Search of human proteins with 225637459

Search of human proteins with 225637459

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|225637459 transketolase-like 1 isoform a [Homo sapiens]
         (596 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|225637459 transketolase-like 1 isoform a [Homo sapiens]           1190   0.0  
gi|225637461 transketolase-like 1 isoform b [Homo sapiens]           1169   0.0  
gi|225637463 transketolase-like 1 isoform c [Homo sapiens]           1082   0.0  
gi|133778974 transketolase-like 2 [Homo sapiens]                      892   0.0  
gi|205277463 transketolase isoform 1 [Homo sapiens]                   736   0.0  
gi|4507521 transketolase isoform 1 [Homo sapiens]                     736   0.0  
gi|205277465 transketolase isoform 2 [Homo sapiens]                   665   0.0  
gi|156564403 pyruvate dehydrogenase (lipoamide) beta [Homo sapiens]    60   4e-09
gi|4557353 branched chain keto acid dehydrogenase E1 beta precur...    43   0.001
gi|34101272 branched chain keto acid dehydrogenase E1 beta precu...    43   0.001
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof...    32   2.2  
gi|33624873 spectrin repeat containing, nuclear envelope 2 isofo...    32   2.2  
gi|62860046 zinc finger, RAN-binding domain containing 3 [Homo s...    30   6.3  
gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]    30   8.2  
gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens]     30   8.2  
gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens]     30   8.2  
gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens]    30   8.2  

>gi|225637459 transketolase-like 1 isoform a [Homo sapiens]
          Length = 596

 Score = 1190 bits (3079), Expect = 0.0
 Identities = 596/596 (100%), Positives = 596/596 (100%)

Query: 1   MADAEARAEFPEEARPDRGTLQVLQDMASRLRIHSIRATCSTSSGHPTSCSSSSEIMSVL 60
           MADAEARAEFPEEARPDRGTLQVLQDMASRLRIHSIRATCSTSSGHPTSCSSSSEIMSVL
Sbjct: 1   MADAEARAEFPEEARPDRGTLQVLQDMASRLRIHSIRATCSTSSGHPTSCSSSSEIMSVL 60

Query: 61  FFYIMRYKQSDPENPDNDRFVLAKRLSFVDVATGWLGQGLGVACGMAYTGKYFDRASYRV 120
           FFYIMRYKQSDPENPDNDRFVLAKRLSFVDVATGWLGQGLGVACGMAYTGKYFDRASYRV
Sbjct: 61  FFYIMRYKQSDPENPDNDRFVLAKRLSFVDVATGWLGQGLGVACGMAYTGKYFDRASYRV 120

Query: 121 FCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRRCEAF 180
           FCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRRCEAF
Sbjct: 121 FCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRRCEAF 180

Query: 181 GWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPMPRER 240
           GWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPMPRER
Sbjct: 181 GWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPMPRER 240

Query: 241 ADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACGLALA 300
           ADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACGLALA
Sbjct: 241 ADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACGLALA 300

Query: 301 KLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRTIAFA 360
           KLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRTIAFA
Sbjct: 301 KLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRTIAFA 360

Query: 361 STFAAFLTRAFDHIRIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIF 420
           STFAAFLTRAFDHIRIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIF
Sbjct: 361 STFAAFLTRAFDHIRIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIF 420

Query: 421 YPTDAVSTEHAVALAANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDKVTVI 480
           YPTDAVSTEHAVALAANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDKVTVI
Sbjct: 421 YPTDAVSTEHAVALAANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDKVTVI 480

Query: 481 GAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQG 540
           GAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQG
Sbjct: 481 GAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQG 540

Query: 541 GIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCMLLN 596
           GIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCMLLN
Sbjct: 541 GIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCMLLN 596


>gi|225637461 transketolase-like 1 isoform b [Homo sapiens]
          Length = 590

 Score = 1169 bits (3025), Expect = 0.0
 Identities = 590/596 (98%), Positives = 590/596 (98%), Gaps = 6/596 (1%)

