+FFRE + N SRVA++C+ D GG + W +FLKA L CS +
Sbjct: 232 YVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSF 291
Query: 284 KNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF--RTSSLK 338
F+ LQ + + +G V GVF+ N SAVC +S+ DI+KVF R K
Sbjct: 292 FYFDVLQSITDIIQING---IPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQK 348
Query: 339 GYHS--------SLPNPRPGKC--------LPDQQPIPTETFQVADRHPEVAQRVEPMGP 382
S +P PRPG C P ET HP + V P+
Sbjct: 349 TPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIA- 407
Query: 383 LKTPLF-HSKYHYQKVAVH-RMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFN-- 438
P F ++ Y+ A+ A + + V+++ ++ G + KV+ + F+ N
Sbjct: 408 -DEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVL---AKTSPFSLNDS 463
Query: 439 --IMEIQPFRRAAA---------IQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCH 487
+ EI+ + A + ++ LD + LYV+ + ++PL CE YG
Sbjct: 464 VLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKK 523
Query: 488 GCLMSRDPYCGW-DQGRC 504
C+ SRDPYCGW QG C
Sbjct: 524 SCIASRDPYCGWLSQGSC 541
>gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens]
Length = 597
Score = 133 bits (335), Expect = 4e-31
Identities = 124/438 (28%), Positives = 192/438 (43%), Gaps = 53/438 (12%)
Query: 109 RTDCENYITL-LERRSEGLLACGTNARHPSCWNLVNGTVVPLGE-MRGYA--PFSPDENS 164
+ +C N+I + + R E + CGTNA +P C T+ GE + G A PF + +
Sbjct: 115 KDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTN 174
Query: 165 LVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQDQAYDD 224
+ LF ++YS +R + S L T + + ++IK Y +
Sbjct: 175 VALFADGKLYSATVADFLASDAVIYRSMGDGSALRT---IKYDSKWIKEPHFLHAIEYGN 231
Query: 225 KIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATN- 283
+Y+FFRE + N SRVA++C+ D GG + W +FLKA L CS +
Sbjct: 232 YVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSF 291
Query: 284 KNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF--RTSSLK 338
F+ LQ + + +G V GVF+ N SAVC +S+ DI+KVF R K
Sbjct: 292 FYFDVLQSITDIIQING---IPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQK 348
Query: 339 GYHS--------SLPNPRPGKC--------LPDQQPIPTETFQVADRHPEVAQRVEPMGP 382
S +P PRPG C P ET HP + V P+
Sbjct: 349 TPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIA- 407
Query: 383 LKTPLF-HSKYHYQKVAVH-RMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFN-- 438
P F ++ Y+ A+ A + + V+++ ++ G + KV+ + F+ N
Sbjct: 408 -DEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVL---AKTSPFSLNDS 463
Query: 439 --IMEIQPFRRAAA---------IQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCH 487
+ EI+ + A + ++ LD + LYV+ + ++PL CE YG
Sbjct: 464 VLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKK 523
Query: 488 GCLMSRDPYCGW-DQGRC 504
C+ SRDPYCGW QG C
Sbjct: 524 SCIASRDPYCGWLSQGSC 541
>gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]
Length = 1073
Score = 133 bits (335), Expect = 4e-31
Identities = 124/438 (28%), Positives = 192/438 (43%), Gaps = 53/438 (12%)
Query: 109 RTDCENYITL-LERRSEGLLACGTNARHPSCWNLVNGTVVPLGE-MRGYA--PFSPDENS 164
+ +C N+I + + R E + CGTNA +P C T+ GE + G A PF + +
Sbjct: 115 KDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTN 174
Query: 165 LVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQDQAYDD 224
+ LF ++YS +R + S L T + + ++IK Y +
Sbjct: 175 VALFADGKLYSATVADFLASDAVIYRSMGDGSALRT---IKYDSKWIKEPHFLHAIEYGN 231
Query: 225 KIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATN- 283
