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Search of human proteins with 22129774
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22129774 hypothetical protein LOC54471 [Homo sapiens]
(463 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22129774 hypothetical protein LOC54471 [Homo sapiens] 927 0.0
gi|222080058 Smith-Magenis syndrome chromosome region, candidate... 358 4e-99
gi|22538488 Smith-Magenis syndrome chromosome region, candidate ... 358 4e-99
gi|222080060 Smith-Magenis syndrome chromosome region, candidate... 79 1e-14
gi|22748791 hypothetical protein LOC126868 [Homo sapiens] 42 0.002
gi|7705266 NCK interacting protein with SH3 domain isoform 1 [Ho... 39 0.008
gi|37577148 NCK interacting protein with SH3 domain isoform 2 [H... 39 0.008
gi|5453730 mab-21-like protein 2 [Homo sapiens] 35 0.19
gi|5031897 mab-21-like protein 1 [Homo sapiens] 34 0.32
gi|18390344 ATR interacting protein isoform 2 [Homo sapiens] 30 3.5
gi|18390347 ATR interacting protein isoform 1 [Homo sapiens] 30 3.5
gi|70608109 integrator complex subunit 8 [Homo sapiens] 30 6.0
>gi|22129774 hypothetical protein LOC54471 [Homo sapiens]
Length = 463
Score = 927 bits (2395), Expect = 0.0
Identities = 463/463 (100%), Positives = 463/463 (100%)
Query: 1 MAGAGERKGKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSP 60
MAGAGERKGKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSP
Sbjct: 1 MAGAGERKGKKDDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTSP 60
Query: 61 TRLSHSGKRSWEEPNWMGSPRLLNRDMKTGLSRSLQTLPTDSSTFDTDTFCPPRPKPVAR 120
TRLSHSGKRSWEEPNWMGSPRLLNRDMKTGLSRSLQTLPTDSSTFDTDTFCPPRPKPVAR
Sbjct: 61 TRLSHSGKRSWEEPNWMGSPRLLNRDMKTGLSRSLQTLPTDSSTFDTDTFCPPRPKPVAR 120
Query: 121 KGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMP 180
KGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMP
Sbjct: 121 KGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPDMP 180
Query: 181 LRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENPEY 240
LRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENPEY
Sbjct: 181 LRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENPEY 240
Query: 241 FPRGSSYWDRCVVGGYLSPKTVADTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEV 300
FPRGSSYWDRCVVGGYLSPKTVADTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEV
Sbjct: 241 FPRGSSYWDRCVVGGYLSPKTVADTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTLEV 300
Query: 301 QYERDKHLFIDFLPSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQADSGCR 360
QYERDKHLFIDFLPSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQADSGCR
Sbjct: 301 QYERDKHLFIDFLPSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQADSGCR 360
Query: 361 SLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQALRGLISYLE 420
SLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQALRGLISYLE
Sbjct: 361 SLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQALRGLISYLE 420
Query: 421 AGVLPSALNPKVNLFAELTPEEIDELGYTLYCSLSEPEVLLQT 463
AGVLPSALNPKVNLFAELTPEEIDELGYTLYCSLSEPEVLLQT
Sbjct: 421 AGVLPSALNPKVNLFAELTPEEIDELGYTLYCSLSEPEVLLQT 463
>gi|222080058 Smith-Magenis syndrome chromosome region, candidate 7
