Search of human proteins with 22035624

Search of human proteins with 22035624

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22035624 CDP-diacylglycerol synthase 1 [Homo sapiens]
         (461 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22035624 CDP-diacylglycerol synthase 1 [Homo sapiens]              946   0.0  
gi|20143480 phosphatidate cytidylyltransferase 2 [Homo sapiens]       677   0.0  
gi|29171311 G protein-coupled receptor 109A [Homo sapiens]             36   0.084
gi|157738694 G protein-coupled receptor 109B [Homo sapiens]            35   0.11 
gi|109134327 PTD016 protein [Homo sapiens]                             33   0.71 
gi|45505139 phosphoinositide-3-kinase adaptor protein 1 [Homo sa...    32   1.6  
gi|19923312 v-myc myelocytomatosis viral related oncogene, neuro...    31   2.1  
gi|41281768 cytochrome b-5 isoform 1 [Homo sapiens]                    31   2.7  
gi|222831612 solute carrier family 44, member 2 isoform 1 [Homo ...    30   3.5  
gi|222831610 solute carrier family 44, member 2 isoform 2 [Homo ...    30   3.5  
gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]    30   4.6  
gi|55741677 SET domain containing 1A [Homo sapiens]                    30   6.0  
gi|163965434 dapper, antagonist of beta-catenin, homolog 2 [Homo...    30   6.0  
gi|19913406 DNA topoisomerase II, alpha isozyme [Homo sapiens]         29   7.9  
gi|7706589 GNAS complex locus NESP55 [Homo sapiens]                    29   7.9  

>gi|22035624 CDP-diacylglycerol synthase 1 [Homo sapiens]
          Length = 461

 Score =  946 bits (2445), Expect = 0.0
 Identities = 461/461 (100%), Positives = 461/461 (100%)

Query: 1   MLELRHRGSCPGPREAVSPPHREGEAAGGDHETESTSDKETDIDDRYGDLDSRTDSDIPE 60
           MLELRHRGSCPGPREAVSPPHREGEAAGGDHETESTSDKETDIDDRYGDLDSRTDSDIPE
Sbjct: 1   MLELRHRGSCPGPREAVSPPHREGEAAGGDHETESTSDKETDIDDRYGDLDSRTDSDIPE 60

Query: 61  IPPSSDRTPEILKKALSGLSSRWKNWWIRGILTLTMISLFFLIIYMGSFMLMLLVLGIQV 120
           IPPSSDRTPEILKKALSGLSSRWKNWWIRGILTLTMISLFFLIIYMGSFMLMLLVLGIQV
Sbjct: 61  IPPSSDRTPEILKKALSGLSSRWKNWWIRGILTLTMISLFFLIIYMGSFMLMLLVLGIQV 120

Query: 121 KCFHEIITIGYRVYHSYDLPWFRTLSWYFLLCVNYFFYGETVADYFATFVQREEQLQFLI 180
           KCFHEIITIGYRVYHSYDLPWFRTLSWYFLLCVNYFFYGETVADYFATFVQREEQLQFLI
Sbjct: 121 KCFHEIITIGYRVYHSYDLPWFRTLSWYFLLCVNYFFYGETVADYFATFVQREEQLQFLI 180

Query: 181 RYHRFISFALYLAGFCMFVLSLVKKHYRLQFYMFAWTHVTLLITVTQSHLVIQNLFEGMI 240
           RYHRFISFALYLAGFCMFVLSLVKKHYRLQFYMFAWTHVTLLITVTQSHLVIQNLFEGMI
Sbjct: 181 RYHRFISFALYLAGFCMFVLSLVKKHYRLQFYMFAWTHVTLLITVTQSHLVIQNLFEGMI 240

Query: 241 WFLVPISSVICNDITAYLFGFFFGRTPLIKLSPKKTWEGFIGGFFSTVVFGFIAAYVLSK 300
           WFLVPISSVICNDITAYLFGFFFGRTPLIKLSPKKTWEGFIGGFFSTVVFGFIAAYVLSK
Sbjct: 241 WFLVPISSVICNDITAYLFGFFFGRTPLIKLSPKKTWEGFIGGFFSTVVFGFIAAYVLSK 300

