Guide to the Human Genome
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Search of human proteins with 222418615

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]
         (1044 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]               2117   0.0  
gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]     2031   0.0  
gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]     1941   0.0  
gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [...   920   0.0  
gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [...   902   0.0  
gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]        531   e-150
gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]        522   e-148
gi|49170034 integrin, alpha 8 [Homo sapiens]                          304   3e-82
gi|52485941 integrin, alpha 9 precursor [Homo sapiens]                277   3e-74
gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]                276   6e-74
gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]        276   6e-74
gi|56237029 integrin alpha 5 precursor [Homo sapiens]                 256   6e-68
gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]      256   8e-68
gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]            246   8e-65
gi|31657142 integrin, alpha 1 precursor [Homo sapiens]                227   5e-59
gi|67191027 integrin alpha 4 precursor [Homo sapiens]                 199   1e-50
gi|38569398 integrin, alpha 10 precursor [Homo sapiens]               184   4e-46
gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]      159   1e-38
gi|52485853 integrin, alpha 11 precursor [Homo sapiens]               158   3e-38
gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]      157   5e-38
gi|34452173 integrin alpha X precursor [Homo sapiens]                 146   1e-34
gi|116295258 integrin alpha 2 precursor [Homo sapiens]                145   1e-34
gi|148728188 integrin, alpha E precursor [Homo sapiens]               145   3e-34
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]      132   2e-30
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]       131   4e-30
gi|62548866 integrin, alpha D precursor [Homo sapiens]                124   6e-28
gi|29171717 glycosylphosphatidylinositol specific phospholipase ...    71   5e-12
gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo ...    47   1e-04
gi|169214874 PREDICTED: hypothetical protein [Homo sapiens]            33   1.1  
gi|169215109 PREDICTED: hypothetical protein [Homo sapiens]            33   1.1  

>gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]
          Length = 1044

 Score = 2117 bits (5486), Expect = 0.0
 Identities = 1044/1044 (100%), Positives = 1044/1044 (100%)

Query: 1    MAPFATPMVQALTTTRIQRQAEGFQCWRECGTRRSPFEGKETCAHRYEARQRVDQILETR 60
            MAPFATPMVQALTTTRIQRQAEGFQCWRECGTRRSPFEGKETCAHRYEARQRVDQILETR
Sbjct: 1    MAPFATPMVQALTTTRIQRQAEGFQCWRECGTRRSPFEGKETCAHRYEARQRVDQILETR 60

Query: 61   DMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAP 120
            DMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAP
Sbjct: 61   DMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAP 120

Query: 121  GTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGFSIDSGKGL 180
            GTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGFSIDSGKGL
Sbjct: 121  GTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGFSIDSGKGL 180

Query: 181  VRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDG 240
            VRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDG
Sbjct: 181  VRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDG 240

Query: 241  WPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQ 300
            WPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQ
Sbjct: 241  WPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQ 300

Query: 301  DGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQ 360
            DGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQ
Sbjct: 301  DGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQ 360

Query: 361  YPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIA 420
            YPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIA
Sbjct: 361  YPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIA 420

Query: 421  VPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGD 480
            VPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGD
Sbjct: 421  VPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGD 480

Query: 481  AMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFL 540
            AMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFL
Sbjct: 481  AMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFL 540

Query: 541  KQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTN 600
            KQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTN
Sbjct: 541  KQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTN 600

Query: 601  LPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNP 660
            LPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNP
Sbjct: 601  LPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNP 660

Query: 661  MKRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMA 720
            MKRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMA
Sbjct: 661  MKRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMA 720

Query: 721  IPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGK 780
            IPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGK
Sbjct: 721  IPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGK 780

Query: 781  WLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMS 840
            WLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMS
Sbjct: 781  WLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMS 840

Query: 841  WWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKS 900
            WWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKS
Sbjct: 841  WWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKS 900

Query: 901  LEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLA 960
            LEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLA
Sbjct: 901  LEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLA 960

Query: 961  LLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPD 1020
            LLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPD
Sbjct: 961  LLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPD 1020

Query: 1021 AHPILAADGHPELGPDGHPGPGTA 1044
            AHPILAADGHPELGPDGHPGPGTA
Sbjct: 1021 AHPILAADGHPELGPDGHPGPGTA 1044


>gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]
          Length = 1141

 Score = 2031 bits (5263), Expect = 0.0
 Identities = 1003/1003 (100%), Positives = 1003/1003 (100%)

Query: 42   TCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQ 101
            TCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQ
Sbjct: 139  TCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQ 198

Query: 102  QGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRL 161
            QGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRL
Sbjct: 199  QGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRL 258

Query: 162  IPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGE 221
            IPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGE
Sbjct: 259  IPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGE 318

Query: 222  RLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLC 281
            RLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLC
Sbjct: 319  RLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLC 378

Query: 282  GSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV 341
            GSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV
Sbjct: 379  GSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV 438

Query: 342  GIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPN 401
            GIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPN
Sbjct: 439  GIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPN 498

Query: 402  CAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPK 461
            CAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPK
Sbjct: 499  CAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPK 558

Query: 462  HQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPV 521
            HQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPV
Sbjct: 559  HQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPV 618

Query: 522  APILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTT 581
            APILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTT
Sbjct: 619  APILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTT 678

Query: 582  ALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEK 641
            ALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEK
Sbjct: 679  ALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEK 738

Query: 642  PLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHP 701
            PLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHP
Sbjct: 739  PLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHP 798

Query: 702  VSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLR 761
            VSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLR
Sbjct: 799  VSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLR 858

Query: 762  TLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRR 821
            TLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRR
Sbjct: 859  TLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRR 918

Query: 822  ELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLH 881
            ELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLH
Sbjct: 919  ELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLH 978

Query: 882  VWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAE 941
            VWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAE
Sbjct: 979  VWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAE 1038

Query: 942  GVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDRQQFKEE 1001
            GVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDRQQFKEE
Sbjct: 1039 GVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDRQQFKEE 1098

Query: 1002 KTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA 1044
            KTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA
Sbjct: 1099 KTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA 1141


>gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]
          Length = 1137

 Score = 1941 bits (5027), Expect = 0.0
 Identities = 971/1009 (96%), Positives = 975/1009 (96%), Gaps = 16/1009 (1%)

Query: 42   TCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQ 101
            TCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQ
Sbjct: 139  TCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQ 198

Query: 102  QGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPR- 160
            QGTAAAFSPDSHYLLFGAPGTYNWKG   V           ++D    +    K  DP  
Sbjct: 199  QGTAAAFSPDSHYLLFGAPGTYNWKGLLFV----------TNIDSSDPDQLVYKTLDPAD 248

Query: 161  LIPVPA-----NSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPE 215
             +P PA     NSY GFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPE
Sbjct: 249  RLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPE 308

Query: 216  VMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGI 275
            VMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGI
Sbjct: 309  VMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGI 368

Query: 276  SPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQV 335
            SPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQV
Sbjct: 369  SPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQV 428

Query: 336  LEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSI 395
            LEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSI
Sbjct: 429  LEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSI 488

Query: 396  DLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSR 455
            DLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSR
Sbjct: 489  DLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSR 548

Query: 456  NLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPG 515
            NLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPG
Sbjct: 549  NLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPG 608

Query: 516  QGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPM 575
            QGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPM
Sbjct: 609  QGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPM 668

Query: 576  DVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRA 635
            DVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRA
Sbjct: 669  DVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRA 728

Query: 636  LDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATIS 695
            LDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATIS
Sbjct: 729  LDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATIS 788

Query: 696  EQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSN 755
            EQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSN
Sbjct: 789  EQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSN 848

Query: 756  QGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDS 815
            QGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDS
Sbjct: 849  QGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDS 908

Query: 816  RDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFD 875
            RDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFD
Sbjct: 909  RDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFD 968

Query: 876  RAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDP 935
            RAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDP
Sbjct: 969  RAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDP 1028

Query: 936  MAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDR 995
            MAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDR
Sbjct: 1029 MAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDR 1088

Query: 996  QQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA 1044
            QQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA
Sbjct: 1089 QQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA 1137


>gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [Homo
            sapiens]
          Length = 1091

 Score =  920 bits (2377), Expect = 0.0
 Identities = 469/976 (48%), Positives = 659/976 (67%), Gaps = 31/976 (3%)

Query: 42   TCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQ 101
            TCAHRYE RQ V+   E+RD+ GRC+VLSQ+L I D++DGG+W FC+GR +GHE+FG CQ
Sbjct: 130  TCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLRGHEKFGSCQ 189

Query: 102  QGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRL 161
            QG AA F+ D HY++FGAPGTYNWKG  RVE       D+   +DGPYE GGE E D  L
Sbjct: 190  QGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESL 249

Query: 162  IPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKD-SASRLVPEVMLSG 220
            +PVPANSY GFS+DSGKG+V  +E++FV+GAPRANH GAVV+L++D  ++ L+PE +  G
Sbjct: 250  VPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDG 309

Query: 221  ERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRL 280
            E L S FGY +AV DLN DGW D+++GAP +F+R  E+GGAVYVY+NQ G W  + P+RL
Sbjct: 310  EGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGRWNNVKPIRL 369

Query: 281  CGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEA 340
             G+ DSMFGI++  +GD+NQDG+PDIAVGAP+D  GKVFIYHGS+ G+  KP+QVL+G +
Sbjct: 370  NGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPTQVLKGIS 429

Query: 341  VGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQP 400
                 FGYS++G++D+D N YPD+ VGSL+D+  +FR+RP++++   +++ P  IDL Q 
Sbjct: 430  ---PYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQK 486

Query: 401  NCAGGHS-VCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEE 459
               G  S +C+ ++ CF Y A P+ Y+P++++   L+A+ +RR  G   RV F ++   E
Sbjct: 487  TACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQG-SE 545

Query: 460  PKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLP 519
            PK+    T  LK Q  +VC +    LQ+N++DKLR I +T S  +Q P  RR+     LP
Sbjct: 546  PKYTQELT--LKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRV--NSLP 601

Query: 520  PVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTE-FQPLPMDVD 578
             V PILN+ +P T   ++HFLK+GCG+D +C SNL+L   +FCTR  + + F  LP+   
Sbjct: 602  EVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKL-EYKFCTREGNQDKFSYLPIQ-K 659

Query: 579  GTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALD- 637
            G   L  L  Q  I LE+ VTN PS+P  P  DGDDAHEA+L+   PD+L YS  R L  
Sbjct: 660  GVPEL-VLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRA 718

Query: 638  -PAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISE 696
             P ++  C++N+N S  +CELGNP KR + VTFYL+LST+ ++ +T +L++ L L T S 
Sbjct: 719  FPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSN 778

Query: 697  QE-LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSN 755
            Q+ L P++A+A+V IEL LS++G+A P Q++F G V GE+AM+SE +VGS ++YE  V N
Sbjct: 779  QDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVIN 838

Query: 756  QGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDS 815
             G+ L  LG+A LNI WP EI+NGKWLLY ++VE +G     +K  C P+  I  L++  
Sbjct: 839  LGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKG----LEKVTCEPQKEINSLNLTE 894

Query: 816  RDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFD 875
                R++ E  E+Q    R+         S   ++K  TL+C+    NCV   CPL   D
Sbjct: 895  SHNSRKKREITEKQIDDNRK--------FSLFAERKYQTLNCS-VNVNCVNIRCPLRGLD 945

Query: 876  RAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDP 935
              A L +  RLWNSTFLEEYS +  L++++RA I V ++ +N+ L +A T + V V+   
Sbjct: 946  SKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQVRVTVFPSK 1005

Query: 936  MAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDR 995
                  GVPWW+IL+A+LAG+L+LALLV +LWK GFFKR+++ + +VP+YHAV+I +E+R
Sbjct: 1006 TVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRSRYDD-SVPRYHAVRIRKEER 1064

Query: 996  QQFKEEKTGTILRNNW 1011
            +   E+    + +  W
Sbjct: 1065 EIKDEKYIDNLEKKQW 1080


>gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [Homo
            sapiens]
          Length = 1073

 Score =  902 bits (2331), Expect = 0.0
 Identities = 465/957 (48%), Positives = 644/957 (67%), Gaps = 35/957 (3%)

Query: 42   TCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQ 101
            TCAHRYE RQ V+   E+RD+ GRC+VLSQ+L I D++DGG+W FC+GR +GHE+FG CQ
Sbjct: 130  TCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLRGHEKFGSCQ 189

Query: 102  QGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRL 161
            QG AA F+ D HY++FGAPGTYNWKG  RVE       D+   +DGPYE GGE E D  L
Sbjct: 190  QGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVGGETEHDESL 249

Query: 162  IPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKD-SASRLVPEVMLSG 220
            +PVPANSY GFS+DSGKG+V  +E++FV+GAPRANH GAVV+L++D  ++ L+PE +  G
Sbjct: 250  VPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAHLLPEHIFDG 309

Query: 221  ERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRL 280
            E L S FGY +AV DLN DGW D+++GAP +F+R  E+GGAVYVY+NQ G W  + P+RL
Sbjct: 310  EGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGRWNNVKPIRL 369

Query: 281  CGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEA 340
             G+ DSMFGI++  +GD+NQDG+PDIAVGAP+D  GKVFIYHGS+ G+  KP+QVL+G +
Sbjct: 370  NGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTKPTQVLKGIS 429

Query: 341  VGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQP 400
                 FGYS++G++D+D N YPD+ VGSL+D+  +FR+RP++++   +++ P  IDL Q 
Sbjct: 430  ---PYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVTPNRIDLRQK 486

Query: 401  NCAGGHS-VCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEE 459
               G  S +C+ ++ CF Y A P+ Y+P++++   L+A+ +RR  G   RV F ++   E
Sbjct: 487  TACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRVQFRNQG-SE 545

Query: 460  PKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLP 519
            PK+    T  LK Q  +VC +    LQ+N++DKLR I +T S  +Q P  RR+     LP
Sbjct: 546  PKYTQELT--LKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSRRRV--NSLP 601

Query: 520  PVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTE-FQPLPMDVD 578
             V PILN+ +P T   ++HFLK+GCG+D +C SNL+L   +FCTR  + + F  LP+   
Sbjct: 602  EVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKL-EYKFCTREGNQDKFSYLPIQ-K 659

Query: 579  GTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALD- 637
            G   L  L  Q  I LE+ VTN PS+P  P  DGDDAHEA+L+   PD+L YS  R L  
Sbjct: 660  GVPEL-VLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLTYSAYRELRA 718

Query: 638  -PAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISE 696
             P ++  C++N+N S  +CELGNP KR + VTFYL+LST+ ++ +T +L++ L L T S 
Sbjct: 719  FPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDINLKLETTSN 778

Query: 697  QE-LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSN 755
            Q+ L P++A+A+V IEL LS++G+A P Q++F G V GE+AM+SE +VGS ++YE  V N
Sbjct: 779  QDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSLIEYEFRVIN 838