isoform 2 [Homo sapiens]
Length = 465
Score = 358 bits (920), Expect = 4e-99
Identities = 213/466 (45%), Positives = 276/466 (59%), Gaps = 17/466 (3%)
Query: 1 MAGAGERKGKK-DDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTS 59
MA +++GK+ D G+G+ +DF+L+NARLVLGVGGAA+LGIATLAVKR DRA TS
Sbjct: 12 MAEFSQKRGKRRSDEGLGSMVDFLLANARLVLGVGGAAVLGIATLAVKRFIDRA----TS 67
Query: 60 PTRLSHSGKRSWEEPNWM-GSPRLLNRDMKTGLSRSLQTLPTDSSTFDTDTFCPPRPKPV 118
P + SW+E + + +P L R LS+ + L SS + P P
Sbjct: 68 PRDEDDTKADSWKELSLLKATPHLQPRPPPAALSQPVLPLAPSSSAPEGPAETDPEVTPQ 127
Query: 119 ARKGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPD 178
+ L ++LQE+LL + R+R IPA + A AKQ A DI EL+++ R+K P+
Sbjct: 128 LSS------PAPLCLTLQERLLAFERDRVTIPAAQVALAKQLAGDIALELQAYFRSKFPE 181
Query: 179 MPLRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENP 238
+P G LYD LQ ADH++L+VPLVLE LWS +PG DT+ P + VRR
Sbjct: 182 LPFGAFVPGGPLYDGLQAGAADHVRLLVPLVLEPGLWSLVPGVDTVARDPRCWAVRRTQL 241
Query: 239 EYFPRGSSYWDRCVVGGYLSPKTVADTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTL 298
E+ PRGSS WDR +VGGYLS + + + K +A S+NWPAIGSLL +IRP+ E L L
Sbjct: 242 EFCPRGSSPWDRFLVGGYLSSRVLLELLRKALAASVNWPAIGSLLGCLIRPSMASEELLL 301
Query: 299 EVQYERDKHLFIDFL---PSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQA 355
EVQ+ER L + L P V D +L+A P NLW L P E ARLRALD
Sbjct: 302 EVQHER-LELTVAVLVAVPGVDADDRLLLAWPLE-GLAGNLWLQDLYPVEAARLRALDDH 359
Query: 356 DSGCRSLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQALRGL 415
D+G R L +L A+C+ ALG L LT V+L L ++ DW+ + L +RFLQAL L
Sbjct: 360 DAGTRRRLLLLLCAVCRGCSALGQLGRGHLTQVVLRLGEDNVDWTEEALGERFLQALELL 419
Query: 416 ISYLEAGVLPSALNPKVNLFAELTPEEIDELGYTLYCSLSEPEVLL 461
I LE LP NP VNLF+ L EEID++GY LY L EPE LL
Sbjct: 420 IGSLEQASLPCHFNPSVNLFSSLREEEIDDIGYALYSGLQEPEGLL 465
>gi|22538488 Smith-Magenis syndrome chromosome region, candidate 7
isoform 1 [Homo sapiens]
Length = 454
Score = 358 bits (920), Expect = 4e-99
Identities = 213/466 (45%), Positives = 276/466 (59%), Gaps = 17/466 (3%)
Query: 1 MAGAGERKGKK-DDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTS 59
MA +++GK+ D G+G+ +DF+L+NARLVLGVGGAA+LGIATLAVKR DRA TS
Sbjct: 1 MAEFSQKRGKRRSDEGLGSMVDFLLANARLVLGVGGAAVLGIATLAVKRFIDRA----TS 56
Query: 60 PTRLSHSGKRSWEEPNWM-GSPRLLNRDMKTGLSRSLQTLPTDSSTFDTDTFCPPRPKPV 118
P + SW+E + + +P L R LS+ + L SS + P P
Sbjct: 57 PRDEDDTKADSWKELSLLKATPHLQPRPPPAALSQPVLPLAPSSSAPEGPAETDPEVTPQ 116
Query: 119 ARKGQVDLKKSRLRMSLQEKLLTYYRNRAAIPAGEQARAKQAAVDICAELRSFLRAKLPD 178
+ L ++LQE+LL + R+R IPA + A AKQ A DI EL+++ R+K P+
Sbjct: 117 LSS------PAPLCLTLQERLLAFERDRVTIPAAQVALAKQLAGDIALELQAYFRSKFPE 170
Query: 179 MPLRDMYLSGSLYDDLQVVTADHIQLIVPLVLEQNLWSCIPGEDTIMNVPGFFLVRRENP 238
+P G LYD LQ ADH++L+VPLVLE LWS +PG DT+ P + VRR
Sbjct: 171 LPFGAFVPGGPLYDGLQAGAADHVRLLVPLVLEPGLWSLVPGVDTVARDPRCWAVRRTQL 230
Query: 239 EYFPRGSSYWDRCVVGGYLSPKTVADTFEKVVAGSINWPAIGSLLDYVIRPAPPPEALTL 298
E+ PRGSS WDR +VGGYLS + + + K +A S+NWPAIGSLL +IRP+ E L L
Sbjct: 231 EFCPRGSSPWDRFLVGGYLSSRVLLELLRKALAASVNWPAIGSLLGCLIRPSMASEELLL 290
Query: 299 EVQYERDKHLFIDFL---PSVTLGDTVLVAKPHRLAQYDNLWRLSLRPAETARLRALDQA 355
EVQ+ER L + L P V D +L+A P NLW L P E ARLRALD