Query: 301 YQYFVCPVEYRSDVNSFVTECEPSELFQLQTYSLPPFLKAVLRQERVSLYPFQIHSIALS 360
           YQYFVCPVEYRSDVNSFVTECEPSELFQLQTYSLPPFLKAVLRQERVSLYPFQIHSIALS
Sbjct: 301 YQYFVCPVEYRSDVNSFVTECEPSELFQLQTYSLPPFLKAVLRQERVSLYPFQIHSIALS 360

Query: 361 TFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVHVYITSFIRG 420
           TFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVHVYITSFIRG
Sbjct: 361 TFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVHVYITSFIRG 420

Query: 421 PNPSKVLQQLLVLQPEQQLNIYKTLKTHLIEKGILQPTLKV 461
           PNPSKVLQQLLVLQPEQQLNIYKTLKTHLIEKGILQPTLKV
Sbjct: 421 PNPSKVLQQLLVLQPEQQLNIYKTLKTHLIEKGILQPTLKV 461


>gi|20143480 phosphatidate cytidylyltransferase 2 [Homo sapiens]
          Length = 445

 Score =  677 bits (1746), Expect = 0.0
 Identities = 326/458 (71%), Positives = 380/458 (82%), Gaps = 17/458 (3%)

Query: 1   MLELRHRGSCPGPREAVSPPHREGEAAGGDHETESTSDKETDIDDRYGDLDSRTDSDIPE 60
           M ELR R +     E V+PP  +      + E+E+  D ET  D      +SR +S    
Sbjct: 1   MTELRQRVA----HEPVAPPEDK------ESESEAKVDGETASDS-----ESRAES--AP 43

Query: 61  IPPSSDRTPEILKKALSGLSSRWKNWWIRGILTLTMISLFFLIIYMGSFMLMLLVLGIQV 120
           +P S+D TPE+L +ALS LSSRWKNWW+RGILTL MI+ FF+IIY+G  +LM++V+ +Q+
Sbjct: 44  LPVSADDTPEVLNRALSNLSSRWKNWWVRGILTLAMIAFFFIIIYLGPMVLMIIVMCVQI 103

Query: 121 KCFHEIITIGYRVYHSYDLPWFRTLSWYFLLCVNYFFYGETVADYFATFVQREEQLQFLI 180
           KCFHEIITIGY VYHSYDLPWFRTLSWYFLLCVNYFFYGETV DYF T VQREE L+ L 
Sbjct: 104 KCFHEIITIGYNVYHSYDLPWFRTLSWYFLLCVNYFFYGETVTDYFFTLVQREEPLRILS 163

Query: 181 RYHRFISFALYLAGFCMFVLSLVKKHYRLQFYMFAWTHVTLLITVTQSHLVIQNLFEGMI 240
           +YHRFISF LYL GFCMFVLSLVKKHYRLQFYMF WTHVTLLI VTQSHLVI NLFEGMI
Sbjct: 164 KYHRFISFTLYLIGFCMFVLSLVKKHYRLQFYMFGWTHVTLLIVVTQSHLVIHNLFEGMI 223

Query: 241 WFLVPISSVICNDITAYLFGFFFGRTPLIKLSPKKTWEGFIGGFFSTVVFGFIAAYVLSK 300
           WF+VPIS VICNDI AY+FGFFFGRTPLIKLSPKKTWEGFIGGFF+TVVFG + +YV+S 
Sbjct: 224 WFIVPISCVICNDIMAYMFGFFFGRTPLIKLSPKKTWEGFIGGFFATVVFGLLLSYVMSG 283

Query: 301 YQYFVCPVEYRSDVNSFVTECEPSELFQLQTYSLPPFLKAVLRQERVSLYPFQIHSIALS 360
           Y+ FVCPVEY +D NSF  +CEPS+LF+LQ Y++P  +++V+  + V +YPFQIHSIALS
Sbjct: 284 YRCFVCPVEYNNDTNSFTVDCEPSDLFRLQEYNIPGVIQSVIGWKTVRMYPFQIHSIALS 343