+Y+FFRE + N SRVA++C+ D GG + W +FLKA L CS +
Sbjct: 232 YVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSF 291
Query: 284 KNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF--RTSSLK 338
F+ LQ + + +G V GVF+ N SAVC +S+ DI+KVF R K
Sbjct: 292 FYFDVLQSITDIIQING---IPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQK 348
Query: 339 GYHS--------SLPNPRPGKC--------LPDQQPIPTETFQVADRHPEVAQRVEPMGP 382
S +P PRPG C P ET HP + V P+
Sbjct: 349 TPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIA- 407
Query: 383 LKTPLF-HSKYHYQKVAVH-RMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFN-- 438
P F ++ Y+ A+ A + + V+++ ++ G + KV+ + F+ N
Sbjct: 408 -DEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVL---AKTSPFSLNDS 463
Query: 439 --IMEIQPFRRAAA---------IQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCH 487
+ EI+ + A + ++ LD + LYV+ + ++PL CE YG
Sbjct: 464 VLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKK 523
Query: 488 GCLMSRDPYCGW-DQGRC 504
C+ SRDPYCGW QG C
Sbjct: 524 SCIASRDPYCGWLSQGSC 541
>gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]
Length = 1017
Score = 133 bits (335), Expect = 4e-31
Identities = 124/438 (28%), Positives = 192/438 (43%), Gaps = 53/438 (12%)
Query: 109 RTDCENYITL-LERRSEGLLACGTNARHPSCWNLVNGTVVPLGE-MRGYA--PFSPDENS 164
+ +C N+I + + R E + CGTNA +P C T+ GE + G A PF + +
Sbjct: 115 KDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTN 174
Query: 165 LVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQDQAYDD 224
+ LF ++YS +R + S L T + + ++IK Y +
Sbjct: 175 VALFADGKLYSATVADFLASDAVIYRSMGDGSALRT---IKYDSKWIKEPHFLHAIEYGN 231
Query: 225 KIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATN- 283
+Y+FFRE + N SRVA++C+ D GG + W +FLKA L CS +
Sbjct: 232 YVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSF 291
Query: 284 KNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF--RTSSLK 338
F+ LQ + + +G V GVF+ N SAVC +S+ DI+KVF R K
Sbjct: 292 FYFDVLQSITDIIQING---IPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQK 348
Query: 339 GYHS--------SLPNPRPGKC--------LPDQQPIPTETFQVADRHPEVAQRVEPMGP 382
S +P PRPG C P ET HP + V P+
Sbjct: 349 TPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIA- 407
Query: 383 LKTPLF-HSKYHYQKVAVH-RMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFN-- 438
P F ++ Y+ A+ A + + V+++ ++ G + KV+ + F+ N
Sbjct: 408 -DEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVL---AKTSPFSLNDS 463
Query: 439 --IMEIQPFRRAAA---------IQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCH 487
+ EI+ + A + ++ LD + LYV+ + ++PL CE YG
Sbjct: 464 VLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKK 523
Query: 488 GCLMSRDPYCGW-DQGRC 504
C+ SRDPYCGW QG C
Sbjct: 524 SCIASRDPYCGWLSQGSC 541
>gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens]
Length = 998
Score = 133 bits (335), Expect = 4e-31
Identities = 124/438 (28%), Positives = 192/438 (43%), Gaps = 53/438 (12%)
Query: 109 RTDCENYITL-LERRSEGLLACGTNARHPSCWNLVNGTVVPLGE-MRGYA--PFSPDENS 164
+ +C N+I + + R E + CGTNA +P C T+ GE + G A PF + +
Sbjct: 115 KDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTN 174
Query: 165 LVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQDQAYDD 224
+ LF ++YS +R + S L T + + ++IK Y +
Sbjct: 175 VALFADGKLYSATVADFLASDAVIYRSMGDGSALRT---IKYDSKWIKEPHFLHAIEYGN 231
