Guide to the Human Genome
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Search of human proteins with 115430099

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|115430099 thyroid stimulating hormone, beta precursor [Homo
sapiens]
         (138 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|115430099 thyroid stimulating hormone, beta precursor [Homo s...   300   3e-82
gi|66528995 follicle stimulating hormone, beta polypeptide precu...   107   2e-24
gi|4503791 follicle stimulating hormone, beta polypeptide precur...   107   2e-24
gi|4504989 luteinizing hormone beta subunit precursor [Homo sapi...   100   7e-22
gi|4502789 chorionic gonadotropin beta 3 subunit precursor [Homo...    96   9e-21
gi|15451748 chorionic gonadotropin, beta polypeptide 5 precursor...    96   9e-21
gi|132566538 chorionic gonadotropin, beta polypeptide 2 [Homo sa...    96   9e-21
gi|132566537 chorionic gonadotropin, beta polypeptide 1 [Homo sa...    96   9e-21
gi|15451750 chorionic gonadotropin, beta polypeptide 7 precursor...    96   9e-21
gi|15426252 chorionic gonadotropin, beta polypeptide 8 precursor...    96   9e-21
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    29   1.1  
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    29   1.1  
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    29   1.1  
gi|52317202 olfactory receptor, family 2, subfamily L, member 2 ...    29   1.1  
gi|14917117 keratin 33A [Homo sapiens]                                 27   7.0  
gi|15451921 platelet derived growth factor D isoform 2 precursor...    26   9.2  
gi|226442878 ADAMTS-like 5 [Homo sapiens]                              26   9.2  
gi|5031897 mab-21-like protein 1 [Homo sapiens]                        26   9.2  
gi|154937359 cysteine-rich PAK1 inhibitor [Homo sapiens]               26   9.2  

>gi|115430099 thyroid stimulating hormone, beta precursor [Homo
           sapiens]
          Length = 138

 Score =  300 bits (768), Expect = 3e-82
 Identities = 138/138 (100%), Positives = 138/138 (100%)

Query: 1   MTALFLMSMLFGLTCGQAMSFCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDINGKL 60
           MTALFLMSMLFGLTCGQAMSFCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDINGKL
Sbjct: 1   MTALFLMSMLFGLTCGQAMSFCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDINGKL 60

Query: 61  FLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAI 120
           FLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAI
Sbjct: 61  FLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAI 120

Query: 121 KTNYCTKPQKSYLVGFSV 138
           KTNYCTKPQKSYLVGFSV
Sbjct: 121 KTNYCTKPQKSYLVGFSV 138


>gi|66528995 follicle stimulating hormone, beta polypeptide
           precursor [Homo sapiens]
          Length = 129

 Score =  107 bits (268), Expect = 2e-24
 Identities = 49/122 (40%), Positives = 72/122 (59%), Gaps = 4/122 (3%)

Query: 7   MSMLFGLTCGQAM--SFCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDINGKLFLPK 64
           +   F   C +A+  + C  T  T+ IE+ EC +C++INTT CAGYC TRD+  K   P 
Sbjct: 4   LQFFFLFCCWKAICCNSCELTNITIAIEKEECRFCISINTTWCAGYCYTRDLVYKD--PA 61

Query: 65  YALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAIKTNY 124
               Q  CT+++ +Y TV +PGC  H    ++YPVA  C CGKC++D +DC    +  +Y
Sbjct: 62  RPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTVRGLGPSY 121

Query: 125 CT 126
           C+
Sbjct: 122 CS 123


>gi|4503791 follicle stimulating hormone, beta polypeptide precursor
           [Homo sapiens]
          Length = 129

 Score =  107 bits (268), Expect = 2e-24
 Identities = 49/122 (40%), Positives = 72/122 (59%), Gaps = 4/122 (3%)

Query: 7   MSMLFGLTCGQAM--SFCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDINGKLFLPK 64
           +   F   C +A+  + C  T  T+ IE+ EC +C++INTT CAGYC TRD+  K   P 
Sbjct: 4   LQFFFLFCCWKAICCNSCELTNITIAIEKEECRFCISINTTWCAGYCYTRDLVYKD--PA 61

Query: 65  YALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAIKTNY 124
               Q  CT+++ +Y TV +PGC  H    ++YPVA  C CGKC++D +DC    +  +Y
Sbjct: 62  RPKIQKTCTFKELVYETVRVPGCAHHADSLYTYPVATQCHCGKCDSDSTDCTVRGLGPSY 121

Query: 125 CT 126
           C+
Sbjct: 122 CS 123


>gi|4504989 luteinizing hormone beta subunit precursor [Homo
           sapiens]
          Length = 141

