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Search of human proteins with 114431236
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|114431236 zinc finger protein 462 [Homo sapiens]
(2506 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|114431236 zinc finger protein 462 [Homo sapiens] 5212 0.0
gi|118600985 zinc finger protein 91 [Homo sapiens] 130 2e-29
gi|157676340 zinc finger protein 142 [Homo sapiens] 129 5e-29
gi|239757212 PREDICTED: similar to hCG1773661 [Homo sapiens] 122 6e-27
gi|239751718 PREDICTED: similar to hCG1773661 [Homo sapiens] 122 6e-27
gi|239746221 PREDICTED: hypothetical protein XP_002343677 [Homo ... 122 6e-27
gi|210031219 zinc finger protein 845 [Homo sapiens] 113 2e-24
gi|157167158 zinc finger protein 808 [Homo sapiens] 113 2e-24
gi|162417982 zinc finger protein 64 isoform d [Homo sapiens] 113 3e-24
gi|6005976 zinc finger protein 208 [Homo sapiens] 111 8e-24
gi|239757222 PREDICTED: zinc finger protein 726 [Homo sapiens] 109 3e-23
gi|239751727 PREDICTED: zinc finger protein 726 [Homo sapiens] 109 3e-23
gi|239746228 PREDICTED: zinc finger protein 726 [Homo sapiens] 109 3e-23
gi|55769537 zinc finger protein 658 [Homo sapiens] 108 5e-23
gi|222831664 zinc finger protein 184 [Homo sapiens] 108 7e-23
gi|57165428 zinc finger protein 28 [Homo sapiens] 103 3e-21
gi|190194429 zinc finger protein 267 [Homo sapiens] 102 6e-21
gi|22095393 zinc finger protein 420 [Homo sapiens] 101 8e-21
gi|11386193 zinc finger protein 197 isoform 1 [Homo sapiens] 101 1e-20
gi|38570117 zinc finger protein 569 [Homo sapiens] 101 1e-20
gi|68303809 zinc finger protein 43 [Homo sapiens] 100 1e-20
gi|209954795 zinc finger protein 761 [Homo sapiens] 100 2e-20
gi|221307571 zinc finger protein 234 [Homo sapiens] 100 3e-20
gi|24307913 zinc finger protein 234 [Homo sapiens] 100 3e-20
gi|96303826 zinc finger protein 16 [Homo sapiens] 99 5e-20
gi|38045954 zinc finger protein 16 [Homo sapiens] 99 5e-20
gi|115511042 zinc finger protein 493 isoform 1 [Homo sapiens] 99 7e-20
gi|115511044 zinc finger protein 493 isoform 3 [Homo sapiens] 99 7e-20
gi|71061446 zinc finger protein, X-linked [Homo sapiens] 99 7e-20
gi|40255145 zinc finger protein 555 [Homo sapiens] 98 1e-19
>gi|114431236 zinc finger protein 462 [Homo sapiens]
Length = 2506
Score = 5212 bits (13521), Expect = 0.0
Identities = 2506/2506 (100%), Positives = 2506/2506 (100%)
Query: 1 MEVLQCDGCDFRAPSYEDLKAHIQDVHTAFLQPTDVAEDNVNELRCGSVNASNQTEVEFS 60
MEVLQCDGCDFRAPSYEDLKAHIQDVHTAFLQPTDVAEDNVNELRCGSVNASNQTEVEFS
Sbjct: 1 MEVLQCDGCDFRAPSYEDLKAHIQDVHTAFLQPTDVAEDNVNELRCGSVNASNQTEVEFS 60
Query: 61 SIKDEFAIAEDLSGQNATSLGTGGYYGHSPGYYGQHIAANPKPTNKFFQCKFCVRYFRSK 120
SIKDEFAIAEDLSGQNATSLGTGGYYGHSPGYYGQHIAANPKPTNKFFQCKFCVRYFRSK
Sbjct: 61 SIKDEFAIAEDLSGQNATSLGTGGYYGHSPGYYGQHIAANPKPTNKFFQCKFCVRYFRSK 120
Query: 121 NLLIEHTRKVHGAQAEGSSSGPPVPGSLNYNIMMHEGFGKVFSCQFCTYKSPRRARIIKH 180
NLLIEHTRKVHGAQAEGSSSGPPVPGSLNYNIMMHEGFGKVFSCQFCTYKSPRRARIIKH
Sbjct: 121 NLLIEHTRKVHGAQAEGSSSGPPVPGSLNYNIMMHEGFGKVFSCQFCTYKSPRRARIIKH 180
Query: 181 QKMYHKNNLKETTAPPPAPAPMPDPVVPPVSLQDPCKELPAEVVERSILESMVKPLTKSR 240
QKMYHKNNLKETTAPPPAPAPMPDPVVPPVSLQDPCKELPAEVVERSILESMVKPLTKSR
Sbjct: 181 QKMYHKNNLKETTAPPPAPAPMPDPVVPPVSLQDPCKELPAEVVERSILESMVKPLTKSR 240
Query: 241 GNFCCEWCSYQTPRRERWCDHMMKKHRSMVKILSSLRQQQEGTNLPDVPNKSAPSPTSNS 300
GNFCCEWCSYQTPRRERWCDHMMKKHRSMVKILSSLRQQQEGTNLPDVPNKSAPSPTSNS
Sbjct: 241 GNFCCEWCSYQTPRRERWCDHMMKKHRSMVKILSSLRQQQEGTNLPDVPNKSAPSPTSNS 300
Query: 301 TYLTMNAASREIPNTTVSNFRGSMGNSIMRPNSSASKFSPMSYPQMKPKSPHNSGLVNLT 360
TYLTMNAASREIPNTTVSNFRGSMGNSIMRPNSSASKFSPMSYPQMKPKSPHNSGLVNLT
Sbjct: 301 TYLTMNAASREIPNTTVSNFRGSMGNSIMRPNSSASKFSPMSYPQMKPKSPHNSGLVNLT 360
Query: 361 ERSRYGMTDMTNSSADLETNSMLNDSSSDEELNEIDSENGLSAMDHQTSGLSAEQLMGSD 420
ERSRYGMTDMTNSSADLETNSMLNDSSSDEELNEIDSENGLSAMDHQTSGLSAEQLMGSD
Sbjct: 361 ERSRYGMTDMTNSSADLETNSMLNDSSSDEELNEIDSENGLSAMDHQTSGLSAEQLMGSD 420
Query: 421 GNKLLETKGIPFRRFMNRFQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCK 480
GNKLLETKGIPFRRFMNRFQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCK
Sbjct: 421 GNKLLETKGIPFRRFMNRFQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCK 480
Query: 481 SSLKLGAHKQCHTGTTSDWDAVNSQSESISSSLNEGVVSYESSSINGRKSGVMLDPLQQQ 540
SSLKLGAHKQCHTGTTSDWDAVNSQSESISSSLNEGVVSYESSSINGRKSGVMLDPLQQQ
Sbjct: 481 SSLKLGAHKQCHTGTTSDWDAVNSQSESISSSLNEGVVSYESSSINGRKSGVMLDPLQQQ 540
Query: 541 QPPQPPPPPPPPPPSQPQPLQQPQPPQLQPPHQVPPQPQTQPPPTQQPQPPTQAAPLHPY 600
QPPQPPPPPPPPPPSQPQPLQQPQPPQLQPPHQVPPQPQTQPPPTQQPQPPTQAAPLHPY
Sbjct: 541 QPPQPPPPPPPPPPSQPQPLQQPQPPQLQPPHQVPPQPQTQPPPTQQPQPPTQAAPLHPY 600
Query: 601 KCTMCNYSTTTLKGLRVHQQHKHSFCDNLPKFEGQPSSLPLENETDSHPSSSNTVKKSQT 660
KCTMCNYSTTTLKGLRVHQQHKHSFCDNLPKFEGQPSSLPLENETDSHPSSSNTVKKSQT
Sbjct: 601 KCTMCNYSTTTLKGLRVHQQHKHSFCDNLPKFEGQPSSLPLENETDSHPSSSNTVKKSQT 660
Query: 661 SILGLSSKNNFVAKASRKLANDFPLDLSPVKKRTRIDEIASNLQSKINQTKQQEDAVINV 720
SILGLSSKNNFVAKASRKLANDFPLDLSPVKKRTRIDEIASNLQSKINQTKQQEDAVINV
Sbjct: 661 SILGLSSKNNFVAKASRKLANDFPLDLSPVKKRTRIDEIASNLQSKINQTKQQEDAVINV 720
Query: 721 EDDEEEEEDNEVEIEVELDREEEPTEPIIEVPTSFSAQQIWVRDTSEPQKEPNFRNITHD 780
EDDEEEEEDNEVEIEVELDREEEPTEPIIEVPTSFSAQQIWVRDTSEPQKEPNFRNITHD
Sbjct: 721 EDDEEEEEDNEVEIEVELDREEEPTEPIIEVPTSFSAQQIWVRDTSEPQKEPNFRNITHD 780
Query: 781 YNATNGAEIELTLSEDEEDYYGSSTNLKDHQVSNTALLNTQTPIYGTEHNSENTDFGDSG 840
YNATNGAEIELTLSEDEEDYYGSSTNLKDHQVSNTALLNTQTPIYGTEHNSENTDFGDSG
Sbjct: 781 YNATNGAEIELTLSEDEEDYYGSSTNLKDHQVSNTALLNTQTPIYGTEHNSENTDFGDSG 840
Query: 841 RLYYCKHCDFNNKSARSVSTHYQRMHPYIKFSFRYILDPNDHSAVYRCLECYIDYTNFED 900
RLYYCKHCDFNNKSARSVSTHYQRMHPYIKFSFRYILDPNDHSAVYRCLECYIDYTNFED
Sbjct: 841 RLYYCKHCDFNNKSARSVSTHYQRMHPYIKFSFRYILDPNDHSAVYRCLECYIDYTNFED 900
Query: 901 LQQHYGEHHPEAMNVLNFDHSDLIYRCRFCSYTSPNVRSLMPHYQRMHPTVKINNAMIFS 960
LQQHYGEHHPEAMNVLNFDHSDLIYRCRFCSYTSPNVRSLMPHYQRMHPTVKINNAMIFS
Sbjct: 901 LQQHYGEHHPEAMNVLNFDHSDLIYRCRFCSYTSPNVRSLMPHYQRMHPTVKINNAMIFS 960
Query: 961 SYVVEQQEGLNTESQTLREILNSAPKNMATSTPVARGGGLPATFNKNTPKTFTPECENQK 1020
SYVVEQQEGLNTESQTLREILNSAPKNMATSTPVARGGGLPATFNKNTPKTFTPECENQK
Sbjct: 961 SYVVEQQEGLNTESQTLREILNSAPKNMATSTPVARGGGLPATFNKNTPKTFTPECENQK 1020
Query: 1021 DPLVNTVVVYDCDVCSFASPNMHSVLVHYQKKHPEEKASYFRIQKTMRMVSVDRGSALSQ 1080
DPLVNTVVVYDCDVCSFASPNMHSVLVHYQKKHPEEKASYFRIQKTMRMVSVDRGSALSQ
Sbjct: 1021 DPLVNTVVVYDCDVCSFASPNMHSVLVHYQKKHPEEKASYFRIQKTMRMVSVDRGSALSQ 1080
Query: 1081 LSFEVGAPMSPKMSNMGSPPPPQPPPPDLSTELYYCKHCSYSNRSVVGVLVHYQKRHPEI 1140
LSFEVGAPMSPKMSNMGSPPPPQPPPPDLSTELYYCKHCSYSNRSVVGVLVHYQKRHPEI
Sbjct: 1081 LSFEVGAPMSPKMSNMGSPPPPQPPPPDLSTELYYCKHCSYSNRSVVGVLVHYQKRHPEI 1140
Query: 1141 KVTAKYIRQAPPTAAMMRGVEGPQGSPRPPAPIQQLNRSSSERDGPPVENEMFFCQHCDY 1200
KVTAKYIRQAPPTAAMMRGVEGPQGSPRPPAPIQQLNRSSSERDGPPVENEMFFCQHCDY
Sbjct: 1141 KVTAKYIRQAPPTAAMMRGVEGPQGSPRPPAPIQQLNRSSSERDGPPVENEMFFCQHCDY 1200
Query: 1201 GNRTVKGVLIHYQKKHRDFKANADVIRQHTATIRSLCDRNQKKPASCVLVSPSNLERDKT 1260
GNRTVKGVLIHYQKKHRDFKANADVIRQHTATIRSLCDRNQKKPASCVLVSPSNLERDKT
Sbjct: 1201 GNRTVKGVLIHYQKKHRDFKANADVIRQHTATIRSLCDRNQKKPASCVLVSPSNLERDKT 1260
Query: 1261 KLRALKCRQCSYTSPYFYALRKHIKKDHPALKATVTSIMRWAFLDGLIEAGYHCEWCIYS 1320
KLRALKCRQCSYTSPYFYALRKHIKKDHPALKATVTSIMRWAFLDGLIEAGYHCEWCIYS
Sbjct: 1261 KLRALKCRQCSYTSPYFYALRKHIKKDHPALKATVTSIMRWAFLDGLIEAGYHCEWCIYS 1320
Query: 1321 HTEPNGLLLHYQRRHPEHYVDYTYMATKLWAGPDPSPPSLTMPAEAKTYRCRDCVFEAVS 1380
HTEPNGLLLHYQRRHPEHYVDYTYMATKLWAGPDPSPPSLTMPAEAKTYRCRDCVFEAVS
Sbjct: 1321 HTEPNGLLLHYQRRHPEHYVDYTYMATKLWAGPDPSPPSLTMPAEAKTYRCRDCVFEAVS 1380
Query: 1381 IWDITNHYQAFHPWAMNGDESVLLDIIKEKDAVEKPILSSEELAGPVNCENSIPTPFPEQ 1440
IWDITNHYQAFHPWAMNGDESVLLDIIKEKDAVEKPILSSEELAGPVNCENSIPTPFPEQ
Sbjct: 1381 IWDITNHYQAFHPWAMNGDESVLLDIIKEKDAVEKPILSSEELAGPVNCENSIPTPFPEQ 1440
Query: 1441 EAECPEDARLSPEKSLQLASANPAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPGMKVKA 1500
EAECPEDARLSPEKSLQLASANPAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPGMKVKA
Sbjct: 1441 EAECPEDARLSPEKSLQLASANPAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPGMKVKA 1500
Query: 1501 ADFAQDIDINPGAVYKCRHCPYINTRIHGVLTHYQKRHPSIKVTAEDFVHDVEQSADISQ 1560
ADFAQDIDINPGAVYKCRHCPYINTRIHGVLTHYQKRHPSIKVTAEDFVHDVEQSADISQ
Sbjct: 1501 ADFAQDIDINPGAVYKCRHCPYINTRIHGVLTHYQKRHPSIKVTAEDFVHDVEQSADISQ 1560
Query: 1561 NDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFDVFSQSPPKLPVPLE 1620
NDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFDVFSQSPPKLPVPLE
Sbjct: 1561 NDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFDVFSQSPPKLPVPLE 1620
Query: 1621 PEMTTEVSPSQVSITEEEVGEEPVSTSHFSTSHLVSHTVFRCQLCKYFCSTRKGIARHYR 1680
PEMTTEVSPSQVSITEEEVGEEPVSTSHFSTSHLVSHTVFRCQLCKYFCSTRKGIARHYR
Sbjct: 1621 PEMTTEVSPSQVSITEEEVGEEPVSTSHFSTSHLVSHTVFRCQLCKYFCSTRKGIARHYR 1680
Query: 1681 IKHNNVRAQPEGKNNLFKCALCAYTNPIRKGLAAHYQKRHDIDAYYTHCLAASRTISDKP 1740
IKHNNVRAQPEGKNNLFKCALCAYTNPIRKGLAAHYQKRHDIDAYYTHCLAASRTISDKP
Sbjct: 1681 IKHNNVRAQPEGKNNLFKCALCAYTNPIRKGLAAHYQKRHDIDAYYTHCLAASRTISDKP 1740
