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Search of human proteins with 222136632
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|222136632 NFKB inhibitor interacting Ras-like 2 isoform c
[Homo sapiens]
(97 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222136632 NFKB inhibitor interacting Ras-like 2 isoform c [Ho... 195 7e-51
gi|222136630 NFKB inhibitor interacting Ras-like 2 isoform b [Ho... 115 1e-26
gi|222136628 NFKB inhibitor interacting Ras-like 2 isoform a [Ho... 115 1e-26
gi|19072794 NFKB inhibitor interacting Ras-like 2 isoform a [Hom... 115 1e-26
gi|47777758 NFKB inhibitor interacting Ras-like 2 isoform a [Hom... 115 1e-26
gi|9966809 kappa B-ras 1 [Homo sapiens] 91 2e-19
gi|55953120 RAS-related on chromosome 22 isoform b [Homo sapiens] 33 0.064
gi|5454030 RAS-related on chromosome 22 isoform a [Homo sapiens] 33 0.064
gi|4885581 Rho family GTPase 2 [Homo sapiens] 31 0.24
gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens] 29 0.71
gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens] 29 0.92
gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens] 29 0.92
gi|11034843 ras homolog gene family, member U [Homo sapiens] 28 1.2
gi|7657033 5',3'-nucleotidase, cytosolic [Homo sapiens] 28 1.2
gi|96975135 RAB24 gene product [Homo sapiens] 28 1.6
gi|72534833 RAB24 gene product [Homo sapiens] 28 1.6
gi|24415404 MDN1, midasin homolog [Homo sapiens] 28 1.6
gi|4885069 ras homolog gene family, member E [Homo sapiens] 28 2.1
gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [H... 27 2.7
gi|4757772 DIRAS family, GTP-binding RAS-like 3 [Homo sapiens] 27 2.7
gi|28376635 RAB37, member RAS oncogene family isoform 3 [Homo sa... 27 2.7
gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapi... 27 2.7
gi|223671872 inhibitor of kappa light polypeptide gene enhancer ... 27 3.5
gi|74096429 RAB41, member RAS oncogene family [Homo sapiens] 27 4.6
gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens] 26 6.0
gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens] 26 6.0
gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens] 26 6.0
gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens] 26 6.0
gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens] 26 6.0
gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens] 26 6.0
>gi|222136632 NFKB inhibitor interacting Ras-like 2 isoform c
[Homo sapiens]
Length = 97
Score = 195 bits (495), Expect = 7e-51
Identities = 97/97 (100%), Positives = 97/97 (100%)
Query: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQIAES 60
MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQIAES
Sbjct: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQIAES 60
Query: 61 LFSVWSCSRRRLTNPRTRRRSPSWSLATSVTYRSSGV 97
LFSVWSCSRRRLTNPRTRRRSPSWSLATSVTYRSSGV
Sbjct: 61 LFSVWSCSRRRLTNPRTRRRSPSWSLATSVTYRSSGV 97
>gi|222136630 NFKB inhibitor interacting Ras-like 2 isoform b
[Homo sapiens]
Length = 135
Score = 115 bits (287), Expect = 1e-26
Identities = 56/57 (98%), Positives = 57/57 (100%)
Query: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQI 57
MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQ+
Sbjct: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQV 57
>gi|222136628 NFKB inhibitor interacting Ras-like 2 isoform a
[Homo sapiens]
Length = 191
Score = 115 bits (287), Expect = 1e-26
Identities = 56/57 (98%), Positives = 57/57 (100%)
Query: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQI 57
MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQ+
Sbjct: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQV 57
>gi|19072794 NFKB inhibitor interacting Ras-like 2 isoform a [Homo
sapiens]
Length = 191
Score = 115 bits (287), Expect = 1e-26
Identities = 56/57 (98%), Positives = 57/57 (100%)
Query: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQI 57
MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQ+
Sbjct: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQV 57
>gi|47777758 NFKB inhibitor interacting Ras-like 2 isoform a [Homo
sapiens]
Length = 191
Score = 115 bits (287), Expect = 1e-26
Identities = 56/57 (98%), Positives = 57/57 (100%)