 Score = 99.8 bits (247), Expect = 7e-22
 Identities = 50/114 (43%), Positives = 64/114 (56%), Gaps = 2/114 (1%)

Query: 21  FCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDINGKLFLPKYALSQDVCTYRDFIYR 80
           +C P    + +E+  C  C+T+NTTICAGYC T     +  LP   L Q VCTYRD  + 
Sbjct: 28  WCHPINAILAVEKEGCPVCITVNTTICAGYCPTMMRVLQAVLPP--LPQVVCTYRDVRFE 85

Query: 81  TVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDCIHEAIKTNYCTKPQKSYLV 134
           ++ +PGCP  V P  S+PVALSC+CG C    SDC         C  PQ S L+
Sbjct: 86  SIRLPGCPRGVDPVVSFPVALSCRCGPCRRSTSDCGGPKDHPLTCDHPQLSGLL 139


>gi|4502789 chorionic gonadotropin beta 3 subunit precursor [Homo
           sapiens]
          Length = 165

 Score = 95.9 bits (237), Expect = 9e-21
 Identities = 46/96 (47%), Positives = 58/96 (60%), Gaps = 6/96 (6%)

Query: 22  CIPTEYTMHIERRECAYCLTINTTICAGYC--MTRDINGKLFLPKYALSQDVCTYRDFIY 79
           C P   T+ +E+  C  C+T+NTTICAGYC  MTR + G L     AL Q VC YRD  +
Sbjct: 29  CRPINATLAVEKEGCPVCITVNTTICAGYCPTMTRVLQGVL----PALPQVVCNYRDVRF 84

Query: 80  RTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDC 115
            ++ +PGCP  V P  SY VALSC+C  C    +DC
Sbjct: 85  ESIRLPGCPRGVNPVVSYAVALSCQCALCRRSTTDC 120


>gi|15451748 chorionic gonadotropin, beta polypeptide 5 precursor
           [Homo sapiens]
          Length = 165

 Score = 95.9 bits (237), Expect = 9e-21
 Identities = 46/96 (47%), Positives = 58/96 (60%), Gaps = 6/96 (6%)

Query: 22  CIPTEYTMHIERRECAYCLTINTTICAGYC--MTRDINGKLFLPKYALSQDVCTYRDFIY 79
           C P   T+ +E+  C  C+T+NTTICAGYC  MTR + G L     AL Q VC YRD  +
Sbjct: 29  CRPINATLAVEKEGCPVCITVNTTICAGYCPTMTRVLQGVL----PALPQVVCNYRDVRF 84

Query: 80  RTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDC 115
            ++ +PGCP  V P  SY VALSC+C  C    +DC
Sbjct: 85  ESIRLPGCPRGVNPVVSYAVALSCQCALCRRSTTDC 120


>gi|132566538 chorionic gonadotropin, beta polypeptide 2 [Homo
           sapiens]
          Length = 163

 Score = 95.9 bits (237), Expect = 9e-21
 Identities = 46/96 (47%), Positives = 58/96 (60%), Gaps = 6/96 (6%)

Query: 22  CIPTEYTMHIERRECAYCLTINTTICAGYC--MTRDINGKLFLPKYALSQDVCTYRDFIY 79
           C P   T+ +E+  C  C+T+NTTICAGYC  MTR + G L     AL Q VC YRD  +
Sbjct: 27  CRPINATLAVEKEGCPVCITVNTTICAGYCPTMTRVLQGVL----PALPQVVCNYRDVRF 82

Query: 80  RTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDC 115
            ++ +PGCP  V P  SY VALSC+C  C    +DC
Sbjct: 83  ESIRLPGCPRGVNPVVSYAVALSCQCALCRRSTTDC 118


>gi|132566537 chorionic gonadotropin, beta polypeptide 1 [Homo
           sapiens]
          Length = 155

 Score = 95.9 bits (237), Expect = 9e-21
 Identities = 46/96 (47%), Positives = 58/96 (60%), Gaps = 6/96 (6%)

Query: 22  CIPTEYTMHIERRECAYCLTINTTICAGYC--MTRDINGKLFLPKYALSQDVCTYRDFIY 79
           C P   T+ +E+  C  C+T+NTTICAGYC  MTR + G L     AL Q VC YRD  +
Sbjct: 27  CRPINATLAVEKEGCPVCITVNTTICAGYCPTMTRVLQGVL----PALPQVVCNYRDVRF 82

