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Search of human proteins with 222080109
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|222080109 orexin receptor 2 [Homo sapiens]
(444 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|222080109 orexin receptor 2 [Homo sapiens] 910 0.0
gi|222080095 orexin receptor 1 [Homo sapiens] 563 e-160
gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens] 197 2e-50
gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens] 197 2e-50
gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens] 197 2e-50
gi|11545887 neuropeptide FF receptor 1 [Homo sapiens] 192 4e-49
gi|157738685 G protein-coupled receptor 103 [Homo sapiens] 168 8e-42
gi|223633971 G protein-coupled receptor 83 [Homo sapiens] 164 1e-40
gi|4758474 G protein-coupled receptor 10 [Homo sapiens] 159 4e-39
gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens] 158 1e-38
gi|28875799 cholecystokinin B receptor [Homo sapiens] 155 5e-38
gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens] 154 1e-37
gi|4502607 cholecystokinin A receptor [Homo sapiens] 148 1e-35
gi|7669548 tachykinin receptor 3 [Homo sapiens] 147 2e-35
gi|157364957 pancreatic polypeptide receptor 1 [Homo sapiens] 144 2e-34
gi|4885361 gastrin-releasing peptide receptor [Homo sapiens] 140 2e-33
gi|239757761 PREDICTED: similar to gastrin-releasing peptide rec... 140 2e-33
gi|157426873 tachykinin receptor 2 [Homo sapiens] 140 2e-33
gi|4502455 bombesin-like receptor 3 [Homo sapiens] 139 5e-33
gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens] 138 9e-33
gi|62865887 G protein-coupled receptor 54 [Homo sapiens] 138 1e-32
gi|4557265 beta-1-adrenergic receptor [Homo sapiens] 137 2e-32
gi|4503905 galanin receptor 2 [Homo sapiens] 137 2e-32
gi|4507681 thyrotropin-releasing hormone receptor [Homo sapiens] 135 6e-32
gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens] 133 3e-31
gi|161484640 neuromedin B receptor [Homo sapiens] 130 2e-30
gi|39725940 opioid receptor, kappa 1 [Homo sapiens] 129 5e-30
gi|21426829 prokineticin receptor 2 [Homo sapiens] 126 3e-29
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens] 126 5e-29
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens] 125 1e-28
>gi|222080109 orexin receptor 2 [Homo sapiens]
Length = 444
Score = 910 bits (2352), Expect = 0.0
Identities = 444/444 (100%), Positives = 444/444 (100%)
Query: 1 MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG 60
MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
Sbjct: 1 MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG 60
Query: 61 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW 120
YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
Sbjct: 61 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW 120
Query: 121 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS 180
FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
Sbjct: 121 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS 180
Query: 181 CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV 240
CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
Sbjct: 181 CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV 240
Query: 241 LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARR 300
LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARR
Sbjct: 241 LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARR 300
Query: 301 KTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAAN 360
KTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAAN
Sbjct: 301 KTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAAN 360
Query: 361 PIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFDNISKL 420
PIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFDNISKL
Sbjct: 361 PIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFDNISKL 420
Query: 421 SEQVVLTSISTLPAANGAGPLQNW 444
SEQVVLTSISTLPAANGAGPLQNW
Sbjct: 421 SEQVVLTSISTLPAANGAGPLQNW 444
>gi|222080095 orexin receptor 1 [Homo sapiens]
Length = 425
Score = 563 bits (1450), Expect = e-160
Identities = 284/413 (68%), Positives = 334/413 (80%), Gaps = 10/413 (2%)
Query: 24 TQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNH 83
++EP P DY+DE FLRYLWR+YL+PK+YEWVLIA Y+ VFVVAL+GN LVC+AVW+NH
Sbjct: 17 SREPSPVPPDYEDE-FLRYLWRDYLYPKQYEWVLIAAYVAVFVVALVGNTLVCLAVWRNH 75
Query: 84 HMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVL 143
HMRTVTNYFIVNLSLADVLVT CLPA+L+VDITE+W FG +LCKVIPYLQ VSVSV+VL
Sbjct: 76 HMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCKVIPYLQAVSVSVAVL 135
Query: 144 TLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVSCIIMIPQAIVMECSTVFPGLANK 203
TLS IALDRWYAICHPL+FKSTA+RAR SI+ IW VS IM+PQA VMECS+V P LAN+
Sbjct: 136 TLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQAAVMECSSVLPELANR 195
Query: 204 TTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQ 263
T LF+VCDERW ++YPK+YH CFF+VTY+APL LM +AY QIFRKLW RQIPGT+S +
Sbjct: 196 TRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFRKLWGRQIPGTTSALV 255
Query: 264 RKWKPLQPVSQ----PRGPGQPTKSRMSAVAAEIKQIRARRKTARMLMIVLLVFAICYLP 319
R WK +P Q +G + R A AE+KQ+RARRKTA+MLM+VLLVFA+CYLP
Sbjct: 256 RNWK--RPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKMLMVVLLVFALCYLP 313
Query: 320 ISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAF 379
IS+LNVLKRVFGMF DRE VYA FTFSHWLVYANSAANPIIYNFLSGKFRE+FKAAF
Sbjct: 314 ISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNFLSGKFREQFKAAF 373
Query: 380 SCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFDNISKLSEQVVLTSISTL 432
SCC G+ + R+S S KSL+ Q + +ISK+SE VVLTS++T+
Sbjct: 374 SCCLPGLGPCGSLKAPSPRSSA-SHKSLSLQ--SRCSISKISEHVVLTSVTTV 423
>gi|16604258 neuropeptide FF receptor 2 isoform 2 [Homo sapiens]
