Search of human proteins with 224451075

Search of human proteins with 224451075

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|224451075 endo/exonuclease (5'-3'), endonuclease G-like
isoform 2 precursor [Homo sapiens]
         (318 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|224451075 endo/exonuclease (5'-3'), endonuclease G-like isofo...   637   0.0  
gi|224451073 endo/exonuclease (5'-3'), endonuclease G-like isofo...   614   e-176
gi|53759134 endonuclease G precursor [Homo sapiens]                   163   2e-40
gi|111160296 ectonucleotide pyrophosphatase/phosphodiesterase 3 ...    39   0.008
gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1 ...    36   0.040
gi|148225659 endonuclease domain containing 1 [Homo sapiens]           34   0.20 
gi|46852174 kinesin family member 3A [Homo sapiens]                    32   0.97 
gi|4885349 G protein-coupled receptor kinase 5 [Homo sapiens]          30   2.8  
gi|88759339 aster-associated protein [Homo sapiens]                    30   3.7  
gi|8923271 coiled-coil domain containing 49 [Homo sapiens]             30   3.7  
gi|40354205 aldolase B, fructose-bisphosphate [Homo sapiens]           29   4.8  
gi|41152097 DNA segment on chromosome X and Y (unique) 155 expre...    29   4.8  
gi|28559039 mediator complex subunit 1 [Homo sapiens]                  29   6.3  
gi|227497884 brain-enriched guanylate kinase-associated protein ...    28   8.2  
gi|13124765 brain-enriched guanylate kinase-associated protein [...    28   8.2  
gi|122937396 coiled-coil domain containing 150 [Homo sapiens]          28   8.2  

>gi|224451075 endo/exonuclease (5'-3'), endonuclease G-like isoform
           2 precursor [Homo sapiens]
          Length = 318

 Score =  637 bits (1644), Expect = 0.0
 Identities = 318/318 (100%), Positives = 318/318 (100%)

Query: 1   MAIKSIASRLRGSRRFLSGFVAGAVVGAAGAGLAALQFFRSQGAEGALTGKQPDGDADRK 60
           MAIKSIASRLRGSRRFLSGFVAGAVVGAAGAGLAALQFFRSQGAEGALTGKQPDGDADRK
Sbjct: 1   MAIKSIASRLRGSRRFLSGFVAGAVVGAAGAGLAALQFFRSQGAEGALTGKQPDGDADRK 60

Query: 61  HCKFKPDPNIPPTFSAFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLSNIVPQDFDN 120
           HCKFKPDPNIPPTFSAFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLSNIVPQDFDN
Sbjct: 61  HCKFKPDPNIPPTFSAFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLSNIVPQDFDN 120

Query: 121 NSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYK 180
           NSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYK
Sbjct: 121 NSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYK 180

Query: 181 VILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDI 240
           VILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDI
Sbjct: 181 VILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDI 240

Query: 241 RNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKK 300
           RNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKK
Sbjct: 241 RNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKK 300

Query: 301 LEELKAKEQSGTQIRKPS 318
           LEELKAKEQSGTQIRKPS
Sbjct: 301 LEELKAKEQSGTQIRKPS 318


>gi|224451073 endo/exonuclease (5'-3'), endonuclease G-like isoform
           1 precursor [Homo sapiens]
          Length = 368

 Score =  614 bits (1583), Expect = e-176
 Identities = 318/368 (86%), Positives = 318/368 (86%), Gaps = 50/368 (13%)

Query: 1   MAIKSIASRLRGSRRFLSGFVAGAVVGAAGAGLAALQFFRSQGAEGALTGKQPDG----- 55
           MAIKSIASRLRGSRRFLSGFVAGAVVGAAGAGLAALQFFRSQGAEGALTGKQPDG     
Sbjct: 1   MAIKSIASRLRGSRRFLSGFVAGAVVGAAGAGLAALQFFRSQGAEGALTGKQPDGSAEKA 60

Query: 56  ---------------------------------------------DADRKHCKFKPDPNI 70
                                                        DADRKHCKFKPDPNI
Sbjct: 61  VLEQFGFPLTGTEARCYTNHALSYDQAKRVPRWVLEHISKSKIMGDADRKHCKFKPDPNI 120

Query: 71  PPTFSAFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEM 130
           PPTFSAFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEM
Sbjct: 121 PPTFSAFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEM 180

