Search of human proteins with 221139815

Search of human proteins with 221139815

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|221139815 LEM domain containing 2 isoform 2 [Homo sapiens]
         (201 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31044432 LEM domain containing 2 isoform 1 [Homo sapiens]          410   e-115
gi|221139815 LEM domain containing 2 isoform 2 [Homo sapiens]         410   e-115
gi|7706607 LEM domain containing 3 [Homo sapiens]                     171   3e-43
gi|68077164 Yeast Sps1/Ste20-related kinase 4 isoform 1 [Homo sa...    29   3.1  
gi|63998898 Yeast Sps1/Ste20-related kinase 4 isoform 2 [Homo sa...    29   3.1  
gi|55769554 protein tyrosine phosphatase, receptor type, f polyp...    28   4.0  
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    28   5.2  
gi|56961680 coiled-coil domain containing 147 [Homo sapiens]           28   5.2  
gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens]    28   6.9  
gi|51093834 hypothetical protein LOC126859 isoform 2 [Homo sapiens]    28   6.9  
gi|126116596 asp (abnormal spindle)-like, microcephaly associate...    27   9.0  
gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo sa...    27   9.0  
gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo sap...    27   9.0  

>gi|31044432 LEM domain containing 2 isoform 1 [Homo sapiens]
          Length = 503

 Score =  410 bits (1053), Expect = e-115
 Identities = 201/201 (100%), Positives = 201/201 (100%)

Query: 1   MEAQEYIANVTSSSSAKFEAALTWILSSNKDVGIWLKGEDQSELVTTVDKVVCLESAHPR 60
           MEAQEYIANVTSSSSAKFEAALTWILSSNKDVGIWLKGEDQSELVTTVDKVVCLESAHPR
Sbjct: 303 MEAQEYIANVTSSSSAKFEAALTWILSSNKDVGIWLKGEDQSELVTTVDKVVCLESAHPR 362

Query: 61  MGVGCRLSRALLTAVTNVLIFFWCLAFLWGLLILLKYRWRKLEEEEQAMYEMVKKIIDVV 120
           MGVGCRLSRALLTAVTNVLIFFWCLAFLWGLLILLKYRWRKLEEEEQAMYEMVKKIIDVV
Sbjct: 363 MGVGCRLSRALLTAVTNVLIFFWCLAFLWGLLILLKYRWRKLEEEEQAMYEMVKKIIDVV 422

Query: 121 QDHYVDWEQDMERYPYVGILHVRDSLIPPQSRRRMKRVWDRAVEFLASNESRIQTESHRV 180
           QDHYVDWEQDMERYPYVGILHVRDSLIPPQSRRRMKRVWDRAVEFLASNESRIQTESHRV
Sbjct: 423 QDHYVDWEQDMERYPYVGILHVRDSLIPPQSRRRMKRVWDRAVEFLASNESRIQTESHRV 482

Query: 181 AGEDMLVWRWTKPSSFSDSER 201
           AGEDMLVWRWTKPSSFSDSER
Sbjct: 483 AGEDMLVWRWTKPSSFSDSER 503


>gi|221139815 LEM domain containing 2 isoform 2 [Homo sapiens]
          Length = 201

 Score =  410 bits (1053), Expect = e-115
 Identities = 201/201 (100%), Positives = 201/201 (100%)

Query: 1   MEAQEYIANVTSSSSAKFEAALTWILSSNKDVGIWLKGEDQSELVTTVDKVVCLESAHPR 60
           MEAQEYIANVTSSSSAKFEAALTWILSSNKDVGIWLKGEDQSELVTTVDKVVCLESAHPR
Sbjct: 1   MEAQEYIANVTSSSSAKFEAALTWILSSNKDVGIWLKGEDQSELVTTVDKVVCLESAHPR 60

Query: 61  MGVGCRLSRALLTAVTNVLIFFWCLAFLWGLLILLKYRWRKLEEEEQAMYEMVKKIIDVV 120
           MGVGCRLSRALLTAVTNVLIFFWCLAFLWGLLILLKYRWRKLEEEEQAMYEMVKKIIDVV
Sbjct: 61  MGVGCRLSRALLTAVTNVLIFFWCLAFLWGLLILLKYRWRKLEEEEQAMYEMVKKIIDVV 120

Query: 121 QDHYVDWEQDMERYPYVGILHVRDSLIPPQSRRRMKRVWDRAVEFLASNESRIQTESHRV 180
           QDHYVDWEQDMERYPYVGILHVRDSLIPPQSRRRMKRVWDRAVEFLASNESRIQTESHRV
Sbjct: 121 QDHYVDWEQDMERYPYVGILHVRDSLIPPQSRRRMKRVWDRAVEFLASNESRIQTESHRV 180

