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Search of human proteins with 115527117
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|115527117 homogentisate 1,2-dioxygenase [Homo sapiens]
(445 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|115527117 homogentisate 1,2-dioxygenase [Homo sapiens] 943 0.0
gi|62945408 cancer/testis antigen family 45, member A4 [Homo sap... 34 0.23
gi|124486720 cancer/testis antigen CT45 [Homo sapiens] 34 0.23
gi|62945410 cancer/testis antigen family 45, member A6 [Homo sap... 34 0.23
gi|62899069 cancer/testis antigen family 45, member A1 [Homo sap... 34 0.31
gi|88758613 CD93 antigen precursor [Homo sapiens] 34 0.31
gi|62945406 cancer/testis antigen family 45, member A3 [Homo sap... 34 0.31
gi|23943872 small ArfGAP2 [Homo sapiens] 32 1.5
gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo sa... 30 3.4
gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo sap... 30 3.4
gi|14196471 protocadherin gamma subfamily A, 5 isoform 2 precurs... 30 3.4
gi|11056024 protocadherin gamma subfamily A, 5 isoform 1 precurs... 30 3.4
gi|190885497 Rho guanine nucleotide exchange factor 3 isoform 2 ... 29 9.9
gi|190885495 Rho guanine nucleotide exchange factor 3 isoform 1 ... 29 9.9
gi|9506401 Rho guanine nucleotide exchange factor 3 isoform 3 [H... 29 9.9
>gi|115527117 homogentisate 1,2-dioxygenase [Homo sapiens]
Length = 445
Score = 943 bits (2438), Expect = 0.0
Identities = 445/445 (100%), Positives = 445/445 (100%)
Query: 1 MAELKYISGFGNECSSEDPRCPGSLPEGQNNPQVCPYNLYAEQLSGSAFTCPRSTNKRSW 60
MAELKYISGFGNECSSEDPRCPGSLPEGQNNPQVCPYNLYAEQLSGSAFTCPRSTNKRSW
Sbjct: 1 MAELKYISGFGNECSSEDPRCPGSLPEGQNNPQVCPYNLYAEQLSGSAFTCPRSTNKRSW 60
Query: 61 LYRILPSVSHKPFESIDEGQVTHNWDEVDPDPNQLRWKPFEIPKASQKKVDFVSGLHTLC 120
LYRILPSVSHKPFESIDEGQVTHNWDEVDPDPNQLRWKPFEIPKASQKKVDFVSGLHTLC
Sbjct: 61 LYRILPSVSHKPFESIDEGQVTHNWDEVDPDPNQLRWKPFEIPKASQKKVDFVSGLHTLC 120
Query: 121 GAGDIKSNNGLAIHIFLCNTSMENRCFYNSDGDFLIVPQKGNLLIYTEFGKMLVQPNEIC 180
GAGDIKSNNGLAIHIFLCNTSMENRCFYNSDGDFLIVPQKGNLLIYTEFGKMLVQPNEIC
Sbjct: 121 GAGDIKSNNGLAIHIFLCNTSMENRCFYNSDGDFLIVPQKGNLLIYTEFGKMLVQPNEIC 180
Query: 181 VIQRGMRFSIDVFEETRGYILEVYGVHFELPDLGPIGANGLANPRDFLIPIAWYEDRQVP 240
VIQRGMRFSIDVFEETRGYILEVYGVHFELPDLGPIGANGLANPRDFLIPIAWYEDRQVP
Sbjct: 181 VIQRGMRFSIDVFEETRGYILEVYGVHFELPDLGPIGANGLANPRDFLIPIAWYEDRQVP 240
Query: 241 GGYTVINKYQGKLFAAKQDVSPFNVVAWHGNYTPYKYNLKNFMVINSVAFDHADPSIFTV 300
GGYTVINKYQGKLFAAKQDVSPFNVVAWHGNYTPYKYNLKNFMVINSVAFDHADPSIFTV
Sbjct: 241 GGYTVINKYQGKLFAAKQDVSPFNVVAWHGNYTPYKYNLKNFMVINSVAFDHADPSIFTV 300
