Search of human proteins with 224831257

Search of human proteins with 224831257

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|224831257 importin 13 [Homo sapiens]
         (963 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|224831257 importin 13 [Homo sapiens]                              1914   0.0  
gi|6912734 transportin 3 [Homo sapiens]                               200   6e-51
gi|4507943 exportin 1 [Homo sapiens]                                   72   3e-12
gi|53759103 importin 8 [Homo sapiens]                                  40   0.014
gi|62460637 importin 4 [Homo sapiens]                                  38   0.040
gi|8051636 tRNA exportin [Homo sapiens]                                37   0.12 
gi|148886661 exportin 4 [Homo sapiens]                                 33   1.3  
gi|51558724 ADAM metallopeptidase with thrombospondin type 1 mot...    31   4.9  
gi|239753475 PREDICTED: hypothetical protein [Homo sapiens]            31   6.4  
gi|239748044 PREDICTED: hypothetical protein XP_002346500 [Homo ...    31   6.4  
gi|239741935 PREDICTED: hypothetical protein XP_002342357 [Homo ...    31   6.4  
gi|11386135 branched chain keto acid dehydrogenase E1, alpha pol...    30   8.3  

>gi|224831257 importin 13 [Homo sapiens]
          Length = 963

 Score = 1914 bits (4958), Expect = 0.0
 Identities = 963/963 (100%), Positives = 963/963 (100%)

Query: 1   MERREEQPGAAGAGAAPALDFTVENVEKALHQLYYDPNIENKNLAQKWLMQAQVSPQAWH 60
           MERREEQPGAAGAGAAPALDFTVENVEKALHQLYYDPNIENKNLAQKWLMQAQVSPQAWH
Sbjct: 1   MERREEQPGAAGAGAAPALDFTVENVEKALHQLYYDPNIENKNLAQKWLMQAQVSPQAWH 60

Query: 61  FSWQLLQPDKVPEIQYFGASALHIKISRYWSDIPTDQYESLKAQLFTQITRFASGSKIVL 120
           FSWQLLQPDKVPEIQYFGASALHIKISRYWSDIPTDQYESLKAQLFTQITRFASGSKIVL
Sbjct: 61  FSWQLLQPDKVPEIQYFGASALHIKISRYWSDIPTDQYESLKAQLFTQITRFASGSKIVL 120

Query: 121 TRLCVALASLALSMMPDAWPCAVADMVRLFQAEDSPVDGQGRCLALLELLTVLPEEFQTS 180
           TRLCVALASLALSMMPDAWPCAVADMVRLFQAEDSPVDGQGRCLALLELLTVLPEEFQTS
Sbjct: 121 TRLCVALASLALSMMPDAWPCAVADMVRLFQAEDSPVDGQGRCLALLELLTVLPEEFQTS 180

Query: 181 RLPQYRKGLVRTSLAVECGAVFPLLEQLLQQPSSPSCVRQKVLKCFSSWVQLEVPLQDCE 240
           RLPQYRKGLVRTSLAVECGAVFPLLEQLLQQPSSPSCVRQKVLKCFSSWVQLEVPLQDCE
Sbjct: 181 RLPQYRKGLVRTSLAVECGAVFPLLEQLLQQPSSPSCVRQKVLKCFSSWVQLEVPLQDCE 240

Query: 241 ALIQAAFAALQDSELFDSSVEAIVNAISQPDAQRYVNTLLKLIPLVLGLQEQLRQAVQNG 300
           ALIQAAFAALQDSELFDSSVEAIVNAISQPDAQRYVNTLLKLIPLVLGLQEQLRQAVQNG
Sbjct: 241 ALIQAAFAALQDSELFDSSVEAIVNAISQPDAQRYVNTLLKLIPLVLGLQEQLRQAVQNG 300

Query: 301 DMETSHGICRIAVALGENHSRALLDQVEHWQSFLALVNMIMFCTGIPGHYPVNETTSSLT 360
           DMETSHGICRIAVALGENHSRALLDQVEHWQSFLALVNMIMFCTGIPGHYPVNETTSSLT
Sbjct: 301 DMETSHGICRIAVALGENHSRALLDQVEHWQSFLALVNMIMFCTGIPGHYPVNETTSSLT 360

