Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 221316711
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221316711 piwi-like 4 [Homo sapiens]
(852 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221316711 piwi-like 4 [Homo sapiens] 1710 0.0
gi|66346725 piwi-like 1 [Homo sapiens] 836 0.0
gi|153792298 piwi-like 3 [Homo sapiens] 637 0.0
gi|209180418 piwi-like 2 [Homo sapiens] 566 e-161
gi|24431985 piwi-like 2 [Homo sapiens] 566 e-161
gi|169217928 PREDICTED: similar to piwi like homolog 2 [Homo sap... 182 1e-45
gi|6912352 eukaryotic translation initiation factor 2C, 1 [Homo ... 172 2e-42
gi|29171734 eukaryotic translation initiation factor 2C, 2 [Homo... 168 2e-41
gi|29294647 eukaryotic translation initiation factor 2C, 3 isofo... 165 2e-40
gi|29029593 eukaryotic translation initiation factor 2C, 4 [Homo... 154 3e-37
gi|29337286 eukaryotic translation initiation factor 2C, 3 isofo... 145 2e-34
gi|108773801 glycine dehydrogenase (decarboxylating) [Homo sapiens] 35 0.29
gi|29294649 dicer1 [Homo sapiens] 34 0.66
gi|29294651 dicer1 [Homo sapiens] 34 0.66
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 31 4.3
>gi|221316711 piwi-like 4 [Homo sapiens]
Length = 852
Score = 1710 bits (4428), Expect = 0.0
Identities = 852/852 (100%), Positives = 852/852 (100%)
Query: 1 MSGRARVKARGIARSPSATEVGRIQASPLPRSVDLSNNEASSSNGFLGTSRISTNDKYGI 60
MSGRARVKARGIARSPSATEVGRIQASPLPRSVDLSNNEASSSNGFLGTSRISTNDKYGI
Sbjct: 1 MSGRARVKARGIARSPSATEVGRIQASPLPRSVDLSNNEASSSNGFLGTSRISTNDKYGI 60
Query: 61 SSGDAGSTFMERGVKNKQDFMDLSICTREKLAHVRNCKTGSSGIPVKLVTNLFNLDFPQD 120
SSGDAGSTFMERGVKNKQDFMDLSICTREKLAHVRNCKTGSSGIPVKLVTNLFNLDFPQD
Sbjct: 61 SSGDAGSTFMERGVKNKQDFMDLSICTREKLAHVRNCKTGSSGIPVKLVTNLFNLDFPQD 120
Query: 121 WQLYQYHVTYIPDLASRRLRIALLYSHSELSNKAKAFDGAILFLSQKLEEKVTELSSETQ 180
WQLYQYHVTYIPDLASRRLRIALLYSHSELSNKAKAFDGAILFLSQKLEEKVTELSSETQ
Sbjct: 121 WQLYQYHVTYIPDLASRRLRIALLYSHSELSNKAKAFDGAILFLSQKLEEKVTELSSETQ 180
Query: 181 RGETIKMTITLKRELPSSSPVCIQVFNIIFRKILKKLSMYQIGRNFYNPSEPMEIPQHKL 240
RGETIKMTITLKRELPSSSPVCIQVFNIIFRKILKKLSMYQIGRNFYNPSEPMEIPQHKL
Sbjct: 181 RGETIKMTITLKRELPSSSPVCIQVFNIIFRKILKKLSMYQIGRNFYNPSEPMEIPQHKL 240
Query: 241 SLWPGFAISVSYFERKLLFSADVSYKVLRNETVLEFMTALCQRTGLSCFTQTCEKQLIGL 300
SLWPGFAISVSYFERKLLFSADVSYKVLRNETVLEFMTALCQRTGLSCFTQTCEKQLIGL
Sbjct: 241 SLWPGFAISVSYFERKLLFSADVSYKVLRNETVLEFMTALCQRTGLSCFTQTCEKQLIGL 300
Query: 301 IVLTRYNNRTYSIDDIDWSVKPTHTFQKRDGTEITYVDYYKQQYDITVSDLNQPMLVSLL 360
IVLTRYNNRTYSIDDIDWSVKPTHTFQKRDGTEITYVDYYKQQYDITVSDLNQPMLVSLL
Sbjct: 301 IVLTRYNNRTYSIDDIDWSVKPTHTFQKRDGTEITYVDYYKQQYDITVSDLNQPMLVSLL 360
Query: 361 KKKRNDNSEAQLAHLIPELCFLTGLTDQATSDFQLMKAVAEKTRLSPSGRQQRLARLVDN 420
KKKRNDNSEAQLAHLIPELCFLTGLTDQATSDFQLMKAVAEKTRLSPSGRQQRLARLVDN
Sbjct: 361 KKKRNDNSEAQLAHLIPELCFLTGLTDQATSDFQLMKAVAEKTRLSPSGRQQRLARLVDN 420
Query: 421 IQRNTNARFELETWGLHFGSQISLTGRIVPSEKILMQDHICQPVSAADWSKDIRTCKILN 480
IQRNTNARFELETWGLHFGSQISLTGRIVPSEKILMQDHICQPVSAADWSKDIRTCKILN
Sbjct: 421 IQRNTNARFELETWGLHFGSQISLTGRIVPSEKILMQDHICQPVSAADWSKDIRTCKILN 480
Query: 481 AQSLNTWLILCSDRTEYVAESFLNCLRRVAGSMGFNVDYPKIIKVQENPAAFVRAIQQYV 540
AQSLNTWLILCSDRTEYVAESFLNCLRRVAGSMGFNVDYPKIIKVQENPAAFVRAIQQYV
Sbjct: 481 AQSLNTWLILCSDRTEYVAESFLNCLRRVAGSMGFNVDYPKIIKVQENPAAFVRAIQQYV 540
Query: 541 DPDVQLVMCILPSNQKTYYDSIKKYLSSDCPVPSQCVLARTLNKQGMMMSIATKIAMQMT 600
DPDVQLVMCILPSNQKTYYDSIKKYLSSDCPVPSQCVLARTLNKQGMMMSIATKIAMQMT
Sbjct: 541 DPDVQLVMCILPSNQKTYYDSIKKYLSSDCPVPSQCVLARTLNKQGMMMSIATKIAMQMT 600
Query: 601 CKLGGELWAVEIPLKSLMVVGIDVCKDALSKDVMVVGCVASVNPRITRWFSRCILQRTMT 660
CKLGGELWAVEIPLKSLMVVGIDVCKDALSKDVMVVGCVASVNPRITRWFSRCILQRTMT
Sbjct: 601 CKLGGELWAVEIPLKSLMVVGIDVCKDALSKDVMVVGCVASVNPRITRWFSRCILQRTMT 660
Query: 661 DVADCLKVFMTGALNKWYKYNHDLPARIIVYRAGVGDGQLKTLIEYEVPQLLSSVAESSS 720
DVADCLKVFMTGALNKWYKYNHDLPARIIVYRAGVGDGQLKTLIEYEVPQLLSSVAESSS
Sbjct: 661 DVADCLKVFMTGALNKWYKYNHDLPARIIVYRAGVGDGQLKTLIEYEVPQLLSSVAESSS 720
Query: 721 NTSSRLSVIVVRKKCMPRFFTEMNRTVQNPPLGTVVDSEATRNEWYDFYLISQVACRGTV 780
NTSSRLSVIVVRKKCMPRFFTEMNRTVQNPPLGTVVDSEATRNEWYDFYLISQVACRGTV
Sbjct: 721 NTSSRLSVIVVRKKCMPRFFTEMNRTVQNPPLGTVVDSEATRNEWYDFYLISQVACRGTV 780
Query: 781 SPTYYNVIYDDNGLKPDHMQRLTFKLCHLYYNWPGIVSVPAPCQYAHKLTFLVAQSIHKE 840