Query: 181 AGEDMLVWRWTKPSSFSDSER 201
           AGEDMLVWRWTKPSSFSDSER
Sbjct: 181 AGEDMLVWRWTKPSSFSDSER 201


>gi|7706607 LEM domain containing 3 [Homo sapiens]
          Length = 911

 Score =  171 bits (434), Expect = 3e-43
 Identities = 86/197 (43%), Positives = 121/197 (61%)

Query: 2   EAQEYIANVTSSSSAKFEAALTWILSSNKDVGIWLKGEDQSELVTTVDKVVCLESAHPRM 61
           EA  Y+ ++       F  +L WIL + KDVGI   G    E +T +  V  L+S  P M
Sbjct: 559 EAAAYLKDLGPEYEGIFNTSLQWILENGKDVGIRCVGFGPEEELTNITDVQFLQSTRPLM 618

Query: 62  GVGCRLSRALLTAVTNVLIFFWCLAFLWGLLILLKYRWRKLEEEEQAMYEMVKKIIDVVQ 121
              CR  RA +T    +L+    +  +  +L  +KYRW K EEE + MY+MV KIIDV++
Sbjct: 619 SFWCRFRRAFVTVTHRLLLLCLGVVMVCVVLRYMKYRWTKEEEETRQMYDMVVKIIDVLR 678

Query: 122 DHYVDWEQDMERYPYVGILHVRDSLIPPQSRRRMKRVWDRAVEFLASNESRIQTESHRVA 181
            H    +++ +  PY+ I HVRDSLI P  R++MK+VWDRAV+FLA+NESR++TE+ R+ 
Sbjct: 679 SHNEACQENKDLQPYMPIPHVRDSLIQPHDRKKMKKVWDRAVDFLAANESRVRTETRRIG 738

Query: 182 GEDMLVWRWTKPSSFSD 198
           G D LVWRW +PS+  D
Sbjct: 739 GADFLVWRWIQPSASCD 755


>gi|68077164 Yeast Sps1/Ste20-related kinase 4 isoform 1 [Homo
            sapiens]
          Length = 1328

 Score = 28.9 bits (63), Expect = 3.1
 Identities = 15/36 (41%), Positives = 23/36 (63%), Gaps = 3/36 (8%)

Query: 157  RVWDRAVEFLASNESRIQTESHRVAGEDMLVWRWTK 192
            R++DR  +FL SNE +I +E+   + E +L   WTK
Sbjct: 1031 RIYDREEKFLISNEKKIFSENSLKSEEPIL---WTK 1063


>gi|63998898 Yeast Sps1/Ste20-related kinase 4 isoform 2 [Homo
           sapiens]
          Length = 510

 Score = 28.9 bits (63), Expect = 3.1
 Identities = 15/36 (41%), Positives = 23/36 (63%), Gaps = 3/36 (8%)

Query: 157 RVWDRAVEFLASNESRIQTESHRVAGEDMLVWRWTK 192
           R++DR  +FL SNE +I +E+   + E +L   WTK
Sbjct: 213 RIYDREEKFLISNEKKIFSENSLKSEEPIL---WTK 245


>gi|55769554 protein tyrosine phosphatase, receptor type, f
           polypeptide (PTPRF), interacting protein (liprin), alpha
           4 [Homo sapiens]
          Length = 701

 Score = 28.5 bits (62), Expect = 4.0
 Identities = 15/55 (27%), Positives = 26/55 (47%), Gaps = 2/55 (3%)

Query: 89  WGLLIL--LKYRWRKLEEEEQAMYEMVKKIIDVVQDHYVDWEQDMERYPYVGILH 141
           +G++ L  L Y  ++LE+  +     +K ++    D  V W Q +    Y G LH
Sbjct: 516 YGIMCLKRLNYDRKELEKRREESQHEIKDVLVWTNDQVVHWVQSIGLRDYAGNLH 570


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 28.1 bits (61), Expect = 5.2
 Identities = 21/90 (23%), Positives = 42/90 (46%), Gaps = 2/90 (2%)

Query: 98  RWRKLEEEEQAMYEMVKKIIDVVQDHYVDWEQDMERYPYVGILHVRDSLIPPQSRRRMKR 157
           RW+ L+E E+   E V+K +   +D      +D        +L  +D +   +  RRM+ 
Sbjct: 493 RWKSLDEMEKQQREQVEKNMKDAKDKLESEMEDAYHEHQANLLR-QDLMRRQEELRRMEE 551