Query: 1741 NKVIIPSPPKDDSPQLSEELRRAVEKKKCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHA 1800
NKVIIPSPPKDDSPQLSEELRRAVEKKKCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHA
Sbjct: 1741 NKVIIPSPPKDDSPQLSEELRRAVEKKKCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHA 1800
Query: 1801 SKLGGYFTAVYADEHEKPTLMEEEERGNFEKAEVEGEAQEIEWLPFRCIKCFKLSFSTAE 1860
SKLGGYFTAVYADEHEKPTLMEEEERGNFEKAEVEGEAQEIEWLPFRCIKCFKLSFSTAE
Sbjct: 1801 SKLGGYFTAVYADEHEKPTLMEEEERGNFEKAEVEGEAQEIEWLPFRCIKCFKLSFSTAE 1860
Query: 1861 LLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHNEEFQK 1920
LLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHNEEFQK
Sbjct: 1861 LLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHNEEFQK 1920
Query: 1921 RAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVPKIKERKVVGYKCKFCVEVHPTL 1980
RAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVPKIKERKVVGYKCKFCVEVHPTL
Sbjct: 1921 RAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVPKIKERKVVGYKCKFCVEVHPTL 1980
Query: 1981 RAICNHLRKHVQYGNVPAVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNL 2040
RAICNHLRKHVQYGNVPAVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNL
Sbjct: 1981 RAICNHLRKHVQYGNVPAVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNL 2040
Query: 2041 DRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKE 2100
DRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKE
Sbjct: 2041 DRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKE 2100
Query: 2101 HSLKVHGKALTLPRPRIVSLLSSHSHHSSQKATPAEEVEDSNDSSYSEPPDVQQQLNHYQ 2160
HSLKVHGKALTLPRPRIVSLLSSHSHHSSQKATPAEEVEDSNDSSYSEPPDVQQQLNHYQ
Sbjct: 2101 HSLKVHGKALTLPRPRIVSLLSSHSHHSSQKATPAEEVEDSNDSSYSEPPDVQQQLNHYQ 2160
Query: 2161 SAALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLF 2220
SAALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLF
Sbjct: 2161 SAALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLF 2220
Query: 2221 KCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREER 2280
KCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREER
Sbjct: 2221 KCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREER 2280
Query: 2281 VVPIEVCRSKLSKYLQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHT 2340
VVPIEVCRSKLSKYLQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHT
Sbjct: 2281 VVPIEVCRSKLSKYLQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHT 2340
Query: 2341 EELDSHLRDEHKVSRNFELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDRELMR 2400
EELDSHLRDEHKVSRNFELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDRELMR
Sbjct: 2341 EELDSHLRDEHKVSRNFELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDRELMR 2400
Query: 2401 FSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRHGMALNDTKQVSREEIHPKEIMENS 2460
FSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRHGMALNDTKQVSREEIHPKEIMENS
Sbjct: 2401 FSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRHGMALNDTKQVSREEIHPKEIMENS 2460
Query: 2461 VKMPSIEEKEDDEAIGIDFSLKNETVAICVVTADKSLLENAEAKKE 2506
VKMPSIEEKEDDEAIGIDFSLKNETVAICVVTADKSLLENAEAKKE
Sbjct: 2461 VKMPSIEEKEDDEAIGIDFSLKNETVAICVVTADKSLLENAEAKKE 2506
>gi|118600985 zinc finger protein 91 [Homo sapiens]
Length = 1191
Score = 130 bits (326), Expect = 2e-29
Identities = 200/844 (23%), Positives = 313/844 (37%), Gaps = 137/844 (16%)
Query: 1650 STSHLVSHT---VFRCQLC-KYFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCALCAYT 1705
S H + HT F+C+ C K FC R ++ +H V + KC C T
Sbjct: 169 SNRHTIRHTGKKCFKCKKCVKSFC------IRLHKTQHKCVYITEKS----CKCKECEKT 218
Query: 1706 NPIRKGLAAHYQKRHDIDAYYT--HCLAASRTISDKPNKVIIPSPPKDDSPQLSEELRRA 1763
L H ++ H D Y C A + +S II + K
Sbjct: 219 FHWSSTLTNH-KEIHTEDKPYKCEECGKAFKQLSTLTTHKIICAKEKI------------ 265
Query: 1764 VEKKKCSLCSFQSFSKKGIVSHYMKRHPGVFPKK-QHASKLGGYFTAVYADEH----EKP 1818
KC C ++F ++ + + H G P K + K + + + + EKP
Sbjct: 266 ---YKCEECG-KAFLWSSTLTRHKRIHTGEKPYKCEECGKAFSHSSTLAKHKRIHTGEKP 321
Query: 1819 TLMEEEERGNFEKAEVEGEAQEIEW--LPFRCIKCFKLSFSTAELLCMHYTDHHSRDLKR 1876
EE + F ++ + + I P++C +C K +FS + L H H
Sbjct: 322 YKCEECGKA-FSRSSTLAKHKRIHTGEKPYKCKECGK-AFSNSSTLANHKITH------- 372
Query: 1877 DFIILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHNEEFQKRAKRQE-----RRKQL 1931
+ Y+CK CD + + LT H IH E K K +E R
Sbjct: 373 ----------TEEKPYKCKECDKAFKRLSTLTKHKIIHAGE--KLYKCEECGKAFNRSSN 420
Query: 1932 LSKQKYADGAFADFKQE---RPFGHLEEVPKIKE--RKVVGYKCKFCVEVHPTLRAICNH 1986
L+ K+ +K E + F + K K + +KCK C + + H
Sbjct: 421 LTIHKFIHTGEKPYKCEECGKAFNWSSSLTKHKRFHTREKPFKCKECGKAFIWSSTLTRH 480
Query: 1987 LRKHVQYGNVP-AVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNL--DRH 2043
R H G P K R + T E Y + C AFR +L ++H
Sbjct: 481 KRIHT--GEKPYKCEECGKAFRQSSTLTKHKIIHTGEKPYKFEECG--KAFRQSLTLNKH 536
Query: 2044 MQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWC--------SFSTMTI 2095
+ H KP++CK C S L TH + HAG+ YKC C S ST I
Sbjct: 537 -KIIHSREKPYKCKECGKAFKQFSTLTTHKI-IHAGKKLYKCEECGKAFNHSSSLSTHKI 594
Query: 2096 SQLKEHSLKVH--GKALTLPRPRIVSLLSSHSH-HSSQKATPAEEVED--SNDSSYSEPP 2150
E S K GKA S L H H+ +K EE S+ S+ ++
Sbjct: 595 IHTGEKSYKCEECGKAFLWS-----STLRRHKRIHTGEKPYKCEECGKAFSHSSALAKHK 649
Query: 2151 DVQQQLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHY 2210
+ Y+ + S S + + TE+K C+ C+ + + ++ +H
Sbjct: 650 RIHTGEKPYKCKECGKAFSNSSTLA-NHKITHTEEKP---YKCKECDKTFKRLSTLTKH- 704
Query: 2211 RDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMI 2270
+ H G+KL+KC++C S T+H G K +C C + ++
Sbjct: 705 KIIHAGEKLYKCEECGKAFNRSSNLTIH------KFIHTGEKPYKCEECGKAFNWSSSLT 758
Query: 2271 DHIVLHREERVVPIEVC------RSKLSKYLQ----GVVFRCDKCTFTCSSDESLQQHIE 2320
H +H E+ + C S L+++ + ++C++C S +L +H
Sbjct: 759 KHKRIHTREKPFKCKECGKAFIWSSTLTRHKRIHTGEKPYKCEECGKAFSRSSTLTKHKT 818
Query: 2321 KHNELKPYKCQLCYYETKHTEELDSH--------LRDEHKVSRNFELVGRVNLDQLEQMK 2372
H KPYKC+ C KH+ L H L + + F + ++ K
Sbjct: 819 IHTGEKPYKCKECGKAFKHSSALAKHKIIHAGEKLYKCEECGKAFNQSSNLTTHKIIHTK 878
Query: 2373 EKMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERH 2432
EK S S++ DK +S ++H EK + CE CG+AFSQ S H
Sbjct: 879 EK--PSKSEECDKAFIWSS--------TLTEHKRIHTREKTYKCEECGKAFSQPSHLTTH 928
Query: 2433 VLRH 2436
H
Sbjct: 929 KRMH 932
Score = 112 bits (279), Expect = 6e-24
Identities = 130/605 (21%), Positives = 209/605 (34%), Gaps = 146/605 (24%)
Query: 1845 PFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQST 1904
P++C +C K +FS + L H H G P Y+CK C ++
Sbjct: 629 PYKCEECGK-AFSHSSALAKHKRIH-----------TGEKP------YKCKECGKAFSNS 670
Query: 1905 AELTSHLNIHNEEFQKRAKRQER---RKQLLSKQKYADGAFADFKQERPFGHLEEVPKIK 1961
+ L +H H EE + K ++ R L+K K +K E +
Sbjct: 671 STLANHKITHTEEKPYKCKECDKTFKRLSTLTKHKIIHAGEKLYKCEECGKAFNRSSNLT 730
Query: 1962 ERKVVG-----YKCKFCVEVHPTLRAICNHLRKHVQYGNVPAVSAAV-----KGLRSHER 2011
K + YKC+ C + ++ H R H + L H+R
Sbjct: 731 IHKFIHTGEKPYKCEECGKAFNWSSSLTKHKRIHTREKPFKCKECGKAFIWSSTLTRHKR 790
Query: 2012 SHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKT 2071
H T E Y C+ C + L +H H G KP++CK C ++S L
Sbjct: 791 IH------TGEKPYKCEECGKAFSRSSTLTKHKTIHTGE-KPYKCKECGKAFKHSSALAK 843
Query: 2072 HILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVHGKALTLPRPRIVSLLSSHSHHSSQK 2131
H + HAGE YKC C + S L H + H+ +K
Sbjct: 844 HKI-IHAGEKLYKCEECGKAFNQSSNLTTHKII----------------------HTKEK 880
Query: 2132 ATPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVL 2191
+ +EE + + + ++ + R+ T +KT
Sbjct: 881 PSKSEECDKA-----------------FIWSSTLTEHKRIH----------TREKT---Y 910
Query: 2192 HCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGP 2251
CE C + + H R H G+K +KC++C S T H + G
Sbjct: 911 KCEECGKAFSQPSHLTTHKR-MHTGEKPYKCEECGKAFSQSSTLTTH------KIIHTGE 963
Query: 2252 KDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRCDKCTFTCSS 2311
K +C C + + +H ++H E+ ++C++C S
Sbjct: 964 KPYKCEECGKAFRKSSTLTEHKIIHTGEKP------------------YKCEECGKAFSQ 1005
Query: 2312 DESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFELVGRVNLDQLEQM 2371
+L +H H KPYKC+ C + +L +H + H + + + E+
Sbjct: 1006 SSTLTRHTRMHTGEKPYKCEECGKAFNRSSKLTTH-KIIHTGEKPY---------KCEEC 1055
Query: 2372 KEKMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWER 2431
+ SSS+ + H EK + CE CG+AFSQ S R
Sbjct: 1056 GKAFISSST--------------------LNGHKRIHTREKPYKCEECGKAFSQSSTLTR 1095
Query: 2432 HVLRH 2436
H H
Sbjct: 1096 HKRLH 1100
Score = 41.6 bits (96), Expect = 0.010
Identities = 120/608 (19%), Positives = 200/608 (32%), Gaps = 104/608 (17%)
Query: 1439 EQEAECPEDARLSPEKSLQLASANPAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPGMKV 1498
E+ +C E + S PY+C C ++N L H
Sbjct: 627 EKPYKCEECGKAFSHSSALAKHKRIHTGEKPYKCKECGKAFSNSSTLANH---------- 676
Query: 1499 KAADFAQDIDINPGAVYKCRHCPYINTRIHGVLTHYQKRHPSIKV-TAEDFVHDVEQSAD 1557
I YKC+ C R+ LT ++ H K+ E+ +S++
Sbjct: 677 -------KITHTEEKPYKCKECDKTFKRL-STLTKHKIIHAGEKLYKCEECGKAFNRSSN 728
Query: 1558 ISQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFDVFSQSPPKL-- 1615
++ + T G Y+C+ C L H + + F +
