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Search of human proteins with 224809419
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224809419 Homer, neuronal immediate early gene, 3 isoform 3
[Homo sapiens]
(325 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224809419 Homer, neuronal immediate early gene, 3 isoform 3 [... 629 e-180
gi|224809414 Homer, neuronal immediate early gene, 3 isoform 1 [... 611 e-175
gi|224809408 Homer, neuronal immediate early gene, 3 isoform 1 [... 611 e-175
gi|224809410 Homer, neuronal immediate early gene, 3 isoform 2 [... 600 e-172
gi|4759198 homer 1 [Homo sapiens] 278 6e-75
gi|46249349 homer 2 isoform 1 [Homo sapiens] 253 2e-67
gi|46249351 homer 2 isoform 2 [Homo sapiens] 249 2e-66
gi|110349794 homer 2 isoform 3 [Homo sapiens] 201 7e-52
gi|110349797 homer 2 isoform 4 [Homo sapiens] 201 1e-51
gi|56549694 enabled homolog isoform a [Homo sapiens] 79 7e-15
gi|39930375 enabled homolog isoform b [Homo sapiens] 79 7e-15
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 56 5e-08
gi|126723390 ankyrin repeat domain 24 [Homo sapiens] 55 8e-08
gi|7706687 Enah/Vasp-like [Homo sapiens] 54 1e-07
gi|156766068 CDC42 binding protein kinase gamma (DMPK-like) [Hom... 54 2e-07
gi|157738667 FYVE and coiled-coil domain containing 1 [Homo sapi... 54 2e-07
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 53 4e-07
gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens] 52 6e-07
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 52 6e-07
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 52 9e-07
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 52 9e-07
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 52 9e-07
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 52 9e-07
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 52 9e-07
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 52 9e-07
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 52 9e-07
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 52 9e-07
gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 52 9e-07
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 51 1e-06
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 50 3e-06
>gi|224809419 Homer, neuronal immediate early gene, 3 isoform 3
[Homo sapiens]
Length = 325
Score = 629 bits (1622), Expect = e-180
Identities = 325/325 (100%), Positives = 325/325 (100%)
Query: 1 MSTAREQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAII 60
MSTAREQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAII
Sbjct: 1 MSTAREQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAII 60
Query: 61 NSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQVPPSPLVSANGPGEEKLFR 120
NSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQVPPSPLVSANGPGEEKLFR
Sbjct: 61 NSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQVPPSPLVSANGPGEEKLFR 120
Query: 121 SQSADAPGPTERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQ 180
SQSADAPGPTERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQ
Sbjct: 121 SQSADAPGPTERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQ 180
Query: 181 LEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKS 240
LEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKS
Sbjct: 181 LEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKS 240
Query: 241 QTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARAERERARAEVGRAA 300
QTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARAERERARAEVGRAA
Sbjct: 241 QTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARAERERARAEVGRAA 300
Query: 301 QLLDVSLFELSELREGLARLAEAAP 325
QLLDVSLFELSELREGLARLAEAAP
Sbjct: 301 QLLDVSLFELSELREGLARLAEAAP 325
>gi|224809414 Homer, neuronal immediate early gene, 3 isoform 1
[Homo sapiens]
Length = 361
Score = 611 bits (1575), Expect = e-175
Identities = 325/361 (90%), Positives = 325/361 (90%), Gaps = 36/361 (9%)
Query: 1 MSTAREQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAII 60
MSTAREQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAII
Sbjct: 1 MSTAREQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAII 60
Query: 61 NSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQ------------------- 101
NSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQ
Sbjct: 61 NSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQFAEKFQEVKEAARLAREKS 120
Query: 102 -----------------VPPSPLVSANGPGEEKLFRSQSADAPGPTERERLKKMLSEGSV 144
VPPSPLVSANGPGEEKLFRSQSADAPGPTERERLKKMLSEGSV
Sbjct: 121 QDGGELTSPALGLASHQVPPSPLVSANGPGEEKLFRSQSADAPGPTERERLKKMLSEGSV 180
Query: 145 GEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAAS 204
GEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAAS
Sbjct: 181 GEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAAS 240
Query: 205 EVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDL 264
EVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDL
Sbjct: 241 EVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDL 300
Query: 265 ETRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEAA 324
ETRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEAA
Sbjct: 301 ETRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEAA 360
Query: 325 P 325
P
Sbjct: 361 P 361
>gi|224809408 Homer, neuronal immediate early gene, 3 isoform 1
[Homo sapiens]
Length = 361
Score = 611 bits (1575), Expect = e-175
Identities = 325/361 (90%), Positives = 325/361 (90%), Gaps = 36/361 (9%)
Query: 1 MSTAREQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAII 60
MSTAREQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAII
Sbjct: 1 MSTAREQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAII 60
Query: 61 NSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQ------------------- 101
NSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQ
Sbjct: 61 NSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQFAEKFQEVKEAARLAREKS 120
Query: 102 -----------------VPPSPLVSANGPGEEKLFRSQSADAPGPTERERLKKMLSEGSV 144
VPPSPLVSANGPGEEKLFRSQSADAPGPTERERLKKMLSEGSV
Sbjct: 121 QDGGELTSPALGLASHQVPPSPLVSANGPGEEKLFRSQSADAPGPTERERLKKMLSEGSV 180
Query: 145 GEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAAS 204
GEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAAS
Sbjct: 181 GEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAAS 240
Query: 205 EVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDL 264
EVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDL
Sbjct: 241 EVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDL 300
Query: 265 ETRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEAA 324
ETRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEAA
Sbjct: 301 ETRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEAA 360
Query: 325 P 325
P
Sbjct: 361 P 361
>gi|224809410 Homer, neuronal immediate early gene, 3 isoform 2
[Homo sapiens]
Length = 358
Score = 600 bits (1546), Expect = e-172
Identities = 322/361 (89%), Positives = 322/361 (89%), Gaps = 39/361 (10%)
Query: 1 MSTAREQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAII 60
MSTAREQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAII
Sbjct: 1 MSTAREQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAII 60
Query: 61 NSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQ------------------- 101
NSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQ
Sbjct: 61 NSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQFAEKFQEVKEAARLAREKS 120
Query: 102 -----------------VPPSPLVSANGPGEEKLFRSQSADAPGPTERERLKKMLSEGSV 144
VPPSPLVSANGPGEEKLFRSQSADAPGPTERERLKKMLSEGSV
Sbjct: 121 QDGGELTSPALGLASHQVPPSPLVSANGPGEEKLFRSQSADAPGPTERERLKKMLSEGSV 180
Query: 145 GEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAAS 204
GEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAAS
Sbjct: 181 GEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAAS 240
Query: 205 EVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDL 264
EVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQ
Sbjct: 241 EVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQ-- 298
Query: 265 ETRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEAA 324
TRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEAA
Sbjct: 299 -TRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEAA 357
Query: 325 P 325
P
Sbjct: 358 P 358
>gi|4759198 homer 1 [Homo sapiens]
Length = 354
Score = 278 bits (710), Expect = 6e-75
Identities = 165/359 (45%), Positives = 214/359 (59%), Gaps = 47/359 (13%)
Query: 6 EQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAIINSTVT 65
EQPIFSTRAHVFQIDP TK+NW+P KHA+TVSYFYD+TRNVYRIIS+ G+KAIINST+T
Sbjct: 3 EQPIFSTRAHVFQIDPNTKKNWVPTSKHAVTVSYFYDSTRNVYRIISLDGSKAIINSTIT 62
Query: 66 PNMTFTKTSQKFGQWADSRANTVYGLGFASEQH--------------------------- 98
PNMTFTKTSQKFGQWADSRANTVYGLGF+SE H
Sbjct: 63 PNMTFTKTSQKFGQWADSRANTVYGLGFSSEHHLSKFAEKFQEFKEAARLAKEKSQEKME 122
Query: 99 LTQVP---------PSPLV--SANGPGEEKL--FRSQSADAPGPTERERLKKMLSEGSVG 145
LT P SPL S NG +E+ S PT+ S S
Sbjct: 123 LTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRAEPTQN---ALPFSHSSAI 179
Query: 146 EVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASE 205
WEAE L+ +N KL AL E+ A QW+QQL A + EAERL +RV ELE ++
Sbjct: 180 SKHWEAELATLKGNNAKLTAALLESTANVKQWKQQLAAYQEEAERLHKRVTELECVSSQA 239
Query: 206 VTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLE 265
K L Q++++LE ++ K++EI+ LK + RE E +R+ QK+Q++E
Sbjct: 240 NAVHTHKTEL--NQTIQELEETLKLKEEEIERLKQEIDNARELQE--QRDSLTQKLQEVE 295
Query: 266 TRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEAA 324
RN +LE QL +E+ LE+++ E+E R + ++LD +FEL+ELR+ LA+L E +
Sbjct: 296 IRNKDLEGQLSDLEQRLEKSQNEQEAFRNNLKTLLEILDGKIFELTELRDNLAKLLECS 354
>gi|46249349 homer 2 isoform 1 [Homo sapiens]
Length = 343
Score = 253 bits (646), Expect = 2e-67
Identities = 143/341 (41%), Positives = 208/341 (60%), Gaps = 30/341 (8%)
Query: 6 EQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAIINSTVT 65
EQPIF+TRAHVFQIDP TK+NW+PA K A+TVSYFYD TRN YRIIS+ GAK IINST+T
Sbjct: 3 EQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINSTIT 62
Query: 66 PNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQVPP--------------------- 104
PNMTFTKTSQKFGQWADSRANTV+GLGF+SEQ LT+
Sbjct: 63 PNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEKIE 122
Query: 105 -----SPLVSANGPGEEKLFRSQSADAPGPTERERLKKMLSEGSVGEVQWEAEFFALQDS 159
S S NG +EK + A+ +E ++LK L++ + +WE E L++S
Sbjct: 123 TSSNHSQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQSAANVKKWEIELQTLRES 182
Query: 160 NNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQ 219
N +L AL+E+ A+ QW++Q R E +RLR ++ ELE Q SE+ EK +
Sbjct: 183 NARLTTALQESAASVEQWKRQFSICRDENDRLRNKIDELEEQ-CSEINREKEK-NTQLKR 240
Query: 220 SLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAME 279
+E+LEA ++ K+ E++ L+ Q+ + + +E E +K++ E N LE ++R+++
Sbjct: 241 RIEELEAELREKETELKDLRKQSEIIPQLM--SECEYVSEKLEAAERDNQNLEDKVRSLK 298
Query: 280 RSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARL 320
+EE++ + + E+ ++LD + +L + R GL++L
Sbjct: 299 TDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKL 339
>gi|46249351 homer 2 isoform 2 [Homo sapiens]
Length = 354
Score = 249 bits (636), Expect = 2e-66
Identities = 144/352 (40%), Positives = 210/352 (59%), Gaps = 41/352 (11%)
Query: 6 EQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAIINSTVT 65
EQPIF+TRAHVFQIDP TK+NW+PA K A+TVSYFYD TRN YRIIS+ GAK IINST+T
Sbjct: 3 EQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINSTIT 62
Query: 66 PNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLT------------------------- 100
PNMTFTKTSQKFGQWADSRANTV+GLGF+SEQ LT
Sbjct: 63 PNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEKIE 122
Query: 101 -----------QVPPSPLVSA-NGPGEEKLFRSQSADAPGPTERERLKKMLSEGSVGEVQ 148
+ P S S+ NG +EK + A+ +E ++LK L++ + +
Sbjct: 123 TSSNHSQESGRETPSSTQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQSAANVKK 182
Query: 149 WEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTP 208
WE E L++SN +L AL+E+ A+ QW++Q R E +RLR ++ ELE Q SE+
Sbjct: 183 WEIELQTLRESNARLTTALQESAASVEQWKRQFSICRDENDRLRNKIDELEEQ-CSEINR 241
Query: 209 TGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRN 268
EK + +E+LEA ++ K+ E++ L+ Q+ + + +E E +K++ E N
Sbjct: 242 EKEK-NTQLKRRIEELEAELREKETELKDLRKQSEIIPQLM--SECEYVSEKLEAAERDN 298
Query: 269 AELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARL 320
LE ++R+++ +EE++ + + E+ ++LD + +L + R GL++L
Sbjct: 299 QNLEDKVRSLKTDIEESKYRQRHLKVELKSFLEVLDGKIDDLHDFRRGLSKL 350
>gi|110349794 homer 2 isoform 3 [Homo sapiens]
Length = 288
Score = 201 bits (511), Expect = 7e-52
Identities = 125/321 (38%), Positives = 178/321 (55%), Gaps = 45/321 (14%)
Query: 6 EQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAIINSTVT 65
EQPIF+TRAHVFQIDP TK+NW+PA K A+TVSYFYD TRN YRIIS+ GAK IINST+T
Sbjct: 3 EQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINSTIT 62
Query: 66 PNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLT------QVPPSPLVSANGPGEEKLF 119
PNMTFTKTSQKFGQWADSRANTV+GLGF+SEQ LT Q A +EK+
Sbjct: 63 PNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEKIE 122
Query: 120 RSQSADAPGPTERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQ 179
S + +K G L+ N+KL AL + +AA +
Sbjct: 123 TSSNHSQASSVNGTDDEKASHAGPANT--------HLKSENDKLKIALTQ---SAANVKN 171
Query: 180 QLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLK 239
++ ++ + +L++R+ ELEA+ + T + ++ + + I L
Sbjct: 172 EINREKEKNTQLKRRIEELEAELREKETELKD----------------LRKQSEIIPQLM 215
Query: 240 SQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARAERERARAEVGRA 299
S+ E LEAAER+ N LE ++R+++ +EE++ + + E+
Sbjct: 216 SECEYVSEKLEAAERD------------NQNLEDKVRSLKTDIEESKYRQRHLKVELKSF 263
Query: 300 AQLLDVSLFELSELREGLARL 320
++LD + +L + R GL++L
Sbjct: 264 LEVLDGKIDDLHDFRRGLSKL 284
>gi|110349797 homer 2 isoform 4 [Homo sapiens]
Length = 299
Score = 201 bits (510), Expect = 1e-51
Identities = 126/324 (38%), Positives = 181/324 (55%), Gaps = 40/324 (12%)
Query: 6 EQPIFSTRAHVFQIDPATKRNWIPAGKHALTVSYFYDATRNVYRIISIGGAKAIINSTVT 65
EQPIF+TRAHVFQIDP TK+NW+PA K A+TVSYFYD TRN YRIIS+ GAK IINST+T
Sbjct: 3 EQPIFTTRAHVFQIDPNTKKNWMPASKQAVTVSYFYDVTRNSYRIISVDGAKVIINSTIT 62
Query: 66 PNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLT------QVPPSPLVSANGPGEEKLF 119
PNMTFTKTSQKFGQWADSRANTV+GLGF+SEQ LT Q A +EK+
Sbjct: 63 PNMTFTKTSQKFGQWADSRANTVFGLGFSSEQQLTKFAEKFQEVKEAAKIAKDKTQEKIE 122
Query: 120 RSQSADAPGPTERERLKKMLSEGSVGEVQWEAEFFA---LQDSNNKLAGALREANAAAAQ 176
S + E + S + + A L+ N+KL AL + +AA
Sbjct: 123 TSSNHSQESGRETPSSTQASSVNGTDDEKASHAGPANTHLKSENDKLKIALTQ---SAAN 179
Query: 177 WRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQ 236
+ ++ ++ + +L++R+ ELEA+ + T + ++ + + I
Sbjct: 180 VKNEINREKEKNTQLKRRIEELEAELREKETELKD----------------LRKQSEIIP 223
Query: 237 TLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARAERERARAEV 296
L S+ E LEAAER+ N LE ++R+++ +EE++ + + E+
Sbjct: 224 QLMSECEYVSEKLEAAERD------------NQNLEDKVRSLKTDIEESKYRQRHLKVEL 271
Query: 297 GRAAQLLDVSLFELSELREGLARL 320
++LD + +L + R GL++L
Sbjct: 272 KSFLEVLDGKIDDLHDFRRGLSKL 295
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 78.6 bits (192), Expect = 7e-15
Identities = 81/286 (28%), Positives = 120/286 (41%), Gaps = 40/286 (13%)
Query: 6 EQPIFSTRAHVFQIDPATKRNWIPAGKHA--LTVSYFYDATRNVYRIIS--IGGAKAIIN 61
EQ I RA V D A K+ W+PAG V ++ N +R++ I + +IN
Sbjct: 3 EQSICQARAAVMVYDDANKK-WVPAGGSTGFSRVHIYHHTGNNTFRVVGRKIQDHQVVIN 61
Query: 62 STVTPNMTFTKTSQKFGQWADSRANTVYGLGFASEQ----------HLTQVPPSPLVSAN 111
+ + + + +Q F QW D+R VYGL F S++ H +V S
Sbjct: 62 CAIPKGLKYNQATQTFHQWRDAR--QVYGLNFGSKEDANVFASAMMHALEVLNSQETGPT 119
Query: 112 GPGEEKLFRSQSADAPGPTERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREAN 171
P + +Q + P E E ++ L E + Q E E L+ RE
Sbjct: 120 LPRQNSQLPAQVQNGPSQEELEIQRRQLQE---QQRQKELERERLE----------RERM 166