Query: 756  QGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDS 815
             G+ L  LG+A LNI WP EI+NGKWLLY ++VE +G     +K  C P+  I  L++  
Sbjct: 839  LGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKG----LEKVTCEPQKEINSLNLTE 894

Query: 816  RDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFD 875
                R++ E  E+Q    R+         S   ++K  TL+C+    NCV   CPL   D
Sbjct: 895  SHNSRKKREITEKQIDDNRK--------FSLFAERKYQTLNCS-VNVNCVNIRCPLRGLD 945

Query: 876  RAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDP 935
              A L +  RLWNSTFLEEYS +  L++++RA I V ++ +N+ L +A T + V V+   
Sbjct: 946  SKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQVRVTVFPSK 1005

Query: 936  MAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK--HPEATVPQYHAVKI 990
                  GVPWW+IL+A+LAG+L+LALLV +LWK GFFKR K  H +AT   YH  +I
Sbjct: 1006 TVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRNKKDHYDAT---YHKAEI 1059


>gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]
          Length = 1066

 Score =  531 bits (1369), Expect = e-150
 Identities = 350/979 (35%), Positives = 532/979 (54%), Gaps = 103/979 (10%)

Query: 43   CAHRYEARQRVDQIL-----ETRDMIGRCFVLSQDLAIRDELDGGEW--KFCEGRPQGHE 95
            CAHRY       Q+L     + R M+G+C+V   DL +    D   +  + C      + 
Sbjct: 140  CAHRYT------QVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTYHNEMCNSNTD-YL 192

Query: 96   QFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEK 155
            + G CQ GT+  F+ ++ Y  FGAPG YNWKG + +            +    ++     
Sbjct: 193  ETGMCQLGTSGGFTQNTVY--FGAPGAYNWKGNSYM------------IQRKEWDLSEYS 238

Query: 156  EQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPE 215
             +DP       N Y G+++  G  ++  + ++ V GAPR  H GAV +L +++   L   
Sbjct: 239  YKDPE---DQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRR 295

Query: 216  VMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGI 275
             +L G ++ + FG ++A+ADLN+DGW DL+VGAPY+FER+EE+GGA+YV++NQ G     
Sbjct: 296  QVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPA 355

Query: 276  SP-LRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQ 334
             P L L G   S FG+S+A +GD+NQDGF DIAVGAPF+G GKV+IYH SS G++ +P Q
Sbjct: 356  HPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQ 415

Query: 335  VLEGEAV---GIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIA 391
            V+ GE +   G+ +FGYSLSG +D+D N YPDLLVGSL+D  VL RARP++++ H+ ++ 
Sbjct: 416  VIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHK-TLV 474

Query: 392  PRSIDLEQPNCAGGHSVCVDLRVCFSY--IAVPSSYSPTVALDYVLDADTDRRLRGQVPR 449
            PR   L+   C    + CV + +CF+Y   A   +Y   + L Y L+AD DRR     PR
Sbjct: 475  PRPAVLDPALCTA--TSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRR----PPR 528

Query: 450  VTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRL 509
            + F          +++         +  C      L +N++DKLR I+++++YSL     
Sbjct: 529  LRFAG-------SESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMP 581

Query: 510  RRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTE 569
             R   G       PILN  Q      E+ F K+ CG D  C+SNLQ+ RA F +     +
Sbjct: 582  DRPRLGLRSLDAYPILNQAQALENHTEVQFQKE-CGPDNKCESNLQM-RAAFVSE-QQQK 638

Query: 570  FQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLH 629
               L    D    L          L + VTN  +     +  G+DAHEA L +++P +L 
Sbjct: 639  LSRLQYSRDVRKLL----------LSINVTNTRTS----ERSGEDAHEALLTLVVPPALL 684

Query: 630  YSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVEL 689
             S VR         C +NE    + CELGNP KR  ++   +     G+++ T +L+V+L
Sbjct: 685  LSSVR-----PPGACQANET---IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQL 736

Query: 690  LLATISEQE-LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVK 748
             L+T S Q+ L P+     V   L  S++ +    Q FF G V GE  M++  DVGS +K
Sbjct: 737  QLSTSSHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLK 796

Query: 749  YEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEG-GQGPGQKGLCSPRPN 807
            YE  V   G+ L  LG+  L + WP+E++NGKWLLYP ++ + G G  P     C P  +
Sbjct: 797  YEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWP-----CRPPGD 851

Query: 808  ILH-LDV---------DSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNIT-LD 856
            +++ L++          S  RRRR+L+P   Q P     P ++   +++A+K K+ T L 
Sbjct: 852  LINPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGP-----PPVT---LAAAKKAKSETVLT 903

Query: 857  CARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIK 916
            CA G A+CV   CP+        + V  R+WNSTF+E+Y     + V   A + +++SI 
Sbjct: 904  CATGRAHCVWLECPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIP 963

Query: 917  NLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK 976
             + + + +T   V +  + +  +   +  W++L+AV AGLL+L L++LLLWK  FFKR +
Sbjct: 964  TINMENKTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCDFFKRTR 1023

Query: 977  HPEATVPQYHAVKIPREDR 995
            + +  +P+YHAV+I  E+R
Sbjct: 1024 YYQ-IMPKYHAVRIREEER 1041


>gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]
          Length = 1051

 Score =  522 bits (1344), Expect = e-148
 Identities = 344/960 (35%), Positives = 520/960 (54%), Gaps = 102/960 (10%)

Query: 43   CAHRYEARQRVDQIL-----ETRDMIGRCFVLSQDLAIRDELDGGEW--KFCEGRPQGHE 95
            CAHRY       Q+L     + R M+G+C+V   DL +    D   +  + C      + 
Sbjct: 140  CAHRYT------QVLWSGSEDQRRMVGKCYVRGNDLELDSSDDWQTYHNEMCNSNTD-YL 192

Query: 96   QFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEK 155
            + G CQ GT+  F+ ++ Y  FGAPG YNWKG + +            +    ++     
Sbjct: 193  ETGMCQLGTSGGFTQNTVY--FGAPGAYNWKGNSYM------------IQRKEWDLSEYS 238

Query: 156  EQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPE 215
             +DP       N Y G+++  G  ++  + ++ V GAPR  H GAV +L +++   L   
Sbjct: 239  YKDPE---DQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRR 295

Query: 216  VMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGI 275
             +L G ++ + FG ++A+ADLN+DGW DL+VGAPY+FER+EE+GGA+YV++NQ G     
Sbjct: 296  QVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPA 355

Query: 276  SP-LRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQ 334
             P L L G   S FG+S+A +GD+NQDGF DIAVGAPF+G GKV+IYH SS G++ +P Q
Sbjct: 356  HPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQ 415

Query: 335  VLEGEAV---GIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIA 391
            V+ GE +   G+ +FGYSLSG +D+D N YPDLLVGSL+D  VL RARP++++ H+ ++ 
Sbjct: 416  VIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHK-TLV 474

Query: 392  PRSIDLEQPNCAGGHSVCVDLRVCFSY--IAVPSSYSPTVALDYVLDADTDRRLRGQVPR 449
            PR   L+   C    + CV + +CF+Y   A   +Y   + L Y L+AD DRR     PR
Sbjct: 475  PRPAVLDPALCTA--TSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRR----PPR 528

Query: 450  VTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRL 509
            + F          +++         +  C      L +N++DKLR I+++++YSL     
Sbjct: 529  LRFAG-------SESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMP 581

Query: 510  RRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTE 569
             R   G       PILN  Q      E+ F K+ CG D  C+SNLQ+ RA F +     +
Sbjct: 582  DRPRLGLRSLDAYPILNQAQALENHTEVQFQKE-CGPDNKCESNLQM-RAAFVSE-QQQK 638

Query: 570  FQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLH 629
               L    D    L          L + VTN  +     +  G+DAHEA L +++P +L 
Sbjct: 639  LSRLQYSRDVRKLL----------LSINVTNTRTS----ERSGEDAHEALLTLVVPPALL 684

Query: 630  YSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVEL 689
             S VR         C +NE    + CELGNP KR  ++   +     G+++ T +L+V+L
Sbjct: 685  LSSVR-----PPGACQANET---IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQL 736

Query: 690  LLATISEQE-LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVK 748
             L+T S Q+ L P+     V   L  S++ +    Q FF G V GE  M++  DVGS +K
Sbjct: 737  QLSTSSHQDNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLK 796

Query: 749  YEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEG-GQGPGQKGLCSPRPN 807
            YE  V   G+ L  LG+  L + WP+E++NGKWLLYP ++ + G G  P     C P  +
Sbjct: 797  YEFQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWP-----CRPPGD 851

Query: 808  ILH-LDV---------DSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNIT-LD 856
            +++ L++          S  RRRR+L+P   Q P     P ++   +++A+K K+ T L 
Sbjct: 852  LINPLNLTLSDPGDRPSSPQRRRRQLDPGGGQGP-----PPVT---LAAAKKAKSETVLT 903

Query: 857  CARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIK 916
            CA G A+CV   CP+        + V  R+WNSTF+E+Y     + V   A + +++SI 
Sbjct: 904  CATGRAHCVWLECPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIP 963

Query: 917  NLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK 976
             + + + +T   V +  + +  +   +  W++L+AV AGLL+L L++LLLWK GFFKRA+
Sbjct: 964  TINMENKTTWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRAR 1023


>gi|49170034 integrin, alpha 8 [Homo sapiens]
          Length = 1063

 Score =  304 bits (779), Expect = 3e-82
 Identities = 292/996 (29%), Positives = 460/996 (46%), Gaps = 152/996 (15%)

Query: 60   RDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGA 119
            +D +G C+V  Q+ +        E+  C       E  G+CQ G +  F  +   L+ G 
Sbjct: 165  KDPVGTCYVAIQNFSAY-----AEFSPCRNSNADPEGQGYCQAGFSLDFYKNGD-LIVGG 218

Query: 120  PGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPAN---SYFGFSIDS 176
            PG++ W+G       A   A+ +   D   +  GEK+ +      PA+   SY G+S+ +
Sbjct: 219  PGSFYWQGQVITASVADIIANYS-FKDILRKLAGEKQTEV----APASYDDSYLGYSVAA 273

Query: 177  GKGLVRAEELSFVAGAPR-ANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVAD 235
            G+    +++   VAG PR A + G V I+     + +      +GE++ S FGY++ V+D
Sbjct: 274  GEFTGDSQQ-ELVAGIPRGAQNFGYVSIINSTDMTFIQN---FTGEQMASYFGYTVVVSD 329

Query: 236  LNSDGWPDLIVGAPYFFERQEELG----GAVYVYLNQGGHWAGISPLRLCGSPD-SMFGI 290
            +NSDG  D++VGAP F ER+ E      G +Y+YL Q        P  L G+     FG 
Sbjct: 330  VNSDGLDDVLVGAPLFMEREFESNPREVGQIYLYL-QVSSLLFRDPQILTGTETFGRFGS 388

Query: 291  SLAVLGDLNQDGFPDIAVGAPFDGD---GKVFIYHGSSLGVVAKPSQVLEG----EAVGI 343
            ++A LGDLNQDG+ DIA+G PF G    GKV IY+G+  G+  KPSQVL+G     AV  
Sbjct: 389  AMAHLGDLNQDGYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTKPSQVLQGVWASHAVP- 447

Query: 344  KSFGYSLSGSLDMDGNQYPDLLVGSLADTAV-LFRARPILHVSHEVSIAPRSIDLEQPNC 402
              FG++L G  D+D N YPDL+VG+     V ++RARP++ V  ++ + P  I+LE   C
Sbjct: 448  SGFGFTLRGDSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQLLLHPMIINLENKTC 507

Query: 403  AGGHSV----CVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLE 458
                S+    C  LRVC S      S + T+ L   +  D+ ++ +G + R  FL     
Sbjct: 508  QVPDSMTSAACFSLRVCAS--VTGQSIANTIVLMAEVQLDSLKQ-KGAIKRTLFLD---- 560

Query: 459  EPKHQASGT--VWLKHQHDRVCGDAMFQLQENV--KDKLRAIVVTLSYSLQTPRLRRQAP 514
               HQA     + +K Q    C D +  L++    +DKL  I ++L+YSL     +    
Sbjct: 561  --NHQAHRVFPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLNYSLDESTFK---- 614

Query: 515  GQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLP 574
             +GL  V PILN ++ +    + H L   CGED +C  +L+L                  
Sbjct: 615  -EGL-EVKPILNYYRENIVSEQAHILVD-CGEDNLCVPDLKL------------------ 653

Query: 575  MDVDGTTALFALSGQPVIGLE---LMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYS 631
                   +      Q +IG E   +++ N        + +G+ A+EA+L VM+P+   Y 
Sbjct: 654  -------SARPDKHQVIIGDENHLMLIIN-------ARNEGEGAYEAELFVMIPEEADYV 699

Query: 632  GVRALDPAEKPLC--LSNENASH-VECELGNPMKRGAQVTFYLILSTSGISIETTELEVE 688
            G+   +   +PL      EN +  V C+LGNPM  G   +  L  +     +E T + + 
Sbjct: 700  GIERNNKGFRPLSCEYKMENVTRMVVCDLGNPMVSGTNYSLGLRFAVP--RLEKTNMSIN 757

Query: 689  LLLATISEQELHP----VSARARVFIELPLSIAGMAIPQQLFFS-GVVRGERAMQSERDV 743
              L   S  + +P    VS +  +     + I G++ P Q+         E     E +V
Sbjct: 758  FDLQIRSSNKDNPDSNFVSLQINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEV 817

Query: 744  GSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCS 803
            G  V++   + N G S  T+    L + WP   A  ++LLY   ++     GP Q   C 
Sbjct: 818  GPLVEHIYELHNIGPS--TISDTILEVGWPFS-ARDEFLLYIFHIQT---LGPLQ---CQ 868

Query: 804  PRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNI---------- 853
            P PNI            ++++P    E        +    +    +K+++          
Sbjct: 869  PNPNI----------NPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVEFHRQSP 918

Query: 854  --TLDCARGTANCVVFSCPLYSFD--RAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANI 909
               L+C      C+  SC +   +   +AVL V  RLW  TFL+  +   +L  +V   +
Sbjct: 919  AKILNCT--NIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKNDPYALASLVSFEV 976

Query: 910  -TVKSSIKNLMLRDASTVIPV-MVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLW 967
              +  + +   L + S  I   +++  P   V+  +P WVI+LA+L GLLVLA+L L LW
Sbjct: 977  KKMPYTDQPAKLPEGSIAIKTSVIWATPN--VSFSIPLWVIILAILLGLLVLAILTLALW 1034

Query: 968  KMGFFKRAKHPEATVPQYHAVKIPREDRQQFKEEKT 1003
            K GFF RA+ P+  +           DR+Q   +KT
Sbjct: 1035 KCGFFDRARPPQEDM----------TDREQLTNDKT 1060