Sbjct: 729 LTIHKFIHT------GEKPYKCEECGKAFNWSSSLTKHKRIHTREKPFKCKECGKAFIWS 782
Query: 1616 -PVPLEPEMTTEVSPSQVSITEEEVGEEPVSTSHFSTSHLVSHT---VFRCQLCKYFCST 1671
+ + T P + EE G+ S S T H HT ++C+ C
Sbjct: 783 STLTRHKRIHTGEKPYKC----EECGKA-FSRSSTLTKHKTIHTGEKPYKCKECGKAFKH 837
Query: 1672 RKGIARHYRIKHNNVRAQPEGKNNLFKCALCAYTNPIRKGLAAHYQKRHDIDAYYTHCLA 1731
+A+H +I H + L+KC C L H +T
Sbjct: 838 SSALAKH-KIIHAGEK--------LYKCEECGKAFNQSSNLTTH-------KIIHT---- 877
Query: 1732 ASRTISDKPNKVIIPSPPKDDSPQLSEELRRAVEKK--KCSLCSFQSFSKKGIVSHYMKR 1789
+KP+K S L+E R +K KC C ++FS+ ++ + +
Sbjct: 878 -----KEKPSKSEECDKAFIWSSTLTEHKRIHTREKTYKCEECG-KAFSQPSHLTTHKRM 931
Query: 1790 HPGVFPKK-----QHASKLGGYFTAVYADEHEKPTLMEEEERGNFEKAEVEGEAQEIEW- 1843
H G P K + S+ T EKP EE + F K+ E + I
Sbjct: 932 HTGEKPYKCEECGKAFSQSSTLTTHKIIHTGEKPYKCEECGKA-FRKSSTLTEHKIIHTG 990
Query: 1844 -LPFRCIKCFKLSFSTAELLCMHYTDH-----------------HSRDLKRDFIILGNGP 1885
P++C +C K +FS + L H H S+ I G P
Sbjct: 991 EKPYKCEECGK-AFSQSSTLTRHTRMHTGEKPYKCEECGKAFNRSSKLTTHKIIHTGEKP 1049
Query: 1886 RLQNSTYQCKHCDSKLQSTAELTSHLNIHNEEFQKRAKRQER---RKQLLSKQKYADGAF 1942
Y+C+ C S++ L H IH E + + + + L++ K
Sbjct: 1050 ------YKCEECGKAFISSSTLNGHKRIHTREKPYKCEECGKAFSQSSTLTRHKRLHTGE 1103
Query: 1943 ADFKQERPFGHLEEVPKIKERKVVG-----YKCKFCVEVHPTLRAICNHLRKHVQYGNVP 1997
+K +E + + K++ YKC+ C + + NH + H +P
Sbjct: 1104 KPYKCGECGKAFKESSALTKHKIIHTGEKPYKCEKCGKAFNQSSILTNHKKIHTITPVIP 1163
Query: 1998 AVSAAVKG 2005
+ A G
Sbjct: 1164 LLWEAEAG 1171
Score = 36.6 bits (83), Expect = 0.32
Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C H ++++H + IH K YKC+EC S L HK+ HTG
Sbjct: 294 YKCEECGKAFSHSSTLAKH-KRIHTGEKP--YKCEECGKAFSRSSTLAKHKRIHTG 346
Score = 35.4 bits (80), Expect = 0.71
Identities = 23/65 (35%), Positives = 32/65 (49%), Gaps = 6/65 (9%)
Query: 433 RRFMNR---FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHK 489
+RF R F+C C + +++RH + IH K YKC+EC + S L HK
Sbjct: 453 KRFHTREKPFKCKECGKAFIWSSTLTRH-KRIHTGEKP--YKCEECGKAFRQSSTLTKHK 509
Query: 490 QCHTG 494
HTG
Sbjct: 510 IIHTG 514
Score = 35.0 bits (79), Expect = 0.93
Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C + +++RH + IH K YKC+EC S L HK+ HTG
Sbjct: 266 YKCEECGKAFLWSSTLTRH-KRIHTGEKP--YKCEECGKAFSHSSTLAKHKRIHTG 318
Score = 34.7 bits (78), Expect = 1.2
Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 10/75 (13%)
Query: 420 DGNKLLETKGIPFRRFMNRFQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTC 479
+G+K + T+ P++ C C +++RH + +H K YKC EC
Sbjct: 1066 NGHKRIHTREKPYK-------CEECGKAFSQSSTLTRH-KRLHTGEKP--YKCGECGKAF 1115
Query: 480 KSSLKLGAHKQCHTG 494
K S L HK HTG
Sbjct: 1116 KESSALTKHKIIHTG 1130
Score = 34.3 bits (77), Expect = 1.6
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C + ++ RH + IH K YKC+EC S L HK+ HTG
Sbjct: 602 YKCEECGKAFLWSSTLRRH-KRIHTGEKP--YKCEECGKAFSHSSALAKHKRIHTG 654
Score = 34.3 bits (77), Expect = 1.6
Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
F+C C + +++RH + IH K YKC+EC S L HK HTG
Sbjct: 770 FKCKECGKAFIWSSTLTRH-KRIHTGEKP--YKCEECGKAFSRSSTLTKHKTIHTG 822
Score = 33.1 bits (74), Expect = 3.5
Identities = 19/56 (33%), Positives = 26/56 (46%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C +++RH +H K YKC+EC S KL HK HTG
Sbjct: 994 YKCEECGKAFSQSSTLTRHTR-MHTGEKP--YKCEECGKAFNRSSKLTTHKIIHTG 1046
Score = 32.7 bits (73), Expect = 4.6
Identities = 18/55 (32%), Positives = 27/55 (49%), Gaps = 3/55 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHT 493
++C C H ++++H + IH K +YKC+EC S L HK HT
Sbjct: 826 YKCKECGKAFKHSSALAKH-KIIHAGEK--LYKCEECGKAFNQSSNLTTHKIIHT 877
Score = 32.0 bits (71), Expect = 7.9
Identities = 18/55 (32%), Positives = 26/55 (47%), Gaps = 3/55 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHT 493
++C C H ++++H + IH K YKC EC +S L HK HT
Sbjct: 630 YKCEECGKAFSHSSALAKH-KRIHTGEKP--YKCKECGKAFSNSSTLANHKITHT 681
>gi|157676340 zinc finger protein 142 [Homo sapiens]
Length = 1687
Score = 129 bits (323), Expect = 5e-29
Identities = 116/498 (23%), Positives = 183/498 (36%), Gaps = 83/498 (16%)
Query: 1954 LEEVPKIKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVPAVSAAVK-GLRSHERS 2012
+++ ++K V ++C FC + H +H G +P S G S R
Sbjct: 1186 MQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSSCPQTFGTNSKLRL 1245
Query: 2013 HLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTH 2072
H L + + + C C + RH++ RH+ + H F C C + S + LK H
Sbjct: 1246 H-RLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETALKQH 1304
Query: 2073 ILKAH-------------AGEHAYKCSWCSFSTMTISQLKEHSLKVHGKA-LTLPRPRIV 2118
L+ H E CS C + + L+ H+ K H + +
Sbjct: 1305 ALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQHPRLECGACQEAFP 1364
Query: 2119 SLLSSHSHHSSQKATPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSG 2178
S L+ H Q + ++ D ++ V+ L ++ + A
Sbjct: 1365 SRLALDEHRRQQHFSHRCQLCDF--AARERVGLVKHYLEQHEETSAA-----------VA 1411
Query: 2179 AAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMH 2238
A+ G + LHC FC+F+ + Q + H+ HGG +L+KC DC++ T + T H
Sbjct: 1412 ASDGDGDAGQPPLHCPFCDFTCRH-QLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWH 1470
Query: 2239 VEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGV 2298
G K C LC Y + H+ +H+EER KYL
Sbjct: 1471 SRI------HTGEKPYHCHLCPYACADPSRLKYHMRIHKEER------------KYL--- 1509
Query: 2299 VFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFE 2358
C +C + C L+ H+ KH LKPY+C C Y T + L H H+ +R F
Sbjct: 1510 ---CPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALRVHQETRHREARAFM 1566
Query: 2359 LVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPCEF 2418
E+ + R L+R H + K + C
Sbjct: 1567 C---------------------------EQCGKAFKTRFLLR--THLRKHSEAKPYVCNV 1597
Query: 2419 CGRAFSQGSEWERHVLRH 2436
C RAF + H L H
Sbjct: 1598 CHRAFRWAAGLRHHALTH 1615
Score = 102 bits (255), Expect = 4e-21
Identities = 108/433 (24%), Positives = 163/433 (37%), Gaps = 54/433 (12%)
Query: 2025 YSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYK 2084
+ C C R +L H+ H +C C + S+LKTH+L+ GE A+
Sbjct: 163 HMCPECKRCFKKRTHLVEHLHLHFPDPS-LQCPNCQKFFTSKSKLKTHLLR-ELGEKAHH 220
Query: 2085 CSWCSFSTMTISQLKEHSLKVHGKAL-----TLPRP------RIVSLLSSH--SHHSSQK 2131
C C +S + + L H +H T P R+ L H SH ++
Sbjct: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
Query: 2132 ATPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARN-NSRVSPVPLSGAAAGTEQ---KT 2187
A P SY+ P D + + H + R R P+ A A + K+
Sbjct: 281 AEPLPLRCFQEGCSYAAP-DRKAFIKHLKETHGVRAVECRHHSCPMLFATAEAMEAHHKS 339
Query: 2188 EAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVP 2247
HC C+F+ R+H + H G + +C C F T A+ HV H+
Sbjct: 340 HYAFHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGKMHAH-- 397
Query: 2248 EEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRCDKCTF 2307
K +CP C + T +KR +I H++LH E+ +C+ C F
Sbjct: 398 ---EKIHQCPECNFATAHKRVLIRHMLLHTGEKP------------------HKCELCDF 436
Query: 2308 TCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFEL----VGRV 2363
TC L +H+ H+ K Y C C Y TK L H+R +H ++
Sbjct: 437 TCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMR-KHAGDLRYQCNQCSYRCH 495
Query: 2364 NLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAF 2423
DQL K + + S E K E ++ M H +PC +C
Sbjct: 496 RADQLSSHKLRHQGKSLMCEVCAFACKRKYELQKHMASQHHPG--TPAPLYPCHYC---- 549
Query: 2424 SQGSEWERHVLRH 2436
S S ++ VL H
Sbjct: 550 SYQSRHKQAVLSH 562
Score = 97.8 bits (242), Expect = 1e-19
Identities = 111/482 (23%), Positives = 174/482 (36%), Gaps = 71/482 (14%)
Query: 1997 PAVSAAVKGLRSHERSHLALAMFTREDK--YSCQYCSFVSAFRHNLDRHMQTHHGHHKPF 2054
P + A LR H++ A R + C C F + +H + H KP
Sbjct: 1141 PFTAPAATALRLHQKRRHPTAAPARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPH 1200
Query: 2055 RCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVHGKALTLPR 2114
+C C F ++ RL+ H + H G CS C + T S+L+ H L+VH K T
Sbjct: 1201 QCPFCDFSTTRRYRLEAHQSR-HTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFC 1259
Query: 2115 PRIVSLLSSHSHH-------SSQKATPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARN 2167
P + S + H S + TPA SE AL ++
Sbjct: 1260 P--LCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSE-------------TALKQH 1304
Query: 2168 NSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSF 2227
R P P A + TE LHC C S+R H R +H +C C
Sbjct: 1305 ALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQH---PRLECGACQE 1361
Query: 2228 YTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEV- 2286
+ A H H + RC LC + + + ++ H + EE +
Sbjct: 1362 AFPSRLALDEHRRQQHFSH--------RCQLCDFAARERVGLVKHYLEQHEETSAAVAAS 1413
Query: 2287 -------------------CRSKL--SKYLQGV----VFRCDKCTFTCSSDESLQQHIEK 2321
CR +L +++G +++C C ++ + + + H
Sbjct: 1414 DGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRI 1473
Query: 2322 HNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNF---ELVGRVN-LDQLEQMKEKMES 2377
H KPY C LC Y L H+R HK R + E + ++QL+ K
Sbjct: 1474 HTGEKPYHCHLCPYACADPSRLKYHMRI-HKEERKYLCPECGYKCKWVNQLKYHMTKHTG 1532