Query: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQI 57
MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQ+
Sbjct: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQV 57
>gi|9966809 kappa B-ras 1 [Homo sapiens]
Length = 192
Score = 91.3 bits (225), Expect = 2e-19
Identities = 41/57 (71%), Positives = 48/57 (84%)
Query: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQI 57
MGK CKVVVCG SVGKT+ILEQLLYGNH +G E ET ED+Y+ S+ETDRGV+EQ+
Sbjct: 1 MGKGCKVVVCGLLSVGKTAILEQLLYGNHTIGMEDCETMEDVYMASVETDRGVKEQL 57
>gi|55953120 RAS-related on chromosome 22 isoform b [Homo sapiens]
Length = 115
Score = 32.7 bits (73), Expect = 0.064
Identities = 14/29 (48%), Positives = 20/29 (68%)
Query: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNH 29
MG S +V V G VGKT+I+ Q L+G++
Sbjct: 1 MGGSLRVAVLGAPGVGKTAIIRQFLFGDY 29
>gi|5454030 RAS-related on chromosome 22 isoform a [Homo sapiens]
Length = 203
Score = 32.7 bits (73), Expect = 0.064
Identities = 14/29 (48%), Positives = 20/29 (68%)
Query: 1 MGKSCKVVVCGQASVGKTSILEQLLYGNH 29
MG S +V V G VGKT+I+ Q L+G++
Sbjct: 1 MGGSLRVAVLGAPGVGKTAIIRQFLFGDY 29
>gi|4885581 Rho family GTPase 2 [Homo sapiens]
Length = 227
Score = 30.8 bits (68), Expect = 0.24
Identities = 15/47 (31%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 5 CKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDR 51
CK+VV G A GKT++L+ ++ + T + Y S E D+
Sbjct: 8 CKIVVVGDAECGKTALLQ--VFAKDAYPGSYVPTVFENYTASFEIDK 52
>gi|38201690 RAP2B, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 29.3 bits (64), Expect = 0.71
Identities = 17/45 (37%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETD 50
KVVV G VGK+++ Q + G+ + + T ED Y IE D
Sbjct: 5 KVVVLGSGGVGKSALTVQFVTGSFI--EKYDPTIEDFYRKEIEVD 47
>gi|10518344 RAP2A, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 28.9 bits (63), Expect = 0.92
Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 2/45 (4%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETD 50
KVVV G VGK+++ Q + G + + T ED Y IE D
Sbjct: 5 KVVVLGSGGVGKSALTVQFVTGTFI--EKYDPTIEDFYRKEIEVD 47
>gi|32129209 RAP2C, member of RAS oncogene family [Homo sapiens]
Length = 183
Score = 28.9 bits (63), Expect = 0.92
Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 2/45 (4%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETD 50
KVVV G VGK+++ Q + G + + T ED Y IE D
Sbjct: 5 KVVVLGSGGVGKSALTVQFVTGTFI--EKYDPTIEDFYRKEIEVD 47
>gi|11034843 ras homolog gene family, member U [Homo sapiens]
Length = 258
Score = 28.5 bits (62), Expect = 1.2
Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 3/60 (5%)
Query: 2 GKSCKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETD-RGVREQIAES 60
G+ K V+ G +VGKTS++ + Y + +E I T D + + D R VR Q+ ++
Sbjct: 47 GRGVKCVLVGDGAVGKTSLV--VSYTTNGYPTEYIPTAFDNFSAVVSVDGRPVRLQLCDT 104
>gi|7657033 5',3'-nucleotidase, cytosolic [Homo sapiens]
Length = 201
Score = 28.5 bits (62), Expect = 1.2
Identities = 16/45 (35%), Positives = 20/45 (44%)
Query: 41 DIYVGSIETDRGVREQIAESLFSVWSCSRRRLTNPRTRRRSPSWS 85
D+ + +T RG E + C R L P TRRR SWS
Sbjct: 140 DLLIDDKDTVRGQEETPSWEHILFTCCHNRHLVLPPTRRRLLSWS 184
>gi|96975135 RAB24 gene product [Homo sapiens]
Length = 203
Score = 28.1 bits (61), Expect = 1.6
Identities = 12/27 (44%), Positives = 20/27 (74%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVG 32
KVV+ G+ VGKTS++E+ ++ +VG
Sbjct: 9 KVVMLGKEYVGKTSLVERYVHDRFLVG 35
>gi|72534833 RAB24 gene product [Homo sapiens]
Length = 203
Score = 28.1 bits (61), Expect = 1.6
Identities = 12/27 (44%), Positives = 20/27 (74%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVG 32
KVV+ G+ VGKTS++E+ ++ +VG
Sbjct: 9 KVVMLGKEYVGKTSLVERYVHDRFLVG 35
>gi|24415404 MDN1, midasin homolog [Homo sapiens]
Length = 5596
Score = 28.1 bits (61), Expect = 1.6
Identities = 19/49 (38%), Positives = 28/49 (57%), Gaps = 7/49 (14%)
Query: 7 VVVCGQASVGKTSILEQL--LYGNHVV---GSEMIETQEDIYVGSIETD 50
V++ G+ SVGKTS+++ L GNH V E + QE Y+G +D
Sbjct: 1080 VLIQGETSVGKTSLIQWLAAATGNHCVRINNHEHTDIQE--YIGCYTSD 1126
>gi|4885069 ras homolog gene family, member E [Homo sapiens]
Length = 244
Score = 27.7 bits (60), Expect = 2.1
Identities = 14/46 (30%), Positives = 22/46 (47%), Gaps = 2/46 (4%)
