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Search of human proteins with 224451025
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|224451025 HOP homeobox isoform c [Homo sapiens]
(112 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|224451025 HOP homeobox isoform c [Homo sapiens] 233 2e-62
gi|224282187 HOP homeobox isoform a [Homo sapiens] 134 1e-32
gi|224451023 HOP homeobox isoform b [Homo sapiens] 99 9e-22
gi|21264589 HOP homeobox isoform b [Homo sapiens] 99 9e-22
gi|21264587 HOP homeobox isoform b [Homo sapiens] 99 9e-22
gi|189083832 inhibitor of growth family, member 4 isoform 6 [Hom... 29 0.71
gi|189083830 inhibitor of growth family, member 4 isoform 5 [Hom... 29 0.71
gi|189083821 inhibitor of growth family, member 4 isoform 9 [Hom... 29 0.71
gi|50083287 LIM homeobox 8 [Homo sapiens] 29 0.71
gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens] 28 1.6
gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens] 28 1.6
gi|189083828 inhibitor of growth family, member 4 isoform 4 [Hom... 28 2.1
gi|189083826 inhibitor of growth family, member 4 isoform 3 [Hom... 28 2.1
gi|38201670 inhibitor of growth family, member 4 isoform 1 [Homo... 28 2.1
gi|24308241 zinc finger and BTB domain containing 2 [Homo sapiens] 28 2.1
gi|224493895 t-complex 11 (mouse) like 1 [Homo sapiens] 27 2.7
gi|224493847 t-complex 11 (mouse) like 1 [Homo sapiens] 27 2.7
gi|33469974 activating transcription factor 4 [Homo sapiens] 27 2.7
gi|33469976 activating transcription factor 4 [Homo sapiens] 27 2.7
gi|170932518 paxillin isoform 3 [Homo sapiens] 27 3.5
gi|170932516 paxillin isoform 2 [Homo sapiens] 27 3.5
gi|170932514 paxillin isoform 1 [Homo sapiens] 27 3.5
gi|50593010 bisphosphoglycerate mutase 2 [Homo sapiens] 27 3.5
gi|27734799 REST corepressor 2 [Homo sapiens] 27 3.5
gi|33356170 myosin IXB isoform 1 [Homo sapiens] 26 6.0
gi|13376824 UL16 binding protein 2 [Homo sapiens] 26 7.8
gi|87578396 microtubule-associated protein 2 isoform 1 [Homo sap... 26 7.8
gi|83816964 Holliday junction recognition protein [Homo sapiens] 26 7.8
gi|188536004 zinc finger protein 469 [Homo sapiens] 26 7.8
gi|32880199 makorin ring finger protein 2 [Homo sapiens] 26 7.8
>gi|224451025 HOP homeobox isoform c [Homo sapiens]
Length = 112
Score = 233 bits (595), Expect = 2e-62
Identities = 112/112 (100%), Positives = 112/112 (100%)
Query: 1 MLIFLGCYRRRLEERAGTMSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGL 60
MLIFLGCYRRRLEERAGTMSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGL
Sbjct: 1 MLIFLGCYRRRLEERAGTMSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGL 60
Query: 61 SEEETQGSDLISRSKIWHPESSPQREGYPHDSLPCLAFDYFSLLPPQCKEMV 112
SEEETQGSDLISRSKIWHPESSPQREGYPHDSLPCLAFDYFSLLPPQCKEMV
Sbjct: 61 SEEETQGSDLISRSKIWHPESSPQREGYPHDSLPCLAFDYFSLLPPQCKEMV 112
>gi|224282187 HOP homeobox isoform a [Homo sapiens]
Length = 91
Score = 134 bits (338), Expect = 1e-32
Identities = 66/66 (100%), Positives = 66/66 (100%)
Query: 1 MLIFLGCYRRRLEERAGTMSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGL 60
MLIFLGCYRRRLEERAGTMSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGL
Sbjct: 1 MLIFLGCYRRRLEERAGTMSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGL 60
Query: 61 SEEETQ 66
SEEETQ
Sbjct: 61 SEEETQ 66
>gi|224451023 HOP homeobox isoform b [Homo sapiens]
Length = 73
Score = 98.6 bits (244), Expect = 9e-22
Identities = 48/48 (100%), Positives = 48/48 (100%)
Query: 19 MSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQ 66
MSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQ
Sbjct: 1 MSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQ 48