Query: 2378 SSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRHG 2437
+ E ++A+ + + + H A + F CE CG+AF H+ +H
Sbjct: 1533 LKPYQCPECEYCTNRADALRVHQETRHREA----RAFMCEQCGKAFKTRFLLRTHLRKHS 1588
Query: 2438 MA 2439
A
Sbjct: 1589 EA 1590
Score = 85.9 bits (211), Expect = 5e-16
Identities = 98/441 (22%), Positives = 157/441 (35%), Gaps = 86/441 (19%)
Query: 1969 KCKFCVEVHPTLRAICNHLRKH-----VQYGNVPAVSAAVKGLRSHERSHLALAMFTRED 2023
+CK C + L HL H +Q N + L++H L E
Sbjct: 167 ECKRCFKKRTHL---VEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHLLRELG------EK 217
Query: 2024 KYSCQYCSFVSAFRHNLDRHMQTHHG-----HHKPFRCKLCSFKSSYNSRLKTHILKAHA 2078
+ C C + + R+ L+RHM + H + + C +C + + LK H LK+H
Sbjct: 218 AHHCPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEH-LKSHT 276
Query: 2079 GEHA-----YKC--SWCSFSTMTISQLKEHSLKVHGKALTLPRPRIVSLLSSHSHHSSQK 2131
A +C CS++ +H + HG V + H
Sbjct: 277 AAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHG----------VRAVECRHHSCPML 326
Query: 2132 ATPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVL 2191
AE +E + S Y+ H A +N + G+E+ L
Sbjct: 327 FATAEAMEAHHKSHYAF---------HCPHCDFACSNKHLFRKHKKQGHPGSEE-----L 372
Query: 2192 HCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHV-----EAGHSA- 2245
C FC F++ + + H H +K+ +C +C+F T K H+ E H
Sbjct: 373 RCTFCPFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCE 432
Query: 2246 ----------------VPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCR- 2288
+ KD C C Y TK+K + H+ H + C
Sbjct: 433 LCDFTCRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSY 492
Query: 2289 -----SKLSKYL---QGVVFRCDKCTFTCSSDESLQQHI-EKHNELKP---YKCQLCYYE 2336
+LS + QG C+ C F C LQ+H+ +H+ P Y C C Y+
Sbjct: 493 RCHRADQLSSHKLRHQGKSLMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQ 552
Query: 2337 TKHTEELDSHLRDEHKVSRNF 2357
++H + + SH +H R F
Sbjct: 553 SRHKQAVLSHENCKHTRLREF 573
Score = 76.6 bits (187), Expect = 3e-13
Identities = 138/731 (18%), Positives = 235/731 (32%), Gaps = 126/731 (17%)
Query: 1575 GAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFDVFSQSPPKLPVPLEPEMTTEVSPSQVSI 1634
G + C CP+ L + H + + P+ + P + +P +
Sbjct: 1024 GKFHCNSCPFLCSRLSSITSHVAEGCRGGRGGGGKRGTPQTQPDVSPLSNGDSAPPKNGS 1083
Query: 1635 TEEEVGEEPVSTSHFSTSHLVSHTVFRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKN 1694
TE G+ F C C + C + + H +R P ++
Sbjct: 1084 TESSSGDGDTVLVQKQKG-----ARFSCPTCPFSCQQERALRTH------QIRGCPLEES 1132
Query: 1695 NLFKCALCAYTNPIRKGLAAHYQKRHDIDA----YYTHCLAASRTISDKPNKVIIPSPPK 1750
C+LC +T P L H ++RH A H + K ++ +
Sbjct: 1133 GELHCSLCPFTAPAATALRLHQKRRHPTAAPARGPRPHLQCGDCGFTCKQSRCM------ 1186
Query: 1751 DDSPQLSEELRRAVEKKKCSLCSFQSFSKKGIVSHYMKRHPGV--FPKKQHASKLG--GY 1806
+L E V+ +C C F + + + +H RH G+ P G
Sbjct: 1187 QQHRRLKHE---GVKPHQCPFCDFSTTRRYRLEAH-QSRHTGIGRIPCSSCPQTFGTNSK 1242
Query: 1807 FTAVYADEHEK-PT-LMEEEERGNFEKAEVEGEAQEI-EWLP-FRCIKCFKLSFSTAELL 1862
H+K PT + + + ++ + P F C +C + FS+ L
Sbjct: 1243 LRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQC-EAQFSSETAL 1301
Query: 1863 CMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHNEEFQKRA 1922
H H + G+ C C S A L H + + A
Sbjct: 1302 KQHALRRHPEPAQP---APGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQHPRLECGA 1358
Query: 1923 KRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVPKIKERKVVGYKCKFCVEVHPTLRA 1982
++ +L A + ++++ F H ++ R+ VG + + T A
Sbjct: 1359 CQEAFPSRL---------ALDEHRRQQHFSHRCQLCDFAARERVGLVKHYLEQHEETSAA 1409
Query: 1983 I--------CNHLRKHVQYGNVPAVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVS 2034
+ H + + V L H + H + Y C C++ +
Sbjct: 1410 VAASDGDGDAGQPPLHCPFCDFTCRHQLV--LDHHVKGHGGTRL------YKCTDCAYST 1461
Query: 2035 AFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMT 2094
R + H + H G KP+ C LC + + SRLK H ++ H E Y C C +
Sbjct: 1462 KNRQKITWHSRIHTG-EKPYHCHLCPYACADPSRLKYH-MRIHKEERKYLCPECGYKCKW 1519
Query: 2095 ISQLKEHSLKVHGKALTLPRPRIVSLLSSHSHHSSQKATPAEEVEDSNDSSYSEPPDVQQ 2154
++QLK H K H+ K E E ++ ++ V Q
Sbjct: 1520 VNQLKYHMTK----------------------HTGLKPYQCPECEYC--TNRADALRVHQ 1555
Query: 2155 QLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFC--EFSSGYIQSIRRHYRD 2212
+ H ++ A CE C F + ++ +R H R
Sbjct: 1556 ETRHREARAFM---------------------------CEQCGKAFKTRFL--LRTHLR- 1585
Query: 2213 KHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDH 2272
KH K + C C AF H A+ C LC Y K K ++ H
Sbjct: 1586 KHSEAKPYVCNVC------HRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKH 1639
Query: 2273 IVLHREERVVP 2283
+ H ++ P
Sbjct: 1640 VRRHHPDQADP 1650
Score = 73.6 bits (179), Expect = 2e-12
Identities = 96/471 (20%), Positives = 162/471 (34%), Gaps = 93/471 (19%)
Query: 1848 CIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQSTAEL 1907
C +CFK E L +H+ D + QC +C S ++L
Sbjct: 168 CKRCFKKRTHLVEHLHLHFPD---------------------PSLQCPNCQKFFTSKSKL 206
Query: 1908 TSHLNIHNEE--------FQKRAKRQERRKQLLSKQKYADGAFAD----------FKQER 1949
+HL E +R + + S + ++D F+ +
Sbjct: 207 KTHLLRELGEKAHHCPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQ 266
Query: 1950 PFG-HLEEVPKIKERKVVGYKC--KFCVEVHPTLRAICNHLRK-------HVQYGNVPAV 1999
HL+ + + +C + C P +A HL++ ++ + P +
Sbjct: 267 ALKEHLKSHTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPML 326
Query: 2000 SAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLC 2059
A + + +H +SH A + C +C F + +H +H + H + RC C
Sbjct: 327 FATAEAMEAHHKSHYA---------FHCPHCDFACSNKHLFRKHKKQGHPGSEELRCTFC 377
Query: 2060 SFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSL-----KVHGKALTLPR 2114
F + + H+ K HA E ++C C+F+T L H L K H L
Sbjct: 378 PFATFNPVAYQDHVGKMHAHEKIHQCPECNFATAHKRVLIRHMLLHTGEKPHKCELCDFT 437
Query: 2115 PRIVSLLSSHS-HHSSQKATPAEEVEDSNDSSY-------SEPPDVQQQLNH-----YQS 2161
R VS LS H HS+ K E + D++ Q N +++
Sbjct: 438 CRDVSYLSKHMLTHSNTKDYMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSYRCHRA 497
Query: 2162 AALARNNSRVSPVPL--SGAAAGTEQKTEAVLH---------------CEFCEFSSGYIQ 2204
L+ + R L A ++K E H C +C + S + Q
Sbjct: 498 DQLSSHKLRHQGKSLMCEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQ 557
Query: 2205 SIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLR 2255
++ H KH + F C C + T + H H VP + LR
Sbjct: 558 AVLSHENCKHTRLREFHCALCDYRTFSNTTLLFHKRKAHGYVPGDQAWQLR 608
Score = 65.9 bits (159), Expect = 5e-10
Identities = 127/645 (19%), Positives = 204/645 (31%), Gaps = 158/645 (24%)
Query: 1463 PAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPGMKVKAADFAQDIDINPGAVYKCRHCPY 1522
P S C++C L H ++HP P +C C +
Sbjct: 1128 PLEESGELHCSLCPFTAPAATALRLHQKRRHPTAAPARG---------PRPHLQCGDCGF 1178
Query: 1523 INTRIHGVLTHYQKRHPSIKVTAEDFVHDVEQSADISQNDVEETSRIFKQGYGAYRCKLC 1582
+ + H + +H +K F ++ E + G G C C
Sbjct: 1179 TCKQSRCMQQHRRLKHEGVKPHQCPFC-----DFSTTRRYRLEAHQSRHTGIGRIPCSSC 1233
Query: 1583 PYTHGTLEKLKIHYEKYHNQPEFDVFSQSPPKLPVPLEPEMTTEVSPSQVSITEEEVGEE 1642
P T GT KL++H + H+ K P P + + IT
Sbjct: 1234 PQTFGTNSKLRLHRLRVHD------------KTPTHFCP-LCDYSGYLRHDITRH----- 1275
Query: 1643 PVSTSHFSTSHLVSHTVFRCQLCKYFCSTRKGIARHYRIKHNNVRAQP------EGKNNL 1696
V++ H T F C C+ S+ + +H +H AQP E
Sbjct: 1276 -VNSCHQGTP------AFACSQCEAQFSSETALKQHALRRHPEP-AQPAPGSPAETTEGP 1327
Query: 1697 FKCALCAYTNPIRKGLAAHYQKRHDIDAYYTHCLAASRTISDKPNKVIIPSPPKDDSPQL 1756
C+ C P L H +K+H C A P+++ L
Sbjct: 1328 LHCSRCGLLCPSPASLRGHTRKQHP----RLECGACQEAF---PSRLA-----------L 1369
Query: 1757 SEELRRAVEKKKCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGYFTAVYADEHE 1816
E R+ +C LC F + + G+V HY+++H
Sbjct: 1370 DEHRRQQHFSHRCQLCDFAARERVGLVKHYLEQH-------------------------- 1403
Query: 1817 KPTLMEEEERGNFEKAEVEGEAQEIEWLPFRCIKCFKLSFSTAELLCMHYT--DHHSRDL 1874
EE ++ +G+A + P C C + C H DHH +
Sbjct: 1404 ------EETSAAVAASDGDGDAGQP---PLHCPFC--------DFTCRHQLVLDHHVKG- 1445
Query: 1875 KRDFIILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHNEE----------------- 1917
G RL Y+C C ++ ++T H IH E
Sbjct: 1446 -------HGGTRL----YKCTDCAYSTKNRQKITWHSRIHTGEKPYHCHLCPYACADPSR 1494
Query: 1918 --FQKRAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVPKIKERKVVGYKCKFCVE 1975
+ R ++ER K L + Y K H+ + +K + +C++C
Sbjct: 1495 LKYHMRIHKEER-KYLCPECGYKCKWVNQLKY-----HMTKHTGLKPYQCP--ECEYCTN 1546
Query: 1976 VHPTLRAICNHLRKHVQYGNVPAVSAAVKG---LRSHERSHLALAMFTREDKYSCQYCSF 2032
LR + + A K LR+H R H + Y C C
Sbjct: 1547 RADALRVHQETRHREARAFMCEQCGKAFKTRFLLRTHLRKH------SEAKPYVCNVCHR 1600
Query: 2033 VSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAH 2077
+ L H TH H PF C+LC++K+ ++ H+ + H
Sbjct: 1601 AFRWAAGLRHHALTHTDRH-PFFCRLCNYKAKQKFQVVKHVRRHH 1644
Score = 64.3 bits (155), Expect = 1e-09
Identities = 93/474 (19%), Positives = 154/474 (32%), Gaps = 105/474 (22%)
Query: 1760 LRRAVEKKK-CSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGYFTAVYADEHEKP 1818
LR EK C LC + + + + H H + + Y+D + P
Sbjct: 211 LRELGEKAHHCPLCHYSAVERNALNRHMASMHEDI--------------SNFYSDTYACP 256
Query: 1819 TLMEEEERGNFEKAEVEGE--AQEIEWLPFRC---------------IKCFKLSFSTAEL 1861
EE K ++ A E LP RC IK K + +