Query: 361 LTFWYTLQDDILSFEAEKQAVYQQVYRPVYFQLVDVLLHKAQFPSDEEYGFWSSDEKEQF 420
           LTFWYTLQDDILSFEAEKQAVYQQVYRPVYFQLVDVLLHKAQFPSDEEYGFWSSDEKEQF
Sbjct: 361 LTFWYTLQDDILSFEAEKQAVYQQVYRPVYFQLVDVLLHKAQFPSDEEYGFWSSDEKEQF 420

Query: 421 RIYRVDISDTLMYVYEMLGAELLSNLYDKLGRLLTSSEEPYSWQHTEALLYGFQSIAETI 480
           RIYRVDISDTLMYVYEMLGAELLSNLYDKLGRLLTSSEEPYSWQHTEALLYGFQSIAETI
Sbjct: 421 RIYRVDISDTLMYVYEMLGAELLSNLYDKLGRLLTSSEEPYSWQHTEALLYGFQSIAETI 480

Query: 481 DVNYSDVVPGLIGLIPRISISNVQLADTVMFTIGALSEWLADHPVMINSVLPLVLHALGN 540
           DVNYSDVVPGLIGLIPRISISNVQLADTVMFTIGALSEWLADHPVMINSVLPLVLHALGN
Sbjct: 481 DVNYSDVVPGLIGLIPRISISNVQLADTVMFTIGALSEWLADHPVMINSVLPLVLHALGN 540

Query: 541 PELSVSSVSTLKKICRECKYDLPPYAANIVAVSQDVLMKQIHKTSQCMWLMQALGFLLSA 600
           PELSVSSVSTLKKICRECKYDLPPYAANIVAVSQDVLMKQIHKTSQCMWLMQALGFLLSA
Sbjct: 541 PELSVSSVSTLKKICRECKYDLPPYAANIVAVSQDVLMKQIHKTSQCMWLMQALGFLLSA 600

Query: 601 LQVEEILKNLHSLISPYIQQLEKLAEEIPNPSNKLAIVHILGLLSNLFTTLDISHHEDDH 660
           LQVEEILKNLHSLISPYIQQLEKLAEEIPNPSNKLAIVHILGLLSNLFTTLDISHHEDDH
Sbjct: 601 LQVEEILKNLHSLISPYIQQLEKLAEEIPNPSNKLAIVHILGLLSNLFTTLDISHHEDDH 660

Query: 661 EGPELRKLPVPQGPNPVVVVLQQVFQLIQKVLSKWLNDAQVVEAVCAIFEKSVKTLLDDF 720
           EGPELRKLPVPQGPNPVVVVLQQVFQLIQKVLSKWLNDAQVVEAVCAIFEKSVKTLLDDF
Sbjct: 661 EGPELRKLPVPQGPNPVVVVLQQVFQLIQKVLSKWLNDAQVVEAVCAIFEKSVKTLLDDF 720

Query: 721 APMVPQLCEMLGRMYSTIPQASALDLTRQLVHIFAHEPAHFPPIEALFLLVTSVTLTLFQ 780
           APMVPQLCEMLGRMYSTIPQASALDLTRQLVHIFAHEPAHFPPIEALFLLVTSVTLTLFQ
Sbjct: 721 APMVPQLCEMLGRMYSTIPQASALDLTRQLVHIFAHEPAHFPPIEALFLLVTSVTLTLFQ 780

Query: 781 QGPRDHPDIVDSFMQLLAQALKRKPDLFLCERLDVKAVFQCAVLALKFPEAPTVKASCGF 840
           QGPRDHPDIVDSFMQLLAQALKRKPDLFLCERLDVKAVFQCAVLALKFPEAPTVKASCGF
Sbjct: 781 QGPRDHPDIVDSFMQLLAQALKRKPDLFLCERLDVKAVFQCAVLALKFPEAPTVKASCGF 840