Query: 225 KIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATN- 283
+Y+FFRE + N SRVA++C+ D GG + W +FLKA L CS +
Sbjct: 232 YVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSF 291
Query: 284 KNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF--RTSSLK 338
F+ LQ + + +G V GVF+ N SAVC +S+ DI+KVF R K
Sbjct: 292 FYFDVLQSITDIIQING---IPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQK 348
Query: 339 GYHS--------SLPNPRPGKC--------LPDQQPIPTETFQVADRHPEVAQRVEPMGP 382
S +P PRPG C P ET HP + V P+
Sbjct: 349 TPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIA- 407
Query: 383 LKTPLF-HSKYHYQKVAVH-RMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFN-- 438
P F ++ Y+ A+ A + + V+++ ++ G + KV+ + F+ N
Sbjct: 408 -DEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVL---AKTSPFSLNDS 463
Query: 439 --IMEIQPFRRAAA---------IQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCH 487
+ EI+ + A + ++ LD + LYV+ + ++PL CE YG
Sbjct: 464 VLLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKK 523
Query: 488 GCLMSRDPYCGW-DQGRC 504
C+ SRDPYCGW QG C
Sbjct: 524 SCIASRDPYCGWLSQGSC 541
>gi|147904700 semaphorin 5A [Homo sapiens]
Length = 1074
Score = 132 bits (332), Expect = 1e-30
Identities = 142/494 (28%), Positives = 217/494 (43%), Gaps = 74/494 (14%)
Query: 64 QDRVDFGQTEPHTVLFHEPGSSSVWVGGRGKVYLFD----------------------FP 101
++ VDF Q L +PG + VG R ++ +
Sbjct: 53 KNAVDFSQ------LTFDPGQKELVVGARNYLFRLQLEDLSLIQAVEWECDEATKKACYS 106
Query: 102 EGKNASVRTDCENYITLLERRSEGLLACGTNARHPSCWN--LVNGTVVPLGEMRGYA--P 157
+GK+ + +C+NYI +L + L CGTNA P C N L N T + ++ G A P
Sbjct: 107 KGKS---KEECQNYIRVLLVGGDRLFTCGTNAFTPVCTNRSLSNLTEIH-DQISGMARCP 162
Query: 158 FSPDENSLVLF-EGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIV 216
+SP NS L G E+Y+ ++ G+ P R G L T N +++
Sbjct: 163 YSPQHNSTALLTAGGELYAA-TAMDFPGRDPAIYRSLG--ILPPLRTAQYNSKWLNEPNF 219
Query: 217 HQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLV 276
+ Y+FFRE N ++ SR A++C+ D GG L W TF+KA L
Sbjct: 220 VSSYDIGNFTYFFFRE-NAVEHDCGKTVFSRAARVCKNDIGGRFLLE-DTWTTFMKARLN 277
Query: 277 CS-DAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWN---YSAVCVYSLGDIDKVF 332
CS +N LQ F LP+ +YG+F+ N SAVCV++L I + F
Sbjct: 278 CSRPGEVPFYYNELQSTFFLPELD------LIYGIFTTNVNSIAASAVCVFNLSAIAQAF 331
Query: 333 RTSSLKGYHSS------LPNPRPG-KCLPDQQPIPTETFQVADRHPEVAQRV----EPMG 381
+ K +S PNP P +C Q + + +R+ + AQ+ E +
Sbjct: 332 -SGPFKYQENSRSAWLPYPNPNPHFQCGTVDQGL---YVNLTERNLQDAQKFILMHEVVQ 387
Query: 382 PLKT-PLF-HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEP-GEQEHSFAFN 438
P+ T P F + VAV +Q H++YL TD GTI KV P + S
Sbjct: 388 PVTTVPSFMEDNSRFSHVAVDVVQGREA-LVHIIYLATDYGTIKKVRVPLNQTSSSCLLE 446
Query: 439 IMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCG 498
+E+ P RR I+++ + + L+V + V ++PL C+ Y C+ ++DPYCG
Sbjct: 447 EIELFPERRREPIRSLQILHSQSVLFVGLREHVVKIPLKRCQFYRTR-STCIGAQDPYCG 505
Query: 499 WD--QGRCISIYSS 510
WD +C S+ S
Sbjct: 506 WDVVMKKCTSLEES 519
>gi|16306552 semaphorin Y [Homo sapiens]
Length = 930
Score = 131 bits (330), Expect = 2e-30
Identities = 125/453 (27%), Positives = 195/453 (43%), Gaps = 56/453 (12%)
Query: 104 KNASVR----TDCENYI-TLLERRSEGLLACGTNARHPSCWNLVNGTVVPLGE-MRGYA- 156
+N +VR +C NYI L+ S+ LLACGTN+ P C + ++ GE + G A
Sbjct: 109 ENCAVRGKLTDECYNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQQEGEELSGQAR 168