Sbjct: 291 EVQHER-LELTVAVLVAVPGVDADDRLLLAWPLE-GLAGNLWLQDLYPVEAARLRALDDH 348
Query: 356 DSGCRSLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQALRGL 415
D+G R L +L A+C+ ALG L LT V+L L ++ DW+ + L +RFLQAL L
Sbjct: 349 DAGTRRRLLLLLCAVCRGCSALGQLGRGHLTQVVLRLGEDNVDWTEEALGERFLQALELL 408
Query: 416 ISYLEAGVLPSALNPKVNLFAELTPEEIDELGYTLYCSLSEPEVLL 461
I LE LP NP VNLF+ L EEID++GY LY L EPE LL
Sbjct: 409 IGSLEQASLPCHFNPSVNLFSSLREEEIDDIGYALYSGLQEPEGLL 454
>gi|222080060 Smith-Magenis syndrome chromosome region, candidate 7
isoform 3 [Homo sapiens]
Length = 205
Score = 78.6 bits (192), Expect = 1e-14
Identities = 49/105 (46%), Positives = 66/105 (62%), Gaps = 6/105 (5%)
Query: 1 MAGAGERKGKK-DDNGIGTAIDFVLSNARLVLGVGGAAMLGIATLAVKRMYDRAISAPTS 59
MA +++GK+ D G+G+ +DF+L+NARLVLGVGGAA+LGIATLAVKR DRA TS
Sbjct: 1 MAEFSQKRGKRRSDEGLGSMVDFLLANARLVLGVGGAAVLGIATLAVKRFIDRA----TS 56
Query: 60 PTRLSHSGKRSWEEPNWM-GSPRLLNRDMKTGLSRSLQTLPTDSS 103
P + SW+E + + +P L R LS+ + L SS
Sbjct: 57 PRDEDDTKADSWKELSLLKATPHLQPRPPPAALSQPVLPLAPSSS 101
>gi|22748791 hypothetical protein LOC126868 [Homo sapiens]
Length = 362
Score = 41.6 bits (96), Expect = 0.002
Identities = 33/129 (25%), Positives = 56/129 (43%), Gaps = 9/129 (6%)
Query: 337 WRLSLRPAETARLRALDQADSGCRSLCLKILKAICKSTPALGH---LTASQLTNVILHLA 393
W+LS AE L LD+ D GCR C ++++ + + G+ +T+ L V+
Sbjct: 234 WQLSFLRAEQVLLEQLDE-DGGCRRKCFQVMRHLKEDIWCPGNRPVITSHHLQTVLFWTC 292
Query: 394 QEEA---DWSPDMLADRFLQALRGLISYLEAGVLPSALNPKVNLFAELTPEEIDELGYTL 450
++ DW + + FL+ +R L + L NLF P E+D + L
Sbjct: 293 EKYPHFKDWQ--VFSKAFLRLVRKLHKCVSQHFLKHYFVRNSNLFQCANPTELDTVAQKL 350
Query: 451 YCSLSEPEV 459
L P++
Sbjct: 351 ATFLKNPQI 359
>gi|7705266 NCK interacting protein with SH3 domain isoform 1 [Homo
sapiens]
Length = 722
Score = 39.3 bits (90), Expect = 0.008
Identities = 46/158 (29%), Positives = 68/158 (43%), Gaps = 27/158 (17%)
Query: 92 SRSLQTLPTDSSTFDTDTFCPPRPKPVARKG------QVD---LKKSRLRMSLQEKLLTY 142
S SL TL T SS + + C P P PV R+G QV K S +E++ T
Sbjct: 220 STSLDTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATG 279
Query: 143 YRNRA---------AIPAGEQARAKQAAVDICAELRSFLRAKLPDMPLRDMYLSGSLYDD 193
+ + ++ E+ A +AAV + A+L ++ R+ LS L
Sbjct: 280 TTSASDDLEALGTLSLGTTEEKAAAEAAVP------RTIGAELMELVRRNTGLSHELCRV 333
Query: 194 LQVVTADHIQLIVPL---VLEQNLWSCIPGEDTIMNVP 228
+ HIQ VP V+EQ L S + G+D M +P
Sbjct: 334 AIGIIVGHIQASVPASSPVMEQVLLSLVEGKDLSMALP 371
>gi|37577148 NCK interacting protein with SH3 domain isoform 2 [Homo
sapiens]
Length = 715
Score = 39.3 bits (90), Expect = 0.008
Identities = 46/158 (29%), Positives = 68/158 (43%), Gaps = 27/158 (17%)
Query: 92 SRSLQTLPTDSSTFDTDTFCPPRPKPVARKG------QVD---LKKSRLRMSLQEKLLTY 142
S SL TL T SS + + C P P PV R+G QV K S +E++ T
Sbjct: 213 STSLDTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATG 272
Query: 143 YRNRA---------AIPAGEQARAKQAAVDICAELRSFLRAKLPDMPLRDMYLSGSLYDD 193
+ + ++ E+ A +AAV + A+L ++ R+ LS L
Sbjct: 273 TTSASDDLEALGTLSLGTTEEKAAAEAAVP------RTIGAELMELVRRNTGLSHELCRV 326
Query: 194 LQVVTADHIQLIVPL---VLEQNLWSCIPGEDTIMNVP 228
+ HIQ VP V+EQ L S + G+D M +P
Sbjct: 327 AIGIIVGHIQASVPASSPVMEQVLLSLVEGKDLSMALP 364