Query: 841 FTELLPRCGEVESVGKVVQEDGRMLLIAVLEAIGGQASRSLMDCFADILFALNKHCFSLL 900
           FTELLPRCGEVESVGKVVQEDGRMLLIAVLEAIGGQASRSLMDCFADILFALNKHCFSLL
Sbjct: 841 FTELLPRCGEVESVGKVVQEDGRMLLIAVLEAIGGQASRSLMDCFADILFALNKHCFSLL 900

Query: 901 SMWIKEALQPPGFPSARLSPEQKDTFSQQILRERVNKRRVKEMVKEFTLLCRGLHGTDYT 960
           SMWIKEALQPPGFPSARLSPEQKDTFSQQILRERVNKRRVKEMVKEFTLLCRGLHGTDYT
Sbjct: 901 SMWIKEALQPPGFPSARLSPEQKDTFSQQILRERVNKRRVKEMVKEFTLLCRGLHGTDYT 960

Query: 961 ADY 963
           ADY
Sbjct: 961 ADY 963


>gi|6912734 transportin 3 [Homo sapiens]
          Length = 923

 Score =  200 bits (508), Expect = 6e-51
 Identities = 224/970 (23%), Positives = 421/970 (43%), Gaps = 80/970 (8%)

Query: 14  GAAPALDFTVENVEKALHQLYYDPNIENKNLAQKWLMQAQVSPQAWHFSWQLLQPDKVPE 73
           GA P    T++ V +A+  LY+DP+   K  A  WL + Q S  AW  S QLLQ  +  E
Sbjct: 3   GAKP----TLQLVYQAVQALYHDPDPSGKERASFWLGELQRSVHAWEISDQLLQIRQDVE 58

Query: 74  IQYFGASALHIKISRYWSDIPTDQYESLKAQLFTQITRFASGSKIVLTRLCVALASLALS 133
             YF A  + +KI   + ++PTD + SL+  L T I      S +++T+L +A+A LAL 
Sbjct: 59  SCYFAAQTMKMKIQTSFYELPTDSHASLRDSLLTHIQNLKDLSPVIVTQLALAIADLALQ 118

Query: 134 MMPDAWPCAVADMVRLFQAEDSPVDGQGRCLALLELLTVLPEEF--QTSRLPQYRKGLVR 191
           M   +W   V  +V  +  + + +        LLE+LTVLPEE   ++ R+   R+  + 
Sbjct: 119 M--PSWKGCVQTLVEKYSNDVTSLP------FLLEILTVLPEEVHSRSLRIGANRRTEII 170

Query: 192 TSLAVECGAVFPLLEQLLQQPSSPSCVRQKVLKCFSSWVQLEVPLQDCEA---LIQAAFA 248
             LA     V  LL   +++  +   +  KV +C  SW  L V   +  A   L+   F 
Sbjct: 171 EDLAFYSSTVVSLLMTCVEKAGTDEKMLMKVFRCLGSWFNLGVLDSNFMANNKLLALLFE 230

Query: 249 ALQ----DSELFDSSVEAIVNAI-SQPDAQRYVNTLLKLIPLVLGLQEQLRQAVQNGDME 303
            LQ     S L +++ + + +A+ +  + +  +   ++L   VL L+     AV   D++
Sbjct: 231 VLQQDKTSSNLHEAASDCVCSALYAIENVETNLPLAMQLFQGVLTLETAYHMAVAREDLD 290

Query: 304 TSHGICRIAVALGENHSRALLDQVEHWQSFLALVNMIMFCTGIPGHYPVNETTSSLTLTF 363
                CRI   L E     ++         L  + +++ C G P  Y V E    ++  F
Sbjct: 291 KVLNYCRIFTELCETFLEKIVCTPGQGLGDLRTLELLLICAGHP-QYEVVE----ISFNF 345