>gi|21264589 HOP homeobox isoform b [Homo sapiens]
Length = 73
Score = 98.6 bits (244), Expect = 9e-22
Identities = 48/48 (100%), Positives = 48/48 (100%)
Query: 19 MSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQ 66
MSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQ
Sbjct: 1 MSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQ 48
>gi|21264587 HOP homeobox isoform b [Homo sapiens]
Length = 73
Score = 98.6 bits (244), Expect = 9e-22
Identities = 48/48 (100%), Positives = 48/48 (100%)
Query: 19 MSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQ 66
MSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQ
Sbjct: 1 MSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQ 48
>gi|189083832 inhibitor of growth family, member 4 isoform 6 [Homo
sapiens]
Length = 179
Score = 29.3 bits (64), Expect = 0.71
Identities = 17/58 (29%), Positives = 27/58 (46%)
Query: 29 EDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQGSDLISRSKIWHPESSPQRE 86
+D+V++ + VDKH L EA L E++ + SD S S + Q+E
Sbjct: 80 DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKE 137
>gi|189083830 inhibitor of growth family, member 4 isoform 5 [Homo
sapiens]
Length = 225
Score = 29.3 bits (64), Expect = 0.71
Identities = 17/58 (29%), Positives = 27/58 (46%)
Query: 29 EDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQGSDLISRSKIWHPESSPQRE 86
+D+V++ + VDKH L EA L E++ + SD S S + Q+E
Sbjct: 56 DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKE 113
>gi|189083821 inhibitor of growth family, member 4 isoform 9 [Homo
sapiens]
Length = 249
Score = 29.3 bits (64), Expect = 0.71
Identities = 17/58 (29%), Positives = 27/58 (46%)
Query: 29 EDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQGSDLISRSKIWHPESSPQRE 86
+D+V++ + VDKH L EA L E++ + SD S S + Q+E
Sbjct: 80 DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKE 137
>gi|50083287 LIM homeobox 8 [Homo sapiens]
Length = 356
Score = 29.3 bits (64), Expect = 0.71
Identities = 23/88 (26%), Positives = 37/88 (42%), Gaps = 14/88 (15%)
Query: 28 TEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQGSDLISRSKIWHPESSPQREG 87
T DQ+++++ F + D +PD+ TL +A GLS Q +W + +
Sbjct: 233 TADQLQVMQAQFAQ-DNNPDAQTLQKLAERTGLSRRVIQ---------VWFQNCRARHKK 282
Query: 88 Y----PHDSLPCLAFDYFSLLPPQCKEM 111
+ S P A L PP +EM
Sbjct: 283 HVSPNHSSSTPVTAVPPSRLSPPMLEEM 310
>gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens]
Length = 377
Score = 28.1 bits (61), Expect = 1.6
Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 3/80 (3%)
Query: 28 TEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQ--GSDLISRSKIWHPESSPQR 85
T +Q+++++ F + D +PD+ TL +A GLS Q + +R K P+
Sbjct: 256 TAEQLQVMQAQFAQ-DNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTPQHPVPP 314
Query: 86 EGYPHDSLPCLAFDYFSLLP 105
G P LP D P
Sbjct: 315 SGAPPSRLPSALSDDIHYTP 334
>gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens]
Length = 392
Score = 28.1 bits (61), Expect = 1.6
Identities = 22/80 (27%), Positives = 35/80 (43%), Gaps = 3/80 (3%)
Query: 28 TEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQ--GSDLISRSKIWHPESSPQR 85
T +Q+++++ F + D +PD+ TL +A GLS Q + +R K P+
Sbjct: 256 TAEQLQVMQAQFAQ-DNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKKHTPQHPVPP 314
Query: 86 EGYPHDSLPCLAFDYFSLLP 105
G P LP D P
Sbjct: 315 SGAPPSRLPSALSDDIHYTP 334
>gi|189083828 inhibitor of growth family, member 4 isoform 4 [Homo
sapiens]
Length = 245
Score = 27.7 bits (60), Expect = 2.1
Identities = 15/46 (32%), Positives = 23/46 (50%)
Query: 29 EDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQGSDLISRS 74