Length = 420
Score = 197 bits (501), Expect = 2e-50
Identities = 119/377 (31%), Positives = 190/377 (50%), Gaps = 39/377 (10%)
Query: 8 DSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVV 67
D+ NW +N+T+ + + ++ Y YLH + + I Y ++F +
Sbjct: 6 DTNSSENWHPIWNVNDTKHHLYSDINIT---YVNY----YLHQPQVAAIFIISYFLIFFL 58
Query: 68 ALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLC 127
++GN +VC V +N HM TVTN FI+NL+++D+LV I C+P TL+ +I W FG ++C
Sbjct: 59 CMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMC 118
Query: 128 KVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVSCIIMIPQ 187
K+ +Q +SV+ SV TL IA+DR+ + +P K T K A I+IIW+++ IM P
Sbjct: 119 KISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPS 178
Query: 188 AIVMECS-----TVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMVLA 242
A+++ V NKT+ C E W + K+Y F Y+APL L+V+
Sbjct: 179 AVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIM 238
Query: 243 YLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARRKT 302
Y +I L+ +P T Q +W + R ++K
Sbjct: 239 YGRIGISLFRAAVPHTGRKNQEQWHVVS--------------------------RKKQKI 272
Query: 303 ARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAANPI 362
+ML+IV L+F + +LP+ L +L + + +Y + F+HWL + NS+ NPI
Sbjct: 273 IKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYI-YPFAHWLAFGNSSVNPI 331
Query: 363 IYNFLSGKFREEFKAAF 379
IY F + FR F+ AF
Sbjct: 332 IYGFFNENFRRGFQEAF 348
>gi|221316654 neuropeptide FF receptor 2 isoform 1 [Homo sapiens]
Length = 522
Score = 197 bits (501), Expect = 2e-50
Identities = 119/377 (31%), Positives = 190/377 (50%), Gaps = 39/377 (10%)
Query: 8 DSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVV 67
D+ NW +N+T+ + + ++ Y YLH + + I Y ++F +
Sbjct: 108 DTNSSENWHPIWNVNDTKHHLYSDINIT---YVNY----YLHQPQVAAIFIISYFLIFFL 160
Query: 68 ALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLC 127
++GN +VC V +N HM TVTN FI+NL+++D+LV I C+P TL+ +I W FG ++C
Sbjct: 161 CMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMC 220
Query: 128 KVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVSCIIMIPQ 187
K+ +Q +SV+ SV TL IA+DR+ + +P K T K A I+IIW+++ IM P
Sbjct: 221 KISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPS 280
Query: 188 AIVMECS-----TVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMVLA 242
A+++ V NKT+ C E W + K+Y F Y+APL L+V+
Sbjct: 281 AVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIM 340
Query: 243 YLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARRKT 302
Y +I L+ +P T Q +W + R ++K
Sbjct: 341 YGRIGISLFRAAVPHTGRKNQEQWHVVS--------------------------RKKQKI 374
Query: 303 ARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAANPI 362
+ML+IV L+F + +LP+ L +L + + +Y + F+HWL + NS+ NPI
Sbjct: 375 IKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYI-YPFAHWLAFGNSSVNPI 433
Query: 363 IYNFLSGKFREEFKAAF 379
IY F + FR F+ AF
Sbjct: 434 IYGFFNENFRRGFQEAF 450
>gi|221316652 neuropeptide FF receptor 2 isoform 3 [Homo sapiens]
Length = 423
Score = 197 bits (501), Expect = 2e-50
Identities = 119/377 (31%), Positives = 190/377 (50%), Gaps = 39/377 (10%)
Query: 8 DSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVV 67
D+ NW +N+T+ + + ++ Y YLH + + I Y ++F +
Sbjct: 9 DTNSSENWHPIWNVNDTKHHLYSDINIT---YVNY----YLHQPQVAAIFIISYFLIFFL 61
Query: 68 ALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLC 127
++GN +VC V +N HM TVTN FI+NL+++D+LV I C+P TL+ +I W FG ++C
Sbjct: 62 CMMGNTVVCFIVMRNKHMHTVTNLFILNLAISDLLVGIFCMPITLLDNIIAGWPFGNTMC 121
Query: 128 KVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVSCIIMIPQ 187
K+ +Q +SV+ SV TL IA+DR+ + +P K T K A I+IIW+++ IM P
Sbjct: 122 KISGLVQGISVAASVFTLVAIAVDRFQCVVYPFKPKLTIKTAFVIIMIIWVLAITIMSPS 181
Query: 188 AIVMECS-----TVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMVLA 242
A+++ V NKT+ C E W + K+Y F Y+APL L+V+
Sbjct: 182 AVMLHVQEEKYYRVRLNSQNKTSPVYWCREDWPNQEMRKIYTTVLFANIYLAPLSLIVIM 241
Query: 243 YLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARRKT 302
Y +I L+ +P T Q +W + R ++K
Sbjct: 242 YGRIGISLFRAAVPHTGRKNQEQWHVVS--------------------------RKKQKI 275
Query: 303 ARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAANPI 362
+ML+IV L+F + +LP+ L +L + + +Y + F+HWL + NS+ NPI
Sbjct: 276 IKMLLIVALLFILSWLPLWTLMMLSDYADLSPNELQIINIYI-YPFAHWLAFGNSSVNPI 334
Query: 363 IYNFLSGKFREEFKAAF 379
IY F + FR F+ AF
Sbjct: 335 IYGFFNENFRRGFQEAF 351
>gi|11545887 neuropeptide FF receptor 1 [Homo sapiens]
Length = 430
Score = 192 bits (489), Expect = 4e-49
Identities = 130/375 (34%), Positives = 189/375 (50%), Gaps = 43/375 (11%)
Query: 10 PPCRNWS-SASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVVA 68
PP +W S + N P N T F Y Y H + I Y ++F++
Sbjct: 8 PPNSSWPLSQNGTNTEATPATNLT------FSSY----YQHTSPVAAMFIVAYALIFLLC 57
Query: 69 LIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCK 128
++GN LVC V KN HM TVTN FI+NL+++D+LV I C+P TLV ++ W F + CK
Sbjct: 58 MVGNTLVCFIVLKNRHMHTVTNMFILNLAVSDLLVGIFCMPTTLVDNLITGWPFDNATCK 117
Query: 129 VIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVSCIIMIPQA 188
+ +Q +SVS SV TL IA++R+ I HP K T ++A +I +IW ++ +IM P A
Sbjct: 118 MSGLVQGMSVSASVFTLVAIAVERFRCIVHPFREKLTLRKALVTIAVIWALALLIMCPSA 177
Query: 189 IVM----ECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMVLAYL 244
+ + E N++ C E W + ++Y F Y+APL L+V+ Y
Sbjct: 178 VTLTVTREEHHFMVDARNRSYPLYSCWEAWPEKGMRRVYTTVLFSHIYLAPLALIVVMYA 237
Query: 245 QIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARRKTAR 304
+I RKL Q PG + PG AA+ + R R +
Sbjct: 238 RIARKLC--QAPGPA------------------PG-------GEEAADPRASRRRARVVH 270
Query: 305 MLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAANPIIY 364
ML++V L F + +LP+ L +L + A TVYA F F+HWL + NS+ANPIIY
Sbjct: 271 MLVMVALFFTLSWLPLWALLLLIDYGQLSAPQLHLVTVYA-FPFAHWLAFFNSSANPIIY 329