SPTYYNVIYDDNGLKPDHMQRLTFKLCHLYYNWPGIVSVPAPCQYAHKLTFLVAQSIHKE
Sbjct: 781 SPTYYNVIYDDNGLKPDHMQRLTFKLCHLYYNWPGIVSVPAPCQYAHKLTFLVAQSIHKE 840
Query: 841 PSLELANHLFYL 852
PSLELANHLFYL
Sbjct: 841 PSLELANHLFYL 852
>gi|66346725 piwi-like 1 [Homo sapiens]
Length = 861
Score = 836 bits (2159), Expect = 0.0
Identities = 424/864 (49%), Positives = 582/864 (67%), Gaps = 15/864 (1%)
Query: 1 MSGRARVKARGIAR---------SPSATEVGRIQASPLPRSVDLSNNEASSSNGFLGTSR 51
M+GRAR +ARG AR S ++ + G IQ P P + G G +
Sbjct: 1 MTGRARARARGRARGQETAQLVGSTASQQPGYIQPRPQPPPAEGELFGRGRQRGTAGGTA 60
Query: 52 ISTNDKYGISSGDAGSTFMERGVKNKQDFMDLSICTREKLAHVRNCKTGSSGIPVKLVTN 111
S + IS+G + ERG + ++DF DL + TR+ L HV+ KTGSSGI V+L TN
Sbjct: 61 KSQGLQ--ISAGFQELSLAERGGR-RRDFHDLGVNTRQNLDHVKESKTGSSGIIVRLSTN 117
Query: 112 LFNLDFPQDWQLYQYHVTYIPDLASRRLRIALLYSHSELSNKAKAFDGAILFLSQKLEEK 171
F L W LYQYH+ Y P + +RRLR ALL+ H +L K AFDG ILFL ++L++K
Sbjct: 118 HFRLTSRPQWALYQYHIDYNPLMEARRLRSALLFQHEDLIGKCHAFDGTILFLPKRLQQK 177
Query: 172 VTELSSETQRGETIKMTITLKRELPSSSPVCIQVFNIIFRKILKKLSMYQIGRNFYNPSE 231
VTE+ S+T+ GE +++TITL ELP +SP C+Q +NIIFR++LK +++ QIGRN+YNP++
Sbjct: 178 VTEVFSKTRNGEDVRITITLTNELPPTSPTCLQFYNIIFRRLLKIMNLQQIGRNYYNPND 237
Query: 232 PMEIPQHKLSLWPGFAISVSYFERKLLFSADVSYKVLRNETVLEFMTALCQRTGLSCFTQ 291
P++IP H+L +WPGF S+ +E ++ DVS+KVLR+ETVL+FM +T F +
Sbjct: 238 PIDIPSHRLVIWPGFTTSILQYENSIMLCTDVSHKVLRSETVLDFMFNFYHQTEEHKFQE 297
Query: 292 TCEKQLIGLIVLTRYNNRTYSIDDIDWSVKPTHTFQKRDGTEITYVDYYKQQYDITVSDL 351
K+LIGL+VLT+YNN+TY +DDIDW P TF+K DG+E+++++YY++QY+ ++DL
Sbjct: 298 QVSKELIGLVVLTKYNNKTYRVDDIDWDQNPKSTFKKADGSEVSFLEYYRKQYNQEITDL 357
Query: 352 NQPMLVSLLKKKRNDNSEAQ-LAHLIPELCFLTGLTDQATSDFQLMKAVAEKTRLSPSGR 410
QP+LVS K++R A LIPELC+LTGLTD+ +DF +MK +A TRL+P R
Sbjct: 358 KQPVLVSQPKRRRGPGGTLPGPAMLIPELCYLTGLTDKMRNDFNVMKDLAVHTRLTPEQR 417
Query: 411 QQRLARLVDNIQRNTNARFELETWGLHFGSQI-SLTGRIVPSEKILMQDHICQ-PVSAAD 468
Q+ + RL+D I +N N + EL WGL F S + S +GRI+ +EKI AD
Sbjct: 418 QREVGRLIDYIHKNDNVQRELRDWGLSFDSNLLSFSGRILQTEKIHQGGKTFDYNPQFAD 477
Query: 469 WSKDIRTCKILNAQSLNTWLILCSDRTEYVAESFLNCLRRVAGSMGFNVDYPKIIKVQEN 528
WSK+ R +++ + L+ WL++ + R A S + L +V +MG + +I+V +
Sbjct: 478 WSKETRGAPLISVKPLDNWLLIYTRRNYEAANSLIQNLFKVTPAMGMQMRKAIMIEVDDR 537
Query: 529 PAAFVRAIQQYVDPDVQLVMCILPSNQKTYYDSIKKYLSSDCPVPSQCVLARTLNKQGMM 588
A++R +QQ V D Q+V+C+L SN+K YD+IKKYL +DCP PSQCV+ARTL KQ +
Sbjct: 538 TEAYLRVLQQKVTADTQIVVCLLSSNRKDKYDAIKKYLCTDCPTPSQCVVARTLGKQQTV 597
Query: 589 MSIATKIAMQMTCKLGGELWAVEIPLKSLMVVGIDVCKDALSKDVMVVGCVASVNPRITR 648
M+IATKIA+QM CK+GGELW V+IPLK +M+VGID D + + G VAS+N +TR
Sbjct: 598 MAIATKIALQMNCKMGGELWRVDIPLKLVMIVGIDCYHDMTAGRRSIAGFVASINEGMTR 657
Query: 649 WFSRCILQRTMTDVADCLKVFMTGALNKWYKYNHDLPARIIVYRAGVGDGQLKTLIEYEV 708
WFSRCI Q ++ D LKV + AL W N +P+RIIVYR GVGDGQLKTL+ YEV
Sbjct: 658 WFSRCIFQDRGQELVDGLKVCLQAALRAWNSCNEYMPSRIIVYRDGVGDGQLKTLVNYEV 717
Query: 709 PQLLSSVAESSSNTSSRLSVIVVRKKCMPRFFTEMNRTVQNPPLGTVVDSEATRNEWYDF 768
PQ L + + RL+VIVV+K+ RFF + +QNP GTV+D E TR EWYDF
Sbjct: 718 PQFLDCLKSIGRGYNPRLTVIVVKKRVNTRFFAQSGGRLQNPLPGTVIDVEVTRPEWYDF 777
Query: 769 YLISQVACRGTVSPTYYNVIYDDNGLKPDHMQRLTFKLCHLYYNWPGIVSVPAPCQYAHK 828
+++SQ G+VSPT+YNVIYD++GLKPDH+QRLT+KLCH+YYNWPG++ VPAPCQYAHK
Sbjct: 778 FIVSQAVRSGSVSPTHYNVIYDNSGLKPDHIQRLTYKLCHIYYNWPGVIRVPAPCQYAHK 837
Query: 829 LTFLVAQSIHKEPSLELANHLFYL 852
L FLV QSIH+EP+L L+N L+YL
Sbjct: 838 LAFLVGQSIHREPNLSLSNRLYYL 861
>gi|153792298 piwi-like 3 [Homo sapiens]
Length = 882
Score = 637 bits (1643), Expect = 0.0
Identities = 345/886 (38%), Positives = 519/886 (58%), Gaps = 38/886 (4%)
Query: 1 MSGRARVKARGIAR-----------------SPSATEVGRIQASPLPRSVDLSN----NE 39
M GRAR +ARG AR S + E ++Q++P P ++
Sbjct: 1 MPGRARTRARGRARRRESYQQEAPGGPRAPGSATTQEPPQLQSTPRPLQEEVPVVRPLQP 60
Query: 40 ASSSNGFLGTSRISTNDKYGISSGDAGSTFMERGVKNKQDFMDLSICTREKLAHVRNCKT 99
++ G G ++ + G +G + ER + F DL + TR+ + HV++ KT
Sbjct: 61 RAARGGAGGGAQSQGVKEPGPEAGLHTAPLQERRIGGV--FQDLVVNTRQDMKHVKDSKT 118
Query: 100 GSSGIPVKLVTNLFNLDFPQDWQLYQYHVTYIPDLASRRLRIALLYSHSELSNKAKAFDG 159
GS G V+L+ N F + W Y+Y+V Y PD+ LR LL H + FDG
Sbjct: 119 GSEGTVVQLLANHFRVISRPQWVAYKYNVDYKPDIEDGNLRTILLDQHRRKFGERHIFDG 178
Query: 160 AILFLSQKLEEKVTELSSETQRGETIKMTITLKRELPSSSPVCIQVFNIIFRKILKKLSM 219
L LS+ L+E+ E S T+ +K+T+ +EL +SP C++ +NI+FR+ K L