Query: 1   MADAEARAEFPEEARPDRGTLQVLQDMASRLRIHSIRATCSTSSGHPTSCSSSSEIMSVL 60
           MADAEARAEFPEEARPDRGTLQVLQDMASRLRIHSIRATCSTSSG      SSSEIMSVL
Sbjct: 1   MADAEARAEFPEEARPDRGTLQVLQDMASRLRIHSIRATCSTSSG------SSSEIMSVL 54

Query: 61  FFYIMRYKQSDPENPDNDRFVLAKRLSFVDVATGWLGQGLGVACGMAYTGKYFDRASYRV 120
           FFYIMRYKQSDPENPDNDRFVLAKRLSFVDVATGWLGQGLGVACGMAYTGKYFDRASYRV
Sbjct: 55  FFYIMRYKQSDPENPDNDRFVLAKRLSFVDVATGWLGQGLGVACGMAYTGKYFDRASYRV 114

Query: 121 FCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRRCEAF 180
           FCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRRCEAF
Sbjct: 115 FCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRRCEAF 174

Query: 181 GWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPMPRER 240
           GWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPMPRER
Sbjct: 175 GWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPMPRER 234

Query: 241 ADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACGLALA 300
           ADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACGLALA
Sbjct: 235 ADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACGLALA 294

Query: 301 KLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRTIAFA 360
           KLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRTIAFA
Sbjct: 295 KLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRTIAFA 354

Query: 361 STFAAFLTRAFDHIRIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIF 420
           STFAAFLTRAFDHIRIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIF
Sbjct: 355 STFAAFLTRAFDHIRIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIF 414

Query: 421 YPTDAVSTEHAVALAANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDKVTVI 480
           YPTDAVSTEHAVALAANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDKVTVI
Sbjct: 415 YPTDAVSTEHAVALAANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDKVTVI 474

Query: 481 GAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQG 540
           GAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQG
Sbjct: 475 GAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQG 534

Query: 541 GIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCMLLN 596
           GIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCMLLN
Sbjct: 535 GIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCMLLN 590


>gi|225637463 transketolase-like 1 isoform c [Homo sapiens]
          Length = 540

 Score = 1082 bits (2797), Expect = 0.0
 Identities = 540/540 (100%), Positives = 540/540 (100%)

Query: 57  MSVLFFYIMRYKQSDPENPDNDRFVLAKRLSFVDVATGWLGQGLGVACGMAYTGKYFDRA 116
           MSVLFFYIMRYKQSDPENPDNDRFVLAKRLSFVDVATGWLGQGLGVACGMAYTGKYFDRA
Sbjct: 1   MSVLFFYIMRYKQSDPENPDNDRFVLAKRLSFVDVATGWLGQGLGVACGMAYTGKYFDRA 60

Query: 117 SYRVFCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRR 176
           SYRVFCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRR
Sbjct: 61  SYRVFCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRR 120

Query: 177 CEAFGWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPM 236
           CEAFGWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPM
Sbjct: 121 CEAFGWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPM 180

Query: 237 PRERADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACG 296
           PRERADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACG
Sbjct: 181 PRERADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACG 240

Query: 297 LALAKLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRT 356
           LALAKLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRT
Sbjct: 241 LALAKLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRT 300

Query: 357 IAFASTFAAFLTRAFDHIRIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPK 416
           IAFASTFAAFLTRAFDHIRIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPK
Sbjct: 301 IAFASTFAAFLTRAFDHIRIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPK 360

Query: 417 CTIFYPTDAVSTEHAVALAANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDK 476
           CTIFYPTDAVSTEHAVALAANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDK
Sbjct: 361 CTIFYPTDAVSTEHAVALAANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDK 420

Query: 477 VTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDH 536
           VTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDH
Sbjct: 421 VTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDH 480

Query: 537 YPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCMLLN 596
           YPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCMLLN
Sbjct: 481 YPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCMLLN 540