Query: 301 LTAKSVRPGVAIADFVIFPPRWGVADKTFRPPYYHRNCMSEFMGLIRGHYEAKQGGFLPG 360
LTAKSVRPGVAIADFVIFPPRWGVADKTFRPPYYHRNCMSEFMGLIRGHYEAKQGGFLPG
Sbjct: 301 LTAKSVRPGVAIADFVIFPPRWGVADKTFRPPYYHRNCMSEFMGLIRGHYEAKQGGFLPG 360
Query: 361 GGSLHSTMTPHGPDADCFEKASKVKLAPERIADGTMAFMFESSLSLAVTKWGLKASRCLD 420
GGSLHSTMTPHGPDADCFEKASKVKLAPERIADGTMAFMFESSLSLAVTKWGLKASRCLD
Sbjct: 361 GGSLHSTMTPHGPDADCFEKASKVKLAPERIADGTMAFMFESSLSLAVTKWGLKASRCLD 420
Query: 421 ENYHKCWEPLKSHFTPNSRNPAEPN 445
ENYHKCWEPLKSHFTPNSRNPAEPN
Sbjct: 421 ENYHKCWEPLKSHFTPNSRNPAEPN 445
>gi|62945408 cancer/testis antigen family 45, member A4 [Homo
sapiens]
Length = 189
Score = 34.3 bits (77), Expect = 0.23
Identities = 27/101 (26%), Positives = 43/101 (42%), Gaps = 16/101 (15%)
Query: 331 PPYYHRNCMSEFMGLIRGHYEAKQGGFLPGGGSLHSTMTPHGPDADCFEKASKVKLAPER 390
PP + + +F G + K G P GG++ S+ + G D +C E AS K E
Sbjct: 65 PPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFS--GDDLECRETASSPKSQQEI 122
Query: 391 IADGTMAFMFESSLSLAVTKWGLKASRCLDENYHKCWEPLK 431
AD + + +K RC+ + Y K +E L+
Sbjct: 123 NAD--------------IKRKLVKELRCVGQKYEKIFEMLE 149
>gi|124486720 cancer/testis antigen CT45 [Homo sapiens]
Length = 189
Score = 34.3 bits (77), Expect = 0.23
Identities = 27/101 (26%), Positives = 43/101 (42%), Gaps = 16/101 (15%)
Query: 331 PPYYHRNCMSEFMGLIRGHYEAKQGGFLPGGGSLHSTMTPHGPDADCFEKASKVKLAPER 390
PP + + +F G + K G P GG++ S+ + G D +C E AS K E
Sbjct: 65 PPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFS--GDDLECRETASSPKSQQEI 122
Query: 391 IADGTMAFMFESSLSLAVTKWGLKASRCLDENYHKCWEPLK 431
AD + + +K RC+ + Y K +E L+
Sbjct: 123 NAD--------------IKRKLVKELRCVGQKYEKIFEMLE 149
>gi|62945410 cancer/testis antigen family 45, member A6 [Homo
sapiens]
Length = 189
Score = 34.3 bits (77), Expect = 0.23
Identities = 27/101 (26%), Positives = 43/101 (42%), Gaps = 16/101 (15%)
Query: 331 PPYYHRNCMSEFMGLIRGHYEAKQGGFLPGGGSLHSTMTPHGPDADCFEKASKVKLAPER 390
PP + + +F G + K G P GG++ S+ + G D +C E AS K E
Sbjct: 65 PPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFS--GDDLECRETASSPKSQQEI 122
Query: 391 IADGTMAFMFESSLSLAVTKWGLKASRCLDENYHKCWEPLK 431
AD + + +K RC+ + Y K +E L+
Sbjct: 123 NAD--------------IKRKLVKELRCVGQKYEKIFEMLE 149
>gi|62899069 cancer/testis antigen family 45, member A1 [Homo
sapiens]
Length = 189
Score = 33.9 bits (76), Expect = 0.31
Identities = 27/101 (26%), Positives = 43/101 (42%), Gaps = 16/101 (15%)
Query: 331 PPYYHRNCMSEFMGLIRGHYEAKQGGFLPGGGSLHSTMTPHGPDADCFEKASKVKLAPER 390
PP + + +F G + K G P GG++ S+ + G D +C E AS K E