Sbjct: 179 NSLLLSRPLKERRVEWLSTTKDKNIVKITVEFSKELTPTSPDCLRYYNILFRRTFKLLDF 238
Query: 220 YQIGRNFYNPSEPMEIPQH--KLSLWPGFAISVSYFERKLLFSADVSYKVLRNETVLEFM 277
Q+GRN+Y + +++ +H L +W G+ SV +E + ADVS+K+LR ET +F+
Sbjct: 239 EQVGRNYYTKKKAIQLYRHGTSLEIWLGYVTSVLQYENSITLCADVSHKLLRIETAYDFI 298
Query: 278 TALCQRTGLSCFTQTCEKQLIGLIVLTRYNNRTYSIDDIDWSVKPTHTFQKRDGTEITYV 337
+ + +LIG IVLT+YNN+TY +DDIDW P TF K DG++ITY+
Sbjct: 299 KRTSAQAQTGNIREEVTNKLIGSIVLTKYNNKTYRVDDIDWKQNPEDTFNKSDGSKITYI 358
Query: 338 DYYKQQYDITVSDLNQPMLVSLLK-KKRNDNSEAQLAHLIPELCFLTGLTDQATSDFQLM 396
DYY+QQ+ V+ QP+LVS + KK ++ + LIP+LC +TGLTD+ D+ ++
Sbjct: 359 DYYRQQHKEIVTVKKQPLLVSQGRWKKGLTGTQREPILLIPQLCHMTGLTDEICKDYSIV 418
Query: 397 KAVAEKTRLSPSGRQQRLARLVDNIQRNTNARFELETWGLHFGSQ-ISLTGRIVPSEKIL 455
K +A+ TRLSP R L ++ +Q N R L+ W L F + +S+ GR++ + I+
Sbjct: 419 KELAKHTRLSPRRRHHTLKEFINTLQDNKKVRELLQLWDLKFDTNFLSVPGRVLKNANIV 478
Query: 456 MQDHICQPVSAADWSKDIRTCKILNAQSLNTWLILCSDRTEYVAESFLNCLRRVAGSMGF 515
+ + S DWS++IR +LNA L++WLIL S + A S L+ V MG
Sbjct: 479 QGRRMVKANSQGDWSREIRELPLLNAMPLHSWLILYSRSSHREAMSLKGHLQSVTAPMGI 538
Query: 516 NVDYPKIIKVQENPAAFVRAIQQYVDPDVQL---------VMCILPSNQKTYYDSIKKYL 566
+ ++I+V + +++ +++Y P +Q+ V+CILP++ K YDSIK+YL
Sbjct: 539 TMKPAEMIEVDGDANSYIDTLRKYTRPTLQMGMSCLLVFKVICILPNDDKRRYDSIKRYL 598
Query: 567 SSDCPVPSQCVLARTLNKQGMMMSIATKIAMQMTCKLGGELWAVEIPLKSLMVVGIDVCK 626
+ CP+PSQCV+ +TL K +I TKIA QM CK+GG LW VE ++ M VGID
Sbjct: 599 CTKCPIPSQCVVKKTLEKV-QARTIVTKIAQQMNCKMGGALWKVETDVQRTMFVGIDCFH 657
Query: 627 DALSKDVMVVGCVASVNPRITRWFSRCILQRTMTDVADCLKVFMTGALNKWYKYNHDLPA 686
D +++ + G VAS N +T+W+S+C++Q+T ++ L++ + AL+ W K +P
Sbjct: 658 DIVNRQKSIAGFVASTNAELTKWYSQCVIQKTGEELVKELEICLKAALDVWCKNESSMPH 717
Query: 687 RIIVYRAGVGDGQLKTLIEYEVPQLLSSVAESSSNTSSRLSVIVVRKKCMPRFFTEMNRT 746
+IVYR GVGDGQL+ L+++E ++ S+ ++ S + L+ IVV+K+ RFF +
Sbjct: 718 SVIVYRDGVGDGQLQALLDHEAKKM-STYLKTISPNNFTLAFIVVKKRINTRFFLKHGSN 776
Query: 747 VQNPPLGTVVDSEATRNEWYDFYLISQVACRGTVSPTYYNVIYDDNGLKPDHMQRLTFKL 806
QNPP GTV+D E TRNEWYDF+++SQ GTV+PT+YNVIYD GL PD +QRLT+ L
Sbjct: 777 FQNPPPGTVIDVELTRNEWYDFFIVSQSVQDGTVTPTHYNVIYDTIGLSPDTVQRLTYCL 836
Query: 807 CHLYYNWPGIVSVPAPCQYAHKLTFLVAQSIHKEPSLELANHLFYL 852
CH+YYN PGI+ VPAPC YAHKL +LV QSIH+EP+ L+ LFYL
Sbjct: 837 CHMYYNLPGIIRVPAPCHYAHKLAYLVGQSIHQEPNRSLSTRLFYL 882
>gi|209180418 piwi-like 2 [Homo sapiens]
Length = 973
Score = 566 bits (1458), Expect = e-161
Identities = 300/763 (39%), Positives = 449/763 (58%), Gaps = 13/763 (1%)
Query: 98 KTGSSGIPVKLVTNLFNLDFPQDWQLYQYHVTYIPDLASRRLRIALLYSHSELSNKAKAF 157
K GS G P L NL + + +YQYHVT+ P++ + +R +L H ++ AF
Sbjct: 216 KQGSKGTPQSLGLNLVKIQCHNE-AVYQYHVTFSPNVECKSMRFGMLKDHQAVTGNVTAF 274
Query: 158 DGAILFLSQKLEEKVTELSSETQRGET-IKMTITLKRELPSSSPVCIQVFNIIFRKILKK 216
DG+IL+L KL++ V EL S+ + I + I + + L S +CI +N++FR+++K
Sbjct: 275 DGSILYLPVKLQQ-VLELKSQRKTDSAEISIKIQMTKILEPCSDLCIPFYNVVFRRVMKL 333
Query: 217 LSMYQIGRNFYNPSEPMEIPQHKLSLWPGFAISVSYFERKLLFSADVSYKVLRNETVLEF 276
L M +GRNFY+P+ M + QH+L +WPG+A S+ + L ADVS+KV+RN+ VL+
Sbjct: 334 LDMKLVGRNFYDPTSAMVLQQHRLQIWPGYAASIRRTDGGLFLLADVSHKVIRNDCVLDV 393
Query: 277 MTALCQRTGLSCFTQTCEKQLIGLIVLTRYNNRTYSIDDIDWSVKPTHTFQKRDGTEITY 336
M A+ Q+ F C K L+G IV+TRYNNRTY IDD+DW+ P +F DG EIT+
Sbjct: 394 MHAIYQQNK-EHFQDECTKLLVGNIVITRYNNRTYRIDDVDWNKTPKDSFTMSDGKEITF 452
Query: 337 VDYYKQQYDITVSDLNQPMLVSLLKKKRNDNSEAQLAH---LIPELCFLTGLTDQATSDF 393
++YY + Y ITV + +QP+L+ +R DN L L+PEL F+TG+ ++ DF
Sbjct: 453 LEYYSKNYGITVKEEDQPLLIHR-PSERQDNHGMLLKGEILLLPELSFMTGIPEKMKKDF 511
Query: 394 QLMKAVAEKTRLSPSGRQQRLARLVDNIQRNTNARFELETWGLHFGSQI-SLTGRIVPSE 452
+ MK +A++ LSP L L+ I +N A EL WGL + + GR++P E
Sbjct: 512 RAMKDLAQQINLSPKQHHSALECLLQRIAKNEAATNELMRWGLRLQKDVHKIEGRVLPME 571
Query: 453 KILMQDHICQPVSAADWSKDIRTCKILNAQSLNTWLILCSDRTEYVAESFLNCLRRVAGS 512
+I +++ +W K++ + ++ W + R A +N L ++AG
Sbjct: 572 RINLKNTSFITSQELNWVKEVTRDPSILTIPMHFWALFYPKRAMDQARELVNMLEKIAGP 631
Query: 513 MGFNVDYPKIIKVQENPA-AFVRAIQQYVDPD--VQLVMCILPSNQKTYYDSIKKYLSSD 569
+G + P ++++++ +VR IQ + + +Q+V+CI+ + Y +IKK
Sbjct: 632 IGMRMSPPAWVELKDDRIETYVRTIQSTLGAEGKIQMVVCIIMGPRDDLYGAIKKLCCVQ 691
Query: 570 CPVPSQCVLARTLNKQGMMMSIATKIAMQMTCKLGGELWAVEIPLKSLMVVGIDVCKDAL 629
PVPSQ V RT+ + + S+A KI +Q+ CKLGGELW V+IPLK LMV+G+DV D