Query: 365 NFLSGKFREEFKAAF 379
+ + FR F+AAF
Sbjct: 330 GYFNENFRRGFQAAF 344
>gi|157738685 G protein-coupled receptor 103 [Homo sapiens]
Length = 431
Score = 168 bits (426), Expect = 8e-42
Identities = 102/373 (27%), Positives = 193/373 (51%), Gaps = 37/373 (9%)
Query: 21 LNETQEPF---LNPTDYDDEEFLR-YLWREYLH----PKEYEWVLIAGYIIVFVVALIGN 72
LN T E F L + E+F+ Y R ++ P + L+ +++F +AL GN
Sbjct: 4 LNITPEQFSRLLRDHNLTREQFIALYRLRPLVYTPELPGRAKLALVLTGVLIFALALFGN 63
Query: 73 VLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPY 132
LV V ++ MRTVTN FI +L+L+D+L+T C+P T++ +I++ W G +CK++P+
Sbjct: 64 ALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWLGGAFICKMVPF 123
Query: 133 LQTVSVSVSVLTLSCIALDRWYAICHPLMFK--STAKRARNSIVIIWIVSCIIMIPQAIV 190
+Q+ +V +LT++CIA++R + HP K T +RA + ++W+V+ I+ P V
Sbjct: 124 VQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVAVIVGSPMWHV 183
Query: 191 MECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKL 250
+ + L K + C E W ++ K+Y ++ ++ PL +M++ Y +I +L
Sbjct: 184 QQLEIKYDFLYEKEHI--CCLEEWTSPVHQKIYTTFILVILFLLPLMVMLILYSKIGYEL 241
Query: 251 WCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARRKTARMLMI-V 309
W ++ G SV++ + E+ +I ++K A ++M+ V
Sbjct: 242 WIKKRVGDGSVLR-----------------------TIHGKEMSKIARKKKRAVIMMVTV 278
Query: 310 LLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSG 369
+ +FA+C+ P +++++ + F D T+ F + ++NS NPI+Y F++
Sbjct: 279 VALFAVCWAPFHVVHMMIE-YSNFEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNE 337
Query: 370 KFREEFKAAFSCC 382
F++ +A C
Sbjct: 338 NFKKNVLSAVCYC 350
>gi|223633971 G protein-coupled receptor 83 [Homo sapiens]
Length = 423
Score = 164 bits (416), Expect = 1e-40
Identities = 102/330 (30%), Positives = 169/330 (51%), Gaps = 42/330 (12%)
Query: 56 VLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVD 115
+LI Y + V +L GNVLVC ++KN M + T+ FIVNL++AD+++T+ P TLV
Sbjct: 73 LLIVAYSFIIVFSLFGNVLVCHVIFKNQRMHSATSLFIVNLAVADIMITLLNTPFTLVRF 132
Query: 116 ITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVI 175
+ TW FG+ +C V + Q S+ VS LTL+ IA+DR I HPL + + + I +
Sbjct: 133 VNSTWIFGKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQVIMHPLKPRISITKGVIYIAV 192
Query: 176 IWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVC--DERWGGEIYPKMYHICFFLVTYM 233
IW ++ +P AI C +F ++ + ++C D +++ K + F++ Y+
Sbjct: 193 IWTMATFFSLPHAI---CQKLFTFKYSEDIVRSLCLPDFPEPADLFWKYLDLATFILLYI 249
Query: 234 APLCLMVLAYLQIFRKLW-CRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAE 292
PL ++ +AY ++ +KLW C I G T + A+
Sbjct: 250 LPLLIISVAYARVAKKLWLCNMI-----------------------GDVTTEQYFALR-- 284
Query: 293 IKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWL 352
R ++KT +MLM+V+++FA+C+ P++ +L + R +F F HW
Sbjct: 285 ----RKKKKTIKMLMLVVVLFALCWFPLNCYVLL------LSSKVIRTNNALYFAF-HWF 333
Query: 353 VYANSAANPIIYNFLSGKFREEFKAAFSCC 382
+++ NP IY +L+ FR E KA S C
Sbjct: 334 AMSSTCYNPFIYCWLNENFRIELKALLSMC 363
>gi|4758474 G protein-coupled receptor 10 [Homo sapiens]
Length = 370
Score = 159 bits (403), Expect = 4e-39
Identities = 97/323 (30%), Positives = 166/323 (51%), Gaps = 39/323 (12%)
Query: 56 VLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVD 115
+++ Y +V VV L+GN L+ + + + + VTN+ I NL+L+DVL+ C+P TL
Sbjct: 62 LIVLLYSVVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCTACVPLTLAYA 121
Query: 116 ITET-WFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIV 174
W FG LC ++ +LQ V+V VSV TL+ IA+DR+ + HPL + + + + +++
Sbjct: 122 FEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLRRRISLRLSAYAVL 181
Query: 175 IIWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGG-EIYPKMYHICFFLVTYM 233
IW +S ++ +P A+ + P +C+E WG E ++Y LVTY+
Sbjct: 182 AIWALSAVLALPAAVHTYHVELKPHDVR------LCEEFWGSQERQRQLYAWGLLLVTYL 235
Query: 234 APLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEI 293
PL +++L+Y+++ KL R +PG + Q W +
Sbjct: 236 LPLLVILLSYVRVSVKLRNRVVPGCVTQSQADWDRAR----------------------- 272
Query: 294 KQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLV 353
RR+T +L++V++VFA+C+LP+ + N+L+ + H D HWL
Sbjct: 273 -----RRRTFCLLVVVVVVFAVCWLPLHVFNLLR---DLDPHAIDPYAFGLVQLLCHWLA 324
Query: 354 YANSAANPIIYNFLSGKFREEFK 376
+++ NP IY +L FREE +
Sbjct: 325 MSSACYNPFIYAWLHDSFREELR 347
>gi|4505447 neuropeptide Y receptor Y2 [Homo sapiens]
Length = 381
Score = 158 bits (399), Expect = 1e-38
Identities = 103/335 (30%), Positives = 166/335 (49%), Gaps = 45/335 (13%)
Query: 52 EYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPAT 111
E + VLI Y + ++ +IGN LV V K MRTVTN+FI NL++AD+LV CLP T
Sbjct: 48 EVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFT 107
Query: 112 LVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARN 171
L + W G LC ++PY Q ++V VS +TL+ IALDR I + L K + + +
Sbjct: 108 LTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFL 167
Query: 172 SIVIIWIVSCIIMIPQAIVMECS--TVFPGLANKTTLFTVCDERWGGE---IYPKMYHIC 226
I + W +S ++ P AI E S + P C E+W GE IY +Y +
Sbjct: 168 IIGLAWGISALLASPLAIFREYSLIEIIPDFE-----IVACTEKWPGEEKSIYGTVYSLS 222
Query: 227 FFLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRM 286
L+ Y+ PL ++ +Y +I+ KL K+ +
Sbjct: 223 SLLILYVLPLGIISFSYTRIWSKL--------------------------------KNHV 250
Query: 287 SAVAAEIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWF 346
S AA + R+KT +ML+ V++VFA+ +LP+ + + ++ + + F
Sbjct: 251 SPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLI---F 307
Query: 347 TFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSC 381
T H + ++ ANP++Y +++ +R+ F +AF C
Sbjct: 308 TVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRC 342
>gi|28875799 cholecystokinin B receptor [Homo sapiens]
Length = 447
Score = 155 bits (393), Expect = 5e-38