+D+V++ + VDKH L EA L E++ + SD S S
Sbjct: 80 DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSS 125
>gi|189083826 inhibitor of growth family, member 4 isoform 3 [Homo
sapiens]
Length = 246
Score = 27.7 bits (60), Expect = 2.1
Identities = 15/46 (32%), Positives = 23/46 (50%)
Query: 29 EDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQGSDLISRS 74
+D+V++ + VDKH L EA L E++ + SD S S
Sbjct: 80 DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSS 125
>gi|38201670 inhibitor of growth family, member 4 isoform 1 [Homo
sapiens]
Length = 248
Score = 27.7 bits (60), Expect = 2.1
Identities = 15/46 (32%), Positives = 23/46 (50%)
Query: 29 EDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQGSDLISRS 74
+D+V++ + VDKH L EA L E++ + SD S S
Sbjct: 80 DDKVQLAMQTYEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSS 125
>gi|24308241 zinc finger and BTB domain containing 2 [Homo sapiens]
Length = 514
Score = 27.7 bits (60), Expect = 2.1
Identities = 15/45 (33%), Positives = 21/45 (46%)
Query: 50 TLCLIAAEAGLSEEETQGSDLISRSKIWHPESSPQREGYPHDSLP 94
TLC AA+ G E + +IS S++ H SP +G P
Sbjct: 294 TLCSNAADLGKDAMEVPEAGMISDSELQHISDSPIIDGQQQSETP 338
>gi|224493895 t-complex 11 (mouse) like 1 [Homo sapiens]
Length = 509
Score = 27.3 bits (59), Expect = 2.7
Identities = 16/39 (41%), Positives = 21/39 (53%), Gaps = 1/39 (2%)
Query: 56 AEAGLSEEETQGSDLISRSKIWHPESSPQREGYPHDSLP 94
+E GL E+ +G+D + I SSPQR PH S P
Sbjct: 21 SEEGL-EDAVEGADEALQKAIKSDSSSPQRVQRPHSSPP 58
>gi|224493847 t-complex 11 (mouse) like 1 [Homo sapiens]
Length = 509
Score = 27.3 bits (59), Expect = 2.7
Identities = 16/39 (41%), Positives = 21/39 (53%), Gaps = 1/39 (2%)
Query: 56 AEAGLSEEETQGSDLISRSKIWHPESSPQREGYPHDSLP 94
+E GL E+ +G+D + I SSPQR PH S P
Sbjct: 21 SEEGL-EDAVEGADEALQKAIKSDSSSPQRVQRPHSSPP 58
>gi|33469974 activating transcription factor 4 [Homo sapiens]
Length = 351
Score = 27.3 bits (59), Expect = 2.7
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 6/64 (9%)
Query: 36 EYNFNKVDKHPDSTTLCLIAAEAGLSEEET-----QGSDLISRSKIWHPESSPQREGYPH 90
E + + D+ PD T + + + EE+T G + S + P+ SP G P+
Sbjct: 185 EVDITEGDRKPDYTAYVAMIPQC-IKEEDTPSDNDSGICMSPESYLGSPQHSPSTRGSPN 243
Query: 91 DSLP 94
SLP
Sbjct: 244 RSLP 247
>gi|33469976 activating transcription factor 4 [Homo sapiens]
Length = 351
Score = 27.3 bits (59), Expect = 2.7
Identities = 18/64 (28%), Positives = 29/64 (45%), Gaps = 6/64 (9%)
Query: 36 EYNFNKVDKHPDSTTLCLIAAEAGLSEEET-----QGSDLISRSKIWHPESSPQREGYPH 90
E + + D+ PD T + + + EE+T G + S + P+ SP G P+
Sbjct: 185 EVDITEGDRKPDYTAYVAMIPQC-IKEEDTPSDNDSGICMSPESYLGSPQHSPSTRGSPN 243
Query: 91 DSLP 94
SLP
Sbjct: 244 RSLP 247
>gi|170932518 paxillin isoform 3 [Homo sapiens]
Length = 424
Score = 26.9 bits (58), Expect = 3.5
Identities = 15/59 (25%), Positives = 22/59 (37%), Gaps = 9/59 (15%)
Query: 59 GLSEEETQGSDLISRSKIWHPE---------SSPQREGYPHDSLPCLAFDYFSLLPPQC 108
G ++ G + + K WHPE R + D P DY +L P+C
Sbjct: 192 GACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRC 250
>gi|170932516 paxillin isoform 2 [Homo sapiens]
Length = 557
Score = 26.9 bits (58), Expect = 3.5
Identities = 15/59 (25%), Positives = 22/59 (37%), Gaps = 9/59 (15%)
Query: 59 GLSEEETQGSDLISRSKIWHPE---------SSPQREGYPHDSLPCLAFDYFSLLPPQC 108
G ++ G + + K WHPE R + D P DY +L P+C
Sbjct: 325 GACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRC 383
>gi|170932514 paxillin isoform 1 [Homo sapiens]
Length = 591
Score = 26.9 bits (58), Expect = 3.5
Identities = 15/59 (25%), Positives = 22/59 (37%), Gaps = 9/59 (15%)
Query: 59 GLSEEETQGSDLISRSKIWHPE---------SSPQREGYPHDSLPCLAFDYFSLLPPQC 108
G ++ G + + K WHPE R + D P DY +L P+C