Query: 364 WYTLQDDILSFEAEKQAVYQQVYRPVYFQLVDVLLHKAQFPSDEEYGFWSSDEKEQFRIY 423
           WY L + +     E   V   +++    +L+  L    Q   D E      +E + F  +
Sbjct: 346 WYRLGEHLYKTNDE---VIHGIFKAYIQRLLHALARHCQLEPDHE---GVPEETDDFGEF 399

Query: 424 RVDISDTLMYVYEMLGA-ELLSNLYDKLGRLLTSSEEPYSWQHTEALLYGFQSIAETID- 481
           R+ +SD +  +  ++G+ E  + LY       T  E    W+ TEA+L+   +IA+++D 
Sbjct: 400 RMRVSDLVKDLIFLIGSMECFAQLYS------TLKEGNPPWEVTEAVLFIMAAIAKSVDP 453

Query: 482 VNYSDVVPGLIGLIPRISISNVQLADTVMFTIGALSEWLADHPVMINSVLPLVLHALGNP 541
            N   +V  L G++      +  +  T +  +G +SE +  +P  ++ VL  ++  L   
Sbjct: 454 ENNPTLVEVLEGVVRLPETVHTAVRYTSIELVGEMSEVVDRNPQFLDPVLGYLMKGLCEK 513

Query: 542 ELSVSSVSTLKKICRECKYDLPPYAANIVAVSQDVLMKQIHKTSQCMWLMQALGFLLSAL 601
            L+ ++   +  IC  C+  +  +   ++ +++  L   +      + L++    +L+ L
Sbjct: 514 PLASAAAKAIHNICSVCRDHMAQHFNGLLEIARS-LDSFLLSPEAAVGLLKGTALVLARL 572

Query: 602 QVEEILKNLHSLISPYIQQLEKLAEEIPNPSNKLAIVHILGLLSNLFTTLDISHHEDDHE 661
            +++I + L  L S  +  L+KL  +   PSN        G+ S+    LD       H 
Sbjct: 573 PLDKITECLSELCSVQVMALKKLLSQ--EPSN--------GISSDPTVFLDRLAVIFRHT 622

Query: 662 GPELRKLPVPQGPNPVVVVLQQVFQLIQKVLSKWLNDAQVVEAVCAIFEKSVKTLLDDFA 721
            P +         +P   V+Q+++ ++ + L+K   D ++VE  C     +V+ +    A
Sbjct: 623 NPIVEN----GQTHPCQKVIQEIWPVLSETLNKHRADNRIVERCCRCLRFAVRCVGKGSA 678

Query: 722 PMVPQLCEMLGRMYSTIPQASALDLTRQLVHIFAHEPAHFPPIEALFLLVTSVTLTLFQQ 781
            ++  L   +  +Y     +  L L   LV  +  E      +  +   +   T  L +Q
Sbjct: 679 ALLQPLVTQMVNVYHVHQHSCFLYLGSILVDEYGMEEGCRQGLLDMLQALCIPTFQLLEQ 738

Query: 782 --GPRDHPDIVDSFMQLLAQALKRKPDLFLCERLDVKAVFQCAVLALKFPEAPTVKASCG 839
             G ++HPD VD   +L  + ++R P   L  ++ V  + Q A+ +          +   
Sbjct: 739 QNGLQNHPDTVDDLFRLATRFIQRSPVTLLRSQV-VIPILQWAIASTTLDHRDANCSVMR 797

Query: 840 FFTELLPRCG-----------EVESVGKVVQEDGRMLLIAVLEAIGGQASRSLMDCFADI 888
           F  +L+   G             E +G+V+ + G+ L+  +L           +   A++
Sbjct: 798 FLRDLI-HTGVANDHEEDFELRKELIGQVMNQLGQQLVSQLLHTCCFCLPPYTLPDVAEV 856

Query: 889 LFALNKHCFSLLSMWIKEALQPPGFP------SARLSPEQKDTFSQQILRERVNKRRVKE 942
           L+ + +        W++ +L+  G P      +  ++ +Q   F +Q+      K +V  
Sbjct: 857 LWEIMQVDRPTFCRWLENSLK--GLPKETTVGAVTVTHKQLTDFHKQVTSAEECK-QVCW 913