Sbjct: 257 VCREEFRLSQALKEHLKSHTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAV 316
Query: 1862 LCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHNEEFQKR 1921
C H HS + + + C HCD + HL F+K
Sbjct: 317 ECRH----HSCPMLFATAEAMEAHHKSHYAFHCPHCDFACSN-----KHL------FRKH 361
Query: 1922 AKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVPKIKERKVVGYKCKFCVEVHPTLR 1981
K+ + L F F P + + V K+ + + ++C C R
Sbjct: 362 KKQGHPGSEELRC------TFCPFATFNPVAYQDHVGKMHAHEKI-HQCPECNFATAHKR 414
Query: 1982 AICNHLRKHVQYGNVPAVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLD 2041
+ H+ H T E + C+ C F L
Sbjct: 415 VLIRHMLLH-----------------------------TGEKPHKCELCDFTCRDVSYLS 445
Query: 2042 RHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEH 2101
+HM TH + K + C C + + + L+ H+ K HAG+ Y+C+ CS+ QL H
Sbjct: 446 KHMLTH-SNTKDYMCTECGYVTKWKHYLRVHMRK-HAGDLRYQCNQCSYRCHRADQLSSH 503
Query: 2102 SLKVHGKALTLPRPRIVSLLSSHSHHSSQKATPAEEVEDSNDSSYSEPPDVQQQLNHYQS 2161
L+ GK+L V + + QK ++ + Y P + ++
Sbjct: 504 KLRHQGKSLMCE----VCAFACKRKYELQKHMASQHHPGTPAPLY--PCHYCSYQSRHKQ 557
Query: 2162 AALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHG 2215
A L+ N + + + HC C++ + ++ H R HG
Sbjct: 558 AVLSHENCKHTRL--------------REFHCALCDYRTFSNTTLLFHKRKAHG 597
Score = 58.9 bits (141), Expect = 6e-08
Identities = 106/532 (19%), Positives = 176/532 (33%), Gaps = 111/532 (20%)
Query: 1652 SHLVSHT-------VFRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCALCAY 1704
+HLV H +C C+ F +++ + H +R E ++ C LC Y
Sbjct: 176 THLVEHLHLHFPDPSLQCPNCQKFFTSKSKLKTHL------LRELGEKAHH---CPLCHY 226
Query: 1705 TNPIRKGLAAHYQKRH-DIDAYYTHCLAASRTISDKPNKVIIPSPPKDDSPQLSEELRRA 1763
+ R L H H DI +Y+ A P + +LS+ L+
Sbjct: 227 SAVERNALNRHMASMHEDISNFYSDTYAC---------------PVCREEFRLSQALKEH 271
Query: 1764 VEKKKCSL-------------CSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGYFTAV 1810
++ + CS+ + +K + H + H + +H S + TA
Sbjct: 272 LKSHTAAAAAEPLPLRCFQEGCSYAAPDRKAFIKHLKETHGVRAVECRHHSCPMLFATAE 331
Query: 1811 YADEHEKPTLMEE--------EERGNFEKAEVEGEAQEIEWLPFRCIKCFKLSFSTAELL 1862
+ H K + F K + +G E RC C +F+
Sbjct: 332 AMEAHHKSHYAFHCPHCDFACSNKHLFRKHKKQGHPGSEE---LRCTFCPFATFNPVA-- 386
Query: 1863 CMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHNEEFQKRA 1922
Y DH + + I +QC C+ L H+ +H E +
Sbjct: 387 ---YQDHVGKMHAHEKI------------HQCPECNFATAHKRVLIRHMLLHTGEKPHKC 431
Query: 1923 KRQE---RRKQLLSKQKYADGAFADFKQERPFGHLEEVPKIKERKVVGYKCKFCVEVHPT 1979
+ + R LSK D Y C C V
Sbjct: 432 ELCDFTCRDVSYLSKHMLTHSNTKD-----------------------YMCTECGYVTKW 468
Query: 1980 LRAICNHLRKHVQYGNVPAVSAAVKGLRSHERSHLALAMFTREDK-YSCQYCSFVSAFRH 2038
+ H+RKH G++ R H L+ + K C+ C+F ++
Sbjct: 469 KHYLRVHMRKHA--GDL-RYQCNQCSYRCHRADQLSSHKLRHQGKSLMCEVCAFACKRKY 525
Query: 2039 NLDRHMQTHHGHHKP---FRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTI 2095
L +HM + H P + C CS++S + + +H H + C+ C + T +
Sbjct: 526 ELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCDYRTFSN 585
Query: 2096 SQLKEHSLKVHGKALTLPRPRIVSL--LSSHSHHSSQKATPAEEVEDSNDSS 2145
+ L H K HG +P + L S + Q TP + E SN S
Sbjct: 586 TTLLFHKRKAHG---YVPGDQAWQLRYASQEPEGAMQGPTPPPDSEPSNQLS 634
Score = 58.9 bits (141), Expect = 6e-08
Identities = 72/371 (19%), Positives = 111/371 (29%), Gaps = 78/371 (21%)
Query: 2054 FRCKLCSFKSSYNSRLKTHILKAHAGEHAYK--CSWCSFSTMTISQLKEHSLKVHGKALT 2111
F C C F L+TH ++ E + + CS C F+ + L+ H + H A
Sbjct: 1104 FSCPTCPFSCQQERALRTHQIRGCPLEESGELHCSLCPFTAPAATALRLHQKRRHPTAAP 1163
Query: 2112 L--PRPRIVSLLSSHSHHSSQKATPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNS 2169
PRP + + S+ ++ + P Y+ A ++
Sbjct: 1164 ARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHT 1223
Query: 2170 RVSPVPLSGAAAGTEQKTEAVLH------------CEFCEFSSGYIQSIRRHYRDKHGGK 2217
+ +P S ++ LH C C++S I RH H G
Sbjct: 1224 GIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGT 1283
Query: 2218 KLFKCKDCSFYTGFKSAFTMHV----------EAGHSAVPEEGPK-----DLRCP----- 2257
F C C ++A H G A EGP L CP
Sbjct: 1284 PAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASL 1343
Query: 2258 ----------------------------------------LCLYHTKYKRNMIDHIVLHR 2277
LC + + + ++ H +
Sbjct: 1344 RGHTRKQHPRLECGACQEAFPSRLALDEHRRQQHFSHRCQLCDFAARERVGLVKHYLEQH 1403
Query: 2278 EERVVPIEVCRSKLSKYLQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYET 2337
EE V S C C FTC L H++ H + YKC C Y T
Sbjct: 1404 EE--TSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYST 1461
Query: 2338 KHTEELDSHLR 2348
K+ +++ H R
Sbjct: 1462 KNRQKITWHSR 1472
Score = 56.6 bits (135), Expect = 3e-07
Identities = 111/568 (19%), Positives = 183/568 (32%), Gaps = 112/568 (19%)
Query: 1265 LKCRQCSYTSPYFYALRKHIKKDHPALKATVTSIMRWAFLDGLIEAGYHCEWCIYSHTEP 1324
L+C C +T +++H + H +K + C +C +S T
Sbjct: 1171 LQCGDCGFTCKQSRCMQQHRRLKHEGVKP------------------HQCPFCDFSTTRR 1212
Query: 1325 NGLLLHYQRRHPEHYVDYTYMATKLWAGPDPSPPSLTMPAEAKTYRCRDCVFEAVSIWDI 1384
L H R + + L + + T+ C C + DI
Sbjct: 1213 YRLEAHQSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDI 1272
Query: 1385 TNHYQAFHPW----------AMNGDESVLLDIIKEK---DAVEKPILSSEELAGPVNCEN 1431
T H + H A E+ L + A P +E GP++C
Sbjct: 1273 TRHVNSCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSR 1332
Query: 1432 S---IPTPFPEQEAECPEDARLSPEKSLQLASANPAISS------TPYQCTVCQSEYNNL 1482
P+P + + RL + + A+ ++C +C
Sbjct: 1333 CGLLCPSPASLRGHTRKQHPRLECGACQEAFPSRLALDEHRRQQHFSHRCQLCDFAARER 1392
Query: 1483 HGLLTHYGKKHPGMKVKAADFAQDIDINPGAVYKCRHCPY--INTRIHGVLTHYQKRHPS 1540
GL+ HY ++H + AA A D D + G HCP+ R VL H+ K H
Sbjct: 1393 VGLVKHYLEQHE--ETSAAVAASDGDGDAG--QPPLHCPFCDFTCRHQLVLDHHVKGHGG 1448
Query: 1541 IKV-TAEDFVHDVEQSADISQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKY 1599
++ D + + I+ + SRI G Y C LCPY +LK H +
Sbjct: 1449 TRLYKCTDCAYSTKNRQKITWH-----SRI-HTGEKPYHCHLCPYACADPSRLKYHMRIH 1502
Query: 1600 HNQPEFDVFSQSPPKLPVPLEPEMTTEVS-PSQVSITEEEVGEEPVSTSHFSTSHLVSHT 1658
+ ++ L PE + +Q+ H+ HT
Sbjct: 1503 KEERKY-------------LCPECGYKCKWVNQLKY------------------HMTKHT 1531
Query: 1659 ---VFRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCALCAYTNPIRKGLAAH 1715
++C C+Y + + H +H RA F C C R L H
Sbjct: 1532 GLKPYQCPECEYCTNRADALRVHQETRHREARA--------FMCEQCGKAFKTRFLLRTH 1583
Query: 1716 YQKRHDIDAYYTH-CLAASRTISDKPNKVIIPSPPKDDSPQLSEELRRAVEKKKCSLCSF 1774
+K + Y + C A R + + + + D P C LC++
Sbjct: 1584 LRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHT---DRHPFF------------CRLCNY 1628
Query: 1775 QSFSKKGIVSHYMKRHPGVFPKKQHASK 1802
++ K +V H + HP Q K
Sbjct: 1629 KAKQKFQVVKHVRRHHPDQADPNQGVGK 1656
Score = 54.7 bits (130), Expect = 1e-06
Identities = 109/553 (19%), Positives = 182/553 (32%), Gaps = 95/553 (17%)
Query: 1551 DVEQSADISQNDVEETSRIFKQGYGAYRCKLC--PYTHGTLEKLKIHYEKYHNQ-PEFDV 1607
D Q A + DV + + + CK C TH +E L +H+ Q P
Sbjct: 140 DKGQGAQRLEGDVVSGTESLFKTHMCPECKRCFKKRTH-LVEHLHLHFPDPSLQCPNCQK 198
Query: 1608 FSQSPPKLPVPLEPEMTTEVSPSQV---SITEEEVGEEPVSTSHFSTSHLVSHTVFRCQL 1664
F S KL L E+ + + S E +++ H S+ S T + C +
Sbjct: 199 FFTSKSKLKTHLLRELGEKAHHCPLCHYSAVERNALNRHMASMHEDISNFYSDT-YACPV 257
Query: 1665 CKYFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCAL--CAYTNPIRKGLAAHYQKRHDI 1722
C+ + + H + A+P +C C+Y P RK H ++ H +
Sbjct: 258 CREEFRLSQALKEHLKSHTAAAAAEPLP----LRCFQEGCSYAAPDRKAFIKHLKETHGV 313
Query: 1723 DAYYTHCLAASRTISDKPNKVIIPSPPKDDSPQLSEELRRAVEKKKCSLCSFQSFSKKGI 1782
A C S P + + E ++ C C F +K
Sbjct: 314 RA--VECRHHS-------------CPMLFATAEAMEAHHKSHYAFHCPHCDFACSNKHLF 358
Query: 1783 VSHYMKRHPGVFPKKQHASKLGGYFTAVYADEHEKPTLMEEEERGNFEKAEVEGEAQEIE 1842
H + HPG + + Y D K M E+ +
Sbjct: 359 RKHKKQGHPGSEELRCTFCPFATFNPVAYQDHVGK---MHAHEKIH-------------- 401
Query: 1843 WLPFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFII-LGNGPRLQNSTYQCKHCDSKL 1901
+C + +F+TA H R L R ++ G P ++C+ CD
Sbjct: 402 -------QCPECNFATA----------HKRVLIRHMLLHTGEKP------HKCELCDFTC 438
Query: 1902 QSTAELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVPKIK 1961
+ + L+ H+ H+ D + + H V K
Sbjct: 439 RDVSYLSKHMLTHSNT--------------------KDYMCTECGYVTKWKHYLRVHMRK 478
Query: 1962 ERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVPAVSAAVKGLRSHERSHLALAMF-- 2019
+ Y+C C + +H +H + V A + + H+A
Sbjct: 479 HAGDLRYQCNQCSYRCHRADQLSSHKLRHQGKSLMCEVCAFACKRKYELQKHMASQHHPG 538
Query: 2020 TREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHA- 2078
T Y C YCS+ S + + H H + F C LC +++ N+ L H KAH
Sbjct: 539 TPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREFHCALCDYRTFSNTTLLFHKRKAHGY 598
Query: 2079 --GEHAYKCSWCS 2089
G+ A++ + S
Sbjct: 599 VPGDQAWQLRYAS 611
Score = 51.2 bits (121), Expect = 1e-05
Identities = 82/410 (20%), Positives = 134/410 (32%), Gaps = 115/410 (28%)
Query: 2025 YSCQYCSFVSAFRHNLDRHMQTH-HGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAY 2083
+ C +C F++ L+ H +T G +P C C L TH+LK
Sbjct: 836 FRCPHCPFITRREKALNLHSRTGCQGRREPLLCPECGASFKQQRGLSTHLLK-------- 887
Query: 2084 KCSWCSFSTMTISQLKEHSLKVHGKALTLPRPRIVSLLSSHSHHSSQKATPAEEVE---- 2139
KC + K L + L +P + +S S + ++E E
