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Search of human proteins with 222418613
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|222418613 integrin alpha 7 isoform 1 precursor [Homo
sapiens]
(1141 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens] 2309 0.0
gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens] 2218 0.0
gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens] 2031 0.0
gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [... 1045 0.0
gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [... 1027 0.0
gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens] 629 e-180
gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] 619 e-177
gi|49170034 integrin, alpha 8 [Homo sapiens] 344 2e-94
gi|52485941 integrin, alpha 9 precursor [Homo sapiens] 320 5e-87
gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] 314 3e-85
gi|56237029 integrin alpha 5 precursor [Homo sapiens] 299 9e-81
gi|223468595 integrin alpha-V isoform 2 [Homo sapiens] 297 4e-80
gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens] 285 2e-76
gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] 282 1e-75
gi|67191027 integrin alpha 4 precursor [Homo sapiens] 248 2e-65
gi|31657142 integrin, alpha 1 precursor [Homo sapiens] 227 6e-59
gi|38569398 integrin, alpha 10 precursor [Homo sapiens] 184 4e-46
gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] 159 1e-38
gi|52485853 integrin, alpha 11 precursor [Homo sapiens] 158 3e-38
gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] 157 5e-38
gi|34452173 integrin alpha X precursor [Homo sapiens] 146 1e-34
gi|116295258 integrin alpha 2 precursor [Homo sapiens] 145 2e-34
gi|148728188 integrin, alpha E precursor [Homo sapiens] 145 3e-34
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 132 2e-30
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] 131 4e-30
gi|62548866 integrin, alpha D precursor [Homo sapiens] 124 7e-28
gi|29171717 glycosylphosphatidylinositol specific phospholipase ... 71 5e-12
gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo ... 47 1e-04
gi|169214874 PREDICTED: hypothetical protein [Homo sapiens] 33 1.2
gi|169215109 PREDICTED: hypothetical protein [Homo sapiens] 33 1.2
>gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]
Length = 1141
Score = 2309 bits (5984), Expect = 0.0
Identities = 1141/1141 (100%), Positives = 1141/1141 (100%)
Query: 1 MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHR 60
MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHR
Sbjct: 1 MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHR 60
Query: 61 QLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKE 120
QLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKE
Sbjct: 61 QLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKE 120
Query: 121 NQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE 180
NQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE
Sbjct: 121 NQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE 180
Query: 181 WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAH 240
WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAH
Sbjct: 181 WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAH 240
Query: 241 LDDGPYEAGGEKEQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVI 300
LDDGPYEAGGEKEQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVI
Sbjct: 241 LDDGPYEAGGEKEQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVI 300
Query: 301 LRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVY 360
LRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVY
Sbjct: 301 LRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVY 360
Query: 361 VYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHG 420
VYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHG
Sbjct: 361 VYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHG 420
Query: 421 SSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILH 480
SSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILH
Sbjct: 421 SSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILH 480
Query: 481 VSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRL 540
VSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRL
Sbjct: 481 VSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRL 540
Query: 541 RGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYS 600
RGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYS
Sbjct: 541 RGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYS 600
Query: 601 LQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCT 660
LQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCT
Sbjct: 601 LQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCT 660
Query: 661 RVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVM 720
RVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVM
Sbjct: 661 RVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVM 720
Query: 721 LPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETT 780
LPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETT
Sbjct: 721 LPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETT 780
Query: 781 ELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDV 840
ELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDV
Sbjct: 781 ELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDV 840
Query: 841 GSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCS 900
GSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCS
Sbjct: 841 GSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCS 900
Query: 901 PRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTAN 960
PRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTAN
Sbjct: 901 PRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTAN 960
Query: 961 CVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDA 1020
CVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDA
Sbjct: 961 CVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDA 1020
Query: 1021 STVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVP 1080
STVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVP
Sbjct: 1021 STVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVP 1080
Query: 1081 QYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGT 1140
QYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGT
Sbjct: 1081 QYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGT 1140
Query: 1141 A 1141
A
Sbjct: 1141 A 1141
>gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]
Length = 1137
Score = 2218 bits (5748), Expect = 0.0
Identities = 1109/1147 (96%), Positives = 1113/1147 (97%), Gaps = 16/1147 (1%)
Query: 1 MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHR 60
MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHR
Sbjct: 1 MAGARSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHR 60
Query: 61 QLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKE 120
QLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKE
Sbjct: 61 QLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKE 120
Query: 121 NQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE 180
NQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE
Sbjct: 121 NQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGE 180
Query: 181 WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAH 240
WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKG V +
Sbjct: 181 WKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFV----------TN 230
Query: 241 LDDGPYEAGGEKEQDPR-LIPVPA-----NSYFGFSIDSGKGLVRAEELSFVAGAPRANH 294
+D + K DP +P PA NSY GFSIDSGKGLVRAEELSFVAGAPRANH
Sbjct: 231 IDSSDPDQLVYKTLDPADRLPGPAGDLALNSYLGFSIDSGKGLVRAEELSFVAGAPRANH 290
Query: 295 KGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEE 354
KGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEE
Sbjct: 291 KGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEE 350
Query: 355 LGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGK 414
LGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGK
Sbjct: 351 LGGAVYVYLNQGGHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGK 410
Query: 415 VFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFR 474
VFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFR
Sbjct: 411 VFIYHGSSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFR 470
Query: 475 ARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDA 534
ARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDA
Sbjct: 471 ARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDA 530
Query: 535 DTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIV 594
DTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIV
Sbjct: 531 DTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIV 590
Query: 595 VTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLV 654
VTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLV
Sbjct: 591 VTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLV 650
Query: 655 RARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHE 714
RARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHE
Sbjct: 651 RARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHE 710
Query: 715 AQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSG 774
AQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSG
Sbjct: 711 AQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSG 770
Query: 775 ISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAM 834
ISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAM
Sbjct: 771 ISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAM 830
Query: 835 QSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPG 894
QSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPG
Sbjct: 831 QSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPG 890
Query: 895 QKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDC 954
QKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDC
Sbjct: 891 QKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDC 950
Query: 955 ARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKN 1014
ARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKN
Sbjct: 951 ARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKN 1010
Query: 1015 LMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKH 1074
LMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKH
Sbjct: 1011 LMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKH 1070
Query: 1075 PEATVPQYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDG 1134
PEATVPQYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDG
Sbjct: 1071 PEATVPQYHAVKIPREDRQQFKEEKTGTILRNNWGSPRREGPDAHPILAADGHPELGPDG 1130
Query: 1135 HPGPGTA 1141
HPGPGTA
Sbjct: 1131 HPGPGTA 1137
>gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]
Length = 1044
Score = 2031 bits (5263), Expect = 0.0
Identities = 1003/1003 (100%), Positives = 1003/1003 (100%)
Query: 139 TCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQ 198
TCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQ
Sbjct: 42 TCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQ 101
Query: 199 QGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRL 258
QGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRL
Sbjct: 102 QGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRL 161
Query: 259 IPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGE 318
IPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGE
Sbjct: 162 IPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGE 221
Query: 319 RLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLC 378
RLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLC
Sbjct: 222 RLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLC 281
Query: 379 GSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV 438
GSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV
Sbjct: 282 GSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV 341
Query: 439 GIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPN 498
GIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPN
Sbjct: 342 GIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPN 401
Query: 499 CAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPK 558
CAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPK
Sbjct: 402 CAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPK 461
Query: 559 HQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPV 618
HQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPV
Sbjct: 462 HQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPV 521
Query: 619 APILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTT 678
APILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTT
Sbjct: 522 APILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTT 581
Query: 679 ALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEK 738
ALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEK
Sbjct: 582 ALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEK 641
Query: 739 PLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHP 798
PLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHP
Sbjct: 642 PLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHP 701
Query: 799 VSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLR 858
VSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLR
Sbjct: 702 VSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLR 761
Query: 859 TLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRR 918
TLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRR
Sbjct: 762 TLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRR 821
Query: 919 ELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLH 978
ELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLH
Sbjct: 822 ELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLH 881
Query: 979 VWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAE 1038
VWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAE
Sbjct: 882 VWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAE 941
Query: 1039 GVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDRQQFKEE 1098
GVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDRQQFKEE
Sbjct: 942 GVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIPREDRQQFKEE 1001
Query: 1099 KTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA 1141
KTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA
Sbjct: 1002 KTGTILRNNWGSPRREGPDAHPILAADGHPELGPDGHPGPGTA 1044
>gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [Homo
sapiens]
Length = 1091
Score = 1045 bits (2701), Expect = 0.0
Identities = 538/1105 (48%), Positives = 748/1105 (67%), Gaps = 36/1105 (3%)
Query: 12 ASGICYLFGSLLVELLFSRAVAFNLDVM--GALRKEGEPGSLFGFSVALHRQLQPRPQSW 69
A +C L+ L LL AFNLD +RK G+PGSLFGFS+A+H QLQP +
Sbjct: 4 AGQLCLLY--LSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRL 61
Query: 70 LLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVR 129
LLVGAP+A ALP Q+ANRTGGL++C ++ C R++ D AD ESKE+QW+GV+V+
Sbjct: 62 LLVGAPRAEALPLQRANRTGGLYSCDITARGP-CTRIEFDNDADPTSESKEDQWMGVTVQ 120
Query: 130 SQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQ 189
SQGPGGK+VTCAHRYE RQ V+ E+RD+ GRC+VLSQ+L I D++DGG+W FC+GR +
Sbjct: 121 SQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLR 180
Query: 190 GHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAG 249
GHE+FG CQQG AA F+ D HY++FGAPGTYNWKG RVE D+ +DGPYE G
Sbjct: 181 GHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVG 240
Query: 250 GEKEQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKD-SASR 308
GE E D L+PVPANSY GFS+DSGKG+V +E++FV+GAPRANH GAVV+L++D ++
Sbjct: 241 GETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAH 300
Query: 309 LVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGH 368
L+PE + GE L S FGY +AV DLN DGW D+++GAP +F+R E+GGAVYVY+NQ G
Sbjct: 301 LLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGR 360
Query: 369 WAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAK 428
W + P+RL G+ DSMFGI++ +GD+NQDG+PDIAVGAP+D GKVFIYHGS+ G+ K
Sbjct: 361 WNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTK 420
Query: 429 PSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIA 488
P+QVL+G + FGYS++G++D+D N YPD+ VGSL+D+ +FR+RP++++ +++
Sbjct: 421 PTQVLKGIS---PYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVT 477
Query: 489 PRSIDLEQPNCAGGHS-VCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRV 547
P IDL Q G S +C+ ++ CF Y A P+ Y+P++++ L+A+ +RR G RV
Sbjct: 478 PNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRV 537
Query: 548 TFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLR 607
F ++ EPK+ T LK Q +VC + LQ+N++DKLR I +T S +Q P R
Sbjct: 538 QFRNQG-SEPKYTQELT--LKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSR 594
Query: 608 RQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTE- 666
R+ LP V PILN+ +P T ++HFLK+GCG+D +C SNL+L +FCTR + +
Sbjct: 595 RRV--NSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKL-EYKFCTREGNQDK 651
Query: 667 FQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLH 726
F LP+ G L L Q I LE+ VTN PS+P P DGDDAHEA+L+ PD+L
Sbjct: 652 FSYLPIQ-KGVPEL-VLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLT 709
Query: 727 YSGVRALD--PAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEV 784
YS R L P ++ C++N+N S +CELGNP KR + VTFYL+LST+ ++ +T +L++
Sbjct: 710 YSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDI 769
Query: 785 ELLLATISEQE-LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSK 843
L L T S Q+ L P++A+A+V IEL LS++G+A P Q++F G V GE+AM+SE +VGS
Sbjct: 770 NLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSL 829
Query: 844 VKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRP 903
++YE V N G+ L LG+A LNI WP EI+NGKWLLY ++VE +G +K C P+
Sbjct: 830 IEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKG----LEKVTCEPQK 885
Query: 904 NILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVV 963
I L++ R++ E E+Q R+ S ++K TL+C+ NCV
Sbjct: 886 EINSLNLTESHNSRKKREITEKQIDDNRK--------FSLFAERKYQTLNCS-VNVNCVN 936
Query: 964 FSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTV 1023
CPL D A L + RLWNSTFLEEYS + L++++RA I V ++ +N+ L +A T
Sbjct: 937 IRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQ 996
Query: 1024 IPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQYH 1083
+ V V+ GVPWW+IL+A+LAG+L+LALLV +LWK GFFKR+++ + +VP+YH
Sbjct: 997 VRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRSRYDD-SVPRYH 1055
Query: 1084 AVKIPREDRQQFKEEKTGTILRNNW 1108
AV+I +E+R+ E+ + + W
Sbjct: 1056 AVRIRKEEREIKDEKYIDNLEKKQW 1080
>gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [Homo
sapiens]
Length = 1073
Score = 1027 bits (2655), Expect = 0.0
Identities = 534/1086 (49%), Positives = 733/1086 (67%), Gaps = 40/1086 (3%)
Query: 12 ASGICYLFGSLLVELLFSRAVAFNLDVM--GALRKEGEPGSLFGFSVALHRQLQPRPQSW 69
A +C L+ L LL AFNLD +RK G+PGSLFGFS+A+H QLQP +
Sbjct: 4 AGQLCLLY--LSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRL 61
Query: 70 LLVGAPQALALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVR 129
LLVGAP+A ALP Q+ANRTGGL++C ++ C R++ D AD ESKE+QW+GV+V+
Sbjct: 62 LLVGAPRAEALPLQRANRTGGLYSCDITARGP-CTRIEFDNDADPTSESKEDQWMGVTVQ 120
Query: 130 SQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQ 189
SQGPGGK+VTCAHRYE RQ V+ E+RD+ GRC+VLSQ+L I D++DGG+W FC+GR +
Sbjct: 121 SQGPGGKVVTCAHRYEKRQHVNTKQESRDIFGRCYVLSQNLRIEDDMDGGDWSFCDGRLR 180
Query: 190 GHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAG 249
GHE+FG CQQG AA F+ D HY++FGAPGTYNWKG RVE D+ +DGPYE G
Sbjct: 181 GHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRVEQKNNTFFDMNIFEDGPYEVG 240
Query: 250 GEKEQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKD-SASR 308
GE E D L+PVPANSY GFS+DSGKG+V +E++FV+GAPRANH GAVV+L++D ++
Sbjct: 241 GETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGAVVLLKRDMKSAH 300
Query: 309 LVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGH 368
L+PE + GE L S FGY +AV DLN DGW D+++GAP +F+R E+GGAVYVY+NQ G
Sbjct: 301 LLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVGGAVYVYMNQQGR 360
Query: 369 WAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAK 428
W + P+RL G+ DSMFGI++ +GD+NQDG+PDIAVGAP+D GKVFIYHGS+ G+ K
Sbjct: 361 WNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDDLGKVFIYHGSANGINTK 420
Query: 429 PSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIA 488
P+QVL+G + FGYS++G++D+D N YPD+ VGSL+D+ +FR+RP++++ +++
Sbjct: 421 PTQVLKGIS---PYFGYSIAGNMDLDRNSYPDVAVGSLSDSVTIFRSRPVINIQKTITVT 477
Query: 489 PRSIDLEQPNCAGGHS-VCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRV 547
P IDL Q G S +C+ ++ CF Y A P+ Y+P++++ L+A+ +RR G RV
Sbjct: 478 PNRIDLRQKTACGAPSGICLQVKSCFEYTANPAGYNPSISIVGTLEAEKERRKSGLSSRV 537
Query: 548 TFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLR 607
F ++ EPK+ T LK Q +VC + LQ+N++DKLR I +T S +Q P R
Sbjct: 538 QFRNQG-SEPKYTQELT--LKRQKQKVCMEETLWLQDNIRDKLRPIPITASVEIQEPSSR 594
Query: 608 RQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTE- 666
R+ LP V PILN+ +P T ++HFLK+GCG+D +C SNL+L +FCTR + +
Sbjct: 595 RRV--NSLPEVLPILNSDEPKTAHIDVHFLKEGCGDDNVCNSNLKL-EYKFCTREGNQDK 651
Query: 667 FQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLH 726
F LP+ G L L Q I LE+ VTN PS+P P DGDDAHEA+L+ PD+L
Sbjct: 652 FSYLPIQ-KGVPEL-VLKDQKDIALEITVTNSPSNPRNPTKDGDDAHEAKLIATFPDTLT 709
Query: 727 YSGVRALD--PAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEV 784
YS R L P ++ C++N+N S +CELGNP KR + VTFYL+LST+ ++ +T +L++
Sbjct: 710 YSAYRELRAFPEKQLSCVANQNGSQADCELGNPFKRNSNVTFYLVLSTTEVTFDTPDLDI 769
Query: 785 ELLLATISEQE-LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSK 843
L L T S Q+ L P++A+A+V IEL LS++G+A P Q++F G V GE+AM+SE +VGS
Sbjct: 770 NLKLETTSNQDNLAPITAKAKVVIELLLSVSGVAKPSQVYFGGTVVGEQAMKSEDEVGSL 829
Query: 844 VKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRP 903
++YE V N G+ L LG+A LNI WP EI+NGKWLLY ++VE +G +K C P+
Sbjct: 830 IEYEFRVINLGKPLTNLGTATLNIQWPKEISNGKWLLYLVKVESKG----LEKVTCEPQK 885
Query: 904 NILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVV 963
I L++ R++ E E+Q R+ S ++K TL+C+ NCV
Sbjct: 886 EINSLNLTESHNSRKKREITEKQIDDNRK--------FSLFAERKYQTLNCS-VNVNCVN 936
Query: 964 FSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTV 1023
CPL D A L + RLWNSTFLEEYS + L++++RA I V ++ +N+ L +A T
Sbjct: 937 IRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDVTAAAENIRLPNAGTQ 996
Query: 1024 IPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK--HPEATVPQ 1081
+ V V+ GVPWW+IL+A+LAG+L+LALLV +LWK GFFKR K H +AT
Sbjct: 997 VRVTVFPSKTVAQYSGVPWWIILVAILAGILMLALLVFILWKCGFFKRNKKDHYDAT--- 1053
Query: 1082 YHAVKI 1087
YH +I
Sbjct: 1054 YHKAEI 1059
>gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]
Length = 1066
Score = 629 bits (1622), Expect = e-180
Identities = 405/1091 (37%), Positives = 604/1091 (55%), Gaps = 112/1091 (10%)
Query: 33 AFNLDVMGALRKE-GEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGL 91
AFNLD + KE G PGSLFG+SVALHRQ + + + LL GAP+ LA+P NRTG +
Sbjct: 32 AFNLDTRFLVVKEAGNPGSLFGYSVALHRQTERQQRYLLLAGAPRELAVPDGYTNRTGAV 91
Query: 92 FACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVD 151
+ CPL+ + DC R++I D E+ WLGV+V SQGP G+++ CAHRY
Sbjct: 92 YLCPLTAHKDDCERMNITVKNDPGHHIIEDMWLGVTVASQGPAGRVLVCAHRY------T 145
Query: 152 QIL-----ETRDMIGRCFVLSQDLAIRDELDGG-EW-----KFCEGRPQGHEQFGFCQQG 200
Q+L + R M+G+C+V DL ELD +W + C + + G CQ G
Sbjct: 146 QVLWSGSEDQRRMVGKCYVRGNDL----ELDSSDDWQTYHNEMCNSNTD-YLETGMCQLG 200
Query: 201 TAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIP 260
T+ F+ ++ Y FGAPG YNWKG + + + ++ +DP
Sbjct: 201 TSGGFTQNTVY--FGAPGAYNWKGNSYM------------IQRKEWDLSEYSYKDPE--- 243
Query: 261 VPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERL 320
N Y G+++ G ++ + ++ V GAPR H GAV +L +++ L +L G ++
Sbjct: 244 DQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQV 303
Query: 321 TSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISP-LRLCG 379
+ FG ++A+ADLN+DGW DL+VGAPY+FER+EE+GGA+YV++NQ G P L L G
Sbjct: 304 GAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHG 363
Query: 380 SPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV- 438
S FG+S+A +GD+NQDGF DIAVGAPF+G GKV+IYH SS G++ +P QV+ GE +
Sbjct: 364 PSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGEKLG 423
Query: 439 --GIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQ 496
G+ +FGYSLSG +D+D N YPDLLVGSL+D VL RARP++++ H+ ++ PR L+
Sbjct: 424 LPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHK-TLVPRPAVLDP 482
Query: 497 PNCAGGHSVCVDLRVCFSY--IAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNL 554
C + CV + +CF+Y A +Y + L Y L+AD DRR PR+ F
Sbjct: 483 ALCTA--TSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRR----PPRLRFAG--- 533
Query: 555 EEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQG 614
+++ + C L +N++DKLR I+++++YSL R G
Sbjct: 534 ----SESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLR 589
Query: 615 LPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDV 674
PILN Q E+ F K+ CG D C+SNLQ+ RA F + + L
Sbjct: 590 SLDAYPILNQAQALENHTEVQFQKE-CGPDNKCESNLQM-RAAFVSE-QQQKLSRLQYSR 646
Query: 675 DGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALD 734
D L L + VTN + + G+DAHEA L +++P +L S VR
Sbjct: 647 DVRKLL----------LSINVTNTRTS----ERSGEDAHEALLTLVVPPALLLSSVR--- 689
Query: 735 PAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQ 794
C +NE + CELGNP KR ++ + G+++ T +L+V+L L+T S Q
Sbjct: 690 --PPGACQANET---IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQ 744
Query: 795 E-LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQ 853
+ L P+ V L S++ + Q FF G V GE M++ DVGS +KYE V
Sbjct: 745 DNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPM 804
Query: 854 GQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEG-GQGPGQKGLCSPRPNILH-LDV- 910
G+ L LG+ L + WP+E++NGKWLLYP ++ + G G P C P ++++ L++
Sbjct: 805 GEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWP-----CRPPGDLINPLNLT 859
Query: 911 --------DSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNIT-LDCARGTANC 961
S RRRR+L+P Q P P ++ +++A+K K+ T L CA G A+C
Sbjct: 860 LSDPGDRPSSPQRRRRQLDPGGGQGP-----PPVT---LAAAKKAKSETVLTCATGRAHC 911
Query: 962 VVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDAS 1021
V CP+ + V R+WNSTF+E+Y + V A + +++SI + + + +