Sbjct: 65 PPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFS--GDDLECRETASSPKSQREI 122
Query: 391 IADGTMAFMFESSLSLAVTKWGLKASRCLDENYHKCWEPLK 431
AD + + +K RC+ + Y K +E L+
Sbjct: 123 NAD--------------IKRKLVKELRCVGQKYEKIFEMLE 149
>gi|88758613 CD93 antigen precursor [Homo sapiens]
Length = 652
Score = 33.9 bits (76), Expect = 0.31
Identities = 20/71 (28%), Positives = 30/71 (42%), Gaps = 4/71 (5%)
Query: 92 PNQLRWK-PFEIPKASQKKVDFVSGLHTLCGAGDIKSNNGLAIHIFLCNTSMENRCFYNS 150
P Q+ + PF+ +S + V F S + CG GD H FLC + + S
Sbjct: 196 PGQVTYTTPFQTTSSSLEAVPFASAANVACGEGDKDETQS---HYFLCKEKAPDVFDWGS 252
Query: 151 DGDFLIVPQKG 161
G + P+ G
Sbjct: 253 SGPLCVSPKYG 263
>gi|62945406 cancer/testis antigen family 45, member A3 [Homo
sapiens]
Length = 189
Score = 33.9 bits (76), Expect = 0.31
Identities = 27/101 (26%), Positives = 43/101 (42%), Gaps = 16/101 (15%)
Query: 331 PPYYHRNCMSEFMGLIRGHYEAKQGGFLPGGGSLHSTMTPHGPDADCFEKASKVKLAPER 390
PP + + +F G + K G P GG++ S+ + G D +C E AS K E
Sbjct: 65 PPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFS--GDDLECRETASSPKSQREI 122
Query: 391 IADGTMAFMFESSLSLAVTKWGLKASRCLDENYHKCWEPLK 431
AD + + +K RC+ + Y K +E L+
Sbjct: 123 NAD--------------IKRKLVKELRCVGQKYEKIFEMLE 149
>gi|23943872 small ArfGAP2 [Homo sapiens]
Length = 429
Score = 31.6 bits (70), Expect = 1.5
Identities = 25/114 (21%), Positives = 46/114 (40%), Gaps = 2/114 (1%)
Query: 257 KQDVSPFNVVAWHGNYTPYKYNLKNFMVINSVAFDHADPSIFTVLTAKSVRPGV--AIAD 314
K+ +S ++++ +G+ TP FM +A+ A PS V S+ +
Sbjct: 260 KKQLSKDSILSLYGSQTPQMPTQAMFMAPAQMAYPTAYPSFPGVTPPNSIMGSMMPPPVG 319
Query: 315 FVIFPPRWGVADKTFRPPYYHRNCMSEFMGLIRGHYEAKQGGFLPGGGSLHSTM 368
V P G+ P Y + MG+ G +Q G++ G ++ T+
Sbjct: 320 MVAQPGASGMVAPMAMPAGYMGGMQASMMGVPNGMMTTQQAGYMAGMAAMPQTV 373
>gi|29171753 PTPRF interacting protein alpha 1 isoform a [Homo
sapiens]
Length = 1185
Score = 30.4 bits (67), Expect = 3.4
Identities = 18/52 (34%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Query: 359 PGGGSLHSTMTPHGPDADCFEKASKVKLAPERIADGTMAFMFESSLSLAVTK 410
PGGG H + +P PDAD + V + ER D + + E+ +LA+T+
Sbjct: 16 PGGGGGHGSGSPSQPDADSHFEQLMVSMLEER--DRLLDTLRETQETLALTQ 65
>gi|4505983 PTPRF interacting protein alpha 1 isoform b [Homo
sapiens]
Length = 1202
Score = 30.4 bits (67), Expect = 3.4
Identities = 18/52 (34%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Query: 359 PGGGSLHSTMTPHGPDADCFEKASKVKLAPERIADGTMAFMFESSLSLAVTK 410
PGGG H + +P PDAD + V + ER D + + E+ +LA+T+
Sbjct: 16 PGGGGGHGSGSPSQPDADSHFEQLMVSMLEER--DRLLDTLRETQETLALTQ 65
>gi|14196471 protocadherin gamma subfamily A, 5 isoform 2 precursor