>gi|133778974 transketolase-like 2 [Homo sapiens]
          Length = 626

 Score =  892 bits (2304), Expect = 0.0
 Identities = 438/621 (70%), Positives = 513/621 (82%), Gaps = 38/621 (6%)

Query: 13  EARPDRGTLQVLQDMASRLRIHSIRATCSTSSGHPTSCSSSSEIMSVLFFYIMRYKQSDP 72
           +A+PD  T+QVL+D A+RLRIHSIRATC++ SG  TSC S++E++SVLFF+ M+YKQ+DP
Sbjct: 5   DAKPDVKTVQVLRDTANRLRIHSIRATCASGSGQLTSCCSAAEVVSVLFFHTMKYKQTDP 64

Query: 73  ENPDNDRFVLAK--------------------------------------RLSFVDVATG 94
           E+PDNDRF+L++                                      RL FVDVATG
Sbjct: 65  EHPDNDRFILSRGHAAPILYAAWVEVGDISESDLLNLRKLHSDLERHPTPRLPFVDVATG 124

Query: 95  WLGQGLGVACGMAYTGKYFDRASYRVFCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFD 154
            LGQGLG ACGMAYTGKY D+ASYRVFCLM DGESSEGSVWEA AFAS+Y+LDNLVA+FD
Sbjct: 125 SLGQGLGTACGMAYTGKYLDKASYRVFCLMGDGESSEGSVWEAFAFASHYNLDNLVAVFD 184

Query: 155 VNRLGHSGALPAEHCINIYQRRCEAFGWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVA 214
           VNRLG SG  P EH  +IYQ  CEAFGWNTY+VDG DVEALCQ FWQASQVK+KPTA+VA
Sbjct: 185 VNRLGQSGPAPLEHGADIYQNCCEAFGWNTYLVDGHDVEALCQAFWQASQVKNKPTAIVA 244

Query: 215 KTFKGRGTPSIEDAESWHAKPMPRERADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITD 274
           KTFKGRG P+IEDAE+WH KP+P+ERADAI+KLIESQIQT+ NL P+ P+EDSP+++ITD
Sbjct: 245 KTFKGRGIPNIEDAENWHGKPVPKERADAIVKLIESQIQTNENLIPKSPVEDSPQISITD 304

Query: 275 VRMTSPPDYRVGDKIATRKACGLALAKLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFI 334
           ++MTSPP Y+VGDKIAT+K  GLALAKLG AN RV+VL GDT  STFSEIF KE+PERFI
Sbjct: 305 IKMTSPPAYKVGDKIATQKTYGLALAKLGRANERVIVLSGDTMNSTFSEIFRKEHPERFI 364

Query: 335 ECFMAEQNMVSVALGCASRGRTIAFASTFAAFLTRAFDHIRIGGLAESNINIIGSHCGVS 394
           EC +AEQNMVSVALGCA+RGRTIAFA  FAAF TRAFD +R+G ++++NIN+IGSHCGVS
Sbjct: 365 ECIIAEQNMVSVALGCATRGRTIAFAGAFAAFFTRAFDQLRMGAISQANINLIGSHCGVS 424

Query: 395 VGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVALAANAKGMCFIRTTRPETMVI 454
            G+DG SQMALED+AMFR+IP CT+FYP+DA+STEHA+ LAAN KGMCFIRT++PET VI
Sbjct: 425 TGEDGVSQMALEDLAMFRSIPNCTVFYPSDAISTEHAIYLAANTKGMCFIRTSQPETAVI 484

Query: 455 YTPQERFEIGQAKVLRHCVSDKVTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPL 514
           YTPQE FEIGQAKV+RH V+DKVTVIGAG+T++EAL AAD LS+Q I +RVID FTIKPL
Sbjct: 485 YTPQENFEIGQAKVVRHGVNDKVTVIGAGVTLHEALEAADHLSQQGISVRVIDPFTIKPL 544