Query: 172 AAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLEQLEALVQTK 231
R++LE +R E ERL Q E E Q +E L + + LE+ E L
Sbjct: 167 ERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERL---- 222
Query: 232 DQEIQTLKSQTGGPREALEAAEREETQQKVQD-LETRNAELEHQLR 276
D+E Q + RE LE ERE +++ Q+ LE E E + R
Sbjct: 223 DRERQERQE-----RERLERLERERQERERQEQLEREQLEWERERR 263
Score = 30.8 bits (68), Expect = 1.7
Identities = 23/58 (39%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Query: 241 QTGGPREALEAAERE-ETQQKVQDLETRNAELEHQLRA-MERS-LEEARAERERARAE 295
Q G +E LE R+ + QQ+ ++LE E E R +ER LE R ERER E
Sbjct: 132 QNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQE 189
Score = 30.0 bits (66), Expect = 2.9
Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 22/129 (17%)
Query: 165 GALREANAAAAQWRQQLEAQRAE--AERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLE 222
G+ +AN A+ LE ++ L ++ ++L AQ + G S E
Sbjct: 92 GSKEDANVFASAMMHALEVLNSQETGPTLPRQNSQLPAQVQN-------------GPSQE 138
Query: 223 QLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSL 282
+LE + +++Q + Q RE LE E + + + LE E E R + L
Sbjct: 139 ELEI----QRRQLQEQQRQKELERERLERERMERERLERERLERERLERE---RLEQEQL 191
Query: 283 EEARAERER 291
E R ERER
Sbjct: 192 ERERQERER 200
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 78.6 bits (192), Expect = 7e-15
Identities = 81/286 (28%), Positives = 120/286 (41%), Gaps = 40/286 (13%)
Query: 6 EQPIFSTRAHVFQIDPATKRNWIPAGKHA--LTVSYFYDATRNVYRIIS--IGGAKAIIN 61
EQ I RA V D A K+ W+PAG V ++ N +R++ I + +IN
Sbjct: 3 EQSICQARAAVMVYDDANKK-WVPAGGSTGFSRVHIYHHTGNNTFRVVGRKIQDHQVVIN 61
Query: 62 STVTPNMTFTKTSQKFGQWADSRANTVYGLGFASEQ----------HLTQVPPSPLVSAN 111
+ + + + +Q F QW D+R VYGL F S++ H +V S
Sbjct: 62 CAIPKGLKYNQATQTFHQWRDAR--QVYGLNFGSKEDANVFASAMMHALEVLNSQETGPT 119
Query: 112 GPGEEKLFRSQSADAPGPTERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREAN 171
P + +Q + P E E ++ L E + Q E E L+ RE
Sbjct: 120 LPRQNSQLPAQVQNGPSQEELEIQRRQLQE---QQRQKELERERLE----------RERM 166
Query: 172 AAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLEQLEALVQTK 231
R++LE +R E ERL Q E E Q +E L + + LE+ E L
Sbjct: 167 ERERLERERLERERLERERLEQEQLERERQERERQERLERQERLERQERLERQERL---- 222
Query: 232 DQEIQTLKSQTGGPREALEAAEREETQQKVQD-LETRNAELEHQLR 276
D+E Q + RE LE ERE +++ Q+ LE E E + R
Sbjct: 223 DRERQERQE-----RERLERLERERQERERQEQLEREQLEWERERR 263
Score = 30.8 bits (68), Expect = 1.7
Identities = 23/58 (39%), Positives = 30/58 (51%), Gaps = 3/58 (5%)
Query: 241 QTGGPREALEAAERE-ETQQKVQDLETRNAELEHQLRA-MERS-LEEARAERERARAE 295
Q G +E LE R+ + QQ+ ++LE E E R +ER LE R ERER E
Sbjct: 132 QNGPSQEELEIQRRQLQEQQRQKELERERLERERMERERLERERLERERLERERLEQE 189
Score = 30.0 bits (66), Expect = 2.9
Identities = 34/129 (26%), Positives = 54/129 (41%), Gaps = 22/129 (17%)
Query: 165 GALREANAAAAQWRQQLEAQRAE--AERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLE 222
G+ +AN A+ LE ++ L ++ ++L AQ + G S E
Sbjct: 92 GSKEDANVFASAMMHALEVLNSQETGPTLPRQNSQLPAQVQN-------------GPSQE 138
Query: 223 QLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSL 282
+LE + +++Q + Q RE LE E + + + LE E E R + L
Sbjct: 139 ELEI----QRRQLQEQQRQKELERERLERERMERERLERERLERERLERE---RLEQEQL 191
Query: 283 EEARAERER 291
E R ERER
Sbjct: 192 ERERQERER 200
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 55.8 bits (133), Expect = 5e-08
Identities = 54/212 (25%), Positives = 92/212 (43%), Gaps = 45/212 (21%)
Query: 115 EEKLFRSQSADAPGPTERERLKKMLSEGSVGEVQWEAEFFALQDSNNK----------LA 164
EE+L R Q + E+ +K+ + E Q +AE ++ + L
Sbjct: 344 EEELLRLQQL------QEEKERKLQELELLQEAQRQAERLLQEEEERRRSQHRELQQALE 397
Query: 165 GALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAAS-------EVTPTGEKEGLGQ 217
G LREA A A + ++E + EA R RQR+ ELE EV ++E +
Sbjct: 398 GQLREAEQARASMQAEMELKEEEAARQRQRIKELEEMQQRLQEALQLEVKARRDEESVRI 457
Query: 218 GQSL------EQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAEL 271
Q+ E+L+ L+Q K+++ + + E QQ+ ++L+ A+
Sbjct: 458 AQTRLLEEEEEKLKQLMQLKEEQERYI----------------ERAQQEKEELQQEMAQQ 501
Query: 272 EHQLRAMERSLEEARAERERARAEVGRAAQLL 303
L+ ++ LEE R R+RA +V A + L
Sbjct: 502 SRSLQQAQQQLEEVRQNRQRADEDVEAAQRKL 533
>gi|126723390 ankyrin repeat domain 24 [Homo sapiens]
Length = 1146
Score = 55.1 bits (131), Expect = 8e-08
Identities = 71/233 (30%), Positives = 102/233 (43%), Gaps = 29/233 (12%)
Query: 108 VSANG---PGEEKLFRSQSADAPGPTERERLKKMLSEGSVG-EVQWEAEFFALQDSNNKL 163
VSA G PG E A PG + L +E S +V+ E L+++ L
Sbjct: 687 VSATGVENPGVE-------ATVPGISAGPILHPGAAEASEKLQVELETRIRGLEEA---L 736
Query: 164 AGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLEQ 223
REA A + EA AEA RLR+RV E E AS G + +LEQ
Sbjct: 737 RQREREAAAELEAALGKCEAAEAEAGRLRERVREAEGSGAS---GGGGGDTTQLRAALEQ 793
Query: 224 LEALVQTKDQEIQTLKSQTGGPREALEA---AEREETQQKVQDLETRNAELE--HQLRAM 278
++ +D ++ L++ + EA + AE E + + + A LE +L +
Sbjct: 794 AREDLRDRDSRLRELEAASACLDEARASRLLAEEEARGLRAELAQREEARLEQSRELEVL 853
Query: 279 ERSLEEARAERERAR---AEVGRAAQLLDVSLFEL----SELREGLARLAEAA 324
L ARA E+ R AE+GRA + + EL E R+GLA L EA+
Sbjct: 854 REQLATARATGEQQRTAAAELGRARDAAEARVAELPAACEEARQGLAELREAS 906
Score = 33.9 bits (76), Expect = 0.20
Identities = 35/131 (26%), Positives = 56/131 (42%), Gaps = 11/131 (8%)
Query: 134 RLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQ 193
+L+ L E + AE F +Q + A A A QQL R EAER RQ
Sbjct: 980 QLEGQLEELGRRHEKTSAEVFQVQREALFMKSERHAAEAQLATAEQQLRGLRTEAERARQ 1039
Query: 194 RVAELEAQAASEVTPTGE-------KEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPR 246
A+ AQ A + + KE ++L++ A + T E++ L+ Q +
Sbjct: 1040 --AQSRAQEALDKAKEKDKKITELSKEVFNLKEALKEQPAALAT--PEVEALRDQVKDLQ 1095
Query: 247 EALEAAEREET 257
+ L+ A R+ +
Sbjct: 1096 QQLQEAARDHS 1106
>gi|7706687 Enah/Vasp-like [Homo sapiens]
Length = 418
Score = 54.3 bits (129), Expect = 1e-07
Identities = 37/148 (25%), Positives = 71/148 (47%), Gaps = 19/148 (12%)
Query: 6 EQPIFSTRAHVFQIDPATKRNWIPA--GKHALT-VSYFYDATRNVYRIISIG--GAKAII 60
EQ I RA V D +K+ W+P G+ + ++ +++ N +R++ + + +I
Sbjct: 5 EQSICQARASVMVYDDTSKK-WVPIKPGQQGFSRINIYHNTASNTFRVVGVKLQDQQVVI 63
Query: 61 NSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQVPPSPLVSAN-------GP 113
N ++ + + + + F QW D+R VYGL FAS++ T + L + N GP
Sbjct: 64 NYSIVKGLKYNQATPTFHQWRDAR--QVYGLNFASKEEATTFSNAMLFALNIMNSQEGGP 121
Query: 114 GEEKLFRSQSADAPGPTERERLKKMLSE 141
++ Q + P P E + ++ + E
Sbjct: 122 SSQR----QVQNGPSPDEMDIQRRQVME 145
>gi|156766068 CDC42 binding protein kinase gamma (DMPK-like) [Homo
sapiens]
Length = 1551
Score = 53.9 bits (128), Expect = 2e-07
Identities = 57/216 (26%), Positives = 82/216 (37%), Gaps = 29/216 (13%)
Query: 110 ANGPGEEKLFRSQSADAPGPTERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALRE 169
A PG++ R E +RL + L+EG G E E Q +L L+E
Sbjct: 478 AGSPGQDSDLRQ---------ELDRLHRELAEGRAGLQAQEQELCRAQGQQEELLQRLQE 528
Query: 170 ANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLEQLEALVQ 229
A A Q A ++ E R ELEAQ +S + +G + + E +A
Sbjct: 529 AQEREAATASQTRALSSQLEEARAAQRELEAQVSSLSRQVTQLQGQWEQRLEESSQAKTI 588
Query: 230 TKDQEIQTLKSQTGGPREAL----EAAEREETQQ-----------KVQDLETRNAELEHQ 274
E + GGP+EA AA RE+ +Q + L+ N L +
Sbjct: 589 HTASETNGMGPPEGGPQEAQLRKEVAALREQLEQAHSHRPSGKEEALCQLQEENRRLSRE 648
Query: 275 LRAMERSL-----EEARAERERARAEVGRAAQLLDV 305
+E L + R E ER E AQL D+
Sbjct: 649 QERLEAELAQEQESKQRLEGERRETESNWEAQLADI 684
Score = 43.9 bits (102), Expect = 2e-04
Identities = 73/260 (28%), Positives = 113/260 (43%), Gaps = 42/260 (16%)
Query: 72 KTSQKFGQWAD-----SRANTVYGLGFASEQHLTQVPPSPLVSANGPGEEKLFRSQSADA 126
+ +Q GQW S+A T++ ASE + PP GP E +L + +A
Sbjct: 567 QVTQLQGQWEQRLEESSQAKTIHT---ASETN-GMGPPE-----GGPQEAQLRKEVAA-- 615
Query: 127 PGPTERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRA 186
RE+L++ S G+ E LQ+ N +L+ A AQ +Q QR
Sbjct: 616 ----LREQLEQAHSHRPSGK---EEALCQLQEENRRLSREQERLEAELAQ--EQESKQRL 666
Query: 187 EAERLRQRVAELEAQAA---SEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTG 243
E ER R+ + EAQ A S V G Q + + E L ++ QTL ++
Sbjct: 667 EGER-RETESNWEAQLADILSWVNDEKVSRGYLQALATKMAEELESLRNVGTQTLPAR-- 723
Query: 244 GPREALEAAEREETQQKVQDLETRNAELEHQLRAME------RSLEEARAERERARAEVG 297
P + A R + + LE ++A LE ++RA + ++EA+ + ER E
Sbjct: 724 -PLDHQWKARRLQKMEASARLELQSA-LEAEIRAKQGLQERLTQVQEAQLQAERRLQEAE 781
Query: 298 RAAQLLDVSLFELSELREGL 317
+ +Q L EL+ LRE L
Sbjct: 782 KQSQALQQ---ELAMLREEL 798
>gi|157738667 FYVE and coiled-coil domain containing 1 [Homo
sapiens]
Length = 1478
Score = 53.5 bits (127), Expect = 2e-07
Identities = 52/193 (26%), Positives = 91/193 (47%), Gaps = 10/193 (5%)
Query: 136 KKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRV 195
+ L EG + +Q A++ ALQ + + G+L A A R + A +R+
Sbjct: 631 RNQLLEGKLQALQ--ADYQALQQRESAIQGSLASLEAEQASIRHLGDQMEASLLAVRKAK 688
Query: 196 AELEAQAASEVTPTGEKEGLGQ--GQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAE 253
++AQ A + KEG Q + +EQ + L + + +E++ L+SQ + +E
Sbjct: 689 EAMKAQMAEKEAILQSKEGECQQLREEVEQCQQLAEARHRELRALESQCQQQTQLIEVLT 748
Query: 254 REETQQKV---QDLETRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFEL 310
E+ QQ V D E R EL QL + LE + E +R +A+V + +L +
Sbjct: 749 AEKGQQGVGPPTDNEAR--ELAAQLALSQAQLEVHQGEVQRLQAQVVDLQAKMRAALDDQ 806
Query: 311 SELREGLARLAEA 323
+++ L+ +AEA
Sbjct: 807 DKVQSQLS-MAEA 818
Score = 42.7 bits (99), Expect = 4e-04
Identities = 37/142 (26%), Positives = 64/142 (45%), Gaps = 15/142 (10%)
Query: 168 REANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLEQLEAL 227
RE A A + QLE + E +RL+ +V +L+A+ + + + + L EA+
Sbjct: 765 RELAAQLALSQAQLEVHQGEVQRLQAQVVDLQAKMRAALDDQDKVQS-----QLSMAEAV 819
Query: 228 VQTKDQEIQTLKSQTGG-----PREALEAAERE-----ETQQKVQDLETRNAELEHQLRA 277
++ +Q LK Q +E L+ +ERE E + Q E L+ +L
Sbjct: 820 LREHKTLVQQLKEQNEALNRAHVQELLQCSEREGALQEERADEAQQREEELRALQEELSQ 879
Query: 278 MERSLEEARAERERARAEVGRA 299
+ S EEA+ E + ++ RA
Sbjct: 880 AKCSSEEAQLEHAELQEQLHRA 901
Score = 38.5 bits (88), Expect = 0.008
Identities = 36/167 (21%), Positives = 75/167 (44%), Gaps = 13/167 (7%)
Query: 149 WEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTP 208
W A D+ + G + AAQ Q+L + ER R +V E+ Q ++++
Sbjct: 371 WLAMAQQKADTASDTKGRQEPIPSDAAQEMQELGEKLQALERERTKVEEVNRQQSAQL-- 428
Query: 209 TGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRN 268
++ + + Q E A ++ +E+ L+ + G + E ++ +++Q+L
Sbjct: 429 ---EQLVKELQLKEDARASLERLVKEMAPLQEELSG-----KGQEADQLWRRLQELLAHT 480
Query: 269 AELEHQLRAMERSLEEARAERERARAEV---GRAAQLLDVSLFELSE 312
+ E +L + R ++ + E+E EV R Q L+ L ++S+
Sbjct: 481 SSWEEELAELRREKKQQQEEKELLEQEVRSLTRQLQFLETQLAQVSQ 527
Score = 38.5 bits (88), Expect = 0.008
Identities = 46/194 (23%), Positives = 85/194 (43%), Gaps = 27/194 (13%)
Query: 122 QSADAPGPTERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQL 181
Q AD T + R + + S+ + + + AL+ K+ R+ +A Q ++L
Sbjct: 377 QKADTASDT-KGRQEPIPSDAAQEMQELGEKLQALERERTKVEEVNRQQSAQLEQLVKEL 435
Query: 182 EAQ---RAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLEQL-----EALVQTKD- 232
+ + RA ERL + +A L+ + + G+GQ +QL E L T
Sbjct: 436 QLKEDARASLERLVKEMAPLQEELS------------GKGQEADQLWRRLQELLAHTSSW 483
Query: 233 ----QEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARAE 288
E++ K Q +E LE R T+Q +Q LET+ A++ + +E ++ +
Sbjct: 484 EEELAELRREKKQQQEEKELLEQEVRSLTRQ-LQFLETQLAQVSQHVSDLEEQKKQLIQD 542
Query: 289 RERARAEVGRAAQL 302
++ +VG +L
Sbjct: 543 KDHLSQQVGMLERL 556
Score = 34.3 bits (77), Expect = 0.16
Identities = 42/194 (21%), Positives = 78/194 (40%), Gaps = 19/194 (9%)
Query: 148 QWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERL----------RQRVAE 197
Q E E ALQ+ ++ + EA A+ ++QL + L ++RV E
Sbjct: 865 QREEELRALQEELSQAKCSSEEAQLEHAELQEQLHRANTDTAELGIQVCALTVEKERVEE 924
Query: 198 LEAQAASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLK-------SQTGGPREALE 250
A A E+ E + Q+ L Q K+ + LK S G + +
Sbjct: 925 ALACAVQELQDAKEAASREREGLERQVAGLQQEKESLQEKLKAAKAAAGSLPGLQAQLAQ 984
Query: 251 AAEREETQQKV--QDLETRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLF 308
A +R ++ Q+ Q+L T +L ++ + L+ A E + R ++ + L +
Sbjct: 985 AEQRAQSLQEAAHQELNTLKFQLSAEIMDYQSRLKNAGEECKSLRGQLEEQGRQLQAAEE 1044
Query: 309 ELSELREGLARLAE 322
+ +L+ A + E
Sbjct: 1045 AVEKLKATQADMGE 1058
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 52.8 bits (125), Expect = 4e-07
Identities = 53/229 (23%), Positives = 102/229 (44%), Gaps = 16/229 (6%)
Query: 101 QVPPSPLVSANGPGEEKLFRSQSADAPGPTERERLKKMLSEGSVGEVQWEAEFFALQDSN 160
+V L+ A + K ++++ + E ER + E E E E
Sbjct: 1142 RVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELE-------- 1193
Query: 161 NKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQS 220
+L+ L EA A+A R+ + AE RLR+ + E + + V K+ G +
Sbjct: 1194 -ELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAEL 1252
Query: 221 LEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKV------QDLETRNAELEHQ 274
EQ+++L + + Q+++ KS+ + L A T+ K + E + +E + +
Sbjct: 1253 GEQVDSLQRVR-QKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIK 1311
Query: 275 LRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEA 323
+ ++R L +A +R R + E G ++LL+ +S+L G A A++
Sbjct: 1312 VEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQS 1360
Score = 43.5 bits (101), Expect = 3e-04
Identities = 48/169 (28%), Positives = 74/169 (43%), Gaps = 29/169 (17%)
Query: 158 DSNNKLAGALREANAAAAQWRQQLEA---QRAEAERLRQRVAELEAQAASEVTPTGEKEG 214
++ +L L +ANA AQWR + EA QR E ++ L Q A E G +
Sbjct: 1401 EAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEE----GVEAA 1456
Query: 215 LGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQ 274
+ SLE+ + +QT+ +++ TL+ + A AA A L+ +
Sbjct: 1457 NAKCSSLEKAKLRLQTESEDV-TLELE-----RATSAA----------------AALDKK 1494
Query: 275 LRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEA 323
R +ER+LEE R + E + E+ A + EL LR G EA
Sbjct: 1495 QRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEA 1543
Score = 40.8 bits (94), Expect = 0.002
Identities = 49/199 (24%), Positives = 85/199 (42%), Gaps = 25/199 (12%)
Query: 114 GEEKLFRSQSADAPGPTERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAA 173
GE+ ++ +A G E E K + + + +V+ E + L + + + A R A
Sbjct: 1584 GEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDR-KLAEKDEECANLRRNHQRA 1642
Query: 174 AAQWRQQLEAQ---RAEAERLRQRVA----ELEAQAASEVTPTGEKEGLGQGQSLEQLEA 226
+ L+A+ R EA RL++++ +LE Q LG + + EA
Sbjct: 1643 VESLQASLDAETRARNEALRLKKKMEGDLNDLELQ-------------LGHA-TRQATEA 1688
Query: 227 LVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEAR 286
T+ + Q + Q G E AAE E + Q LE R + L +L + +LE+
Sbjct: 1689 QAATRLMQAQLKEEQAGRDEEQRLAAELHE---QAQALERRASLLAAELEELRAALEQGE 1745
Query: 287 AERERARAEVGRAAQLLDV 305
R A E+ A + L++
Sbjct: 1746 RSRRLAEQELLEATERLNL 1764
Score = 38.1 bits (87), Expect = 0.011
Identities = 43/161 (26%), Positives = 70/161 (43%), Gaps = 15/161 (9%)
Query: 168 REANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLEQLEAL 227
R +AAAA ++Q +RA ER RQ E E Q E ++E G G L +L
Sbjct: 1483 RATSAAAALDKKQRHLERALEERRRQ---EEEMQRELEAA---QRESRGLGTELFRLRHG 1536
Query: 228 VQTKDQEIQTLKSQTGGPREALEAAEREETQ--QKVQDLETRNAELEHQLRAMERSLEEA 285
+ + ++TLK + +E + + + + +Q+LE LE + ++ +LEEA
Sbjct: 1537 HEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEA 1596
Query: 286 RAERE-------RARAEVGRAAQLLDVSLFELSELREGLAR 319
E R + E+ + +D L E E L R
Sbjct: 1597 EGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRR 1637
Score = 36.2 bits (82), Expect = 0.041
Identities = 57/199 (28%), Positives = 83/199 (41%), Gaps = 29/199 (14%)
Query: 131 ERERLKKMLSEGSVGEVQWEAEFF--ALQDSNNKLAGALREANAAAAQWRQQLEAQRAEA 188
E E+ KK L EG E+Q E AL+ K E + A+ ++L + E
Sbjct: 1574 ELEKTKKAL-EGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEEC 1632
Query: 189 ERLR---QRVAELEAQAASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTG-G 244
LR QR E QA+ + E L + +E ++ L+ Q G
Sbjct: 1633 ANLRRNHQRAVE-SLQASLDAETRARNEALRLKKKMEG----------DLNDLELQLGHA 1681