Query: 361 TFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVHVYITSFIRG 420
           TFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFV+VYI SFIRG
Sbjct: 344 TFASLIGPFGGFFASGFKRAFKIKDFANTIPGHGGIMDRFDCQYLMATFVNVYIASFIRG 403

Query: 421 PNPSKVLQQLLVLQPEQQLNIYKTLKTHLIEKGILQPT 458
           PNPSK++QQ L L+P+QQL+I+ TL++HLI+KG+L  T
Sbjct: 404 PNPSKLIQQFLTLRPDQQLHIFNTLRSHLIDKGMLTST 441


>gi|29171311 G protein-coupled receptor 109A [Homo sapiens]
          Length = 363

 Score = 35.8 bits (81), Expect = 0.084
 Identities = 22/88 (25%), Positives = 45/88 (51%), Gaps = 8/88 (9%)

Query: 89  RGILTLTMISLFFLIIYMGSFMLMLLVLGIQVKCFHEIITIGYRVYHSYDLPWFRTLSWY 148
           R I  + ++++ F+I ++ S ++ + +  +     H   T    VY S DL +F TLS+ 
Sbjct: 228 RAITFIMVVAIVFVICFLPSVVVRIRIFWL----LHTSGTQNCEVYRSVDLAFFITLSFT 283

Query: 149 FLLC----VNYFFYGETVADYFATFVQR 172
           ++      V Y+F   +  ++F+T + R
Sbjct: 284 YMNSMLDPVVYYFSSPSFPNFFSTLINR 311


>gi|157738694 G protein-coupled receptor 109B [Homo sapiens]
          Length = 387

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 22/88 (25%), Positives = 45/88 (51%), Gaps = 8/88 (9%)

Query: 89  RGILTLTMISLFFLIIYMGSFMLMLLVLGIQVKCFHEIITIGYRVYHSYDLPWFRTLSWY 148
           R I  + ++++ F+I ++ S ++ + +  +     H   T    VY S DL +F TLS+ 
Sbjct: 228 RAITFIMVVAIVFVICFLPSVVVRIHIFWL----LHTSGTQNCEVYRSVDLAFFITLSFT 283

Query: 149 FLLC----VNYFFYGETVADYFATFVQR 172
           ++      V Y+F   +  ++F+T + R
Sbjct: 284 YMNSMLDPVVYYFSSPSFPNFFSTLINR 311


>gi|109134327 PTD016 protein [Homo sapiens]
          Length = 435

 Score = 32.7 bits (73), Expect = 0.71
 Identities = 34/125 (27%), Positives = 51/125 (40%), Gaps = 32/125 (25%)

Query: 81  SRWKNWWIRGILTLTMISLFFLIIYMGSFMLMLLVLGIQVKCFHEIITIGYRVYHSYDLP 140
           S W+ +WI GI T  ++  FF    MG   L+LLV                    S+ +P
Sbjct: 243 SFWEVFWIVGI-TDFILKFFF----MGLKCLILLV-------------------PSFIMP 278

Query: 141 WFRTLSWYFLLCVNYFFYGETVADYFATFVQREEQLQFLIRYHRFISFALYLAGFCMFVL 200
           +     WY LL        E +  Y+ TFV      ++LI Y  F +   +  G  + +L
Sbjct: 279 FKSKGYWYMLL--------EELCQYYRTFVPIPVWFRYLISYGEFGNVTRWSLGILLALL 330

Query: 201 SLVKK 205
            L+ K
Sbjct: 331 YLILK 335


>gi|45505139 phosphoinositide-3-kinase adaptor protein 1 [Homo
           sapiens]
          Length = 805

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 19/75 (25%)

Query: 12  GPREAVSPPHREGEAAGGDHETESTSDKETDIDDR----------YGDLDSRTDSDIPEI 61
           GPR++V PP    E   GD +T+STS   +   +R           G      D+++PE+
Sbjct: 697 GPRKSVIPPRT--ELRRGDWKTDSTSSTASSTSNRSSTRSLLSVSSGMEGDNEDNEVPEV 754