Query: 515 DVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEE 574
           D ATI+SSAKAT GR+ITVEDHY +GGIGEAVCAAVS +PDI VH LAVSGVPQ GK+ E
Sbjct: 545 DAATIISSAKATGGRVITVEDHYREGGIGEAVCAAVSREPDILVHQLAVSGVPQRGKTSE 604

Query: 575 LLDMYGISARHIIVAVKCMLL 595
           LLDM+GIS RHII AV   L+
Sbjct: 605 LLDMFGISTRHIIAAVTLTLM 625


>gi|205277463 transketolase isoform 1 [Homo sapiens]
          Length = 623

 Score =  736 bits (1900), Expect = 0.0
 Identities = 369/618 (59%), Positives = 461/618 (74%), Gaps = 41/618 (6%)

Query: 15  RPDRGTLQVLQDMASRLRIHSIRATCSTSSGHPTSCSSSSEIMSVLFFYIMRYKQSDPEN 74
           +PD+  LQ L+D A+RLRI SI+AT +  SGHPTSC S++EIM+VLFF+ MRYK  DP N
Sbjct: 6   KPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRN 65

Query: 75  PDNDRFVLAK--------------------------------------RLSFVDVATGWL 96
           P NDRFVL+K                                      + +F DVATG L
Sbjct: 66  PHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDVATGSL 125

Query: 97  GQGLGVACGMAYTGKYFDRASYRVFCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVN 156
           GQGLG ACGMAYTGKYFD+ASYRV+CL+ DGE SEGSVWEAMAFAS Y LDNLVAI D+N
Sbjct: 126 GQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDIN 185

Query: 157 RLGHSGALPAEHCINIYQRRCEAFGWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVAKT 216
           RLG S   P +H ++IYQ+RCEAFGW+  +VDG  VE LC+ F QA   KH+PTA++AKT
Sbjct: 186 RLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQA---KHQPTAIIAKT 242

Query: 217 FKGRGTPSIEDAESWHAKPMPRERADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITDVR 276
           FKGRG   +ED ESWH KP+P+  A+ II+ I SQIQ+ + +   PP ED+P V+I ++R
Sbjct: 243 FKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIR 302

Query: 277 MTSPPDYRVGDKIATRKACGLALAKLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFIEC 336
           M S P Y+VGDKIATRKA G ALAKLG+A++R++ LDGDT+ STFSEIF KE+P+RFIEC
Sbjct: 303 MPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIEC 362

Query: 337 FMAEQNMVSVALGCASRGRTIAFASTFAAFLTRAFDHIRIGGLAESNINIIGSHCGVSVG 396
           ++AEQNMVS+A+GCA+R RT+ F STFAAF TRAFD IR+  ++ESNIN+ GSHCGVS+G
Sbjct: 363 YIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIG 422

Query: 397 DDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVALAANAKGMCFIRTTRPETMVIYT 456
           +DG SQMALED+AMFR++P  T+FYP+D V+TE AV LAAN KG+CFIRT+RPE  +IY 
Sbjct: 423 EDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYN 482

Query: 457 PQERFEIGQAKVLRHCVSDKVTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDV 516
             E F++GQAKV+     D+VTVIGAG+T++EALAAA+ L K+ I IRV+D FTIKPLD 
Sbjct: 483 NNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDR 542

Query: 517 ATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELL 576
             I+ SA+AT+GRI+TVEDHY +GGIGEAV +AV  +P I V  LAV+ VP+SGK  ELL
Sbjct: 543 KLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELL 602

Query: 577 DMYGISARHIIVAVKCML 594
            M+GI    I  AV+ ++
Sbjct: 603 KMFGIDRDAIAQAVRGLI 620


>gi|4507521 transketolase isoform 1 [Homo sapiens]
          Length = 623

 Score =  736 bits (1900), Expect = 0.0
 Identities = 369/618 (59%), Positives = 461/618 (74%), Gaps = 41/618 (6%)