Sbjct: 692 SPVPSQVVNVRTIGQPTRLRSVAQKILLQINCKLGGELWGVDIPLKQLMVIGMDVYHDPS 751
Query: 630 SKDVMVVGCVASVNPRITRWFSRCILQRTMTDVADCLKVFMTGALNKWYKYNHDLPARII 689
VVG VAS+N +T+W+SR + Q ++ D LK+ + G+L K+Y+ NH LP +I+
Sbjct: 752 RGMRSVVGFVASINLTLTKWYSRVVFQMPHQEIVDSLKLCLVGSLKKFYEVNHCLPEKIV 811
Query: 690 VYRAGVGDGQLKTLIEYEVPQLLSSVAESSSNTSSRLSVIVVRKKCMPRFFTEMNRTVQN 749
VYR GV DGQLKT+ YE+PQ L E+ N ++ V VV+KK + +
Sbjct: 812 VYRDGVSDGQLKTVANYEIPQ-LQKCFEAFENYQPKMVVFVVQKKISTNLYLAAPQNFVT 870
Query: 750 PPLGTVVDSEATRNEWYDFYLISQVACRGTVSPTYYNVIYDDNGLKPDHMQRLTFKLCHL 809
P GTVVD T EW DFYL++ +G PT+Y + + L PDHMQRLTFKLCH+
Sbjct: 871 PTPGTVVDHTITSCEWVDFYLLAHHVRQGCGIPTHYVCVLNTANLSPDHMQRLTFKLCHM 930
Query: 810 YYNWPGIVSVPAPCQYAHKLTFLVAQSIHKEPSLELANHLFYL 852
Y+NWPG + VPAPC+YAHKL FL +H EP+++L +LF+L
Sbjct: 931 YWNWPGTIRVPAPCKYAHKLAFLSGHILHHEPAIQLCENLFFL 973
>gi|24431985 piwi-like 2 [Homo sapiens]
Length = 973
Score = 566 bits (1458), Expect = e-161
Identities = 300/763 (39%), Positives = 449/763 (58%), Gaps = 13/763 (1%)
Query: 98 KTGSSGIPVKLVTNLFNLDFPQDWQLYQYHVTYIPDLASRRLRIALLYSHSELSNKAKAF 157
K GS G P L NL + + +YQYHVT+ P++ + +R +L H ++ AF
Sbjct: 216 KQGSKGTPQSLGLNLVKIQCHNE-AVYQYHVTFSPNVECKSMRFGMLKDHQAVTGNVTAF 274
Query: 158 DGAILFLSQKLEEKVTELSSETQRGET-IKMTITLKRELPSSSPVCIQVFNIIFRKILKK 216
DG+IL+L KL++ V EL S+ + I + I + + L S +CI +N++FR+++K
Sbjct: 275 DGSILYLPVKLQQ-VLELKSQRKTDSAEISIKIQMTKILEPCSDLCIPFYNVVFRRVMKL 333
Query: 217 LSMYQIGRNFYNPSEPMEIPQHKLSLWPGFAISVSYFERKLLFSADVSYKVLRNETVLEF 276
L M +GRNFY+P+ M + QH+L +WPG+A S+ + L ADVS+KV+RN+ VL+
Sbjct: 334 LDMKLVGRNFYDPTSAMVLQQHRLQIWPGYAASIRRTDGGLFLLADVSHKVIRNDCVLDV 393
Query: 277 MTALCQRTGLSCFTQTCEKQLIGLIVLTRYNNRTYSIDDIDWSVKPTHTFQKRDGTEITY 336
M A+ Q+ F C K L+G IV+TRYNNRTY IDD+DW+ P +F DG EIT+
Sbjct: 394 MHAIYQQNK-EHFQDECTKLLVGNIVITRYNNRTYRIDDVDWNKTPKDSFTMSDGKEITF 452
Query: 337 VDYYKQQYDITVSDLNQPMLVSLLKKKRNDNSEAQLAH---LIPELCFLTGLTDQATSDF 393
++YY + Y ITV + +QP+L+ +R DN L L+PEL F+TG+ ++ DF
Sbjct: 453 LEYYSKNYGITVKEEDQPLLIHR-PSERQDNHGMLLKGEILLLPELSFMTGIPEKMKKDF 511
Query: 394 QLMKAVAEKTRLSPSGRQQRLARLVDNIQRNTNARFELETWGLHFGSQI-SLTGRIVPSE 452
+ MK +A++ LSP L L+ I +N A EL WGL + + GR++P E
Sbjct: 512 RAMKDLAQQINLSPKQHHSALECLLQRIAKNEAATNELMRWGLRLQKDVHKIEGRVLPME 571
Query: 453 KILMQDHICQPVSAADWSKDIRTCKILNAQSLNTWLILCSDRTEYVAESFLNCLRRVAGS 512
+I +++ +W K++ + ++ W + R A +N L ++AG
Sbjct: 572 RINLKNTSFITSQELNWVKEVTRDPSILTIPMHFWALFYPKRAMDQARELVNMLEKIAGP 631
Query: 513 MGFNVDYPKIIKVQENPA-AFVRAIQQYVDPD--VQLVMCILPSNQKTYYDSIKKYLSSD 569
+G + P ++++++ +VR IQ + + +Q+V+CI+ + Y +IKK
Sbjct: 632 IGMRMSPPAWVELKDDRIETYVRTIQSTLGAEGKIQMVVCIIMGPRDDLYGAIKKLCCVQ 691
Query: 570 CPVPSQCVLARTLNKQGMMMSIATKIAMQMTCKLGGELWAVEIPLKSLMVVGIDVCKDAL 629
PVPSQ V RT+ + + S+A KI +Q+ CKLGGELW V+IPLK LMV+G+DV D
Sbjct: 692 SPVPSQVVNVRTIGQPTRLRSVAQKILLQINCKLGGELWGVDIPLKQLMVIGMDVYHDPS 751
Query: 630 SKDVMVVGCVASVNPRITRWFSRCILQRTMTDVADCLKVFMTGALNKWYKYNHDLPARII 689
VVG VAS+N +T+W+SR + Q ++ D LK+ + G+L K+Y+ NH LP +I+
Sbjct: 752 RGMRSVVGFVASINLTLTKWYSRVVFQMPHQEIVDSLKLCLVGSLKKFYEVNHCLPEKIV 811
Query: 690 VYRAGVGDGQLKTLIEYEVPQLLSSVAESSSNTSSRLSVIVVRKKCMPRFFTEMNRTVQN 749
VYR GV DGQLKT+ YE+PQ L E+ N ++ V VV+KK + +
Sbjct: 812 VYRDGVSDGQLKTVANYEIPQ-LQKCFEAFENYQPKMVVFVVQKKISTNLYLAAPQNFVT 870
Query: 750 PPLGTVVDSEATRNEWYDFYLISQVACRGTVSPTYYNVIYDDNGLKPDHMQRLTFKLCHL 809
P GTVVD T EW DFYL++ +G PT+Y + + L PDHMQRLTFKLCH+
Sbjct: 871 PTPGTVVDHTITSCEWVDFYLLAHHVRQGCGIPTHYVCVLNTANLSPDHMQRLTFKLCHM 930
Query: 810 YYNWPGIVSVPAPCQYAHKLTFLVAQSIHKEPSLELANHLFYL 852
Y+NWPG + VPAPC+YAHKL FL +H EP+++L +LF+L
Sbjct: 931 YWNWPGTIRVPAPCKYAHKLAFLSGHILHHEPAIQLCENLFFL 973
>gi|169217928 PREDICTED: similar to piwi like homolog 2 [Homo
sapiens]
Length = 349
Score = 182 bits (461), Expect = 1e-45
Identities = 111/339 (32%), Positives = 181/339 (53%), Gaps = 11/339 (3%)
Query: 392 DFQLMKAVAEKTRLSPSGRQQRLARLVDNIQRNTNARFELETWGLHFGSQI-SLTGRIVP 450
DF+ MK +A++ LSP L L+ I +N A EL WGL + + GR++P
Sbjct: 4 DFRAMKDLAQQINLSPKQHHSALECLLQRIAKNEAATNELMRWGLRLQKDVHKIEGRVLP 63
Query: 451 SEKILMQDHICQPVSAADWSKDIRTCKILNAQSLNTWLILCSDRTEYVAESFLNCLRRVA 510
E+I +++ +W K++ + ++ W + R A +N L ++A
Sbjct: 64 MERINLKNTSFITSQELNWVKEVTRDPSILTIPMHFWALFYPKRAMDQARELVNMLEKIA 123
Query: 511 GSMGFNVDYPKIIKVQENPA-AFVRAIQQYVDPD--VQLVMCILPSNQKTYYDSIKKYLS 567