Identities = 101/369 (27%), Positives = 179/369 (48%), Gaps = 56/369 (15%)
Query: 56 VLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVD 115
+ I Y ++F++++ GN+L+ V + + +RTVTN F+++L+++D+L+ + C+P TL+ +
Sbjct: 56 IRITLYAVIFLMSVGGNMLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPN 115
Query: 116 ITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFK--STAKRARNSI 173
+ T+ FG +CK + YL VSVSVS L+L IAL+R+ AIC PL + T A I
Sbjct: 116 LMGTFIFGTVICKAVSYLMGVSVSVSTLSLVAIALERYSAICRPLQARVWQTRSHAARVI 175
Query: 174 VIIWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYM 233
V W++S ++M+P + V P + C RW + + + L+ +
Sbjct: 176 VATWLLSGLLMVPYPVYTVVQPVGPRVLQ-------CVHRWPSARVRQTWSVLLLLLLFF 228
Query: 234 APLCLMVLAYLQIFRKLW--------------------------------CRQIPGTSS- 260
P +M +AY I R+L+ CR G
Sbjct: 229 IPGVVMAVAYGLISRELYLGLRFDGDSDSDSQSRVRNQGGLPGAVHQNGRCRPETGAVGE 288
Query: 261 ------VVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARRKTARMLMIVLLVFA 314
V + +P ++ PG + SR + ++ A+++ RML++++++F
Sbjct: 289 DSDGCYVQLPRSRPALELTALTAPGPGSGSRPTQA-----KLLAKKRVVRMLLVIVVLFF 343
Query: 315 ICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREE 374
+C+LP+ N + G AH R A +F H L YA++ NP++Y F+ +FR+
Sbjct: 344 LCWLPVYSANTWRAFDGPGAH---RALSGAPISFIHLLSYASACVNPLVYCFMHRRFRQA 400
Query: 375 FKAAFSCCC 383
+ CC
Sbjct: 401 CLETCARCC 409
>gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens]
Length = 407
Score = 154 bits (390), Expect = 1e-37
Identities = 99/359 (27%), Positives = 165/359 (45%), Gaps = 51/359 (14%)
Query: 27 PFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMR 86
P ++ + +F++ W+ L W A Y ++ V +++GNV+V + + MR
Sbjct: 13 PNISTNTSEPNQFVQPAWQIVL------WA--AAYTVIVVTSVVGNVVVMWIILAHKRMR 64
Query: 87 TVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLS 146
TVTNYF+VNL+ A+ + + W++G CK + +V S+ +++
Sbjct: 65 TVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMT 124
Query: 147 CIALDRWYAICHPLMFKSTAKRARNSIVIIWIVSCIIMIPQAIVMECSTVFPGLANKTTL 206
+A DR+ AI HPL + +A + I +IW+++ ++ PQ T+
Sbjct: 125 AVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETM--------PS 176
Query: 207 FTVCDERW---GGEIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQ 263
VC W +IY K+YHIC ++ Y PL ++ AY + LW +IPG SS
Sbjct: 177 RVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRY 236
Query: 264 RKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARRKTARMLMIVLLVFAICYLPISIL 323
+Q+ A+RK +M+++V+ FAIC+LP I
Sbjct: 237 H-----------------------------EQVSAKRKVVKMMIVVVCTFAICWLPFHIF 267
Query: 324 NVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCC 382
+L + + + VY WL +++ NPIIY L+ +FR FK AF CC
Sbjct: 268 FLLPYINPDLYLKKFIQQVYLAIM---WLAMSSTMYNPIIYCCLNDRFRLGFKHAFRCC 323
>gi|4502607 cholecystokinin A receptor [Homo sapiens]
Length = 428
Score = 148 bits (373), Expect = 1e-35
Identities = 96/357 (26%), Positives = 175/357 (49%), Gaps = 34/357 (9%)
Query: 54 EW---VLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPA 110
EW V I Y ++F+++++GN LV + +N MRTVTN F+++L+++D+++ + C+P
Sbjct: 38 EWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPF 97
Query: 111 TLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFK--STAKR 168
L+ ++ + + FG ++CK Y SVSVS L I+L+R+ AIC PL + T
Sbjct: 98 NLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSH 157
Query: 169 ARNSIVIIWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFF 228
A I W +S IM P I S + P N +C ++ + +H
Sbjct: 158 ALKVIAATWCLSFTIMTPYPIY---SNLVPFTKNNNQTANMCRFLLPNDVMQQSWHTFLL 214
Query: 229 LVTYMAPLCLMVLAY----LQIF---------RKLWCRQIPGTSS----------VVQRK 265
L+ ++ P +M++AY L+++ +K + P T+S +Q+
Sbjct: 215 LILFLIPGIVMMVAYGLISLELYQGIKFEASQKKSAKERKPSTTSSGKYEDSDGCYLQKT 274
Query: 266 WKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARRKTARMLMIVLLVFAICYLPISILNV 325
P + + G +++ + + A+++ RML++++++F +C++PI N
Sbjct: 275 RPPRKLELRQLSTGSSSRANRIRSNSSAANLMAKKRVIRMLIVIVVLFFLCWMPIFSANA 334
Query: 326 LKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCC 382
+ + +R +F L Y +S NPIIY F++ +FR F A F CC
Sbjct: 335 WR---AYDTASAERRLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCC 388
>gi|7669548 tachykinin receptor 3 [Homo sapiens]
Length = 465
Score = 147 bits (370), Expect = 2e-35
Identities = 102/358 (28%), Positives = 171/358 (47%), Gaps = 53/358 (14%)
Query: 26 EPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHM 85
+P+ N T+ +F++ WR L W L G +V VA++GN++V + + M
Sbjct: 69 QPWANLTN----QFVQPSWRIAL------WSLAYG--VVVAVAVLGNLIVIWIILAHKRM 116
Query: 86 RTVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTL 145
RTVTNYF+VNL+ +D + + + W+FG + C+ + +V S+ ++
Sbjct: 117 RTVTNYFLVNLAFSDASMAAFNTLVNFIYALHSEWYFGANYCRFQNFFPITAVFASIYSM 176
Query: 146 SCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVSCIIMIPQAIVMECSTVFPGLANKTT 205
+ IA+DR+ AI PL + +A + I IWI++ ++ PQ + + + V PG
Sbjct: 177 TAIAVDRYMAIIDPLKPRLSATATKIVIGSIWILAFLLAFPQCLYSK-TKVMPGR----- 230
Query: 206 LFTVCDERW-GGEIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQR 264
T+C +W G YHI ++ Y PL +M + Y + LW +IPG +
Sbjct: 231 --TLCFVQWPEGPKQHFTYHIIVIILVYCFPLLIMGITYTIVGITLWGGEIPGDTCDKYH 288
Query: 265 KWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARRKTARMLMIVLLVFAICYLPISILN 324
+Q++A+RK +M++IV++ FAIC+LP I
Sbjct: 289 -----------------------------EQLKAKRKVVKMMIIVVMTFAICWLPYHIYF 319
Query: 325 VLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCC 382
+L ++ + + VY S WL +++ NPIIY L+ +FR FK AF C
Sbjct: 320 ILTAIYQQLNRWKYIQQVY---LASFWLAMSSTMYNPIIYCCLNKRFRAGFKRAFRWC 374
>gi|157364957 pancreatic polypeptide receptor 1 [Homo sapiens]
Length = 375
Score = 144 bits (362), Expect = 2e-34
Identities = 101/356 (28%), Positives = 167/356 (46%), Gaps = 43/356 (12%)
Query: 57 LIAGYIIVFVVALIGNV-LVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVD 115