Query: 15  RPDRGTLQVLQDMASRLRIHSIRATCSTSSGHPTSCSSSSEIMSVLFFYIMRYKQSDPEN 74
           +PD+  LQ L+D A+RLRI SI+AT +  SGHPTSC S++EIM+VLFF+ MRYK  DP N
Sbjct: 6   KPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRN 65

Query: 75  PDNDRFVLAK--------------------------------------RLSFVDVATGWL 96
           P NDRFVL+K                                      + +F DVATG L
Sbjct: 66  PHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDVATGSL 125

Query: 97  GQGLGVACGMAYTGKYFDRASYRVFCLMSDGESSEGSVWEAMAFASYYSLDNLVAIFDVN 156
           GQGLG ACGMAYTGKYFD+ASYRV+CL+ DGE SEGSVWEAMAFAS Y LDNLVAI D+N
Sbjct: 126 GQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDIN 185

Query: 157 RLGHSGALPAEHCINIYQRRCEAFGWNTYVVDGRDVEALCQVFWQASQVKHKPTAVVAKT 216
           RLG S   P +H ++IYQ+RCEAFGW+  +VDG  VE LC+ F QA   KH+PTA++AKT
Sbjct: 186 RLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQA---KHQPTAIIAKT 242

Query: 217 FKGRGTPSIEDAESWHAKPMPRERADAIIKLIESQIQTSRNLDPQPPIEDSPEVNITDVR 276
           FKGRG   +ED ESWH KP+P+  A+ II+ I SQIQ+ + +   PP ED+P V+I ++R
Sbjct: 243 FKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIR 302

Query: 277 MTSPPDYRVGDKIATRKACGLALAKLGYANNRVVVLDGDTRYSTFSEIFNKEYPERFIEC 336
           M S P Y+VGDKIATRKA G ALAKLG+A++R++ LDGDT+ STFSEIF KE+P+RFIEC
Sbjct: 303 MPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIEC 362

Query: 337 FMAEQNMVSVALGCASRGRTIAFASTFAAFLTRAFDHIRIGGLAESNINIIGSHCGVSVG 396
           ++AEQNMVS+A+GCA+R RT+ F STFAAF TRAFD IR+  ++ESNIN+ GSHCGVS+G
Sbjct: 363 YIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIG 422

Query: 397 DDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVALAANAKGMCFIRTTRPETMVIYT 456
           +DG SQMALED+AMFR++P  T+FYP+D V+TE AV LAAN KG+CFIRT+RPE  +IY 
Sbjct: 423 EDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYN 482

Query: 457 PQERFEIGQAKVLRHCVSDKVTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDV 516
             E F++GQAKV+     D+VTVIGAG+T++EALAAA+ L K+ I IRV+D FTIKPLD 
Sbjct: 483 NNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDR 542

Query: 517 ATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAVSMDPDIQVHSLAVSGVPQSGKSEELL 576
             I+ SA+AT+GRI+TVEDHY +GGIGEAV +AV  +P I V  LAV+ VP+SGK  ELL
Sbjct: 543 KLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELL 602

Query: 577 DMYGISARHIIVAVKCML 594
            M+GI    I  AV+ ++
Sbjct: 603 KMFGIDRDAIAQAVRGLI 620


>gi|205277465 transketolase isoform 2 [Homo sapiens]
          Length = 540

 Score =  665 bits (1715), Expect = 0.0
 Identities = 336/580 (57%), Positives = 425/580 (73%), Gaps = 48/580 (8%)

Query: 15  RPDRGTLQVLQDMASRLRIHSIRATCSTSSGHPTSCSSSSEIMSVLFFYIMRYKQSDPEN 74
           +PD+  LQ L+D A+RLRI SI+AT +  SGHPTSC S++EIM+VLFF+           
Sbjct: 6   KPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFH----------- 54

Query: 75  PDNDRFVLAKRLSFVDVATGWLGQGLGVACGMAYTGKYFDRASYRVFCLMSDGESSEGSV 134
                                             TGKYFD+ASYRV+CL+ DGE SEGSV
Sbjct: 55  ----------------------------------TGKYFDKASYRVYCLLGDGELSEGSV 80