Sbjct: 912 VWLECPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKT 971
Query: 1022 TVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPEATVPQ 1081
T V + + + + + W++L+AV AGLL+L L++LLLWK FFKR ++ + +P+
Sbjct: 972 TWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCDFFKRTRYYQ-IMPK 1030
Query: 1082 YHAVKIPREDR 1092
YHAV+I E+R
Sbjct: 1031 YHAVRIREEER 1041
>gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]
Length = 1051
Score = 619 bits (1597), Expect = e-177
Identities = 399/1072 (37%), Positives = 592/1072 (55%), Gaps = 111/1072 (10%)
Query: 33 AFNLDVMGALRKE-GEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGL 91
AFNLD + KE G PGSLFG+SVALHRQ + + + LL GAP+ LA+P NRTG +
Sbjct: 32 AFNLDTRFLVVKEAGNPGSLFGYSVALHRQTERQQRYLLLAGAPRELAVPDGYTNRTGAV 91
Query: 92 FACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVD 151
+ CPL+ + DC R++I D E+ WLGV+V SQGP G+++ CAHRY
Sbjct: 92 YLCPLTAHKDDCERMNITVKNDPGHHIIEDMWLGVTVASQGPAGRVLVCAHRY------T 145
Query: 152 QIL-----ETRDMIGRCFVLSQDLAIRDELDGG-EW-----KFCEGRPQGHEQFGFCQQG 200
Q+L + R M+G+C+V DL ELD +W + C + + G CQ G
Sbjct: 146 QVLWSGSEDQRRMVGKCYVRGNDL----ELDSSDDWQTYHNEMCNSNTD-YLETGMCQLG 200
Query: 201 TAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIP 260
T+ F+ ++ Y FGAPG YNWKG + + + ++ +DP
Sbjct: 201 TSGGFTQNTVY--FGAPGAYNWKGNSYM------------IQRKEWDLSEYSYKDPE--- 243
Query: 261 VPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERL 320
N Y G+++ G ++ + ++ V GAPR H GAV +L +++ L +L G ++
Sbjct: 244 DQGNLYIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLLSQEAGGDLRRRQVLEGSQV 303
Query: 321 TSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISP-LRLCG 379
+ FG ++A+ADLN+DGW DL+VGAPY+FER+EE+GGA+YV++NQ G P L L G
Sbjct: 304 GAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQAGTSFPAHPSLLLHG 363
Query: 380 SPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV- 438
S FG+S+A +GD+NQDGF DIAVGAPF+G GKV+IYH SS G++ +P QV+ GE +
Sbjct: 364 PSGSAFGLSVASIGDINQDGFQDIAVGAPFEGLGKVYIYHSSSKGLLRQPQQVIHGEKLG 423
Query: 439 --GIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQ 496
G+ +FGYSLSG +D+D N YPDLLVGSL+D VL RARP++++ H+ ++ PR L+
Sbjct: 424 LPGLATFGYSLSGQMDVDENFYPDLLVGSLSDHIVLLRARPVINIVHK-TLVPRPAVLDP 482
Query: 497 PNCAGGHSVCVDLRVCFSY--IAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNL 554
C + CV + +CF+Y A +Y + L Y L+AD DRR PR+ F
Sbjct: 483 ALCTA--TSCVQVELCFAYNQSAGNPNYRRNITLAYTLEADRDRR----PPRLRFAG--- 533
Query: 555 EEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQG 614
+++ + C L +N++DKLR I+++++YSL R G
Sbjct: 534 ----SESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIISMNYSLPLRMPDRPRLGLR 589
Query: 615 LPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDV 674
PILN Q E+ F K+ CG D C+SNLQ+ RA F + + L
Sbjct: 590 SLDAYPILNQAQALENHTEVQFQKE-CGPDNKCESNLQM-RAAFVSE-QQQKLSRLQYSR 646
Query: 675 DGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALD 734
D L L + VTN + + G+DAHEA L +++P +L S VR
Sbjct: 647 DVRKLL----------LSINVTNTRTS----ERSGEDAHEALLTLVVPPALLLSSVR--- 689
Query: 735 PAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQ 794
C +NE + CELGNP KR ++ + G+++ T +L+V+L L+T S Q
Sbjct: 690 --PPGACQANET---IFCELGNPFKRNQRMELLIAFEVIGVTLHTRDLQVQLQLSTSSHQ 744
Query: 795 E-LHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQ 853
+ L P+ V L S++ + Q FF G V GE M++ DVGS +KYE V
Sbjct: 745 DNLWPMILTLLVDYTLQTSLSMVNHRLQSFFGGTVMGESGMKTVEDVGSPLKYEFQVGPM 804
Query: 854 GQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEG-GQGPGQKGLCSPRPNILH-LDV- 910
G+ L LG+ L + WP+E++NGKWLLYP ++ + G G P C P ++++ L++
Sbjct: 805 GEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITVHGNGSWP-----CRPPGDLINPLNLT 859
Query: 911 --------DSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNIT-LDCARGTANC 961
S RRRR+L+P Q P P ++ +++A+K K+ T L CA G A+C
Sbjct: 860 LSDPGDRPSSPQRRRRQLDPGGGQGP-----PPVT---LAAAKKAKSETVLTCATGRAHC 911
Query: 962 VVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDAS 1021
V CP+ + V R+WNSTF+E+Y + V A + +++SI + + + +
Sbjct: 912 VWLECPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKT 971
Query: 1022 TVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK 1073
T V + + + + + W++L+AV AGLL+L L++LLLWK GFFKRA+
Sbjct: 972 TWFSVDIDSELVEELPAEIELWLVLVAVGAGLLLLGLIILLLWKCGFFKRAR 1023
>gi|49170034 integrin, alpha 8 [Homo sapiens]
Length = 1063
Score = 344 bits (883), Expect = 2e-94
Identities = 340/1167 (29%), Positives = 528/1167 (45%), Gaps = 174/1167 (14%)
Query: 1 MAGARSRDPWGASG-----ICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFS 55
M+ SR P G+ +C +L + L AFNLDV G GS FG++
Sbjct: 1 MSPGASRGPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYA 60
Query: 56 VALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFACPLSLE-ETDCYRVDID----- 109
V H + + +LVGAP+A G ++ CP E C ++ D
Sbjct: 61 VDFH--IPDARTASVLVGAPKANTSQPDIVEG-GAVYYCPWPAEGSAQCRQIPFDTTNNR 117
Query: 110 ----QGADMQKESKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFV 165
G E K NQW G +V++ GK+V CA Y R + +D +G C+V
Sbjct: 118 KIRVNGTKEPIEFKSNQWFGATVKAHK--GKVVACAPLYHWRTL--KPTPEKDPVGTCYV 173
Query: 166 LSQDLAIRDELDGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGT 225
Q+ + E+ C E G+CQ G + F + L+ G PG++ W+G
Sbjct: 174 AIQNFSAY-----AEFSPCRNSNADPEGQGYCQAGFSLDFYKNGD-LIVGGPGSFYWQGQ 227
Query: 226 ARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPAN---SYFGFSIDSGKGLVRAEE 282
A A+ + D + GEK+ + PA+ SY G+S+ +G+ +++
Sbjct: 228 VITASVADIIANYS-FKDILRKLAGEKQTEV----APASYDDSYLGYSVAAGEFTGDSQQ 282
Query: 283 LSFVAGAPR-ANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDL 341
VAG PR A + G V I+ + + +GE++ S FGY++ V+D+NSDG D+
Sbjct: 283 -ELVAGIPRGAQNFGYVSIINSTDMTFIQN---FTGEQMASYFGYTVVVSDVNSDGLDDV 338
Query: 342 IVGAPYFFERQEELG----GAVYVYLNQGGHWAGISPLRLCGSPD-SMFGISLAVLGDLN 396
+VGAP F ER+ E G +Y+YL Q P L G+ FG ++A LGDLN
Sbjct: 339 LVGAPLFMEREFESNPREVGQIYLYL-QVSSLLFRDPQILTGTETFGRFGSAMAHLGDLN 397
Query: 397 QDGFPDIAVGAPFDGD---GKVFIYHGSSLGVVAKPSQVLEG----EAVGIKSFGYSLSG 449
QDG+ DIA+G PF G GKV IY+G+ G+ KPSQVL+G AV FG++L G
Sbjct: 398 QDGYNDIAIGVPFAGKDQRGKVLIYNGNKDGLNTKPSQVLQGVWASHAVP-SGFGFTLRG 456
Query: 450 SLDMDGNQYPDLLVGSLADTAV-LFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSV--- 505
D+D N YPDL+VG+ V ++RARP++ V ++ + P I+LE C S+
Sbjct: 457 DSDIDKNDYPDLIVGAFGTGKVAVYRARPVVTVDAQLLLHPMIINLENKTCQVPDSMTSA 516
Query: 506 -CVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGT 564
C LRVC S S + T+ L + D+ ++ +G + R FL HQA
Sbjct: 517 ACFSLRVCAS--VTGQSIANTIVLMAEVQLDSLKQ-KGAIKRTLFLD------NHQAHRV 567
Query: 565 --VWLKHQHDRVCGDAMFQLQENV--KDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAP 620
+ +K Q C D + L++ +DKL I ++L+YSL + +GL V P
Sbjct: 568 FPLVIKRQKSHQCQDFIVYLRDETEFRDKLSPINISLNYSLDESTFK-----EGL-EVKP 621
Query: 621 ILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTAL 680
ILN ++ + + H L CGED +C +L+L +
Sbjct: 622 ILNYYRENIVSEQAHILVD-CGEDNLCVPDLKL-------------------------SA 655
Query: 681 FALSGQPVIGLE---LMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAE 737
Q +IG E +++ N + +G+ A+EA+L VM+P+ Y G+ +
Sbjct: 656 RPDKHQVIIGDENHLMLIIN-------ARNEGEGAYEAELFVMIPEEADYVGIERNNKGF 708
Query: 738 KPLC--LSNENASH-VECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLATISEQ 794
+PL EN + V C+LGNPM G + L + +E T + + L S
Sbjct: 709 RPLSCEYKMENVTRMVVCDLGNPMVSGTNYSLGLRFAVP--RLEKTNMSINFDLQIRSSN 766
Query: 795 ELHP----VSARARVFIELPLSIAGMAIPQQLFFS-GVVRGERAMQSERDVGSKVKYEVT 849
+ +P VS + + + I G++ P Q+ E E +VG V++
Sbjct: 767 KDNPDSNFVSLQINITAVAQVEIRGVSHPPQIVLPIHNWEPEEEPHKEEEVGPLVEHIYE 826
Query: 850 VSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLD 909
+ N G S T+ L + WP A ++LLY ++ GP Q C P PNI
Sbjct: 827 LHNIGPS--TISDTILEVGWPFS-ARDEFLLYIFHIQT---LGPLQ---CQPNPNI---- 873
Query: 910 VDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNI------------TLDCARG 957
++++P E + + +K+++ L+C
Sbjct: 874 ------NPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVEFHRQSPAKILNCT-- 925
Query: 958 TANCVVFSCPLYSFD--RAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANI-TVKSSIKN 1014
C+ SC + + +AVL V RLW TFL+ + +L +V + + + +
Sbjct: 926 NIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKNDPYALASLVSFEVKKMPYTDQP 985
Query: 1015 LMLRDASTVIPV-MVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK 1073
L + S I +++ P V+ +P WVI+LA+L GLLVLA+L L LWK GFF RA+
Sbjct: 986 AKLPEGSIAIKTSVIWATPN--VSFSIPLWVIILAILLGLLVLAILTLALWKCGFFDRAR 1043
Query: 1074 HPEATVPQYHAVKIPREDRQQFKEEKT 1100
P+ + DR+Q +KT
Sbjct: 1044 PPQEDM----------TDREQLTNDKT 1060
>gi|52485941 integrin, alpha 9 precursor [Homo sapiens]
Length = 1035
Score = 320 bits (820), Expect = 5e-87
Identities = 310/1109 (27%), Positives = 523/1109 (47%), Gaps = 152/1109 (13%)
Query: 9 PWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQS 68
P GA + L +L+V + A A+NLD + +G S FG++V H R
Sbjct: 7 PRGAGRLRALLLALVVAGI--PAGAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTR--- 61
Query: 69 WLLVGAPQALALPGQQANRTGGLFACPLSLE-ETDCYRVDIDQGADMQ-------KESKE 120
W+LVGAP+A + G +F C + + C +D+ +G + +E ++
Sbjct: 62 WVLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRD 121
Query: 121 NQWLGVSVRSQGPG-GKIVTCAHRYE-ARQRVDQILETRDMIGRCFVLSQDLAIRDELDG 178
++W+GVS+ Q G+++ CAHR++ D IL G C+++ +L + G
Sbjct: 122 DEWMGVSLARQPKADGRVLACAHRWKNIYYEADHILPH----GFCYIIPSNLQAK----G 173
Query: 179 GEWKFC--EGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSA 236
C E + + E+ G CQ G A F+ + ++ GAPG++ W GT +V
Sbjct: 174 RTLIPCYEEYKKKYGEEHGSCQAGIAGFFTEE--LVVMGAPGSFYWAGTIKV-------- 223
Query: 237 DLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKG 296
+L D Y + + +I +Y G+++ +G + V GAP+ G
Sbjct: 224 --LNLTDNTY-----LKLNDEVIMNRRYTYLGYAVTAGH-FSHPSTIDVVGGAPQDKGIG 275
Query: 297 AVVILRKDSAS-RLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEEL 355
V I R D S L+ SG+++ S FG SL DLN DG DL+VGAP F E ++E
Sbjct: 276 KVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSEIRDE- 334
Query: 356 GGAVYVYLNQG-GHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD-- 412
G V VY+N+G G L G+ ++ FG S+A L DL+ DGFPD+A+GAP + D
Sbjct: 335 -GQVTVYINRGNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFA 393
Query: 413 GKVFIYHGSSLGVVAKPSQVLEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGS-LADT 469
G V+IYHG + G+V + S L G+ + ++ FG S+SG +DMDGN YPD+ VG+ ++D+
Sbjct: 394 GAVYIYHGDAGGIVPQYSMKLSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDS 453
Query: 470 AVLFRARPILHVSHEVSI-APRSIDLEQPNCAGGHSV--CVDLRVCFSYIA--VPSSYSP 524
VL RARP++ V +VSI P SI++ P C G C+++ CFS+ VP
Sbjct: 454 VVLLRARPVITV--DVSIFLPGSINITAPQCHDGQQPVNCLNVTTCFSFHGKHVPGE--- 508
Query: 525 TVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQE 584
+ L+YVL AD ++ +GQ+PRV F+ L E Q + + L + + C + ++
Sbjct: 509 -IGLNYVLMADVAKKEKGQMPRVYFVL--LGETMGQVTEKLQLTYM-EETCRHYVAHVKR 564
Query: 585 NVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPIL--NAHQPSTQRAEIHFLKQGCG 642
V+D + IV +YSL + + LPP+ P+L Q Q+ + F +
Sbjct: 565 RVQDVISPIVFEAAYSLSEHVTGEEE--RELPPLTPVLRWKKGQKIAQKNQTVFERNCRS 622
Query: 643 EDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDP 702
ED C ++LQL + + L +D T AL I L + ++NL
Sbjct: 623 ED--CAADLQL------------QGKLLLSSMDEKTLYLALGAVKNISLNISISNL---- 664
Query: 703 AQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNP-MKRG 761
GDDA++A + + L + + E + + ++C +G P M+
Sbjct: 665 ------GDDAYDANVSFNVSRELFF--INMWQKEEMGISCELLESDFLKCSVGFPFMRSK 716
Query: 762 AQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFI-----ELPLSIAGM 816
++ F +I TS +S E L + + + + + V + E+ SI G+
Sbjct: 717 SKYEFSVIFDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGI 776
Query: 817 AIPQQLFFSGVVRGERAMQSERDVG---SKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEI 873
P + V +Q + D+ + + V N G S TL + ++I +P+ +
Sbjct: 777 MSPTSFVYGESVDAANFIQLD-DLECHFQPINITLQVYNTGPS--TLPGSSVSISFPNRL 833
Query: 874 ANGKWLLYPMQVELEGGQGPGQKGLCS----PRPNILHLDVDSRDRRRRELEPPEQQEPG 929
++G ++ +Q E+ GQ +KG CS P P I+ P++QE
Sbjct: 834 SSGGAEMFHVQ-EMVVGQ---EKGNCSFQKNPTPCII----------------PQEQE-- 871
Query: 930 ERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSF--DRAAVLHVWGRLWNST 987
++ + K LDC + +C+ C + + + + ++ L N+
Sbjct: 872 -----NIFHTIFAFFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESRTIDIY-MLLNTE 925
Query: 988 FLEEYSAVKSLEVIVRANITVKSSIKNLML-----RDASTVIPVMVYLDPMAVVAEGVPW 1042
L++ S+ ++ + RA + V +++ + + + + V + L+P V
Sbjct: 926 ILKKDSS-SVIQFMSRAKVKVDPALRVVEIAHGNPEEVTVVFEALHNLEPRGYVV----G 980
Query: 1043 WVILLAVLAGLLVLALLVLLLWKMGFFKR 1071
W+I +++L G+L+ LL +LLWKMGFF+R
Sbjct: 981 WIIAISLLVGILIFLLLAVLLWKMGFFRR 1009
>gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]
Length = 1048
Score = 314 bits (804), Expect = 3e-85
Identities = 319/1119 (28%), Positives = 510/1119 (45%), Gaps = 143/1119 (12%)
Query: 5 RSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQP 64
R R G G+ L LL+ L AFNLDV G GS FGF+V
Sbjct: 6 RRRLRLGPRGLPLLLSGLLLPL----CRAFNLDVDSPAEYSGPEGSYFGFAVDFFVP-SA 60
Query: 65 RPQSWLLVGAPQA-LALPGQQANRTGGLFACPLSLEETDCYRVDIDQ------GADMQKE 117
+ +LLVGAP+A PG G + C S C ++ D D E