++ Y I VV ++GN+ L+CV V + VTN I NL+ +D L+ + C P T V
Sbjct: 44 IVTSYSIETVVGVLGNLCLMCVTV-RQKEKANVTNLLIANLAFSDFLMCLLCQPLTAVYT 102
Query: 116 ITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVI 175
I + W FG++LCK+ ++Q +SV+VS+L+L +AL+R I +P +K + +A IV+
Sbjct: 103 IMDYWIFGETLCKMSAFIQCMSVTVSILSLVLVALERHQLIINPTGWKPSISQAYLGIVL 162
Query: 176 IWIVSCIIMIPQAIVMECSTVFPGLANKTTLF----TVCDERWGGEIYPKMYHICFFLVT 231
IW+++C++ +P VF +K F VC E W + +Y L
Sbjct: 163 IWVIACVLSLPFLANSILENVFHKNHSKALEFLADKVVCTESWPLAHHRTIYTTFLLLFQ 222
Query: 232 YMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAA 291
Y PL +++ Y +I+R+L QR+ + K S A
Sbjct: 223 YCLPLGFILVCYARIYRRL------------QRQGRVFH------------KGTYSLRAG 258
Query: 292 EIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYA--WFTFS 349
+KQ+ +L+++++ FA+ +LP+ + N L+ H E + F
Sbjct: 259 HMKQVNV------VLVVMVVAFAVLWLPLHVFNSLED-----WHHEAIPICHGNLIFLVC 307
Query: 350 HWLVYANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRK 405
H L A++ NP IY FL+ F++E KA C + + L TE K
Sbjct: 308 HLLAMASTCVNPFIYGFLNTNFKKEIKALVLTCQQSAPLEESEHLPLSTVHTEVSK 363
>gi|4885361 gastrin-releasing peptide receptor [Homo sapiens]
Length = 384
Score = 140 bits (354), Expect = 2e-33
Identities = 99/369 (26%), Positives = 172/369 (46%), Gaps = 39/369 (10%)
Query: 55 WVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVV 114
+V+ A Y ++ ++ LIGN+ + MR V N FI +L+L D+L+ ITC P
Sbjct: 41 YVIPAVYGVIILIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASR 100
Query: 115 DITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSI- 173
+ + W FG+ CK+IP++Q SV VSV TL+ ++ DR+ AI P+ +++ + +
Sbjct: 101 YLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLK 160
Query: 174 -VIIWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTY 232
IWI+S ++ IP+A+ + N+ T + E++PK++ + FLV Y
Sbjct: 161 AAFIWIISMLLAIPEAVFSDLHPFHEESTNQ-TFISCAPYPHSNELHPKIHSMASFLVFY 219
Query: 233 MAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAE 292
+ PL ++ + Y I + L +Q + P + +
Sbjct: 220 VIPLSIISVYYYFIAKNL-----------IQSAY------------NLPVEGNIHVK--- 253
Query: 293 IKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFS--- 349
KQI +R++ A+ +++ + +FA C+LP ++ + + H + +T F S
Sbjct: 254 -KQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSY-----HYSEVDTSMLHFVTSICA 307
Query: 350 HWLVYANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTT 409
L + NS NP LS FR++F CC G+ R R T S KS
Sbjct: 308 RLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIRSHS-TGRSTTCMTSLKSTNP 366
Query: 410 QISNFDNIS 418
++ F I+
Sbjct: 367 SVATFSLIN 375
>gi|239757761 PREDICTED: similar to gastrin-releasing peptide
receptor [Homo sapiens]
Length = 368
Score = 140 bits (354), Expect = 2e-33
Identities = 99/369 (26%), Positives = 172/369 (46%), Gaps = 39/369 (10%)
Query: 55 WVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVV 114
+V+ A Y ++ ++ LIGN+ + MR V N FI +L+L D+L+ ITC P
Sbjct: 25 YVIPAVYGVIILIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASR 84
Query: 115 DITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSI- 173
+ + W FG+ CK+IP++Q SV VSV TL+ ++ DR+ AI P+ +++ + +
Sbjct: 85 YLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLK 144
Query: 174 -VIIWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTY 232
IWI+S ++ IP+A+ + N+ T + E++PK++ + FLV Y
Sbjct: 145 AAFIWIISMLLAIPEAVFSDLHPFHEESTNQ-TFISCAPYPHSNELHPKIHSMASFLVFY 203
Query: 233 MAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAE 292
+ PL ++ + Y I + L +Q + P + +
Sbjct: 204 VIPLSIISVYYYFIAKNL-----------IQSAY------------NLPVEGNIHVK--- 237
Query: 293 IKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFS--- 349
KQI +R++ A+ +++ + +FA C+LP ++ + + H + +T F S
Sbjct: 238 -KQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSY-----HYSEVDTSMLHFVTSICA 291
Query: 350 HWLVYANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTT 409
L + NS NP LS FR++F CC G+ R R T S KS
Sbjct: 292 RLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIRSHS-TGRSTTCMTSLKSTNP 350
Query: 410 QISNFDNIS 418
++ F I+
Sbjct: 351 SVATFSLIN 359
>gi|157426873 tachykinin receptor 2 [Homo sapiens]
Length = 398
Score = 140 bits (353), Expect = 2e-33
Identities = 101/346 (29%), Positives = 162/346 (46%), Gaps = 39/346 (11%)
Query: 61 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW 120
Y+ + +VA+ GN +V + + MRTVTNYFIVNL+LAD+ + V W
Sbjct: 40 YLALVLVAVTGNAIVIWIILAHRRMRTVTNYFIVNLALADLCMAAFNAAFNFVYASHNIW 99
Query: 121 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS 180
+FG++ C ++ VS+ +++ IA DR+ AI HP + +A + I IW+V+
Sbjct: 100 YFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSAPSTKAVIAGIWLVA 159
Query: 181 CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV 240
+ PQ STV T E GG+ +YH+ + Y PL +M
Sbjct: 160 LALASPQCFY---STVTMD-QGATKCVVAWPEDSGGKTL-LLYHLVVIALIYFLPLAVMF 214
Query: 241 LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARR 300
+AY I LW R +PG A A ++ ++A +
Sbjct: 215 VAYSVIGLTLWRRAVPGHQ----------------------------AHGANLRHLQAMK 246
Query: 301 KTARMLMIVLLVFAICYLPISILNVLKRVF-GMFAHTEDRETVYAWFTFSHWLVYANSAA 359
K + +++V+L FAIC+LP + +L ++ H ++ A F WL +++
Sbjct: 247 KFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALF----WLAMSSTMY 302
Query: 360 NPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRK 405
NPIIY L+ +FR F+ AF CC V +ED+L T++ S +
Sbjct: 303 NPIIYCCLNHRFRSGFRLAFR-CCPWVTPTKEDKLELTPTTSLSTR 347
>gi|4502455 bombesin-like receptor 3 [Homo sapiens]
Length = 399
Score = 139 bits (350), Expect = 5e-33
Identities = 92/325 (28%), Positives = 160/325 (49%), Gaps = 33/325 (10%)
Query: 61 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW 120
Y ++ V ++GN ++ +K M+TV N FI +L+ D+L+ +TC+P + E W