>gi|52485941 integrin, alpha 9 precursor [Homo sapiens]
          Length = 1035

 Score =  277 bits (709), Expect = 3e-74
 Identities = 272/969 (28%), Positives = 456/969 (47%), Gaps = 138/969 (14%)

Query: 43   CAHRYE-ARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFC--EGRPQGHEQFGF 99
            CAHR++      D IL      G C+++  +L  +    G     C  E + +  E+ G 
Sbjct: 142  CAHRWKNIYYEADHILPH----GFCYIIPSNLQAK----GRTLIPCYEEYKKKYGEEHGS 193

Query: 100  CQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDP 159
            CQ G A  F+ +   ++ GAPG++ W GT +V           +L D  Y      + + 
Sbjct: 194  CQAGIAGFFTEE--LVVMGAPGSFYWAGTIKV----------LNLTDNTY-----LKLND 236

Query: 160  RLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSAS-RLVPEVML 218
             +I     +Y G+++ +G        +  V GAP+    G V I R D  S  L+     
Sbjct: 237  EVIMNRRYTYLGYAVTAGH-FSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQA 295

Query: 219  SGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQG-GHWAGISP 277
            SG+++ S FG SL   DLN DG  DL+VGAP F E ++E  G V VY+N+G G       
Sbjct: 296  SGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSEIRDE--GQVTVYINRGNGALEEQLA 353

Query: 278  LRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSSLGVVAKPSQV 335
            L   G+ ++ FG S+A L DL+ DGFPD+A+GAP + D  G V+IYHG + G+V + S  
Sbjct: 354  LTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIVPQYSMK 413

Query: 336  LEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGS-LADTAVLFRARPILHVSHEVSI-A 391
            L G+ +   ++ FG S+SG +DMDGN YPD+ VG+ ++D+ VL RARP++ V  +VSI  
Sbjct: 414  LSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITV--DVSIFL 471

Query: 392  PRSIDLEQPNCAGGHSV--CVDLRVCFSYIA--VPSSYSPTVALDYVLDADTDRRLRGQV 447
            P SI++  P C  G     C+++  CFS+    VP      + L+YVL AD  ++ +GQ+
Sbjct: 472  PGSINITAPQCHDGQQPVNCLNVTTCFSFHGKHVPGE----IGLNYVLMADVAKKEKGQM 527

Query: 448  PRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTP 507
            PRV F+   L E   Q +  + L +  +  C   +  ++  V+D +  IV   +YSL   
Sbjct: 528  PRVYFVL--LGETMGQVTEKLQLTYM-EETCRHYVAHVKRRVQDVISPIVFEAAYSLSEH 584

Query: 508  RLRRQAPGQGLPPVAPIL--NAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRV 565
                +   + LPP+ P+L     Q   Q+ +  F +    ED  C ++LQL         
Sbjct: 585  VTGEEE--RELPPLTPVLRWKKGQKIAQKNQTVFERNCRSED--CAADLQL--------- 631

Query: 566  SDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLP 625
               + + L   +D  T   AL     I L + ++NL          GDDA++A +   + 
Sbjct: 632  ---QGKLLLSSMDEKTLYLALGAVKNISLNISISNL----------GDDAYDANVSFNVS 678

Query: 626  DSLHYSGVRALDPAEKPLCLSNENASHVECELGNP-MKRGAQVTFYLILSTSGISIETTE 684
              L +  +      E  +      +  ++C +G P M+  ++  F +I  TS +S E   
Sbjct: 679  RELFF--INMWQKEEMGISCELLESDFLKCSVGFPFMRSKSKYEFSVIFDTSHLSGEEEV 736

Query: 685  LEVELLLATISEQELHPVSARARVFI-----ELPLSIAGMAIPQQLFFSGVVRGERAMQS 739
            L   +   + + +    +     V +     E+  SI G+  P    +   V     +Q 
Sbjct: 737  LSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQL 796

Query: 740  ERDVG---SKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGP 796
            + D+      +   + V N G S  TL  + ++I +P+ +++G   ++ +Q E+  GQ  
Sbjct: 797  D-DLECHFQPINITLQVYNTGPS--TLPGSSVSISFPNRLSSGGAEMFHVQ-EMVVGQ-- 850

Query: 797  GQKGLCS----PRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKN 852
             +KG CS    P P I+                P++QE       ++     +   K   
Sbjct: 851  -EKGNCSFQKNPTPCII----------------PQEQE-------NIFHTIFAFFTKSGR 886

Query: 853  ITLDCARGTANCVVFSCPLYSF--DRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANIT 910
              LDC +   +C+   C   +   + +  + ++  L N+  L++ S+   ++ + RA + 
Sbjct: 887  KVLDCEKPGISCLTAHCNFSALAKEESRTIDIY-MLLNTEILKKDSS-SVIQFMSRAKVK 944

Query: 911  VKSSIKNLML-----RDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLL 965
            V  +++ + +      + + V   +  L+P   V      W+I +++L G+L+  LL +L
Sbjct: 945  VDPALRVVEIAHGNPEEVTVVFEALHNLEPRGYVV----GWIIAISLLVGILIFLLLAVL 1000

Query: 966  LWKMGFFKR 974
            LWKMGFF+R
Sbjct: 1001 LWKMGFFRR 1009


>gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]
          Length = 1002

 Score =  276 bits (707), Expect = 6e-74
 Identities = 272/977 (27%), Positives = 451/977 (46%), Gaps = 126/977 (12%)

Query: 43  CAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQ 102
           CA  Y  R  + Q    R+ +G CF       ++D     E+  C  +    +  GFCQ 
Sbjct: 92  CAPLYHWRTEMKQ---EREPVGTCF-------LQDGTKTVEYAPCRSQDIDADGQGFCQG 141

Query: 103 GTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLI 162
           G +  F+     LL G PG++ W+G     +  Q +  ++  D   Y      +   R  
Sbjct: 142 GFSIDFTKADRVLL-GGPGSFYWQGQL---ISDQVAEIVSKYDPNVYSIKYNNQLATRTA 197

Query: 163 P-VPANSYFGFSID----SGKGLVRAEELSFVAGAPRANHK-GAVVILRKDSASRLVPEV 216
             +  +SY G+S+     +G G+       FV+G PRA    G V I    + S L    
Sbjct: 198 QAIFDDSYLGYSVAVGDFNGDGID-----DFVSGVPRAARTLGMVYIYDGKNMSSLYN-- 250

Query: 217 MLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELG----GAVYVYLNQGGHW 272
             +GE++ + FG+S+A  D+N D + D+ +GAP F +R  +      G V V L +    
Sbjct: 251 -FTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRAS-- 307

Query: 273 AGISPLRLCG-SPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGK---VFIYHGSSLGV 328
                 +L G    + FG ++A LGDL+QDGF DIA+ AP+ G+ K   V+I++G S G+
Sbjct: 308 GDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGL 367

Query: 329 VAKPSQVLEGEAVGIK---SFGYSLSGSLDMDGNQYPDLLVGSL-ADTAVLFRARPILHV 384
            A PSQ+LEG+        SFGYS+ G+ D+D N YPDL+VG+   D A+L+RARP++ V
Sbjct: 368 NAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITV 427

Query: 385 SHEVSIAPRSIDLEQPNCAGGHSV----CVDLRVCFSYIAVPSSYSPTVALDYVLDADTD 440
           +  + + P  ++ +   C+   +     C ++R C    A      P   L++ ++   D
Sbjct: 428 NAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLK--ADGKGVLPR-KLNFQVELLLD 484

Query: 441 R-RLRGQVPRVTFL-SRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVV 498
           + + +G + R  FL SR+    K+       L    + +   A  + +   +DKL  I +
Sbjct: 485 KLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELI---AYLRDESEFRDKLTPITI 541

Query: 499 TLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVR 558
            + Y L     R  A   GL    PILN   P+    + H L   CGED +C+  L++  
Sbjct: 542 FMEYRLD---YRTAADTTGL---QPILNQFTPANISRQAHILLD-CGEDNVCKPKLEV-- 592

Query: 559 ARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEA 618
                   D++ + + +  D    L                       + Q  G+ A+EA
Sbjct: 593 ------SVDSDQKKIYIGDDNPLTLI---------------------VKAQNQGEGAYEA 625

Query: 619 QLLVMLPDSLHYSGVRALDPAEKPL--CLSNENAS-HVECELGNPMKRGAQVTFYLILST 675
           +L+V +P    + GV   + A   L      EN +  V C+LGNPMK G Q+   L  S 
Sbjct: 626 ELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSV 685

Query: 676 SGISIETTELEVELLL--ATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRG 733
              S   T ++ +L +  + + ++    VS +  + +   + I G++ P  +F   +   
Sbjct: 686 HQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLP-IPNW 744

Query: 734 ERA--MQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELE 791
           E     ++E DVG  V++   + N G S  +   A L++ WP++  N   LLY +  +++
Sbjct: 745 EHKENPETEEDVGPVVQHIYELRNNGPS--SFSKAMLHLQWPYKY-NNNTLLYILHYDID 801

Query: 792 GGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQE--PGERQEPSMSWWPVSSAEK 849
           G           P      ++++    +   L+  E+ +   G+ +   +      +  +
Sbjct: 802 G-----------PMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSE 850

Query: 850 KKNITLDCARGTANCVVFSCPLYSFDR--AAVLHVWGRLWNSTFLEEYSAVKSLEVIVRA 907
               TL C  G A C+   C +   DR  +A+L+V   LW  TF+ + +   S  +   A
Sbjct: 851 GDIHTLGC--GVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSA 908

Query: 908 NITV-KSSIKNLMLRDA--STVIPVMVY--LDPMAVVAEGVPWWVILLAVLAGLLVLALL 962
           +  V +   KNL + D   ST++   V   + P  +    VP WVI+LAVLAGLL+LA+L
Sbjct: 909 SFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPM---PVPVWVIILAVLAGLLLLAVL 965

Query: 963 VLLLWKMGFFKRAKHPE 979
           V ++++MGFFKR + P+
Sbjct: 966 VFVMYRMGFFKRVRPPQ 982


>gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]
          Length = 1048

 Score =  276 bits (707), Expect = 6e-74
 Identities = 272/977 (27%), Positives = 451/977 (46%), Gaps = 126/977 (12%)

Query: 43   CAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQ 102
            CA  Y  R  + Q    R+ +G CF       ++D     E+  C  +    +  GFCQ 
Sbjct: 138  CAPLYHWRTEMKQ---EREPVGTCF-------LQDGTKTVEYAPCRSQDIDADGQGFCQG 187

Query: 103  GTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLI 162
            G +  F+     LL G PG++ W+G     +  Q +  ++  D   Y      +   R  
Sbjct: 188  GFSIDFTKADRVLL-GGPGSFYWQGQL---ISDQVAEIVSKYDPNVYSIKYNNQLATRTA 243

Query: 163  P-VPANSYFGFSID----SGKGLVRAEELSFVAGAPRANHK-GAVVILRKDSASRLVPEV 216
              +  +SY G+S+     +G G+       FV+G PRA    G V I    + S L    
Sbjct: 244  QAIFDDSYLGYSVAVGDFNGDGID-----DFVSGVPRAARTLGMVYIYDGKNMSSLYN-- 296

Query: 217  MLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELG----GAVYVYLNQGGHW 272
              +GE++ + FG+S+A  D+N D + D+ +GAP F +R  +      G V V L +    
Sbjct: 297  -FTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRAS-- 353

Query: 273  AGISPLRLCG-SPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGK---VFIYHGSSLGV 328
                  +L G    + FG ++A LGDL+QDGF DIA+ AP+ G+ K   V+I++G S G+
Sbjct: 354  GDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGL 413

Query: 329  VAKPSQVLEGEAVGIK---SFGYSLSGSLDMDGNQYPDLLVGSL-ADTAVLFRARPILHV 384
             A PSQ+LEG+        SFGYS+ G+ D+D N YPDL+VG+   D A+L+RARP++ V
Sbjct: 414  NAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITV 473

Query: 385  SHEVSIAPRSIDLEQPNCAGGHSV----CVDLRVCFSYIAVPSSYSPTVALDYVLDADTD 440
            +  + + P  ++ +   C+   +     C ++R C    A      P   L++ ++   D
Sbjct: 474  NAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLK--ADGKGVLPR-KLNFQVELLLD 530

Query: 441  R-RLRGQVPRVTFL-SRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVV 498
            + + +G + R  FL SR+    K+       L    + +   A  + +   +DKL  I +
Sbjct: 531  KLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELI---AYLRDESEFRDKLTPITI 587

Query: 499  TLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVR 558
             + Y L     R  A   GL    PILN   P+    + H L   CGED +C+  L++  
Sbjct: 588  FMEYRLD---YRTAADTTGL---QPILNQFTPANISRQAHILLD-CGEDNVCKPKLEV-- 638

Query: 559  ARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEA 618
                    D++ + + +  D    L                       + Q  G+ A+EA
Sbjct: 639  ------SVDSDQKKIYIGDDNPLTLI---------------------VKAQNQGEGAYEA 671

Query: 619  QLLVMLPDSLHYSGVRALDPAEKPL--CLSNENAS-HVECELGNPMKRGAQVTFYLILST 675
            +L+V +P    + GV   + A   L      EN +  V C+LGNPMK G Q+   L  S 
Sbjct: 672  ELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSV 731

Query: 676  SGISIETTELEVELLL--ATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRG 733
               S   T ++ +L +  + + ++    VS +  + +   + I G++ P  +F   +   
Sbjct: 732  HQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLP-IPNW 790

Query: 734  ERA--MQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELE 791
            E     ++E DVG  V++   + N G S  +   A L++ WP++  N   LLY +  +++
Sbjct: 791  EHKENPETEEDVGPVVQHIYELRNNGPS--SFSKAMLHLQWPYKY-NNNTLLYILHYDID 847

Query: 792  GGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQE--PGERQEPSMSWWPVSSAEK 849
            G           P      ++++    +   L+  E+ +   G+ +   +      +  +
Sbjct: 848  G-----------PMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSE 896

Query: 850  KKNITLDCARGTANCVVFSCPLYSFDR--AAVLHVWGRLWNSTFLEEYSAVKSLEVIVRA 907
                TL C  G A C+   C +   DR  +A+L+V   LW  TF+ + +   S  +   A
Sbjct: 897  GDIHTLGC--GVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSA 954

Query: 908  NITV-KSSIKNLMLRDA--STVIPVMVY--LDPMAVVAEGVPWWVILLAVLAGLLVLALL 962
            +  V +   KNL + D   ST++   V   + P  +    VP WVI+LAVLAGLL+LA+L
Sbjct: 955  SFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPM---PVPVWVIILAVLAGLLLLAVL 1011