Query: 131 YCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVS 190
           YCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVS
Sbjct: 181 YCRELTERFEDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVS 240

Query: 191 TEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCK 250
           TEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCK
Sbjct: 241 TEPLALGAFVVPNEAIGFQPQLTEFQVSLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCK 300

Query: 251 LLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEELKAKEQS 310
           LLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEELKAKEQS
Sbjct: 301 LLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEELKAKEQS 360

Query: 311 GTQIRKPS 318
           GTQIRKPS
Sbjct: 361 GTQIRKPS 368


>gi|53759134 endonuclease G precursor [Homo sapiens]
          Length = 297

 Score =  163 bits (412), Expect = 2e-40
 Identities = 82/198 (41%), Positives = 123/198 (62%), Gaps = 6/198 (3%)

Query: 40  RSQGAEGALTGKQPD---GDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGHMAPAGN 96
           R++GA   +   +P+   GD DR+ C F+ D ++     A N DY GSG+ RGH+A A N
Sbjct: 88  RTRGALWVVEQLRPERLRGDGDRRECDFREDDSVHAYHRATNADYRGSGFDRGHLAAAAN 147

Query: 97  NKFSSKAMAETFYLSNIVPQDFDNNSGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRG 156
           +++S KAM +TFYLSN+ PQ    N   WN +E Y R LT  +++V+V +GPL LP+T  
Sbjct: 148 HRWSQKAMDDTFYLSNVAPQVPHLNQNAWNNLEKYSRSLTRSYQNVYVCTGPLFLPRTEA 207

Query: 157 DGKKIVSYQVIGEDNVAVPSHLYKVILARRSSVSTEPLALGAFVVPNEAIGFQPQLTEFQ 216
           DGK  V YQVIG+++VAVP+H +KV++   +    E   L  +V+PN  +     L  F 
Sbjct: 208 DGKSYVKYQVIGKNHVAVPTHFFKVLILEAAGGQIE---LRTYVMPNAPVDEAIPLERFL 264

Query: 217 VSLQDLEKLSGLVFFPHL 234
           V ++ +E+ SGL+F P++
Sbjct: 265 VPIESIERASGLLFVPNI 282


>gi|111160296 ectonucleotide pyrophosphatase/phosphodiesterase 3
           [Homo sapiens]
          Length = 875

 Score = 38.5 bits (88), Expect = 0.008
 Identities = 47/207 (22%), Positives = 91/207 (43%), Gaps = 29/207 (14%)

Query: 65  KPDPNIPPTFSAFNEDYVGS-GWSRGHMAPAGNNKFSSKAMAETFYLSNIVP--QDFDNN 121
           + D  +PP+ S     Y+     + G + P  +N+ +S +  +    SN+VP  ++F   
Sbjct: 666 RADVRVPPSESQKCSFYLADKNITHGFLYPPASNR-TSDSQYDALITSNLVPMYEEFRKM 724

Query: 122 SGYWNRIEMYCRELTERFEDVWVVSGPLTLPQTRG--DGKKIVSYQVIGEDNVAVPSHLY 179
             Y++ + +  +  TER   V VVSGP+      G  D    ++  +   D V +P+H +
Sbjct: 725 WDYFHSV-LLIKHATER-NGVNVVSGPIFDYNYDGHFDAPDEITKHLANTD-VPIPTHYF 781

Query: 180 KVILARRSSVSTEPLALG-----AFVVPN-------------EAIGFQPQLTEFQVSLQD 221
            V+ + ++   T     G      F++P+             EA+  + + T     ++D
Sbjct: 782 VVLTSCKNKSHTPENCPGWLDVLPFIIPHRPTNVESCPEGKPEALWVEERFTAHIARVRD 841

Query: 222 LEKLSGLVFFPHLDRTSDIRNICSVDT 248
           +E L+GL F+   D+   +  I  + T
Sbjct: 842 VELLTGLDFYQ--DKVQPVSEILQLKT 866


>gi|170650661 ectonucleotide pyrophosphatase/phosphodiesterase 1
           [Homo sapiens]
          Length = 925

 Score = 36.2 bits (82), Expect = 0.040
 Identities = 41/168 (24%), Positives = 73/168 (43%), Gaps = 25/168 (14%)