G +G + P ++++++ +VR IQ + + +Q+V+CI+ + Y +IKK
Sbjct: 124 GPIGMRMSPPAWVELKDDRIETYVRTIQSTLGAEGKIQMVVCIIMGPRDDLYGAIKKLCC 183
Query: 568 SDCPVPSQCVLARTLNKQGMMMSIATKIAMQMTCKLGGELWAVEIPLKSLMVVGIDVCKD 627
PVPSQ V RT+ + + S+A KI +Q+ CKLGGELW V+IPLK LMV+G+DV D
Sbjct: 184 VQSPVPSQVVNVRTIGQPTRLRSVAQKILLQINCKLGGELWGVDIPLKQLMVIGMDVYHD 243
Query: 628 ALSKDVMVVGCVASVNPRITRWFSRCILQRTMTDVADCLKVFMTGALNKWYKYNHDLPAR 687
VVG VAS+N +T+W+SR + Q ++ D LK+ + G+L K+Y+ A+
Sbjct: 244 PSRGMRSVVGFVASINLTLTKWYSRVVFQMPHQEIVDSLKLCLVGSLKKFYE-----AAQ 298
Query: 688 IIVYRAGVGDGQLKTLIEYEVPQLLSSVAESSSNTSSRL 726
++A QLK L + ++ +V SSNTS +L
Sbjct: 299 SSSFQASACTDQLKELNAFIWFRM--AVTTGSSNTSEQL 335
>gi|6912352 eukaryotic translation initiation factor 2C, 1 [Homo
sapiens]
Length = 857
Score = 172 bits (435), Expect = 2e-42
Identities = 189/801 (23%), Positives = 347/801 (43%), Gaps = 90/801 (11%)
Query: 100 GSSGIPVKLVTNLFNLDFPQDWQLYQYHVTYIPDLASRRLR---IALLYSHSE---LSNK 153
G+ G P+KL+ N F +D P+ +Y Y V PD RR+ + + H + ++
Sbjct: 30 GTVGKPIKLLANYFEVDIPKI-DVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQIFGDR 88
Query: 154 AKAFDG--------AILFLSQKLEEKVTELSSETQRGETIKMTIT---------LKRELP 196
+DG A+ +++++ +VT R K++I L L
Sbjct: 89 KPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDR--IFKVSIKWLAIVSWRMLHEALV 146
Query: 197 SSS-PV---CIQVFNIIFRKILKKLSMYQIGRNFYNPSEPMEIPQHK-LSLWPGFAISVS 251
S PV +Q ++ R L + +GR+F++P E P +W GF SV
Sbjct: 147 SGQIPVPLESVQALDVAMRH-LASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVR 205
Query: 252 YFERKLLFSADVSYKVL-RNETVLEFMTALCQRTGLSCFTQTCE--------KQLIGLIV 302
K++ + DVS + + V+EFM + + + K++ GL V
Sbjct: 206 PAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKV 265
Query: 303 LTRY---NNRTYSIDDIDWSVKPTHTF----QKRDGTEITYVDYYKQQYDITVSDLNQPM 355
+ R Y + ++ TF + E T Y+KQ+Y++ + + P
Sbjct: 266 EVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPC 325
Query: 356 LVSLLKKKRNDNSEAQLAHLIPELCFLTGLTDQATSDFQLMKAVAEKTRLSPSGRQQRLA 415
L + +++++ ++ +++ + LTD TS ++KA A S RQ+ ++
Sbjct: 326 L-QVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTST--MIKATAR----SAPDRQEEIS 378
Query: 416 RLVDNIQRNTNARFELETWGLHFGSQIS-----LTGRIVPSEKILMQDHICQPVSAADWS 470
RL+ N A + L+ + FG ++ +TGR++P+ + +
Sbjct: 379 RLMKN------ASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGV 432
Query: 471 KDIRTCKILNAQSLNTWLILC----SDRTEYVAESFLNCLRRVAGSMGFNVDYPKIIKVQ 526
D+R + N + W I C E V ++F + LR+++ G +
Sbjct: 433 WDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKY 492
Query: 527 ENPAAFVRAIQQYVD---PDVQLVMCILPSNQKTYYDSIKKYLSSDCPVPSQCVLARTLN 583
A V + +++ +QL++ ILP Y + +K+ + + +QCV + +
Sbjct: 493 AQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAE-VKRVGDTLLGMATQCVQVKNVV 551
Query: 584 KQGMMMSIATKIAMQMTCKLGGELWAVEIP-------LKSLMVVGIDVCKDALS--KDVM 634
K + + +++ KLGG + + +P + ++ +G DV K
Sbjct: 552 KTSPQT--LSNLCLKINVKLGG-INNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPS 608
Query: 635 VVGCVASVNPRITRWFSRCILQRTMTDVADCLKVFMTGALNKWYKYNHDLPARIIVYRAG 694
+ V S++ +R+ + +QR ++ + L + L ++YK P RII YR G
Sbjct: 609 ITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDG 668
Query: 695 VGDGQLKTLIEYEVPQLLSSVAESSSNTSSRLSVIVVRKKCMPRFF-TEMNRTVQ---NP 750
V +GQL ++ YE+ + + + + ++ IVV+K+ R F + N + N
Sbjct: 669 VPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNI 728
Query: 751 PLGTVVDSEATRNEWYDFYLISQVACRGTVSPTYYNVIYDDNGLKPDHMQRLTFKLCHLY 810
P GT VD+ T +DFYL S +GT P++Y V++DDN D +Q LT++LCH Y
Sbjct: 729 PAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTY 788
Query: 811 YNWPGIVSVPAPCQYAHKLTF 831
VS+PAP YA + F
Sbjct: 789 VRCTRSVSIPAPAYYARLVAF 809
>gi|29171734 eukaryotic translation initiation factor 2C, 2 [Homo
sapiens]
Length = 859
Score = 168 bits (425), Expect = 2e-41
Identities = 191/800 (23%), Positives = 344/800 (43%), Gaps = 88/800 (11%)
Query: 100 GSSGIPVKLVTNLFNLDFPQDWQLYQYHVTYIPDLASRRLRIALL------YSHSELSNK 153
G+SG +KL N F +D P+ +Y Y + P+ RR+ ++ + ++
Sbjct: 32 GTSGRTIKLQANFFEMDIPKI-DIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDR 90
Query: 154 AKAFDGAILFLS--------QKLEEKVTELSSETQRGETIKMTI-------------TLK 192
FDG + K+E +VT R K++I L
Sbjct: 91 KPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDR--IFKVSIKWVSCVSLQALHDALS 148