Query: 157 -PFSPDENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTS---DTVMQNPQFIK 212
PF ++++ +F +YS +R + + L ++ ++ P F++
Sbjct: 169 CPFDATQSNVAIFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVQ 228
Query: 213 ATIVHQDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLK 272
A + D +Y+FFRE + + + SRVA++C+ D GG W +FLK
Sbjct: 229 AL------EHGDHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLK 282
Query: 273 AMLVCSDAATNK-NFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDI 328
L CS + F+ LQ L P + ++GVF+ N SAVC + L +I
Sbjct: 283 LRLNCSVPGDSTFYFDVLQ---ALTGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDEI 339
Query: 329 DKVFRTS-----SLKGY-----HSSLPNPRPGKC--------LPDQQPIPTETFQVADRH 370
++ F SL G +P+PRPG C + +P + H
Sbjct: 340 ERGFEGKFKEQRSLDGAWTPVSEDRVPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAH 399
Query: 371 PEVAQRVEPMGPLKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGE 430
P + V P+ S+ +VAV M H V++L ++ GT+ KV+ PG
Sbjct: 400 PLLDPAVPPVTHQPLLTLTSRALLTQVAVDGMAGPHSN-ITVMFLGSNDGTVLKVLTPGG 458
Query: 431 Q----EHSFAFNIMEIQPFR--------RAAAIQTMSLDAERRKLYVSSQWEVSQVPLDL 478
+ E I P R A I + LD E +L+V+ + +PL
Sbjct: 459 RSGGPEPILLEEIDAYSPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSR 518
Query: 479 CEVYGGGCHGCLMSRDPYCGWDQGR-CISIYSS 510
C +G CL S+DPYCGW R C+ I S
Sbjct: 519 CARHGACQRSCLASQDPYCGWHSSRGCVDIRGS 551
>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
Length = 1151
Score = 130 bits (328), Expect = 3e-30
Identities = 121/436 (27%), Positives = 193/436 (44%), Gaps = 46/436 (10%)
Query: 111 DCENYITLLERRSEGLLACGTNARHPSCWNLVNGTVV-PLGEMRGYA--PFSPDENSLVL 167
+C+NY+ +L + CGTNA P C + G + + ++ G A P+ P NS +
Sbjct: 181 ECQNYVRVLIVAGRKVFMCGTNAFSPMCTSRQVGNLSRTIEKINGVARCPYDPRHNSTAV 240
Query: 168 FEGDEVYSTIRKQEYNGKIPRFRRIRGE-----SELYTSDTVMQNPQFIKATIVHQDQAY 222
+++G+ P R G + Y S + P F+ A Y
Sbjct: 241 ISSQGELYAATVIDFSGRDPAIYRSLGSGPPLRTAQYNSKW-LNEPNFVAA--------Y 291
Query: 223 DDKIY-YFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCS-DA 280
D ++ YFF +N ++ SRVA++C+ D GG L W TF+KA L CS
Sbjct: 292 DIGLFAYFFLRENAVEHDCGRTVYSRVARVCKNDVGGRFLLE-DTWTTFMKARLNCSRPG 350
Query: 281 ATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVFR---- 333
+N LQ F LP+ +YGVF+ N SAVC ++L I + F
Sbjct: 351 EVPFYYNELQSAFHLPEQD------LIYGVFTTNVNSIAASAVCAFNLSAISQAFNGPFR 404
Query: 334 -TSSLKGYHSSLPNPRPG-KC--LPDQQP---IPTETFQVADRHPEVAQRVEPMGPLKTP 386
+ + + NP P +C LP+ P + + Q A R +++ V+P+ P +
Sbjct: 405 YQENPRAAWLPIANPIPNFQCGTLPETGPNENLTERSLQDAQRLFLMSEAVQPVTP-EPC 463
Query: 387 LFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQE-HSFAFNIMEIQPF 445
+ + + V +QA +HVLY+ T+ GTI K + + H + + P
Sbjct: 464 VTQDSVRFSHLVVDLVQAKD-TLYHVLYIGTESGTILKALSTASRSLHGCYLEELHVLPP 522
Query: 446 RRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCGWD--QGR 503
R ++++ + R L+V + V +VPL+ C Y CL +RDPYCGWD Q R
Sbjct: 523 GRREPLRSLRILHSARALFVGLRDGVLRVPLERCAAYRSQ-GACLGARDPYCGWDGKQQR 581
Query: 504 CISIYSSERSVLQSIN 519
C ++ S L + N
Sbjct: 582 CSTLEDSSNMSLWTQN 597
>gi|19718780 semaphorin 6B precursor [Homo sapiens]
Length = 888
Score = 122 bits (305), Expect = 1e-27
Identities = 127/459 (27%), Positives = 198/459 (43%), Gaps = 72/459 (15%)
Query: 111 DCENYITLLERRSEG-LLACGTNARHPSCWNLVNGTVVPLGE-MRGYA--PFSPDENSLV 166
+C N++ +L R E L CG+NA +P C N T+ P+G+ + G A P+ P ++
Sbjct: 125 ECRNFVKVLLLRDESTLFVCGSNAFNPVCANYSIDTLQPVGDNISGMARCPYDPKHANVA 184