Sbjct: 54 YAVIISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGW 113
Query: 121 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVI--IWI 178
FG+ CKV+ +++ SV VSV TL+ ++ DR+ A+ PL + + + + +WI
Sbjct: 114 LFGRIGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSNAILKTCVKAGCVWI 173
Query: 179 VSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDER-WGGEIYPKMYHICFFLVTYMAPLC 237
VS I +P+AI T NK F C ++ +++ + FLV Y+ PL
Sbjct: 174 VSMIFALPEAIFSNVYTFRD--PNKNMTFESCTSYPVSKKLLQEIHSLLCFLVFYIIPLS 231
Query: 238 LMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIR 297
++ + Y I R L+ T ++ PT+ + A KQI
Sbjct: 232 IISVYYSLIARTLY----KSTLNI-------------------PTEEQSHAR----KQIE 264
Query: 298 ARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANS 357
+R++ AR +++++ +FA+C+LP +L L F + + + + FS L ++NS
Sbjct: 265 SRKRIARTVLVLVALFALCWLPNHLL-YLYHSFTSQTYVDPSAMHFIFTIFSRVLAFSNS 323
Query: 358 AANPIIYNFLSGKFREEFKAAFSCC 382
NP +LS F++ FKA CC
Sbjct: 324 CVNPFALYWLSKSFQKHFKAQLFCC 348
>gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens]
Length = 311
Score = 138 bits (348), Expect = 9e-33
Identities = 91/347 (26%), Positives = 157/347 (45%), Gaps = 51/347 (14%)
Query: 27 PFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMR 86
P ++ + +F++ W+ L W A Y ++ V +++GNV+V + + MR
Sbjct: 13 PNISTNTSEPNQFVQPAWQIVL------WA--AAYTVIVVTSVVGNVVVMWIILAHKRMR 64
Query: 87 TVTNYFIVNLSLADVLVTITCLPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLS 146
TVTNYF+VNL+ A+ + + W++G CK + +V S+ +++
Sbjct: 65 TVTNYFLVNLAFAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMT 124
Query: 147 CIALDRWYAICHPLMFKSTAKRARNSIVIIWIVSCIIMIPQAIVMECSTVFPGLANKTTL 206
+A DR+ AI HPL + +A + I +IW+++ ++ PQ T+
Sbjct: 125 AVAFDRYMAIIHPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETM--------PS 176
Query: 207 FTVCDERW---GGEIYPKMYHICFFLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQ 263
VC W +IY K+YHIC ++ Y PL ++ AY + LW +IPG SS
Sbjct: 177 RVVCMIEWPEHPNKIYEKVYHICVTVLIYFLPLLVIGYAYTVVGITLWASEIPGDSSDRY 236
Query: 264 RKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARRKTARMLMIVLLVFAICYLPISIL 323
+Q+ A+RK +M+++V+ FAIC+LP I
Sbjct: 237 H-----------------------------EQVSAKRKVVKMMIVVVCTFAICWLPFHIF 267
Query: 324 NVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAANPIIYNFLSGK 370
+L + + + VY WL +++ NPIIY L+ +
Sbjct: 268 FLLPYINPDLYLKKFIQQVYLAIM---WLAMSSTMYNPIIYCCLNDR 311
>gi|62865887 G protein-coupled receptor 54 [Homo sapiens]
Length = 398
Score = 138 bits (347), Expect = 1e-32
Identities = 92/332 (27%), Positives = 153/332 (46%), Gaps = 39/332 (11%)
Query: 55 WVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVV 114
W++ + + ++ L+GN LV + ++ MRTVTN++I NL+ DV + C+P T ++
Sbjct: 43 WLVPLFFAALMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTFLLCCVPFTALL 102
Query: 115 DITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPL--MFKSTAKRARNS 172
W G +CK + Y+Q VSV + TL+ +++DRWY PL + + T + A
Sbjct: 103 YPLPGWVLGDFMCKFVNYIQQVSVQATCATLTAMSVDRWYVTVFPLRALHRRTPRLALAV 162
Query: 173 IVIIWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTY 232
+ IW+ S + P V+ + PG C E + + + + L Y
Sbjct: 163 SLSIWVGSAAVSAP---VLALHRLSPGPR------AYCSEAFPSRALERAFALYNLLALY 213
Query: 233 MAPL---CLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAV 289
+ PL C A L+ ++ R P S++ GQ R AV
Sbjct: 214 LLPLLATCACYAAMLRHLGRVAVRPAPADSAL----------------QGQVLAERAGAV 257
Query: 290 AAEIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFS 349
R K +R++ V+L+FA C+ PI + VL+ + + YA T++
Sbjct: 258 ---------RAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYAAYALKTWA 308
Query: 350 HWLVYANSAANPIIYNFLSGKFREEFKAAFSC 381
H + Y+NSA NP++Y FL FR+ F+ C
Sbjct: 309 HCMSYSNSALNPLLYAFLGSHFRQAFRRVCPC 340
>gi|4557265 beta-1-adrenergic receptor [Homo sapiens]
Length = 477
Score = 137 bits (346), Expect = 2e-32
Identities = 108/376 (28%), Positives = 174/376 (46%), Gaps = 40/376 (10%)
Query: 50 PKEYEWVLIAGYIIVFVVALI--GNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITC 107
P +W G ++ +V LI GNVLV VA+ K ++T+TN FI++L+ AD+++ +
Sbjct: 52 PLSQQWTAGMGLLMALIVLLIVAGNVLVIVAIAKTPRLQTLTNLFIMSLASADLVMGLLV 111
Query: 108 LPATLVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKS--T 165
+P + + W +G C++ + + V+ S+ TL IALDR+ AI P ++S T
Sbjct: 112 VPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIETLCVIALDRYLAITSPFRYQSLLT 171
Query: 166 AKRARNSIVIIWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHI 225
RAR + +W +S ++ I+M A + D + + + Y I
Sbjct: 172 RARARGLVCTVWAISALVSF-LPILMHWWRAESDEARR----CYNDPKCCDFVTNRAYAI 226
Query: 226 CFFLVTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQR-----------KWKPLQPVSQ 274
+V++ PLC+M YL++FR+ +Q+ S +R P+ +
Sbjct: 227 ASSVVSFYVPLCIMAFVYLRVFREAQ-KQVKKIDSCERRFLGGPARPPSPSPSPVPAPAP 285
Query: 275 PRGPGQPTKSRMSAVAAEIKQIRAR---------RKTARMLMIVLLVFAICYLPISILNV 325
P GP +P + +A A + + R +K + L I++ VF +C+LP + NV
Sbjct: 286 PPGPPRPAAAAATAPLANGRAGKRRPSRLVALREQKALKTLGIIMGVFTLCWLPFFLANV 345
Query: 326 LKRVFGMFAHTEDRETV-YAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCCL 384
+K RE V F F +WL YANSA NPIIY S FR+ F+ C
Sbjct: 346 VKAF--------HRELVPDRLFVFFNWLGYANSAFNPIIY-CRSPDFRKAFQGLLCCARR 396
Query: 385 GVHHRQEDRLTRGRTS 400
R R R S
Sbjct: 397 AARRRHATHGDRPRAS 412
>gi|4503905 galanin receptor 2 [Homo sapiens]
Length = 387
Score = 137 bits (345), Expect = 2e-32
Identities = 102/346 (29%), Positives = 159/346 (45%), Gaps = 52/346 (15%)
Query: 61 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW 120
+ ++F+V +GN LV + + + TN FI+NL +AD+ + C+P + + W
Sbjct: 32 FALIFLVGTVGNTLVLAVLLRGGQAVSTTNLFILNLGVADLCFILCCVPFQATIYTLDGW 91
Query: 121 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKS--TAKRARNSIVIIWI 178