Query: 80  RTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDC 115
            ++ +PGCP  V P  SY VALSC+C  C    +DC
Sbjct: 83  ESIRLPGCPRGVNPVVSYAVALSCQCALCRRSTTDC 118


>gi|15451750 chorionic gonadotropin, beta polypeptide 7 precursor
           [Homo sapiens]
          Length = 165

 Score = 95.9 bits (237), Expect = 9e-21
 Identities = 46/96 (47%), Positives = 58/96 (60%), Gaps = 6/96 (6%)

Query: 22  CIPTEYTMHIERRECAYCLTINTTICAGYC--MTRDINGKLFLPKYALSQDVCTYRDFIY 79
           C P   T+ +E+  C  C+T+NTTICAGYC  MTR + G L     AL Q VC YRD  +
Sbjct: 29  CRPINATLAVEKEGCPVCITVNTTICAGYCPTMTRVLQGVL----PALPQVVCNYRDVRF 84

Query: 80  RTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDC 115
            ++ +PGCP  V P  SY VALSC+C  C    +DC
Sbjct: 85  ESIRLPGCPRGVNPVVSYAVALSCQCALCRRSTTDC 120


>gi|15426252 chorionic gonadotropin, beta polypeptide 8 precursor
           [Homo sapiens]
          Length = 165

 Score = 95.9 bits (237), Expect = 9e-21
 Identities = 46/96 (47%), Positives = 58/96 (60%), Gaps = 6/96 (6%)

Query: 22  CIPTEYTMHIERRECAYCLTINTTICAGYC--MTRDINGKLFLPKYALSQDVCTYRDFIY 79
           C P   T+ +E+  C  C+T+NTTICAGYC  MTR + G L     AL Q VC YRD  +
Sbjct: 29  CRPINATLAVEKEGCPVCITVNTTICAGYCPTMTRVLQGVL----PALPQVVCNYRDVRF 84

Query: 80  RTVEIPGCPLHVAPYFSYPVALSCKCGKCNTDYSDC 115
            ++ +PGCP  V P  SY VALSC+C  C    +DC
Sbjct: 85  ESIRLPGCPRGVNPVVSYAVALSCQCALCRRSTTDC 120


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
           [Homo sapiens]
          Length = 2004

 Score = 29.3 bits (64), Expect = 1.1
 Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 12/108 (11%)

Query: 31  IERRECAYCLTINTTICAGYCMTRDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLH 90
           I R+       ++  +   YC    +  KLFL    L  DV  +  ++    ++ GC  H
Sbjct: 570 IYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDVKGC--H 627

Query: 91  VAPYFSYPVALSCKCGKCNTDYS-DCIHEAIKTNYCTKPQKSYLVGFS 137
           +  YFS       K   C   Y+  CI   I   Y  K    +L+ FS
Sbjct: 628 LVGYFS-------KEKHCQQKYNVSCI--MILPQYQRKGYGRFLIDFS 666


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
           [Homo sapiens]
          Length = 2004

 Score = 29.3 bits (64), Expect = 1.1
 Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 12/108 (11%)

Query: 31  IERRECAYCLTINTTICAGYCMTRDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLH 90
           I R+       ++  +   YC    +  KLFL    L  DV  +  ++    ++ GC  H
Sbjct: 570 IYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDVKGC--H 627

Query: 91  VAPYFSYPVALSCKCGKCNTDYS-DCIHEAIKTNYCTKPQKSYLVGFS 137
           +  YFS       K   C   Y+  CI   I   Y  K    +L+ FS
Sbjct: 628 LVGYFS-------KEKHCQQKYNVSCI--MILPQYQRKGYGRFLIDFS 666


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
           [Homo sapiens]
          Length = 2004

 Score = 29.3 bits (64), Expect = 1.1
 Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 12/108 (11%)

Query: 31  IERRECAYCLTINTTICAGYCMTRDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLH 90
           I R+       ++  +   YC    +  KLFL    L  DV  +  ++    ++ GC  H
Sbjct: 570 IYRKNNISVFEVDGNVSTIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVLTQNDVKGC--H 627

Query: 91  VAPYFSYPVALSCKCGKCNTDYS-DCIHEAIKTNYCTKPQKSYLVGFS 137
           +  YFS       K   C   Y+  CI   I   Y  K    +L+ FS
Sbjct: 628 LVGYFS-------KEKHCQQKYNVSCI--MILPQYQRKGYGRFLIDFS 666


>gi|52317202 olfactory receptor, family 2, subfamily L, member 2
           [Homo sapiens]
          Length = 312

 Score = 29.3 bits (64), Expect = 1.1
 Identities = 26/112 (23%), Positives = 43/112 (38%), Gaps = 18/112 (16%)