Query: 87  SRGHMAPAGNNKFSSKAMAETFYLSNIVP--QDFDNNSGYWNRIEMYCRELTERFEDVWV 144
           S G ++P   NK SS   +E    +NIVP  Q F     Y++  +   R+  E    V V
Sbjct: 736 SYGFLSPPQLNKNSSGIYSEALLTTNIVPMYQSFQVIWRYFH--DTLLRKYAEERNGVNV 793

Query: 145 VSGPLTLPQTRGDGKKIVSY----QVIGEDNVAVPSHLYKVILARRSSVST----EPLAL 196
           VSGP+      G    + +     +VI    + +P+H + V+ + + +  T    E L  
Sbjct: 794 VSGPVFDFDYDGRCDSLENLRQKRRVIRNQEILIPTHFFIVLTSCKDTSQTPLHCENLDT 853

Query: 197 GAFVVP-------------NEAIGFQPQLTEFQVSLQDLEKLSGLVFF 231
            AF++P             +++   +  L   +  + D+E ++GL F+
Sbjct: 854 LAFILPHRTDNSESCVHGKHDSSWVEELLMLHRARITDVEHITGLSFY 901


>gi|148225659 endonuclease domain containing 1 [Homo sapiens]
          Length = 500

 Score = 33.9 bits (76), Expect = 0.20
 Identities = 34/109 (31%), Positives = 50/109 (45%), Gaps = 22/109 (20%)

Query: 76  AFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLSNIVP--QDFDNNSGYWNRIEMYCR 133
           A N DY+ S + RG + P      SS     TF L+N  P  Q F     Y N   +  R
Sbjct: 129 ALNTDYLDSDYQRGQLYPF---SLSSDVQVATFTLTNSAPMTQSFQER-WYVNLHSLMDR 184

Query: 134 ELTERF---EDVWVVSGPLTLPQTRGDGKKIVSYQVIGEDNVAVPSHLY 179
            LT +    ED+++++G  T+P           Y+V  +D VAVP  ++
Sbjct: 185 ALTPQCGSGEDLYILTG--TVPS---------DYRV--KDKVAVPEFVW 220


>gi|46852174 kinesin family member 3A [Homo sapiens]
          Length = 699

 Score = 31.6 bits (70), Expect = 0.97
 Identities = 18/47 (38%), Positives = 29/47 (61%), Gaps = 3/47 (6%)

Query: 271 SVLRLEKIMENLKN-AEI--EPDDYFMSRYEKKLEELKAKEQSGTQI 314
           S LR     +N+KN A I  +P D  + +++K++EELK K + G +I
Sbjct: 334 STLRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEEGEEI 380


>gi|4885349 G protein-coupled receptor kinase 5 [Homo sapiens]
          Length = 590

 Score = 30.0 bits (66), Expect = 2.8
 Identities = 16/69 (23%), Positives = 31/69 (44%)

Query: 223 EKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENL 282
           +K   ++ FPH+ +  D+R     D C L D Q     L  +  E    +    + ++++
Sbjct: 28  KKWKEILKFPHISQCEDLRRTIDRDYCSLCDKQPIGRLLFRQFCETRPGLECYIQFLDSV 87

Query: 283 KNAEIEPDD 291
              E+ PD+
Sbjct: 88  AEYEVTPDE 96


>gi|88759339 aster-associated protein [Homo sapiens]
          Length = 647

 Score = 29.6 bits (65), Expect = 3.7
 Identities = 14/36 (38%), Positives = 19/36 (52%)

Query: 41  SQGAEGALTGKQPDGDADRKHCKFKPDPNIPPTFSA 76
           S G+EG  +GK P+ +    H   K D N   +FSA
Sbjct: 257 SPGSEGNASGKDPNEEITENHNSLKSDENKENSFSA 292


>gi|8923271 coiled-coil domain containing 49 [Homo sapiens]
          Length = 425

 Score = 29.6 bits (65), Expect = 3.7
 Identities = 14/43 (32%), Positives = 21/43 (48%)

Query: 30  GAGLAALQFFRSQGAEGALTGKQPDGDADRKHCKFKPDPNIPP 72
           G GL      R+QG +G LT +Q  G   + H + +   + PP
Sbjct: 226 GYGLQVRNSDRNQGLQGPLTAEQKRGHGMKNHSRSRSSSHSPP 268


>gi|40354205 aldolase B, fructose-bisphosphate [Homo sapiens]
          Length = 364