Sbjct: 61 SSRMFLLVGAPKANTTQPGIVEG--GQVLKCDWSSTRR-CQPIEFDATGNRDYAKDDPLE 117
Query: 118 SKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELD 177
K +QW G SVRS+ KI+ CA Y R + Q R+ +G CF ++D
Sbjct: 118 FKSHQWFGASVRSKQD--KILACAPLYHWRTEMKQ---EREPVGTCF-------LQDGTK 165
Query: 178 GGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSAD 237
E+ C + + GFCQ G + F+ LL G PG++ W+G + Q +
Sbjct: 166 TVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLL-GGPGSFYWQGQL---ISDQVAEI 221
Query: 238 LAHLDDGPYEAGGEKEQDPRLIP-VPANSYFGFSID----SGKGLVRAEELSFVAGAPRA 292
++ D Y + R + +SY G+S+ +G G+ FV+G PRA
Sbjct: 222 VSKYDPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGID-----DFVSGVPRA 276
Query: 293 NHK-GAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFER 351
G V I + S L +GE++ + FG+S+A D+N D + D+ +GAP F +R
Sbjct: 277 ARTLGMVYIYDGKNMSSLYN---FTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDR 333
Query: 352 QEELG----GAVYVYLNQGGHWAGISPLRLCG-SPDSMFGISLAVLGDLNQDGFPDIAVG 406
+ G V V L + +L G + FG ++A LGDL+QDGF DIA+
Sbjct: 334 GSDGKLQEVGQVSVSLQRAS--GDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIA 391
Query: 407 APFDGDGK---VFIYHGSSLGVVAKPSQVLEGEAVGIK---SFGYSLSGSLDMDGNQYPD 460
AP+ G+ K V+I++G S G+ A PSQ+LEG+ SFGYS+ G+ D+D N YPD
Sbjct: 392 APYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPD 451
Query: 461 LLVGSL-ADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSV----CVDLRVCFSY 515
L+VG+ D A+L+RARP++ V+ + + P ++ + C+ + C ++R C
Sbjct: 452 LIVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLK- 510
Query: 516 IAVPSSYSPTVALDYVLDADTDR-RLRGQVPRVTFL-SRNLEEPKHQASGTVWLKHQHDR 573
A P L++ ++ D+ + +G + R FL SR+ K+ L +
Sbjct: 511 -ADGKGVLPR-KLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEEL 568
Query: 574 VCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAE 633
+ A + + +DKL I + + Y L R A GL PILN P+ +
Sbjct: 569 I---AYLRDESEFRDKLTPITIFMEYRLD---YRTAADTTGL---QPILNQFTPANISRQ 619
Query: 634 IHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLEL 693
H L CGED +C+ L++ D++ + + + D L
Sbjct: 620 AHILLD-CGEDNVCKPKLEV--------SVDSDQKKIYIGDDNPLTLI------------ 658
Query: 694 MVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPL--CLSNENAS-HV 750
+ Q G+ A+EA+L+V +P + GV + A L EN + V
Sbjct: 659 ---------VKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQV 709
Query: 751 ECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLL--ATISEQELHPVSARARVFIE 808
C+LGNPMK G Q+ L S S T ++ +L + + + ++ VS + + +
Sbjct: 710 VCDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVL 769
Query: 809 LPLSIAGMAIPQQLFFSGVVRGERA--MQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLN 866
+ I G++ P +F + E ++E DVG V++ + N G S + A L+
Sbjct: 770 AAVEIRGVSSPDHIFLP-IPNWEHKENPETEEDVGPVVQHIYELRNNGPS--SFSKAMLH 826
Query: 867 IMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQ 926
+ WP++ N LLY + +++G P ++++ + L+ E+
Sbjct: 827 LQWPYKY-NNNTLLYILHYDIDG-----------PMNCTSDMEINPLRIKISSLQTTEKN 874
Query: 927 E--PGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDR--AAVLHVWGR 982
+ G+ + + + + TL C G A C+ C + DR +A+L+V
Sbjct: 875 DTVAGQGERDHLITKRDLALSEGDIHTLGC--GVAQCLKIVCQVGRLDRGKSAILYVKSL 932
Query: 983 LWNSTFLEEYSAVKSLEVIVRANITV-KSSIKNLMLRDA--STVIPVMVY--LDPMAVVA 1037
LW TF+ + + S + A+ V + KNL + D ST++ V + P +
Sbjct: 933 LWTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPM-- 990
Query: 1038 EGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPE 1076
VP WVI+LAVLAGLL+LA+LV ++++MGFFKR + P+
Sbjct: 991 -PVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQ 1028
>gi|56237029 integrin alpha 5 precursor [Homo sapiens]
Length = 1049
Score = 299 bits (766), Expect = 9e-81
Identities = 324/1115 (29%), Positives = 490/1115 (43%), Gaps = 164/1115 (14%)
Query: 30 RAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQA-LALPGQQANRT 88
R FNLD G PGS FGFSV +R +LVGAP+A + PG +
Sbjct: 38 RVGGFNLDAEAPAVLSGPPGSFFGFSVEFYRPGTDGVS--VLVGAPKANTSQPG--VLQG 93
Query: 89 GGLFACPLSLEETDCYRVDIDQGADMQKES-------------KENQWLGVSVRSQGPGG 135
G ++ CP T C ++ D ES K QW G +VR+ G
Sbjct: 94 GAVYLCPWGASPTQCTPIEFDSKGSRLLESSLSSSEGEEPVEYKSLQWFGATVRAHG--S 151
Query: 136 KIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGHEQFG 195
I+ CA Y R + + D +G C+ LS D R E+ C G
Sbjct: 152 SILACAPLYSWRTEKEPL---SDPVGTCY-LSTDNFTRIL----EYAPCRSDFSWAAGQG 203
Query: 196 FCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQD 255
+CQ G +A F+ +L G PG+Y W+G ++ Q ++ + + Q
Sbjct: 204 YCQGGFSAEFTKTGRVVL-GGPGSYFWQG--QILSATQEQIAESYYPEYLINLVQGQLQT 260
Query: 256 PRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVML 315
+ + +SY G+S+ G+ E FVAG P+ N V + S R +
Sbjct: 261 RQASSIYDDSYLGYSVAVGEFSGDDTE-DFVAGVPKGNLTYGYVTILNGSDIRSLYN--F 317
Query: 316 SGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFER----QEELGGAVYVYLNQGGHWAG 371
SGE++ S FGY++A D+N DG DL+VGAP +R + + G VYVYL H AG
Sbjct: 318 SGEQMASYFGYAVAATDVNGDGLDDLLVGAPLLMDRTPDGRPQEVGRVYVYLQ---HPAG 374
Query: 372 ISP---LRLCGSPD-SMFGISLAVLGDLNQDGFPDIAVGAPFDGD---GKVFIYHGSSLG 424
I P L L G + FG SL LGDL+QDG+ D+A+GAPF G+ G VF++ G G
Sbjct: 375 IEPTPTLTLTGHDEFGRFGSSLTPLGDLDQDGYNDVAIGAPFGGETQQGVVFVFPGGPGG 434
Query: 425 VVAKPSQVLEGEAVGIKS---FGYSLSGSLDMDGNQYPDLLVGSLA-DTAVLFRARPILH 480
+ +KPSQVL+ + FG +L G D+DGN YPDL+VGS D AV++R RPI+
Sbjct: 435 LGSKPSQVLQPLWAASHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVDKAVVYRGRPIVS 494
Query: 481 VSHEVSIAPRSIDLEQPNCA--GGHSVCVDLRVCFS----YIAVPSSYSPTVALDYVLDA 534
S ++I P + E+ +C+ G C++L C + ++A ++ + LD+
Sbjct: 495 ASASLTIFPAMFNPEERSCSLEGNPVACINLSFCLNASGKHVADSIGFTVELQLDW---- 550
Query: 535 DTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQL--QENVKDKLRA 592
++ +G V R FL+ + + T+ +++ C + L + +DKL
Sbjct: 551 ---QKQKGGVRRALFLASR----QATLTQTLLIQNGAREDCREMKIYLRNESEFRDKLSP 603
Query: 593 IVVTLSYSLQTPRLRRQAP--GQGLPPVAPILNAHQPSTQRAEIHF-LKQGCGEDKICQS 649
I + L++SL QAP GL P H S R E + CGED IC
Sbjct: 604 IHIALNFSLDP-----QAPVDSHGLRPAL-----HYQSKSRIEDKAQILLDCGEDNICVP 653
Query: 650 NLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADG 709
+LQL +V G L + + L N+
Sbjct: 654 DLQL-------------------EVFGEQNHVYLGDKNALNLTFHAQNVGEG-------- 686
Query: 710 DDAHEAQLLVMLPDSLHYSG-VRALDPAEKPLC--LSNENASHVECELGNPMKRGAQVTF 766
A+EA+L V P YSG VR C + + + C+LGNPMK GA +
Sbjct: 687 -GAYEAELRVTAPPEAEYSGLVRHPGNFSSLSCDYFAVNQSRLLVCDLGNPMKAGASLWG 745
Query: 767 YLILSTSGI--SIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFF 824
L + + + +T + + ++L ++ + VS R V + +++ G++ P+ + F
Sbjct: 746 GLRFTVPHLRDTKKTIQFDFQILSKNLNNSQSDVVSFRLSVEAQAQVTLNGVSKPEAVLF 805
Query: 825 SGVVRGERAM-QSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPM 883
R Q E D+G V + + NQG S ++ L + P + G+ LLY
Sbjct: 806 PVSDWHPRDQPQKEEDLGPAVHHVYELINQGPS--SISQGVLELSCPQAL-EGQQLLYVT 862
Query: 884 QVELEGGQGPGQKGL-CSPR----PNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSW 938
+V GL C+ P L LD + +++ E P +
Sbjct: 863 RVT----------GLNCTTNHPINPKGLELDPEGSLHHQQKREAPSR------------- 899
Query: 939 WPVSSAEKKKNITLDCARGTANCVVFSC---PLYSFDRAAVLHVWGRLWNSTFLEEYSAV 995
SSA I L C A C C PL+ + + L + R+W TFL+
Sbjct: 900 ---SSASSGPQI-LKCPE--AECFRLRCELGPLHQQESQS-LQLHFRVWAKTFLQREHQP 952
Query: 996 KSL--EVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGL 1053
SL E + +A + + I L + V A + GVP W+I+LA+L GL
Sbjct: 953 FSLQCEAVYKA-LKMPYRILPRQLPQKERQVATAVQWTK-AEGSYGVPLWIIILAILFGL 1010
Query: 1054 LVLALLVLLLWKMGFFKRAKHPEATVPQYHAVKIP 1088
L+L LL+ +L+K+GFFKR+ P T + +K P
Sbjct: 1011 LLLGLLIYILYKLGFFKRSL-PYGTAMEKAQLKPP 1044
>gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]
Length = 1002
Score = 297 bits (760), Expect = 4e-80
Identities = 298/1055 (28%), Positives = 485/1055 (45%), Gaps = 138/1055 (13%)
Query: 69 WLLVGAPQA-LALPGQQANRTGGLFACPLSLEETDCYRVDIDQ------GADMQKESKEN 121
+LLVGAP+A PG G + C S C ++ D D E K +
Sbjct: 19 FLLVGAPKANTTQPGIVEG--GQVLKCDWSSTRR-CQPIEFDATGNRDYAKDDPLEFKSH 75
Query: 122 QWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEW 181
QW G SVRS+ KI+ CA Y R + Q R+ +G CF ++D E+
Sbjct: 76 QWFGASVRSKQD--KILACAPLYHWRTEMKQ---EREPVGTCF-------LQDGTKTVEY 123
Query: 182 KFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHL 241
C + + GFCQ G + F+ LL G PG++ W+G + Q + ++
Sbjct: 124 APCRSQDIDADGQGFCQGGFSIDFTKADRVLL-GGPGSFYWQGQL---ISDQVAEIVSKY 179
Query: 242 DDGPYEAGGEKEQDPRLIP-VPANSYFGFSID----SGKGLVRAEELSFVAGAPRANHK- 295
D Y + R + +SY G+S+ +G G+ FV+G PRA
Sbjct: 180 DPNVYSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGID-----DFVSGVPRAARTL 234
Query: 296 GAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEEL 355
G V I + S L +GE++ + FG+S+A D+N D + D+ +GAP F +R +
Sbjct: 235 GMVYIYDGKNMSSLYN---FTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDG 291
Query: 356 G----GAVYVYLNQGGHWAGISPLRLCG-SPDSMFGISLAVLGDLNQDGFPDIAVGAPFD 410
G V V L + +L G + FG ++A LGDL+QDGF DIA+ AP+
Sbjct: 292 KLQEVGQVSVSLQRAS--GDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAAPYG 349
Query: 411 GDGK---VFIYHGSSLGVVAKPSQVLEGEAVGIK---SFGYSLSGSLDMDGNQYPDLLVG 464
G+ K V+I++G S G+ A PSQ+LEG+ SFGYS+ G+ D+D N YPDL+VG
Sbjct: 350 GEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVG 409
Query: 465 SL-ADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSV----CVDLRVCFSYIAVP 519
+ D A+L+RARP++ V+ + + P ++ + C+ + C ++R C A
Sbjct: 410 AFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLK--ADG 467
Query: 520 SSYSPTVALDYVLDADTDR-RLRGQVPRVTFL-SRNLEEPKHQASGTVWLKHQHDRVCGD 577
P L++ ++ D+ + +G + R FL SR+ K+ L + +
Sbjct: 468 KGVLPR-KLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELI--- 523
Query: 578 AMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFL 637
A + + +DKL I + + Y L R A GL PILN P+ + H L
Sbjct: 524 AYLRDESEFRDKLTPITIFMEYRLD---YRTAADTTGL---QPILNQFTPANISRQAHIL 577
Query: 638 KQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTN 697
CGED +C+ L++ D++ + + + D L
Sbjct: 578 LD-CGEDNVCKPKLEV--------SVDSDQKKIYIGDDNPLTLI---------------- 612
Query: 698 LPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPL--CLSNENAS-HVECEL 754
+ Q G+ A+EA+L+V +P + GV + A L EN + V C+L
Sbjct: 613 -----VKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVVCDL 667
Query: 755 GNPMKRGAQVTFYLILSTSGISIETTELEVELLL--ATISEQELHPVSARARVFIELPLS 812
GNPMK G Q+ L S S T ++ +L + + + ++ VS + + + +
Sbjct: 668 GNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLAAVE 727
Query: 813 IAGMAIPQQLFFSGVVRGERA--MQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWP 870
I G++ P +F + E ++E DVG V++ + N G S + A L++ WP
Sbjct: 728 IRGVSSPDHIFLP-IPNWEHKENPETEEDVGPVVQHIYELRNNGPS--SFSKAMLHLQWP 784
Query: 871 HEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQE--P 928
++ N LLY + +++G P ++++ + L+ E+ +
Sbjct: 785 YKY-NNNTLLYILHYDIDG-----------PMNCTSDMEINPLRIKISSLQTTEKNDTVA 832
Query: 929 GERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDR--AAVLHVWGRLWNS 986
G+ + + + + TL C G A C+ C + DR +A+L+V LW
Sbjct: 833 GQGERDHLITKRDLALSEGDIHTLGC--GVAQCLKIVCQVGRLDRGKSAILYVKSLLWTE 890
Query: 987 TFLEEYSAVKSLEVIVRANITV-KSSIKNLMLRDA--STVIPVMVY--LDPMAVVAEGVP 1041
TF+ + + S + A+ V + KNL + D ST++ V + P + VP
Sbjct: 891 TFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPM---PVP 947
Query: 1042 WWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPE 1076
WVI+LAVLAGLL+LA+LV ++++MGFFKR + P+
Sbjct: 948 VWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQ 982
>gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]
Length = 1012
Score = 285 bits (728), Expect = 2e-76
Identities = 311/1118 (27%), Positives = 496/1118 (44%), Gaps = 177/1118 (15%)
Query: 5 RSRDPWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQP 64
R R G G+ L LL+ L AFNLDV G GS FGF+V
Sbjct: 6 RRRLRLGPRGLPLLLSGLLLPL----CRAFNLDVDSPAEYSGPEGSYFGFAVDFFVP-SA 60
Query: 65 RPQSWLLVGAPQA-LALPGQQANRTGGLFACPLSLEETDCYRVDIDQ------GADMQKE 117
+ +LLVGAP+A PG G + C S C ++ D D E
Sbjct: 61 SSRMFLLVGAPKANTTQPGIVEG--GQVLKCDWSSTRR-CQPIEFDATGNRDYAKDDPLE 117
Query: 118 SKENQWLGVSVRSQGPGGKIVTCAHRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELD 177
K +QW G SVRS+ KI+ CA Y R + Q R+ +G CF ++D
Sbjct: 118 FKSHQWFGASVRSKQD--KILACAPLYHWRTEMKQ---EREPVGTCF-------LQDGTK 165
Query: 178 GGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSAD 237
E+ C R +Q + + P+ + + YN + R AQ D
Sbjct: 166 TVEYAPCRSRQLISDQVA----EIVSKYDPNVYSI------KYNNQLATRT---AQAIFD 212
Query: 238 LAHLDDGPYEAGGEKEQDPRLIPVPANSYFGFSID----SGKGLVRAEELSFVAGAPRAN 293
+SY G+S+ +G G+ FV+G PRA
Sbjct: 213 --------------------------DSYLGYSVAVGDFNGDGID-----DFVSGVPRAA 241
Query: 294 HK-GAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQ 352
G V I + S L +GE++ + FG+S+A D+N D + D+ +GAP F +R
Sbjct: 242 RTLGMVYIYDGKNMSSLYN---FTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRG 298
Query: 353 EELG----GAVYVYLNQGGHWAGISPLRLCG-SPDSMFGISLAVLGDLNQDGFPDIAVGA 407
+ G V V L + +L G + FG ++A LGDL+QDGF DIA+ A
Sbjct: 299 SDGKLQEVGQVSVSLQRAS--GDFQTTKLNGFEVFARFGSAIAPLGDLDQDGFNDIAIAA 356
Query: 408 PFDGDGK---VFIYHGSSLGVVAKPSQVLEGEAVGIK---SFGYSLSGSLDMDGNQYPDL 461
P+ G+ K V+I++G S G+ A PSQ+LEG+ SFGYS+ G+ D+D N YPDL
Sbjct: 357 PYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDL 416