Query: 193 RELPSSSPVCIQVFNIIFRKILKKLSMYQIGRNFYNPSEPMEIPQHK-LSLWPGFAISVS 251
LPS IQ +++ R L + +GR+F+ SE P +W GF SV
Sbjct: 149 GRLPSVPFETIQALDVVMRH-LPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVR 207
Query: 252 YFERKLLFSADVSYKVL-RNETVLEFMTALC--------QRTGLSCFTQTCEKQLIGLIV 302
K++ + DVS + + V+EF+ + Q+ K++ GL V
Sbjct: 208 PSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKV 267
Query: 303 LTRY---NNRTYSIDDIDWSVKPTHTF--QKRDG--TEITYVDYYKQQYDITVSDLNQPM 355
+ R Y + ++ TF Q+ G E T Y+K ++ + + + P
Sbjct: 268 EITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPC 327
Query: 356 LVSLLKKKRNDNSEAQLAHLIPELCFLTGLTDQATSDFQLMKAVAEKTRLSPSGRQQRLA 415
L + +++++ ++ +++ + LTD TS +++A A S RQ+ ++
Sbjct: 328 L-QVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTST--MIRATAR----SAPDRQEEIS 380
Query: 416 RLVDNIQRNTNARFELETWGLHFGSQIS-LTGRIVPSEKILMQDH---ICQPVSAADWSK 471
+L+ + NT+ + +G+ +++ +TGR++ IL I PV W
Sbjct: 381 KLMRSASFNTDPY--VREFGIMVKDEMTDVTGRVLQPPSILYGGRNKAIATPVQGV-W-- 435
Query: 472 DIRTCKILNAQSLNTWLILC----SDRTEYVAESFLNCLRRVAGSMGFNVDYPKIIKVQE 527
D+R + + W I C TE +SF LR+++ G +
Sbjct: 436 DMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYA 495
Query: 528 NPAAFVRAIQQYVD---PDVQLVMCILPSNQKTYYDSIKKYLSSDCPVPSQCVLARTLNK 584
A V + +++ +QLV+ ILP Y + +K+ + + +QCV + N
Sbjct: 496 QGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAE-VKRVGDTVLGMATQCVQMK--NV 552
Query: 585 QGMMMSIATKIAMQMTCKLGGELWAVEIPL-------KSLMVVGIDVCKDALS--KDVMV 635
Q + + +++ KLGG + + +P + ++ +G DV K +
Sbjct: 553 QRTTPQTLSNLCLKINVKLGG-VNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSI 611
Query: 636 VGCVASVNPRITRWFSRCILQRTMTDVADCLKVFMTGALNKWYKYNHDLPARIIVYRAGV 695
V S++ R+ + +Q+ ++ L + L ++YK P RII YR GV
Sbjct: 612 AAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGV 671
Query: 696 GDGQLKTLIEYEVPQLLSSVAESSSNTSSRLSVIVVRKKCMPRFF-TEMNRTVQ---NPP 751
+GQ + ++ +E+ + + + + ++ IVV+K+ R F T+ N V N P
Sbjct: 672 SEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIP 731
Query: 752 LGTVVDSEATRNEWYDFYLISQVACRGTVSPTYYNVIYDDNGLKPDHMQRLTFKLCHLYY 811
GT VD++ T +DFYL S +GT P++Y+V++DDN D +Q LT++LCH Y
Sbjct: 732 AGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYV 791
Query: 812 NWPGIVSVPAPCQYAHKLTF 831
VS+PAP YAH + F
Sbjct: 792 RCTRSVSIPAPAYYAHLVAF 811
>gi|29294647 eukaryotic translation initiation factor 2C, 3 isoform
a [Homo sapiens]
Length = 860
Score = 165 bits (417), Expect = 2e-40
Identities = 184/808 (22%), Positives = 344/808 (42%), Gaps = 95/808 (11%)
Query: 100 GSSGIPVKLVTNLFNLDFPQDWQLYQYHVTYIPDLASRRLR---IALLYSHSELS---NK 153
G+ G P+KL+ N F ++ P+ +Y Y V PD RR+ + + H +++ ++
Sbjct: 24 GTMGKPIKLLANCFQVEIPKI-DVYLYEVDIKPDKCPRRVNREVVDSMVQHFKVTIFGDR 82
Query: 154 AKAFDGA-ILFLSQKLEEKVT------ELSSETQRGETIKMTI----------------- 189
+DG L+ + L T L E + K++I
Sbjct: 83 RPVYDGKRSLYTANPLPVATTGVDLDVTLPGEGGKDRPFKVSIKFVSRVSWHLLHEVLTG 142
Query: 190 -TLKRELPSSSPVC---IQVFNIIFRKILKKLSMYQIGRNFYNPSEPMEIPQHK-LSLWP 244
TL L P+ + +++ R L + +GR+F++ E + P +W
Sbjct: 143 RTLPEPLELDKPISTNPVHAVDVVLRH-LPSMKYTPVGRSFFSAPEGYDHPLGGGREVWF 201
Query: 245 GFAISVSYFERKLLFSADVSYKVL-RNETVLEFMTALCQ--------RTGLSCFTQTCEK 295
GF SV K++ + DVS + + V++FM + R K
Sbjct: 202 GFHQSVRPAMWKMMLNIDVSATAFYKAQPVIQFMCEVLDIHNIDEQPRPLTDSHRVKFTK 261
Query: 296 QLIGLIVLTRY---NNRTYSIDDIDWSVKPTHTF--QKRDG--TEITYVDYYKQQYDITV 348
++ GL V + R Y + ++ TF Q +G E T Y++++Y + +
Sbjct: 262 EIKGLKVEVTHCGTMRRKYRVCNVTRRPASHQTFPLQLENGQTVERTVAQYFREKYTLQL 321
Query: 349 SDLNQPMLVSLLKKKRNDNSEAQLAHLIPELCFLTGLTDQATSDFQLMKAVAEKTRLSPS 408
+ P L + +++++ ++ +++ + LTD TS ++KA A S
Sbjct: 322 KYPHLPCL-QVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTST--MIKATAR----SAP 374
Query: 409 GRQQRLARLVDNIQRNTNARFELETWGLHFGSQIS-----LTGRIVPSEKILMQDHICQP 463
RQ+ ++RLV +A +E + + F ++ +TGR++P+ +
Sbjct: 375 DRQEEISRLV------RSANYETDPFVQEFQFKVRDEMAHVTGRVLPAPMLQYGGRNRTV 428
Query: 464 VSAADWSKDIRTCKILNAQSLNTWLILC----SDRTEYVAESFLNCLRRVAGSMGFNVDY 519
+ + D+R + + W I C E + + F + LR+++ G +
Sbjct: 429 ATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFTDQLRKISKDAGMPIQG 488
Query: 520 PKIIKVQENPAAFVRAIQQYVD---PDVQLVMCILPSNQKTYYDSIKKYLSSDCPVPSQC 576
A V + +++ +QL++ ILP Y + +K+ + + +QC