Query: 943 MVKEFTLLCR 952
            +++FT L R
Sbjct: 914 ALRDFTRLFR 923


>gi|4507943 exportin 1 [Homo sapiens]
          Length = 1071

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 125/700 (17%), Positives = 275/700 (39%), Gaps = 85/700 (12%)

Query: 11  AGAGAAPALDFT----VENVEKALHQLYYDPNIENKNLAQKWLMQAQVSPQAWHFSWQLL 66
           A   A   LDF+    +  ++  ++ LY+    + + +AQ+ L   +  P AW     +L
Sbjct: 9   ADHAARQLLDFSQKLDINLLDNVVNCLYHGEGAQQR-MAQEVLTHLKEHPDAWTRVDTIL 67

Query: 67  QPDKVPEIQYFGASALHIKISRYWSDIPTDQYESLKAQLFTQITRFASG------SKIVL 120
           +  +    +Y+G   L   I   W  +P +Q E +K  +   I + +S        K+ +
Sbjct: 68  EFSQNMNTKYYGLQILENVIKTRWKILPRNQCEGIKKYVVGLIIKTSSDPTCVEKEKVYI 127

Query: 121 TRLCVALASLALSMMPDAWPCAVADMVRLFQAEDSPVDGQGRCLALLELLTVLPEEFQTS 180
            +L + L  +     P  WP  ++D+V   +  +S        + +L+LL+    +F + 
Sbjct: 128 GKLNMILVQILKQEWPKHWPTFISDIVGASRTSESLCQNN---MVILKLLSEEVFDFSSG 184

Query: 181 RLPQYRKGLVRTSLAVECGAVFPLLEQLLQQPSSPSCVRQ--KVLKCFSSWVQLEVPLQD 238
           ++ Q +   ++ S+  E   +F L + +++   +   V    + L  F +W+ L    + 
Sbjct: 185 QITQVKSKHLKDSMCNEFSQIFQLCQFVMENSQNAPLVHATLETLLRFLNWIPLGYIFE- 243

Query: 239 CEALIQAAFAALQDSELFDSSVEAIVNAISQPDAQRYVNTLLKLIPL-------VLGLQE 291
              LI        +  +F +     +  I+     +Y    + L  L       +L L  
Sbjct: 244 -TKLISTLIYKFLNVPMFRNVSLKCLTEIAGVSVSQYEEQFVTLFTLTMMQLKQMLPLNT 302

Query: 292 QLRQAVQNGDMETSHGICRIAVALG---ENHSRALLDQVEHWQSFLALVNMIMFCTGIPG 348
            +R A  NG  +  + I  +++ L    + H + +  ++   ++ +  ++ ++  +    
Sbjct: 303 NIRLAYSNGKDDEQNFIQNLSLFLCTFLKEHDQLIEKRLNLRETLMEALHYMLLVS---- 358

Query: 349 HYPVNET-TSSLTLTFWYTLQDDIL---SFEAEKQAVY-----------QQVYRPVYFQL 393
              V ET    + L +W  L  ++     F      +            +Q+Y P+ F++
Sbjct: 359 --EVEETEIFKICLEYWNHLAAELYRESPFSTSASPLLSGSQHFDVPPRRQLYLPMLFKV 416

Query: 394 VDVLLHKAQFPSDEEYGFWSSDEKEQFRIYRVD---------ISDTLMYVYEMLGAELLS 444
              LL  ++    EE     +D+ E  R +  D         + +TL+Y+  +   +   
Sbjct: 417 --RLLMVSRMAKPEEVLVVENDQGEVVREFMKDTDSINLYKNMRETLVYLTHLDYVDTER 474

Query: 445 NLYDKLGRLLTSSEEPYSWQHTEALLYGFQSIAETIDVN-----YSDVVPGLIGLI--PR 497
            + +KL   +  +E  +SW++   L +   SI+  +           V+  L+GL    R
Sbjct: 475 IMTEKLHNQVNGTE--WSWKNLNTLCWAIGSISGAMHEEDEKRFLVTVIKDLLGLCEQKR 532