FG LCK + +L +++ S TL+ ++LDR+ AI +PL + T + A +I +IW
Sbjct: 92 VFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWG 151
Query: 179 VSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCL 238
+S + P S LAN TVC W M IC F+ +Y+ P+ +
Sbjct: 152 LSLLFSGPYLSYYRQSQ----LAN----LTVCHPAWSAPRRRAM-DICTFVFSYLLPVLV 202
Query: 239 MVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRA 298
+ L Y + R LW + + PV+ G RA
Sbjct: 203 LGLTYARTLRYLW---------------RAVDPVAAGSGAR-----------------RA 230
Query: 299 RRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSA 358
+RK RM++IV +F +C++P L +L FG F T YA SH + YANS
Sbjct: 231 KRKVTRMILIVAALFCLCWMPHHAL-ILCVWFGQFPLTR---ATYALRILSHLVSYANSC 286
Query: 359 ANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESR 404
NPI+Y +S FR+ F+ C G+ R R + GR +R
Sbjct: 287 VNPIVYALVSKHFRKGFRT----ICAGLLGRAPGRAS-GRVCAAAR 327
>gi|4507681 thyrotropin-releasing hormone receptor [Homo sapiens]
Length = 398
Score = 135 bits (341), Expect = 6e-32
Identities = 90/333 (27%), Positives = 161/333 (48%), Gaps = 21/333 (6%)
Query: 52 EYEWVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPAT 111
EY+ V I +I+ + ++GN++V + V + HMRT TN ++V+L++AD++V +
Sbjct: 23 EYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPN 82
Query: 112 LVVDITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPL--MFKSTAKRA 169
+ I +W +G C I YLQ + ++ S +++ ++R+ AICHP+ F T RA
Sbjct: 83 ITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRA 142
Query: 170 RNSIVIIWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFL 229
+ I+ +W + + + +++ + K + C + Y +Y + F
Sbjct: 143 KKIIIFVWAFTSLYCMLWFFLLDLNI----STYKDAIVISCGYKISRNYYSPIY-LMDFG 197
Query: 230 VTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAV 289
V Y+ P+ L + Y I R L+ IP + WK Q T +R
Sbjct: 198 VFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKN-DSTHQNTNLNVNTSNRCFN- 255
Query: 290 AAEIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWF-TF 348
+ +R++ +ML +V+++FA+ ++P L V+ F + +E WF F
Sbjct: 256 ----STVSSRKQVTKMLAVVVILFALLWMPYRTLVVV----NSFLSSPFQEN---WFLLF 304
Query: 349 SHWLVYANSAANPIIYNFLSGKFREEFKAAFSC 381
+Y NSA NP+IYN +S KFR F+ +C
Sbjct: 305 CRICIYLNSAINPVIYNLMSQKFRAAFRKLCNC 337
>gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens]
Length = 384
Score = 133 bits (335), Expect = 3e-31
Identities = 93/363 (25%), Positives = 170/363 (46%), Gaps = 40/363 (11%)
Query: 55 WVLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVV 114
+ L Y V ++ + GN+ + + + K MR VTN IVNLS +D+LV I CLP T V
Sbjct: 41 FTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSDLLVAIMCLPFTFVY 100
Query: 115 DITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIV 174
+ + W FG+++CK+ P++Q VS++VS+ +L IA++R I +P ++ + A I
Sbjct: 101 TLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPRGWRPNNRHAYVGIA 160
Query: 175 IIWIVSCIIMIPQAIVMECSTVFPGLANKTTLFT-----VCDERWGGEIYPKMYHICFFL 229
+IW+++ +P ++ + T P TL VC +++ + + Y +
Sbjct: 161 VIWVLAVASSLP-FLIYQVMTDEP--FQNVTLDAYKDKYVCFDQFPSDSHRLSYTTLLLV 217
Query: 230 VTYMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAV 289
+ Y PLC + + Y +I+ +L R ++++ + + K R S
Sbjct: 218 LQYFGPLCFIFICYFKIYIRLKRR-----NNMMDKM--------------RDNKYRSS-- 256
Query: 290 AAEIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFS 349
E K+I ML+ +++ FA+C+LP++I N + T + + F
Sbjct: 257 --ETKRINI------MLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLL---FLLC 305
Query: 350 HWLVYANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTT 409
H ++ NPI Y FL+ F+ + + F+ C + + T+ K+
Sbjct: 306 HLTAMISTCVNPIFYGFLNKNFQRDLQFFFNFCDFRSRDDDYETIAMSTMHTDVSKTSLK 365
Query: 410 QIS 412
Q S
Sbjct: 366 QAS 368
>gi|161484640 neuromedin B receptor [Homo sapiens]
Length = 390
Score = 130 bits (328), Expect = 2e-30
Identities = 91/328 (27%), Positives = 159/328 (48%), Gaps = 43/328 (13%)
Query: 61 YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW 120
Y+++ V L+GN+++ N MR+V N FI NL+ D+L+ +TC+P + W
Sbjct: 50 YLLIITVGLLGNIMLVKIFITNSAMRSVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEW 109
Query: 121 FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSI--VIIWI 178
FG+ CK+IP +Q SV VSV TL+ ++ DR+ AI +P+ +++ R + + IW+
Sbjct: 110 MFGKVGCKLIPVIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGALLRTCVKAMGIWV 169
Query: 179 VSCIIMIPQAIVMECSTVFPGLANKTTLFTVC-DERWGGEIYPKMYHICFFLVTYMAPLC 237
VS ++ +P+A+ E + + L N + FT C E++PK++ + FLV ++ PL
Sbjct: 170 VSVLLAVPEAVFSEVARI-SSLDNSS--FTACIPYPQTDELHPKIHSVLIFLVYFLIPLA 226
Query: 238 LMVLAYLQIFRKL--WCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQ 295
++ + Y I + L +PG + + TK KQ
Sbjct: 227 IISIYYYHIAKTLIKSAHNLPGEYN-------------------EHTK----------KQ 257
Query: 296 IRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTE-DRETVYAWFTF-SHWLV 353
+ R++ A+++++ + F C+ P IL ++ F + E D + T + L
Sbjct: 258 METRKRLAKIVLVFVGCFIFCWFPNHIL----YMYRSFNYNEIDPSLGHMIVTLVARVLS 313
Query: 354 YANSAANPIIYNFLSGKFREEFKAAFSC 381
+ NS NP LS FR F + C
Sbjct: 314 FGNSCVNPFALYLLSESFRRHFNSQLCC 341
>gi|39725940 opioid receptor, kappa 1 [Homo sapiens]
Length = 380
Score = 129 bits (324), Expect = 5e-30
Identities = 98/354 (27%), Positives = 165/354 (46%), Gaps = 71/354 (20%)
Query: 56 VLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVD 115
++ A Y +VFVV L+GN LV + + M+T TN +I NL+LAD LVT T +P V
Sbjct: 61 IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVT-TTMPFQSTVY 119
Query: 116 ITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPL--MFKSTAKRARNSI 173
+ +W FG LCK++ + ++ S+ TL+ +++DR+ A+CHP+ + T +A+
Sbjct: 120 LMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIIN 179
Query: 174 VIIWIVSCIIMIPQAI-----------VMECSTVFPGLANKTTLFTVCDERWGGEIYPKM 222
+ IW++S + I + V+ECS FP D+ +++ K