Query: 963  VLLLWKMGFFKRAKHPE 979
            V ++++MGFFKR + P+
Sbjct: 1012 VFVMYRMGFFKRVRPPQ 1028


>gi|56237029 integrin alpha 5 precursor [Homo sapiens]
          Length = 1049

 Score =  256 bits (655), Expect = 6e-68
 Identities = 285/991 (28%), Positives = 439/991 (44%), Gaps = 144/991 (14%)

Query: 43   CAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQ 102
            CA  Y  R   + +    D +G C+ LS D   R      E+  C          G+CQ 
Sbjct: 156  CAPLYSWRTEKEPL---SDPVGTCY-LSTDNFTRIL----EYAPCRSDFSWAAGQGYCQG 207

Query: 103  GTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLI 162
            G +A F+     +L G PG+Y W+G  ++    Q     ++  +        + Q  +  
Sbjct: 208  GFSAEFTKTGRVVL-GGPGSYFWQG--QILSATQEQIAESYYPEYLINLVQGQLQTRQAS 264

Query: 163  PVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGER 222
             +  +SY G+S+  G+      E  FVAG P+ N     V +   S  R +     SGE+
Sbjct: 265  SIYDDSYLGYSVAVGEFSGDDTE-DFVAGVPKGNLTYGYVTILNGSDIRSLYN--FSGEQ 321

Query: 223  LTSGFGYSLAVADLNSDGWPDLIVGAPYFFER----QEELGGAVYVYLNQGGHWAGISP- 277
            + S FGY++A  D+N DG  DL+VGAP   +R    + +  G VYVYL    H AGI P 
Sbjct: 322  MASYFGYAVAATDVNGDGLDDLLVGAPLLMDRTPDGRPQEVGRVYVYLQ---HPAGIEPT 378

Query: 278  --LRLCGSPD-SMFGISLAVLGDLNQDGFPDIAVGAPFDGD---GKVFIYHGSSLGVVAK 331
              L L G  +   FG SL  LGDL+QDG+ D+A+GAPF G+   G VF++ G   G+ +K
Sbjct: 379  PTLTLTGHDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGETQQGVVFVFPGGPGGLGSK 438

Query: 332  PSQVLEGEAVGIKS---FGYSLSGSLDMDGNQYPDLLVGSLA-DTAVLFRARPILHVSHE 387
            PSQVL+       +   FG +L G  D+DGN YPDL+VGS   D AV++R RPI+  S  
Sbjct: 439  PSQVLQPLWAASHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYRGRPIVSASAS 498

Query: 388  VSIAPRSIDLEQPNCA--GGHSVCVDLRVCFS----YIAVPSSYSPTVALDYVLDADTDR 441
            ++I P   + E+ +C+  G    C++L  C +    ++A    ++  + LD+       +
Sbjct: 499  LTIFPAMFNPEERSCSLEGNPVACINLSFCLNASGKHVADSIGFTVELQLDW-------Q 551

Query: 442  RLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQL--QENVKDKLRAIVVT 499
            + +G V R  FL+      +   + T+ +++     C +    L  +   +DKL  I + 
Sbjct: 552  KQKGGVRRALFLASR----QATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSPIHIA 607

Query: 500  LSYSLQTPRLRRQAP--GQGLPPVAPILNAHQPSTQRAEIHF-LKQGCGEDKICQSNLQL 556
            L++SL       QAP    GL P       H  S  R E    +   CGED IC  +LQL
Sbjct: 608  LNFSLDP-----QAPVDSHGLRPAL-----HYQSKSRIEDKAQILLDCGEDNICVPDLQL 657

Query: 557  VRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAH 616
                               +V G      L  +  + L     N+             A+
Sbjct: 658  -------------------EVFGEQNHVYLGDKNALNLTFHAQNVGEG---------GAY 689

Query: 617  EAQLLVMLPDSLHYSG-VRALDPAEKPLC--LSNENASHVECELGNPMKRGAQVTFYLIL 673
            EA+L V  P    YSG VR         C   +   +  + C+LGNPMK GA +   L  
Sbjct: 690  EAELRVTAPPEAEYSGLVRHPGNFSSLSCDYFAVNQSRLLVCDLGNPMKAGASLWGGLRF 749

Query: 674  STSGI--SIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVV 731
            +   +  + +T + + ++L   ++  +   VS R  V  +  +++ G++ P+ + F    
Sbjct: 750  TVPHLRDTKKTIQFDFQILSKNLNNSQSDVVSFRLSVEAQAQVTLNGVSKPEAVLFPVSD 809

Query: 732  RGERAM-QSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVEL 790
               R   Q E D+G  V +   + NQG S  ++    L +  P  +  G+ LLY  +V  
Sbjct: 810  WHPRDQPQKEEDLGPAVHHVYELINQGPS--SISQGVLELSCPQAL-EGQQLLYVTRVT- 865

Query: 791  EGGQGPGQKGL-CSPR----PNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVS 845
                     GL C+      P  L LD +     +++ E P +                S
Sbjct: 866  ---------GLNCTTNHPINPKGLELDPEGSLHHQQKREAPSR----------------S 900

Query: 846  SAEKKKNITLDCARGTANCVVFSC---PLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSL- 901
            SA     I L C    A C    C   PL+  +  + L +  R+W  TFL+      SL 
Sbjct: 901  SASSGPQI-LKCPE--AECFRLRCELGPLHQQESQS-LQLHFRVWAKTFLQREHQPFSLQ 956

Query: 902  -EVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLA 960
             E + +A + +   I    L      +   V     A  + GVP W+I+LA+L GLL+L 
Sbjct: 957  CEAVYKA-LKMPYRILPRQLPQKERQVATAVQWTK-AEGSYGVPLWIIILAILFGLLLLG 1014

Query: 961  LLVLLLWKMGFFKRAKHPEATVPQYHAVKIP 991
            LL+ +L+K+GFFKR+  P  T  +   +K P
Sbjct: 1015 LLIYILYKLGFFKRSL-PYGTAMEKAQLKPP 1044


>gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]
          Length = 1012

 Score =  256 bits (654), Expect = 8e-68
 Identities = 243/852 (28%), Positives = 403/852 (47%), Gaps = 111/852 (13%)

Query: 167 NSYFGFSID----SGKGLVRAEELSFVAGAPRANHK-GAVVILRKDSASRLVPEVMLSGE 221
           +SY G+S+     +G G+       FV+G PRA    G V I    + S L      +GE
Sbjct: 213 DSYLGYSVAVGDFNGDGID-----DFVSGVPRAARTLGMVYIYDGKNMSSLYN---FTGE 264

Query: 222 RLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELG----GAVYVYLNQGGHWAGISP 277
           ++ + FG+S+A  D+N D + D+ +GAP F +R  +      G V V L +         
Sbjct: 265 QMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRAS--GDFQT 322

Query: 278 LRLCG-SPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGK---VFIYHGSSLGVVAKPS 333
            +L G    + FG ++A LGDL+QDGF DIA+ AP+ G+ K   V+I++G S G+ A PS
Sbjct: 323 TKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPS 382

Query: 334 QVLEGEAVGIK---SFGYSLSGSLDMDGNQYPDLLVGSL-ADTAVLFRARPILHVSHEVS 389
           Q+LEG+        SFGYS+ G+ D+D N YPDL+VG+   D A+L+RARP++ V+  + 
Sbjct: 383 QILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLE 442

Query: 390 IAPRSIDLEQPNCAGGHSV----CVDLRVCFSYIAVPSSYSPTVALDYVLDADTDR-RLR 444
           + P  ++ +   C+   +     C ++R C    A      P   L++ ++   D+ + +
Sbjct: 443 VYPSILNQDNKTCSLPGTALKVSCFNVRFCLK--ADGKGVLPR-KLNFQVELLLDKLKQK 499

Query: 445 GQVPRVTFL-SRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYS 503
           G + R  FL SR+    K+       L    + +   A  + +   +DKL  I + + Y 
Sbjct: 500 GAIRRALFLYSRSPSHSKNMTISRGGLMQCEELI---AYLRDESEFRDKLTPITIFMEYR 556

Query: 504 LQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCT 563
           L     R  A   GL    PILN   P+    + H L   CGED +C+  L++       
Sbjct: 557 LD---YRTAADTTGL---QPILNQFTPANISRQAHILLD-CGEDNVCKPKLEV------- 602

Query: 564 RVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVM 623
              D++ + + +  D    L                       + Q  G+ A+EA+L+V 
Sbjct: 603 -SVDSDQKKIYIGDDNPLTLI---------------------VKAQNQGEGAYEAELIVS 640

Query: 624 LPDSLHYSGVRALDPAEKPL--CLSNENAS-HVECELGNPMKRGAQVTFYLILSTSGISI 680
           +P    + GV   + A   L      EN +  V C+LGNPMK G Q+   L  S    S 
Sbjct: 641 IPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDLGNPMKAGTQLLAGLRFSVHQQSE 700

Query: 681 ETTELEVELLL--ATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERA-- 736
             T ++ +L +  + + ++    VS +  + +   + I G++ P  +F   +   E    
Sbjct: 701 MDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVEIRGVSSPDHIFLP-IPNWEHKEN 759

Query: 737 MQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGP 796
            ++E DVG  V++   + N G S  +   A L++ WP++  N   LLY +  +++G    
Sbjct: 760 PETEEDVGPVVQHIYELRNNGPS--SFSKAMLHLQWPYKY-NNNTLLYILHYDIDG---- 812

Query: 797 GQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQE--PGERQEPSMSWWPVSSAEKKKNIT 854
                  P      ++++    +   L+  E+ +   G+ +   +      +  +    T
Sbjct: 813 -------PMNCTSDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHT 865

Query: 855 LDCARGTANCVVFSCPLYSFDR--AAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITV- 911
           L C  G A C+   C +   DR  +A+L+V   LW  TF+ + +   S  +   A+  V 
Sbjct: 866 LGC--GVAQCLKIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSYSLKSSASFNVI 923

Query: 912 KSSIKNLMLRDA--STVIPVMVY--LDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLW 967
           +   KNL + D   ST++   V   + P  +    VP WVI+LAVLAGLL+LA+LV +++
Sbjct: 924 EFPYKNLPIEDITNSTLVTTNVTWGIQPAPM---PVPVWVIILAVLAGLLLLAVLVFVMY 980

Query: 968 KMGFFKRAKHPE 979
           +MGFFKR + P+
Sbjct: 981 RMGFFKRVRPPQ 992


>gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]
          Length = 1039

 Score =  246 bits (628), Expect = 8e-65
 Identities = 275/973 (28%), Positives = 434/973 (44%), Gaps = 157/973 (16%)

Query: 63   IGRCFVLSQDLAIRDELDGGEWKFCEG----RPQGHEQFGFCQQGTAAAFSP---DSHYL 115
            +G CF+   +   R      E+  C G    R      F + ++   A FS     +  L
Sbjct: 158  VGSCFLAQPESGRR-----AEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGEL 212

Query: 116  LFGAPGTYNWKGTARVELCAQGSADLAHLDDGP----YEAGGEKEQDPRLIPVPANSYFG 171
            + GAPG Y + G     L AQ           P    +    +        P   + Y+G
Sbjct: 213  VLGAPGGYYFLG-----LLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWG 267

Query: 172  FSIDSGKGLVRAEELSFVAGAPRANHK-GAVVILRKDSASRLVPEVMLSGERLTSGFGYS 230
            +S+  G+         +V GAP  +   GAV IL  DS  + +    L GE++ S FG+S
Sbjct: 268  YSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEIL--DSYYQRLHR--LRGEQMASYFGHS 323

Query: 231  LAVADLNSDGWPDLIVGAPYFFERQEELG----GAVYVYLN-QGGHWAGISPLRLCGSP- 284
            +AV D+N DG  DL+VGAP + E + +      G VY++L  +G H  G   L L G+  
Sbjct: 324  VAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQL 383

Query: 285  DSMFGISLAVLGDLNQDGFPDIAVGAPFDGD---GKVFIYHGSSLGVVAKPSQVLEGEAV 341
               FG ++A LGDL++DG+ DIAV AP+ G    G+V ++ G S G+ ++PSQVL+    
Sbjct: 384  YGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFP 443

Query: 342  GIKSFGYSLSGSLDMDGNQYPDLLVGSL-ADTAVLFRARPILHVSHEVSI------APRS 394
               +FG+SL G++D+D N YPDL+VG+  A+   ++RA+P++  S ++ +      A +S
Sbjct: 444  TGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKS 503

Query: 395  IDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLS 454
              L Q         C ++++C    A   +    ++L+  L  D  +  +G+  RV  L 
Sbjct: 504  CVLPQTKTPVS---CFNIQMCVG--ATGHNIPQKLSLNAELQLDRQKPRQGR--RVLLLG 556

Query: 455  RNLEEPKHQASGTVW---LKHQHDRVCGDAMFQLQE--NVKDKLRAIVVTLSYSLQTPRL 509
                    Q +GT     L  +H  +C   M  L++  + +DKL  IV++L+ SL  P  
Sbjct: 557  -------SQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSL-PPTE 608

Query: 510  RRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTE 569
               AP       A +L+      ++  I      CGED +C   LQL             
Sbjct: 609  AGMAP-------AVVLHGDTHVQEQTRIVL---DCGEDDVCVPQLQLTA----------- 647

Query: 570  FQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLH 629
                           +++G P++     V  L  D A    +G+ A+EA+L V LP   H
Sbjct: 648  ---------------SVTGSPLLVGADNVLELQMDAAN---EGEGAYEAELAVHLPQGAH 689

Query: 630  YSGVRAL---DPAEKPLC-LSNENASHVE-CELGNPMKRGAQVTFYLILSTSGISIETTE 684
            Y  +RAL   +  E+ +C    EN + V  CELGNPMK+ AQ+   +++S   +      
Sbjct: 690  Y--MRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGNLEEAGES 747

Query: 685  LEVELLLATISEQE------LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQ 738
            +  +L + + + Q       L  V  RA   +EL     G + P  L  +    GER   
Sbjct: 748  VSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVEL----RGNSFPASLVVA-AEEGEREQN 802

Query: 739  SERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGG----- 793
            S    G KV++   + N G    T+    L+I  P + +    LLY + ++ +GG     
Sbjct: 803  SLDSWGPKVEHTYELHNNGPG--TVNGLHLSIHLPGQ-SQPSDLLYILDIQPQGGLQCFP 859

Query: 794  QGPGQK-----GLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAE 848
            Q P        GL  P P+ +H     RDRR+  L  PE ++P   Q+P           
Sbjct: 860  QPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFL--PEPEQPSRLQDP----------- 906

Query: 849  KKKNITLDCARGTANCVVFSCPLYSFDRA--AVLHVWGRLWNSTFLEEYSAVKSLEVIVR 906
                + + C   +A C V  C L    R   A++ V   LW  +  +       L+    
Sbjct: 907  ----VLVSC--DSAPCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAW 960