Query: 245 PREALEA--------AEREETQQKVQDLETRNAELEHQLRAMER--SLEEARAERERARA 294
R+A EA A+ +E Q + + AEL Q +A+ER SL A E RA
Sbjct: 1682 TRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAAL 1741
Query: 295 EVG-RAAQLLDVSLFELSE 312
E G R+ +L + L E +E
Sbjct: 1742 EQGERSRRLAEQELLEATE 1760
>gi|4507869 vasodilator-stimulated phosphoprotein [Homo sapiens]
Length = 380
Score = 52.4 bits (124), Expect = 6e-07
Identities = 42/152 (27%), Positives = 65/152 (42%), Gaps = 30/152 (19%)
Query: 6 EQPIFSTRAHVFQIDPATKRNWIPAGKHALT---VSYFYDATRNVYRIISIG---GAKAI 59
E I S+RA V D KR W+PAG V +++ T N +R++ + +
Sbjct: 3 ETVICSSRATVMLYDDGNKR-WLPAGTGPQAFSRVQIYHNPTANSFRVVGRKMQPDQQVV 61
Query: 60 INSTVTPNMTFTKTSQKFGQWADSRANTVYGLGFASEQHLTQV----------------P 103
IN + + + + + F QW D+R V+GL F S++ Q P
Sbjct: 62 INCAIVRGVKYNQATPNFHQWRDAR--QVWGLNFGSKEDAAQFAAGMASALEALEGGGPP 119
Query: 104 PSPLVSA----NGPGEEKLFRSQSADAPGPTE 131
P P + NGP E++ Q PGP+E
Sbjct: 120 PPPALPTWSVPNGPSPEEV-EQQKRQQPGPSE 150
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 52.4 bits (124), Expect = 6e-07
Identities = 51/183 (27%), Positives = 77/183 (42%), Gaps = 13/183 (7%)
Query: 124 ADAPGPTERERLKKMLSEGSV----GEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQ 179
A+ E E ++ +EG GE Q E+E ++ + + A+W
Sbjct: 1840 AEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEV 1899
Query: 180 QLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLK 239
Q E++ AEA AE EAQ +E E EG + +S E EA Q ++ Q +
Sbjct: 1900 QPESEGAEAPE-----AEKEAQPETESVEALETEGEDEPES-EGAEA--QEAEEAAQEAE 1951
Query: 240 SQTGGPREALEAAE-REETQQKVQDLETRNAELEHQLRAMERSLEEARAERERARAEVGR 298
QT E +E+ E EE Q + +D+E E+E Q E E E A E+
Sbjct: 1952 GQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQE 2011
Query: 299 AAQ 301
A +
Sbjct: 2012 AEE 2014
Score = 43.9 bits (102), Expect = 2e-04
Identities = 47/198 (23%), Positives = 83/198 (41%), Gaps = 14/198 (7%)
Query: 115 EEKLFRSQSADAPGPTERERLK----KMLSEGSVGEVQWEAEFFALQDSNNKLAGALREA 170
E ++ SQ A+ E E ++ ++ ++ + GE Q E+E ++ ++ A EA
Sbjct: 1957 ESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEA 2016
Query: 171 NAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASE----VTPTGEKEGL---GQGQSLEQ 223
+ Q +++ EA+ + + E A E P E+E G+ Q E
Sbjct: 2017 QPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEG 2076
Query: 224 LEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLE 283
EA +++D + Q + + E +EA E E QK + +E E E + + +E
Sbjct: 2077 -EAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEA--PETEGEAQPESEGIE 2133
Query: 284 EARAERERARAEVGRAAQ 301
AE E G AQ
Sbjct: 2134 APEAEGEAQPESEGVEAQ 2151
Score = 43.5 bits (101), Expect = 3e-04
Identities = 51/170 (30%), Positives = 76/170 (44%), Gaps = 20/170 (11%)
Query: 140 SEGSVGEVQWEAEFFALQDSNNKLA----GALREANAAAAQWRQQLEAQRAEAER----- 190
S+G+ G EAE A +S A G +EA A + +EA AE E
Sbjct: 1829 SDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESE 1888
Query: 191 -LRQRVAELEAQAASE--VTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPRE 247
+ AE E Q SE P EKE + +S+E LE + +D+ +S+ +E
Sbjct: 1889 DVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALET--EGEDEP----ESEGAEAQE 1942
Query: 248 ALEAAEREE--TQQKVQDLETRNAELEHQLRAMERSLEEARAERERARAE 295
A EAA+ E TQ + + +E++ AE E Q + + E E + A E
Sbjct: 1943 AEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGE 1992
Score = 37.4 bits (85), Expect = 0.018
Identities = 53/169 (31%), Positives = 72/169 (42%), Gaps = 18/169 (10%)
Query: 145 GEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAE-----AERLRQRVAELE 199
GEVQ EAE A +S + A +EA A + +EA AE AE + E E
Sbjct: 2069 GEVQ-EAEGEAHPESEDVDA---QEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGE 2124
Query: 200 AQAASEVTPTGEKEGLGQGQSL------EQLEALVQTKDQEIQTLKSQTGGPREALEAAE 253
AQ SE E EG Q +S + EA +++ E Q + + E +EA E
Sbjct: 2125 AQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPE 2184
Query: 254 RE-ETQQKVQDLETRNAELEHQ--LRAMERSLEEARAERERARAEVGRA 299
E E Q + + +E AE E Q L +E E A+ E E A
Sbjct: 2185 AEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEA 2233
Score = 36.2 bits (82), Expect = 0.041
Identities = 48/193 (24%), Positives = 79/193 (40%), Gaps = 13/193 (6%)
Query: 115 EEKLFRSQSADAPGPTERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAA 174
EE S +A +E E +++ EG + + +A+ + + A EA A
Sbjct: 2014 EEAQPESDGVEAQPKSEGEEAQEV--EGETQKTEGDAQ---PESDGVEAPEAEEEAQEAE 2068
Query: 175 AQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQ---GQSLEQLEALVQTK 231
+ ++ E+E + + AE EAQ SE E EG Q G + E Q +
Sbjct: 2069 GEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPE 2128
Query: 232 DQEIQT--LKSQTGGPREALEAAERE-ETQQKVQDLETRNAELEHQ--LRAMERSLEEAR 286
+ I+ + + E +EA + E E Q + + +E + AE E Q L +E E
Sbjct: 2129 SEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGE 2188
Query: 287 AERERARAEVGRA 299
A+ E E A
Sbjct: 2189 AQPESEGIEAPEA 2201
Score = 34.3 bits (77), Expect = 0.16
Identities = 35/117 (29%), Positives = 49/117 (41%), Gaps = 13/117 (11%)
Query: 115 EEKLFRSQSADAPGPTERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAA 174
E + +Q A+ E E ++ +EG E Q E+E ++ + L A
Sbjct: 2160 ESEGIEAQEAEEEAQPELEGVEAPEAEG---EAQPESEGIEAPEAEGEAQPELEGVEAPE 2216
Query: 175 AQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEG-----LGQGQSLEQLEA 226
A+ Q E + E AE EAQ SE GEK+G LG GQS E E+
Sbjct: 2217 AEEEAQPEPEGVETPE-----AEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASES 2268
Score = 33.9 bits (76), Expect = 0.20
Identities = 33/123 (26%), Positives = 51/123 (41%), Gaps = 5/123 (4%)
Query: 198 LEAQAASEVTPTGEKEGLGQGQ----SLEQLEALVQTKDQEIQTLKSQTGGPREALEAAE 253
L A+A + T E E + Q +LEQL ++ +++ K T G EA +
Sbjct: 1262 LNARACACATNEDEAERDSEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQ 1321
Query: 254 REETQQKVQDLETRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSEL 313
EET+ + + L+ +LE +E A+ E G Q V L E+ E
Sbjct: 1322 LEETKTE-EGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEG 1380
Query: 314 REG 316
EG
Sbjct: 1381 PEG 1383
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 51.6 bits (122), Expect = 9e-07
Identities = 61/244 (25%), Positives = 104/244 (42%), Gaps = 38/244 (15%)
Query: 114 GEEKLFRSQSADAPGPT-----ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALR 168
GE + R+++ +A E ERL++ + + S + Q E E + + + A +
Sbjct: 1473 GELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQ 1532
Query: 169 EANAAAAQWRQQLEA-----QRAEAERLRQ-----------RVAELEAQAASEVTPTGEK 212
A A + R Q E ++AE ER RQ AEL+++ AS T +
Sbjct: 1533 RALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQL 1592
Query: 213 EGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELE 272
E +SL++ V +E + Q A E AERE + +++ E L+
Sbjct: 1593 E-----RSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQ 1647
Query: 273 HQLRAMERSLEEARAERERARAE------------VGRAAQLLDVSLFELSELREGLARL 320
+ A ++SL +A AE+++ AE R +L + L + +L EG A+
Sbjct: 1648 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1707
Query: 321 AEAA 324
AA
Sbjct: 1708 RLAA 1711
Score = 47.0 bits (110), Expect = 2e-05
Identities = 43/137 (31%), Positives = 65/137 (47%), Gaps = 5/137 (3%)
Query: 164 AGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPT-GEKEGLGQGQSL- 221
A L A AA+ RQ E A+ L +++ + + QA E T E E L Q + L
Sbjct: 2280 AARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA 2339
Query: 222 -EQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMER 280
EQ L + K+Q Q L +T G + LE AER+ + + E + RA R
Sbjct: 2340 QEQARRLQEDKEQMAQQLAEETQGFQRTLE-AERQRQLEMSAEAERLKLRVAEMSRAQAR 2398
Query: 281 SLEEARAERERARAEVG 297
+ E+A+ R++A E+G
Sbjct: 2399 AEEDAQRFRKQAE-EIG 2414
Score = 46.6 bits (109), Expect = 3e-05
Identities = 51/193 (26%), Positives = 86/193 (44%), Gaps = 20/193 (10%)
Query: 131 ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQ---WRQQLEAQRAE 187
E ERLK ++E S + + E + + ++ L A + Q LE QR +
Sbjct: 2381 EAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQ 2440
Query: 188 ----AERLRQRVAELEAQ-------AASEVTPTGEKEGLGQGQSLEQLEALVQT----KD 232
AERLR+ +AELE + A + E + + Q Q L++ +AL Q+ KD
Sbjct: 2441 SDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKD 2500
Query: 233 QEIQTLK--SQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARAERE 290
+Q + Q E L E + QQ ++ + + ++E + + + S+EEAR +
Sbjct: 2501 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2560
Query: 291 RARAEVGRAAQLL 303
A V R + L
Sbjct: 2561 EAEEGVRRKQEEL 2573
Score = 44.7 bits (104), Expect = 1e-04
Identities = 47/172 (27%), Positives = 79/172 (45%), Gaps = 14/172 (8%)
Query: 146 EVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEA---QRAEAERLRQRVA-ELEA- 200
E + +++ + + +L +L+E + A AQ R++ E Q+AEAER R+ ELE
Sbjct: 1575 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERW 1634
Query: 201 --QAASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQ 258
+A + + E + Q +SL Q EA Q ++ E + + G E +RE +
Sbjct: 1635 QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR---GKAEEQAVRQRELAE 1691
Query: 259 QKVQDLETRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFEL 310
Q+++ Q A E+ L RAE E+ + QLL+ L L
Sbjct: 1692 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ----RQLLEEELARL 1739
Score = 43.9 bits (102), Expect = 2e-04
Identities = 52/168 (30%), Positives = 70/168 (41%), Gaps = 38/168 (22%)
Query: 162 KLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSL 221
+LA REA AAA Q RQ+LEA+ A+ AE+E AS+ E
Sbjct: 1735 ELARLQREA-AAATQKRQELEAELAKVR------AEMEVLLASKARAEEESR-------- 1779
Query: 222 EQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERS 281
T ++ Q L+++ G RE E A R L E + Q + E
Sbjct: 1780 -------STSEKSKQRLEAEAGRFRELAEEAAR---------LRALAEEAKRQRQLAEED 1823
Query: 282 LEEARAERERARAE----VGRAAQL---LDVSLFELSELREGLARLAE 322
RAE ER AE +G A +L +++L E E L RLAE
Sbjct: 1824 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAE 1871
Score = 42.7 bits (99), Expect = 4e-04
Identities = 62/226 (27%), Positives = 97/226 (42%), Gaps = 47/226 (20%)
Query: 115 EEKLFRSQSADAPGPTERERL---------KKMLSEGSV-GEVQWEAEFFALQDSNNKLA 164
EE+L Q A+ ERERL ++ L+E + Q E E LQ ++
Sbjct: 1347 EERLAEQQRAE-----ERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ---RMQ 1398
Query: 165 GALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLE-- 222
+ AA +QQ + + E ++LRQ +E E QA + E+ L + +
Sbjct: 1399 EEVVRREEAAVDAQQQKRSIQEELQQLRQS-SEAEIQAKARQAEAAERSRLRIEEEIRVV 1457
Query: 223 --QLEALVQTK---DQEIQTLKSQT----GGPREALEAAEREETQQKVQDLETRNAELE- 272
QLEA + + + E+Q L+++ R+A E AER Q + + R AE+E
Sbjct: 1458 RLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVEL 1517
Query: 273 ---------------HQLRAMER-SLEEARAERERARAEVGRAAQL 302
L+A+E L+ AER +AEV RA Q+
Sbjct: 1518 ASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQV 1563
Score = 41.6 bits (96), Expect = 0.001
Identities = 42/152 (27%), Positives = 66/152 (43%), Gaps = 17/152 (11%)
Query: 173 AAAQWRQQLEAQRAEAERLRQRVAE-------LEAQAASEVTPTGEKEGLGQGQSLEQ-L 224
AA + ++L+A+ EA RLR+R + L +AA + EK Q EQ L
Sbjct: 2006 AALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQEL 2065
Query: 225 EALVQTKDQEIQTLKSQTGGPREALEAAE-------REETQ--QKVQDLETRNAELEHQL 275
+ +Q + + L+ + R A E AE RE Q ++V++ E E Q
Sbjct: 2066 QQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQA 2125
Query: 276 RAMERSLEEARAERERARAEVGRAAQLLDVSL 307
+A ++ A R+ A E R AQ +L
Sbjct: 2126 QARAQAQAAAEKLRKEAEQEAARRAQAEQAAL 2157
Score = 41.6 bits (96), Expect = 0.001
Identities = 43/217 (19%), Positives = 88/217 (40%), Gaps = 24/217 (11%)
Query: 131 ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAER 190
E ERLK+ E + Q +A L+ + A +A AA + +Q +A+ + ++
Sbjct: 2113 EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2172
Query: 191 LRQRVAELEAQAASEVTP-----------------------TGEKEGLGQGQSLEQLEAL 227
++ +AQ E+T E Q +E+
Sbjct: 2173 FAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2232
Query: 228 VQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARA 287
V+ + +E+ LK++ AL +++ TQ+ +Q+ + ++ + + + +EA
Sbjct: 2233 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2292
Query: 288 ERERARAEVGRAAQLLDVSLFELSELREGLARL-AEA 323
R+ A ++ + L + L E + + RL AEA
Sbjct: 2293 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEA 2329
Score = 38.5 bits (88), Expect = 0.008
Identities = 55/219 (25%), Positives = 93/219 (42%), Gaps = 36/219 (16%)
Query: 115 EEKLFRSQSADAPGPTERERLKKMLSEGSVG-EVQWEAEFFALQDSNNKL---------- 163
EE+L R Q A +R+ L+ L++ EV ++ A ++S +
Sbjct: 1733 EEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAE 1792
Query: 164 AGALREANAAAAQWRQQLEA-----QRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQG 218
AG RE AA+ R E Q AE + RQR AE E A ++ GE L
Sbjct: 1793 AGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR-AEAERVLAEKLAAIGEATRLKTE 1851
Query: 219 QSL---------EQLEALVQTKDQEIQTLKSQTGGPREALE--------AAEREETQQK- 260
+ E+L L + + + + L+ Q + +E A++ E +QK
Sbjct: 1852 AEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKG 1911
Query: 261 -VQDLETRNAELEHQLRAMERSLEEARAERERARAEVGR 298
V+D + ++E ++ A++ S E+A A + E+GR
Sbjct: 1912 LVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGR 1950
Score = 38.5 bits (88), Expect = 0.008
Identities = 57/231 (24%), Positives = 95/231 (41%), Gaps = 50/231 (21%)
Query: 135 LKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQ---QLEAQRAEAE-- 189
LK + + G+ + E E ++ + + +A AA+ RQ + E +R EAE
Sbjct: 1930 LKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEER 1989
Query: 190 ------------RLRQRVAE------LEAQAASEVTPTGEKEG-----LGQGQSLEQLEA 226
R R+ E + + A + E+E L Q + ++L+A
Sbjct: 1990 VQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQA 2049
Query: 227 -------LVQTKDQEI-------QTLKSQTGGPREALEAAEREETQQKVQDLETRNAELE 272
VQ K+QE+ Q++ Q G EA A E + +VQ E A+
Sbjct: 2050 EEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ-AEREAAQSR 2108
Query: 273 HQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEA 323
Q+ ER L+++ E+ +ARA+ AA+ L E + AR A+A
Sbjct: 2109 RQVEEAER-LKQSAEEQAQARAQAQAAAEKL------RKEAEQEAARRAQA 2152
Score = 28.5 bits (62), Expect = 8.5
Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 7/50 (14%)
Query: 255 EETQQKVQ------DLETRNAELEHQLRAMERSLEEARAERERARAEVGR 298
EE Q +V DL + A+L R + +S+EE RA+ ERAR++ G+
Sbjct: 533 EENQHRVDGAEWGVDLPSVEAQLGSH-RGLHQSIEEFRAKIERARSDEGQ 581
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 51.6 bits (122), Expect = 9e-07
Identities = 61/244 (25%), Positives = 104/244 (42%), Gaps = 38/244 (15%)
Query: 114 GEEKLFRSQSADAPGPT-----ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALR 168
GE + R+++ +A E ERL++ + + S + Q E E + + + A +
Sbjct: 1477 GELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQ 1536
Query: 169 EANAAAAQWRQQLEA-----QRAEAERLRQ-----------RVAELEAQAASEVTPTGEK 212
A A + R Q E ++AE ER RQ AEL+++ AS T +
Sbjct: 1537 RALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQL 1596
Query: 213 EGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELE 272
E +SL++ V +E + Q A E AERE + +++ E L+
Sbjct: 1597 E-----RSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQ 1651
Query: 273 HQLRAMERSLEEARAERERARAE------------VGRAAQLLDVSLFELSELREGLARL 320
+ A ++SL +A AE+++ AE R +L + L + +L EG A+
Sbjct: 1652 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1711
Query: 321 AEAA 324
AA
Sbjct: 1712 RLAA 1715
Score = 47.0 bits (110), Expect = 2e-05
Identities = 43/137 (31%), Positives = 65/137 (47%), Gaps = 5/137 (3%)
Query: 164 AGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPT-GEKEGLGQGQSL- 221
A L A AA+ RQ E A+ L +++ + + QA E T E E L Q + L
Sbjct: 2284 AARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA 2343
Query: 222 -EQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMER 280
EQ L + K+Q Q L +T G + LE AER+ + + E + RA R
Sbjct: 2344 QEQARRLQEDKEQMAQQLAEETQGFQRTLE-AERQRQLEMSAEAERLKLRVAEMSRAQAR 2402
Query: 281 SLEEARAERERARAEVG 297
+ E+A+ R++A E+G
Sbjct: 2403 AEEDAQRFRKQAE-EIG 2418
Score = 46.6 bits (109), Expect = 3e-05