 Score = 29.3 bits (64), Expect = 4.8
 Identities = 10/30 (33%), Positives = 18/30 (60%)

Query: 53  PDGDADRKHCKFKPDPNIPPTFSAFNEDYV 82
           PDGD D +HC++  +  +   + A N+ +V
Sbjct: 193 PDGDHDLEHCQYVTEKVLAAVYKALNDHHV 222


>gi|41152097 DNA segment on chromosome X and Y (unique) 155
           expressed sequence isoform 1 [Homo sapiens]
          Length = 695

 Score = 29.3 bits (64), Expect = 4.8
 Identities = 18/50 (36%), Positives = 27/50 (54%)

Query: 264 RKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEELKAKEQSGTQ 313
           RK +    + R  K  E L+  E +  D  + R +KKLE+L+A+EQ   Q
Sbjct: 304 RKQKELEELERERKREEKLRKREQKQRDRELRRNQKKLEKLQAEEQKQLQ 353


>gi|28559039 mediator complex subunit 1 [Homo sapiens]
          Length = 1581

 Score = 28.9 bits (63), Expect = 6.3
 Identities = 18/64 (28%), Positives = 27/64 (42%)

Query: 52   QPDGDADRKHCKFKPDPNIPPTFSAFNEDYVGSGWSRGHMAPAGNNKFSSKAMAETFYLS 111
            +P G +D+     KP P  PP+  A +    GSG S      + +   SS  +  +  LS
Sbjct: 1197 RPPGGSDKLASPMKPVPGTPPSSKAKSPISSGSGGSHMSGTSSSSGMKSSSGLGSSGSLS 1256

Query: 112  NIVP 115
               P
Sbjct: 1257 QKTP 1260


>gi|227497884 brain-enriched guanylate kinase-associated protein
           [Homo sapiens]
          Length = 593

 Score = 28.5 bits (62), Expect = 8.2
 Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 14/86 (16%)

Query: 10  LRGSRRFLSGFVAGAV---VGAAGAGLAALQFFRSQGAEGALTGKQPDGDADRKHCKFKP 66
           +RG  R LS    GA    V AAG         R  G  G   GK+ DG A   +  +K 
Sbjct: 414 MRGQWRPLSVEDIGAYSYPVSAAGRASPCSFSERYYGGAGGSPGKKADGRASPLYASYKA 473

Query: 67  DPNIPPTFSAFNEDYVGSGWSRGHMA 92
           D        +F+E   G   S+GH+A
Sbjct: 474 D--------SFSE---GDDLSQGHLA 488


>gi|13124765 brain-enriched guanylate kinase-associated protein
           [Homo sapiens]
          Length = 593

 Score = 28.5 bits (62), Expect = 8.2
 Identities = 28/86 (32%), Positives = 36/86 (41%), Gaps = 14/86 (16%)

Query: 10  LRGSRRFLSGFVAGAV---VGAAGAGLAALQFFRSQGAEGALTGKQPDGDADRKHCKFKP 66
           +RG  R LS    GA    V AAG         R  G  G   GK+ DG A   +  +K 
Sbjct: 414 MRGQWRPLSVEDIGAYSYPVSAAGRASPCSFSERYYGGAGGSPGKKADGRASPLYASYKA 473

Query: 67  DPNIPPTFSAFNEDYVGSGWSRGHMA 92
           D        +F+E   G   S+GH+A
Sbjct: 474 D--------SFSE---GDDLSQGHLA 488


>gi|122937396 coiled-coil domain containing 150 [Homo sapiens]
          Length = 1101

 Score = 28.5 bits (62), Expect = 8.2
 Identities = 15/46 (32%), Positives = 26/46 (56%), Gaps = 1/46 (2%)

Query: 256 EFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKL 301
           +  L+LS  K   A+++ R+++I + LK  E+  D Y    YE+ L
Sbjct: 898 QIKLHLSA-KANNAQNIERMKQIEKELKQMELIKDQYQKKNYEQSL 942


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,978,152
Number of Sequences: 37866
Number of extensions: 562888
Number of successful extensions: 1403
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 1389
Number of HSP's gapped (non-prelim): 20
length of query: 318
length of database: 18,247,518
effective HSP length: 102
effective length of query: 216
effective length of database: 14,385,186
effective search space: 3107200176
effective search space used: 3107200176
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.