Query: 498 ISISNVQLADTVMFTIGALSEWLADHPVMINSVLPLVLHALGNPELSVSSVS--TLKKIC 555
              +   +A  +M+ +G    +L  H   + +V+  +   +      V  ++  T  KI 
Sbjct: 533 GKDNKAIIASNIMYIVGQYPRFLRAHWKFLKTVVNKLFEFMHETHDGVQDMACDTFIKIA 592

Query: 556 RECKYDLPPYAANIVAVSQDVLMKQIH------KTSQCMWLMQALGFLLSALQVEEILKN 609
           ++C+          V    D ++  I+      +  Q     +A+G+++ A   + + ++
Sbjct: 593 QKCRRHFVQVQVGEVMPFIDEILNNINTIICDLQPQQVHTFYEAVGYMIGAQTDQTVQEH 652

Query: 610 L--------HSLISPYIQQLEKLAEEIPNPSNKLAIVHIL 641
           L        + +    IQQ  K  + + +P     +  IL
Sbjct: 653 LIEKYMLLPNQVWDSIIQQATKNVDILKDPETVKQLGSIL 692


>gi|53759103 importin 8 [Homo sapiens]
          Length = 1037

 Score = 39.7 bits (91), Expect = 0.014
 Identities = 43/176 (24%), Positives = 73/176 (41%), Gaps = 28/176 (15%)

Query: 79  ASALHIK--ISRYWSD---------IPTDQYESLKAQLFTQITR-FASGSKIVLTRLCVA 126
           A+A+++K  +++YW D          P + +E+ + Q+   I         +V  +L + 
Sbjct: 55  AAAIYLKNMVTQYWPDREPPPGEAIFPFNIHENDRQQIRDNIVEGIIRSPDLVRVQLTMC 114

Query: 127 LASLALSMMPDAWPCAVADMVRLFQAEDSPVDGQGRCLALLELLTVLPEEFQTSRLPQYR 186
           L ++     P  WP  V D +  +    S     G  L L +L+             +Y+
Sbjct: 115 LRAIIKHDFPGHWP-GVVDKIDYYLQSQSSASWLGSLLCLYQLVKTY----------EYK 163

Query: 187 KGLVRTSLAVECGAVFPLLEQ----LLQQPSSPSCVRQK-VLKCFSSWVQLEVPLQ 237
           K   R  L +      P ++Q    LL   S  S + QK +LK F + VQ  +PLQ
Sbjct: 164 KAEEREPLIIAMQIFLPRIQQQIVQLLPDSSYYSVLLQKQILKIFYALVQYALPLQ 219


>gi|62460637 importin 4 [Homo sapiens]
          Length = 1081

 Score = 38.1 bits (87), Expect = 0.040
 Identities = 42/159 (26%), Positives = 66/159 (41%), Gaps = 16/159 (10%)

Query: 26  VEKALHQLYYDPNIENKNLAQKWLMQAQVSPQAWHFSWQLLQPDKVPEIQYFGASALHIK 85
           +E+ L +L   P+ E    A + L     +P A      LL     P+I+ F A     +
Sbjct: 6   LEQLLRELLL-PDTERIRRATEQLQIVLRAPAALPALCDLLASAADPQIRQFAAVLTRRR 64

Query: 86  ISRYWSDIPTDQYESLKAQLFTQITRFASGSKIVLTRLCVALASLALSMM------PDAW 139
           ++  W  +  +Q ESLK+ + T + R         T  CV+L+   LS         +AW
Sbjct: 65  LNTRWRRLAAEQRESLKSLILTALQR--------ETEHCVSLSLAQLSATIFRKEGLEAW 116

Query: 140 PCAVADMVRLFQAEDSPVDGQGRCLALLELLTVLPEEFQ 178
           P  +  +     +  SP    G  L L  ++T  PE FQ
Sbjct: 117 PQLLQLLQHSTHSPHSPEREMG-LLLLSVVVTSRPEAFQ 154