Query: 462 LVGSL-ADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSV----CVDLRVCFSYI 516
+VG+ D A+L+RARP++ V+ + + P ++ + C+ + C ++R C
Sbjct: 417 IVGAFGVDRAILYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLK-- 474
Query: 517 AVPSSYSPTVALDYVLDADTDR-RLRGQVPRVTFL-SRNLEEPKHQASGTVWLKHQHDRV 574
A P L++ ++ D+ + +G + R FL SR+ K+ L + +
Sbjct: 475 ADGKGVLPR-KLNFQVELLLDKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELI 533
Query: 575 CGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEI 634
A + + +DKL I + + Y L R A GL PILN P+ +
Sbjct: 534 ---AYLRDESEFRDKLTPITIFMEYRLD---YRTAADTTGL---QPILNQFTPANISRQA 584
Query: 635 HFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELM 694
H L CGED +C+ L++ D++ + + + D L
Sbjct: 585 HILLD-CGEDNVCKPKLEV--------SVDSDQKKIYIGDDNPLTLI------------- 622
Query: 695 VTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPL--CLSNENAS-HVE 751
+ Q G+ A+EA+L+V +P + GV + A L EN + V
Sbjct: 623 --------VKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAFKTENQTRQVV 674
Query: 752 CELGNPMKRGAQVTFYLILSTSGISIETTELEVELLL--ATISEQELHPVSARARVFIEL 809
C+LGNPMK G Q+ L S S T ++ +L + + + ++ VS + + +
Sbjct: 675 CDLGNPMKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSNLFDKVSPVVSHKVDLAVLA 734
Query: 810 PLSIAGMAIPQQLFFSGVVRGERA--MQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNI 867
+ I G++ P +F + E ++E DVG V++ + N G S + A L++
Sbjct: 735 AVEIRGVSSPDHIFLP-IPNWEHKENPETEEDVGPVVQHIYELRNNGPS--SFSKAMLHL 791
Query: 868 MWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQE 927
WP++ N LLY + +++G P ++++ + L+ E+ +
Sbjct: 792 QWPYKY-NNNTLLYILHYDIDG-----------PMNCTSDMEINPLRIKISSLQTTEKND 839
Query: 928 --PGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDR--AAVLHVWGRL 983
G+ + + + + TL C G A C+ C + DR +A+L+V L
Sbjct: 840 TVAGQGERDHLITKRDLALSEGDIHTLGC--GVAQCLKIVCQVGRLDRGKSAILYVKSLL 897
Query: 984 WNSTFLEEYSAVKSLEVIVRANITV-KSSIKNLMLRDA--STVIPVMVY--LDPMAVVAE 1038
W TF+ + + S + A+ V + KNL + D ST++ V + P +
Sbjct: 898 WTETFMNKENQNHSYSLKSSASFNVIEFPYKNLPIEDITNSTLVTTNVTWGIQPAPM--- 954
Query: 1039 GVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPE 1076
VP WVI+LAVLAGLL+LA+LV ++++MGFFKR + P+
Sbjct: 955 PVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQ 992
>gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]
Length = 1039
Score = 282 bits (721), Expect = 1e-75
Identities = 317/1111 (28%), Positives = 492/1111 (44%), Gaps = 175/1111 (15%)
Query: 31 AVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGG 90
A A NLD + G GS FGFS+ H+ R ++VGAP+ L G TGG
Sbjct: 29 AWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVA--IVVGAPRTL---GPSQEETGG 83
Query: 91 LFACPLSLEETDCYRVDIDQ-------GADMQKESKENQWLGVSVRSQGPGGKIVTCA-- 141
+F CP E C + D G+ + K Q LG SV S IV CA
Sbjct: 84 VFLCPWRAEGGQCPSLLFDLRDETRNVGSQTLQTFKARQGLGASVVSWSD--VIVACAPW 141
Query: 142 HRYEARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEG----RPQGHEQFGFC 197
+ ++ ++ +T +G CF+ + R E+ C G R F +
Sbjct: 142 QHWNVLEKTEEAEKTP--VGSCFLAQPESGRR-----AEYSPCRGNTLSRIYVENDFSWD 194
Query: 198 QQGTAAAFSP---DSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGP----YEAGG 250
++ A FS + L+ GAPG Y + G L AQ P +
Sbjct: 195 KRYCEAGFSSVVTQAGELVLGAPGGYYFLG-----LLAQAPVADIFSSYRPGILLWHVSS 249
Query: 251 EKEQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHK-GAVVILRKDSASRL 309
+ P + Y+G+S+ G+ +V GAP + GAV IL DS +
Sbjct: 250 QSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEIL--DSYYQR 307
Query: 310 VPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELG----GAVYVYLN- 364
+ L GE++ S FG+S+AV D+N DG DL+VGAP + E + + G VY++L
Sbjct: 308 LHR--LRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYLFLQP 365
Query: 365 QGGHWAGISPLRLCGSP-DSMFGISLAVLGDLNQDGFPDIAVGAPFDGD---GKVFIYHG 420
+G H G L L G+ FG ++A LGDL++DG+ DIAV AP+ G G+V ++ G
Sbjct: 366 RGPHALGAPSLLLTGTQLYGRFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLG 425
Query: 421 SSLGVVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSL-ADTAVLFRARPIL 479
S G+ ++PSQVL+ +FG+SL G++D+D N YPDL+VG+ A+ ++RA+P++
Sbjct: 426 QSEGLRSRPSQVLDSPFPTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVV 485
Query: 480 HVSHEVSI------APRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLD 533
S ++ + A +S L Q C ++++C A + ++L+ L
Sbjct: 486 KASVQLLVQDSLNPAVKSCVLPQTKTPVS---CFNIQMCVG--ATGHNIPQKLSLNAELQ 540
Query: 534 ADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVW---LKHQHDRVCGDAMFQLQE--NVKD 588
D + +G+ RV L Q +GT L +H +C M L++ + +D
Sbjct: 541 LDRQKPRQGR--RVLLLG-------SQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRD 591
Query: 589 KLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQ 648
KL IV++L+ SL P AP A +L+ ++ I CGED +C
Sbjct: 592 KLSPIVLSLNVSL-PPTEAGMAP-------AVVLHGDTHVQEQTRIVL---DCGEDDVCV 640
Query: 649 SNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQAD 708
LQL +++G P++ V L D A +
Sbjct: 641 PQLQLTA--------------------------SVTGSPLLVGADNVLELQMDAAN---E 671
Query: 709 GDDAHEAQLLVMLPDSLHYSGVRAL---DPAEKPLC-LSNENASHVE-CELGNPMKRGAQ 763
G+ A+EA+L V LP HY +RAL + E+ +C EN + V CELGNPMK+ AQ
Sbjct: 672 GEGAYEAELAVHLPQGAHY--MRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQ 729
Query: 764 VTFYLILSTSGISIETTELEVELLLATISEQE------LHPVSARARVFIELPLSIAGMA 817
+ +++S + + +L + + + Q L V RA +EL G +
Sbjct: 730 IGIAMLVSVGNLEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVEL----RGNS 785
Query: 818 IPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGK 877
P L + GER S G KV++ + N G T+ L+I P + +
Sbjct: 786 FPASLVVA-AEEGEREQNSLDSWGPKVEHTYELHNNGPG--TVNGLHLSIHLPGQ-SQPS 841
Query: 878 WLLYPMQVELEGG-----QGPGQK-----GLCSPRPNILHLDVDSRDRRRRELEPPEQQE 927
LLY + ++ +GG Q P GL P P+ +H RDRR+ L PE ++
Sbjct: 842 DLLYILDIQPQGGLQCFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFL--PEPEQ 899
Query: 928 PGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRA--AVLHVWGRLWN 985
P Q+P + + C +A C V C L R A++ V LW
Sbjct: 900 PSRLQDP---------------VLVSC--DSAPCTVVQCDLQEMARGQRAMVTVLAFLWL 942
Query: 986 STFLEEYSAVKSLEVIVRANI-TVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWV 1044
+ + L+ N+ ++ ++ L L + + A+ +P W
Sbjct: 943 PSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQVWTQLL---RALEERAIPIWW 999
Query: 1045 ILLAVLAGLLVLALLVLLLWKMGFFKRAKHP 1075
+L+ VL GLL+L +LVL +WK+GFFKR + P
Sbjct: 1000 VLVGVLGGLLLLTILVLAMWKVGFFKRNRPP 1030
>gi|67191027 integrin alpha 4 precursor [Homo sapiens]
Length = 1032
Score = 248 bits (634), Expect = 2e-65
Identities = 277/1070 (25%), Positives = 463/1070 (43%), Gaps = 128/1070 (11%)
Query: 34 FNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFA 93
+N+D AL +G +LFG+SV LH R WLLVGAP A L G ++
Sbjct: 34 YNVDTESALLYQGPHNTLFGYSVVLHSHGANR---WLLVGAPTANWLANASVINPGAIYR 90
Query: 94 CPLSLEETD-CYRVDIDQ--GADMQK---ESKENQWLGVSV-RSQGPGGKIVTCAHRYEA 146
C + C ++ + G K E ++NQWLGV++ R G G IVTC HR++
Sbjct: 91 CRIGKNPGQTCEQLQLGSPNGEPCGKTCLEERDNQWLGVTLSRQPGENGSIVTCGHRWKN 150
Query: 147 RQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFCEGRPQGH-EQFGFCQQGTAAAF 205
+ E + G C+ + DL R EL + + E F CQ G ++ +
Sbjct: 151 IFYIKN--ENKLPTGGCYGVPPDL--RTELSKRIAPCYQDYVKKFGENFASCQAGISSFY 206
Query: 206 SPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANS 265
+ D ++ GAPG+ W G+ V ++ Y+A +K+ V S
Sbjct: 207 TKD--LIVMGAPGSSYWTGSLFVY----------NITTNKYKAFLDKQNQ-----VKFGS 249
Query: 266 YFGFSIDSGKGLVRAEELS-FVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGF 324
Y G+S+ G G R++ + V GAP+ G I D + M G++L S F
Sbjct: 250 YLGYSV--GAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNILHEM-KGKKLGSYF 306
Query: 325 GYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQG-GHWAGISPLRLCGSPD- 382
G S+ DLN+DG+ DL+VGAP +EE G V+VY+N G G L GS
Sbjct: 307 GASVCAVDLNADGFSDLLVGAPMQSTIREE--GRVFVYINSGSGAVMNAMETNLVGSDKY 364
Query: 383 -SMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSSLGVVAKPSQVLEGEAV- 438
+ FG S+ LGD++ DGF D+A+GAP + D G ++IY+G + G+ + SQ +EG +
Sbjct: 365 AARFGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGISSTFSQRIEGLQIS 424
Query: 439 -GIKSFGYSLSGSLDMDGNQYPDLLVGSL-ADTAVLFRARPILHVSHEVSIAPRSIDLEQ 496
+ FG S+SG +D D N Y D+ VG+ +D+AVL R RP++ V +S P S++ +
Sbjct: 425 KSLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLS-HPESVNRTK 483
Query: 497 PNCA--GGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNL 554
+C G SVC+DL +CFSY + L Y + D +R+ PR F S
Sbjct: 484 FDCVENGWPSVCIDLTLCFSYKG--KEVPGYIVLFYNMSLDVNRKAESP-PRFYFSSNGT 540
Query: 555 EEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQG 614
+ +G++ + + C ++++V+D L I + +Y L P + + +
Sbjct: 541 SD---VITGSIQVS-SREANCRTHQAFMRKDVRDILTPIQIEAAYHL-GPHVISKRSTEE 595
Query: 615 LPPVAPIL-NAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMD 673
PP+ PIL + + I+F + E+ C ++LQ+ + + +
Sbjct: 596 FPPLQPILQQKKEKDIMKKTINFARFCAHEN--CSADLQVSAKIGFLKPHENK------- 646
Query: 674 VDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRAL 733
A+ + L + + N GDDA+E L V LP L++ ++ L
Sbjct: 647 -----TYLAVGSMKTLMLNVSLFNA----------GDDAYETTLHVKLPVGLYF--IKIL 689
Query: 734 DPAEKPL---CLSNENASHVECELGN-PMKRGAQVTFYLILSTSGISIETTELEVELLLA 789
+ EK + N ++C +G + +++ +L S +S +L + +
Sbjct: 690 ELEEKQINCEVTDNSGVVQLDCSIGYIYVDHLSRIDISFLLDVSSLSRAEEDLSITVHAT 749
Query: 790 TISEQELHPVSARARVFIELP------LSIAGMAIPQQLFFSGVVRGERAMQSERDVGSK 843
+E+E+ + +RV + +P L++ G P + E E + K
Sbjct: 750 CENEEEMDNLK-HSRVTVAIPLKYEVKLTVHGFVNPTSFVYGSNDENE----PETCMVEK 804
Query: 844 VKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRP 903
+ V N G S+ + + IM P+ + L+
Sbjct: 805 MNLTFHVINTGNSMAP--NVSVEIMVPNSFSPQTDKLF---------------------- 840
Query: 904 NILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWP--VSSAEKKKNITLDCARGTANC 961
NIL + + + E ++ E+Q+ +M V K L C + +C
Sbjct: 841 NILDVQTTTGE---CHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKRLLYCIKADPHC 897
Query: 962 VVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDAS 1021
+ F C + V +L + E +L+ +RA + + + + L
Sbjct: 898 LNFLCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGFPEPNPRVIELNKDE 957
Query: 1022 TVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKR 1071
V V++ +I ++L GL+VL L+ ++WK GFFKR
Sbjct: 958 NVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKR 1007
>gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
Length = 1179
Score = 227 bits (578), Expect = 6e-59
Identities = 242/914 (26%), Positives = 399/914 (43%), Gaps = 161/914 (17%)
Query: 198 QQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPR 257
Q G +A +S D +++ GA G Y+W GT ++ +Q + + + K+ +P
Sbjct: 379 QTGFSAHYSQD--WVMLGAVGAYDWNGTVVMQKASQ----IIIPRNTTFNVESTKKNEPL 432
Query: 258 LIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSG 317
SY G++++S + ++ ++AG PR NH G V+I R + + + + LSG
Sbjct: 433 A------SYLGYTVNSATA--SSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQT-LSG 483
Query: 318 ERLTSGFGYSLAVADLNSDGWPD-LIVGAPYFFERQEELGGAVYVY-LNQGG--HWAGIS 373
E++ S FG L D++ D D L+VGAP + ++E G VYVY LNQ + +
Sbjct: 484 EQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLE 543
Query: 374 PLR--LCGSPD--------------SMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKV 415
P++ C S + FG ++A + DLN DGF DI +GAP + D G V
Sbjct: 544 PIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAV 603
Query: 416 FIYHGSSLGVVAKPSQVLE--GEAVGIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLF 473
+IYHGS + + +Q + G+ +K FG S+ G +D++G+ D+ +G L A LF
Sbjct: 604 YIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAA-LF 662
Query: 474 RARPILHVSHEVSIAPRSIDLEQPNC--AGGHSVCVDLRVCFSYIAVPSSYSPTVALDYV 531
+R + V ++ P +++++ NC G +VC++ VCF + + S D +
Sbjct: 663 WSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCINATVCFD-VKLKSKE------DTI 715
Query: 532 LDADTDRRLR----GQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVK 587
+AD R+ Q+ R F +E K Q + TV C F + +
Sbjct: 716 YEADLQYRVTLDSLRQISRSFF--SGTQERKVQRNITV-----RKSECTKHSFYMLDK-H 767
Query: 588 DKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKIC 647
D ++ +TL ++L P P+L+ P++ I F K CG + C
Sbjct: 768 DFQDSVRITLDFNLTDPEN------------GPVLDDSLPNSVHEYIPFAKD-CGNKEKC 814
Query: 648 QSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQA 707
S+L L V+ TE L S + L V N
Sbjct: 815 ISDLSL-------HVATTE----------KDLLIVRSQNDKFNVSLTVKNTK-------- 849
Query: 708 DGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNP-MKRGAQVTF 766
D A+ + +V +L +SG+ A+ +K C SN N + C++G P ++RG VTF
Sbjct: 850 --DSAYNTRTIVHYSPNLVFSGIEAI---QKDSCESNHN---ITCKVGYPFLRRGEMVTF 901
Query: 767 YLILSTSGISIETTEL--EVELLLATISEQELHP-------VSARARVFIELPLSIAGMA 817
++ T+ L V + L+ S+ E P V+ V E+ L A
Sbjct: 902 KILFQ-----FNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSA 956
Query: 818 IPQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGK 877
+ + + S D+G+++ + G + L+I +P+ +NG
Sbjct: 957 SEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSF--PMPELKLSISFPNMTSNGY 1014
Query: 878 WLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMS 937
+LYP G + C RP+I E P G++
Sbjct: 1015 PVLYPT------GLSSSENANC--RPHIF--------------EDPFSINSGKKMT---- 1048
Query: 938 WWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKS 997