Query: 62  -------PPSSDRTP 69
                  PP  D TP
Sbjct: 755 TRSRSPGPPQVDGTP 769


>gi|19923312 v-myc myelocytomatosis viral related oncogene,
           neuroblastoma derived [Homo sapiens]
          Length = 464

 Score = 31.2 bits (69), Expect = 2.1
 Identities = 22/69 (31%), Positives = 31/69 (44%), Gaps = 6/69 (8%)

Query: 9   SCPGPREAVSPPHREG-EAAGGDHETESTSDKET-----DIDDRYGDLDSRTDSDIPEIP 62
           + P     V+PP   G + +GGDH+  STS ++T     D DD   D +   D    E  
Sbjct: 226 AAPAGAPGVAPPRPGGRQTSGGDHKALSTSGEDTLSDSDDEDDEEEDEEEEIDVVTVEKR 285

Query: 63  PSSDRTPEI 71
            SS  T  +
Sbjct: 286 RSSSNTKAV 294


>gi|41281768 cytochrome b-5 isoform 1 [Homo sapiens]
          Length = 134

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 23/78 (29%), Positives = 32/78 (41%), Gaps = 1/78 (1%)

Query: 25  EAAGGDHETESTSDKETDIDDRYGDLDSRTDSDIPEIPPSSDRTPEILKKALSGLSSRWK 84
           E AGGD  TE+  D     D R            P+  P  ++ PE L   +   SS W 
Sbjct: 53  EQAGGD-ATENFEDVGHSTDAREMSKTFIIGELHPDDRPKLNKPPETLITTIDSSSSWWT 111

Query: 85  NWWIRGILTLTMISLFFL 102
           NW I  I  + +  ++ L
Sbjct: 112 NWVIPAISAVAVALMYRL 129


>gi|222831612 solute carrier family 44, member 2 isoform 1 [Homo
           sapiens]
          Length = 706

 Score = 30.4 bits (67), Expect = 3.5
 Identities = 32/137 (23%), Positives = 57/137 (41%), Gaps = 9/137 (6%)

Query: 3   ELRHRGSCPGPREAVSPPHREGEAAGGDHETESTSDKETDIDDRYGDLDSRTDSDIPEIP 62
           E+   G CP       P  R    A   ++       ET  +D +G   + TD  + E  
Sbjct: 151 EVLQDGDCPAVLIPSKPLARRCFPAIHAYKGVLMVGNETTYEDGHGSRKNITD--LVEGA 208

Query: 63  PSSDRTPEILKKALSGLSSRWKNWW--IRGILTLTMISLFFLIIYMGSFMLMLLVLGIQV 120
             ++   E  + A+        +W+  I G++    +SL F+I+      +M+ V+ I V
Sbjct: 209 KKANGVLEARQLAMRIFEDYTVSWYWIIIGLVIAMAMSLLFIILLRFLAGIMVWVMIIMV 268

Query: 121 KCFHEIITIGYRVYHSY 137
                I+ +GY ++H Y
Sbjct: 269 -----ILVLGYGIFHCY 280


>gi|222831610 solute carrier family 44, member 2 isoform 2 [Homo
           sapiens]
          Length = 704

 Score = 30.4 bits (67), Expect = 3.5
 Identities = 32/137 (23%), Positives = 57/137 (41%), Gaps = 9/137 (6%)

Query: 3   ELRHRGSCPGPREAVSPPHREGEAAGGDHETESTSDKETDIDDRYGDLDSRTDSDIPEIP 62
           E+   G CP       P  R    A   ++       ET  +D +G   + TD  + E  
Sbjct: 149 EVLQDGDCPAVLIPSKPLARRCFPAIHAYKGVLMVGNETTYEDGHGSRKNITD--LVEGA 206