>gi|8051636 tRNA exportin [Homo sapiens]
          Length = 962

 Score = 36.6 bits (83), Expect = 0.12
 Identities = 50/270 (18%), Positives = 106/270 (39%), Gaps = 14/270 (5%)

Query: 27  EKALHQLYYDPNIENKNLAQKWLMQAQVSPQAWHFSWQLLQPDKVPE--IQYFGASALHI 84
           E+AL  L  + + + +  A  +  Q ++SP AW    + L      +  +++F    L  
Sbjct: 3   EQALLGLNPNADSDFRQRALAYFEQLKISPDAWQVCAEALAQRTYSDDHVKFFCFQVLEH 62

Query: 85  KISRYWSDIPTDQY----ESLKAQLFTQITRFASGSKIVLTRLCVALASLALSMMPDAWP 140
           ++   +S++ T Q     E+L + L  Q+         +  +     A L ++     WP
Sbjct: 63  QVKYKYSELTTVQQQLIRETLISWLQAQMLNPQPEKTFIRNKAAQVFALLFVTEYLTKWP 122

Query: 141 CAVADMVRLFQAEDSPVDGQGRCLALLELLTVLPEEFQTSRLPQYRKGLVRTSLAVEC-- 198
               D++ +       VD   R L  ++   V  +   TS   + R  L++ ++  +C  
Sbjct: 123 KFFFDILSVVDLNPRGVDLYLRILMAIDSELVDRDVVHTSEEAR-RNTLIKDTMREQCIP 181

Query: 199 ---GAVFPLLEQLLQQPSSPSCVRQKVLKCFSSWVQLEVPLQD--CEALIQAAFAALQDS 253
               + + +L+      S  +C   +V+  + SW+ L +   D     L+      +   
Sbjct: 182 NLVESWYQILQNYQFTNSEVTCQCLEVVGAYVSWIDLSLIANDRFINMLLGHMSIEVLRE 241

Query: 254 ELFDSSVEAIVNAISQPDAQRYVNTLLKLI 283
           E  D   E +   +   D  + V +L +++
Sbjct: 242 EACDCLFEVVNKGMDPVDKMKLVESLCQVL 271


>gi|148886661 exportin 4 [Homo sapiens]
          Length = 1151

 Score = 33.1 bits (74), Expect = 1.3
 Identities = 44/227 (19%), Positives = 89/227 (39%), Gaps = 5/227 (2%)

Query: 11  AGAGAAPALDFTVENVEKALHQLYYDPNIENKNLAQKWLMQAQVSPQAWHFSWQLLQPDK 70
           A A   P +   +EN  K L       N E +  A+   +  + S   +     +L+  K
Sbjct: 3   AAALGPPEVIAQLENAAKVLMAPPSMVNNEQRQHAEHIFLSFRKSKSPFAVCKHILETSK 62

Query: 71  VPEIQYFGASALHIKISRYWSDIPTDQYESLKAQLFTQITRFASGSKIVLTRLCVALASL 130
           V  + +  A+A+   + R W  +     ESL+  L T + +  +  K V  ++ +A+A +
Sbjct: 63  VDYVLFQAATAIMEAVVREWILLEKGSIESLRTFLLTYVLQRPNLQKYVREQILLAVAVI 122

Query: 131 A-LSMMPDAWPC-AVADMVRLFQAEDSPVDGQGRCLALLELLTVLPEEFQTSRL---PQY 185
                +  +  C ++   V    +  +P      C  L  LL+      +TS +    ++
Sbjct: 123 VKRGSLDKSIDCKSIFHEVSQLISSGNPTVQTLACSILTALLSEFSSSSKTSNIGLSMEF 182

Query: 186 RKGLVRTSLAVECGAVFPLLEQLLQQPSSPSCVRQKVLKCFSSWVQL 232
                R     +   +F L  ++LQ+ S    +  ++   F  ++ L
Sbjct: 183 HGNCKRVFQEEDLRQIFMLTVEVLQEFSRRENLNAQMSSVFQRYLAL 229


>gi|51558724 ADAM metallopeptidase with thrombospondin type 1 motif,
            12 preproprotein [Homo sapiens]
          Length = 1594