S+ K+ LDC T +C L S D + V +V LW TF++ Y + S
Sbjct: 1049 ---TSTDHLKRGTILDC--NTCKFATITCNLTSSDISQV-NVSLILWKPTFIKSYFS--S 1100
Query: 998 LEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLA 1057
L + +R + +++ L + + + + D + VP WVILL+ AGLL+L
Sbjct: 1101 LNLTIRGELRSENASLVLSSSNQKRELAIQISKDGLP---GRVPLWVILLSAFAGLLLLM 1157
Query: 1058 LLVLLLWKMGFFKR 1071
LL+L LWK+GFFKR
Sbjct: 1158 LLILALWKIGFFKR 1171
Score = 57.4 bits (137), Expect = 8e-08
Identities = 38/128 (29%), Positives = 61/128 (47%), Gaps = 11/128 (8%)
Query: 23 LVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPG 82
L+ ++ V+FN+DV ++ G +FG++V +Q + W+L+G+P L G
Sbjct: 18 LLTVVLRCCVSFNVDVKNSMTFSGPVEDMFGYTV---QQYENEEGKWVLIGSP----LVG 70
Query: 83 QQANRTGGLFACPLSL-EETDCYRVDIDQGADMQK--ESKENQWLGVSVRSQGPGGKIVT 139
Q NRTG ++ CP+ E C ++D+ + E KEN G S P G +
Sbjct: 71 QPKNRTGDVYKCPVGRGESLPCVKLDLPVNTSIPNVTEVKENMTFG-STLVTNPNGGFLA 129
Query: 140 CAHRYEAR 147
C Y R
Sbjct: 130 CGPLYAYR 137
>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
Length = 1167
Score = 184 bits (467), Expect = 4e-46
Identities = 229/886 (25%), Positives = 375/886 (42%), Gaps = 135/886 (15%)
Query: 212 LLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGFSI 271
+LFG G Y+W G+ L +G L P E E P L A Y G+S+
Sbjct: 386 ILFGMVGAYDWGGSV---LWLEGGHRLF-----PPRMALEDEFPPALQNHAA--YLGYSV 435
Query: 272 DSGKGLVRAEELSFVAGAPRANHKGAVVI--LRKDSASRLVPEVMLSGERLTSGFGYSLA 329
S L+R F++GAPR H+G V+ L+KD A R+ L GE++ S FG L
Sbjct: 436 SSM--LLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQS--LQGEQIGSYFGSELC 491
Query: 330 VADLNSDGWPD-LIVGAPYFFERQEELGGAVYVYL-NQGGHWAGISPLRLCGSPDSMFGI 387
D + DG D L+V AP F Q + G VYVYL Q L+ D+ FG
Sbjct: 492 PLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQPEPPQDARFGF 551
Query: 388 SLAVLGDLNQDGFPDIAVGAPFDG--DGKVFIYHGSSLGVVAKPSQVLEGEAV--GIKSF 443
++ L DLNQDGF D+AVGAP + G +++YHG+ GV P+Q + ++ + F
Sbjct: 552 AMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAASMPHALSYF 611
Query: 444 GYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNC--AG 501
G S+ G LD+DG+ D+ VG+ A+L +RPI+H++ + + P++I + Q +C G
Sbjct: 612 GRSVDGRLDLDGDDLVDVAVGA-QGAAILLSSRPIVHLTPSLEVTPQAISVVQRDCRRRG 670
Query: 502 GHSVCVDLRVCFSYIA-VPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQ 560
+VC+ +CF + P + + + A D G + L + +
Sbjct: 671 QEAVCLTAALCFQVTSRTPGRWDHQFYMRFT--ASLDEWTAGARAAFDGSGQRLSPRRLR 728
Query: 561 AS-GTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVA 619
S G V + H V + D LR + +T++++L PG
Sbjct: 729 LSVGNVTCEQLHFHVL---------DTSDYLRPVALTVTFALD----NTTKPG------- 768
Query: 620 PILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGT-T 678
P+LN P++ + + F K CG D C ++L L + MD+ G+
Sbjct: 769 PVLNEGSPTSIQKLVPFSKD-CGPDNECVTDLVL---------------QVNMDIRGSRK 812
Query: 679 ALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEK 738
A F + G G ++ + + + ++A+ L ++ +LH + + +
Sbjct: 813 APFVVRG----GRRKVLVSTTLENRK-----ENAYNTSLSLIFSRNLHLASLTPQRESPI 863
Query: 739 PLCLSNENASHVECELGNPM-KRGAQVTFYLILSTSGISIETTELEVELLLATISEQE-- 795
+ + +A C +G+P+ + GA+VTF L S S+ +++ V+L ++ S +
Sbjct: 864 KVECAAPSAHARLCSVGHPVFQTGAKVTFLLEFEFSCSSL-LSQVFVKLTASSDSLERNG 922
Query: 796 -LHPVSARARVFIELPLSIAGMAIPQQLFF--SGVVRGERAMQSERDVGSKVKYEVTVSN 852
L +A+ +I+ P LF S + R E VG +++ T+
Sbjct: 923 TLQDNTAQTSAYIQYE--------PHLLFSSESTLHRYEVHPYGTLPVGPGPEFKTTLRV 974
Query: 853 QGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDS 912
Q + ++ + P G + L QV Q P P +
Sbjct: 975 QNLGCYVVSGLIISALLPAVAHGGNYFLSLSQVITNNASCIVQNLTEPPGPPV------- 1027
Query: 913 RDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSFD 972
PE+ + R S C V C L
Sbjct: 1028 ---------HPEELQHTNRLNGS----------------------NTQCQVVRCHLGQLA 1056
Query: 973 RAAVLHV-WGRLWNSTFLEEYSAVKSLEVIVRANI-TVKSSIKNLMLRDASTVIPVMVYL 1030
+ + V RL ++ F + KSL V+ + T + S+ L L +AS ++ +
Sbjct: 1057 KGTEVSVGLLRLVHNEFFRR-AKFKSLTVVSTFELGTEEGSV--LQLTEASRWSESLLEV 1113
Query: 1031 DPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKHPE 1076
+ + W+++ +VL GLL+LALLV LWK+GFF K PE
Sbjct: 1114 VQTRPIL--ISLWILIGSVLGGLLLLALLVFCLWKLGFFAHKKIPE 1157
Score = 38.1 bits (87), Expect = 0.048
Identities = 32/110 (29%), Positives = 44/110 (40%), Gaps = 9/110 (8%)
Query: 34 FNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFA 93
FNLD G P + FG+SV H Q W+LVGAP G +R G ++
Sbjct: 23 FNLDEHHPRLFPGPPEAEFGYSVLQH---VGGGQRWMLVGAP----WDGPSGDRRGDVYR 75
Query: 94 CPL-SLEETDCYRVDI-DQGADMQKESKENQWLGVSVRSQGPGGKIVTCA 141
CP+ C + + D N LG+S+ G + CA
Sbjct: 76 CPVGGAHNAPCAKGHLGDYQLGNSSHPAVNMHLGMSLLETDGDGGFMACA 125
>gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]
Length = 1170
Score = 159 bits (402), Expect = 1e-38
Identities = 234/920 (25%), Positives = 379/920 (41%), Gaps = 175/920 (19%)
Query: 211 YLLFGAPGTYNWKGTARVELCAQGSADL-AHLDDGPYEAGGEKEQDPRLIPVPANSYFGF 269
+ + GA G +W G G DL A L D + G E L P Y G+
Sbjct: 362 HAVVGAVGAKDWAG---------GFLDLKADLQDDTF-IGNEP-----LTPEVRAGYLGY 406
Query: 270 SIDSGKGLVRAEELSFVA-GAPRANHKGAVVILRKDSASRLVPEVM-LSGERLTSGFGYS 327
++ L ++ S +A GAPR H G V++ ++ +V + G ++ S FG
Sbjct: 407 TVT---WLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGE 463
Query: 328 LAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLC-GSPDSMF 385
L D++ DG +L+ +GAP F+ Q GG V++Y + + +S L+ G P F
Sbjct: 464 LCGVDVDQDGETELLLIGAPLFYGEQR--GGRVFIYQRRQLGFEEVSELQGDPGYPLGRF 521
Query: 386 GISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV--GIKSF 443
G ++ L D+N DG D+AVGAP + G V+I++G G+ +PSQ +EG V GI+ F
Sbjct: 522 GEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWF 581
Query: 444 GYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGH 503
G S+ G D++G+ D+ VG+ + VL +RP++ + +S +P I + + C+
Sbjct: 582 GRSIHGVKDLEGDGLADVAVGAESQMIVL-SSRPVVDMVTLMSFSPAEIPVHEVECSYST 640
Query: 504 S----VCVDLRVCFSYIA-VPSSYSPTVA-LDYVLDADTDR-RLRGQVPRVTF-LSRNLE 555
S V++ +CF + +P VA L Y L D R R RG P L RN+
Sbjct: 641 SNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIA 700
Query: 556 EPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQ----TPRLRRQAP 611
+ C D F V+D + I V+L++SL TPR +R A
Sbjct: 701 VTTSMS-------------CTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQR-AQ 746
Query: 612 GQGLPPVAPILNAHQPS--TQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQP 669
G+ +PP+ +PS ++ EI F K CGEDK C++NL++ F P
Sbjct: 747 GKDIPPIL------RPSLHSETWEIPFEKN-CGEDKKCEANLRV------------SFSP 787
Query: 670 LPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSG 729
TA +LS +EL ++NL +DA+ QL + P L +
Sbjct: 788 ARSRALRLTAFASLS------VELSLSNLE----------EDAYWVQLDLHFPPGLSFRK 831
Query: 730 VRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLA 789
V L K +Q+ +S E E LL
Sbjct: 832 VEML-------------------------KPHSQIP---------VSCEELPEESRLLSR 857
Query: 790 TISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVT 849
+S + P+ AG ++ Q+ F+ +V E + VT
Sbjct: 858 ALSCN------------VSSPIFKAGHSVALQMMFNTLVNSSWGDSVE------LHANVT 899
Query: 850 VSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILH-- 907
+N+ L SA I +LYP+ + ++ + +P+ +H
Sbjct: 900 CNNEDSDLLEDNSATTIIP----------ILYPINILIQDQEDSTLYVSFTPKGPKIHQV 949
Query: 908 -------LDVDSRDRRRRELEP------PEQQEPGERQEPSMSWWPVSSAEKKKNITLDC 954
+ D LE P + P Q PV + D
Sbjct: 950 KHMYQVRIQPSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDA 1009
Query: 955 ARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKN 1014
A +F CP+ F + ++ V G L + E A + +I+ SS
Sbjct: 1010 AEPCLPGALFRCPVV-FRQEILVQVIGTL---ELVGEIEASSMFSLCSSLSISFNSSKHF 1065
Query: 1015 LMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKH 1074
+ +++ V++ +D VV E ++ +L+ + GLL+L L+ ++L+K+GFFKR
Sbjct: 1066 HLYGSNASLAQVVMKVD---VVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLK 1122
Query: 1075 PEATVPQYHAVKIPREDRQQ 1094
+ + IP ED +Q
Sbjct: 1123 EKMEAGRGVPNGIPAEDSEQ 1142
>gi|52485853 integrin, alpha 11 precursor [Homo sapiens]
Length = 1188
Score = 158 bits (399), Expect = 3e-38
Identities = 167/659 (25%), Positives = 287/659 (43%), Gaps = 81/659 (12%)
Query: 164 FVLSQDLAIRDELDG-GEWKFC-EGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYN 221
F ++ + A++D +D G+ F EG + FG T + +L GA G Y+
Sbjct: 330 FNVTDEAALKDIVDALGDRIFSLEGTNKNETSFGLEMSQTGFSSHVVEDGVLLGAVGAYD 389
Query: 222 WKGTARVELCAQGSADL--AHLDDGPYEAGGEKEQDPRLIPVPANSYFGFSIDSGKGLVR 279
W G E A L ++L + P E +Y G+++ S +
Sbjct: 390 WNGAVLKETSAGKVIPLRESYLKEFPEELKNH------------GAYLGYTVTSV--VSS 435
Query: 280 AEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWP 339
+ +VAGAPR NH G V++ + L + G+++ S FG + D++ DG
Sbjct: 436 RQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYFGSEITSVDIDGDGVT 495
Query: 340 D-LIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLCGS-PDSMFGISLAVLGDLNQ 397
D L+VGAP +F E G VYVY + + L+ S ++ FG S+A + DLNQ
Sbjct: 496 DVLLVGAPMYFNEGRE-RGKVYVYELRQNLFVYNGTLKDSHSYQNARFGSSIASVRDLNQ 554
Query: 398 DGFPDIAVGAPFDGD--GKVFIYHGSSLGVVAKPSQVLEGE--AVGIKSFGYSLSGSLDM 453
D + D+ VGAP + + G ++I+HG ++ P Q + A G++ FG S+ G LD+
Sbjct: 555 DSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRITASELATGLQYFGCSIHGQLDL 614
Query: 454 DGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNC--AGGHSVCVDLRV 511
+ + DL VG+L + +L+ +RP++ ++ + P I++ +C +G + C+ +
Sbjct: 615 NEDGLIDLAVGALGNAVILW-SRPVVQINASLHFEPSKINIFHRDCKRSGRDATCLAAFL 673
Query: 512 CFSYI-AVPSSYSPTVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQ 570
CF+ I P + TV + Y D R PR +L+E + + L
Sbjct: 674 CFTPIFLAPHFQTTTVGIRYNATMDE----RRYTPRA-----HLDEGGDRFTNRAVLLSS 724
Query: 571 HDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQ 630
+C F + + D ++ + ++ YSL+ P P+L+ P+T
Sbjct: 725 GQELCERINFHVLDTA-DYVKPVTFSVEYSLED------------PDHGPMLDDGWPTTL 771
Query: 631 RAEIHFLKQGCGEDKICQSNLQL-------VRARFCTRV-----SDTEFQPLPMDVDGTT 678
R + F GC ED+ C +L L +C RV D L D TT
Sbjct: 772 RVSVPFW-NGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFD---TT 827
Query: 679 ALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEK 738
S + + +E + N G++A+ L + +L ++ + + ++
Sbjct: 828 VFIIESTRQRVAVEATLEN----------RGENAYSTVLNISQSANLQFASLIQKEDSDG 877
Query: 739 PL-CLSNENASHVE-CELGNPMKRG-AQVTFYLILSTSGISIETTELEVELLLATISEQ 794
+ C++ E + C + P R A+V F L S SI LE+EL + S +
Sbjct: 878 SIECVNEERRLQKQVCNVSYPFFRAKAKVAFRLDFEFSK-SIFLHHLEIELAAGSDSNE 935
Score = 48.1 bits (113), Expect = 5e-05
Identities = 21/34 (61%), Positives = 28/34 (82%)
Query: 1040 VPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAK 1073
VP W+I+ + L GLL+LALLVL LWK+GFF+ A+
Sbjct: 1140 VPIWIIVGSTLGGLLLLALLVLALWKLGFFRSAR 1173
Score = 36.6 bits (83), Expect = 0.14
Identities = 29/109 (26%), Positives = 50/109 (45%), Gaps = 10/109 (9%)
Query: 34 FNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQALALPGQQANRTGGLFA 93
FN+D G + FG++V H WL+VGAP L G Q +TG ++
Sbjct: 23 FNMDTRKPRVIPGSRTAFFGYTVQQH---DISGNKWLVVGAP--LETNGYQ--KTGDVYK 75
Query: 94 CPLSLEETDCYRVDIDQ-GADMQKESKENQWLGVSVRSQGPGGKIVTCA 141
CP+ +C ++++ + E K+N LG+S+ + + C+
Sbjct: 76 CPVI--HGNCTKLNLGRVTLSNVSERKDNMRLGLSLATNPKDNSFLACS 122
>gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]
Length = 1086
Score = 157 bits (397), Expect = 5e-38
Identities = 233/920 (25%), Positives = 378/920 (41%), Gaps = 176/920 (19%)
Query: 211 YLLFGAPGTYNWKGTARVELCAQGSADL-AHLDDGPYEAGGEKEQDPRLIPVPANSYFGF 269
+ + GA G +W G G DL A L D + G E L P Y G+
Sbjct: 279 HAVVGAVGAKDWAG---------GFLDLKADLQDDTF-IGNEP-----LTPEVRAGYLGY 323
Query: 270 SIDSGKGLVRAEELSFVA-GAPRANHKGAVVILRKDSASRLVPEVM-LSGERLTSGFGYS 327
++ L ++ S +A GAPR H G V++ ++ +V + G ++ S FG
Sbjct: 324 TVT---WLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGE 380
Query: 328 LAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLC-GSPDSMF 385
L D++ DG +L+ +GAP F+ Q GG V++Y + + +S L+ G P F
Sbjct: 381 LCGVDVDQDGETELLLIGAPLFYGEQR--GGRVFIYQRRQLGFEEVSELQGDPGYPLGRF 438
Query: 386 GISLAVLGDLNQDGFPDIAVGAPFDGDGKVFIYHGSSLGVVAKPSQVLEGEAV--GIKSF 443
G ++ L D+N DG D+AVGAP + G V+I++G G+ +PSQ +EG V GI+ F
Sbjct: 439 GEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWF 498
Query: 444 GYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVSIAPRSIDLEQPNCAGGH 503
G S+ G D++G+ D+ VG+ + VL +RP++ + +S +P I + + C+
Sbjct: 499 GRSIHGVKDLEGDGLADVAVGAESQMIVL-SSRPVVDMVTLMSFSPAEIPVHEVECSYST 557
Query: 504 S----VCVDLRVCFSYIA-VPSSYSPTVA-LDYVLDADTDR-RLRGQVPRVTF-LSRNLE 555
S V++ +CF + +P VA L Y L D R R RG P L RN+
Sbjct: 558 SNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIA 617
Query: 556 EPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQ----TPRLRRQAP 611
+ C D F V+D + I V+L++SL TPR +R
Sbjct: 618 VTTSMS-------------CTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRA-- 662
Query: 612 GQGLPPVAPILNAHQPS--TQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRVSDTEFQP 669
G+ +PP+ +PS ++ EI F K CGEDK C++NL++ F P
Sbjct: 663 GKDIPPIL------RPSLHSETWEIPFEKN-CGEDKKCEANLRV------------SFSP 703
Query: 670 LPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLPDSLHYSG 729
TA +LS +EL ++NL +DA+ QL + P L +
Sbjct: 704 ARSRALRLTAFASLS------VELSLSNLE----------EDAYWVQLDLHFPPGLSFRK 747
Query: 730 VRALDPAEKPLCLSNENASHVECELGNPMKRGAQVTFYLILSTSGISIETTELEVELLLA 789