Query: 907  ANI-TVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLL 965
             N+ ++  ++  L L      +   +     A+    +P W +L+ VL GLL+L +LVL 
Sbjct: 961  FNVSSLPYAVPPLSLPRGEAQVWTQLL---RALEERAIPIWWVLVGVLGGLLLLTILVLA 1017

Query: 966  LWKMGFFKRAKHP 978
            +WK+GFFKR + P
Sbjct: 1018 MWKVGFFKRNRPP 1030


>gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
          Length = 1179

 Score =  227 bits (578), Expect = 5e-59
 Identities = 242/914 (26%), Positives = 399/914 (43%), Gaps = 161/914 (17%)

Query: 101  QQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPR 160
            Q G +A +S D  +++ GA G Y+W GT  ++  +Q    +    +  +     K+ +P 
Sbjct: 379  QTGFSAHYSQD--WVMLGAVGAYDWNGTVVMQKASQ----IIIPRNTTFNVESTKKNEPL 432

Query: 161  LIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSG 220
                   SY G++++S      + ++ ++AG PR NH G V+I R +  +  + +  LSG
Sbjct: 433  A------SYLGYTVNSATA--SSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQT-LSG 483

Query: 221  ERLTSGFGYSLAVADLNSDGWPD-LIVGAPYFFERQEELGGAVYVY-LNQGG--HWAGIS 276
            E++ S FG  L   D++ D   D L+VGAP +   ++E  G VYVY LNQ    +   + 
Sbjct: 484  EQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLE 543

Query: 277  PLR--LCGSPD--------------SMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKV 318
            P++   C S                + FG ++A + DLN DGF DI +GAP + D  G V
Sbjct: 544  PIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAV 603

Query: 319  FIYHGSSLGVVAKPSQVLE--GEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLF 376
            +IYHGS   +  + +Q +   G+   +K FG S+ G +D++G+   D+ +G L   A LF
Sbjct: 604  YIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAA-LF 662

Query: 377  RARPILHVSHEVSIAPRSIDLEQPNC--AGGHSVCVDLRVCFSYIAVPSSYSPTVALDYV 434
             +R +  V   ++  P  +++++ NC   G  +VC++  VCF  + + S        D +
Sbjct: 663  WSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCINATVCFD-VKLKSKE------DTI 715

Query: 435  LDADTDRRLR----GQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVK 490
             +AD   R+      Q+ R  F     +E K Q + TV         C    F + +   
Sbjct: 716  YEADLQYRVTLDSLRQISRSFF--SGTQERKVQRNITV-----RKSECTKHSFYMLDK-H 767

Query: 491  DKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKIC 550
            D   ++ +TL ++L  P               P+L+   P++    I F K  CG  + C
Sbjct: 768  DFQDSVRITLDFNLTDPEN------------GPVLDDSLPNSVHEYIPFAKD-CGNKEKC 814

Query: 551  QSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQA 610
             S+L L        V+ TE             L   S      + L V N          
Sbjct: 815  ISDLSL-------HVATTE----------KDLLIVRSQNDKFNVSLTVKNTK-------- 849

Query: 611  DGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNP-MKRGAQVTF 669
              D A+  + +V    +L +SG+ A+   +K  C SN N   + C++G P ++RG  VTF
Sbjct: 850  --DSAYNTRTIVHYSPNLVFSGIEAI---QKDSCESNHN---ITCKVGYPFLRRGEMVTF 901

Query: 670  YLILSTSGISIETTEL--EVELLLATISEQELHP-------VSARARVFIELPLSIAGMA 720
             ++         T+ L   V + L+  S+ E  P       V+    V  E+ L     A
Sbjct: 902  KILFQ-----FNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSA 956

Query: 721  IPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGK 780
                +  +        + S  D+G+++     +   G     +    L+I +P+  +NG 
Sbjct: 957  SEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSF--PMPELKLSISFPNMTSNGY 1014

Query: 781  WLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMS 840
             +LYP       G    +   C  RP+I               E P     G++      
Sbjct: 1015 PVLYPT------GLSSSENANC--RPHIF--------------EDPFSINSGKKMT---- 1048

Query: 841  WWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKS 900
                S+   K+   LDC   T      +C L S D + V +V   LW  TF++ Y +  S
Sbjct: 1049 ---TSTDHLKRGTILDC--NTCKFATITCNLTSSDISQV-NVSLILWKPTFIKSYFS--S 1100

Query: 901  LEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLA 960
            L + +R  +  +++   L   +    + + +  D +      VP WVILL+  AGLL+L 
Sbjct: 1101 LNLTIRGELRSENASLVLSSSNQKRELAIQISKDGLP---GRVPLWVILLSAFAGLLLLM 1157

Query: 961  LLVLLLWKMGFFKR 974
            LL+L LWK+GFFKR
Sbjct: 1158 LLILALWKIGFFKR 1171


>gi|67191027 integrin alpha 4 precursor [Homo sapiens]
          Length = 1032

 Score =  199 bits (505), Expect = 1e-50
 Identities = 226/904 (25%), Positives = 389/904 (43%), Gaps = 113/904 (12%)

Query: 95   EQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGE 154
            E F  CQ G ++ ++ D   ++ GAPG+  W G+  V           ++    Y+A  +
Sbjct: 193  ENFASCQAGISSFYTKD--LIVMGAPGSSYWTGSLFVY----------NITTNKYKAFLD 240

Query: 155  KEQDPRLIPVPANSYFGFSIDSGKGLVRAEELS-FVAGAPRANHKGAVVILRKDSASRLV 213
            K+       V   SY G+S+  G G  R++  +  V GAP+    G   I   D     +
Sbjct: 241  KQNQ-----VKFGSYLGYSV--GAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNI 293

Query: 214  PEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQG-GHW 272
               M  G++L S FG S+   DLN+DG+ DL+VGAP     +EE  G V+VY+N G G  
Sbjct: 294  LHEM-KGKKLGSYFGASVCAVDLNADGFSDLLVGAPMQSTIREE--GRVFVYINSGSGAV 350

Query: 273  AGISPLRLCGSPD--SMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSSLGV 328
                   L GS    + FG S+  LGD++ DGF D+A+GAP + D  G ++IY+G + G+
Sbjct: 351  MNAMETNLVGSDKYAARFGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGI 410

Query: 329  VAKPSQVLEGEAV--GIKSFGYSLSGSLDMDGNQYPDLLVGSL-ADTAVLFRARPILHVS 385
             +  SQ +EG  +   +  FG S+SG +D D N Y D+ VG+  +D+AVL R RP++ V 
Sbjct: 411  SSTFSQRIEGLQISKSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVD 470

Query: 386  HEVSIAPRSIDLEQPNCA--GGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRL 443
              +S  P S++  + +C   G  SVC+DL +CFSY          + L Y +  D +R+ 
Sbjct: 471  ASLS-HPESVNRTKFDCVENGWPSVCIDLTLCFSYKG--KEVPGYIVLFYNMSLDVNRKA 527

Query: 444  RGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYS 503
                PR  F S    +     +G++ +    +  C      ++++V+D L  I +  +Y 
Sbjct: 528  ESP-PRFYFSSNGTSD---VITGSIQVS-SREANCRTHQAFMRKDVRDILTPIQIEAAYH 582

Query: 504  LQTPRLRRQAPGQGLPPVAPIL-NAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFC 562
            L  P +  +   +  PP+ PIL    +    +  I+F +    E+  C ++LQ+      
Sbjct: 583  L-GPHVISKRSTEEFPPLQPILQQKKEKDIMKKTINFARFCAHEN--CSADLQVSAKIGF 639

Query: 563  TRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLV 622
             +  + +               A+     + L + + N           GDDA+E  L V
Sbjct: 640  LKPHENK------------TYLAVGSMKTLMLNVSLFNA----------GDDAYETTLHV 677

Query: 623  MLPDSLHYSGVRALDPAEKPL---CLSNENASHVECELGN-PMKRGAQVTFYLILSTSGI 678
             LP  L++  ++ L+  EK +      N     ++C +G   +   +++    +L  S +
Sbjct: 678  KLPVGLYF--IKILELEEKQINCEVTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSL 735

Query: 679  SIETTELEVELLLATISEQELHPVSARARVFIELP------LSIAGMAIPQQLFFSGVVR 732
            S    +L + +     +E+E+  +   +RV + +P      L++ G   P    +     
Sbjct: 736  SRAEEDLSITVHATCENEEEMDNLK-HSRVTVAIPLKYEVKLTVHGFVNPTSFVYGSNDE 794

Query: 733  GERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEG 792
             E     E  +  K+     V N G S+    +  + IM P+  +     L+        
Sbjct: 795  NE----PETCMVEKMNLTFHVINTGNSMAP--NVSVEIMVPNSFSPQTDKLF-------- 840

Query: 793  GQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWP--VSSAEKK 850
                          NIL +   + +      E  ++    E+Q+ +M      V    K 
Sbjct: 841  --------------NILDVQTTTGE---CHFENYQRVCALEQQKSAMQTLKGIVRFLSKT 883

Query: 851  KNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANIT 910
                L C +   +C+ F C     +      V  +L     + E     +L+  +RA   
Sbjct: 884  DKRLLYCIKADPHCLNFLCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGF 943

Query: 911  VKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMG 970
             + + + + L     V  V++               +I  ++L GL+VL L+  ++WK G
Sbjct: 944  PEPNPRVIELNKDENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAG 1003

Query: 971  FFKR 974
            FFKR
Sbjct: 1004 FFKR 1007


>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
          Length = 1167

 Score =  184 bits (467), Expect = 4e-46
 Identities = 229/886 (25%), Positives = 375/886 (42%), Gaps = 135/886 (15%)

Query: 115  LLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGFSI 174
            +LFG  G Y+W G+    L  +G   L      P     E E  P L    A  Y G+S+
Sbjct: 386  ILFGMVGAYDWGGSV---LWLEGGHRLF-----PPRMALEDEFPPALQNHAA--YLGYSV 435

Query: 175  DSGKGLVRAEELSFVAGAPRANHKGAVVI--LRKDSASRLVPEVMLSGERLTSGFGYSLA 232
             S   L+R     F++GAPR  H+G V+   L+KD A R+     L GE++ S FG  L 
Sbjct: 436  SSM--LLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQS--LQGEQIGSYFGSELC 491

Query: 233  VADLNSDGWPD-LIVGAPYFFERQEELGGAVYVYL-NQGGHWAGISPLRLCGSPDSMFGI 290
              D + DG  D L+V AP F   Q +  G VYVYL  Q         L+     D+ FG 
Sbjct: 492  PLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQPEPPQDARFGF 551

Query: 291  SLAVLGDLNQDGFPDIAVGAPFDG--DGKVFIYHGSSLGVVAKPSQVLEGEAV--GIKSF 346
            ++  L DLNQDGF D+AVGAP +    G +++YHG+  GV   P+Q +   ++   +  F
Sbjct: 552  AMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAASMPHALSYF 611

Query: 347  GYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNC--AG 404
            G S+ G LD+DG+   D+ VG+    A+L  +RPI+H++  + + P++I + Q +C   G
Sbjct: 612  GRSVDGRLDLDGDDLVDVAVGA-QGAAILLSSRPIVHLTPSLEVTPQAISVVQRDCRRRG 670

Query: 405  GHSVCVDLRVCFSYIA-VPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQ 463
              +VC+   +CF   +  P  +     + +   A  D    G         + L   + +
Sbjct: 671  QEAVCLTAALCFQVTSRTPGRWDHQFYMRFT--ASLDEWTAGARAAFDGSGQRLSPRRLR 728

Query: 464  AS-GTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVA 522
             S G V  +  H  V          +  D LR + +T++++L         PG       
Sbjct: 729  LSVGNVTCEQLHFHVL---------DTSDYLRPVALTVTFALD----NTTKPG------- 768

Query: 523  PILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGT-T 581
            P+LN   P++ +  + F K  CG D  C ++L L                + MD+ G+  
Sbjct: 769  PVLNEGSPTSIQKLVPFSKD-CGPDNECVTDLVL---------------QVNMDIRGSRK 812

Query: 582  ALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEK 641
            A F + G    G   ++ +   +  +     ++A+   L ++   +LH + +     +  
Sbjct: 813  APFVVRG----GRRKVLVSTTLENRK-----ENAYNTSLSLIFSRNLHLASLTPQRESPI 863

Query: 642  PLCLSNENASHVECELGNPM-KRGAQVTFYLILSTSGISIETTELEVELLLATISEQE-- 698
             +  +  +A    C +G+P+ + GA+VTF L    S  S+  +++ V+L  ++ S +   
Sbjct: 864  KVECAAPSAHARLCSVGHPVFQTGAKVTFLLEFEFSCSSL-LSQVFVKLTASSDSLERNG 922

Query: 699  -LHPVSARARVFIELPLSIAGMAIPQQLFF--SGVVRGERAMQSERDVGSKVKYEVTVSN 755
             L   +A+   +I+          P  LF   S + R E        VG   +++ T+  
Sbjct: 923  TLQDNTAQTSAYIQYE--------PHLLFSSESTLHRYEVHPYGTLPVGPGPEFKTTLRV 974

Query: 756  QGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDS 815
            Q      +    ++ + P     G + L   QV         Q     P P +       
Sbjct: 975  QNLGCYVVSGLIISALLPAVAHGGNYFLSLSQVITNNASCIVQNLTEPPGPPV------- 1027

Query: 816  RDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFD 875
                      PE+ +   R   S                         C V  C L    
Sbjct: 1028 ---------HPEELQHTNRLNGS----------------------NTQCQVVRCHLGQLA 1056

Query: 876  RAAVLHV-WGRLWNSTFLEEYSAVKSLEVIVRANI-TVKSSIKNLMLRDASTVIPVMVYL 933
            +   + V   RL ++ F    +  KSL V+    + T + S+  L L +AS     ++ +
Sbjct: 1057 KGTEVSVGLLRLVHNEFFRR-AKFKSLTVVSTFELGTEEGSV--LQLTEASRWSESLLEV 1113

Query: 934  DPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPE 979
                 +   +  W+++ +VL GLL+LALLV  LWK+GFF   K PE
Sbjct: 1114 VQTRPIL--ISLWILIGSVLGGLLLLALLVFCLWKLGFFAHKKIPE 1157


>gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]
          Length = 1170

 Score =  159 bits (402), Expect = 1e-38
 Identities = 234/920 (25%), Positives = 379/920 (41%), Gaps = 175/920 (19%)

Query: 114  YLLFGAPGTYNWKGTARVELCAQGSADL-AHLDDGPYEAGGEKEQDPRLIPVPANSYFGF 172
            + + GA G  +W G         G  DL A L D  +  G E      L P     Y G+
Sbjct: 362  HAVVGAVGAKDWAG---------GFLDLKADLQDDTF-IGNEP-----LTPEVRAGYLGY 406