Query: 5 CKVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETD 50
CK+VV G + GKT++L ++ + T + Y S E D
Sbjct: 24 CKIVVVGDSQCGKTALLH--VFAKDCFPENYVPTVFENYTASFEID 67
>gi|223555935 dynein, axonemal, heavy polypeptide 14 isoform 1 [Homo
sapiens]
Length = 4515
Score = 27.3 bits (59), Expect = 2.7
Identities = 10/22 (45%), Positives = 17/22 (77%)
Query: 4 SCKVVVCGQASVGKTSILEQLL 25
SC V++ G++ VGKT+ + Q+L
Sbjct: 2329 SCPVLLTGESGVGKTAAINQML 2350
>gi|4757772 DIRAS family, GTP-binding RAS-like 3 [Homo sapiens]
Length = 229
Score = 27.3 bits (59), Expect = 2.7
Identities = 17/48 (35%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGV 53
+VVV G A VGK+++L + GN E + T E+ Y + GV
Sbjct: 39 RVVVVGTAGVGKSTLLHKWASGN--FRHEYLPTIENTYCQLLGCSHGV 84
>gi|28376635 RAB37, member RAS oncogene family isoform 3 [Homo
sapiens]
Length = 216
Score = 27.3 bits (59), Expect = 2.7
Identities = 12/28 (42%), Positives = 17/28 (60%)
Query: 6 KVVVCGQASVGKTSILEQLLYGNHVVGS 33
K ++ G + VGKTS+L Q G + GS
Sbjct: 24 KTILVGDSGVGKTSLLVQFDQGKFIPGS 51
>gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo
sapiens]
Length = 1157
Score = 27.3 bits (59), Expect = 2.7
Identities = 18/64 (28%), Positives = 30/64 (46%), Gaps = 7/64 (10%)
Query: 7 VVVCGQASVGKTSILEQLLYGNHVVGSEMIETQEDIYVGSIETDRGVREQIAESLFSVWS 66
V+VCG+ GKT+ + Q LY E + ED +G E R +++ + +
Sbjct: 271 VIVCGETGSGKTTQVPQFLY-------EAGFSSEDSIIGVTEPRRVAAVAMSQRVAKEMN 323
Query: 67 CSRR 70
S+R
Sbjct: 324 LSQR 327
>gi|223671872 inhibitor of kappa light polypeptide gene enhancer in
B-cells, kinase gamma isoform c [Homo sapiens]
Length = 320
Score = 26.9 bits (58), Expect = 3.5
Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 6/38 (15%)
Query: 26 YGNH----VVGSEMIETQEDIYVGSIETDRGVREQIAE 59
Y NH VVGSE + DIY + +R RE++AE
Sbjct: 190 YDNHIKSSVVGSE--RKRADIYKADFQAERQAREKLAE 225
>gi|74096429 RAB41, member RAS oncogene family [Homo sapiens]
Length = 222
Score = 26.6 bits (57), Expect = 4.6
Identities = 10/23 (43%), Positives = 17/23 (73%)
Query: 6 KVVVCGQASVGKTSILEQLLYGN 28
K++ G+ SVGKTSI+ + +Y +
Sbjct: 33 KLLFLGEQSVGKTSIISRFMYNS 55
>gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens]
Length = 1015
Score = 26.2 bits (56), Expect = 6.0
Identities = 11/19 (57%), Positives = 14/19 (73%)
Query: 6 KVVVCGQASVGKTSILEQL 24
+VVV G S GKTS+LE +
Sbjct: 345 RVVVVGDQSAGKTSVLEMI 363
>gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens]
Length = 997
Score = 26.2 bits (56), Expect = 6.0
Identities = 11/19 (57%), Positives = 14/19 (73%)
Query: 6 KVVVCGQASVGKTSILEQL 24
+VVV G S GKTS+LE +
Sbjct: 327 RVVVVGDQSAGKTSVLEMI 345
>gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens]
Length = 979
Score = 26.2 bits (56), Expect = 6.0
Identities = 11/19 (57%), Positives = 14/19 (73%)
Query: 6 KVVVCGQASVGKTSILEQL 24
+VVV G S GKTS+LE +
Sbjct: 309 RVVVVGDQSAGKTSVLEMI 327
>gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens]
Length = 978
Score = 26.2 bits (56), Expect = 6.0
Identities = 11/19 (57%), Positives = 14/19 (73%)
Query: 6 KVVVCGQASVGKTSILEQL 24
+VVV G S GKTS+LE +
Sbjct: 308 RVVVVGDQSAGKTSVLEMI 326
>gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens]
Length = 961
Score = 26.2 bits (56), Expect = 6.0
Identities = 11/19 (57%), Positives = 14/19 (73%)
Query: 6 KVVVCGQASVGKTSILEQL 24
+VVV G S GKTS+LE +
Sbjct: 291 RVVVVGDQSAGKTSVLEMI 309
>gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens]
Length = 942
Score = 26.2 bits (56), Expect = 6.0
Identities = 11/19 (57%), Positives = 14/19 (73%)
Query: 6 KVVVCGQASVGKTSILEQL 24
+VVV G S GKTS+LE +
Sbjct: 272 RVVVVGDQSAGKTSVLEMI 290
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.129 0.375
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,440,657
Number of Sequences: 37866
Number of extensions: 114884
Number of successful extensions: 478
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 449
Number of HSP's gapped (non-prelim): 52
length of query: 97
length of database: 18,247,518
effective HSP length: 68
effective length of query: 29
effective length of database: 15,672,630
effective search space: 454506270
effective search space used: 454506270
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.