Sbjct: 359 GACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRC 417
>gi|50593010 bisphosphoglycerate mutase 2 [Homo sapiens]
Length = 253
Score = 26.9 bits (58), Expect = 3.5
Identities = 28/89 (31%), Positives = 39/89 (43%), Gaps = 15/89 (16%)
Query: 11 RLEER-----AGTMSAETASGPTEDQVEILEYNFN-----KVDKHPDSTTLCLIAAEAGL 60
RL ER G AETA+ E+QV+I +F+ +KHP ++ AGL
Sbjct: 86 RLNERHYGGLTGLNKAETAAKHGEEQVKIWRRSFDIPPPPMDEKHPYYNSISKERRYAGL 145
Query: 61 SEEETQG----SDLISRS-KIWHPESSPQ 84
E D I+R+ W+ E PQ
Sbjct: 146 KPGELPTCESLKDTIARALPFWNEEIVPQ 174
>gi|27734799 REST corepressor 2 [Homo sapiens]
Length = 523
Score = 26.9 bits (58), Expect = 3.5
Identities = 16/56 (28%), Positives = 29/56 (51%), Gaps = 9/56 (16%)
Query: 62 EEETQGSDLISRSKIW--------HPESSPQREGYPHDSLPCLAFDYFSLLPPQCK 109
E+ + GS ++SRS+ H E E + HDS+ + +Y +++ P+CK
Sbjct: 6 EKPSAGSGILSRSRAKTVPNGGQPHSEDDSSEEEHSHDSMIRVGTNYQAVI-PECK 60
>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
Length = 2157
Score = 26.2 bits (56), Expect = 6.0
Identities = 21/85 (24%), Positives = 36/85 (42%), Gaps = 2/85 (2%)
Query: 13 EERAGTMSAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQGSDLIS 72
EE + E A G + + EIL + + + T L + S+EE S+ +
Sbjct: 1944 EELEVLLEEEAAGGDEDREKEILIERIQSIKEEKEDITYRLPELDPRGSDEENLDSETSA 2003
Query: 73 RSKIWHPESSPQ--REGYPHDSLPC 95
++ E + + EG P +LPC
Sbjct: 2004 STESLLEERAGRGASEGPPAPALPC 2028
>gi|13376824 UL16 binding protein 2 [Homo sapiens]
Length = 246
Score = 25.8 bits (55), Expect = 7.8
Identities = 10/35 (28%), Positives = 20/35 (57%), Gaps = 3/35 (8%)
Query: 72 SRSKIW---HPESSPQREGYPHDSLPCLAFDYFSL 103
S ++W HP + +E + +D + ++F YFS+
Sbjct: 153 SEKRMWTTVHPGARKMKEKWENDKVVAMSFHYFSM 187
>gi|87578396 microtubule-associated protein 2 isoform 1 [Homo sapiens]
Length = 1827
Score = 25.8 bits (55), Expect = 7.8
Identities = 14/50 (28%), Positives = 22/50 (44%)
Query: 20 SAETASGPTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQGSD 69
S E + P ++V + EY D + D TT+ +A +TQ D
Sbjct: 1347 SPEAPASPEREEVALSEYKTETYDDYKDETTIDDSIMDADSLWVDTQDDD 1396
>gi|83816964 Holliday junction recognition protein [Homo sapiens]
Length = 748
Score = 25.8 bits (55), Expect = 7.8
Identities = 11/28 (39%), Positives = 15/28 (53%)
Query: 45 HPDSTTLCLIAAEAGLSEEETQGSDLIS 72
HP ST + L+ LS +ET S +S
Sbjct: 219 HPSSTDMALVPRNDSLSLQETSSSSFLS 246
>gi|188536004 zinc finger protein 469 [Homo sapiens]
Length = 3925
Score = 25.8 bits (55), Expect = 7.8
Identities = 13/38 (34%), Positives = 19/38 (50%)
Query: 55 AAEAGLSEEETQGSDLISRSKIWHPESSPQREGYPHDS 92
++ A S EE+Q + S +HP + PQ G P S
Sbjct: 613 SSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPS 650
>gi|32880199 makorin ring finger protein 2 [Homo sapiens]
Length = 416
Score = 25.8 bits (55), Expect = 7.8
Identities = 17/70 (24%), Positives = 33/70 (47%), Gaps = 2/70 (2%)
Query: 27 PTEDQVEILEYNFNKVDKHPDSTTLCLIAAEAGLSEEETQGSDLISRSKIWHPESSPQRE 86
P+E I++ N ++ K T + +G++E +TQ S + + P+ SP+ +
Sbjct: 84 PSEVTASIVKTNSHEPGKREKRTLVLRDRNLSGMAERKTQPSMVSNPGSCSDPQPSPEMK 143
Query: 87 GYPHDSLPCL 96
PH L +
Sbjct: 144 --PHSYLDAI 151
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,806,147
Number of Sequences: 37866
Number of extensions: 190924
Number of successful extensions: 576
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 554
Number of HSP's gapped (non-prelim): 32
length of query: 112
length of database: 18,247,518
effective HSP length: 82
effective length of query: 30
effective length of database: 15,142,506
effective search space: 454275180
effective search space used: 454275180
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.