Query: 9   MLFGLTCGQAMSFCIPTEYTMHIERRECAYCLT-------INT------TICAGYCMTRD 55
           +L  +   + ++ C P  Y + I +R C   +T       IN+       +C  YC +R 
Sbjct: 113 LLTSMAYDRYVAICFPLHYPIRISKRVCVMMITGSWMISSINSCAHTVYALCIPYCKSRA 172

Query: 56  INGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVALSCKCGK 107
           IN   F    A+    CT       TV +      V P+      ++C  G+
Sbjct: 173 IN-HFFCDVPAMLTLACTDTWVYESTVFLSSTIFLVLPF----TGIACSYGR 219


>gi|14917117 keratin 33A [Homo sapiens]
          Length = 404

 Score = 26.6 bits (57), Expect = 7.0
 Identities = 10/24 (41%), Positives = 11/24 (45%)

Query: 87  CPLHVAPYFSYPVALSCKCGKCNT 110
           C     P  S P  L  +CG CNT
Sbjct: 378 CDKSTGPCISNPCGLRARCGPCNT 401


>gi|15451921 platelet derived growth factor D isoform 2 precursor
          [Homo sapiens]
          Length = 364

 Score = 26.2 bits (56), Expect = 9.2
 Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 5/62 (8%)

Query: 42 INTTICAGYCMTRDINGKLFLPKYALSQDVCTYRDFIYR---TVEIPGCPLHVAPYF--S 96
          + T ICA +C  RD +           ++    RD +YR   T+++ G     +P F  S
Sbjct: 7  VYTLICANFCSCRDTSATPQSASIKALRNANLRRDDLYRRDETIQVKGNGYVQSPRFPNS 66

Query: 97 YP 98
          YP
Sbjct: 67 YP 68


>gi|226442878 ADAMTS-like 5 [Homo sapiens]
          Length = 471

 Score = 26.2 bits (56), Expect = 9.2
 Identities = 23/98 (23%), Positives = 38/98 (38%), Gaps = 15/98 (15%)

Query: 4   LFLMSMLFGLTCGQAMSFCIPTEYTMHIERRECAYCLTINTTICAGYCMTRDINGKLFLP 63
           LFL ++L    CG  +S   P E+T  +    C+       ++ +  C+         LP
Sbjct: 18  LFLWALL---NCGLGVSAQGPGEWTPWVSWTRCSSSCGRGVSVRSRRCLR--------LP 66

Query: 64  KYALSQDVCTYRDFIYRTVEIPGCPLHVAPYFSYPVAL 101
                ++ C      YR  ++P CP    P+     AL
Sbjct: 67  ----GEEPCWGDSHEYRLCQLPDCPPGAVPFRDLQCAL 100


>gi|5031897 mab-21-like protein 1 [Homo sapiens]
          Length = 359

 Score = 26.2 bits (56), Expect = 9.2
 Identities = 16/72 (22%), Positives = 29/72 (40%), Gaps = 1/72 (1%)

Query: 34  RECAYCLTINTTICAGYCMTRDINGKLFLPKYALSQDVCTYRDFIYRTVEIPGCPLHVAP 93
           R+ +  L +     +GY   R I  + F    A + D C+YRD +    +     L +  
Sbjct: 106 RKRSMSLWVEFITASGYLSARKIRSR-FQTLVAQAVDKCSYRDVVKMVADTSEVKLRIRD 164

Query: 94  YFSYPVALSCKC 105
            +   +  + KC
Sbjct: 165 RYVVQITPAFKC 176


>gi|154937359 cysteine-rich PAK1 inhibitor [Homo sapiens]
          Length = 446

 Score = 26.2 bits (56), Expect = 9.2
 Identities = 16/53 (30%), Positives = 21/53 (39%), Gaps = 8/53 (15%)

Query: 82  VEIPGCPLHVAPYFSYPVALSCKCG------KCNTDYSDCIHEAIKTNYCTKP 128
           VE P  P H   +   P A +C CG       C      C H+A+   +C  P
Sbjct: 359 VECP--PAHTRAHVECPPAHTCPCGVPACSHTCPCGVPACSHKALAWWFCRFP 409


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.140    0.471 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,518,079
Number of Sequences: 37866
Number of extensions: 229782
Number of successful extensions: 675
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 652
Number of HSP's gapped (non-prelim): 22
length of query: 138
length of database: 18,247,518
effective HSP length: 91
effective length of query: 47
effective length of database: 14,801,712
effective search space: 695680464
effective search space used: 695680464
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 56 (26.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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