Identities = 51/193 (26%), Positives = 86/193 (44%), Gaps = 20/193 (10%)
Query: 131 ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQ---WRQQLEAQRAE 187
E ERLK ++E S + + E + + ++ L A + Q LE QR +
Sbjct: 2385 EAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQ 2444
Query: 188 ----AERLRQRVAELEAQ-------AASEVTPTGEKEGLGQGQSLEQLEALVQT----KD 232
AERLR+ +AELE + A + E + + Q Q L++ +AL Q+ KD
Sbjct: 2445 SDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKD 2504
Query: 233 QEIQTLK--SQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARAERE 290
+Q + Q E L E + QQ ++ + + ++E + + + S+EEAR +
Sbjct: 2505 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2564
Query: 291 RARAEVGRAAQLL 303
A V R + L
Sbjct: 2565 EAEEGVRRKQEEL 2577
Score = 44.7 bits (104), Expect = 1e-04
Identities = 47/172 (27%), Positives = 79/172 (45%), Gaps = 14/172 (8%)
Query: 146 EVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEA---QRAEAERLRQRVA-ELEA- 200
E + +++ + + +L +L+E + A AQ R++ E Q+AEAER R+ ELE
Sbjct: 1579 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERW 1638
Query: 201 --QAASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQ 258
+A + + E + Q +SL Q EA Q ++ E + + G E +RE +
Sbjct: 1639 QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR---GKAEEQAVRQRELAE 1695
Query: 259 QKVQDLETRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFEL 310
Q+++ Q A E+ L RAE E+ + QLL+ L L
Sbjct: 1696 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ----RQLLEEELARL 1743
Score = 43.9 bits (102), Expect = 2e-04
Identities = 52/168 (30%), Positives = 70/168 (41%), Gaps = 38/168 (22%)
Query: 162 KLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSL 221
+LA REA AAA Q RQ+LEA+ A+ AE+E AS+ E
Sbjct: 1739 ELARLQREA-AAATQKRQELEAELAKVR------AEMEVLLASKARAEEESR-------- 1783
Query: 222 EQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERS 281
T ++ Q L+++ G RE E A R L E + Q + E
Sbjct: 1784 -------STSEKSKQRLEAEAGRFRELAEEAAR---------LRALAEEAKRQRQLAEED 1827
Query: 282 LEEARAERERARAE----VGRAAQL---LDVSLFELSELREGLARLAE 322
RAE ER AE +G A +L +++L E E L RLAE
Sbjct: 1828 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAE 1875
Score = 42.7 bits (99), Expect = 4e-04
Identities = 62/226 (27%), Positives = 97/226 (42%), Gaps = 47/226 (20%)
Query: 115 EEKLFRSQSADAPGPTERERL---------KKMLSEGSV-GEVQWEAEFFALQDSNNKLA 164
EE+L Q A+ ERERL ++ L+E + Q E E LQ ++
Sbjct: 1351 EERLAEQQRAE-----ERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ---RMQ 1402
Query: 165 GALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLE-- 222
+ AA +QQ + + E ++LRQ +E E QA + E+ L + +
Sbjct: 1403 EEVVRREEAAVDAQQQKRSIQEELQQLRQS-SEAEIQAKARQAEAAERSRLRIEEEIRVV 1461
Query: 223 --QLEALVQTK---DQEIQTLKSQT----GGPREALEAAEREETQQKVQDLETRNAELE- 272
QLEA + + + E+Q L+++ R+A E AER Q + + R AE+E
Sbjct: 1462 RLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVEL 1521
Query: 273 ---------------HQLRAMER-SLEEARAERERARAEVGRAAQL 302
L+A+E L+ AER +AEV RA Q+
Sbjct: 1522 ASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQV 1567
Score = 41.6 bits (96), Expect = 0.001
Identities = 42/152 (27%), Positives = 66/152 (43%), Gaps = 17/152 (11%)
Query: 173 AAAQWRQQLEAQRAEAERLRQRVAE-------LEAQAASEVTPTGEKEGLGQGQSLEQ-L 224
AA + ++L+A+ EA RLR+R + L +AA + EK Q EQ L
Sbjct: 2010 AALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQEL 2069
Query: 225 EALVQTKDQEIQTLKSQTGGPREALEAAE-------REETQ--QKVQDLETRNAELEHQL 275
+ +Q + + L+ + R A E AE RE Q ++V++ E E Q
Sbjct: 2070 QQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQA 2129
Query: 276 RAMERSLEEARAERERARAEVGRAAQLLDVSL 307
+A ++ A R+ A E R AQ +L
Sbjct: 2130 QARAQAQAAAEKLRKEAEQEAARRAQAEQAAL 2161
Score = 41.6 bits (96), Expect = 0.001
Identities = 43/217 (19%), Positives = 88/217 (40%), Gaps = 24/217 (11%)
Query: 131 ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAER 190
E ERLK+ E + Q +A L+ + A +A AA + +Q +A+ + ++
Sbjct: 2117 EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2176
Query: 191 LRQRVAELEAQAASEVTP-----------------------TGEKEGLGQGQSLEQLEAL 227
++ +AQ E+T E Q +E+
Sbjct: 2177 FAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2236
Query: 228 VQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARA 287
V+ + +E+ LK++ AL +++ TQ+ +Q+ + ++ + + + +EA
Sbjct: 2237 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2296
Query: 288 ERERARAEVGRAAQLLDVSLFELSELREGLARL-AEA 323
R+ A ++ + L + L E + + RL AEA
Sbjct: 2297 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEA 2333
Score = 38.5 bits (88), Expect = 0.008
Identities = 55/219 (25%), Positives = 93/219 (42%), Gaps = 36/219 (16%)
Query: 115 EEKLFRSQSADAPGPTERERLKKMLSEGSVG-EVQWEAEFFALQDSNNKL---------- 163
EE+L R Q A +R+ L+ L++ EV ++ A ++S +
Sbjct: 1737 EEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAE 1796
Query: 164 AGALREANAAAAQWRQQLEA-----QRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQG 218
AG RE AA+ R E Q AE + RQR AE E A ++ GE L
Sbjct: 1797 AGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR-AEAERVLAEKLAAIGEATRLKTE 1855
Query: 219 QSL---------EQLEALVQTKDQEIQTLKSQTGGPREALE--------AAEREETQQK- 260
+ E+L L + + + + L+ Q + +E A++ E +QK
Sbjct: 1856 AEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKG 1915
Query: 261 -VQDLETRNAELEHQLRAMERSLEEARAERERARAEVGR 298
V+D + ++E ++ A++ S E+A A + E+GR
Sbjct: 1916 LVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGR 1954
Score = 38.5 bits (88), Expect = 0.008
Identities = 57/231 (24%), Positives = 95/231 (41%), Gaps = 50/231 (21%)
Query: 135 LKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQ---QLEAQRAEAE-- 189
LK + + G+ + E E ++ + + +A AA+ RQ + E +R EAE
Sbjct: 1934 LKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEER 1993
Query: 190 ------------RLRQRVAE------LEAQAASEVTPTGEKEG-----LGQGQSLEQLEA 226
R R+ E + + A + E+E L Q + ++L+A
Sbjct: 1994 VQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQA 2053
Query: 227 -------LVQTKDQEI-------QTLKSQTGGPREALEAAEREETQQKVQDLETRNAELE 272
VQ K+QE+ Q++ Q G EA A E + +VQ E A+
Sbjct: 2054 EEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ-AEREAAQSR 2112
Query: 273 HQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEA 323
Q+ ER L+++ E+ +ARA+ AA+ L E + AR A+A
Sbjct: 2113 RQVEEAER-LKQSAEEQAQARAQAQAAAEKL------RKEAEQEAARRAQA 2156
Score = 28.5 bits (62), Expect = 8.5
Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 7/50 (14%)
Query: 255 EETQQKVQ------DLETRNAELEHQLRAMERSLEEARAERERARAEVGR 298
EE Q +V DL + A+L R + +S+EE RA+ ERAR++ G+
Sbjct: 537 EENQHRVDGAEWGVDLPSVEAQLGSH-RGLHQSIEEFRAKIERARSDEGQ 585
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 51.6 bits (122), Expect = 9e-07
Identities = 61/244 (25%), Positives = 104/244 (42%), Gaps = 38/244 (15%)
Query: 114 GEEKLFRSQSADAPGPT-----ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALR 168
GE + R+++ +A E ERL++ + + S + Q E E + + + A +
Sbjct: 1473 GELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQ 1532
Query: 169 EANAAAAQWRQQLEA-----QRAEAERLRQ-----------RVAELEAQAASEVTPTGEK 212
A A + R Q E ++AE ER RQ AEL+++ AS T +
Sbjct: 1533 RALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQL 1592
Query: 213 EGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELE 272
E +SL++ V +E + Q A E AERE + +++ E L+
Sbjct: 1593 E-----RSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQ 1647
Query: 273 HQLRAMERSLEEARAERERARAE------------VGRAAQLLDVSLFELSELREGLARL 320
+ A ++SL +A AE+++ AE R +L + L + +L EG A+
Sbjct: 1648 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1707
Query: 321 AEAA 324
AA
Sbjct: 1708 RLAA 1711
Score = 47.0 bits (110), Expect = 2e-05
Identities = 43/137 (31%), Positives = 65/137 (47%), Gaps = 5/137 (3%)
Query: 164 AGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPT-GEKEGLGQGQSL- 221
A L A AA+ RQ E A+ L +++ + + QA E T E E L Q + L
Sbjct: 2280 AARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA 2339
Query: 222 -EQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMER 280
EQ L + K+Q Q L +T G + LE AER+ + + E + RA R
Sbjct: 2340 QEQARRLQEDKEQMAQQLAEETQGFQRTLE-AERQRQLEMSAEAERLKLRVAEMSRAQAR 2398
Query: 281 SLEEARAERERARAEVG 297
+ E+A+ R++A E+G
Sbjct: 2399 AEEDAQRFRKQAE-EIG 2414
Score = 46.6 bits (109), Expect = 3e-05
Identities = 51/193 (26%), Positives = 86/193 (44%), Gaps = 20/193 (10%)
Query: 131 ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQ---WRQQLEAQRAE 187
E ERLK ++E S + + E + + ++ L A + Q LE QR +
Sbjct: 2381 EAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQ 2440
Query: 188 ----AERLRQRVAELEAQ-------AASEVTPTGEKEGLGQGQSLEQLEALVQT----KD 232
AERLR+ +AELE + A + E + + Q Q L++ +AL Q+ KD
Sbjct: 2441 SDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKD 2500
Query: 233 QEIQTLK--SQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARAERE 290
+Q + Q E L E + QQ ++ + + ++E + + + S+EEAR +
Sbjct: 2501 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2560
Query: 291 RARAEVGRAAQLL 303
A V R + L
Sbjct: 2561 EAEEGVRRKQEEL 2573
Score = 44.7 bits (104), Expect = 1e-04
Identities = 47/172 (27%), Positives = 79/172 (45%), Gaps = 14/172 (8%)
Query: 146 EVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEA---QRAEAERLRQRVA-ELEA- 200
E + +++ + + +L +L+E + A AQ R++ E Q+AEAER R+ ELE
Sbjct: 1575 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERW 1634
Query: 201 --QAASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQ 258
+A + + E + Q +SL Q EA Q ++ E + + G E +RE +
Sbjct: 1635 QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR---GKAEEQAVRQRELAE 1691
Query: 259 QKVQDLETRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFEL 310
Q+++ Q A E+ L RAE E+ + QLL+ L L
Sbjct: 1692 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ----RQLLEEELARL 1739
Score = 43.9 bits (102), Expect = 2e-04
Identities = 52/168 (30%), Positives = 70/168 (41%), Gaps = 38/168 (22%)
Query: 162 KLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSL 221
+LA REA AAA Q RQ+LEA+ A+ AE+E AS+ E
Sbjct: 1735 ELARLQREA-AAATQKRQELEAELAKVR------AEMEVLLASKARAEEESR-------- 1779
Query: 222 EQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERS 281
T ++ Q L+++ G RE E A R L E + Q + E
Sbjct: 1780 -------STSEKSKQRLEAEAGRFRELAEEAAR---------LRALAEEAKRQRQLAEED 1823
Query: 282 LEEARAERERARAE----VGRAAQL---LDVSLFELSELREGLARLAE 322
RAE ER AE +G A +L +++L E E L RLAE
Sbjct: 1824 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAE 1871
Score = 42.7 bits (99), Expect = 4e-04
Identities = 62/226 (27%), Positives = 97/226 (42%), Gaps = 47/226 (20%)
Query: 115 EEKLFRSQSADAPGPTERERL---------KKMLSEGSV-GEVQWEAEFFALQDSNNKLA 164
EE+L Q A+ ERERL ++ L+E + Q E E LQ ++
Sbjct: 1347 EERLAEQQRAE-----ERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ---RMQ 1398
Query: 165 GALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLE-- 222
+ AA +QQ + + E ++LRQ +E E QA + E+ L + +
Sbjct: 1399 EEVVRREEAAVDAQQQKRSIQEELQQLRQS-SEAEIQAKARQAEAAERSRLRIEEEIRVV 1457
Query: 223 --QLEALVQTK---DQEIQTLKSQT----GGPREALEAAEREETQQKVQDLETRNAELE- 272
QLEA + + + E+Q L+++ R+A E AER Q + + R AE+E
Sbjct: 1458 RLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVEL 1517
Query: 273 ---------------HQLRAMER-SLEEARAERERARAEVGRAAQL 302
L+A+E L+ AER +AEV RA Q+
Sbjct: 1518 ASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQV 1563
Score = 41.6 bits (96), Expect = 0.001
Identities = 42/152 (27%), Positives = 66/152 (43%), Gaps = 17/152 (11%)
Query: 173 AAAQWRQQLEAQRAEAERLRQRVAE-------LEAQAASEVTPTGEKEGLGQGQSLEQ-L 224
AA + ++L+A+ EA RLR+R + L +AA + EK Q EQ L
Sbjct: 2006 AALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQEL 2065
Query: 225 EALVQTKDQEIQTLKSQTGGPREALEAAE-------REETQ--QKVQDLETRNAELEHQL 275
+ +Q + + L+ + R A E AE RE Q ++V++ E E Q
Sbjct: 2066 QQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQA 2125
Query: 276 RAMERSLEEARAERERARAEVGRAAQLLDVSL 307
+A ++ A R+ A E R AQ +L
Sbjct: 2126 QARAQAQAAAEKLRKEAEQEAARRAQAEQAAL 2157
Score = 41.6 bits (96), Expect = 0.001
Identities = 43/217 (19%), Positives = 88/217 (40%), Gaps = 24/217 (11%)
Query: 131 ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAER 190
E ERLK+ E + Q +A L+ + A +A AA + +Q +A+ + ++
Sbjct: 2113 EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2172
Query: 191 LRQRVAELEAQAASEVTP-----------------------TGEKEGLGQGQSLEQLEAL 227
++ +AQ E+T E Q +E+
Sbjct: 2173 FAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2232
Query: 228 VQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARA 287
V+ + +E+ LK++ AL +++ TQ+ +Q+ + ++ + + + +EA
Sbjct: 2233 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2292
Query: 288 ERERARAEVGRAAQLLDVSLFELSELREGLARL-AEA 323
R+ A ++ + L + L E + + RL AEA
Sbjct: 2293 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEA 2329
Score = 38.5 bits (88), Expect = 0.008
Identities = 55/219 (25%), Positives = 93/219 (42%), Gaps = 36/219 (16%)
Query: 115 EEKLFRSQSADAPGPTERERLKKMLSEGSVG-EVQWEAEFFALQDSNNKL---------- 163
EE+L R Q A +R+ L+ L++ EV ++ A ++S +
Sbjct: 1733 EEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAE 1792
Query: 164 AGALREANAAAAQWRQQLEA-----QRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQG 218
AG RE AA+ R E Q AE + RQR AE E A ++ GE L
Sbjct: 1793 AGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR-AEAERVLAEKLAAIGEATRLKTE 1851
Query: 219 QSL---------EQLEALVQTKDQEIQTLKSQTGGPREALE--------AAEREETQQK- 260
+ E+L L + + + + L+ Q + +E A++ E +QK
Sbjct: 1852 AEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKG 1911
Query: 261 -VQDLETRNAELEHQLRAMERSLEEARAERERARAEVGR 298
V+D + ++E ++ A++ S E+A A + E+GR
Sbjct: 1912 LVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGR 1950
Score = 38.5 bits (88), Expect = 0.008
Identities = 57/231 (24%), Positives = 95/231 (41%), Gaps = 50/231 (21%)
Query: 135 LKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQ---QLEAQRAEAE-- 189
LK + + G+ + E E ++ + + +A AA+ RQ + E +R EAE
Sbjct: 1930 LKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEER 1989
Query: 190 ------------RLRQRVAE------LEAQAASEVTPTGEKEG-----LGQGQSLEQLEA 226
R R+ E + + A + E+E L Q + ++L+A
Sbjct: 1990 VQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQA 2049
Query: 227 -------LVQTKDQEI-------QTLKSQTGGPREALEAAEREETQQKVQDLETRNAELE 272
VQ K+QE+ Q++ Q G EA A E + +VQ E A+
Sbjct: 2050 EEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ-AEREAAQSR 2108
Query: 273 HQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEA 323
Q+ ER L+++ E+ +ARA+ AA+ L E + AR A+A
Sbjct: 2109 RQVEEAER-LKQSAEEQAQARAQAQAAAEKL------RKEAEQEAARRAQA 2152
Score = 28.5 bits (62), Expect = 8.5
Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 7/50 (14%)
Query: 255 EETQQKVQ------DLETRNAELEHQLRAMERSLEEARAERERARAEVGR 298
EE Q +V DL + A+L R + +S+EE RA+ ERAR++ G+
Sbjct: 533 EENQHRVDGAEWGVDLPSVEAQLGSH-RGLHQSIEEFRAKIERARSDEGQ 581
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 51.6 bits (122), Expect = 9e-07
Identities = 61/244 (25%), Positives = 104/244 (42%), Gaps = 38/244 (15%)
Query: 114 GEEKLFRSQSADAPGPT-----ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALR 168
GE + R+++ +A E ERL++ + + S + Q E E + + + A +
Sbjct: 1441 GELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQ 1500
Query: 169 EANAAAAQWRQQLEA-----QRAEAERLRQ-----------RVAELEAQAASEVTPTGEK 212
A A + R Q E ++AE ER RQ AEL+++ AS T +
Sbjct: 1501 RALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQL 1560
Query: 213 EGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELE 272
E +SL++ V +E + Q A E AERE + +++ E L+
Sbjct: 1561 E-----RSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQ 1615
Query: 273 HQLRAMERSLEEARAERERARAE------------VGRAAQLLDVSLFELSELREGLARL 320
+ A ++SL +A AE+++ AE R +L + L + +L EG A+
Sbjct: 1616 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1675
Query: 321 AEAA 324
AA
Sbjct: 1676 RLAA 1679