 Score = 31.2 bits (69), Expect = 4.9
 Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 1/56 (1%)

Query: 785  DHPDIVDSFMQLLAQALKRKPDLFLCERLDVKAVFQCAVLALKFPEAPTVKASCGF 840
            DH      F +   QA K+  DL LC +  + A F   + A+K    PTV+A C F
Sbjct: 1515 DHKPRPPEFKKCNQQACKKSADL-LCTKDKLSASFCQTLKAMKKCSVPTVRAECCF 1569


>gi|239753475 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 721

 Score = 30.8 bits (68), Expect = 6.4
 Identities = 20/66 (30%), Positives = 35/66 (53%), Gaps = 7/66 (10%)

Query: 279 LLKLIPLVLGLQEQLRQAVQNGDMETSHGICRIAVALGENHSRALLDQVEHWQSFLALVN 338
           LL ++ L+LGL       +Q  D++  H +C +  AL +   RAL + VE  +  L + +
Sbjct: 644 LLDVLDLILGL-------LQVDDLDGHHLLCVVIDALVDLPKRALANAVELGEELLRVHS 696

Query: 339 MIMFCT 344
            ++F T
Sbjct: 697 RVLFLT 702


>gi|239748044 PREDICTED: hypothetical protein XP_002346500 [Homo
           sapiens]
          Length = 721

 Score = 30.8 bits (68), Expect = 6.4
 Identities = 20/66 (30%), Positives = 35/66 (53%), Gaps = 7/66 (10%)

Query: 279 LLKLIPLVLGLQEQLRQAVQNGDMETSHGICRIAVALGENHSRALLDQVEHWQSFLALVN 338
           LL ++ L+LGL       +Q  D++  H +C +  AL +   RAL + VE  +  L + +
Sbjct: 644 LLDVLDLILGL-------LQVDDLDGHHLLCVVIDALVDLPKRALANAVELGEELLRVHS 696

Query: 339 MIMFCT 344
            ++F T
Sbjct: 697 RVLFLT 702


>gi|239741935 PREDICTED: hypothetical protein XP_002342357 [Homo
           sapiens]
          Length = 721

 Score = 30.8 bits (68), Expect = 6.4
 Identities = 20/66 (30%), Positives = 35/66 (53%), Gaps = 7/66 (10%)

Query: 279 LLKLIPLVLGLQEQLRQAVQNGDMETSHGICRIAVALGENHSRALLDQVEHWQSFLALVN 338
           LL ++ L+LGL       +Q  D++  H +C +  AL +   RAL + VE  +  L + +
Sbjct: 644 LLDVLDLILGL-------LQVDDLDGHHLLCVVIDALVDLPKRALANAVELGEELLRVHS 696

Query: 339 MIMFCT 344
            ++F T
Sbjct: 697 RVLFLT 702


>gi|11386135 branched chain keto acid dehydrogenase E1, alpha
           polypeptide [Homo sapiens]
          Length = 445

 Score = 30.4 bits (67), Expect = 8.3
 Identities = 18/79 (22%), Positives = 38/79 (48%), Gaps = 1/79 (1%)

Query: 404 PSDEEYGFWSSDEKEQFRIYRVDISDTLMYVY-EMLGAELLSNLYDKLGRLLTSSEEPYS 462
           P  ++  F S D+K QF     +  D L ++   ++    +  + D+ G+++  SE+P+ 
Sbjct: 38  PPRQQQQFSSLDDKPQFPGASAEFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHL 97

Query: 463 WQHTEALLYGFQSIAETID 481
            +     LY   ++  T+D
Sbjct: 98  PKEKVLKLYKSMTLLNTMD 116


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,595,387
Number of Sequences: 37866
Number of extensions: 1519354
Number of successful extensions: 3917
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 3905
Number of HSP's gapped (non-prelim): 14
length of query: 963
length of database: 18,247,518
effective HSP length: 112
effective length of query: 851
effective length of database: 14,006,526
effective search space: 11919553626
effective search space used: 11919553626
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.