Sbjct: 180 ICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPD-----------DDYSWWDLFMK- 227
Query: 223 YHICFFLVTYMAPLCLMVLAY-LQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQP 281
IC F+ ++ P+ ++++ Y L I R R + G+
Sbjct: 228 --ICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSR---------------------- 263
Query: 282 TKSRMSAVAAEIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRET 341
++ R R+ R++++V+ VF +C+ PI I +L G +H+
Sbjct: 264 ------------EKDRNLRRITRLVLVVVAVFVVCWTPIHIF-ILVEALGSTSHS---TA 307
Query: 342 VYAWFTFSHWLVYANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLT 395
+ + F L Y NS+ NPI+Y FL E FK F C + R E + T
Sbjct: 308 ALSSYYFCIALGYTNSSLNPILYAFLD----ENFKRCFRDFCFPLKMRMERQST 357
>gi|21426829 prokineticin receptor 2 [Homo sapiens]
Length = 384
Score = 126 bits (317), Expect = 3e-29
Identities = 99/377 (26%), Positives = 170/377 (45%), Gaps = 58/377 (15%)
Query: 11 PCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAGYIIVFVVALI 70
P ++ +S+ N + + P D +DE+ + R + K + +AG + +V I
Sbjct: 16 PPQDHASSLSFNFSYGDYDLPMD-EDEDMTKT--RTFFAAKIVIGIALAG---IMLVCGI 69
Query: 71 GNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITE--TWFFGQSLCK 128
GN + A+ + +R +TN I NL+++D LV I C P + + +W G LC
Sbjct: 70 GNFVFIAALTRYKKLRNLTNLLIANLAISDFLVAIICCPFEMDYYVVRQLSWEHGHVLCA 129
Query: 129 VIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVSCIIMIPQA 188
+ YL+TVS+ VS L IA+DR+ AI HPL + + A I ++W+VS +I IP A
Sbjct: 130 SVNYLRTVSLYVSTNALLAIAIDRYLAIVHPLKPRMNYQTASFLIALVWMVSILIAIPSA 189
Query: 189 IVMECSTVFPGLANKTTLFTV-------CDERW--GGEIYPKMYHICFFLVTYMAPLCLM 239
A +T LF V C + W ++Y K Y + F V ++ P+ M
Sbjct: 190 Y----------FATETVLFIVKSQEKIFCGQIWPVDQQLYYKSYFLFIFGVEFVGPVVTM 239
Query: 240 VLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRAR 299
L Y +I R+LW + +PG + R K++R R
Sbjct: 240 TLCYARISRELWFKAVPGFQTEQIR-----------------------------KRLRCR 270
Query: 300 RKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAA 359
RKT +LM +L + +C+ P +++ F +++ + A++ + +NS
Sbjct: 271 RKTVLVLMCILTAYVLCWAPFYGFTIVRDFFPT-VFVKEKHYLTAFYVV-ECIAMSNSMI 328
Query: 360 NPIIYNFLSGKFREEFK 376
N + + + + FK
Sbjct: 329 NTVCFVTVKNNTMKYFK 345
>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
Length = 428
Score = 126 bits (316), Expect = 5e-29
Identities = 102/389 (26%), Positives = 177/389 (45%), Gaps = 36/389 (9%)
Query: 56 VLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTV-TNYFIVNLSLADVLVTITCLPATLVV 114
VL+ V ++A++GN+LV VAV + +R + TNYFIV+L+ AD+LV++ +P +
Sbjct: 21 VLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIE 80
Query: 115 DITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAI-CHPLMFKSTAKRARNSI 173
+ + W +G+ C V L + + S+ L CI+LDR+YAI C PL++++ R ++
Sbjct: 81 LVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIAL 140
Query: 174 VI--IWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVT 231
++ W++ I + + L K + + + K Y I +V
Sbjct: 141 MLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVA 200
Query: 232 YMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAA 291
+ P LMVLAY +I+ + ++ ++QR + S+P+ Q + RM
Sbjct: 201 FYIPFLLMVLAYYRIY--VTAKEHAHQIQMLQRAGASSE--SRPQSADQHSTHRM----- 251
Query: 292 EIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHW 351
R K A+ L I++ F +C+ P + N++ + W F W
Sbjct: 252 -----RTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQ------VWTAFL-W 299
Query: 352 LVYANSAANPIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQI 411
L Y NS NP +Y FL+ FR F C ++R R ++ TT I
Sbjct: 300 LGYINSGLNPFLYAFLNKSFRRAFLIILCC--------DDERYRRPSILGQTVPCSTTTI 351
Query: 412 SNFDNISK---LSEQVVLTSISTLPAANG 437
+ ++ + L ++ +L T PA G
Sbjct: 352 NGSTHVLRTDFLFDRDILARYWTKPARAG 380
>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
Length = 359
Score = 125 bits (313), Expect = 1e-28
Identities = 91/330 (27%), Positives = 155/330 (46%), Gaps = 25/330 (7%)
Query: 56 VLIAGYIIVFVVALIGNVLVCVAVWKNHHMRTV-TNYFIVNLSLADVLVTITCLPATLVV 114
VL+ V ++A++GN+LV VAV + +R + TNYFIV+L+ AD+LV++ +P +
Sbjct: 21 VLLTFLSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIE 80
Query: 115 DITETWFFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAI-CHPLMFKSTAKRARNSI 173
+ + W +G+ C V L + + S+ L CI+LDR+YAI C PL++++ R ++
Sbjct: 81 LVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIAL 140
Query: 174 VI--IWIVSCIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVT 231
++ W++ I + + L K + + + K Y I +V
Sbjct: 141 MLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVA 200
Query: 232 YMAPLCLMVLAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAA 291
+ P LMVLAY +I+ + ++ ++QR + S+P+ Q + RM
Sbjct: 201 FYIPFLLMVLAYYRIY--VTAKEHAHQIQMLQRAGASSE--SRPQSADQHSTHRM----- 251
Query: 292 EIKQIRARRKTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHW 351
R K A+ L I++ F +C+ P + N++ + W F W
Sbjct: 252 -----RTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQ------VWTAFL-W 299
Query: 352 LVYANSAANPIIYNFLSGKFREEFKAAFSC 381
L Y NS NP +Y FL+ FR F C
Sbjct: 300 LGYINSGLNPFLYAFLNKSFRRAFLIILCC 329
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.137 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,392,631
Number of Sequences: 37866
Number of extensions: 667068
Number of successful extensions: 4129
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 593
Number of HSP's successfully gapped in prelim test: 178
Number of HSP's that attempted gapping in prelim test: 2452
Number of HSP's gapped (non-prelim): 1080
length of query: 444
length of database: 18,247,518
effective HSP length: 105
effective length of query: 339
effective length of database: 14,271,588
effective search space: 4838068332
effective search space used: 4838068332
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.