Query: 173  SIDSGKGLVRAEELSFVA-GAPRANHKGAVVILRKDSASRLVPEVM-LSGERLTSGFGYS 230
            ++     L   ++ S +A GAPR  H G V++ ++        +V  + G ++ S FG  
Sbjct: 407  TVT---WLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGE 463

Query: 231  LAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLC-GSPDSMF 288
            L   D++ DG  +L+ +GAP F+  Q   GG V++Y  +   +  +S L+   G P   F
Sbjct: 464  LCGVDVDQDGETELLLIGAPLFYGEQR--GGRVFIYQRRQLGFEEVSELQGDPGYPLGRF 521

Query: 289  GISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV--GIKSF 346
            G ++  L D+N DG  D+AVGAP +  G V+I++G   G+  +PSQ +EG  V  GI+ F
Sbjct: 522  GEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWF 581

Query: 347  GYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGH 406
            G S+ G  D++G+   D+ VG+ +   VL  +RP++ +   +S +P  I + +  C+   
Sbjct: 582  GRSIHGVKDLEGDGLADVAVGAESQMIVL-SSRPVVDMVTLMSFSPAEIPVHEVECSYST 640

Query: 407  S----VCVDLRVCFSYIA-VPSSYSPTVA-LDYVLDADTDR-RLRGQVPRVTF-LSRNLE 458
            S      V++ +CF   + +P      VA L Y L  D  R R RG  P     L RN+ 
Sbjct: 641  SNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIA 700

Query: 459  EPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQ----TPRLRRQAP 514
                 +             C D  F     V+D +  I V+L++SL     TPR +R A 
Sbjct: 701  VTTSMS-------------CTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQR-AQ 746

Query: 515  GQGLPPVAPILNAHQPS--TQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQP 572
            G+ +PP+       +PS  ++  EI F K  CGEDK C++NL++             F P
Sbjct: 747  GKDIPPIL------RPSLHSETWEIPFEKN-CGEDKKCEANLRV------------SFSP 787

Query: 573  LPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSG 632
                    TA  +LS      +EL ++NL           +DA+  QL +  P  L +  
Sbjct: 788  ARSRALRLTAFASLS------VELSLSNLE----------EDAYWVQLDLHFPPGLSFRK 831

Query: 633  VRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLA 692
            V  L                         K  +Q+          +S E    E  LL  
Sbjct: 832  VEML-------------------------KPHSQIP---------VSCEELPEESRLLSR 857

Query: 693  TISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVT 752
             +S              +  P+  AG ++  Q+ F+ +V        E      +   VT
Sbjct: 858  ALSCN------------VSSPIFKAGHSVALQMMFNTLVNSSWGDSVE------LHANVT 899

Query: 753  VSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILH-- 810
             +N+   L    SA   I           +LYP+ + ++  +        +P+   +H  
Sbjct: 900  CNNEDSDLLEDNSATTIIP----------ILYPINILIQDQEDSTLYVSFTPKGPKIHQV 949

Query: 811  -------LDVDSRDRRRRELEP------PEQQEPGERQEPSMSWWPVSSAEKKKNITLDC 857
                   +     D     LE       P  + P   Q       PV    +      D 
Sbjct: 950  KHMYQVRIQPSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDA 1009

Query: 858  ARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKN 917
            A       +F CP+  F +  ++ V G L     + E  A     +    +I+  SS   
Sbjct: 1010 AEPCLPGALFRCPVV-FRQEILVQVIGTL---ELVGEIEASSMFSLCSSLSISFNSSKHF 1065

Query: 918  LMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKH 977
             +    +++  V++ +D   VV E    ++ +L+ + GLL+L L+ ++L+K+GFFKR   
Sbjct: 1066 HLYGSNASLAQVVMKVD---VVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLK 1122

Query: 978  PEATVPQYHAVKIPREDRQQ 997
             +    +     IP ED +Q
Sbjct: 1123 EKMEAGRGVPNGIPAEDSEQ 1142


>gi|52485853 integrin, alpha 11 precursor [Homo sapiens]
          Length = 1188

 Score =  158 bits (399), Expect = 3e-38
 Identities = 167/659 (25%), Positives = 287/659 (43%), Gaps = 81/659 (12%)

Query: 67  FVLSQDLAIRDELDG-GEWKFC-EGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYN 124
           F ++ + A++D +D  G+  F  EG  +    FG     T  +       +L GA G Y+
Sbjct: 330 FNVTDEAALKDIVDALGDRIFSLEGTNKNETSFGLEMSQTGFSSHVVEDGVLLGAVGAYD 389

Query: 125 WKGTARVELCAQGSADL--AHLDDGPYEAGGEKEQDPRLIPVPANSYFGFSIDSGKGLVR 182
           W G    E  A     L  ++L + P E                 +Y G+++ S   +  
Sbjct: 390 WNGAVLKETSAGKVIPLRESYLKEFPEELKNH------------GAYLGYTVTSV--VSS 435

Query: 183 AEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWP 242
            +   +VAGAPR NH G V++    +   L     + G+++ S FG  +   D++ DG  
Sbjct: 436 RQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYFGSEITSVDIDGDGVT 495

Query: 243 D-LIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGS-PDSMFGISLAVLGDLNQ 300
           D L+VGAP +F    E  G VYVY  +   +     L+   S  ++ FG S+A + DLNQ
Sbjct: 496 DVLLVGAPMYFNEGRE-RGKVYVYELRQNLFVYNGTLKDSHSYQNARFGSSIASVRDLNQ 554

Query: 301 DGFPDIAVGAPFDGD--GKVFIYHGSSLGVVAKPSQVLEGE--AVGIKSFGYSLSGSLDM 356
           D + D+ VGAP + +  G ++I+HG    ++  P Q +     A G++ FG S+ G LD+
Sbjct: 555 DSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRITASELATGLQYFGCSIHGQLDL 614

Query: 357 DGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNC--AGGHSVCVDLRV 414
           + +   DL VG+L +  +L+ +RP++ ++  +   P  I++   +C  +G  + C+   +
Sbjct: 615 NEDGLIDLAVGALGNAVILW-SRPVVQINASLHFEPSKINIFHRDCKRSGRDATCLAAFL 673

Query: 415 CFSYI-AVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQ 473
           CF+ I   P   + TV + Y    D     R   PR      +L+E   + +    L   
Sbjct: 674 CFTPIFLAPHFQTTTVGIRYNATMDE----RRYTPRA-----HLDEGGDRFTNRAVLLSS 724

Query: 474 HDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQ 533
              +C    F + +   D ++ +  ++ YSL+             P   P+L+   P+T 
Sbjct: 725 GQELCERINFHVLDTA-DYVKPVTFSVEYSLED------------PDHGPMLDDGWPTTL 771

Query: 534 RAEIHFLKQGCGEDKICQSNLQL-------VRARFCTRV-----SDTEFQPLPMDVDGTT 581
           R  + F   GC ED+ C  +L L           +C RV      D     L  D   TT
Sbjct: 772 RVSVPFW-NGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFD---TT 827

Query: 582 ALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEK 641
                S +  + +E  + N           G++A+   L +    +L ++ +   + ++ 
Sbjct: 828 VFIIESTRQRVAVEATLEN----------RGENAYSTVLNISQSANLQFASLIQKEDSDG 877

Query: 642 PL-CLSNENASHVE-CELGNPMKRG-AQVTFYLILSTSGISIETTELEVELLLATISEQ 697
            + C++ E     + C +  P  R  A+V F L    S  SI    LE+EL   + S +
Sbjct: 878 SIECVNEERRLQKQVCNVSYPFFRAKAKVAFRLDFEFSK-SIFLHHLEIELAAGSDSNE 935



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 21/34 (61%), Positives = 28/34 (82%)

Query: 943  VPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK 976
            VP W+I+ + L GLL+LALLVL LWK+GFF+ A+
Sbjct: 1140 VPIWIIVGSTLGGLLLLALLVLALWKLGFFRSAR 1173


>gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]
          Length = 1086

 Score =  157 bits (397), Expect = 5e-38
 Identities = 233/920 (25%), Positives = 378/920 (41%), Gaps = 176/920 (19%)

Query: 114  YLLFGAPGTYNWKGTARVELCAQGSADL-AHLDDGPYEAGGEKEQDPRLIPVPANSYFGF 172
            + + GA G  +W G         G  DL A L D  +  G E      L P     Y G+
Sbjct: 279  HAVVGAVGAKDWAG---------GFLDLKADLQDDTF-IGNEP-----LTPEVRAGYLGY 323

Query: 173  SIDSGKGLVRAEELSFVA-GAPRANHKGAVVILRKDSASRLVPEVM-LSGERLTSGFGYS 230
            ++     L   ++ S +A GAPR  H G V++ ++        +V  + G ++ S FG  
Sbjct: 324  TVT---WLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGE 380

Query: 231  LAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLC-GSPDSMF 288
            L   D++ DG  +L+ +GAP F+  Q   GG V++Y  +   +  +S L+   G P   F
Sbjct: 381  LCGVDVDQDGETELLLIGAPLFYGEQR--GGRVFIYQRRQLGFEEVSELQGDPGYPLGRF 438

Query: 289  GISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV--GIKSF 346
            G ++  L D+N DG  D+AVGAP +  G V+I++G   G+  +PSQ +EG  V  GI+ F
Sbjct: 439  GEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWF 498

Query: 347  GYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGH 406
            G S+ G  D++G+   D+ VG+ +   VL  +RP++ +   +S +P  I + +  C+   
Sbjct: 499  GRSIHGVKDLEGDGLADVAVGAESQMIVL-SSRPVVDMVTLMSFSPAEIPVHEVECSYST 557

Query: 407  S----VCVDLRVCFSYIA-VPSSYSPTVA-LDYVLDADTDR-RLRGQVPRVTF-LSRNLE 458
            S      V++ +CF   + +P      VA L Y L  D  R R RG  P     L RN+ 
Sbjct: 558  SNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIA 617

Query: 459  EPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQ----TPRLRRQAP 514
                 +             C D  F     V+D +  I V+L++SL     TPR +R   
Sbjct: 618  VTTSMS-------------CTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRA-- 662

Query: 515  GQGLPPVAPILNAHQPS--TQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQP 572
            G+ +PP+       +PS  ++  EI F K  CGEDK C++NL++             F P
Sbjct: 663  GKDIPPIL------RPSLHSETWEIPFEKN-CGEDKKCEANLRV------------SFSP 703

Query: 573  LPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSG 632
                    TA  +LS      +EL ++NL           +DA+  QL +  P  L +  
Sbjct: 704  ARSRALRLTAFASLS------VELSLSNLE----------EDAYWVQLDLHFPPGLSFRK 747

Query: 633  VRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLA 692
            V  L                         K  +Q+          +S E    E  LL  
Sbjct: 748  VEML-------------------------KPHSQIP---------VSCEELPEESRLLSR 773

Query: 693  TISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVT 752
             +S              +  P+  AG ++  Q+ F+ +V        E      +   VT
Sbjct: 774  ALSCN------------VSSPIFKAGHSVALQMMFNTLVNSSWGDSVE------LHANVT 815

Query: 753  VSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILH-- 810
             +N+   L    SA   I           +LYP+ + ++  +        +P+   +H  
Sbjct: 816  CNNEDSDLLEDNSATTIIP----------ILYPINILIQDQEDSTLYVSFTPKGPKIHQV 865

Query: 811  -------LDVDSRDRRRRELEP------PEQQEPGERQEPSMSWWPVSSAEKKKNITLDC 857
                   +     D     LE       P  + P   Q       PV    +      D 
Sbjct: 866  KHMYQVRIQPSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDA 925

Query: 858  ARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKN 917
            A       +F CP+  F +  ++ V G L     + E  A     +    +I+  SS   
Sbjct: 926  AEPCLPGALFRCPVV-FRQEILVQVIGTL---ELVGEIEASSMFSLCSSLSISFNSSKHF 981

Query: 918  LMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKH 977
             +    +++  V++ +D   VV E    ++ +L+ + GLL+L L+ ++L+K+GFFKR   
Sbjct: 982  HLYGSNASLAQVVMKVD---VVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLK 1038

Query: 978  PEATVPQYHAVKIPREDRQQ 997
             +    +     IP ED +Q
Sbjct: 1039 EKMEAGRGVPNGIPAEDSEQ 1058


>gi|34452173 integrin alpha X precursor [Homo sapiens]
          Length = 1163

 Score =  146 bits (368), Expect = 1e-34
 Identities = 242/915 (26%), Positives = 366/915 (40%), Gaps = 173/915 (18%)

Query: 101  QQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQ-DP 159
            Q+G +A F+PD   L  GA G++ W G           A L   +  P      +E  D 
Sbjct: 353  QEGFSAVFTPDGPVL--GAVGSFTWSG----------GAFLYPPNMSPTFINMSQENVDM 400

Query: 160  RLIPVPANSYFGFSIDSG--KGLVRAEELSFVAGAPRANHKGAVVILRKDSAS-RLVPEV 216
            R      +SY G+S +    KG+      S V GAPR  H G  VI  + S   R+  EV
Sbjct: 401  R------DSYLGYSTELALWKGVQ-----SLVLGAPRYQHTGKAVIFTQVSRQWRMKAEV 449

Query: 217  MLSGERLTSGFGYSLAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVY-LNQGGH--W 272
              +G ++ S FG SL   D++SDG  DL+ +GAP+++E+    GG V V  L +G    W
Sbjct: 450  --TGTQIGSYFGASLCSVDVDSDGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGWRRWW 505

Query: 273  AGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSSLGVVA 330
                     G P   FG +L VLGD+N D   D+ +GAP + +  G V+++HG  LG   
Sbjct: 506  CDAVLYGEQGHPWGRFGAALTVLGDVNGDKLTDVVIGAPGEEENRGAVYLFHG-VLGPSI 564

Query: 331  KP--SQVLEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSH 386
             P  SQ + G  +   ++ FG +LSG  D+  +   DL VG+     +L R RP+L V  
Sbjct: 565  SPSHSQRIAGSQLSSRLQYFGQALSGGQDLTQDGLVDLAVGARGQ-VLLLRTRPVLWVGV 623

Query: 387  EVSIAPRSIDLEQPNC---AGGHSVCVDLRVCFSYIAVPS-------SYSPTVALDYVLD 436
             +   P  I      C          V   +C  YI   S           +V LD  LD
Sbjct: 624  SMQFIPAEIPRSAFECREQVVSEQTLVQSNICL-YIDKRSKNLLGSRDLQSSVTLDLALD 682

Query: 437  ADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAI 496
                 RL    PR TF     +E K+++   V +       C +    L   V+D +  I
Sbjct: 683  PG---RLS---PRATF-----QETKNRSLSRVRVLGLKAH-CENFNLLLPSCVEDSVTPI 730