>gi|5453730 mab-21-like protein 2 [Homo sapiens]
Length = 359
Score = 34.7 bits (78), Expect = 0.19
Identities = 30/104 (28%), Positives = 42/104 (40%), Gaps = 11/104 (10%)
Query: 337 WRLSLRPAETARLRALDQADSGCRSLCLKILKAICKSTPALGH--LTASQLTNVILHLAQ 394
W L AE L GCR+ CL +LK + L L + ++L+ +
Sbjct: 230 WVLQFGEAENRLLMG------GCRNKCLSVLKTLRDRHLELPGQPLNNYHMKTLLLYECE 283
Query: 395 E---EADWSPDMLADRFLQALRGLISYLEAGVLPSALNPKVNLF 435
+ E DW L DR L LIS L+ P P ++LF
Sbjct: 284 KHPRETDWDESCLGDRLNGILLQLISCLQCRRCPHYFLPNLDLF 327
>gi|5031897 mab-21-like protein 1 [Homo sapiens]
Length = 359
Score = 33.9 bits (76), Expect = 0.32
Identities = 25/83 (30%), Positives = 32/83 (38%), Gaps = 5/83 (6%)
Query: 358 GCRSLCLKILKAICKST-----PALGHLTASQLTNVILHLAQEEADWSPDMLADRFLQAL 412
GCR CL ILK + L + L + E+DW L DR L
Sbjct: 245 GCRKKCLSILKTLRDRHLELPGQPLNNYHMKTLVSYECEKHPRESDWDESCLGDRLNGIL 304
Query: 413 RGLISYLEAGVLPSALNPKVNLF 435
LIS L+ P P ++LF
Sbjct: 305 LQLISCLQCRRCPHYFLPNLDLF 327
>gi|18390344 ATR interacting protein isoform 2 [Homo sapiens]
Length = 764
Score = 30.4 bits (67), Expect = 3.5
Identities = 39/123 (31%), Positives = 54/123 (43%), Gaps = 19/123 (15%)
Query: 346 TARLRALDQADSGCRSLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLA 405
T+ LR + D G L +L + S+ A GHL AS LT + L + + S D L
Sbjct: 523 TSALRGVAD-DQGQHPLLKMLLHLLAFSSAATGHLQASVLTQCLKVLVKLAENTSCDFL- 580
Query: 406 DRFLQALRGLISYLEAGVLPSALNPKVNLFAELTPEEI-------DELGYTLYCSLSEPE 458
RF + VLP L+P+ L + L E+ D+L L CS SE
Sbjct: 581 PRFQCVFQ---------VLPKCLSPETPLPSVLLAVELLSLLADHDQLAPQL-CSHSEGC 630
Query: 459 VLL 461
+LL
Sbjct: 631 LLL 633
>gi|18390347 ATR interacting protein isoform 1 [Homo sapiens]
Length = 791
Score = 30.4 bits (67), Expect = 3.5
Identities = 39/123 (31%), Positives = 54/123 (43%), Gaps = 19/123 (15%)
Query: 346 TARLRALDQADSGCRSLCLKILKAICKSTPALGHLTASQLTNVILHLAQEEADWSPDMLA 405
T+ LR + D G L +L + S+ A GHL AS LT + L + + S D L
Sbjct: 523 TSALRGVAD-DQGQHPLLKMLLHLLAFSSAATGHLQASVLTQCLKVLVKLAENTSCDFL- 580
Query: 406 DRFLQALRGLISYLEAGVLPSALNPKVNLFAELTPEEI-------DELGYTLYCSLSEPE 458
RF + VLP L+P+ L + L E+ D+L L CS SE
Sbjct: 581 PRFQCVFQ---------VLPKCLSPETPLPSVLLAVELLSLLADHDQLAPQL-CSHSEGC 630
Query: 459 VLL 461
+LL
Sbjct: 631 LLL 633
>gi|70608109 integrator complex subunit 8 [Homo sapiens]
Length = 995
Score = 29.6 bits (65), Expect = 6.0
Identities = 17/63 (26%), Positives = 31/63 (49%)
Query: 151 AGEQARAKQAAVDICAELRSFLRAKLPDMPLRDMYLSGSLYDDLQVVTADHIQLIVPLVL 210
AG ++ D+ + +R +L +LPD+PLR + + L +++ L VP L
Sbjct: 625 AGTGQAGERPPSDLISRVRGYLEMRLPDIPLRQVIAEECVAFMLNWRENEYLTLQVPAFL 684
Query: 211 EQN 213
Q+
Sbjct: 685 LQS 687
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,489,923
Number of Sequences: 37866
Number of extensions: 853162
Number of successful extensions: 1827
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 1811
Number of HSP's gapped (non-prelim): 14
length of query: 463
length of database: 18,247,518
effective HSP length: 106
effective length of query: 357
effective length of database: 14,233,722
effective search space: 5081438754
effective search space used: 5081438754
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.