Score = 47.0 bits (110), Expect = 2e-05
Identities = 43/137 (31%), Positives = 65/137 (47%), Gaps = 5/137 (3%)
Query: 164 AGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPT-GEKEGLGQGQSL- 221
A L A AA+ RQ E A+ L +++ + + QA E T E E L Q + L
Sbjct: 2248 AARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA 2307
Query: 222 -EQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMER 280
EQ L + K+Q Q L +T G + LE AER+ + + E + RA R
Sbjct: 2308 QEQARRLQEDKEQMAQQLAEETQGFQRTLE-AERQRQLEMSAEAERLKLRVAEMSRAQAR 2366
Query: 281 SLEEARAERERARAEVG 297
+ E+A+ R++A E+G
Sbjct: 2367 AEEDAQRFRKQAE-EIG 2382
Score = 46.6 bits (109), Expect = 3e-05
Identities = 51/193 (26%), Positives = 86/193 (44%), Gaps = 20/193 (10%)
Query: 131 ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQ---WRQQLEAQRAE 187
E ERLK ++E S + + E + + ++ L A + Q LE QR +
Sbjct: 2349 EAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQ 2408
Query: 188 ----AERLRQRVAELEAQ-------AASEVTPTGEKEGLGQGQSLEQLEALVQT----KD 232
AERLR+ +AELE + A + E + + Q Q L++ +AL Q+ KD
Sbjct: 2409 SDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKD 2468
Query: 233 QEIQTLK--SQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARAERE 290
+Q + Q E L E + QQ ++ + + ++E + + + S+EEAR +
Sbjct: 2469 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2528
Query: 291 RARAEVGRAAQLL 303
A V R + L
Sbjct: 2529 EAEEGVRRKQEEL 2541
Score = 44.7 bits (104), Expect = 1e-04
Identities = 47/172 (27%), Positives = 79/172 (45%), Gaps = 14/172 (8%)
Query: 146 EVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEA---QRAEAERLRQRVA-ELEA- 200
E + +++ + + +L +L+E + A AQ R++ E Q+AEAER R+ ELE
Sbjct: 1543 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERW 1602
Query: 201 --QAASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQ 258
+A + + E + Q +SL Q EA Q ++ E + + G E +RE +
Sbjct: 1603 QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR---GKAEEQAVRQRELAE 1659
Query: 259 QKVQDLETRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFEL 310
Q+++ Q A E+ L RAE E+ + QLL+ L L
Sbjct: 1660 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ----RQLLEEELARL 1707
Score = 43.9 bits (102), Expect = 2e-04
Identities = 52/168 (30%), Positives = 70/168 (41%), Gaps = 38/168 (22%)
Query: 162 KLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSL 221
+LA REA AAA Q RQ+LEA+ A+ AE+E AS+ E
Sbjct: 1703 ELARLQREA-AAATQKRQELEAELAKVR------AEMEVLLASKARAEEESR-------- 1747
Query: 222 EQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERS 281
T ++ Q L+++ G RE E A R L E + Q + E
Sbjct: 1748 -------STSEKSKQRLEAEAGRFRELAEEAAR---------LRALAEEAKRQRQLAEED 1791
Query: 282 LEEARAERERARAE----VGRAAQL---LDVSLFELSELREGLARLAE 322
RAE ER AE +G A +L +++L E E L RLAE
Sbjct: 1792 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAE 1839
Score = 42.7 bits (99), Expect = 4e-04
Identities = 62/226 (27%), Positives = 97/226 (42%), Gaps = 47/226 (20%)
Query: 115 EEKLFRSQSADAPGPTERERL---------KKMLSEGSV-GEVQWEAEFFALQDSNNKLA 164
EE+L Q A+ ERERL ++ L+E + Q E E LQ ++
Sbjct: 1315 EERLAEQQRAE-----ERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ---RMQ 1366
Query: 165 GALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLE-- 222
+ AA +QQ + + E ++LRQ +E E QA + E+ L + +
Sbjct: 1367 EEVVRREEAAVDAQQQKRSIQEELQQLRQS-SEAEIQAKARQAEAAERSRLRIEEEIRVV 1425
Query: 223 --QLEALVQTK---DQEIQTLKSQT----GGPREALEAAEREETQQKVQDLETRNAELE- 272
QLEA + + + E+Q L+++ R+A E AER Q + + R AE+E
Sbjct: 1426 RLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVEL 1485
Query: 273 ---------------HQLRAMER-SLEEARAERERARAEVGRAAQL 302
L+A+E L+ AER +AEV RA Q+
Sbjct: 1486 ASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQV 1531
Score = 41.6 bits (96), Expect = 0.001
Identities = 42/152 (27%), Positives = 66/152 (43%), Gaps = 17/152 (11%)
Query: 173 AAAQWRQQLEAQRAEAERLRQRVAE-------LEAQAASEVTPTGEKEGLGQGQSLEQ-L 224
AA + ++L+A+ EA RLR+R + L +AA + EK Q EQ L
Sbjct: 1974 AALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQEL 2033
Query: 225 EALVQTKDQEIQTLKSQTGGPREALEAAE-------REETQ--QKVQDLETRNAELEHQL 275
+ +Q + + L+ + R A E AE RE Q ++V++ E E Q
Sbjct: 2034 QQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQA 2093
Query: 276 RAMERSLEEARAERERARAEVGRAAQLLDVSL 307
+A ++ A R+ A E R AQ +L
Sbjct: 2094 QARAQAQAAAEKLRKEAEQEAARRAQAEQAAL 2125
Score = 41.6 bits (96), Expect = 0.001
Identities = 43/217 (19%), Positives = 88/217 (40%), Gaps = 24/217 (11%)
Query: 131 ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAER 190
E ERLK+ E + Q +A L+ + A +A AA + +Q +A+ + ++
Sbjct: 2081 EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2140
Query: 191 LRQRVAELEAQAASEVTP-----------------------TGEKEGLGQGQSLEQLEAL 227
++ +AQ E+T E Q +E+
Sbjct: 2141 FAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2200
Query: 228 VQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARA 287
V+ + +E+ LK++ AL +++ TQ+ +Q+ + ++ + + + +EA
Sbjct: 2201 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2260
Query: 288 ERERARAEVGRAAQLLDVSLFELSELREGLARL-AEA 323
R+ A ++ + L + L E + + RL AEA
Sbjct: 2261 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEA 2297
Score = 38.5 bits (88), Expect = 0.008
Identities = 55/219 (25%), Positives = 93/219 (42%), Gaps = 36/219 (16%)
Query: 115 EEKLFRSQSADAPGPTERERLKKMLSEGSVG-EVQWEAEFFALQDSNNKL---------- 163
EE+L R Q A +R+ L+ L++ EV ++ A ++S +
Sbjct: 1701 EEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAE 1760
Query: 164 AGALREANAAAAQWRQQLEA-----QRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQG 218
AG RE AA+ R E Q AE + RQR AE E A ++ GE L
Sbjct: 1761 AGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR-AEAERVLAEKLAAIGEATRLKTE 1819
Query: 219 QSL---------EQLEALVQTKDQEIQTLKSQTGGPREALE--------AAEREETQQK- 260
+ E+L L + + + + L+ Q + +E A++ E +QK
Sbjct: 1820 AEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKG 1879
Query: 261 -VQDLETRNAELEHQLRAMERSLEEARAERERARAEVGR 298
V+D + ++E ++ A++ S E+A A + E+GR
Sbjct: 1880 LVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGR 1918
Score = 38.5 bits (88), Expect = 0.008
Identities = 57/231 (24%), Positives = 95/231 (41%), Gaps = 50/231 (21%)
Query: 135 LKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQ---QLEAQRAEAE-- 189
LK + + G+ + E E ++ + + +A AA+ RQ + E +R EAE
Sbjct: 1898 LKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEER 1957
Query: 190 ------------RLRQRVAE------LEAQAASEVTPTGEKEG-----LGQGQSLEQLEA 226
R R+ E + + A + E+E L Q + ++L+A
Sbjct: 1958 VQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQA 2017
Query: 227 -------LVQTKDQEI-------QTLKSQTGGPREALEAAEREETQQKVQDLETRNAELE 272
VQ K+QE+ Q++ Q G EA A E + +VQ E A+
Sbjct: 2018 EEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ-AEREAAQSR 2076
Query: 273 HQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEA 323
Q+ ER L+++ E+ +ARA+ AA+ L E + AR A+A
Sbjct: 2077 RQVEEAER-LKQSAEEQAQARAQAQAAAEKL------RKEAEQEAARRAQA 2120
Score = 28.5 bits (62), Expect = 8.5
Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 7/50 (14%)
Query: 255 EETQQKVQ------DLETRNAELEHQLRAMERSLEEARAERERARAEVGR 298
EE Q +V DL + A+L R + +S+EE RA+ ERAR++ G+
Sbjct: 501 EENQHRVDGAEWGVDLPSVEAQLGSH-RGLHQSIEEFRAKIERARSDEGQ 549
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 51.6 bits (122), Expect = 9e-07
Identities = 61/244 (25%), Positives = 104/244 (42%), Gaps = 38/244 (15%)
Query: 114 GEEKLFRSQSADAPGPT-----ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALR 168
GE + R+++ +A E ERL++ + + S + Q E E + + + A +
Sbjct: 1610 GELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQ 1669
Query: 169 EANAAAAQWRQQLEA-----QRAEAERLRQ-----------RVAELEAQAASEVTPTGEK 212
A A + R Q E ++AE ER RQ AEL+++ AS T +
Sbjct: 1670 RALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQL 1729
Query: 213 EGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELE 272
E +SL++ V +E + Q A E AERE + +++ E L+
Sbjct: 1730 E-----RSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQ 1784
Query: 273 HQLRAMERSLEEARAERERARAE------------VGRAAQLLDVSLFELSELREGLARL 320
+ A ++SL +A AE+++ AE R +L + L + +L EG A+
Sbjct: 1785 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1844
Query: 321 AEAA 324
AA
Sbjct: 1845 RLAA 1848
Score = 47.0 bits (110), Expect = 2e-05
Identities = 43/137 (31%), Positives = 65/137 (47%), Gaps = 5/137 (3%)
Query: 164 AGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPT-GEKEGLGQGQSL- 221
A L A AA+ RQ E A+ L +++ + + QA E T E E L Q + L
Sbjct: 2417 AARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA 2476
Query: 222 -EQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMER 280
EQ L + K+Q Q L +T G + LE AER+ + + E + RA R
Sbjct: 2477 QEQARRLQEDKEQMAQQLAEETQGFQRTLE-AERQRQLEMSAEAERLKLRVAEMSRAQAR 2535
Query: 281 SLEEARAERERARAEVG 297
+ E+A+ R++A E+G
Sbjct: 2536 AEEDAQRFRKQAE-EIG 2551
Score = 46.6 bits (109), Expect = 3e-05
Identities = 51/193 (26%), Positives = 86/193 (44%), Gaps = 20/193 (10%)
Query: 131 ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQ---WRQQLEAQRAE 187
E ERLK ++E S + + E + + ++ L A + Q LE QR +
Sbjct: 2518 EAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQ 2577
Query: 188 ----AERLRQRVAELEAQ-------AASEVTPTGEKEGLGQGQSLEQLEALVQT----KD 232
AERLR+ +AELE + A + E + + Q Q L++ +AL Q+ KD
Sbjct: 2578 SDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKD 2637
Query: 233 QEIQTLK--SQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARAERE 290
+Q + Q E L E + QQ ++ + + ++E + + + S+EEAR +
Sbjct: 2638 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2697
Query: 291 RARAEVGRAAQLL 303
A V R + L
Sbjct: 2698 EAEEGVRRKQEEL 2710
Score = 44.7 bits (104), Expect = 1e-04
Identities = 47/172 (27%), Positives = 79/172 (45%), Gaps = 14/172 (8%)
Query: 146 EVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEA---QRAEAERLRQRVA-ELEA- 200
E + +++ + + +L +L+E + A AQ R++ E Q+AEAER R+ ELE
Sbjct: 1712 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERW 1771
Query: 201 --QAASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQ 258
+A + + E + Q +SL Q EA Q ++ E + + G E +RE +
Sbjct: 1772 QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR---GKAEEQAVRQRELAE 1828
Query: 259 QKVQDLETRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFEL 310
Q+++ Q A E+ L RAE E+ + QLL+ L L
Sbjct: 1829 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ----RQLLEEELARL 1876
Score = 43.9 bits (102), Expect = 2e-04
Identities = 52/168 (30%), Positives = 70/168 (41%), Gaps = 38/168 (22%)
Query: 162 KLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSL 221
+LA REA AAA Q RQ+LEA+ A+ AE+E AS+ E
Sbjct: 1872 ELARLQREA-AAATQKRQELEAELAKVR------AEMEVLLASKARAEEESR-------- 1916
Query: 222 EQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERS 281
T ++ Q L+++ G RE E A R L E + Q + E
Sbjct: 1917 -------STSEKSKQRLEAEAGRFRELAEEAAR---------LRALAEEAKRQRQLAEED 1960
Query: 282 LEEARAERERARAE----VGRAAQL---LDVSLFELSELREGLARLAE 322
RAE ER AE +G A +L +++L E E L RLAE
Sbjct: 1961 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAE 2008
Score = 42.7 bits (99), Expect = 4e-04
Identities = 62/226 (27%), Positives = 97/226 (42%), Gaps = 47/226 (20%)
Query: 115 EEKLFRSQSADAPGPTERERL---------KKMLSEGSV-GEVQWEAEFFALQDSNNKLA 164
EE+L Q A+ ERERL ++ L+E + Q E E LQ ++
Sbjct: 1484 EERLAEQQRAE-----ERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ---RMQ 1535
Query: 165 GALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLE-- 222
+ AA +QQ + + E ++LRQ +E E QA + E+ L + +
Sbjct: 1536 EEVVRREEAAVDAQQQKRSIQEELQQLRQS-SEAEIQAKARQAEAAERSRLRIEEEIRVV 1594
Query: 223 --QLEALVQTK---DQEIQTLKSQT----GGPREALEAAEREETQQKVQDLETRNAELE- 272
QLEA + + + E+Q L+++ R+A E AER Q + + R AE+E
Sbjct: 1595 RLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVEL 1654
Query: 273 ---------------HQLRAMER-SLEEARAERERARAEVGRAAQL 302
L+A+E L+ AER +AEV RA Q+
Sbjct: 1655 ASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQV 1700
Score = 41.6 bits (96), Expect = 0.001
Identities = 42/152 (27%), Positives = 66/152 (43%), Gaps = 17/152 (11%)
Query: 173 AAAQWRQQLEAQRAEAERLRQRVAE-------LEAQAASEVTPTGEKEGLGQGQSLEQ-L 224
AA + ++L+A+ EA RLR+R + L +AA + EK Q EQ L
Sbjct: 2143 AALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQEL 2202
Query: 225 EALVQTKDQEIQTLKSQTGGPREALEAAE-------REETQ--QKVQDLETRNAELEHQL 275
+ +Q + + L+ + R A E AE RE Q ++V++ E E Q
Sbjct: 2203 QQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQA 2262
Query: 276 RAMERSLEEARAERERARAEVGRAAQLLDVSL 307
+A ++ A R+ A E R AQ +L
Sbjct: 2263 QARAQAQAAAEKLRKEAEQEAARRAQAEQAAL 2294
Score = 41.6 bits (96), Expect = 0.001
Identities = 43/217 (19%), Positives = 88/217 (40%), Gaps = 24/217 (11%)
Query: 131 ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAER 190
E ERLK+ E + Q +A L+ + A +A AA + +Q +A+ + ++
Sbjct: 2250 EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2309
Query: 191 LRQRVAELEAQAASEVTP-----------------------TGEKEGLGQGQSLEQLEAL 227
++ +AQ E+T E Q +E+
Sbjct: 2310 FAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2369
Query: 228 VQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARA 287
V+ + +E+ LK++ AL +++ TQ+ +Q+ + ++ + + + +EA
Sbjct: 2370 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2429
Query: 288 ERERARAEVGRAAQLLDVSLFELSELREGLARL-AEA 323
R+ A ++ + L + L E + + RL AEA
Sbjct: 2430 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEA 2466
Score = 38.5 bits (88), Expect = 0.008
Identities = 55/219 (25%), Positives = 93/219 (42%), Gaps = 36/219 (16%)
Query: 115 EEKLFRSQSADAPGPTERERLKKMLSEGSVG-EVQWEAEFFALQDSNNKL---------- 163
EE+L R Q A +R+ L+ L++ EV ++ A ++S +
Sbjct: 1870 EEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAE 1929
Query: 164 AGALREANAAAAQWRQQLEA-----QRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQG 218
AG RE AA+ R E Q AE + RQR AE E A ++ GE L
Sbjct: 1930 AGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR-AEAERVLAEKLAAIGEATRLKTE 1988
Query: 219 QSL---------EQLEALVQTKDQEIQTLKSQTGGPREALE--------AAEREETQQK- 260
+ E+L L + + + + L+ Q + +E A++ E +QK
Sbjct: 1989 AEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKG 2048
Query: 261 -VQDLETRNAELEHQLRAMERSLEEARAERERARAEVGR 298
V+D + ++E ++ A++ S E+A A + E+GR
Sbjct: 2049 LVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGR 2087
Score = 38.5 bits (88), Expect = 0.008
Identities = 57/231 (24%), Positives = 95/231 (41%), Gaps = 50/231 (21%)
Query: 135 LKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQ---QLEAQRAEAE-- 189
LK + + G+ + E E ++ + + +A AA+ RQ + E +R EAE
Sbjct: 2067 LKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEER 2126
Query: 190 ------------RLRQRVAE------LEAQAASEVTPTGEKEG-----LGQGQSLEQLEA 226
R R+ E + + A + E+E L Q + ++L+A
Sbjct: 2127 VQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQA 2186
Query: 227 -------LVQTKDQEI-------QTLKSQTGGPREALEAAEREETQQKVQDLETRNAELE 272
VQ K+QE+ Q++ Q G EA A E + +VQ E A+
Sbjct: 2187 EEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ-AEREAAQSR 2245
Query: 273 HQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEA 323
Q+ ER L+++ E+ +ARA+ AA+ L E + AR A+A
Sbjct: 2246 RQVEEAER-LKQSAEEQAQARAQAQAAAEKL------RKEAEQEAARRAQA 2289
Score = 28.5 bits (62), Expect = 8.5
Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 7/50 (14%)
Query: 255 EETQQKVQ------DLETRNAELEHQLRAMERSLEEARAERERARAEVGR 298
EE Q +V DL + A+L R + +S+EE RA+ ERAR++ G+
Sbjct: 670 EENQHRVDGAEWGVDLPSVEAQLGSH-RGLHQSIEEFRAKIERARSDEGQ 718
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 51.6 bits (122), Expect = 9e-07
Identities = 61/244 (25%), Positives = 104/244 (42%), Gaps = 38/244 (15%)
Query: 114 GEEKLFRSQSADAPGPT-----ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALR 168
GE + R+++ +A E ERL++ + + S + Q E E + + + A +
Sbjct: 1451 GELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQ 1510