Query: 497  VVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQL 556
             + L+++L         P      + P+L A       A + F ++ CG D ICQ NL  
Sbjct: 731  TLRLNFTLV------GKPLLAFRNLRPMLAADAQRYFTASLPF-EKNCGADHICQDNL-- 781

Query: 557  VRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAH 616
                            +     G  +L   S    +  E+MV N          DG+D++
Sbjct: 782  ---------------GISFSFPGLKSLLVGSNLE-LNAEVMVWN----------DGEDSY 815

Query: 617  EAQLLVMLPDSLHYSGV---------RALDPAEKPLCLSNENASHVECELGNPMKR-GAQ 666
               +    P  L Y  V         R+L        + ++      C + + + R GAQ
Sbjct: 816  GTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFRGGAQ 875

Query: 667  VTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLF 726
            +TF   L+T  +S +    +  LL A +S +   P +++    +ELP+  A   +     
Sbjct: 876  ITF---LATFDVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQLELPVKYAVYTVVSS-- 930

Query: 727  FSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEI-ANGKWLLYP 785
                 +     +SE        +   V+N GQ  R L    +N   P E+     W    
Sbjct: 931  HEQFTKYLNFSESEEKESHVAMHRYQVNNLGQ--RDL-PVSINFWVPVELNQEAVW---- 983

Query: 786  MQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVS 845
            M VE+   Q P  +  CS                  ++ PP                   
Sbjct: 984  MDVEVSHPQNPSLR--CS----------------SEKIAPPASD---------------F 1010

Query: 846  SAEKKKNITLDCARGTANCVVFSC--PLYSFDRAAVLHVWGRL---WNSTFLEEYSAVKS 900
             A  +KN  LDC+   A C+ F C  P +S        + G L   W    L+     K 
Sbjct: 1011 LAHIQKNPVLDCS--IAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQ-----KK 1063

Query: 901  LEVIVRANITVKSSI-KNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVL 959
            + V+  A IT  +S+   L  ++A         L+   V     P  +I+ + + GLL+L
Sbjct: 1064 VSVVSVAEITFDTSVYSQLPGQEAFMRAQTTTVLEKYKV---HNPTPLIVGSSIGGLLLL 1120

Query: 960  ALLVLLLWKMGFFKR 974
            AL+  +L+K+GFFKR
Sbjct: 1121 ALITAVLYKVGFFKR 1135


>gi|116295258 integrin alpha 2 precursor [Homo sapiens]
          Length = 1181

 Score =  145 bits (367), Expect = 1e-34
 Identities = 159/626 (25%), Positives = 270/626 (43%), Gaps = 88/626 (14%)

Query: 88  EGRPQGHEQFGF--CQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLD 145
           EG  QG + F     Q G +A +S  +  L+ GA G + W GT  V+  + G        
Sbjct: 365 EGTVQGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTI-VQKTSHGHLIF---- 419

Query: 146 DGPYEAGGEKEQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILR 205
             P +A  +  QD        +SY G+S+ +   +   E   FVAGAPRAN+ G +V+  
Sbjct: 420 --PKQAFDQILQDRN-----HSSYLGYSVAA---ISTGESTHFVAGAPRANYTGQIVLYS 469

Query: 206 KDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPD-LIVGAPYFFERQEELGGAVYV 264
            +    +       G+++ S FG  L   D++ D   D L+VGAP +    ++  G VY+
Sbjct: 470 VNENGNITVIQAHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYL 529

Query: 265 YLNQGG----HWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFD--GDGKV 318
           +  + G    H     P    G  ++ FG ++A L D+N DGF D+ VG+P +    G V
Sbjct: 530 FTIKEGILGQHQFLEGPE---GIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAV 586

Query: 319 FIYHGSSLGVVAKPSQVLEGEAVGIKS----FGYSLSGSLDMDGNQYPDLLVGSLADTAV 374
           +IY+G    +  K SQ + G     +S    FG SL G  D++G+   D+ +G+      
Sbjct: 587 YIYNGHQGTIRTKYSQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQ 646

Query: 375 LFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYV 434
           L+ ++ I  V+ E S  P  I L   N        + L++CFS    P+  +  VA+ Y 
Sbjct: 647 LW-SQSIADVAIEASFTPEKITLVNKNAQ------IILKLCFSAKFRPTKQNNQVAIVYN 699

Query: 435 LDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLR 494
           +  D D    G   RVT  SR L +  ++      +     + C + +  +QE   D + 
Sbjct: 700 ITLDAD----GFSSRVT--SRGLFKENNERCLQKNMVVNQAQSCPEHIIYIQE-PSDVVN 752

Query: 495 AIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNL 554
           ++ + +  SL+             P  +P L A+  + +   I F K  CGED +C S+L
Sbjct: 753 SLDLRVDISLEN------------PGTSPALEAYSETAKVFSIPFHKD-CGEDGLCISDL 799

Query: 555 QL-VRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGD 613
            L VR     ++   + QP  +        F+++                     +   +
Sbjct: 800 VLDVR-----QIPAAQEQPFIVSNQNKRLTFSVT--------------------LKNKRE 834

Query: 614 DAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNP-MKRGAQVTFYLI 672
            A+   ++V   ++L ++         +  C    +   V C++G P +KR  QVTF + 
Sbjct: 835 SAYNTGIVVDFSENLFFASFSLPVDGTEVTCQVAASQKSVACDVGYPALKREQQVTFTI- 893

Query: 673 LSTSGISIETTELEVELLLATISEQE 698
                 +++  + +  L    +SE +
Sbjct: 894 --NFDFNLQNLQNQASLSFQALSESQ 917



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 38/117 (32%), Positives = 63/117 (53%), Gaps = 10/117 (8%)

Query: 861  TANCVVFSCPLYSFDRAA--VLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNL 918
            TA+C   +C L          ++V  R+WN TF    S  +++++   A I   +  +  
Sbjct: 1052 TASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFAS--STFQTVQLTAAAEINTYNP-EIY 1108

Query: 919  MLRDASTVIPVMVYL-DPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKR 974
            ++ D +  IP+M+   D  A V  GV    I+ +++AG+L+L  LV +LWK+GFFKR
Sbjct: 1109 VIEDNTVTIPLMIMKPDEKAEVPTGV----IIGSIIAGILLLLALVAILWKLGFFKR 1161


>gi|148728188 integrin, alpha E precursor [Homo sapiens]
          Length = 1179

 Score =  145 bits (365), Expect = 3e-34
 Identities = 137/475 (28%), Positives = 215/475 (45%), Gaps = 80/475 (16%)

Query: 111 DSHYLLFGAPGTYNWKGTA--------RVELCAQGSADLAHLDDGPYEAGGEKEQDPRLI 162
           D   +L GA G ++W G A        R     Q +A  A  +   Y             
Sbjct: 412 DERQVLLGAVGAFDWSGGALLYDTRSRRGRFLNQTAAAAADAEAAQY------------- 458

Query: 163 PVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGER 222
                SY G+++     L +   LS++AGAPR  H GAV  L+K+        V L GE+
Sbjct: 459 -----SYLGYAVAV---LHKTCSLSYIAGAPRYKHHGAVFELQKEGREASFLPV-LEGEQ 509

Query: 223 LTSGFGYSLAVADLNSDGWPD-LIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLC 281
           + S FG  L   D++ DG  D L+V AP++    EE  G VYVY       +      L 
Sbjct: 510 MGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEE--GRVYVYRLSEQDGSFSLARILS 567

Query: 282 GSP---DSMFGISLAVLGDLNQDGFPDIAVGAPFDG--------DGKVFIYHGSSLGVVA 330
           G P   ++ FG ++A +GDL+QD   D+A+GAP +G         G V+IY+G   G+ A
Sbjct: 568 GHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSA 627

Query: 331 KPSQVLEGEAV--GIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEV 388
            PSQ +    V  G++ FG S++G  D+ G+   D+ VG+L   AV+FR+RP++ +   +
Sbjct: 628 SPSQRIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLGQ-AVVFRSRPVVRLKVSM 686

Query: 389 SIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSP---TVALDYVLDADTDR-RLR 444
           +  P ++ +       G +  V++R+CF   +V ++         L++ LD D  + R R
Sbjct: 687 AFTPSALPI-------GFNGVVNVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRR 739

Query: 445 GQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQEN---VKDKLRAIVVTLS 501
            Q   V      L E    +SG+        ++C D +    E     +D      V +S
Sbjct: 740 LQCSDVRSCLGCLRE---WSSGS--------QLCEDLLLMPTEGELCEEDCFSNASVKVS 788

Query: 502 YSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQL 556
           Y LQTP  +   P        PIL+ +       ++ + ++ C     C + LQL
Sbjct: 789 YQLQTPEGQTDHP-------QPILDRYTEPFAIFQLPY-EKACKNKLFCVAELQL 835



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 13/28 (46%), Positives = 22/28 (78%)

Query: 947  VILLAVLAGLLVLALLVLLLWKMGFFKR 974
            +I+   + GLLVL +++++L+K GFFKR
Sbjct: 1127 IIIKGSVGGLLVLIVILVILFKCGFFKR 1154


>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
          Length = 1153

 Score =  132 bits (331), Expect = 2e-30
 Identities = 203/908 (22%), Positives = 354/908 (38%), Gaps = 157/908 (17%)

Query: 101  QQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSA--DLAHLDDGPYEAGGEKEQD 158
            Q+G +AA +  S+  L    G+Y+W G   +    + S   ++  +D    +A       
Sbjct: 352  QEGFSAAIT--SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDA------- 402

Query: 159  PRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVML 218
                      Y G++      ++R    S V GAPR  H G V + R+++         +
Sbjct: 403  ----------YLGYAAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGM-WESNANV 448

Query: 219  SGERLTSGFGYSLAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVY---LNQGGHWAG 274
             G ++ + FG SL   D++S+G  DL+ +GAP+++E+    GG V V      Q   W  
Sbjct: 449  KGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGQRARWQC 506

Query: 275  ISPLR-LCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSS-LGVVA 330
             + L    G P   FG +L VLGD+N D   D+A+GAP + D  G V+++HG+S  G+  
Sbjct: 507  DAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISP 566

Query: 331  KPSQVLEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEV 388
              SQ + G  +   ++ FG SLSG  D+  +   DL VG+     +L R++P+L V   +
Sbjct: 567  SHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGH-VLLLRSQPVLRVKAIM 625

Query: 389  SIAPRSIDLEQPNC---------AGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADT 439
               PR +      C         AG   VC+ ++               V  D  LD+  
Sbjct: 626  EFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSG- 684

Query: 440  DRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVT 499
                R     V   ++N    + Q  G         + C     QL   ++D +  IV+ 
Sbjct: 685  ----RPHSRAVFNETKNSTRRQTQVLGLT-------QTCETLKLQLPNCIEDPVSPIVLR 733

Query: 500  LSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRA 559
            L++SL         P      + P+L A         +   ++ CG D ICQ +L +   
Sbjct: 734  LNFSLV------GTPLSAFGNLRPVL-AEDAQRLFTALFPFEKNCGNDNICQDDLSIT-- 784

Query: 560  RFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQ 619
                      F  + +D         + G     + + V N          DG+D++  Q
Sbjct: 785  ----------FSFMSLD------CLVVGGPREFNVTVTVRN----------DGEDSYRTQ 818

Query: 620  LLVMLPDSLHYSGVRAL--DPAEKPLCLSNENASHVE---------CELGNPM-KRGAQV 667
            +    P  L Y  V  L    +++   L+ E+AS  E         C + +P+    ++V
Sbjct: 819  VTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEV 878

Query: 668  TFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFF 727
            TF +       +    +L   LL A ++ +   P + +    +ELP+     A+   +  
Sbjct: 879  TFNITFDVDSKASLGNKL---LLKANVTSENNMPRTNKTEFQLELPVK---YAVYMVVTS 932

Query: 728  SGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQ 787
             GV        +  +    ++++  VSN GQ    +   F               L P++
Sbjct: 933  HGVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPISLVF---------------LVPVR 977

Query: 788  VELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSA 847
            +          + +   RP +   +  S     +E  P                     A
Sbjct: 978  L---------NQTVIWDRPQVTFSENLSSTCHTKERLPSHSD---------------FLA 1013

Query: 848  EKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRA 907
            E +K   ++C+      +    P +         + G L    +++  ++   L ++  A
Sbjct: 1014 ELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIK--TSHNHLLIVSTA 1071

Query: 908  NITVKSSIKNLMLRDASTV-IPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLL 966
             I    S+  L+    + V       ++P  V     P  +I+ + + GLL+LAL+   L
Sbjct: 1072 EILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPN---PLPLIVGSSVGGLLLLALITAAL 1128

Query: 967  WKMGFFKR 974
            +K+GFFKR
Sbjct: 1129 YKLGFFKR 1136


>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
          Length = 1152

 Score =  131 bits (329), Expect = 4e-30
 Identities = 204/907 (22%), Positives = 356/907 (39%), Gaps = 156/907 (17%)

Query: 101  QQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSA--DLAHLDDGPYEAGGEKEQD 158
            Q+G +AA +  S+  L    G+Y+W G   +    + S   ++  +D    +A       
Sbjct: 352  QEGFSAAIT--SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDA------- 402

Query: 159  PRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVML 218
                      Y G++      ++R    S V GAPR  H G V + R+++         +
Sbjct: 403  ----------YLGYAAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGM-WESNANV 448

Query: 219  SGERLTSGFGYSLAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVY-LNQG-GHWAGI 275
             G ++ + FG SL   D++S+G  DL+ +GAP+++E+    GG V V  L +G   W   
Sbjct: 449  KGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGRARWQCD 506

Query: 276  SPLR-LCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSS-LGVVAK 331
            + L    G P   FG +L VLGD+N D   D+A+GAP + D  G V+++HG+S  G+   
Sbjct: 507  AVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPS 566

Query: 332  PSQVLEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVS 389
             SQ + G  +   ++ FG SLSG  D+  +   DL VG+     +L R++P+L V   + 
Sbjct: 567  HSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGH-VLLLRSQPVLRVKAIME 625

Query: 390  IAPRSIDLEQPNC---------AGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTD 440
              PR +      C         AG   VC+ ++               V  D  LD+   
Sbjct: 626  FNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSG-- 683

Query: 441  RRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTL 500
               R     V   ++N    + Q  G         + C     QL   ++D +  IV+ L
Sbjct: 684  ---RPHSRAVFNETKNSTRRQTQVLGLT-------QTCETLKLQLPNCIEDPVSPIVLRL 733

Query: 501  SYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRAR 560
            ++SL         P      + P+L A         +   ++ CG D ICQ +L +    
Sbjct: 734  NFSLV------GTPLSAFGNLRPVL-AEDAQRLFTALFPFEKNCGNDNICQDDLSIT--- 783

Query: 561  FCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQL 620
                     F  + +D         + G     + + V N          DG+D++  Q+
Sbjct: 784  ---------FSFMSLD------CLVVGGPREFNVTVTVRN----------DGEDSYRTQV 818