[Homo sapiens]
Length = 813
Score = 30.4 bits (67), Expect = 3.4
Identities = 26/95 (27%), Positives = 41/95 (43%), Gaps = 9/95 (9%)
Query: 41 AEQLSGSAFTCPRSTNKRSWLYRILPSVSHKPFE----SIDEGQVTHNWDEVDPDPNQLR 96
+ +S S F ++ N LY LP+ E S + G + VD D Q
Sbjct: 543 SSNVSLSLFVLDQNDNTPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNA 602
Query: 97 WKPFEIPKASQKKVDFVSGLHTLCGAGDIKSNNGL 131
W + + KAS+ + F GLHT G++++ L
Sbjct: 603 WLSYRLLKASEPGL-FAVGLHT----GEVRTARAL 632
>gi|11056024 protocadherin gamma subfamily A, 5 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 30.4 bits (67), Expect = 3.4
Identities = 26/95 (27%), Positives = 41/95 (43%), Gaps = 9/95 (9%)
Query: 41 AEQLSGSAFTCPRSTNKRSWLYRILPSVSHKPFE----SIDEGQVTHNWDEVDPDPNQLR 96
+ +S S F ++ N LY LP+ E S + G + VD D Q
Sbjct: 543 SSNVSLSLFVLDQNDNTPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDKDSGQNA 602
Query: 97 WKPFEIPKASQKKVDFVSGLHTLCGAGDIKSNNGL 131
W + + KAS+ + F GLHT G++++ L
Sbjct: 603 WLSYRLLKASEPGL-FAVGLHT----GEVRTARAL 632
>gi|190885497 Rho guanine nucleotide exchange factor 3 isoform 2
[Homo sapiens]
Length = 532
Score = 28.9 bits (63), Expect = 9.9
Identities = 10/30 (33%), Positives = 18/30 (60%)
Query: 108 KKVDFVSGLHTLCGAGDIKSNNGLAIHIFL 137
+K + LC G++K+N G+ +H+FL
Sbjct: 330 QKDSLIDSSRVLCCHGELKNNRGVKLHVFL 359
>gi|190885495 Rho guanine nucleotide exchange factor 3 isoform 1
[Homo sapiens]
Length = 558
Score = 28.9 bits (63), Expect = 9.9
Identities = 10/30 (33%), Positives = 18/30 (60%)
Query: 108 KKVDFVSGLHTLCGAGDIKSNNGLAIHIFL 137
+K + LC G++K+N G+ +H+FL
Sbjct: 356 QKDSLIDSSRVLCCHGELKNNRGVKLHVFL 385
>gi|9506401 Rho guanine nucleotide exchange factor 3 isoform 3 [Homo
sapiens]
Length = 526
Score = 28.9 bits (63), Expect = 9.9
Identities = 10/30 (33%), Positives = 18/30 (60%)
Query: 108 KKVDFVSGLHTLCGAGDIKSNNGLAIHIFL 137
+K + LC G++K+N G+ +H+FL
Sbjct: 324 QKDSLIDSSRVLCCHGELKNNRGVKLHVFL 353
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.138 0.444
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,599,307
Number of Sequences: 37866
Number of extensions: 928576
Number of successful extensions: 1615
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1610
Number of HSP's gapped (non-prelim): 15
length of query: 445
length of database: 18,247,518
effective HSP length: 105
effective length of query: 340
effective length of database: 14,271,588
effective search space: 4852339920
effective search space used: 4852339920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.