Query: 135 WEAMAFASYYSLDNLVAIFDVNRLGHSGALPAEHCINIYQRRCEAFGWNTYVVDGRDVEA 194
           WEAMAFAS Y LDNLVAI D+NRLG S   P +H ++IYQ+RCEAFGW+  +VDG  VE 
Sbjct: 81  WEAMAFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEE 140

Query: 195 LCQVFWQASQVKHKPTAVVAKTFKGRGTPSIEDAESWHAKPMPRERADAIIKLIESQIQT 254
           LC+ F QA   KH+PTA++AKTFKGRG   +ED ESWH KP+P+  A+ II+ I SQIQ+
Sbjct: 141 LCKAFGQA---KHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQS 197

Query: 255 SRNLDPQPPIEDSPEVNITDVRMTSPPDYRVGDKIATRKACGLALAKLGYANNRVVVLDG 314
            + +   PP ED+P V+I ++RM S P Y+VGDKIATRKA G ALAKLG+A++R++ LDG
Sbjct: 198 KKKILATPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDG 257

Query: 315 DTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRGRTIAFASTFAAFLTRAFDHI 374
           DT+ STFSEIF KE+P+RFIEC++AEQNMVS+A+GCA+R RT+ F STFAAF TRAFD I
Sbjct: 258 DTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQI 317

Query: 375 RIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVAL 434
           R+  ++ESNIN+ GSHCGVS+G+DG SQMALED+AMFR++P  T+FYP+D V+TE AV L
Sbjct: 318 RMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVEL 377

Query: 435 AANAKGMCFIRTTRPETMVIYTPQERFEIGQAKVLRHCVSDKVTVIGAGITVYEALAAAD 494
           AAN KG+CFIRT+RPE  +IY   E F++GQAKV+     D+VTVIGAG+T++EALAAA+
Sbjct: 378 AANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAE 437

Query: 495 ELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAVSMDP 554
            L K+ I IRV+D FTIKPLD   I+ SA+AT+GRI+TVEDHY +GGIGEAV +AV  +P
Sbjct: 438 LLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEP 497

Query: 555 DIQVHSLAVSGVPQSGKSEELLDMYGISARHIIVAVKCML 594
            I V  LAV+ VP+SGK  ELL M+GI    I  AV+ ++
Sbjct: 498 GITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQAVRGLI 537


>gi|156564403 pyruvate dehydrogenase (lipoamide) beta [Homo sapiens]
          Length = 359

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 82/306 (26%), Positives = 129/306 (42%), Gaps = 44/306 (14%)

Query: 315 DTRYSTFSEIFNKEYPERFIECFMAEQNMVSVALGCASRG-RTIAFASTFAAFLTRAFDH 373
           D  Y     ++ K   +R I+  ++E     +A+G A  G R I    TF  F  +A D 
Sbjct: 64  DGAYKVSRGLWKKYGDKRIIDTPISEMGFAGIAVGAAMAGLRPICEFMTFN-FSMQAIDQ 122

Query: 374 I---------RIGGLAESNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIFYPTD 424
           +           GGL    I   G + G S G   A+Q +    A +   P   +  P +
Sbjct: 123 VINSAAKTYYMSGGLQPVPIVFRGPN-GASAGV--AAQHSQCFAAWYGHCPGLKVVSPWN 179

Query: 425 AVSTEHAVALAANAKGMCFIRTTRP----ETMVIYTPQERFE-----------IGQAKVL 469
           +   E A  L  +A     IR   P    E  ++Y     F            IG+AK+ 
Sbjct: 180 S---EDAKGLIKSA-----IRDNNPVVVLENELMYGVPFEFPPEAQSKDFLIPIGKAKIE 231

Query: 470 RHCVSDKVTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGR 529
           R      +TV+     V   L AA  LSK+ +   VI++ TI+P+D+ TI +S   T   
Sbjct: 232 RQ--GTHITVVSHSRPVGHCLEAAAVLSKEGVECEVINMRTIRPMDMETIEASVMKT-NH 288