Sbjct: 489 QPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAE-VKRVGDTLLGMATQC 547
Query: 577 VLARTLNKQGMMMSIATKIAMQMTCKLGGELWAVEIP-------LKSLMVVGIDVCKDAL 629
V + + K + + +++ KLGG + + +P + ++ +G DV
Sbjct: 548 VQVKNVIKTSPQT--LSNLCLKINVKLGG-INNILVPHQRPSVFQQPVIFLGADVTHPPA 604
Query: 630 S--KDVMVVGCVASVNPRITRWFSRCILQRTMTDVADCLKVFMTGALNKWYKYNHDLPAR 687
K + V S++ +R+ + +QR ++ L + L ++YK P R
Sbjct: 605 GDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVRELLIQFYKSTRFKPTR 664
Query: 688 IIVYRAGVGDGQLKTLIEYEVPQLLSSVAESSSNTSSRLSVIVVRKKCMPRFF----TEM 743
II YR GV +GQ + ++ YE+ + + + ++ IVV+K+ R F TE
Sbjct: 665 IIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVVQKRHHTRLFCADRTER 724
Query: 744 NRTVQNPPLGTVVDSEATRNEWYDFYLISQVACRGTVSPTYYNVIYDDNGLKPDHMQRLT 803
N P GT VD++ T +DFYL S +GT P++Y+V++DDN D +Q LT
Sbjct: 725 VGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHVLWDDNCFTADELQLLT 784
Query: 804 FKLCHLYYNWPGIVSVPAPCQYAHKLTF 831
++LCH Y VS+PAP YAH + F
Sbjct: 785 YQLCHTYVRCTRSVSIPAPAYYAHLVAF 812
>gi|29029593 eukaryotic translation initiation factor 2C, 4 [Homo
sapiens]
Length = 861
Score = 154 bits (390), Expect = 3e-37
Identities = 185/810 (22%), Positives = 341/810 (42%), Gaps = 96/810 (11%)
Query: 100 GSSGIPVKLVTNLFNLDFPQDWQLYQYHVTYIPDLASRRLR---IALLYSHSELS---NK 153
G+ G P++L+ N F + P+ +Y Y V P+ RR+ + + H ++ ++
Sbjct: 22 GTVGKPIRLLANHFQVQIPKI-DVYHYDVDIKPEKRPRRVNREVVDTMVRHFKMQIFGDR 80
Query: 154 AKAFDGAI-LFLSQKL---------------EEKVTELSSETQRGETIKMTITLK----- 192
+DG ++ + L E K Q + + + L+
Sbjct: 81 QPGYDGKRNMYTAHPLPIGRDRVDMEVTLPGEGKDQTFKVSVQWVSVVSLQLLLEALAGH 140
Query: 193 -RELPSSSPVCIQVFNIIFRKILKKLSMYQIGRNFYNPSEPMEIPQHK-LSLWPGFAISV 250
E+P S +Q ++I R L + +GR+F++P E P +W GF SV
Sbjct: 141 LNEVPDDS---VQALDVITRH-LPSMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSV 196
Query: 251 SYFERKLLFSADVSYKVL-RNETVLEFMTALCQRTGLSCFTQTCE--------KQLIGLI 301
++ + DVS R + ++EFM + ++ T+ K++ GL
Sbjct: 197 RPAMWNMMLNIDVSATAFYRAQPIIEFMCEVLDIQNINEQTKPLTDSQRVKFTKEIRGLK 256
Query: 302 VLTRY---NNRTYSIDDIDWSVKPTHTF----QKRDGTEITYVDYYKQQYDITVSDLNQP 354
V + R Y + ++ TF + E T Y+KQ+Y + + + P
Sbjct: 257 VEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLENGQAMECTVAQYFKQKYSLQLKYPHLP 316
Query: 355 MLVSLLKKKRNDNSEAQLAHLIPELCFLTGLTDQATSDFQLMKAVAEKTRLSPSGRQQRL 414
L + +++++ ++ +++ + LTD TS ++KA A S RQ+ +
Sbjct: 317 CL-QVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTST--MIKATAR----SAPDRQEEI 369
Query: 415 ARLVDNIQRNTNARFELETWGLHFGSQIS-LTGRIVPSEKILMQDHICQPVSAADWSKDI 473
+RLV + L+ +G+ ++++ LTGR++P+ + + D+
Sbjct: 370 SRLVKSNSMVGGPDPYLKEFGIVVHNEMTELTGRVLPAPMLQYGGRNKTVATPNQGVWDM 429
Query: 474 RTCKILNAQSLNTWLILC----SDRTEYVAESFLNCLRRVAGSMGFNVD-YPKIIKVQEN 528
R + + W + C E + +SF + LR+++ G + P K +
Sbjct: 430 RGKQFYAGIEIKVWAVACFAPQKQCREDLLKSFTDQLRKISKDAGMPIQGQPCFCKYAQG 489
Query: 529 PAA----FVRAIQQYVDPDVQLVMCILPSNQKTYYDSIKKYLSSDCPVPSQCVLARTLNK 584
+ F YV +QL++ ILP Y + +K+ + + +QCV + + K
Sbjct: 490 ADSVEPMFKHLKMTYVG--LQLIVVILPGKTPVYAE-VKRVGDTLLGMATQCVQVKNVVK 546
Query: 585 QGMMMSIATKIAMQMTCKLGGELWAVEIP-------LKSLMVVGIDVCKDALS--KDVMV 635
+ + +++ KLGG + V +P + ++ +G DV K +
Sbjct: 547 TSPQT--LSNLCLKINAKLGG-INNVLVPHQRPSVFQQPVIFLGADVTHPPAGDGKKPSI 603
Query: 636 VGCVASVNPRITRWFSRCILQRTMTDVADCLKV----------FMTGALNKWYKYNHDLP 685
V S++ +R+ + +Q + +++ L + L ++YK P
Sbjct: 604 AAVVGSMDGHPSRYCATVRVQTSRQEISQELLYSQEVIQDLTNMVRELLIQFYKSTRFKP 663
Query: 686 ARIIVYRAGVGDGQLKTLIEYEVPQLLSSVAESSSNTSSRLSVIVVRKKCMPRFF----T 741
RII YR GV +GQ+K + E+ + + + ++ IVV+K+ R F T
Sbjct: 664 TRIIYYRGGVSEGQMKQVAWPELIAIRKACISLEEDYRPGITYIVVQKRHHTRLFCADKT 723
Query: 742 EMNRTVQNPPLGTVVDSEATRNEWYDFYLISQVACRGTVSPTYYNVIYDDNGLKPDHMQR 801
E N P GT VDS T +DFYL S +GT P++Y V++DDN D +Q
Sbjct: 724 ERVGKSGNVPAGTTVDSTITHPSEFDFYLCSHAGIQGTSRPSHYQVLWDDNCFTADELQL 783
Query: 802 LTFKLCHLYYNWPGIVSVPAPCQYAHKLTF 831
LT++LCH Y VS+PAP YA + F
Sbjct: 784 LTYQLCHTYVRCTRSVSIPAPAYYARLVAF 813
>gi|29337286 eukaryotic translation initiation factor 2C, 3 isoform
b [Homo sapiens]
Length = 626
Score = 145 bits (365), Expect = 2e-34
Identities = 125/524 (23%), Positives = 237/524 (45%), Gaps = 42/524 (8%)
Query: 333 EITYVDYYKQQYDITVSDLNQPMLVSLLKKKRNDNSEAQLAHLIPELCFLTGLTDQATSD 392