Query: 167 LFEGDEVYST-------IRKQEYN--GKIPRFRRIRGESELYTSDTVMQNPQFIKATIVH 217
LF +++ I Y G P R ++ +S+ + + P F+ A
Sbjct: 185 LFSDGMLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWF------KEPYFVHAV--- 235
Query: 218 QDQAYDDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVC 277
+ +Y+FFRE + N + VSRVA++C+ D GG + +W +FLKA L C
Sbjct: 236 ---EWGSHVYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNC 292
Query: 278 S-DAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF- 332
S ++ FN LQ V + G+ V VFS P N SAVC + L + VF
Sbjct: 293 SVPGDSHFYFNVLQAVTGVVSLGGR---PVVLAVFSTPSNSIPGSAVCAFDLTQVAAVFE 349
Query: 333 -RTSSLKGYHS--------SLPNPRPGKC-LPDQQ-----PIPTETFQVADRHPEVAQRV 377
R K S +P PRPG C P Q +P + HP + + V
Sbjct: 350 GRFREQKSPESIWTPVPEDQVPRPRPGCCAAPGMQYNASSALPDDILNFVKTHPLMDEAV 409
Query: 378 EPMGP----LKTPLFHSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHK-VVEPGEQ- 431
+G L+T + H +VAV G V++L ++ GT+ K +V P
Sbjct: 410 PSLGHAPWILRTLMRH---QLTRVAVDVGAGPWGNQ-TVVFLGSEAGTVLKFLVRPNAST 465
Query: 432 --EHSFAFNIMEIQPFR-----------RAAAIQTMSLDAERRKLYVSSQWEVSQVPLDL 478
+ + E + +R + ++ LDA L + V +VP+
Sbjct: 466 SGTSGLSVFLEEFETYRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVAR 525
Query: 479 CEVYGGGCHGCLMSRDPYCGW-DQGRCISIYSSERSVLQ 516
C+ Y G C+ S+DPYCGW G CI + R+ +
Sbjct: 526 CQQYSGCMKNCIGSQDPYCGWAPDGSCIFLSPGTRAAFE 564
>gi|24234732 semaphorin 6D isoform 6 precursor [Homo sapiens]
Length = 476
Score = 95.1 bits (235), Expect = 2e-19
Identities = 96/346 (27%), Positives = 150/346 (43%), Gaps = 36/346 (10%)
Query: 109 RTDCENYITL-LERRSEGLLACGTNARHPSCWNLVNGTVVPLGE-MRGYA--PFSPDENS 164
+ +C N+I + + R E + CGTNA +P C T+ GE + G A PF + +
Sbjct: 115 KDECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEYDGEEISGLARCPFDARQTN 174
Query: 165 LVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQDQAYDD 224
+ LF ++YS +R + S L T + + ++IK Y +
Sbjct: 175 VALFADGKLYSATVADFLASDAVIYRSMGDGSALRT---IKYDSKWIKEPHFLHAIEYGN 231
Query: 225 KIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKAMLVCSDAATN- 283
+Y+FFRE + N SRVA++C+ D GG + W +FLKA L CS +
Sbjct: 232 YVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGDSF 291
Query: 284 KNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY---SAVCVYSLGDIDKVF--RTSSLK 338
F+ LQ + + +G V GVF+ N SAVC +S+ DI+KVF R K
Sbjct: 292 FYFDVLQSITDIIQING---IPTVVGVFTTQLNSIPGSAVCAFSMDDIEKVFKGRFKEQK 348
Query: 339 GYHS--------SLPNPRPGKC--------LPDQQPIPTETFQVADRHPEVAQRVEPMGP 382
S +P PRPG C P ET HP + V P+
Sbjct: 349 TPDSVWTAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPPIA- 407
Query: 383 LKTPLF-HSKYHYQKVAVH-RMQASHGETFHVLYLTTDRGTIHKVV 426
P F ++ Y+ A+ A + + V+++ ++ G + KV+
Sbjct: 408 -DEPWFTKTRVRYRLTAISVDHSAGPYQNYTVIFVGSEAGMVLKVL 452
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.433
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,986,913
Number of Sequences: 37866
Number of extensions: 1511608
Number of successful extensions: 6945
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 6658
Number of HSP's gapped (non-prelim): 135
length of query: 652
length of database: 18,247,518
effective HSP length: 109
effective length of query: 543
effective length of database: 14,120,124
effective search space: 7667227332
effective search space used: 7667227332
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.