Sbjct: 888 KC--------PVLLRKNKGLPRPDSPIPL-QPVLPGTQASEDTESGKPPPASQEAELLLP 938
Query: 2140 -DSNDSSYSEPPDVQQQLNHYQSAAL----------ARNNSRVSPVPLSGAAAGTEQKTE 2188
D+ EP + ++ L + + A PVP +G ++ TE +
Sbjct: 939 KDAPLELPREPEETEEPLATVSGSPVPPAGNSLPTEAPKKHCFDPVPPAGNSSPTEAPKK 998
Query: 2189 AVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHV--------- 2239
L +S +++++H ++ GK F C C F S+ T HV
Sbjct: 999 HHLDPVPPAGNSSPTEALKKHRFEQ--GK--FHCNSCPFLCSRLSSITSHVAEGCRGGRG 1054
Query: 2240 -----------------EAGHSAVPEEGPKD------------------LRCPLCLYHTK 2264
G SA P+ G + CP C + +
Sbjct: 1055 GGGKRGTPQTQPDVSPLSNGDSAPPKNGSTESSSGDGDTVLVQKQKGARFSCPTCPFSCQ 1114
Query: 2265 YKRNMIDHIV---------------------------LHREERVVPIEVCRSKLSKYLQG 2297
+R + H + LH++ R R +LQ
Sbjct: 1115 QERALRTHQIRGCPLEESGELHCSLCPFTAPAATALRLHQKRRHPTAAPARGP-RPHLQ- 1172
Query: 2298 VVFRCDKCTFTCSSDESLQQHIE-KHNELKPYKCQLCYYETKHTEELDSH 2346
C C FTC +QQH KH +KP++C C + T L++H
Sbjct: 1173 ----CGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAH 1218
Score = 48.1 bits (113), Expect = 1e-04
Identities = 97/487 (19%), Positives = 149/487 (30%), Gaps = 91/487 (18%)
Query: 164 CQFCTYKSPRRARIIKHQKMYHKNNLKETTAPPPAPAPMPDPVVPPVSLQDPCKELPAEV 223
C C + +P + HQK H P APA P P + CK+
Sbjct: 1137 CSLCPFTAPAATALRLHQKRRH---------PTAAPARGPRPHLQCGDCGFTCKQSRCMQ 1187
Query: 224 VERSILESMVKPLTKSRGNFCCEWCSYQTPRRERWCDHMMKKHRSMVKILSSLRQQQEGT 283
R + VKP C +C + T RR R H Q T
Sbjct: 1188 QHRRLKHEGVKPHQ-------CPFCDFSTTRRYRLEAH-----------------QSRHT 1223
Query: 284 NLPDVPNKSAPSPTSNSTYLTMNAASREIPNTT----VSNFRGSMGNSIMRPNSSASKFS 339
+ +P S P ++ L ++ T + ++ G + + I R +S + +
Sbjct: 1224 GIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQGT 1283
Query: 340 P-MSYPQMKPKSPHNSGLVNLTERSRYGMTDMTNSSADLETNSMLNDSSSDEELNEIDSE 398
P + Q + + + L R S T L+ S S
Sbjct: 1284 PAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASL 1343
Query: 399 NGLSAMDHQTSGLSAEQLMGSDGNKLLETKGIPFRRFMNRFQCPFCPFLTMHRRSISRHI 458
G + H A Q L E + R+ +C C F R + +H
Sbjct: 1344 RGHTRKQHPRLECGACQEAFPSRLALDEHR----RQQHFSHRCQLCDFAARERVGLVKHY 1399
Query: 459 ENIHLSGKTAV-------------YKCDECPFTCKSSLKLGAHKQCHTGTTSDWDAVNSQ 505
H AV C C FTC+ L L H + H GT +
Sbjct: 1400 LEQHEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTR-----LYKC 1454
Query: 506 SESISSSLNEGVVSYESSSINGRKSGVMLDPLQQQQPPQPPPPPPPPPPSQPQPLQQPQP 565
++ S+ N +++ S G K P P P
Sbjct: 1455 TDCAYSTKNRQKITWHSRIHTGEK----------------------PYHCHLCPYACADP 1492
Query: 566 PQLQPPHQVPPQPQTQPPP---------TQQPQPPTQAAPLHPYKCTMCNYSTTTLKGLR 616
+L+ ++ + + P Q T+ L PY+C C Y T LR
Sbjct: 1493 SRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGLKPYQCPECEYCTNRADALR 1552
Query: 617 VHQQHKH 623
VHQ+ +H
Sbjct: 1553 VHQETRH 1559
Score = 46.2 bits (108), Expect = 4e-04
Identities = 47/219 (21%), Positives = 74/219 (33%), Gaps = 47/219 (21%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAH--KQCHTGTT 496
F+CP CPF+T ++++ H G+ C EC + K L H K+C
Sbjct: 836 FRCPHCPFITRREKALNLH-SRTGCQGRREPLLCPECGASFKQQRGLSTHLLKKC----- 889
Query: 497 SDWDAVNSQSESISSSLNEGVVSYESSSINGRKSGVMLDP-LQQQQPPQPPPPPPPPPPS 555
V+ ++ + S + L P L Q + PPP S
Sbjct: 890 -------------------PVLLRKNKGLPRPDSPIPLQPVLPGTQASEDTESGKPPPAS 930
Query: 556 QPQPLQQPQPPQLQPPHQVPPQPQTQPPPTQQPQPPTQAAPLHPYKCTMCNYSTTTLKGL 615
Q L P+ L+ P +P T++P +P+ P L
Sbjct: 931 QEAELLLPKDAPLELPR--------EPEETEEPLATVSGSPVPP-----------AGNSL 971
Query: 616 RVHQQHKHSFCDNLPKFEGQPSSLPLENETDSHPSSSNT 654
KH F P P+ P ++ D P + N+
Sbjct: 972 PTEAPKKHCFDPVPPAGNSSPTEAPKKHHLDPVPPAGNS 1010
Score = 46.2 bits (108), Expect = 4e-04
Identities = 113/579 (19%), Positives = 183/579 (31%), Gaps = 125/579 (21%)
Query: 840 GRLYYCKHCDFNNKSARSVSTHYQRMHPYIKFSFRYILDPNDHSAVYRCLECYIDYTNFE 899
G + C C F+ + R++ TH R P + S C C
Sbjct: 1101 GARFSCPTCPFSCQQERALRTHQIRGCPL------------EESGELHCSLCPFTAPAAT 1148
Query: 900 DLQQHYGEHHPEAMNVLNFDHSDLIYRCRFCSYTSPNVRSLMPHYQRMHPTVKINNAMI- 958
L+ H HP A +C C +T R + H + H VK +
Sbjct: 1149 ALRLHQKRRHPTAAPARGPRPH---LQCGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFC 1205
Query: 959 -FSS---YVVEQQEGLNTESQTLREILNSAPKNMATSTPVARGGGLPATFNKNTPKTFTP 1014
FS+ Y +E + +T + +S P+ T++ + + TP F P
Sbjct: 1206 DFSTTRRYRLEAHQSRHTGIGRIP--CSSCPQTFGTNSKLRLHR---LRVHDKTPTHFCP 1260
Query: 1015 ECE----------NQKDPLVNTVVVYDCDVCSFASPNMHSVLVHYQKKHPE--EKASYFR 1062
C+ + + C C + ++ H ++HPE + A
Sbjct: 1261 LCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSP 1320
Query: 1063 IQKTMRMVSVDRGSALSQLSFEVGAPMSPKMSNMGSPPPPQPPPPDLSTE--------LY 1114
+ T + R L + + + + P L+ + +
Sbjct: 1321 AETTEGPLHCSRCGLLCPSPASLRGHTRKQHPRLECGACQEAFPSRLALDEHRRQQHFSH 1380
Query: 1115 YCKHCSYSNRSVVGVLVHYQKRHPEIKVTAKYIRQAPPTAAMMRGVEGPQGSPRPPAPIQ 1174
C+ C ++ R VG++ HY ++H E T+A + +G + +PP
Sbjct: 1381 RCQLCDFAARERVGLVKHYLEQHEE-------------TSAAVAASDGDGDAGQPP---- 1423
Query: 1175 QLNRSSSERDGPPVENEMFFCQHCDYGNRTVKGVLIHYQKKH---RDFKA--------NA 1223
C CD+ R + VL H+ K H R +K N
Sbjct: 1424 ------------------LHCPFCDFTCRH-QLVLDHHVKGHGGTRLYKCTDCAYSTKNR 1464
Query: 1224 DVIRQHTATIRSLCDRNQKKPASCVL-----VSPSNLE---RDKTKLRALKCRQCSYTSP 1275
I H+ +KP C L PS L+ R + R C +C Y
Sbjct: 1465 QKITWHSRI------HTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCK 1518
Query: 1276 YFYALRKHIKKDHPALKATVTSIMRWAFLDGLIEAGYHCEWCIYSHTEPNGLLLHYQRRH 1335
+ L+ H+ K H LK Y C C Y + L +H + RH
Sbjct: 1519 WVNQLKYHMTK-HTGLKP------------------YQCPECEYCTNRADALRVHQETRH 1559
Query: 1336 PEHYVDYTYMATKLWAGPDPSPPSLTMPAEAKTYRCRDC 1374
E K + L +EAK Y C C
Sbjct: 1560 REARAFMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVC 1598
Score = 44.7 bits (104), Expect = 0.001
Identities = 22/56 (39%), Positives = 30/56 (53%), Gaps = 3/56 (5%)
Query: 440 QCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTGT 495
QCP C F T H+R + RH+ +H K +KC+ C FTC+ L H H+ T
Sbjct: 402 QCPECNFATAHKRVLIRHM-LLHTGEKP--HKCELCDFTCRDVSYLSKHMLTHSNT 454
Score = 43.9 bits (102), Expect = 0.002
Identities = 88/444 (19%), Positives = 135/444 (30%), Gaps = 94/444 (21%)
Query: 1194 FCQHCDYGNRTVKGVLIHYQKKHRDFKANA----DVIRQHTATIRSLCDRNQKKPASCVL 1249
FC CDY + H H+ A A + ++ R +PA
Sbjct: 1258 FCPLCDYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETALKQHALRRHPEPAQPAP 1317
Query: 1250 VSPSNLERDKTKLRALKCRQCSYTSPYFYALRKHIKKDHPALKATVTSIMRWAFLDGLI- 1308
SP+ +T L C +C P +LR H +K HP L+ + AF L
Sbjct: 1318 GSPA-----ETTEGPLHCSRCGLLCPSPASLRGHTRKQHPRLEC---GACQEAFPSRLAL 1369
Query: 1309 -------EAGYHCEWCIYSHTEPNGLLLHYQRRHPEHYVDYTYMATKLWAGP-DPSPPSL 1360
+ C+ C ++ E GL+ HY +H E T A G D P L
Sbjct: 1370 DEHRRQQHFSHRCQLCDFAARERVGLVKHYLEQHEE-----TSAAVAASDGDGDAGQPPL 1424
Query: 1361 TMP-------------------AEAKTYRCRDCVFEAVSIWDITNHYQAFHPWAMNGDES 1401
P + Y+C DC + + IT H +
Sbjct: 1425 HCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRI----------- 1473
Query: 1402 VLLDIIKEKDAVEKPI---LSSEELAGPVNCENSIPTPFPEQEAECPEDARLSPEKSLQL 1458
EKP L A P + + E++ CPE +
Sbjct: 1474 ---------HTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLK 1524
Query: 1459 ASANPAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPGMKVKAADFAQDIDINPGAVYKCR 1518
PYQC C+ N L H +H + C
Sbjct: 1525 YHMTKHTGLKPYQCPECEYCTNRADALRVHQETRH----------------REARAFMCE 1568
Query: 1519 HC-PYINTRIHGVLTHYQKRHPSIKVTAEDFVHDV-EQSADISQNDVEETSRIFKQGYGA 1576
C TR +L + ++H K + H +A + + + T R
Sbjct: 1569 QCGKAFKTRF--LLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDR------HP 1620
Query: 1577 YRCKLCPYTHGTLEKLKIHYEKYH 1600
+ C+LC Y ++ H ++H
Sbjct: 1621 FFCRLCNYKAKQKFQVVKHVRRHH 1644
Score = 43.5 bits (101), Expect = 0.003
Identities = 113/541 (20%), Positives = 163/541 (30%), Gaps = 167/541 (30%)
Query: 1460 SANPAISSTPY-QCTVCQSEYNNLHGLLTHYGKKHPGMKVKAADFAQDIDINPGAVYKCR 1518
+A PA P+ QC C + H KH G+K ++C
Sbjct: 1160 TAAPARGPRPHLQCGDCGFTCKQSRCMQQHRRLKHEGVKP----------------HQCP 1203
Query: 1519 HCPYINTRIHGVLTHYQKRHPSI-----KVTAEDF------------VHDVEQS-----A 1556
C + TR + + H Q RH I + F VHD +
Sbjct: 1204 FCDFSTTRRYRLEAH-QSRHTGIGRIPCSSCPQTFGTNSKLRLHRLRVHDKTPTHFCPLC 1262
Query: 1557 DIS---QNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFDVFSQSPP 1613
D S ++D+ QG A+ C C + LK H + H PE P
Sbjct: 1263 DYSGYLRHDITRHVNSCHQGTPAFACSQCEAQFSSETALKQHALRRH--PE--------P 1312
Query: 1614 KLPVPLEPEMTTE----------VSPSQVSITEEEVGEEP-----------VSTSHFSTS 1652
P P P TTE + PS S+ + P S
Sbjct: 1313 AQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQHPRLECGACQEAFPSRLALDEH 1372
Query: 1653 HLVSHTVFRCQLCKYFCSTRKGIARHYRIKHNNVRA------------QP---------- 1690
H RCQLC + R G+ +HY +H A QP
Sbjct: 1373 RRQQHFSHRCQLCDFAARERVGLVKHYLEQHEETSAAVAASDGDGDAGQPPLHCPFCDFT 1432
Query: 1691 -------------EGKNNLFKCALCAYTNPIRKGLAAHYQKRHDIDAYYTHCLAASRTIS 1737
G L+KC CAY+ R+ + H + Y+ H
Sbjct: 1433 CRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWHSRIHTGEKPYHCH--------- 1483
Query: 1738 DKPNKVIIPSPPKDDSPQLSEELRRAVEKKKCSLCSFQSFSKKGI--VSHYMKRHPGVFP 1795
+ P D S +L +R E++K LC + K + + ++M +H G+ P