V L K +Q+ +S E E LL
Sbjct: 748 VEML-------------------------KPHSQIP---------VSCEELPEESRLLSR 773
Query: 790 TISEQELHPVSARARVFIELPLSIAGMAIPQQLFFSGVVRGERAMQSERDVGSKVKYEVT 849
+S + P+ AG ++ Q+ F+ +V E + VT
Sbjct: 774 ALSCN------------VSSPIFKAGHSVALQMMFNTLVNSSWGDSVE------LHANVT 815
Query: 850 VSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILH-- 907
+N+ L SA I +LYP+ + ++ + +P+ +H
Sbjct: 816 CNNEDSDLLEDNSATTIIP----------ILYPINILIQDQEDSTLYVSFTPKGPKIHQV 865
Query: 908 -------LDVDSRDRRRRELEP------PEQQEPGERQEPSMSWWPVSSAEKKKNITLDC 954
+ D LE P + P Q PV + D
Sbjct: 866 KHMYQVRIQPSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDA 925
Query: 955 ARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKN 1014
A +F CP+ F + ++ V G L + E A + +I+ SS
Sbjct: 926 AEPCLPGALFRCPVV-FRQEILVQVIGTL---ELVGEIEASSMFSLCSSLSISFNSSKHF 981
Query: 1015 LMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKRAKH 1074
+ +++ V++ +D VV E ++ +L+ + GLL+L L+ ++L+K+GFFKR
Sbjct: 982 HLYGSNASLAQVVMKVD---VVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLK 1038
Query: 1075 PEATVPQYHAVKIPREDRQQ 1094
+ + IP ED +Q
Sbjct: 1039 EKMEAGRGVPNGIPAEDSEQ 1058
>gi|34452173 integrin alpha X precursor [Homo sapiens]
Length = 1163
Score = 146 bits (368), Expect = 1e-34
Identities = 242/915 (26%), Positives = 366/915 (40%), Gaps = 173/915 (18%)
Query: 198 QQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQ-DP 256
Q+G +A F+PD L GA G++ W G A L + P +E D
Sbjct: 353 QEGFSAVFTPDGPVL--GAVGSFTWSG----------GAFLYPPNMSPTFINMSQENVDM 400
Query: 257 RLIPVPANSYFGFSIDSG--KGLVRAEELSFVAGAPRANHKGAVVILRKDSAS-RLVPEV 313
R +SY G+S + KG+ S V GAPR H G VI + S R+ EV
Sbjct: 401 R------DSYLGYSTELALWKGVQ-----SLVLGAPRYQHTGKAVIFTQVSRQWRMKAEV 449
Query: 314 MLSGERLTSGFGYSLAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVY-LNQGGH--W 369
+G ++ S FG SL D++SDG DL+ +GAP+++E+ GG V V L +G W
Sbjct: 450 --TGTQIGSYFGASLCSVDVDSDGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGWRRWW 505
Query: 370 AGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSSLGVVA 427
G P FG +L VLGD+N D D+ +GAP + + G V+++HG LG
Sbjct: 506 CDAVLYGEQGHPWGRFGAALTVLGDVNGDKLTDVVIGAPGEEENRGAVYLFHG-VLGPSI 564
Query: 428 KP--SQVLEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSH 483
P SQ + G + ++ FG +LSG D+ + DL VG+ +L R RP+L V
Sbjct: 565 SPSHSQRIAGSQLSSRLQYFGQALSGGQDLTQDGLVDLAVGARGQ-VLLLRTRPVLWVGV 623
Query: 484 EVSIAPRSIDLEQPNC---AGGHSVCVDLRVCFSYIAVPS-------SYSPTVALDYVLD 533
+ P I C V +C YI S +V LD LD
Sbjct: 624 SMQFIPAEIPRSAFECREQVVSEQTLVQSNICL-YIDKRSKNLLGSRDLQSSVTLDLALD 682
Query: 534 ADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAI 593
RL PR TF +E K+++ V + C + L V+D + I
Sbjct: 683 PG---RLS---PRATF-----QETKNRSLSRVRVLGLKAH-CENFNLLLPSCVEDSVTPI 730
Query: 594 VVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQL 653
+ L+++L P + P+L A A + F ++ CG D ICQ NL
Sbjct: 731 TLRLNFTLV------GKPLLAFRNLRPMLAADAQRYFTASLPF-EKNCGADHICQDNL-- 781
Query: 654 VRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAH 713
+ G +L S + E+MV N DG+D++
Sbjct: 782 ---------------GISFSFPGLKSLLVGSNLE-LNAEVMVWN----------DGEDSY 815
Query: 714 EAQLLVMLPDSLHYSGV---------RALDPAEKPLCLSNENASHVECELGNPMKR-GAQ 763
+ P L Y V R+L + ++ C + + + R GAQ
Sbjct: 816 GTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFRGGAQ 875
Query: 764 VTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLF 823
+TF L+T +S + + LL A +S + P +++ +ELP+ A +
Sbjct: 876 ITF---LATFDVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQLELPVKYAVYTVVSS-- 930
Query: 824 FSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEI-ANGKWLLYP 882
+ +SE + V+N GQ R L +N P E+ W
Sbjct: 931 HEQFTKYLNFSESEEKESHVAMHRYQVNNLGQ--RDL-PVSINFWVPVELNQEAVW---- 983
Query: 883 MQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVS 942
M VE+ Q P + CS ++ PP
Sbjct: 984 MDVEVSHPQNPSLR--CS----------------SEKIAPPASD---------------F 1010
Query: 943 SAEKKKNITLDCARGTANCVVFSC--PLYSFDRAAVLHVWGRL---WNSTFLEEYSAVKS 997
A +KN LDC+ A C+ F C P +S + G L W L+ K
Sbjct: 1011 LAHIQKNPVLDCS--IAGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQ-----KK 1063
Query: 998 LEVIVRANITVKSSI-KNLMLRDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVL 1056
+ V+ A IT +S+ L ++A L+ V P +I+ + + GLL+L
Sbjct: 1064 VSVVSVAEITFDTSVYSQLPGQEAFMRAQTTTVLEKYKV---HNPTPLIVGSSIGGLLLL 1120
Query: 1057 ALLVLLLWKMGFFKR 1071
AL+ +L+K+GFFKR
Sbjct: 1121 ALITAVLYKVGFFKR 1135
Score = 36.6 bits (83), Expect = 0.14
Identities = 34/122 (27%), Positives = 55/122 (45%), Gaps = 22/122 (18%)
Query: 21 SLLVELLFSRAVAFNLDV--MGALRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAPQAL 78
+LL+ + ++ FNLD + A R + FG SV + SW++VGAPQ +
Sbjct: 7 ALLLFTALATSLGFNLDTEELTAFRVDSAG---FGDSVVQYAN------SWVVVGAPQKI 57
Query: 79 ALPGQQANRTGGLFACPLSLEETDCYRVDIDQGADMQKESKENQWLGVSVRSQGPGGKIV 138
AN+TGGL+ C S + + + A N LG+S+ S +++
Sbjct: 58 T----AANQTGGLYQCGYSTGACEPIGLQVPPEA-------VNMSLGLSLASTTSPSQLL 106
Query: 139 TC 140
C
Sbjct: 107 AC 108
>gi|116295258 integrin alpha 2 precursor [Homo sapiens]
Length = 1181
Score = 145 bits (367), Expect = 2e-34
Identities = 159/626 (25%), Positives = 270/626 (43%), Gaps = 88/626 (14%)
Query: 185 EGRPQGHEQFGF--CQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLD 242
EG QG + F Q G +A +S + L+ GA G + W GT V+ + G
Sbjct: 365 EGTVQGGDNFQMEMSQVGFSADYSSQNDILMLGAVGAFGWSGTI-VQKTSHGHLIF---- 419
Query: 243 DGPYEAGGEKEQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILR 302
P +A + QD +SY G+S+ + + E FVAGAPRAN+ G +V+
Sbjct: 420 --PKQAFDQILQDRN-----HSSYLGYSVAA---ISTGESTHFVAGAPRANYTGQIVLYS 469
Query: 303 KDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPD-LIVGAPYFFERQEELGGAVYV 361
+ + G+++ S FG L D++ D D L+VGAP + ++ G VY+
Sbjct: 470 VNENGNITVIQAHRGDQIGSYFGSVLCSVDVDKDTITDVLLVGAPMYMSDLKKEEGRVYL 529
Query: 362 YLNQGG----HWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFD--GDGKV 415
+ + G H P G ++ FG ++A L D+N DGF D+ VG+P + G V
Sbjct: 530 FTIKEGILGQHQFLEGPE---GIENTRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAV 586
Query: 416 FIYHGSSLGVVAKPSQVLEGEAVGIKS----FGYSLSGSLDMDGNQYPDLLVGSLADTAV 471
+IY+G + K SQ + G +S FG SL G D++G+ D+ +G+
Sbjct: 587 YIYNGHQGTIRTKYSQKILGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQ 646
Query: 472 LFRARPILHVSHEVSIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSPTVALDYV 531
L+ ++ I V+ E S P I L N + L++CFS P+ + VA+ Y
Sbjct: 647 LW-SQSIADVAIEASFTPEKITLVNKNAQ------IILKLCFSAKFRPTKQNNQVAIVYN 699
Query: 532 LDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLR 591
+ D D G RVT SR L + ++ + + C + + +QE D +
Sbjct: 700 ITLDAD----GFSSRVT--SRGLFKENNERCLQKNMVVNQAQSCPEHIIYIQE-PSDVVN 752
Query: 592 AIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNL 651
++ + + SL+ P +P L A+ + + I F K CGED +C S+L
Sbjct: 753 SLDLRVDISLEN------------PGTSPALEAYSETAKVFSIPFHKD-CGEDGLCISDL 799
Query: 652 QL-VRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGD 710
L VR ++ + QP + F+++ + +
Sbjct: 800 VLDVR-----QIPAAQEQPFIVSNQNKRLTFSVT--------------------LKNKRE 834
Query: 711 DAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNP-MKRGAQVTFYLI 769
A+ ++V ++L ++ + C + V C++G P +KR QVTF +
Sbjct: 835 SAYNTGIVVDFSENLFFASFSLPVDGTEVTCQVAASQKSVACDVGYPALKREQQVTFTI- 893
Query: 770 LSTSGISIETTELEVELLLATISEQE 795
+++ + + L +SE +
Sbjct: 894 --NFDFNLQNLQNQASLSFQALSESQ 917
Score = 53.1 bits (126), Expect = 1e-06
Identities = 38/117 (32%), Positives = 63/117 (53%), Gaps = 10/117 (8%)
Query: 958 TANCVVFSCPLYSFDRAA--VLHVWGRLWNSTFLEEYSAVKSLEVIVRANITVKSSIKNL 1015
TA+C +C L ++V R+WN TF S +++++ A I + +
Sbjct: 1052 TASCSNVTCWLKDVHMKGEYFVNVTTRIWNGTFAS--STFQTVQLTAAAEINTYNP-EIY 1108
Query: 1016 MLRDASTVIPVMVYL-DPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKR 1071
++ D + IP+M+ D A V GV I+ +++AG+L+L LV +LWK+GFFKR
Sbjct: 1109 VIEDNTVTIPLMIMKPDEKAEVPTGV----IIGSIIAGILLLLALVAILWKLGFFKR 1161
>gi|148728188 integrin, alpha E precursor [Homo sapiens]
Length = 1179
Score = 145 bits (365), Expect = 3e-34
Identities = 137/475 (28%), Positives = 215/475 (45%), Gaps = 80/475 (16%)
Query: 208 DSHYLLFGAPGTYNWKGTA--------RVELCAQGSADLAHLDDGPYEAGGEKEQDPRLI 259
D +L GA G ++W G A R Q +A A + Y
Sbjct: 412 DERQVLLGAVGAFDWSGGALLYDTRSRRGRFLNQTAAAAADAEAAQY------------- 458
Query: 260 PVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVMLSGER 319
SY G+++ L + LS++AGAPR H GAV L+K+ V L GE+
Sbjct: 459 -----SYLGYAVAV---LHKTCSLSYIAGAPRYKHHGAVFELQKEGREASFLPV-LEGEQ 509
Query: 320 LTSGFGYSLAVADLNSDGWPD-LIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRLC 378
+ S FG L D++ DG D L+V AP++ EE G VYVY + L
Sbjct: 510 MGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEE--GRVYVYRLSEQDGSFSLARILS 567
Query: 379 GSP---DSMFGISLAVLGDLNQDGFPDIAVGAPFDG--------DGKVFIYHGSSLGVVA 427
G P ++ FG ++A +GDL+QD D+A+GAP +G G V+IY+G G+ A
Sbjct: 568 GHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSA 627
Query: 428 KPSQVLEGEAV--GIKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEV 485
PSQ + V G++ FG S++G D+ G+ D+ VG+L AV+FR+RP++ + +
Sbjct: 628 SPSQRIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLGQ-AVVFRSRPVVRLKVSM 686
Query: 486 SIAPRSIDLEQPNCAGGHSVCVDLRVCFSYIAVPSSYSP---TVALDYVLDADTDR-RLR 541
+ P ++ + G + V++R+CF +V ++ L++ LD D + R R
Sbjct: 687 AFTPSALPI-------GFNGVVNVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRR 739
Query: 542 GQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQEN---VKDKLRAIVVTLS 598
Q V L E +SG+ ++C D + E +D V +S
Sbjct: 740 LQCSDVRSCLGCLRE---WSSGS--------QLCEDLLLMPTEGELCEEDCFSNASVKVS 788
Query: 599 YSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQL 653
Y LQTP + P PIL+ + ++ + ++ C C + LQL
Sbjct: 789 YQLQTPEGQTDHP-------QPILDRYTEPFAIFQLPY-EKACKNKLFCVAELQL 835
Score = 33.5 bits (75), Expect = 1.2
Identities = 30/92 (32%), Positives = 43/92 (46%), Gaps = 11/92 (11%)
Query: 17 YLFGSLLVELLFSRAVAFNLDVMGA-LRKEGEPGSLFGFSVALHRQLQPRPQSWLLVGAP 75
+LF +LL + AFN+DV L +G G+ F S LH+ Q+WLLV +P
Sbjct: 2 WLFHTLLCIASLALLAAFNVDVARPWLTPKG--GAPFVLSSLLHQDPSTN-QTWLLVTSP 58
Query: 76 QALALPGQQANRTGGLFACPLSLEETDCYRVD 107
+ PG L C L +E C+ V+
Sbjct: 59 RTKRTPGP-------LHRCSLVQDEILCHPVE 83
Score = 32.0 bits (71), Expect = 3.4
Identities = 13/28 (46%), Positives = 22/28 (78%)
Query: 1044 VILLAVLAGLLVLALLVLLLWKMGFFKR 1071
+I+ + GLLVL +++++L+K GFFKR
Sbjct: 1127 IIIKGSVGGLLVLIVILVILFKCGFFKR 1154
>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
Length = 1153
Score = 132 bits (331), Expect = 2e-30
Identities = 203/908 (22%), Positives = 354/908 (38%), Gaps = 157/908 (17%)
Query: 198 QQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSA--DLAHLDDGPYEAGGEKEQD 255
Q+G +AA + S+ L G+Y+W G + + S ++ +D +A
Sbjct: 352 QEGFSAAIT--SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDA------- 402
Query: 256 PRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVML 315
Y G++ ++R S V GAPR H G V + R+++ +
Sbjct: 403 ----------YLGYAAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGM-WESNANV 448
Query: 316 SGERLTSGFGYSLAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVY---LNQGGHWAG 371
G ++ + FG SL D++S+G DL+ +GAP+++E+ GG V V Q W
Sbjct: 449 KGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGQRARWQC 506
Query: 372 ISPLR-LCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSS-LGVVA 427
+ L G P FG +L VLGD+N D D+A+GAP + D G V+++HG+S G+
Sbjct: 507 DAVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISP 566
Query: 428 KPSQVLEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEV 485
SQ + G + ++ FG SLSG D+ + DL VG+ +L R++P+L V +
Sbjct: 567 SHSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGH-VLLLRSQPVLRVKAIM 625
Query: 486 SIAPRSIDLEQPNC---------AGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADT 536
PR + C AG VC+ ++ V D LD+
Sbjct: 626 EFNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSG- 684
Query: 537 DRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVT 596
R V ++N + Q G + C QL ++D + IV+
Sbjct: 685 ----RPHSRAVFNETKNSTRRQTQVLGLT-------QTCETLKLQLPNCIEDPVSPIVLR 733
Query: 597 LSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRA 656
L++SL P + P+L A + ++ CG D ICQ +L +
Sbjct: 734 LNFSLV------GTPLSAFGNLRPVL-AEDAQRLFTALFPFEKNCGNDNICQDDLSIT-- 784
Query: 657 RFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQ 716
F + +D + G + + V N DG+D++ Q
Sbjct: 785 ----------FSFMSLD------CLVVGGPREFNVTVTVRN----------DGEDSYRTQ 818
Query: 717 LLVMLPDSLHYSGVRAL--DPAEKPLCLSNENASHVE---------CELGNPM-KRGAQV 764
+ P L Y V L +++ L+ E+AS E C + +P+ ++V
Sbjct: 819 VTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEV 878
Query: 765 TFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFF 824
TF + + +L LL A ++ + P + + +ELP+ A+ +
Sbjct: 879 TFNITFDVDSKASLGNKL---LLKANVTSENNMPRTNKTEFQLELPVK---YAVYMVVTS 932
Query: 825 SGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQ 884
GV + + ++++ VSN GQ + F L P++
Sbjct: 933 HGVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPISLVF---------------LVPVR 977
Query: 885 VELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSA 944
+ + + RP + + S +E P A
Sbjct: 978 L---------NQTVIWDRPQVTFSENLSSTCHTKERLPSHSD---------------FLA 1013