Query: 158 VWDRAVEFLASNESRIQTESHRVAGEDMLV 187
           + ++ ++     + R Q E  R   E+M++
Sbjct: 552 LHNQEMQKRKEMQLR-QEEERRRREEEMMI 580


>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
          Length = 872

 Score = 28.1 bits (61), Expect = 5.2
 Identities = 10/20 (50%), Positives = 15/20 (75%)

Query: 97  YRWRKLEEEEQAMYEMVKKI 116
           +RWRKLE  +   YE+++KI
Sbjct: 711 HRWRKLEASDPNAYELIQKI 730


>gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens]
          Length = 1012

 Score = 27.7 bits (60), Expect = 6.9
 Identities = 13/43 (30%), Positives = 24/43 (55%), Gaps = 4/43 (9%)

Query: 91  LLILLKYRWR----KLEEEEQAMYEMVKKIIDVVQDHYVDWEQ 129
           LL  L  +WR    KL++E + M E   + + +V+D  + W++
Sbjct: 451 LLQKLTQKWRNLVNKLKQEVEQMEESTSETLKIVKDGLIKWQE 493


>gi|51093834 hypothetical protein LOC126859 isoform 2 [Homo sapiens]
          Length = 938

 Score = 27.7 bits (60), Expect = 6.9
 Identities = 13/43 (30%), Positives = 24/43 (55%), Gaps = 4/43 (9%)

Query: 91  LLILLKYRWR----KLEEEEQAMYEMVKKIIDVVQDHYVDWEQ 129
           LL  L  +WR    KL++E + M E   + + +V+D  + W++
Sbjct: 451 LLQKLTQKWRNLVNKLKQEVEQMEESTSETLKIVKDGLIKWQE 493


>gi|126116596 asp (abnormal spindle)-like, microcephaly associated
            [Homo sapiens]
          Length = 3477

 Score = 27.3 bits (59), Expect = 9.0
 Identities = 12/45 (26%), Positives = 25/45 (55%), Gaps = 3/45 (6%)

Query: 87   FLWGLLILLKYRWRKL--EEEEQAMYEMVKKIIDVVQDHYVDWEQ 129
            +LW  + + ++ WR     +++Q  YEM+K    ++Q  +  W+Q
Sbjct: 1393 YLWATVTIQRH-WRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQ 1436


>gi|239735580 TRAF2 and NCK interacting kinase isoform 2 [Homo
           sapiens]
          Length = 1352

 Score = 27.3 bits (59), Expect = 9.0
 Identities = 26/97 (26%), Positives = 49/97 (50%), Gaps = 19/97 (19%)

Query: 93  ILLKYRWRKLEEEEQAMYEMVKKIIDVVQDHYVDWE-QDMERYPY--VGILHVRDSLIPP 149
           +LL+Y+ ++LEE+ QA  E +++ +   +D+ V  + Q  E+ P     + H ++ + P 
Sbjct: 471 LLLEYKRKQLEEQRQA--ERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPS 528

Query: 150 QSRRRMKRVWDRAVEFLASNESRIQTES-----HRVA 181
           +     K  W + VE      SR+  +S     H+VA
Sbjct: 529 E-----KPAWAKEVE----ERSRLNRQSSPAMPHKVA 556


>gi|55741807 TRAF2 and NCK interacting kinase isoform 1 [Homo
           sapiens]
          Length = 1360

 Score = 27.3 bits (59), Expect = 9.0
 Identities = 26/97 (26%), Positives = 49/97 (50%), Gaps = 19/97 (19%)

Query: 93  ILLKYRWRKLEEEEQAMYEMVKKIIDVVQDHYVDWE-QDMERYPY--VGILHVRDSLIPP 149
           +LL+Y+ ++LEE+ QA  E +++ +   +D+ V  + Q  E+ P     + H ++ + P 
Sbjct: 471 LLLEYKRKQLEEQRQA--ERLQRQLKQERDYLVSLQHQRQEQRPVEKKPLYHYKEGMSPS 528

Query: 150 QSRRRMKRVWDRAVEFLASNESRIQTES-----HRVA 181
           +     K  W + VE      SR+  +S     H+VA
Sbjct: 529 E-----KPAWAKEVE----ERSRLNRQSSPAMPHKVA 556


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.133    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,135,931
Number of Sequences: 37866
Number of extensions: 261187
Number of successful extensions: 793
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 787
Number of HSP's gapped (non-prelim): 14
length of query: 201
length of database: 18,247,518
effective HSP length: 97
effective length of query: 104
effective length of database: 14,574,516
effective search space: 1515749664
effective search space used: 1515749664
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.