Sbjct: 1484 ------LCPYACADPS-RLKYHMRIHKEERK-YLCPECGYKCKWVNQLKYHMTKHTGLKP 1535
Query: 1796 KKQHASKLGGYFTAVYADEHEKPTLMEEEERGNFEKAEVEGEAQEIEWLPFRCIKCFKLS 1855
+ E E T + V E + E F C +C K +
Sbjct: 1536 YQ--------------CPECEYCT-------NRADALRVHQETRHREARAFMCEQCGK-A 1573
Query: 1856 FSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHN 1915
F T LL H H + Y C C + A L H H
Sbjct: 1574 FKTRFLLRTHLRKHS-----------------EAKPYVCNVCHRAFRWAAGLRHHALTHT 1616
Query: 1916 E 1916
+
Sbjct: 1617 D 1617
Score = 39.7 bits (91), Expect = 0.038
Identities = 79/427 (18%), Positives = 142/427 (33%), Gaps = 78/427 (18%)
Query: 838 DSGRLYYCKHCDFNNKSARSVSTHYQRMHPYIKFSFRYILDPNDHSAVYRCLECYIDYTN 897
D ++C CD++ ++ H H + + C +C +++
Sbjct: 1252 DKTPTHFCPLCDYSGYLRHDITRHVNSCH--------------QGTPAFACSQCEAQFSS 1297
Query: 898 FEDLQQHYGEHHPEAMNVLNFDHSDLI---YRCRFCSYTSPNVRSLMPHYQRMHPTVKIN 954
L+QH HPE ++ C C P+ SL H ++ HP ++
Sbjct: 1298 ETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPASLRGHTRKQHPRLECG 1357
Query: 955 NAM-IFSSYVV----EQQEGLNTESQ----TLRE----ILNSAPKNMATSTPVARGGGLP 1001
F S + +Q+ + Q RE + + ++ TS VA G
Sbjct: 1358 ACQEAFPSRLALDEHRRQQHFSHRCQLCDFAARERVGLVKHYLEQHEETSAAVAASDG-- 1415
Query: 1002 ATFNKNTPKTFTPECE-NQKDPLV--------NTVVVYDCDVCSFASPNMHSVLVHYQKK 1052
+ P P C+ + LV +Y C C++++ N + H +
Sbjct: 1416 -DGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGGTRLYKCTDCAYSTKNRQKITWH-SRI 1473
Query: 1053 HPEEK-----------ASYFRIQKTMRMVSVDRGSALSQLSFE---VGAPMSPKMSNMGS 1098
H EK A R++ MR+ +R + ++ V + G
Sbjct: 1474 HTGEKPYHCHLCPYACADPSRLKYHMRIHKEERKYLCPECGYKCKWVNQLKYHMTKHTGL 1533
Query: 1099 PPPPQPPPPDLSTELYYCKHCSYSNRSVVGVLVHYQKRHPEIKV-TAKYIRQAPPTAAMM 1157
P Y C C Y + VH + RH E + + +A T ++
Sbjct: 1534 KP-------------YQCPECEYCTNRADALRVHQETRHREARAFMCEQCGKAFKTRFLL 1580
Query: 1158 RGVEGPQGSPRPPAPIQQLNRSSSERDG------PPVENEMFFCQHCDYGNRTVKGVLIH 1211
R + S P +R+ G + FFC+ C+Y + V+ H
Sbjct: 1581 R-THLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKH 1639
Query: 1212 YQKKHRD 1218
++ H D
Sbjct: 1640 VRRHHPD 1646
Score = 39.7 bits (91), Expect = 0.038
Identities = 29/117 (24%), Positives = 50/117 (42%), Gaps = 10/117 (8%)
Query: 108 FQCKFCVRYFRSKNLLIEHTRKVHGAQAEGSSSGPPV---PGSLNYNIMMHEGFGKVFSC 164
F C+ C + F+++ LL H RK A+ + L ++ + H F C
Sbjct: 1565 FMCEQCGKAFKTRFLLRTHLRKHSEAKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFF-C 1623
Query: 165 QFCTYKSPRRARIIKHQKMYHKNNLKETTAPPPAPAPMPDPVVPPVSLQDPCKELPA 221
+ C YK+ ++ +++KH + +H + P DP P V L D E P+
Sbjct: 1624 RLCNYKAKQKFQVVKHVRRHHPDQ------ADPNQGVGKDPTTPTVHLHDVQLEDPS 1674
Score = 38.5 bits (88), Expect = 0.084
Identities = 18/55 (32%), Positives = 26/55 (47%), Gaps = 2/55 (3%)
Query: 440 QCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
+C FCPF T + + H+ +H K +++C EC F L H HTG
Sbjct: 373 RCTFCPFATFNPVAYQDHVGKMHAHEK--IHQCPECNFATAHKRVLIRHMLLHTG 425
Score = 37.7 bits (86), Expect = 0.14
Identities = 64/308 (20%), Positives = 103/308 (33%), Gaps = 88/308 (28%)
Query: 843 YYCKHCDFNNKSARSVSTHYQRMHPYIKFSFRYILDPNDHSAVYRCLECYIDYTNFEDLQ 902
++C HCDF + H ++ HP S RC C N Q
Sbjct: 343 FHCPHCDFACSNKHLFRKHKKQGHP--------------GSEELRCTFCPFATFNPVAYQ 388
Query: 903 QHYGEHHPEAMNVLNFDHSDLIYRCRFCSYTSPNVRSLMPHYQRMHPTVKINNAMIFSSY 962
H G+ H + I++C C++ + + R L+ H +H K + +
Sbjct: 389 DHVGKMHAH----------EKIHQCPECNFATAHKRVLIRH-MLLHTGEKPHKCELCDF- 436
Query: 963 VVEQQEGLNTESQTLREILNSAPKNMATSTPVARGGGLPATFNKNTPKTFTPECENQKDP 1022
T R++ + K+M T + N KD
Sbjct: 437 -------------TCRDV-SYLSKHMLTHS-------------------------NTKD- 456
Query: 1023 LVNTVVVYDCDVCSFASPNMHSVLVHYQK-----KHPEEKASYFRIQKTMRMVSVDRGSA 1077
Y C C + + H + VH +K ++ + SY R + ++ S
Sbjct: 457 -------YMCTECGYVTKWKHYLRVHMRKHAGDLRYQCNQCSY-RCHRADQLSSHKLRHQ 508
Query: 1078 LSQLSFEVGAPMSPK----MSNMGSPPPPQPPPPDLSTELYYCKHCSYSNRSVVGVLVHY 1133
L EV A + +M S P P P LY C +CSY +R VL H
Sbjct: 509 GKSLMCEVCAFACKRKYELQKHMASQHHPGTPAP-----LYPCHYCSYQSRHKQAVLSHE 563
Query: 1134 QKRHPEIK 1141
+H ++
Sbjct: 564 NCKHTRLR 571
Score = 37.0 bits (84), Expect = 0.24
Identities = 105/560 (18%), Positives = 172/560 (30%), Gaps = 113/560 (20%)
Query: 845 CKHCDFNNKSARSVSTHYQRMH--------PYIKFSF--RYILDPND--HSAVYR--CLE 890
C C F K +R + H + H P+ FS RY L+ + H+ + R C
Sbjct: 1173 CGDCGFTCKQSRCMQQHRRLKHEGVKPHQCPFCDFSTTRRYRLEAHQSRHTGIGRIPCSS 1232
Query: 891 CYIDYTNFEDLQQHYGEHHPEAMNVLNFDHSDLIYRCRFCSYTSPNVRSLMPHYQRMH-- 948
C Q +G + ++ L + C C Y+ + H H
Sbjct: 1233 C----------PQTFGTNSKLRLHRLRVHDKTPTHFCPLCDYSGYLRHDITRHVNSCHQG 1282
Query: 949 -PTVKINNAMI-FSSYVVEQQEGLNTESQTLREILNSAPKNMATSTPVARGGGL---PAT 1003
P + FSS +Q L + + S + +R G L PA+
Sbjct: 1283 TPAFACSQCEAQFSSETALKQHALRRHPEPAQPAPGSPAETTEGPLHCSRCGLLCPSPAS 1342
Query: 1004 FNKNTPKTFTP-ECENQKDPLVNTVVV----------YDCDVCSFASPNMHSVLVHYQKK 1052
+T K EC ++ + + + + C +C FA+ ++ HY ++
Sbjct: 1343 LRGHTRKQHPRLECGACQEAFPSRLALDEHRRQQHFSHRCQLCDFAARERVGLVKHYLEQ 1402
Query: 1053 HPEEKASYFRIQKTMRMVSVDRGSALSQLSFEVGAPMSPKMSNMGSPPPPQPPPPDLSTE 1112
H E A+ + + + G T
Sbjct: 1403 HEETSAAVAASDGDGDAGQPPLHCPFCDFTCRHQLVLDHHVKGHGG------------TR 1450
Query: 1113 LYYCKHCSYSNRSVVGVLVHYQKRHPEIKVTAKYIRQAPPTAAMMRGVEGPQGSPRPPAP 1172
LY C C+YS ++ + H + E Y P A P+
Sbjct: 1451 LYKCTDCAYSTKNRQKITWHSRIHTGE----KPYHCHLCPYACA------------DPSR 1494
Query: 1173 IQQLNRSSSERDGPPVENEMFFCQHCDYGNRTVKGVLIHYQKKHRDFKANADVIRQHTAT 1232
++ R E + C C Y + V + H K HT
Sbjct: 1495 LKYHMRIHKEE-------RKYLCPECGYKCKWVNQLKYHMTK--------------HTGL 1533
Query: 1233 IRSLCDRNQ--KKPASCVLVSPSNLERDKTKLRALKCRQCSYTSPYFYALRKHIKKDHPA 1290
C + A + V R+ RA C QC + LR H++K H
Sbjct: 1534 KPYQCPECEYCTNRADALRVHQETRHREA---RAFMCEQCGKAFKTRFLLRTHLRK-HSE 1589
Query: 1291 LKATVTSI----MRWAF------LDGLIEAGYHCEWCIYSHTEPNGLLLHYQRRHPEHYV 1340
K V ++ RWA L + C C Y + ++ H +R HP+
Sbjct: 1590 AKPYVCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRHHPDQ-- 1647
Query: 1341 DYTYMATKLWAGPDPSPPSL 1360
G DP+ P++
Sbjct: 1648 ----ADPNQGVGKDPTTPTV 1663
Score = 35.4 bits (80), Expect = 0.71
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 2/54 (3%)
Query: 438 RFQCPFCPFLTMHRRSISRH-IENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQ 490
RF CP CPF R++ H I L ++ C CPFT ++ L H++
Sbjct: 1103 RFSCPTCPFSCQQERALRTHQIRGCPLE-ESGELHCSLCPFTAPAATALRLHQK 1155
Score = 35.0 bits (79), Expect = 0.93
Identities = 25/137 (18%), Positives = 50/137 (36%), Gaps = 1/137 (0%)
Query: 441 CPFCPFLTMHRRSISRHIENIHLSGKTA-VYKCDECPFTCKSSLKLGAHKQCHTGTTSDW 499
C C F + + +H+ + H G A +Y C C + + + +H+ C ++
Sbjct: 514 CEVCAFACKRKYELQKHMASQHHPGTPAPLYPCHYCSYQSRHKQAVLSHENCKHTRLREF 573
Query: 500 DAVNSQSESISSSLNEGVVSYESSSINGRKSGVMLDPLQQQQPPQPPPPPPPPPPSQPQP 559
+ S++ + G ++ + Q+ + P PPP Q
Sbjct: 574 HCALCDYRTFSNTTLLFHKRKAHGYVPGDQAWQLRYASQEPEGAMQGPTPPPDSEPSNQL 633
Query: 560 LQQPQPPQLQPPHQVPP 576
+P+ P +P V P
Sbjct: 634 SARPEGPGHEPGTVVDP 650
Score = 34.3 bits (77), Expect = 1.6
Identities = 28/144 (19%), Positives = 52/144 (36%), Gaps = 34/144 (23%)
Query: 1193 FFCQHCDYGNRTVKGVLIHYQKKHRDFKANADVIRQHTATIRSLCDRNQKKPASCVLVSP 1252
+ C C Y + HY + H +R+H +R C++ + C
Sbjct: 457 YMCTECGYVTKWK-----HYLRVH---------MRKHAGDLRYQCNQCSYR---CHRADQ 499
Query: 1253 SNLERDKTKLRALKCRQCSYTSPYFYALRKHI-KKDHPALKATVTSIMRWAFLDGLIEAG 1311
+ + + + ++L C C++ Y L+KH+ + HP A +
Sbjct: 500 LSSHKLRHQGKSLMCEVCAFACKRKYELQKHMASQHHPGTPAPL---------------- 543
Query: 1312 YHCEWCIYSHTEPNGLLLHYQRRH 1335
Y C +C Y +L H +H
Sbjct: 544 YPCHYCSYQSRHKQAVLSHENCKH 567
Score = 33.1 bits (74), Expect = 3.5
Identities = 27/136 (19%), Positives = 53/136 (38%), Gaps = 10/136 (7%)
Query: 360 TERSRYGMTDMTNSSADLETNSMLNDSSSDEELNEIDSENGLSAMDHQTSGLSAEQLMGS 419
T +++ ++ ++N + N SS D + + + G + T S +Q
Sbjct: 1061 TPQTQPDVSPLSNGDSAPPKNGSTESSSGDGDTVLVQKQKG-ARFSCPTCPFSCQQERAL 1119
Query: 420 DGNKLLETKGIPFRRFMNRFQCPFCPFLTMHRRSISRHIENIHLS-----GKTAVYKCDE 474
+++ +G P C CPF ++ H + H + G +C +
Sbjct: 1120 RTHQI---RGCPLEE-SGELHCSLCPFTAPAATALRLHQKRRHPTAAPARGPRPHLQCGD 1175
Query: 475 CPFTCKSSLKLGAHKQ 490
C FTCK S + H++
Sbjct: 1176 CGFTCKQSRCMQQHRR 1191
Score = 32.3 bits (72), Expect = 6.0
Identities = 28/152 (18%), Positives = 55/152 (36%), Gaps = 17/152 (11%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTGTTSD 498
+QCP C + T ++ H E H + + C++C K+ L H + H+
Sbjct: 1536 YQCPECEYCTNRADALRVHQETRHREAR--AFMCEQCGKAFKTRFLLRTHLRKHSEAKPY 1593
Query: 499 WDAVNSQSESISSSLNEGVVSYES--------SSINGRKSGVMLDPLQQQQPPQPPP--- 547
V ++ ++ L +++ + ++ ++ +++ P Q P
Sbjct: 1594 VCNVCHRAFRWAAGLRHHALTHTDRHPFFCRLCNYKAKQKFQVVKHVRRHHPDQADPNQG 1653
Query: 548 ----PPPPPPPSQPQPLQQPQPPQLQPPHQVP 575
P P L+ P PP PH P
Sbjct: 1654 VGKDPTTPTVHLHDVQLEDPSPPAPAAPHTGP 1685
Score = 32.0 bits (71), Expect = 7.9
Identities = 15/60 (25%), Positives = 28/60 (46%), Gaps = 3/60 (5%)
Query: 441 CPFCPFLTMHRRSISRHIENIH---LSGKTAVYKCDECPFTCKSSLKLGAHKQCHTGTTS 497
CP C + + R +++RH+ ++H + + Y C C + S L H + HT +
Sbjct: 221 CPLCHYSAVERNALNRHMASMHEDISNFYSDTYACPVCREEFRLSQALKEHLKSHTAAAA 280
>gi|239757212 PREDICTED: similar to hCG1773661 [Homo sapiens]