Query: 945 EKKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRA 1004
E +K ++C+ + P + + G L +++ ++ L ++ A
Sbjct: 1014 ELRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIK--TSHNHLLIVSTA 1071
Query: 1005 NITVKSSIKNLMLRDASTV-IPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLL 1063
I S+ L+ + V ++P V P +I+ + + GLL+LAL+ L
Sbjct: 1072 EILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPN---PLPLIVGSSVGGLLLLALITAAL 1128
Query: 1064 WKMGFFKR 1071
+K+GFFKR
Sbjct: 1129 YKLGFFKR 1136
>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
Length = 1152
Score = 131 bits (329), Expect = 4e-30
Identities = 204/907 (22%), Positives = 356/907 (39%), Gaps = 156/907 (17%)
Query: 198 QQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSA--DLAHLDDGPYEAGGEKEQD 255
Q+G +AA + S+ L G+Y+W G + + S ++ +D +A
Sbjct: 352 QEGFSAAIT--SNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDA------- 402
Query: 256 PRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSASRLVPEVML 315
Y G++ ++R S V GAPR H G V + R+++ +
Sbjct: 403 ----------YLGYAAAI---ILRNRVQSLVLGAPRYQHIGLVAMFRQNTGM-WESNANV 448
Query: 316 SGERLTSGFGYSLAVADLNSDGWPDLI-VGAPYFFERQEELGGAVYVY-LNQG-GHWAGI 372
G ++ + FG SL D++S+G DL+ +GAP+++E+ GG V V L +G W
Sbjct: 449 KGTQIGAYFGASLCSVDVDSNGSTDLVLIGAPHYYEQTR--GGQVSVCPLPRGRARWQCD 506
Query: 373 SPLR-LCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSS-LGVVAK 428
+ L G P FG +L VLGD+N D D+A+GAP + D G V+++HG+S G+
Sbjct: 507 AVLYGEQGQPWGRFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPS 566
Query: 429 PSQVLEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGSLADTAVLFRARPILHVSHEVS 486
SQ + G + ++ FG SLSG D+ + DL VG+ +L R++P+L V +
Sbjct: 567 HSQRIAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGH-VLLLRSQPVLRVKAIME 625
Query: 487 IAPRSIDLEQPNC---------AGGHSVCVDLRVCFSYIAVPSSYSPTVALDYVLDADTD 537
PR + C AG VC+ ++ V D LD+
Sbjct: 626 FNPREVARNVFECNDQVVKGKEAGEVRVCLHVQKSTRDRLREGQIQSVVTYDLALDSG-- 683
Query: 538 RRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTL 597
R V ++N + Q G + C QL ++D + IV+ L
Sbjct: 684 ---RPHSRAVFNETKNSTRRQTQVLGLT-------QTCETLKLQLPNCIEDPVSPIVLRL 733
Query: 598 SYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRAR 657
++SL P + P+L A + ++ CG D ICQ +L +
Sbjct: 734 NFSLV------GTPLSAFGNLRPVL-AEDAQRLFTALFPFEKNCGNDNICQDDLSIT--- 783
Query: 658 FCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQL 717
F + +D + G + + V N DG+D++ Q+
Sbjct: 784 ---------FSFMSLD------CLVVGGPREFNVTVTVRN----------DGEDSYRTQV 818
Query: 718 LVMLPDSLHYSGVRAL--DPAEKPLCLSNENASHVE---------CELGNPM-KRGAQVT 765
P L Y V L +++ L+ E+AS E C + +P+ ++VT
Sbjct: 819 TFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCSINHPIFPENSEVT 878
Query: 766 FYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELPLSIAGMAIPQQLFFS 825
F + + +L LL A ++ + P + + +ELP+ A+ +
Sbjct: 879 FNITFDVDSKASLGNKL---LLKANVTSENNMPRTNKTEFQLELPVK---YAVYMVVTSH 932
Query: 826 GVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQV 885
GV + + ++++ VSN GQ + F L P+++
Sbjct: 933 GVSTKYLNFTASENTSRVMQHQYQVSNLGQRSLPISLVF---------------LVPVRL 977
Query: 886 ELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAE 945
+ + RP + + S +E P AE
Sbjct: 978 ---------NQTVIWDRPQVTFSENLSSTCHTKERLPSHSD---------------FLAE 1013
Query: 946 KKKNITLDCARGTANCVVFSCPLYSFDRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRAN 1005
+K ++C+ + P + + G L +++ ++ L ++ A
Sbjct: 1014 LRKAPVVNCSIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIK--TSHNHLLIVSTAE 1071
Query: 1006 ITVKSSIKNLMLRDASTV-IPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLW 1064
I S+ L+ + V ++P V P +I+ + + GLL+LAL+ L+
Sbjct: 1072 ILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPN---PLPLIVGSSVGGLLLLALITAALY 1128
Query: 1065 KMGFFKR 1071
K+GFFKR
Sbjct: 1129 KLGFFKR 1135
>gi|62548866 integrin, alpha D precursor [Homo sapiens]
Length = 1161
Score = 124 bits (310), Expect = 7e-28
Identities = 223/933 (23%), Positives = 376/933 (40%), Gaps = 187/933 (20%)
Query: 185 EGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDG 244
+ R Q Q+G + A + D +L GA G+++W G A L +
Sbjct: 339 QSRASSSFQHEMSQEGFSTALTMDGLFL--GAVGSFSWSG----------GAFLYPPNMS 386
Query: 245 PYEAGGEKEQ-DPRLIPVPANSYFGFSIDSG--KGLVRAEELSFVAGAPRANHKGAVVIL 301
P +E D R +SY G+S + KG+ + V GAPR H G VI
Sbjct: 387 PTFINMSQENVDMR------DSYLGYSTELALWKGVQ-----NLVLGAPRYQHTGKAVIF 435
Query: 302 RKDSAS-RLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLI-VGAPYFFERQEELGGAV 359
+ S R EV +G ++ S FG SL D++SDG DLI +GAP+++E+ GG V
Sbjct: 436 TQVSRQWRKKAEV--TGTQIGSYFGASLCSVDVDSDGSTDLILIGAPHYYEQTR--GGQV 491
Query: 360 YVYLNQGGH--WAGISPLR-LCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GK 414
V G W + LR G P FG +L VLGD+N+D D+A+GAP + + G
Sbjct: 492 SVCPLPRGRVQWQCDAVLRGEQGHPWGRFGAALTVLGDVNEDKLIDVAIGAPGEQENRGA 551
Query: 415 VFIYHGSS-LGVVAKPSQVLEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGSLADTAV 471
V+++HG+S G+ SQ + + ++ FG +LSG D+ + DL VG+ +
Sbjct: 552 VYLFHGASESGISPSHSQRIASSQLSPRLQYFGQALSGGQDLTQDGLMDLAVGARGQ-VL 610
Query: 472 LFRARPILHVSHEVSIAPRSIDLEQPNC---------AGGHSVCVDLRVCFSYIAVPSSY 522
L R+ P+L V + +P + C AG +VC+ ++ S +
Sbjct: 611 LLRSLPVLKVGVAMRFSPVEVAKAVYRCWEEKPSALEAGDATVCLTIQK--SSLDQLGDI 668
Query: 523 SPTVALDYVLDAD--TDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMF 580
+V D LD T R + + T R T+ L C
Sbjct: 669 QSSVRFDLALDPGRLTSRAIFNETKNPTLTRRK----------TLGLGIH----CETLKL 714
Query: 581 QLQENVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPILNAHQPSTQRAEIHFLKQG 640
L + V+D + I++ L++SL +R P + P+L A + F ++
Sbjct: 715 LLPDCVEDVVSPIILHLNFSL----VREPIPSP--QNLRPVLAVGSQDLFTASLPF-EKN 767
Query: 641 CGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPS 700
CG+D +C+ +L + + + L L+ + L ++VT +
Sbjct: 768 CGQDGLCEGDLGVTLS--------------------FSGLQTLTVGSSLELNVIVTVWNA 807
Query: 701 DPAQPQADGDDAHEAQLLVMLPDSLHYSGV---------RALDPAEKPLCLSNENASHVE 751
G+D++ + + P L + V AL A + + +E
Sbjct: 808 --------GEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRSSR 859
Query: 752 CELGNPM-KRGAQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFIELP 810
C + +P+ G+ TF + T +S + T + L+ A+ S + S++A +ELP
Sbjct: 860 CSVNHPIFHEGSNGTF---IVTFDVSYKATLGDRMLMRASASSENNKASSSKATFQLELP 916
Query: 811 LSIAGMAI-----PQQLFFSGVVRGERAMQSERDVGSKVKYEVTVSNQGQSLRTLGSAFL 865
+ A + +F+ E+ M+ + ++ V+N Q + F
Sbjct: 917 VKYAVYTMISRQEESTKYFNFATSDEKKMK-------EAEHRYRVNNLSQRDLAISINF- 968
Query: 866 NIMWPHEIANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRRRELEPPEQ 925
W + NG + DV +E P Q
Sbjct: 969 ---WVPVLLNG----------------------------VAVWDV--------VMEAPSQ 989
Query: 926 QEP--GERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSC--PLYSFDRAAVLHVWG 981
P ER+ P S + + ++ LDC+ A+C+ F C P +S + G
Sbjct: 990 SLPCVSERKPPQHSDF---LTQISRSPMLDCS--IADCLQFRCDVPSFSVQEELDFTLKG 1044
Query: 982 RL---WNSTFLEEYSAVKSLEVIVRANITVKSSIKNLMLRDASTVIPVMVYLDPMAVVAE 1038
L W L+ K + V+ A IT +S+ + + + + M + V
Sbjct: 1045 NLSFGWVRETLQ-----KKVLVVSVAEITFDTSVYSQLPGQEAFMRAQMEMVLEEDEVYN 1099
Query: 1039 GVPWWVILLAVLAGLLVLALLVLLLWKMGFFKR 1071
+P +I+ + + LL+LAL+ L+K+GFFKR
Sbjct: 1100 AIP--IIMGSSVGALLLLALITATLYKLGFFKR 1130
>gi|29171717 glycosylphosphatidylinositol specific phospholipase D1
isoform 1 precursor [Homo sapiens]
Length = 840
Score = 71.2 bits (173), Expect = 5e-12
Identities = 54/158 (34%), Positives = 79/158 (50%), Gaps = 22/158 (13%)
Query: 325 GYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGISPLRL------- 377
G+++ ADLN DG DL+VGAP + G VY+ G+ G+ P+ L
Sbjct: 382 GWAMTSADLNQDGHGDLVVGAPGYSRPGHIHIGRVYLIY---GNDLGLPPVDLDLDKEAH 438
Query: 378 ----CGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD------GKVFIYHGSSLGVVA 427
P FG +LAVL D N DG PD+AVGAP G G V++Y GS G ++
Sbjct: 439 RILEGFQPSGRFGSALAVL-DFNVDGVPDLAVGAPSVGSEQLTYKGAVYVYFGSKQGGMS 497
Query: 428 KPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGS 465
+ + G++L + D++G+ PDL++GS
Sbjct: 498 SSPNITISCQDIYCNLGWTLLAA-DVNGDSEPDLVIGS 534
Score = 65.1 bits (157), Expect = 4e-10
Identities = 59/164 (35%), Positives = 73/164 (44%), Gaps = 16/164 (9%)
Query: 314 MLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQGGHWAGIS 373
+L G + + FG +LAV D N DG PDL VGAP Q GAVYVY S
Sbjct: 440 ILEGFQPSGRFGSALAVLDFNVDGVPDLAVGAPSVGSEQLTYKGAVYVYFGSKQGGMSSS 499
Query: 374 PLRLCGSPDSMFGISLAVL-GDLNQDGFPDIAVGAPF-DGDGK-----VFIYHGSSLG-- 424
P D + +L D+N D PD+ +G+PF G GK Y G SL
Sbjct: 500 PNITISCQDIYCNLGWTLLAADVNGDSEPDLVIGSPFAPGGGKQKGIVAAFYSGPSLSDK 559
Query: 425 ---VVAKPSQVLEGEAVGIKSFGYSLSGSLDMDGNQYPDLLVGS 465
V + + GE FGYSL G + +D LLVGS
Sbjct: 560 EKLNVEAANWTVRGEE-DFSWFGYSLHG-VTVDNRTL--LLVGS 599
Score = 41.6 bits (96), Expect = 0.004
Identities = 19/62 (30%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
Query: 288 GAPRANHKGAVVIL--RKDSASRLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGA 345
G+ + +KGAV + K P + +S + + G++L AD+N D PDL++G+
Sbjct: 475 GSEQLTYKGAVYVYFGSKQGGMSSSPNITISCQDIYCNLGWTLLAADVNGDSEPDLVIGS 534
Query: 346 PY 347
P+
Sbjct: 535 PF 536
Score = 31.2 bits (69), Expect = 5.9
Identities = 47/186 (25%), Positives = 74/186 (39%), Gaps = 45/186 (24%)
Query: 189 QGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEA 248
+G E F + + LL G+P WK +R+ L H+ D
Sbjct: 572 RGEEDFSWFGYSLHGVTVDNRTLLLVGSP---TWKNASRL-------GHLLHIRD----- 616
Query: 249 GGEKEQDPRL---IPVPANSYF-----------GFSIDSGKGLVRAE-ELSFVAGAPRAN 293
EK+ R+ P S+F G S+ SG L+ + + GAP +
Sbjct: 617 --EKKSLGRVYGYFPPNGQSWFTISGDKAMGKLGTSLSSGHVLMNGTLKQVLLVGAPTYD 674
Query: 294 HKGAV----VILRKDSASRLV-------PEVM--LSGERLTSGFGYSLAVADLNSDGWPD 340
V V L + A+R+ P ++ SG+R S FG L ++DL+ DG +
Sbjct: 675 DVSKVAFLTVTLHQGGATRMYALTSDAQPLLLSTFSGDRRFSRFGGVLHLSDLDDDGLDE 734
Query: 341 LIVGAP 346
+I+ AP
Sbjct: 735 IIMAAP 740
>gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo
sapiens]
Length = 462
Score = 46.6 bits (109), Expect = 1e-04
Identities = 116/469 (24%), Positives = 177/469 (37%), Gaps = 86/469 (18%)
Query: 638 KQGCGEDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTN 697
++ CG D ICQ NL + G +L S + E+MV N
Sbjct: 17 EKNCGADHICQDNLGI-----------------SFSFPGLKSLLVGSNLE-LNAEVMVWN 58
Query: 698 LPSDPAQPQADGDDAHEAQLLVMLPDSLHYSGV---------RALDPAEKPLCLSNENAS 748
DG+D++ + P L Y V R+L + ++
Sbjct: 59 ----------DGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTW 108
Query: 749 HVECELGNPMKRG-AQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFI 807
C + + + RG AQ+TF L+T +S + + LL A +S + P +++ +
Sbjct: 109 STSCRINHLIFRGGAQITF---LATFDVSPKAVLGDRLLLTANVSSENNTPRTSKTTFQL 165
Query: 808 ELPLSIAGMAI-------PQQLFFSGVVRGER--AMQSERDVGSKVKYEVTVSNQGQSLR 858
ELP+ A + + L FS E AM + G V+N GQ R
Sbjct: 166 ELPVKYAVYTVVSSHEQFTKYLNFSESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQ--R 223
Query: 859 TLGSAFLNIMWPHEI-ANGKWLLYPMQVELEGGQGPGQKGLCSPRPNILHLDVDSRDRRR 917
L + +N P E+ W M VE+ Q P C + +DS
Sbjct: 224 DLPVS-INFWVPVELNQEAVW----MDVEVSHPQVPKD---CMWLLHECPFYLDSLCPMW 275
Query: 918 RELEPPEQ-------QEPGERQEPSMSWWPVSS--AEKKKNITLDCARGTANCVVFSC-- 966
P E Q P R P S A +KN LDC+ A C+ F C
Sbjct: 276 VPDVPAETLVLCIFPQNPSLRCSSEKIAPPASDFLAHIQKNPVLDCS--IAGCLRFRCDV 333
Query: 967 PLYSFDRAAVLHVWGRL---WNSTFLEEYSAVKSLEVIVRANITVKSSI-KNLMLRDAST 1022
P +S + G L W L+ K + V+ A IT +S+ L ++A
Sbjct: 334 PSFSVQEELDFTLKGNLSFGWVRQILQ-----KKVSVVSVAEITFDTSVYSQLPGQEAFM 388
Query: 1023 VIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLLLWKMGFFKR 1071
L+ V P +I+ + + GLL+LAL+ +L+K+GFFKR
Sbjct: 389 RAQTTTVLEKYKVHN---PTPLIVGSSIGGLLLLALITAVLYKVGFFKR 434
>gi|169214874 PREDICTED: hypothetical protein [Homo sapiens]
Length = 583
Score = 33.5 bits (75), Expect = 1.2
Identities = 30/98 (30%), Positives = 40/98 (40%), Gaps = 30/98 (30%)
Query: 177 DGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTY-------------NWK 223
DGG+W +GHEQ AA ++ HYL GAPG +
Sbjct: 72 DGGDW-------EGHEQ-------DAAQYAAQGHYLARGAPGDHVAIAHRRHGDDSPPVA 117
Query: 224 GTARVELCAQGSADLAHLDDGPYEAGG---EKEQDPRL 258
G EL A G L ++ G E G E++Q+P L
Sbjct: 118 GRDAGELGAVGHLVLDDVEQGREEGDGHAEEEQQEPEL 155
>gi|169215109 PREDICTED: hypothetical protein [Homo sapiens]
Length = 583
Score = 33.5 bits (75), Expect = 1.2
Identities = 30/98 (30%), Positives = 40/98 (40%), Gaps = 30/98 (30%)
Query: 177 DGGEWKFCEGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTY-------------NWK 223
DGG+W +GHEQ AA ++ HYL GAPG +
Sbjct: 72 DGGDW-------EGHEQ-------DAAQYAAQGHYLARGAPGDHVAIAHRRHGDDSPPVA 117
Query: 224 GTARVELCAQGSADLAHLDDGPYEAGG---EKEQDPRL 258
G EL A G L ++ G E G E++Q+P L
Sbjct: 118 GRDAGELGAVGHLVLDDVEQGREEGDGHAEEEQQEPEL 155
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,854,766
Number of Sequences: 37866
Number of extensions: 2393400
Number of successful extensions: 6173
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 5776
Number of HSP's gapped (non-prelim): 101
length of query: 1141
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1028
effective length of database: 13,968,660
effective search space: 14359782480
effective search space used: 14359782480
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.