E T Y++++Y + + + P L + +++++ ++ +++ + LTD TS
Sbjct: 72 ERTVAQYFREKYTLQLKYPHLPCL-QVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTST 130
Query: 393 FQLMKAVAEKTRLSPSGRQQRLARLVDNIQRNTNARFELETWGLHFGSQIS-----LTGR 447
++KA A S RQ+ ++RLV +A +E + + F ++ +TGR
Sbjct: 131 --MIKATAR----SAPDRQEEISRLV------RSANYETDPFVQEFQFKVRDEMAHVTGR 178
Query: 448 IVPSEKILMQDHICQPVSAADWSKDIRTCKILNAQSLNTWLILC----SDRTEYVAESFL 503
++P+ + + + D+R + + W I C E + + F
Sbjct: 179 VLPAPMLQYGGRNRTVATPSHGVWDMRGKQFHTGVEIKMWAIACFATQRQCREEILKGFT 238
Query: 504 NCLRRVAGSMGFNVDYPKIIKVQENPAAFVRAIQQYVD---PDVQLVMCILPSNQKTYYD 560
+ LR+++ G + A V + +++ +QL++ ILP Y +
Sbjct: 239 DQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAE 298
Query: 561 SIKKYLSSDCPVPSQCVLARTLNKQGMMMSIATKIAMQMTCKLGGELWAVEIP------- 613
+K+ + + +QCV + + K + + +++ KLGG + + +P
Sbjct: 299 -VKRVGDTLLGMATQCVQVKNVIKTSPQT--LSNLCLKINVKLGG-INNILVPHQRPSVF 354
Query: 614 LKSLMVVGIDVCKDALS--KDVMVVGCVASVNPRITRWFSRCILQRTMTDVADCLKVFMT 671
+ ++ +G DV K + V S++ +R+ + +QR ++ L +
Sbjct: 355 QQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQRPRQEIIQDLASMVR 414
Query: 672 GALNKWYKYNHDLPARIIVYRAGVGDGQLKTLIEYEVPQLLSSVAESSSNTSSRLSVIVV 731
L ++YK P RII YR GV +GQ + ++ YE+ + + + ++ IVV
Sbjct: 415 ELLIQFYKSTRFKPTRIIFYRDGVSEGQFRQVLYYELLAIREACISLEKDYQPGITYIVV 474
Query: 732 RKKCMPRFF----TEMNRTVQNPPLGTVVDSEATRNEWYDFYLISQVACRGTVSPTYYNV 787
+K+ R F TE N P GT VD++ T +DFYL S +GT P++Y+V
Sbjct: 475 QKRHHTRLFCADRTERVGRSGNIPAGTTVDTDITHPYEFDFYLCSHAGIQGTSRPSHYHV 534
Query: 788 IYDDNGLKPDHMQRLTFKLCHLYYNWPGIVSVPAPCQYAHKLTF 831
++DDN D +Q LT++LCH Y VS+PAP YAH + F
Sbjct: 535 LWDDNCFTADELQLLTYQLCHTYVRCTRSVSIPAPAYYAHLVAF 578
>gi|108773801 glycine dehydrogenase (decarboxylating) [Homo sapiens]
Length = 1020
Score = 35.0 bits (79), Expect = 0.29
Identities = 29/106 (27%), Positives = 46/106 (43%), Gaps = 11/106 (10%)
Query: 183 ETIKMTITLKRELPSSSPVCIQVFNIIFRKILKKLSMYQ--IGRNFYNPSEPMEIPQHKL 240
+T+ I LKR L PVC I K +++ IG +YN S P I ++ L
Sbjct: 93 KTVPANIRLKRPLKMEDPVCENEILATLHAISSKNQIWRSYIGMGYYNCSVPQTILRNLL 152
Query: 241 SLWPGFAISVSYFERKLLFSADVSYKVLRNETVLEFMTALCQRTGL 286
+ + + + +VS R E++L + T +C TGL
Sbjct: 153 E-------NSGWITQYTPYQPEVSQG--RLESLLNYQTMVCDITGL 189
>gi|29294649 dicer1 [Homo sapiens]
Length = 1922
Score = 33.9 bits (76), Expect = 0.66
Identities = 16/60 (26%), Positives = 33/60 (55%), Gaps = 6/60 (10%)
Query: 301 IVLTRYNN----RTYSIDDIDWSVKPTHTFQKRDGTEITYVDYYKQQYDITVSDLNQPML 356
+++ RY N + + D+ + P F + T+ +YYK +Y++ +++LNQP+L
Sbjct: 931 VIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYE--TFAEYYKTKYNLDLTNLNQPLL 988
>gi|29294651 dicer1 [Homo sapiens]
Length = 1922
Score = 33.9 bits (76), Expect = 0.66
Identities = 16/60 (26%), Positives = 33/60 (55%), Gaps = 6/60 (10%)
Query: 301 IVLTRYNN----RTYSIDDIDWSVKPTHTFQKRDGTEITYVDYYKQQYDITVSDLNQPML 356
+++ RY N + + D+ + P F + T+ +YYK +Y++ +++LNQP+L
Sbjct: 931 VIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYE--TFAEYYKTKYNLDLTNLNQPLL 988
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 31.2 bits (69), Expect = 4.3
Identities = 30/130 (23%), Positives = 55/130 (42%), Gaps = 19/130 (14%)
Query: 305 RYNNRTYSIDDIDWSVKPTHTFQKRDGTEITYVDYYKQQYDITVSDLNQPMLVSLLKKKR 364
+ N+ I+D++ +K Q+ EIT + QQY+ + + Q L+ KK+
Sbjct: 1175 KLTNKNNKIEDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQ--LLVKTKKEL 1232
Query: 365 NDNSEAQLAHLIPELCF-----------------LTGLTDQATSDFQLMKAVAEKTRLSP 407
D+ +A+ HLI + L +T + + +K AE+ + +
Sbjct: 1233 ADSKQAETDHLILQASLKGELEASQQQVEVYKIQLAEITSEKHKIHEHLKTSAEQHQRTL 1292
Query: 408 SGRQQRLARL 417
S QQR+ L
Sbjct: 1293 SAYQQRVTAL 1302
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.134 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,115,509
Number of Sequences: 37866
Number of extensions: 1281778
Number of successful extensions: 2724
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 2677
Number of HSP's gapped (non-prelim): 19
length of query: 852
length of database: 18,247,518
effective HSP length: 111
effective length of query: 741
effective length of database: 14,044,392
effective search space: 10406894472
effective search space used: 10406894472
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.