Query: 63  PSSDRTPEILKKALSGLSSRWKNWW--IRGILTLTMISLFFLIIYMGSFMLMLLVLGIQV 120
             ++   E  + A+        +W+  I G++    +SL F+I+      +M+ V+ I V
Sbjct: 207 KKANGVLEARQLAMRIFEDYTVSWYWIIIGLVIAMAMSLLFIILLRFLAGIMVWVMIIMV 266

Query: 121 KCFHEIITIGYRVYHSY 137
                I+ +GY ++H Y
Sbjct: 267 -----ILVLGYGIFHCY 278


>gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]
          Length = 1759

 Score = 30.0 bits (66), Expect = 4.6
 Identities = 24/83 (28%), Positives = 31/83 (37%), Gaps = 19/83 (22%)

Query: 11   PGPREAVSPPHREGEAAGG------------------DHETESTSDKETDIDDRYGDLDS 52
            PGP +A +P  REG AA                    + E E   D++ D DD   D D 
Sbjct: 1649 PGPPDAAAPGPREGAAAAAAAAGESSQEDEEEELELPEEEAEDDEDEDDDEDDDDED-DD 1707

Query: 53   RTDSDIPEIPPSSDRTPEILKKA 75
              D D      S +  PE   +A
Sbjct: 1708 EDDDDEDLRTDSEESLPEAAAEA 1730


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 29.6 bits (65), Expect = 6.0
 Identities = 20/67 (29%), Positives = 30/67 (44%)

Query: 15   EAVSPPHREGEAAGGDHETESTSDKETDIDDRYGDLDSRTDSDIPEIPPSSDRTPEILKK 74
            EAV    +E E + G+ E   +S K +   D  G+ DS +DS+      SS  +      
Sbjct: 992  EAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSS 1051

Query: 75   ALSGLSS 81
            + S  SS
Sbjct: 1052 SSSSSSS 1058


>gi|163965434 dapper, antagonist of beta-catenin, homolog 2 [Homo
           sapiens]
          Length = 774

 Score = 29.6 bits (65), Expect = 6.0
 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 3/54 (5%)

Query: 5   RHRGSCPGPREAVSPPHREGEAAGGDHETESTSDKETDIDDRYGDLDSRTDSDI 58
           +H   C     +V P   EGE++  DH T    D+E+   D  G   SR D D+
Sbjct: 665 KHSAECDPRFPSVIPETSEGESS--DHTTNRFGDRESSSSDEEGGAQSR-DCDL 715


>gi|19913406 DNA topoisomerase II, alpha isozyme [Homo sapiens]
          Length = 1531

 Score = 29.3 bits (64), Expect = 7.9
 Identities = 19/61 (31%), Positives = 31/61 (50%), Gaps = 6/61 (9%)

Query: 20   PHREGEAAGGDHETESTSDKETDIDDRYGDLDSRTDSD--IPE--IPPSSDRTPEILKKA 75
            P RE E      +T+ T D ++D D  + D D +TD +  +P    PP +  +P++  K 
Sbjct: 1311 PPRETEPRRAATKTKFTMDLDSDED--FSDFDEKTDDEDFVPSDASPPKTKTSPKLSNKE 1368

Query: 76   L 76
            L
Sbjct: 1369 L 1369


>gi|7706589 GNAS complex locus NESP55 [Homo sapiens]
          Length = 245

 Score = 29.3 bits (64), Expect = 7.9
 Identities = 15/51 (29%), Positives = 24/51 (47%)

Query: 30  DHETESTSDKETDIDDRYGDLDSRTDSDIPEIPPSSDRTPEILKKALSGLS 80
           D+ETES ++ E + +  +        +  PE  P  DR P + K +  G S
Sbjct: 108 DYETESETESEIESETDFETEPETAPTTEPETEPEDDRGPVVPKHSTFGQS 158


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.328    0.143    0.453 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,511,732
Number of Sequences: 37866
Number of extensions: 757173
Number of successful extensions: 3048
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 3041
Number of HSP's gapped (non-prelim): 17
length of query: 461
length of database: 18,247,518
effective HSP length: 106
effective length of query: 355
effective length of database: 14,233,722
effective search space: 5052971310
effective search space used: 5052971310
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.