Query: 169 EANAAAAQWRQQLEA-----QRAEAERLRQ-----------RVAELEAQAASEVTPTGEK 212
A A + R Q E ++AE ER RQ AEL+++ AS T +
Sbjct: 1511 RALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQL 1570
Query: 213 EGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELE 272
E +SL++ V +E + Q A E AERE + +++ E L+
Sbjct: 1571 E-----RSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQ 1625
Query: 273 HQLRAMERSLEEARAERERARAE------------VGRAAQLLDVSLFELSELREGLARL 320
+ A ++SL +A AE+++ AE R +L + L + +L EG A+
Sbjct: 1626 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1685
Query: 321 AEAA 324
AA
Sbjct: 1686 RLAA 1689
Score = 47.0 bits (110), Expect = 2e-05
Identities = 43/137 (31%), Positives = 65/137 (47%), Gaps = 5/137 (3%)
Query: 164 AGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPT-GEKEGLGQGQSL- 221
A L A AA+ RQ E A+ L +++ + + QA E T E E L Q + L
Sbjct: 2258 AARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA 2317
Query: 222 -EQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMER 280
EQ L + K+Q Q L +T G + LE AER+ + + E + RA R
Sbjct: 2318 QEQARRLQEDKEQMAQQLAEETQGFQRTLE-AERQRQLEMSAEAERLKLRVAEMSRAQAR 2376
Query: 281 SLEEARAERERARAEVG 297
+ E+A+ R++A E+G
Sbjct: 2377 AEEDAQRFRKQAE-EIG 2392
Score = 46.6 bits (109), Expect = 3e-05
Identities = 51/193 (26%), Positives = 86/193 (44%), Gaps = 20/193 (10%)
Query: 131 ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQ---WRQQLEAQRAE 187
E ERLK ++E S + + E + + ++ L A + Q LE QR +
Sbjct: 2359 EAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQ 2418
Query: 188 ----AERLRQRVAELEAQ-------AASEVTPTGEKEGLGQGQSLEQLEALVQT----KD 232
AERLR+ +AELE + A + E + + Q Q L++ +AL Q+ KD
Sbjct: 2419 SDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKD 2478
Query: 233 QEIQTLK--SQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARAERE 290
+Q + Q E L E + QQ ++ + + ++E + + + S+EEAR +
Sbjct: 2479 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2538
Query: 291 RARAEVGRAAQLL 303
A V R + L
Sbjct: 2539 EAEEGVRRKQEEL 2551
Score = 44.7 bits (104), Expect = 1e-04
Identities = 47/172 (27%), Positives = 79/172 (45%), Gaps = 14/172 (8%)
Query: 146 EVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEA---QRAEAERLRQRVA-ELEA- 200
E + +++ + + +L +L+E + A AQ R++ E Q+AEAER R+ ELE
Sbjct: 1553 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERW 1612
Query: 201 --QAASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQ 258
+A + + E + Q +SL Q EA Q ++ E + + G E +RE +
Sbjct: 1613 QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR---GKAEEQAVRQRELAE 1669
Query: 259 QKVQDLETRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFEL 310
Q+++ Q A E+ L RAE E+ + QLL+ L L
Sbjct: 1670 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ----RQLLEEELARL 1717
Score = 43.9 bits (102), Expect = 2e-04
Identities = 52/168 (30%), Positives = 70/168 (41%), Gaps = 38/168 (22%)
Query: 162 KLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSL 221
+LA REA AAA Q RQ+LEA+ A+ AE+E AS+ E
Sbjct: 1713 ELARLQREA-AAATQKRQELEAELAKVR------AEMEVLLASKARAEEESR-------- 1757
Query: 222 EQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERS 281
T ++ Q L+++ G RE E A R L E + Q + E
Sbjct: 1758 -------STSEKSKQRLEAEAGRFRELAEEAAR---------LRALAEEAKRQRQLAEED 1801
Query: 282 LEEARAERERARAE----VGRAAQL---LDVSLFELSELREGLARLAE 322
RAE ER AE +G A +L +++L E E L RLAE
Sbjct: 1802 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAE 1849
Score = 42.7 bits (99), Expect = 4e-04
Identities = 62/226 (27%), Positives = 97/226 (42%), Gaps = 47/226 (20%)
Query: 115 EEKLFRSQSADAPGPTERERL---------KKMLSEGSV-GEVQWEAEFFALQDSNNKLA 164
EE+L Q A+ ERERL ++ L+E + Q E E LQ ++
Sbjct: 1325 EERLAEQQRAE-----ERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ---RMQ 1376
Query: 165 GALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLE-- 222
+ AA +QQ + + E ++LRQ +E E QA + E+ L + +
Sbjct: 1377 EEVVRREEAAVDAQQQKRSIQEELQQLRQS-SEAEIQAKARQAEAAERSRLRIEEEIRVV 1435
Query: 223 --QLEALVQTK---DQEIQTLKSQT----GGPREALEAAEREETQQKVQDLETRNAELE- 272
QLEA + + + E+Q L+++ R+A E AER Q + + R AE+E
Sbjct: 1436 RLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVEL 1495
Query: 273 ---------------HQLRAMER-SLEEARAERERARAEVGRAAQL 302
L+A+E L+ AER +AEV RA Q+
Sbjct: 1496 ASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQV 1541
Score = 41.6 bits (96), Expect = 0.001
Identities = 42/152 (27%), Positives = 66/152 (43%), Gaps = 17/152 (11%)
Query: 173 AAAQWRQQLEAQRAEAERLRQRVAE-------LEAQAASEVTPTGEKEGLGQGQSLEQ-L 224
AA + ++L+A+ EA RLR+R + L +AA + EK Q EQ L
Sbjct: 1984 AALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQEL 2043
Query: 225 EALVQTKDQEIQTLKSQTGGPREALEAAE-------REETQ--QKVQDLETRNAELEHQL 275
+ +Q + + L+ + R A E AE RE Q ++V++ E E Q
Sbjct: 2044 QQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQA 2103
Query: 276 RAMERSLEEARAERERARAEVGRAAQLLDVSL 307
+A ++ A R+ A E R AQ +L
Sbjct: 2104 QARAQAQAAAEKLRKEAEQEAARRAQAEQAAL 2135
Score = 41.6 bits (96), Expect = 0.001
Identities = 43/217 (19%), Positives = 88/217 (40%), Gaps = 24/217 (11%)
Query: 131 ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAER 190
E ERLK+ E + Q +A L+ + A +A AA + +Q +A+ + ++
Sbjct: 2091 EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2150
Query: 191 LRQRVAELEAQAASEVTP-----------------------TGEKEGLGQGQSLEQLEAL 227
++ +AQ E+T E Q +E+
Sbjct: 2151 FAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2210
Query: 228 VQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARA 287
V+ + +E+ LK++ AL +++ TQ+ +Q+ + ++ + + + +EA
Sbjct: 2211 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2270
Query: 288 ERERARAEVGRAAQLLDVSLFELSELREGLARL-AEA 323
R+ A ++ + L + L E + + RL AEA
Sbjct: 2271 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEA 2307
Score = 38.5 bits (88), Expect = 0.008
Identities = 55/219 (25%), Positives = 93/219 (42%), Gaps = 36/219 (16%)
Query: 115 EEKLFRSQSADAPGPTERERLKKMLSEGSVG-EVQWEAEFFALQDSNNKL---------- 163
EE+L R Q A +R+ L+ L++ EV ++ A ++S +
Sbjct: 1711 EEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAE 1770
Query: 164 AGALREANAAAAQWRQQLEA-----QRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQG 218
AG RE AA+ R E Q AE + RQR AE E A ++ GE L
Sbjct: 1771 AGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR-AEAERVLAEKLAAIGEATRLKTE 1829
Query: 219 QSL---------EQLEALVQTKDQEIQTLKSQTGGPREALE--------AAEREETQQK- 260
+ E+L L + + + + L+ Q + +E A++ E +QK
Sbjct: 1830 AEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKG 1889
Query: 261 -VQDLETRNAELEHQLRAMERSLEEARAERERARAEVGR 298
V+D + ++E ++ A++ S E+A A + E+GR
Sbjct: 1890 LVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGR 1928
Score = 38.5 bits (88), Expect = 0.008
Identities = 57/231 (24%), Positives = 95/231 (41%), Gaps = 50/231 (21%)
Query: 135 LKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQ---QLEAQRAEAE-- 189
LK + + G+ + E E ++ + + +A AA+ RQ + E +R EAE
Sbjct: 1908 LKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEER 1967
Query: 190 ------------RLRQRVAE------LEAQAASEVTPTGEKEG-----LGQGQSLEQLEA 226
R R+ E + + A + E+E L Q + ++L+A
Sbjct: 1968 VQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQA 2027
Query: 227 -------LVQTKDQEI-------QTLKSQTGGPREALEAAEREETQQKVQDLETRNAELE 272
VQ K+QE+ Q++ Q G EA A E + +VQ E A+
Sbjct: 2028 EEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ-AEREAAQSR 2086
Query: 273 HQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEA 323
Q+ ER L+++ E+ +ARA+ AA+ L E + AR A+A
Sbjct: 2087 RQVEEAER-LKQSAEEQAQARAQAQAAAEKL------RKEAEQEAARRAQA 2130
Score = 28.5 bits (62), Expect = 8.5
Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 7/50 (14%)
Query: 255 EETQQKVQ------DLETRNAELEHQLRAMERSLEEARAERERARAEVGR 298
EE Q +V DL + A+L R + +S+EE RA+ ERAR++ G+
Sbjct: 511 EENQHRVDGAEWGVDLPSVEAQLGSH-RGLHQSIEEFRAKIERARSDEGQ 559
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 51.6 bits (122), Expect = 9e-07
Identities = 61/244 (25%), Positives = 104/244 (42%), Gaps = 38/244 (15%)
Query: 114 GEEKLFRSQSADAPGPT-----ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALR 168
GE + R+++ +A E ERL++ + + S + Q E E + + + A +
Sbjct: 1459 GELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQ 1518
Query: 169 EANAAAAQWRQQLEA-----QRAEAERLRQ-----------RVAELEAQAASEVTPTGEK 212
A A + R Q E ++AE ER RQ AEL+++ AS T +
Sbjct: 1519 RALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQL 1578
Query: 213 EGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELE 272
E +SL++ V +E + Q A E AERE + +++ E L+
Sbjct: 1579 E-----RSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQ 1633
Query: 273 HQLRAMERSLEEARAERERARAE------------VGRAAQLLDVSLFELSELREGLARL 320
+ A ++SL +A AE+++ AE R +L + L + +L EG A+
Sbjct: 1634 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1693
Query: 321 AEAA 324
AA
Sbjct: 1694 RLAA 1697
Score = 47.0 bits (110), Expect = 2e-05
Identities = 43/137 (31%), Positives = 65/137 (47%), Gaps = 5/137 (3%)
Query: 164 AGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPT-GEKEGLGQGQSL- 221
A L A AA+ RQ E A+ L +++ + + QA E T E E L Q + L
Sbjct: 2266 AARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA 2325
Query: 222 -EQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMER 280
EQ L + K+Q Q L +T G + LE AER+ + + E + RA R
Sbjct: 2326 QEQARRLQEDKEQMAQQLAEETQGFQRTLE-AERQRQLEMSAEAERLKLRVAEMSRAQAR 2384
Query: 281 SLEEARAERERARAEVG 297
+ E+A+ R++A E+G
Sbjct: 2385 AEEDAQRFRKQAE-EIG 2400
Score = 46.6 bits (109), Expect = 3e-05
Identities = 51/193 (26%), Positives = 86/193 (44%), Gaps = 20/193 (10%)
Query: 131 ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQ---WRQQLEAQRAE 187
E ERLK ++E S + + E + + ++ L A + Q LE QR +
Sbjct: 2367 EAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQ 2426
Query: 188 ----AERLRQRVAELEAQ-------AASEVTPTGEKEGLGQGQSLEQLEALVQT----KD 232
AERLR+ +AELE + A + E + + Q Q L++ +AL Q+ KD
Sbjct: 2427 SDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKD 2486
Query: 233 QEIQTLK--SQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARAERE 290
+Q + Q E L E + QQ ++ + + ++E + + + S+EEAR +
Sbjct: 2487 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2546
Query: 291 RARAEVGRAAQLL 303
A V R + L
Sbjct: 2547 EAEEGVRRKQEEL 2559
Score = 44.7 bits (104), Expect = 1e-04
Identities = 47/172 (27%), Positives = 79/172 (45%), Gaps = 14/172 (8%)
Query: 146 EVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEA---QRAEAERLRQRVA-ELEA- 200
E + +++ + + +L +L+E + A AQ R++ E Q+AEAER R+ ELE
Sbjct: 1561 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERW 1620
Query: 201 --QAASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQ 258
+A + + E + Q +SL Q EA Q ++ E + + G E +RE +
Sbjct: 1621 QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR---GKAEEQAVRQRELAE 1677
Query: 259 QKVQDLETRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFEL 310
Q+++ Q A E+ L RAE E+ + QLL+ L L
Sbjct: 1678 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ----RQLLEEELARL 1725
Score = 43.9 bits (102), Expect = 2e-04
Identities = 52/168 (30%), Positives = 70/168 (41%), Gaps = 38/168 (22%)
Query: 162 KLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSL 221
+LA REA AAA Q RQ+LEA+ A+ AE+E AS+ E
Sbjct: 1721 ELARLQREA-AAATQKRQELEAELAKVR------AEMEVLLASKARAEEESR-------- 1765
Query: 222 EQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERS 281
T ++ Q L+++ G RE E A R L E + Q + E
Sbjct: 1766 -------STSEKSKQRLEAEAGRFRELAEEAAR---------LRALAEEAKRQRQLAEED 1809
Query: 282 LEEARAERERARAE----VGRAAQL---LDVSLFELSELREGLARLAE 322
RAE ER AE +G A +L +++L E E L RLAE
Sbjct: 1810 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAE 1857
Score = 42.7 bits (99), Expect = 4e-04
Identities = 62/226 (27%), Positives = 97/226 (42%), Gaps = 47/226 (20%)
Query: 115 EEKLFRSQSADAPGPTERERL---------KKMLSEGSV-GEVQWEAEFFALQDSNNKLA 164
EE+L Q A+ ERERL ++ L+E + Q E E LQ ++
Sbjct: 1333 EERLAEQQRAE-----ERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ---RMQ 1384
Query: 165 GALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLE-- 222
+ AA +QQ + + E ++LRQ +E E QA + E+ L + +
Sbjct: 1385 EEVVRREEAAVDAQQQKRSIQEELQQLRQS-SEAEIQAKARQAEAAERSRLRIEEEIRVV 1443
Query: 223 --QLEALVQTK---DQEIQTLKSQT----GGPREALEAAEREETQQKVQDLETRNAELE- 272
QLEA + + + E+Q L+++ R+A E AER Q + + R AE+E
Sbjct: 1444 RLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVEL 1503
Query: 273 ---------------HQLRAMER-SLEEARAERERARAEVGRAAQL 302
L+A+E L+ AER +AEV RA Q+
Sbjct: 1504 ASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQV 1549
Score = 41.6 bits (96), Expect = 0.001
Identities = 42/152 (27%), Positives = 66/152 (43%), Gaps = 17/152 (11%)
Query: 173 AAAQWRQQLEAQRAEAERLRQRVAE-------LEAQAASEVTPTGEKEGLGQGQSLEQ-L 224
AA + ++L+A+ EA RLR+R + L +AA + EK Q EQ L
Sbjct: 1992 AALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQEL 2051
Query: 225 EALVQTKDQEIQTLKSQTGGPREALEAAE-------REETQ--QKVQDLETRNAELEHQL 275
+ +Q + + L+ + R A E AE RE Q ++V++ E E Q
Sbjct: 2052 QQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQA 2111
Query: 276 RAMERSLEEARAERERARAEVGRAAQLLDVSL 307
+A ++ A R+ A E R AQ +L
Sbjct: 2112 QARAQAQAAAEKLRKEAEQEAARRAQAEQAAL 2143
Score = 41.6 bits (96), Expect = 0.001
Identities = 43/217 (19%), Positives = 88/217 (40%), Gaps = 24/217 (11%)
Query: 131 ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAER 190
E ERLK+ E + Q +A L+ + A +A AA + +Q +A+ + ++
Sbjct: 2099 EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2158
Query: 191 LRQRVAELEAQAASEVTP-----------------------TGEKEGLGQGQSLEQLEAL 227
++ +AQ E+T E Q +E+
Sbjct: 2159 FAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2218
Query: 228 VQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARA 287
V+ + +E+ LK++ AL +++ TQ+ +Q+ + ++ + + + +EA
Sbjct: 2219 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2278
Query: 288 ERERARAEVGRAAQLLDVSLFELSELREGLARL-AEA 323
R+ A ++ + L + L E + + RL AEA
Sbjct: 2279 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEA 2315
Score = 38.5 bits (88), Expect = 0.008
Identities = 55/219 (25%), Positives = 93/219 (42%), Gaps = 36/219 (16%)
Query: 115 EEKLFRSQSADAPGPTERERLKKMLSEGSVG-EVQWEAEFFALQDSNNKL---------- 163
EE+L R Q A +R+ L+ L++ EV ++ A ++S +
Sbjct: 1719 EEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAE 1778
Query: 164 AGALREANAAAAQWRQQLEA-----QRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQG 218
AG RE AA+ R E Q AE + RQR AE E A ++ GE L
Sbjct: 1779 AGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR-AEAERVLAEKLAAIGEATRLKTE 1837
Query: 219 QSL---------EQLEALVQTKDQEIQTLKSQTGGPREALE--------AAEREETQQK- 260
+ E+L L + + + + L+ Q + +E A++ E +QK
Sbjct: 1838 AEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKG 1897
Query: 261 -VQDLETRNAELEHQLRAMERSLEEARAERERARAEVGR 298
V+D + ++E ++ A++ S E+A A + E+GR
Sbjct: 1898 LVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGR 1936
Score = 38.5 bits (88), Expect = 0.008
Identities = 57/231 (24%), Positives = 95/231 (41%), Gaps = 50/231 (21%)
Query: 135 LKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQ---QLEAQRAEAE-- 189
LK + + G+ + E E ++ + + +A AA+ RQ + E +R EAE
Sbjct: 1916 LKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEER 1975
Query: 190 ------------RLRQRVAE------LEAQAASEVTPTGEKEG-----LGQGQSLEQLEA 226
R R+ E + + A + E+E L Q + ++L+A
Sbjct: 1976 VQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQA 2035
Query: 227 -------LVQTKDQEI-------QTLKSQTGGPREALEAAEREETQQKVQDLETRNAELE 272
VQ K+QE+ Q++ Q G EA A E + +VQ E A+
Sbjct: 2036 EEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ-AEREAAQSR 2094
Query: 273 HQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEA 323
Q+ ER L+++ E+ +ARA+ AA+ L E + AR A+A
Sbjct: 2095 RQVEEAER-LKQSAEEQAQARAQAQAAAEKL------RKEAEQEAARRAQA 2138
Score = 28.5 bits (62), Expect = 8.5
Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 7/50 (14%)
Query: 255 EETQQKVQ------DLETRNAELEHQLRAMERSLEEARAERERARAEVGR 298
EE Q +V DL + A+L R + +S+EE RA+ ERAR++ G+
Sbjct: 519 EENQHRVDGAEWGVDLPSVEAQLGSH-RGLHQSIEEFRAKIERARSDEGQ 567
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 51.6 bits (122), Expect = 9e-07
Identities = 61/244 (25%), Positives = 104/244 (42%), Gaps = 38/244 (15%)
Query: 114 GEEKLFRSQSADAPGPT-----ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALR 168
GE + R+++ +A E ERL++ + + S + Q E E + + + A +
Sbjct: 1500 GELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQ 1559
Query: 169 EANAAAAQWRQQLEA-----QRAEAERLRQ-----------RVAELEAQAASEVTPTGEK 212
A A + R Q E ++AE ER RQ AEL+++ AS T +
Sbjct: 1560 RALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQL 1619
Query: 213 EGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELE 272
E +SL++ V +E + Q A E AERE + +++ E L+
Sbjct: 1620 E-----RSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQ 1674
Query: 273 HQLRAMERSLEEARAERERARAE------------VGRAAQLLDVSLFELSELREGLARL 320
+ A ++SL +A AE+++ AE R +L + L + +L EG A+
Sbjct: 1675 AEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQ 1734
Query: 321 AEAA 324
AA
Sbjct: 1735 RLAA 1738
Score = 47.0 bits (110), Expect = 2e-05
Identities = 43/137 (31%), Positives = 65/137 (47%), Gaps = 5/137 (3%)
Query: 164 AGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPT-GEKEGLGQGQSL- 221
A L A AA+ RQ E A+ L +++ + + QA E T E E L Q + L
Sbjct: 2307 AARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELA 2366
Query: 222 -EQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMER 280
EQ L + K+Q Q L +T G + LE AER+ + + E + RA R
Sbjct: 2367 QEQARRLQEDKEQMAQQLAEETQGFQRTLE-AERQRQLEMSAEAERLKLRVAEMSRAQAR 2425
Query: 281 SLEEARAERERARAEVG 297
+ E+A+ R++A E+G
Sbjct: 2426 AEEDAQRFRKQAE-EIG 2441
Score = 46.6 bits (109), Expect = 3e-05
Identities = 51/193 (26%), Positives = 86/193 (44%), Gaps = 20/193 (10%)
Query: 131 ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQ---WRQQLEAQRAE 187
E ERLK ++E S + + E + + ++ L A + Q LE QR +
Sbjct: 2408 EAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQ 2467
Query: 188 ----AERLRQRVAELEAQ-------AASEVTPTGEKEGLGQGQSLEQLEALVQT----KD 232
AERLR+ +AELE + A + E + + Q Q L++ +AL Q+ KD
Sbjct: 2468 SDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKD 2527
Query: 233 QEIQTLK--SQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARAERE 290
+Q + Q E L E + QQ ++ + + ++E + + + S+EEAR +
Sbjct: 2528 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2587
Query: 291 RARAEVGRAAQLL 303
A V R + L
Sbjct: 2588 EAEEGVRRKQEEL 2600
Score = 44.7 bits (104), Expect = 1e-04
Identities = 47/172 (27%), Positives = 79/172 (45%), Gaps = 14/172 (8%)
Query: 146 EVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEA---QRAEAERLRQRVA-ELEA- 200
E + +++ + + +L +L+E + A AQ R++ E Q+AEAER R+ ELE
Sbjct: 1602 EAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERW 1661
Query: 201 --QAASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQ 258
+A + + E + Q +SL Q EA Q ++ E + + G E +RE +
Sbjct: 1662 QLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRR---GKAEEQAVRQRELAE 1718
Query: 259 QKVQDLETRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFEL 310
Q+++ Q A E+ L RAE E+ + QLL+ L L
Sbjct: 1719 QELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQ----RQLLEEELARL 1766
Score = 43.9 bits (102), Expect = 2e-04
Identities = 52/168 (30%), Positives = 70/168 (41%), Gaps = 38/168 (22%)
Query: 162 KLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSL 221
+LA REA AAA Q RQ+LEA+ A+ AE+E AS+ E
Sbjct: 1762 ELARLQREA-AAATQKRQELEAELAKVR------AEMEVLLASKARAEEESR-------- 1806
Query: 222 EQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERS 281
T ++ Q L+++ G RE E A R L E + Q + E
Sbjct: 1807 -------STSEKSKQRLEAEAGRFRELAEEAAR---------LRALAEEAKRQRQLAEED 1850
Query: 282 LEEARAERERARAE----VGRAAQL---LDVSLFELSELREGLARLAE 322
RAE ER AE +G A +L +++L E E L RLAE
Sbjct: 1851 AARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAE 1898
Score = 42.7 bits (99), Expect = 4e-04
Identities = 62/226 (27%), Positives = 97/226 (42%), Gaps = 47/226 (20%)
Query: 115 EEKLFRSQSADAPGPTERERL---------KKMLSEGSV-GEVQWEAEFFALQDSNNKLA 164
EE+L Q A+ ERERL ++ L+E + Q E E LQ ++
Sbjct: 1374 EERLAEQQRAE-----ERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQ---RMQ 1425
Query: 165 GALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLE-- 222
+ AA +QQ + + E ++LRQ +E E QA + E+ L + +
Sbjct: 1426 EEVVRREEAAVDAQQQKRSIQEELQQLRQS-SEAEIQAKARQAEAAERSRLRIEEEIRVV 1484
Query: 223 --QLEALVQTK---DQEIQTLKSQT----GGPREALEAAEREETQQKVQDLETRNAELE- 272
QLEA + + + E+Q L+++ R+A E AER Q + + R AE+E
Sbjct: 1485 RLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVEL 1544
Query: 273 ---------------HQLRAMER-SLEEARAERERARAEVGRAAQL 302
L+A+E L+ AER +AEV RA Q+
Sbjct: 1545 ASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQV 1590
Score = 41.6 bits (96), Expect = 0.001
Identities = 42/152 (27%), Positives = 66/152 (43%), Gaps = 17/152 (11%)
Query: 173 AAAQWRQQLEAQRAEAERLRQRVAE-------LEAQAASEVTPTGEKEGLGQGQSLEQ-L 224
AA + ++L+A+ EA RLR+R + L +AA + EK Q EQ L
Sbjct: 2033 AALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQEL 2092
Query: 225 EALVQTKDQEIQTLKSQTGGPREALEAAE-------REETQ--QKVQDLETRNAELEHQL 275
+ +Q + + L+ + R A E AE RE Q ++V++ E E Q
Sbjct: 2093 QQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQA 2152
Query: 276 RAMERSLEEARAERERARAEVGRAAQLLDVSL 307
+A ++ A R+ A E R AQ +L
Sbjct: 2153 QARAQAQAAAEKLRKEAEQEAARRAQAEQAAL 2184
Score = 41.6 bits (96), Expect = 0.001
Identities = 43/217 (19%), Positives = 88/217 (40%), Gaps = 24/217 (11%)
Query: 131 ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAER 190
E ERLK+ E + Q +A L+ + A +A AA + +Q +A+ + ++
Sbjct: 2140 EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2199
Query: 191 LRQRVAELEAQAASEVTP-----------------------TGEKEGLGQGQSLEQLEAL 227
++ +AQ E+T E Q +E+
Sbjct: 2200 FAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFS 2259
Query: 228 VQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARA 287
V+ + +E+ LK++ AL +++ TQ+ +Q+ + ++ + + + +EA
Sbjct: 2260 VRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAAR 2319
Query: 288 ERERARAEVGRAAQLLDVSLFELSELREGLARL-AEA 323
R+ A ++ + L + L E + + RL AEA
Sbjct: 2320 LRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEA 2356
Score = 38.5 bits (88), Expect = 0.008
Identities = 55/219 (25%), Positives = 93/219 (42%), Gaps = 36/219 (16%)
Query: 115 EEKLFRSQSADAPGPTERERLKKMLSEGSVG-EVQWEAEFFALQDSNNKL---------- 163
EE+L R Q A +R+ L+ L++ EV ++ A ++S +
Sbjct: 1760 EEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAE 1819
Query: 164 AGALREANAAAAQWRQQLEA-----QRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQG 218
AG RE AA+ R E Q AE + RQR AE E A ++ GE L
Sbjct: 1820 AGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQR-AEAERVLAEKLAAIGEATRLKTE 1878
Query: 219 QSL---------EQLEALVQTKDQEIQTLKSQTGGPREALE--------AAEREETQQK- 260
+ E+L L + + + + L+ Q + +E A++ E +QK
Sbjct: 1879 AEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKG 1938
Query: 261 -VQDLETRNAELEHQLRAMERSLEEARAERERARAEVGR 298
V+D + ++E ++ A++ S E+A A + E+GR
Sbjct: 1939 LVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGR 1977
Score = 38.5 bits (88), Expect = 0.008
Identities = 57/231 (24%), Positives = 95/231 (41%), Gaps = 50/231 (21%)
Query: 135 LKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQ---QLEAQRAEAE-- 189
LK + + G+ + E E ++ + + +A AA+ RQ + E +R EAE
Sbjct: 1957 LKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEER 2016
Query: 190 ------------RLRQRVAE------LEAQAASEVTPTGEKEG-----LGQGQSLEQLEA 226
R R+ E + + A + E+E L Q + ++L+A
Sbjct: 2017 VQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQA 2076
Query: 227 -------LVQTKDQEI-------QTLKSQTGGPREALEAAEREETQQKVQDLETRNAELE 272
VQ K+QE+ Q++ Q G EA A E + +VQ E A+
Sbjct: 2077 EEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQ-AEREAAQSR 2135
Query: 273 HQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEA 323
Q+ ER L+++ E+ +ARA+ AA+ L E + AR A+A
Sbjct: 2136 RQVEEAER-LKQSAEEQAQARAQAQAAAEKL------RKEAEQEAARRAQA 2179
Score = 28.5 bits (62), Expect = 8.5
Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 7/50 (14%)
Query: 255 EETQQKVQ------DLETRNAELEHQLRAMERSLEEARAERERARAEVGR 298
EE Q +V DL + A+L R + +S+EE RA+ ERAR++ G+
Sbjct: 560 EENQHRVDGAEWGVDLPSVEAQLGSH-RGLHQSIEEFRAKIERARSDEGQ 608
>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
Length = 1476
Score = 51.6 bits (122), Expect = 9e-07
Identities = 63/241 (26%), Positives = 107/241 (44%), Gaps = 48/241 (19%)
Query: 126 APGPTERERLKKMLSE-----GSVGEVQWEAEFFALQDSNN---KLAGALREANAAAAQW 177
A G E+E L++ +++ ++G+ + EA+ L+ N +L+ L +A A A+
Sbjct: 721 ASGVAEQEALREEVAQLRRKAEALGD-ELEAQARKLEAQNTEAARLSKELAQARRAEAEA 779
Query: 178 RQQLEAQRAEAERLRQRV---------AELEAQAASEVTPTGEKEGLGQGQSLEQLEALV 228
++ EAQ E RLR+ V A E +A E +E + +L A
Sbjct: 780 HREAEAQAWEQARLREAVEAAGQELESASQEREALVEALAAAGRERRQWEREGSRLRAQS 839
Query: 229 QTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLE-----TRNAELEHQLRAMERSLE 283
+ ++ +Q L+S+ R+ LE AERE +++ E R EL +L ++R LE
Sbjct: 840 EAAEERMQVLESEG---RQHLEEAERERREKEALQAELEKAVVRGKELGARLEHLQRELE 896
Query: 284 EARAER------------------ERARAEVGRAAQLLDVSLFELS----ELREGLARLA 321
+A ER +R AE+ AA + +L EL +L E L +L
Sbjct: 897 QAALERQEFLREKESQHQRYQGLEQRLEAELQAAATSKEEALMELKTRALQLEEELFQLR 956
Query: 322 E 322
+
Sbjct: 957 Q 957
Score = 45.1 bits (105), Expect = 9e-05
Identities = 56/237 (23%), Positives = 99/237 (41%), Gaps = 25/237 (10%)
Query: 84 RANTVYGLGFASEQHLTQVPPSPLVSANGPGEEKLFRSQSADAPGPTERERLKKMLSEGS 143
R+N + A+ Q Q L S G +E L +SQ A +E ++ +E S
Sbjct: 985 RSNAMLVAEKAALQGQLQHLEGQLGSLQGRAQELLLQSQRA-------QEHSSRLQAEKS 1037
Query: 144 VGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAA 203
V E+Q + L+ ++ A + Q + L +A A+ R++ AELE
Sbjct: 1038 VLEIQGQELHRKLEVLEEEVRAARQSQEETRGQQQALLRDHKALAQLQRRQEAELEGLLV 1097
Query: 204 SEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQD 263
++ ++LE +Q + +++Q ++ EA E A E ++ +QD
Sbjct: 1098 R------HRDLKANMRALELAHRELQGRHEQLQAQRASV----EAQEVALLAERERLMQD 1147
Query: 264 LETRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARL 320
H+ R +E L ++E +RA+ + ++ E ELR LARL
Sbjct: 1148 --------GHRQRGLEEELRRLQSEHDRAQMLLAELSRERGELQGERGELRGRLARL 1196
Score = 43.9 bits (102), Expect = 2e-04
Identities = 49/181 (27%), Positives = 82/181 (45%), Gaps = 26/181 (14%)
Query: 140 SEGSVGEVQWE--------AEFFALQDS-NNKLAGALREANAAAAQWRQQ---LEAQRAE 187
SEG++ WE A A Q++ ++A R+A A + Q LEAQ E
Sbjct: 702 SEGALEVQVWEGPIPGESLASGVAEQEALREEVAQLRRKAEALGDELEAQARKLEAQNTE 761
Query: 188 AERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPRE 247
A RL + +A+ A +E Q +L V+ QE+++ + E
Sbjct: 762 AARLSKELAQARRAEAE-----AHREAEAQAWEQARLREAVEAAGQELESASQEREALVE 816
Query: 248 ALEAA--EREETQQKVQDLETRNAELEHQLRAME----RSLEEA---RAERERARAEVGR 298
AL AA ER + +++ L ++ E +++ +E + LEEA R E+E +AE+ +
Sbjct: 817 ALAAAGRERRQWEREGSRLRAQSEAAEERMQVLESEGRQHLEEAERERREKEALQAELEK 876
Query: 299 A 299
A
Sbjct: 877 A 877
Score = 39.3 bits (90), Expect = 0.005
Identities = 46/169 (27%), Positives = 71/169 (42%), Gaps = 16/169 (9%)
Query: 146 EVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQL-----------EAQRAEAERLRQR 194
E + EAE A S + AL E A Q ++L +RAE + + +
Sbjct: 920 EQRLEAELQAAATSKEE---ALMELKTRALQLEEELFQLRQGPAGLGPKKRAEPQLVETQ 976
Query: 195 VAELEAQAASEVTPTGEKEGL-GQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAE 253
L S EK L GQ Q LE +Q + QE+ L+SQ + AE
Sbjct: 977 NVRLIEVERSNAMLVAEKAALQGQLQHLEGQLGSLQGRAQEL-LLQSQRAQEHSSRLQAE 1035
Query: 254 REETQQKVQDLETRNAELEHQLRAMERSLEEARAERERARAEVGRAAQL 302
+ + + Q+L + LE ++RA +S EE R +++ + AQL
Sbjct: 1036 KSVLEIQGQELHRKLEVLEEEVRAARQSQEETRGQQQALLRDHKALAQL 1084
Score = 36.6 bits (83), Expect = 0.031
Identities = 47/194 (24%), Positives = 80/194 (41%), Gaps = 13/194 (6%)
Query: 110 ANGPGEEKLFRSQSADAPGPTERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALRE 169
A GP + +A A + RL++ L E + + +AE L+ +L +E
Sbjct: 249 AEGPSHHLALQLANAKA----QLRRLRQELEEKAELLLDSQAEVQGLEAEIRRLR---QE 301
Query: 170 ANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQG--QSLEQLEAL 227
A A + Q ++ E R EAE LR+R L + E+ E+ + LE+ L
Sbjct: 302 AQALSGQ-AKRAELYREEAEALRERAGRL-PRLQEELRRCRERLQAAEAYKSQLEEERVL 359
Query: 228 VQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARA 287
+ L+ Q RE A ETQ++ L TR E +L ++ +++
Sbjct: 360 SGVLEASKALLEEQLEAARE--RCARLHETQRENLLLRTRLGEAHAELDSLRHQVDQLAE 417
Query: 288 ERERARAEVGRAAQ 301
E E+ R+ +
Sbjct: 418 ENVELELELQRSLE 431
Score = 31.6 bits (70), Expect = 1.0
Identities = 32/136 (23%), Positives = 50/136 (36%), Gaps = 29/136 (21%)
Query: 211 EKEGLGQGQSLEQLEALVQTKDQ----------------------EIQTLKSQTGGPREA 248
E+EG QG L +A + DQ E+Q + G A
Sbjct: 662 EQEGPNQGLDLATGQAEAREHDQRLEGTVRDPAWQKPQQKSEGALEVQVWEGPIPGESLA 721
Query: 249 LEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARAERERARAEVGRAAQL------ 302
AE+E +++V L + L +L A R LE E R E+ +A +
Sbjct: 722 SGVAEQEALREEVAQLRRKAEALGDELEAQARKLEAQNTEAARLSKELAQARRAEAEAHR 781
Query: 303 -LDVSLFELSELREGL 317
+ +E + LRE +
Sbjct: 782 EAEAQAWEQARLREAV 797
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 51.2 bits (121), Expect = 1e-06
Identities = 51/164 (31%), Positives = 73/164 (44%), Gaps = 18/164 (10%)
Query: 156 LQDSNNKLAGALREANAAAAQWRQQ---LEAQRAEAERLRQ------RVAELEAQAASEV 206
L++ + L G R+A A R++ LE R E E RQ RVAE +A +
Sbjct: 762 LEEEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQ 821
Query: 207 TPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLET 266
PT E + L QL + ++QE++ + + EALE A RE+ + L
Sbjct: 822 LPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREK-----EALAK 876
Query: 267 RNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFEL 310
+A L QL A ER E R R E + L+ SLFE+
Sbjct: 877 EHAGLAVQLVAAEREGRTLSEEATRLRLE----KEALEGSLFEV 916
Score = 44.3 bits (103), Expect = 1e-04
Identities = 55/197 (27%), Positives = 87/197 (44%), Gaps = 14/197 (7%)
Query: 128 GPTERERLKKMLSEGSVGEVQWEAEFFAL----QDSNNKLAGALREANAAAAQWRQQLEA 183
G ERE L++ E + E+E +L +D KLA L EA A + +L
Sbjct: 1208 GAKEREALRRSNEELRSAVKKAESERISLKLANEDKEQKLA-LLEEARTAVGKEAGELRT 1266
Query: 184 QRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTG 243
E ER R A E Q + E G+ L +L+ + ++ + + +T
Sbjct: 1267 GLQEVERSRLE-ARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETL 1325
Query: 244 GPREALEAAER--EETQQKVQDLETRNAELEHQLRAMER----SLEEARAERERARAEVG 297
G R+ L E E +Q++Q + + E E + R ER SLEEAR E+ + +
Sbjct: 1326 GLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARG-TEKQQLDHA 1384
Query: 298 RAAQL-LDVSLFELSEL 313
R +L L+ + E +EL
Sbjct: 1385 RGLELKLEAARAEAAEL 1401
Score = 43.5 bits (101), Expect = 3e-04
Identities = 49/219 (22%), Positives = 92/219 (42%), Gaps = 18/219 (8%)
Query: 90 GLGFASEQHLTQVPPSPLVSANGPGEEKLFRSQSADAPGPTERERLKKMLSEGSVGEVQW 149
GLG A VP SP A G + S S P + + + ++
Sbjct: 1445 GLGRAPSPAPRPVPGSPARDAPAEGSGEGLNSPSTLECSPGSQPPSPGPATSPASPDLDP 1504
Query: 150 EAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPT 209
EA AL++ +L A RE R +L R + L +++AE+EA+ S +
Sbjct: 1505 EAVRGALREFLQELRSAQRE--------RDEL---RTQTSALNRQLAEMEAERDSATSRA 1553
Query: 210 GEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREE--TQQKVQDLETR 267
+ + +++ + E ++ D + ++++ E++ +ERE T +V LE
Sbjct: 1554 RQLQ-----KAVAESEEARRSVDGRLSGVQAELALQEESVRRSERERRATLDQVATLERS 1608
Query: 268 NAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVS 306
E +LRA + + + +A + + R ++LD S
Sbjct: 1609 LQATESELRASQEKISKMKANETKLEGDKRRLKEVLDAS 1647
Score = 42.7 bits (99), Expect = 4e-04
Identities = 45/170 (26%), Positives = 71/170 (41%), Gaps = 4/170 (2%)
Query: 155 ALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGE-KE 213