Query: 621  LVMLPDSLHYSGVRAL--DPAEKPLCLSNENASHVE---------CELGNPM-KRGAQVT 668
                P  L Y  V  L    +++   L+ E+AS  E         C + +P+    ++VT
Sbjct: 819  TFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVT 878

Query: 669  FYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFS 728
            F +       +    +L   LL A ++ +   P + +    +ELP+     A+   +   
Sbjct: 879  FNITFDVDSKASLGNKL---LLKANVTSENNMPRTNKTEFQLELPVK---YAVYMVVTSH 932

Query: 729  GVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQV 788
            GV        +  +    ++++  VSN GQ    +   F               L P+++
Sbjct: 933  GVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPISLVF---------------LVPVRL 977

Query: 789  ELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAE 848
                      + +   RP +   +  S     +E  P                     AE
Sbjct: 978  ---------NQTVIWDRPQVTFSENLSSTCHTKERLPSHSD---------------FLAE 1013

Query: 849  KKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRAN 908
             +K   ++C+      +    P +         + G L    +++  ++   L ++  A 
Sbjct: 1014 LRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIK--TSHNHLLIVSTAE 1071

Query: 909  ITVKSSIKNLMLRDASTV-IPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLW 967
            I    S+  L+    + V       ++P  V     P  +I+ + + GLL+LAL+   L+
Sbjct: 1072 ILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPN---PLPLIVGSSVGGLLLLALITAALY 1128

Query: 968  KMGFFKR 974
            K+GFFKR
Sbjct: 1129 KLGFFKR 1135


>gi|62548866 integrin, alpha D precursor [Homo sapiens]
          Length = 1161

 Score =  124 bits (310), Expect = 6e-28
 Identities = 223/933 (23%), Positives = 376/933 (40%), Gaps = 187/933 (20%)

Query: 88   EGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDG 147
            + R     Q    Q+G + A + D  +L  GA G+++W G           A L   +  
Sbjct: 339  QSRASSSFQHEMSQEGFSTALTMDGLFL--GAVGSFSWSG----------GAFLYPPNMS 386

Query: 148  PYEAGGEKEQ-DPRLIPVPANSYFGFSIDSG--KGLVRAEELSFVAGAPRANHKGAVVIL 204
            P      +E  D R      +SY G+S +    KG+      + V GAPR  H G  VI 
Sbjct: 387  PTFINMSQENVDMR------DSYLGYSTELALWKGVQ-----NLVLGAPRYQHTGKAVIF 435

Query: 205  RKDSAS-RLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLI-VGAPYFFERQEELGGAV 262
             + S   R   EV  +G ++ S FG SL   D++SDG  DLI +GAP+++E+    GG V
Sbjct: 436  TQVSRQWRKKAEV--TGTQIGSYFGASLCSVDVDSDGSTDLILIGAPHYYEQTR--GGQV 491

Query: 263  YVYLNQGGH--WAGISPLR-LCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GK 317
             V     G   W   + LR   G P   FG +L VLGD+N+D   D+A+GAP + +  G 
Sbjct: 492  SVCPLPRGRVQWQCDAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAPGEQENRGA 551

Query: 318  VFIYHGSS-LGVVAKPSQVLEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGSLADTAV 374
            V+++HG+S  G+    SQ +    +   ++ FG +LSG  D+  +   DL VG+     +
Sbjct: 552  VYLFHGASESGISPSHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDLAVGARGQ-VL 610

Query: 375  LFRARPILHVSHEVSIAPRSIDLEQPNC---------AGGHSVCVDLRVCFSYIAVPSSY 425
            L R+ P+L V   +  +P  +      C         AG  +VC+ ++   S +      
Sbjct: 611  LLRSLPVLKVGVAMRFSPVEVAKAVYRCWEEKPSALEAGDATVCLTIQK--SSLDQLGDI 668

Query: 426  SPTVALDYVLDAD--TDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMF 483
              +V  D  LD    T R +  +    T   R           T+ L       C     
Sbjct: 669  QSSVRFDLALDPGRLTSRAIFNETKNPTLTRRK----------TLGLGIH----CETLKL 714

Query: 484  QLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQG 543
             L + V+D +  I++ L++SL    +R   P      + P+L         A + F ++ 
Sbjct: 715  LLPDCVEDVVSPIILHLNFSL----VREPIPSP--QNLRPVLAVGSQDLFTASLPF-EKN 767

Query: 544  CGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPS 603
            CG+D +C+ +L +  +                     + L  L+    + L ++VT   +
Sbjct: 768  CGQDGLCEGDLGVTLS--------------------FSGLQTLTVGSSLELNVIVTVWNA 807

Query: 604  DPAQPQADGDDAHEAQLLVMLPDSLHYSGV---------RALDPAEKPLCLSNENASHVE 654
                    G+D++   + +  P  L +  V          AL  A + +   +E      
Sbjct: 808  --------GEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRSSR 859

Query: 655  CELGNPM-KRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELP 713
            C + +P+   G+  TF   + T  +S + T  +  L+ A+ S +     S++A   +ELP
Sbjct: 860  CSVNHPIFHEGSNGTF---IVTFDVSYKATLGDRMLMRASASSENNKASSSKATFQLELP 916

Query: 714  LSIAGMAI-----PQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFL 768
            +  A   +         +F+     E+ M+       + ++   V+N  Q    +   F 
Sbjct: 917  VKYAVYTMISRQEESTKYFNFATSDEKKMK-------EAEHRYRVNNLSQRDLAISINF- 968

Query: 769  NIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQ 828
               W   + NG                            +   DV         +E P Q
Sbjct: 969  ---WVPVLLNG----------------------------VAVWDV--------VMEAPSQ 989

Query: 829  QEP--GERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSC--PLYSFDRAAVLHVWG 884
              P   ER+ P  S +     +  ++  LDC+   A+C+ F C  P +S        + G
Sbjct: 990  SLPCVSERKPPQHSDF---LTQISRSPMLDCS--IADCLQFRCDVPSFSVQEELDFTLKG 1044

Query: 885  RL---WNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAE 941
             L   W    L+     K + V+  A IT  +S+ + +    + +   M  +     V  
Sbjct: 1045 NLSFGWVRETLQ-----KKVLVVSVAEITFDTSVYSQLPGQEAFMRAQMEMVLEEDEVYN 1099

Query: 942  GVPWWVILLAVLAGLLVLALLVLLLWKMGFFKR 974
             +P  +I+ + +  LL+LAL+   L+K+GFFKR
Sbjct: 1100 AIP--IIMGSSVGALLLLALITATLYKLGFFKR 1130


>gi|29171717 glycosylphosphatidylinositol specific phospholipase D1
           isoform 1 precursor [Homo sapiens]
          Length = 840

 Score = 71.2 bits (173), Expect = 5e-12
 Identities = 54/158 (34%), Positives = 79/158 (50%), Gaps = 22/158 (13%)

Query: 228 GYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRL------- 280
           G+++  ADLN DG  DL+VGAP +        G VY+     G+  G+ P+ L       
Sbjct: 382 GWAMTSADLNQDGHGDLVVGAPGYSRPGHIHIGRVYLIY---GNDLGLPPVDLDLDKEAH 438

Query: 281 ----CGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD------GKVFIYHGSSLGVVA 330
                  P   FG +LAVL D N DG PD+AVGAP  G       G V++Y GS  G ++
Sbjct: 439 RILEGFQPSGRFGSALAVL-DFNVDGVPDLAVGAPSVGSEQLTYKGAVYVYFGSKQGGMS 497

Query: 331 KPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGS 368
               +         + G++L  + D++G+  PDL++GS
Sbjct: 498 SSPNITISCQDIYCNLGWTLLAA-DVNGDSEPDLVIGS 534



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 59/164 (35%), Positives = 73/164 (44%), Gaps = 16/164 (9%)

Query: 217 MLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGIS 276
           +L G + +  FG +LAV D N DG PDL VGAP     Q    GAVYVY          S
Sbjct: 440 ILEGFQPSGRFGSALAVLDFNVDGVPDLAVGAPSVGSEQLTYKGAVYVYFGSKQGGMSSS 499

Query: 277 PLRLCGSPDSMFGISLAVL-GDLNQDGFPDIAVGAPF-DGDGK-----VFIYHGSSLG-- 327
           P       D    +   +L  D+N D  PD+ +G+PF  G GK        Y G SL   
Sbjct: 500 PNITISCQDIYCNLGWTLLAADVNGDSEPDLVIGSPFAPGGGKQKGIVAAFYSGPSLSDK 559

Query: 328 ---VVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGS 368
               V   +  + GE      FGYSL G + +D      LLVGS
Sbjct: 560 EKLNVEAANWTVRGEE-DFSWFGYSLHG-VTVDNRTL--LLVGS 599



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 19/62 (30%), Positives = 34/62 (54%), Gaps = 2/62 (3%)

Query: 191 GAPRANHKGAVVIL--RKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGA 248
           G+ +  +KGAV +    K       P + +S + +    G++L  AD+N D  PDL++G+
Sbjct: 475 GSEQLTYKGAVYVYFGSKQGGMSSSPNITISCQDIYCNLGWTLLAADVNGDSEPDLVIGS 534

Query: 249 PY 250
           P+
Sbjct: 535 PF 536



 Score = 31.2 bits (69), Expect = 5.3
 Identities = 47/186 (25%), Positives = 74/186 (39%), Gaps = 45/186 (24%)

Query: 92  QGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEA 151
           +G E F +           +   LL G+P    WK  +R+         L H+ D     
Sbjct: 572 RGEEDFSWFGYSLHGVTVDNRTLLLVGSP---TWKNASRL-------GHLLHIRD----- 616

Query: 152 GGEKEQDPRL---IPVPANSYF-----------GFSIDSGKGLVRAE-ELSFVAGAPRAN 196
             EK+   R+    P    S+F           G S+ SG  L+    +   + GAP  +
Sbjct: 617 --EKKSLGRVYGYFPPNGQSWFTISGDKAMGKLGTSLSSGHVLMNGTLKQVLLVGAPTYD 674

Query: 197 HKGAV----VILRKDSASRLV-------PEVM--LSGERLTSGFGYSLAVADLNSDGWPD 243
               V    V L +  A+R+        P ++   SG+R  S FG  L ++DL+ DG  +
Sbjct: 675 DVSKVAFLTVTLHQGGATRMYALTSDAQPLLLSTFSGDRRFSRFGGVLHLSDLDDDGLDE 734

Query: 244 LIVGAP 249
           +I+ AP
Sbjct: 735 IIMAAP 740


>gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo
           sapiens]
          Length = 462

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 116/469 (24%), Positives = 177/469 (37%), Gaps = 86/469 (18%)

Query: 541 KQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTN 600
           ++ CG D ICQ NL +                      G  +L   S    +  E+MV N
Sbjct: 17  EKNCGADHICQDNLGI-----------------SFSFPGLKSLLVGSNLE-LNAEVMVWN 58

Query: 601 LPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGV---------RALDPAEKPLCLSNENAS 651
                     DG+D++   +    P  L Y  V         R+L        + ++   
Sbjct: 59  ----------DGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTW 108

Query: 652 HVECELGNPMKRG-AQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFI 710
              C + + + RG AQ+TF   L+T  +S +    +  LL A +S +   P +++    +
Sbjct: 109 STSCRINHLIFRGGAQITF---LATFDVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQL 165

Query: 711 ELPLSIAGMAI-------PQQLFFSGVVRGER--AMQSERDVGSKVKYEVTVSNQGQSLR 761
           ELP+  A   +        + L FS     E   AM   +  G        V+N GQ  R
Sbjct: 166 ELPVKYAVYTVVSSHEQFTKYLNFSESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQ--R 223

Query: 762 TLGSAFLNIMWPHEI-ANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRR 820
            L  + +N   P E+     W    M VE+   Q P     C    +     +DS     
Sbjct: 224 DLPVS-INFWVPVELNQEAVW----MDVEVSHPQVPKD---CMWLLHECPFYLDSLCPMW 275

Query: 821 RELEPPEQ-------QEPGERQEPSMSWWPVSS--AEKKKNITLDCARGTANCVVFSC-- 869
               P E        Q P  R        P S   A  +KN  LDC+   A C+ F C  
Sbjct: 276 VPDVPAETLVLCIFPQNPSLRCSSEKIAPPASDFLAHIQKNPVLDCS--IAGCLRFRCDV 333

Query: 870 PLYSFDRAAVLHVWGRL---WNSTFLEEYSAVKSLEVIVRANITVKSSI-KNLMLRDAST 925
           P +S        + G L   W    L+     K + V+  A IT  +S+   L  ++A  
Sbjct: 334 PSFSVQEELDFTLKGNLSFGWVRQILQ-----KKVSVVSVAEITFDTSVYSQLPGQEAFM 388

Query: 926 VIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKR 974
                  L+   V     P  +I+ + + GLL+LAL+  +L+K+GFFKR
Sbjct: 389 RAQTTTVLEKYKVHN---PTPLIVGSSIGGLLLLALITAVLYKVGFFKR 434


>gi|169214874 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 583

 Score = 33.5 bits (75), Expect = 1.1
 Identities = 30/98 (30%), Positives = 40/98 (40%), Gaps = 30/98 (30%)

Query: 80  DGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTY-------------NWK 126
           DGG+W       +GHEQ        AA ++   HYL  GAPG +                
Sbjct: 72  DGGDW-------EGHEQ-------DAAQYAAQGHYLARGAPGDHVAIAHRRHGDDSPPVA 117

Query: 127 GTARVELCAQGSADLAHLDDGPYEAGG---EKEQDPRL 161
           G    EL A G   L  ++ G  E  G   E++Q+P L
Sbjct: 118 GRDAGELGAVGHLVLDDVEQGREEGDGHAEEEQQEPEL 155


>gi|169215109 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 583

 Score = 33.5 bits (75), Expect = 1.1
 Identities = 30/98 (30%), Positives = 40/98 (40%), Gaps = 30/98 (30%)

Query: 80  DGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTY-------------NWK 126
           DGG+W       +GHEQ        AA ++   HYL  GAPG +                
Sbjct: 72  DGGDW-------EGHEQ-------DAAQYAAQGHYLARGAPGDHVAIAHRRHGDDSPPVA 117

Query: 127 GTARVELCAQGSADLAHLDDGPYEAGG---EKEQDPRL 161
           G    EL A G   L  ++ G  E  G   E++Q+P L
Sbjct: 118 GRDAGELGAVGHLVLDDVEQGREEGDGHAEEEQQEPEL 155


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,491,350
Number of Sequences: 37866
Number of extensions: 2156462
Number of successful extensions: 5688
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 5329
Number of HSP's gapped (non-prelim): 101
length of query: 1044
length of database: 18,247,518
effective HSP length: 112
effective length of query: 932
effective length of database: 14,006,526
effective search space: 13054082232
effective search space used: 13054082232
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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