Query: 530 IITVEDHYPQGGIGEAVCAAVSMDPD---IQVHSLAVSGVPQSGKSEELLDMYGI-SARH 585
           ++TVE  +PQ G+G  +CA +   P    +   ++ V+G        ++L+   I   + 
Sbjct: 289 LVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTGADVPMPYAKILEDNSIPQVKD 348

Query: 586 IIVAVK 591
           II A+K
Sbjct: 349 IIFAIK 354


>gi|4557353 branched chain keto acid dehydrogenase E1 beta precursor
           [Homo sapiens]
          Length = 392

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 64/240 (26%), Positives = 90/240 (37%), Gaps = 31/240 (12%)

Query: 331 ERFIECFMAEQNMVSVALGCASRGRTIAFASTFAAFLTRAFDHI---------RIGGLAE 381
           +R     + EQ +V   +G A  G T      FA ++  AFD I         R G L  
Sbjct: 117 DRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFN 176

Query: 382 SNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVALAANAKGM 441
                I S  G  VG  GA   +    A F   P   +  P      +  +      K  
Sbjct: 177 CGSLTIRSPWGC-VGH-GALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNP 234

Query: 442 CFIRTTRPETMVIY------TPQERFEI--GQAKVLRHCVSDKVTVIGAGITVY---EAL 490
           C       E  ++Y       P E + I   QA+V++      VT++  G  V+   E  
Sbjct: 235 CIFF----EPKILYRAAAEEVPIEPYNIPLSQAEVIQE--GSDVTLVAWGTQVHVIREVA 288

Query: 491 AAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAV 550
           + A E  K  +   VIDL TI P DV TI  S   T GR++   +    GG    + + V
Sbjct: 289 SMAKE--KLGVSCEVIDLRTIIPWDVDTICKSVIKT-GRLLISHEAPLTGGFASEISSTV 345


>gi|34101272 branched chain keto acid dehydrogenase E1 beta
           precursor [Homo sapiens]
          Length = 392

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 64/240 (26%), Positives = 90/240 (37%), Gaps = 31/240 (12%)

Query: 331 ERFIECFMAEQNMVSVALGCASRGRTIAFASTFAAFLTRAFDHI---------RIGGLAE 381
           +R     + EQ +V   +G A  G T      FA ++  AFD I         R G L  
Sbjct: 117 DRVFNTPLCEQGIVGFGIGIAVTGATAIAEIQFADYIFPAFDQIVNEAAKYRYRSGDLFN 176

Query: 382 SNINIIGSHCGVSVGDDGASQMALEDIAMFRTIPKCTIFYPTDAVSTEHAVALAANAKGM 441
                I S  G  VG  GA   +    A F   P   +  P      +  +      K  
Sbjct: 177 CGSLTIRSPWGC-VGH-GALYHSQSPEAFFAHCPGIKVVIPRSPFQAKGLLLSCIEDKNP 234

Query: 442 CFIRTTRPETMVIY------TPQERFEI--GQAKVLRHCVSDKVTVIGAGITVY---EAL 490
           C       E  ++Y       P E + I   QA+V++      VT++  G  V+   E  
Sbjct: 235 CIFF----EPKILYRAAAEEVPIEPYNIPLSQAEVIQE--GSDVTLVAWGTQVHVIREVA 288

Query: 491 AAADELSKQDIFIRVIDLFTIKPLDVATIVSSAKATEGRIITVEDHYPQGGIGEAVCAAV 550
           + A E  K  +   VIDL TI P DV TI  S   T GR++   +    GG    + + V
Sbjct: 289 SMAKE--KLGVSCEVIDLRTIIPWDVDTICKSVIKT-GRLLISHEAPLTGGFASEISSTV 345


>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
            [Homo sapiens]
          Length = 6907

 Score = 31.6 bits (70), Expect = 2.2
 Identities = 17/57 (29%), Positives = 24/57 (42%), Gaps = 5/57 (8%)