A + L L A A ++ R+Q + + + LR VA+LE Q + +E
Sbjct: 1758 ACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQLQQLRE 1817
Query: 214 GLGQGQSLEQLEA-LVQTKDQEIQTLKSQTGGPREALEA--AEREETQQKVQDLETRNAE 270
L Q Q E VQ E + L+ + G + AL AE+ E ++ LE
Sbjct: 1818 VLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSALRLEKDRVA 1877
Query: 271 LEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARL 320
L L +ER + + R AE GR + L + EL+E + + +L
Sbjct: 1878 LRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQL 1927
Score = 40.4 bits (93), Expect = 0.002
Identities = 56/201 (27%), Positives = 85/201 (42%), Gaps = 33/201 (16%)
Query: 114 GEEKLFRSQSADAPGPTERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAA 173
GE Q +A G + ++L+++L + GE LQD L L A
Sbjct: 1796 GEVADLELQRVEAEG--QLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRA 1853
Query: 174 AAQWRQQLEAQRAEAER-----------LRQRVAELEAQAASE----VTPTGEKEGLGQ- 217
AQ LEA++ E ER LR+ + ++E + V + EK L +
Sbjct: 1854 LAQ----LEAEKREVERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRT 1909
Query: 218 --GQSLEQLEALVQTKDQEIQTLK-SQTGGPREALEAAERE--ETQQKVQDLETRNAELE 272
G LE EA Q + E Q + Q+ P + A+++ E QQ+V+ L + A+ E
Sbjct: 1910 LTGAELELAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTE 1969
Query: 273 HQLRAMERSLEEARAERERAR 293
L A E RA R+R R
Sbjct: 1970 RTLEARE------RAHRQRVR 1984
Score = 39.7 bits (91), Expect = 0.004
Identities = 41/165 (24%), Positives = 73/165 (44%), Gaps = 11/165 (6%)
Query: 166 ALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQ--AASEVTPTGEKEGLGQGQSLEQ 223
AL + R + EA + LR+++++ E++ A E + G Q+ E
Sbjct: 527 ALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHED 586
Query: 224 LEALVQTKDQEIQTLKSQTGGPREALEAAER--EETQQKVQDLETRNAELEHQLRAMERS 281
+ VQ + L + +L+ A++ EE +Q+ + L+ EL Q +E
Sbjct: 587 AQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEE 646
Query: 282 LEEARAERERARAEVGRAAQLLD-------VSLFELSELREGLAR 319
E+A + R R E+ R+ + L+ V EL E+RE L+R
Sbjct: 647 QEDAVQDGARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSR 691
Score = 39.7 bits (91), Expect = 0.004
Identities = 51/194 (26%), Positives = 81/194 (41%), Gaps = 27/194 (13%)
Query: 132 RERLKKMLSEGSVGEVQWE-AEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAER 190
R RL+K EGS+ EVQ + A+ A ++ AL A E E
Sbjct: 901 RLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAK----------ETLTGELAG 950
Query: 191 LRQRVAELEAQAASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALE 250
LRQ++ + +A+ +KE + Q LVQ + + +L+ Q E L+
Sbjct: 951 LRQQIIATQEKASL------DKELMAQ--------KLVQAEREAQASLREQRAAHEEDLQ 996
Query: 251 AAEREETQQKVQDLETRNAELEHQL-RAMERSLEEARAERERARAEVGRAAQLLDVSLFE 309
+RE+ + ++LE A+L+ QL R E L AE+E E+ Q D L
Sbjct: 997 RLQREK-EAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLL 1055
Query: 310 LSELREGLARLAEA 323
++ L E+
Sbjct: 1056 AESEKQQALSLKES 1069
Score = 39.3 bits (90), Expect = 0.005
Identities = 47/170 (27%), Positives = 72/170 (42%), Gaps = 28/170 (16%)
Query: 156 LQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGL 215
L+D+ + L L EA + ++ E QR EA LR+ + E G KE
Sbjct: 1166 LEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGE------------GAKERE 1213
Query: 216 GQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLE---TRNAELE 272
+S E+L + V+ + E +LK E+ +QK+ LE T +
Sbjct: 1214 ALRRSNEELRSAVKKAESERISLK------------LANEDKEQKLALLEEARTAVGKEA 1261
Query: 273 HQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELS-ELREGLARLA 321
+LR + +E +R E R E+ R ++LD L EL E RLA
Sbjct: 1262 GELRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLA 1311
Score = 38.9 bits (89), Expect = 0.006
Identities = 59/227 (25%), Positives = 97/227 (42%), Gaps = 31/227 (13%)
Query: 115 EEKLFRSQSADAPGPTERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAA 174
+E L S+S +R L+ L +G EA+ ALQD + L + ++ A
Sbjct: 1641 KEVLDASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKA 1700
Query: 175 AQWRQQLE------AQRAEAE-RLRQRV---AELEAQAASEVTPTGEKEGLGQGQSLEQL 224
+ +E A+ E+E LR +V E AQ+++ + T +K L
Sbjct: 1701 GTLQLTVERLNGALAKVEESEGALRDKVRGLTEALAQSSASLNSTRDKN--------LHL 1752
Query: 225 EALVQTKDQEIQTLKSQTGGPREALEAAEREETQ--QKVQDLETRNAELEHQLRAMERSL 282
+ + + + Q L+ + R+AL A ++ + ++VQ L A+LE Q E L
Sbjct: 1753 QKALTACEHDRQVLQERLDAARQALSEARKQSSSLGEQVQTLRGEVADLELQRVEAEGQL 1812
Query: 283 EEARAERERARAEVGRAAQLLDVSLFE---------LSELREGLARL 320
++ R E R R E G AA L V + L L+ LA+L
Sbjct: 1813 QQLR-EVLRQRQE-GEAAALNTVQKLQDERRLLQERLGSLQRALAQL 1857
Score = 36.2 bits (82), Expect = 0.041
Identities = 44/172 (25%), Positives = 75/172 (43%), Gaps = 11/172 (6%)
Query: 151 AEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTG 210
A +LQ+ N L L AQ R + + + + +R+ + E+ T
Sbjct: 74 ASLLSLQEENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQALRLEPGELE-TQ 132
Query: 211 EKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAE 270
E GL + QS+E L + + + L++ G + + +R Q K+ + R +E
Sbjct: 133 EPRGLVR-QSVELRRQLQEEQASYRRKLQAYQEGQQRQAQLVQR--LQGKILQYKKRCSE 189
Query: 271 LEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAE 322
LE QL +ERS E E+ R +Q L+ +L L E ++ A LA+
Sbjct: 190 LEQQL--LERS-----GELEQQRLRDTEHSQDLESALIRLEEEQQRSASLAQ 234
Score = 35.8 bits (81), Expect = 0.053
Identities = 45/169 (26%), Positives = 72/169 (42%), Gaps = 27/169 (15%)
Query: 167 LREANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLEQLEA 226
+REA + A R L+A++AE + + +T +E Q SL +L A
Sbjct: 685 VREALSRATLQRDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQ-DSLSKLSA 743
Query: 227 LVQTKDQE---IQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLE 283
L ++ Q+ + L +Q + AL+ +R+ Q+ R + LE
Sbjct: 744 LNESLAQDKLDLNRLVAQLEEEKSALQGRQRQAEQEATV------------AREEQERLE 791
Query: 284 EARAERERAR---------AEVGRAA--QLLDVSLFELSELREGLARLA 321
E R E+E AR AE + A Q L E S+L+E LA+L+
Sbjct: 792 ELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLS 840
Score = 35.4 bits (80), Expect = 0.070
Identities = 44/179 (24%), Positives = 78/179 (43%), Gaps = 25/179 (13%)
Query: 158 DSNNKLAGALREANAAAAQWRQQLEAQRAEAERLRQRV---------AELEAQ---AASE 205
+++ L G LR+ + + R+ LE Q +RLR + A+ E Q +A+E
Sbjct: 543 EASQDLLGTLRKQLSDSESERRALEEQ---LQRLRDKTDGAMQAHEDAQREVQRLRSANE 599
Query: 206 VTPTGEKEGLGQGQSLEQLEALVQTKDQE-IQTLKSQTGGPREALEAAEREETQQKVQDL 264
+ + EK L + Q +A +++E +Q + + R+ LE EE + VQD
Sbjct: 600 LL-SREKSNLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLE----EEQEDAVQD- 653
Query: 265 ETRNAELEHQLRAMERSLEEARAERERARAEVGRAAQLLDVSLFELSELREGLARLAEA 323
A + +L R LE+ +R E+ + L + + L+ A +AEA
Sbjct: 654 ---GARVRRELERSHRQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEA 709
Score = 34.7 bits (78), Expect = 0.12
Identities = 42/169 (24%), Positives = 71/169 (42%), Gaps = 18/169 (10%)
Query: 132 RERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAER- 190
R+ L+ L + E + L+ ++L L + + + Q+LE R EA+R
Sbjct: 801 RQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQ 860
Query: 191 ---LRQRVAELEAQAASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPRE 247
L + E EA A KE G L E +T +E L+ + +E
Sbjct: 861 VEALERAAREKEALA---------KEHAGLAVQLVAAEREGRTLSEEATRLRLE----KE 907
Query: 248 ALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARAERERARAEV 296
ALE + E Q+++ LE R +LE + +A+ + E E R ++
Sbjct: 908 ALEGS-LFEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQI 955
Score = 34.7 bits (78), Expect = 0.12
Identities = 51/217 (23%), Positives = 85/217 (39%), Gaps = 51/217 (23%)
Query: 156 LQDSNNKLAGALREANAAAAQWRQQLEAQR--------AEAERLRQRVAELEAQA----- 202
LQ + A RE A AQ + QL+ ++ AE E L + +A L+ +
Sbjct: 995 LQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLL 1054
Query: 203 -------------ASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREAL 249
SE T EK +G SL + ++ + ++ Q+ + Q AL
Sbjct: 1055 LAESEKQQALSLKESEKTALSEKL-MGTRHSLATISLEMERQKRDAQSRQEQDRSTVNAL 1113
Query: 250 EA------AEREET-----------QQKVQDLETRN-------AELEHQLRAMERSLEEA 285
+ A+REE Q++ +DL + EL QLR +E + +
Sbjct: 1114 TSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDGL 1173
Query: 286 RAERERARAEVGRAAQLLDVSLFELSELREGLARLAE 322
R E A+ ++ + + +V E ELR L A+
Sbjct: 1174 RRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAK 1210
Score = 32.3 bits (72), Expect = 0.59
Identities = 31/102 (30%), Positives = 47/102 (46%), Gaps = 20/102 (19%)
Query: 182 EAQRAEAERLRQRVAELEAQAASEVTPTGEKEGLGQGQSLEQLEALVQTKD----QEIQT 237
E + AEA+R ++ +LEAQ L Q S QLE Q + QE++
Sbjct: 1914 ELELAEAQR---QIQQLEAQVVV----------LEQSHSPAQLEVDAQQQQLELQQEVER 1960
Query: 238 LKS---QTGGPREALEAAEREETQQKVQDLETRNAELEHQLR 276
L+S QT EA E A R+ + + + T +L+ +LR
Sbjct: 1961 LRSAQAQTERTLEARERAHRQRVRGLEEQVSTLKGQLQQELR 2002
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 50.1 bits (118), Expect = 3e-06
Identities = 47/205 (22%), Positives = 86/205 (41%), Gaps = 25/205 (12%)
Query: 134 RLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQ----------------W 177
+L++ L E F ALQ+ L+ + + +Q +
Sbjct: 2571 KLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLY 2630
Query: 178 RQQLEAQRAEAERL-------RQRVAELEAQAASEVTPTGEKEGLGQGQSLEQLEALVQT 230
QL+ + E RL ++R+AELE + +K G + + ++L+ L
Sbjct: 2631 HAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHH- 2689
Query: 231 KDQEIQTLKSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERSLEEARAERE 290
D I +++T R A A + E +QK+ + N L Q+++ RS+ + R+
Sbjct: 2690 -DAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQNSRD 2748
Query: 291 RARAEVGRAAQLLDVSLFELSELRE 315
A E+ + D SL EL++L+E
Sbjct: 2749 HANEELDELKRKYDASLKELAQLKE 2773
Score = 46.6 bits (109), Expect = 3e-05
Identities = 48/198 (24%), Positives = 85/198 (42%), Gaps = 32/198 (16%)
Query: 130 TERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEA----QR 185
TERE K +L + + + + F LQ+ + L +A A A+ + A +
Sbjct: 312 TEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHK 371
Query: 186 AEAERLRQRVAEL-----EAQAA--------SEVTPTGEKEGLGQGQSLEQLEALVQTKD 232
AE E + L E Q+A S++ ++ + Q+++QLE +Q K
Sbjct: 372 AEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKS 431
Query: 233 QEIQTL-----------KSQTGGPREALEAAEREETQQKVQDLETRNAELEHQLRAMERS 281
+EI SQT P + + T++ + L+ R ELE++ A+ S
Sbjct: 432 KEISQFLNRLPLQQHETASQTSFP-DVYNEGTQAVTEENIASLQKRVVELENEKGALLLS 490
Query: 282 ---LEEARAERERARAEV 296
LEE +AE E+ +++
Sbjct: 491 SIELEELKAENEKLSSQI 508
Score = 38.5 bits (88), Expect = 0.008
Identities = 46/198 (23%), Positives = 82/198 (41%), Gaps = 18/198 (9%)
Query: 131 ERERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQ--QLEAQRAEA 188
E L +++ E + F AL + ++L ++E + Q QLE AEA
Sbjct: 717 EISNLNQLIEEFKKNADNNSSAFTALSEERDQLLSQVKELSMVTELRAQVKQLEMNLAEA 776
Query: 189 ERLRQRVAELEAQAASEVTPTGEKEGLG------------QGQSLEQLEALVQTKDQEIQ 236
ER QR + E+Q A + T + L L+ ++ + I+
Sbjct: 777 ER--QRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQNELDDVQLQFSEQSTLIR 834
Query: 237 TLKSQTGGPR-EALEAAER-EETQQKVQDLETRNAELEHQLRAMERSLEEARAERERARA 294
+L+SQ E LE AER KV++L ++ E ++ M++ L E + + E +
Sbjct: 835 SLQSQLQNKESEVLEGAERVRHISSKVEELSQALSQKELEITKMDQLLLEKKRDVETLQQ 894
Query: 295 EVGRAAQLLDVSLFELSE 312
+ Q + F ++E
Sbjct: 895 TIEEKDQQVTEISFSMTE 912
Score = 37.7 bits (86), Expect = 0.014
Identities = 50/202 (24%), Positives = 86/202 (42%), Gaps = 15/202 (7%)
Query: 133 ERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQ-RAEAERL 191
E+ +LS G+ + ++ AL+D N+KL E +AQ QQLE Q + +++ +
Sbjct: 376 EKTSHILSLQKTGQ-ELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEI 434
Query: 192 RQRVAELEAQAASEVTPTGEKEGLGQGQS--LEQLEALVQTKDQEIQTLKSQTGGPREAL 249
Q + L Q + T + +G E+ A +Q + E++ K L
Sbjct: 435 SQFLNRLPLQQHETASQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIEL 494
Query: 250 E--AAEREETQQKVQDLETRNAELEHQLRAMERSLEEARAERERARAEVGRAA------- 300
E AE E+ ++ LE +N E E S+ + +R + E G+
Sbjct: 495 EELKAENEKLSSQITLLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTFSQ 554
Query: 301 --QLLDVSLFELSELREGLARL 320
+ L V L E+ E +E +A L
Sbjct: 555 KHKELSVLLLEMKEAQEEIAFL 576
Score = 35.0 bits (79), Expect = 0.091
Identities = 46/224 (20%), Positives = 87/224 (38%), Gaps = 40/224 (17%)
Query: 132 RERLKKMLSEGSVGEVQWEAEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAEAERL 191
++++++ L + + E +LQ+ + G + + A Q+ AQ E + +
Sbjct: 1478 KQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTV 1537
Query: 192 RQRVAELEAQAASEVTPTGEKEGLGQGQSLEQ--------LEALVQTKDQ---EIQTLKS 240
R+A L+ + +T L + QSL LE L + K++ EI++LKS
Sbjct: 1538 LGRLALLQEERDKLITEMDRS--LLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKS 1595
Query: 241 QTGGPREALE--------------------AAEREETQQKVQDLETRNAELEHQLRAME- 279
+ + E E Q V+ + EL +LR+ E
Sbjct: 1596 SKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTEA 1655
Query: 280 ------RSLEEARAERERARAEVGRAAQLLDVSLFELSELREGL 317
+ L+EA E E + ++ + A+ + EL E + L
Sbjct: 1656 NKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRL 1699
Score = 33.1 bits (74), Expect = 0.35
Identities = 45/210 (21%), Positives = 86/210 (40%), Gaps = 43/210 (20%)
Query: 155 ALQDSNNKLAGAL---REANAAAAQWRQQLEAQRAEAERLRQRVAELEAQAASEVTP--- 208
A Q KL AL +EA +++L R ERL + +A++E+Q +++
Sbjct: 1477 AKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDT 1536
Query: 209 ----------------TGEKEGLGQGQSLEQ--------LEALVQTKD---QEIQTLKSQ 241
T L + QSL LE L + K+ +EI++LKS
Sbjct: 1537 VLGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSS 1596
Query: 242 TGGPREALEAAEREETQQKVQDLETRNAE--------LEHQLRAMERSLEEARAERERAR 293
E+ E E+ + QK ++ ++ E ++H + A+ + +E +
Sbjct: 1597 K--IAESTEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQEKQELYGKLRSTE 1654
Query: 294 AEVGRAAQLLDVSLFELSELREGLARLAEA 323
A + L + E+ E++E + + A++
Sbjct: 1655 ANKKETEKQLQEAEQEMEEMKEKMRKFAKS 1684
Score = 32.3 bits (72), Expect = 0.59
Identities = 37/166 (22%), Positives = 72/166 (43%), Gaps = 16/166 (9%)
Query: 129 PTERERLKKMLSEGSVGEVQWE-AEFFALQDSNNKLAGALREANAAAAQWRQQLEAQRAE 187
P E L + E + E Q +E +L D+ +L ++ + + + + + E
Sbjct: 626 PNEESSLPAVEKEQASTEHQSRTSEEISLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDE 685
Query: 188 AERLRQRVAELEA--QAASEVTPTGEKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGP 245
ERL+ ++ ELE A E+ ++L++ + +Q I+ K
Sbjct: 686 LERLKSQILELELNFHKAQEI----------YEKNLDEKAKEISNLNQLIEEFKKNADNN 735
Query: 246 REALEA--AEREETQQKVQDLETRNAELEHQLRAMERSLEEARAER 289
A A ER++ +V++L + EL Q++ +E +L EA +R
Sbjct: 736 SSAFTALSEERDQLLSQVKEL-SMVTELRAQVKQLEMNLAEAERQR 780
Score = 31.6 bits (70), Expect = 1.0
Identities = 40/176 (22%), Positives = 70/176 (39%), Gaps = 40/176 (22%)
Query: 158 DSNNKLAGALREANAAAAQWRQQL-------EAQRAEAERLRQRVAELEAQAASEVTPTG 210
D +L L E N + + Q + E +E + L++ V+ELE + V
Sbjct: 1921 DLEERLMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKT 1980
Query: 211 EKEGLGQGQSLEQLEALVQTKDQEIQTLKSQTGGPREALEAAER-EETQQKVQDLETRNA 269
+ E + + LE+ IQ + + G A E E +E QQ+V+ L+
Sbjct: 1981 KVESEIRKEYLEK-----------IQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCI 2029
Query: 270 ELEHQLRAMER---------------------SLEEARAERERARAEVGRAAQLLD 304
+ ++ A+ER +L +A R++A+AE+ LLD
Sbjct: 2030 RYQEKISALERTVKALEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLD 2085
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.125 0.339
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,184,347
Number of Sequences: 37866
Number of extensions: 484790
Number of successful extensions: 5754
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 254
Number of HSP's successfully gapped in prelim test: 578
Number of HSP's that attempted gapping in prelim test: 3175
Number of HSP's gapped (non-prelim): 2318
length of query: 325
length of database: 18,247,518
effective HSP length: 102
effective length of query: 223
effective length of database: 14,385,186
effective search space: 3207896478
effective search space used: 3207896478
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.