Query: 212  VVAKTFKGRGTPSIEDAESWHAKPMPRERADAIIKLIESQIQTSRNLDPQPPIEDSP 268
            +  KT K     SI D  SWH    P     +  +    Q++  RN+ P PP   +P
Sbjct: 6458 MTTKTLKASSGKSISDGHSWHVPDSP-----SCPEHHYKQMEGDRNVPPVPPASSTP 6509


>gi|33624873 spectrin repeat containing, nuclear envelope 2 isoform
           4 [Homo sapiens]
          Length = 556

 Score = 31.6 bits (70), Expect = 2.2
 Identities = 17/57 (29%), Positives = 24/57 (42%), Gaps = 5/57 (8%)

Query: 212 VVAKTFKGRGTPSIEDAESWHAKPMPRERADAIIKLIESQIQTSRNLDPQPPIEDSP 268
           +  KT K     SI D  SWH    P     +  +    Q++  RN+ P PP   +P
Sbjct: 92  MTTKTLKASSGKSISDGHSWHVPDSP-----SCPEHHYKQMEGDRNVPPVPPASSTP 143


>gi|62860046 zinc finger, RAN-binding domain containing 3 [Homo
           sapiens]
          Length = 1079

 Score = 30.0 bits (66), Expect = 6.3
 Identities = 21/76 (27%), Positives = 35/76 (46%), Gaps = 8/76 (10%)

Query: 456 TPQERFEIGQAKVLRHCVSDKVTVIGAGITVYEALAAADELSKQDIFIRVIDLFTIKPLD 515
           +P+E   I     +R   + KVTV+G G+   +A    D L+ Q+        F +  +D
Sbjct: 106 SPEEINVIQNKTDVRRMSTSKVTVLGYGLLTADAKTLIDALNNQN--------FKVVIVD 157

Query: 516 VATIVSSAKATEGRII 531
            +  + S  AT  RI+
Sbjct: 158 ESHYMKSRNATRSRIL 173


>gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]
          Length = 1126

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 13/47 (27%), Positives = 23/47 (48%)

Query: 221  GTPSIEDAESWHAKPMPRERADAIIKLIESQIQTSRNLDPQPPIEDS 267
            G+   +D  S   +P         + +I+  IQ+ R + PQPP+ D+
Sbjct: 989  GSRDEQDGASAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDA 1035


>gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens]
          Length = 1126

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 13/47 (27%), Positives = 23/47 (48%)

Query: 221  GTPSIEDAESWHAKPMPRERADAIIKLIESQIQTSRNLDPQPPIEDS 267
            G+   +D  S   +P         + +I+  IQ+ R + PQPP+ D+
Sbjct: 989  GSRDEQDGASAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDA 1035


>gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens]
          Length = 1126

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 13/47 (27%), Positives = 23/47 (48%)

Query: 221  GTPSIEDAESWHAKPMPRERADAIIKLIESQIQTSRNLDPQPPIEDS 267
            G+   +D  S   +P         + +I+  IQ+ R + PQPP+ D+
Sbjct: 989  GSRDEQDGASAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDA 1035


>gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens]
          Length = 1132

 Score = 29.6 bits (65), Expect = 8.2
 Identities = 13/47 (27%), Positives = 23/47 (48%)

Query: 221  GTPSIEDAESWHAKPMPRERADAIIKLIESQIQTSRNLDPQPPIEDS 267
            G+   +D  S   +P         + +I+  IQ+ R + PQPP+ D+
Sbjct: 995  GSRDEQDGASAETEPWAAAVPPEWVPIIQQDIQSQRKVKPQPPLSDA 1041


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.134    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,260,194
Number of Sequences: 37866
Number of extensions: 900712
Number of successful extensions: 1989
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1967
Number of HSP's gapped (non-prelim): 22
length of query: 596
length of database: 18,247,518
effective HSP length: 108
effective length of query: 488
effective length of database: 14,157,990
effective search space: 6909099120
effective search space used: 6909099120
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.