Length = 1119
Score = 122 bits (305), Expect = 6e-27
Identities = 236/1086 (21%), Positives = 386/1086 (35%), Gaps = 203/1086 (18%)
Query: 1468 TPYQCTVCQSEYNNLHGLLTHYGKKHPGMKVKAAD-----FAQDIDINPGAVYKCRHCPY 1522
TP++C C +N L H + H G K + F + N V PY
Sbjct: 129 TPFRCEECGKAFNQSSNLTDHK-RIHTGEKTYKCEECGKAFKGSSNFNAHKVIHTAEKPY 187
Query: 1523 INTRIHGVLTHYQ--KRHPSIKVTAEDFVHDVEQSADISQNDVEETSRIFKQGYGAYRCK 1580
H+ ++H I + + + E SQ+ I G Y+C+
Sbjct: 188 KCEDCGKTFNHFSALRKHKIIHTGKKPYKRE-ECGKAFSQSSTLRKHEIIHTGEKPYKCE 246
Query: 1581 LCPYTHGTLEKLKIHYEKYHNQPEFDVFSQSPPKLPVPLEPEMTTEVSPSQVSITEEEVG 1640
C KL +H + + + EE G
Sbjct: 247 ECGKAFKWSSKLTVHKVVHTGEKPYKC-----------------------------EECG 277
Query: 1641 EEPVSTSHFST--SHLVSHT---VFRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNN 1695
+ + S FST H + HT ++C+ C ++ + +H +I H +
Sbjct: 278 K---AFSQFSTLKKHKIIHTGKKPYKCEECGKAFNSSSTLMKH-KIIHTGEKP------- 326
Query: 1696 LFKCALCAYTNPIRKGLAAHYQKRHDIDAYYT--HCLAASRTISDKPNKVIIPSPPKDDS 1753
+KC C L H + H + Y C A SD II + K
Sbjct: 327 -YKCEECGKAFRQSSHLTRH-KAIHTGEKPYKCEECGKAFNHFSDLRRHKIIHTGKK--- 381
Query: 1754 PQLSEELRRAVEKK----------------KCSLCSFQSFSKKGIVSHYMKRHPGVFPKK 1797
P EE +A + KC C ++F ++ + H G P K
Sbjct: 382 PYKCEECGKAFSQSSTLRNHQIIHTGEKPYKCEECG-KAFKWSSKLTVHKVIHTGEKPCK 440
Query: 1798 -QHASKLGGYFTAVYADE--HEKPTLMEEEERGN-FEKAEVEGEAQEIEW--LPFRCIKC 1851
+ K +F+A+ + H + L + EE G F + + + + I P++C +C
Sbjct: 441 CEECGKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEEC 500
Query: 1852 FKLSFSTAELLCMHYTDH----------------HSRDLKRDFII-LGNGPRLQNSTYQC 1894
K +F + L H H H L+R II G P Y+C
Sbjct: 501 GK-AFRQSSHLTRHKAIHTGEKPYKCEECGKAFSHFSALRRHKIIHTGKKP------YKC 553
Query: 1895 KHCDSKLQSTAELTSHLNIHNEEFQKRAKRQERRKQL-----LSKQKYADGAFADFKQER 1949
+ C + L H IH E K K +E K L+ K A K E
Sbjct: 554 EECGKAFSHFSALRRHKIIHTGE--KPYKCEECGKAFKWSSKLTVHKVIHTAEKPCKCEE 611
Query: 1950 PFGHLEEVPKIKERKVVG-----YKCKFCVEVHPTLRAICNHLRKHVQYGNVP-AVSAAV 2003
+ +++ KV+ YKC+ CV+ + A+ H K + G P
Sbjct: 612 CGKSFKHFSALRKHKVIHTREKLYKCEECVKAFNSFSALMKH--KVIHTGEKPYKCEECG 669
Query: 2004 KGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRH--NLDRHMQTHHGHHKPFRCKLCSF 2061
K + + + + T E C+ C AF+H L +H H G KP++C+ C
Sbjct: 670 KAFKWSSKLTVHKVIHTGEKPCKCEECG--KAFKHFSALRKHKVIHTGK-KPYKCEECGK 726
Query: 2062 KSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVH-----------GKAL 2110
S +S L+ H + H+GE YKC C + +S+L H + +H GKA
Sbjct: 727 AFSQSSSLRKHEI-IHSGEKPYKCEECGKAFKWLSKLTVHKV-IHTAEKPCKCEECGKAF 784
Query: 2111 TLPRPRIVSLLSSHSH-HSSQKATPAEEVEDS-NDSS-YSEPPDVQQQLNHYQSAALARN 2167
+ S L H H+ +K EE + NDSS + + Y+ A +
Sbjct: 785 -----KHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKHKIIHTGKKPYKCAECGKA 839
Query: 2168 NSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSF 2227
+ S + A E+ + CE C ++++H + H +KL+KC++C
Sbjct: 840 FKQSSHLTRHKAIHTGEKPYK----CEECGKDFNNSSTLKKH-KLIHTREKLYKCEECVK 894
Query: 2228 YTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVC 2287
SA H + G K +C C K+ + +H V+H E+ E C
Sbjct: 895 AFNNFSALMKH------KIIHTGEKPYKCEECGKAFKWSSKLTEHKVIHTGEKPCKCEEC 948
Query: 2288 RSKLSKYLQGV-----------VFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYE 2336
K K+ + ++CD+C ++ +L +H H KPYKC+ C
Sbjct: 949 -DKAFKHFSALRKHKVIHTGKKPYQCDECGKAFNNSSTLTKHKIIHTGEKPYKCEECGKA 1007
Query: 2337 TKHTEELDSHLRDEHKVSRNFELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDR 2396
+ L H + H V + + + E+ + SS
Sbjct: 1008 FSQSSILTKH-KIIHSVEKPY---------KCEECGKAFNQSS----------------- 1040
Query: 2397 ELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRHGMAL-NDTKQVSREEIHPKE 2455
+ H EK + CE CG+AF Q S RH H + K+V + +P
Sbjct: 1041 ---HLTRHKTIHTGEKPYKCEECGKAFIQCSYLIRHKTIHTREKPTNVKKVPKLLSNPHT 1097
Query: 2456 IMENSV 2461
+++ ++
Sbjct: 1098 LLDKTI 1103
Score = 107 bits (266), Expect = 2e-22
Identities = 138/648 (21%), Positives = 231/648 (35%), Gaps = 116/648 (17%)
Query: 1829 FEKAEVEGEAQEIEWLPFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQ 1888
F K + + + F+CIKC K SF L H H ++
Sbjct: 30 FHKYSNRNKVRHTKKKTFKCIKCSK-SFFMLSCLIRHKRIH-----------------IR 71
Query: 1889 NSTYQCKHCDSKLQSTAELTSHLNIHNEEFQKRAKR---QERRKQLLSKQKYADGAFADF 1945
+ Y+C+ +S + LT H IH E+ + K+ + +K K F
Sbjct: 72 QNIYKCEERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGNAFKFSSTFTKHKRIHTGETPF 131
Query: 1946 KQERPFGHLEEVPKIKERKVVG-----YKCKFCVEVHP-----TLRAICNHLRKHVQYGN 1995
+ E + + + K + YKC+ C + + + K + +
Sbjct: 132 RCEECGKAFNQSSNLTDHKRIHTGEKTYKCEECGKAFKGSSNFNAHKVIHTAEKPYKCED 191
Query: 1996 VPAVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFR 2055
LR H+ H + RE+ C + L +H H G KP++
Sbjct: 192 CGKTFNHFSALRKHKIIHTGKKPYKREE------CGKAFSQSSTLRKHEIIHTGE-KPYK 244
Query: 2056 CKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSL------------ 2103
C+ C ++S+L H + H GE YKC C + S LK+H +
Sbjct: 245 CEECGKAFKWSSKLTVHKV-VHTGEKPYKCEECGKAFSQFSTLKKHKIIHTGKKPYKCEE 303
Query: 2104 --KVHGKALTLPRPRIVSLLSSHSHHSSQKATPAEEVEDSNDSSYSEPPDVQQQLNHYQS 2161
K + TL + +I+ H+ +K EE + QS
Sbjct: 304 CGKAFNSSSTLMKHKII--------HTGEKPYKCEECGKA----------------FRQS 339
Query: 2162 AALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFK 2221
+ L R+ A T +K CE C + + +RRH + H GKK +K
Sbjct: 340 SHLTRHK-----------AIHTGEKP---YKCEECGKAFNHFSDLRRH-KIIHTGKKPYK 384
Query: 2222 CKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERV 2281
C++C AF+ + + G K +C C K+ + H V+H E+
Sbjct: 385 CEECG------KAFSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKP 438
Query: 2282 VPIEVCRSKLSKYLQGV-----------VFRCDKCTFTCSSDESLQQHIEKHNELKPYKC 2330
E C K K+ + +++C++C ++ L +H H KPYKC
Sbjct: 439 CKCEEC-GKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKC 497
Query: 2331 QLCYYETKHTEELDSHLRDEHKVSRNF--ELVGRVNLDQLEQMKEKMESSSSDDEDKEEE 2388
+ C + + L H + H + + E G+ + K+ + EE
Sbjct: 498 EECGKAFRQSSHLTRH-KAIHTGEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEEC 556
Query: 2389 MNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRH 2436
+ + L R H EK + CE CG+AF S+ H + H
Sbjct: 557 GKAFSHFSALRR---HKIIHTGEKPYKCEECGKAFKWSSKLTVHKVIH 601
Score = 43.1 bits (100), Expect = 0.003
Identities = 67/290 (23%), Positives = 98/290 (33%), Gaps = 76/290 (26%)
Query: 1845 PFRCIKCFKLSFSTAELL-----------------CMHYTDHHSRDLKRDFIILGNGPRL 1887
P++C +C K F+ + L C+ ++ S +K I G P
Sbjct: 858 PYKCEECGK-DFNNSSTLKKHKLIHTREKLYKCEECVKAFNNFSALMKHKIIHTGEKP-- 914
Query: 1888 QNSTYQCKHCDSKLQSTAELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQ 1947
Y+C+ C + +++LT H IH E K K +E D AF F
Sbjct: 915 ----YKCEECGKAFKWSSKLTEHKVIHTGE--KPCKCEE-----------CDKAFKHFSA 957
Query: 1948 ERPFGHLEEVPKIKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVPAVSAAVKGLR 2007
R K+ Y+C C + + H K + G P G
Sbjct: 958 LRKH-------KVIHTGKKPYQCDECGKAFNNSSTLTKH--KIIHTGEKP-YKCEECGKA 1007
Query: 2008 SHERSHLAL--AMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCS---FK 2062
+ S L + + E Y C+ C +L RH H G KP++C+ C +
Sbjct: 1008 FSQSSILTKHKIIHSVEKPYKCEECGKAFNQSSHLTRHKTIHTGE-KPYKCEECGKAFIQ 1066
Query: 2063 SSYNSRLKT--------------------HIL---KAHAGEHAYKCSWCS 2089
SY R KT H L H GE YKC C+
Sbjct: 1067 CSYLIRHKTIHTREKPTNVKKVPKLLSNPHTLLDKTIHTGEKPYKCEECA 1116
Score = 34.7 bits (78), Expect = 1.2
Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 3/55 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHT 493
F+C C +++ H + IH KT YKC+EC K S AHK HT
Sbjct: 131 FRCEECGKAFNQSSNLTDH-KRIHTGEKT--YKCEECGKAFKGSSNFNAHKVIHT 182
Score = 34.7 bits (78), Expect = 1.2
Identities = 21/55 (38%), Positives = 27/55 (49%), Gaps = 3/55 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHT 493
++C C H ++ RH + IH K YKC+EC K S KL HK HT
Sbjct: 551 YKCEECGKAFSHFSALRRH-KIIHTGEKP--YKCEECGKAFKWSSKLTVHKVIHT 602
Score = 33.1 bits (74), Expect = 3.5
Identities = 20/42 (47%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 453 SISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
S R E IH K YKC+EC K S KL HK HTG
Sbjct: 228 STLRKHEIIHTGEKP--YKCEECGKAFKWSSKLTVHKVVHTG 267
Score = 33.1 bits (74), Expect = 3.5
Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C ++ H + IH K YKC+EC K S KL HK HTG
Sbjct: 383 YKCEECGKAFSQSSTLRNH-QIIHTGEKP--YKCEECGKAFKWSSKLTVHKVIHTG 435
Score = 32.3 bits (72), Expect = 6.0
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C + ++ +H + IH K YKC+EC K S KL HK HTG
Sbjct: 887 YKCEECVKAFNNFSALMKH-KIIHTGEKP--YKCEECGKAFKWSSKLTEHKVIHTG 939
Score = 32.0 bits (71), Expect = 7.9
Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C ++ +H + IH K YKC+EC K S KL HK HTG
Sbjct: 635 YKCEECVKAFNSFSALMKH-KVIHTGEKP--YKCEECGKAFKWSSKLTVHKVIHTG 687
>gi|239751718 PREDICTED: similar to hCG1773661 [Homo sapiens]
Length = 1119
Score = 122 bits (305), Expect = 6e-27
Identities = 236/1086 (21%), Positives = 386/1086 (35%), Gaps = 203/1086 (18%)
Query: 1468 TPYQCTVCQSEYNNLHGLLTHYGKKHPGMKVKAAD-----FAQDIDINPGAVYKCRHCPY 1522
TP++C C +N L H + H G K + F + N V PY
Sbjct: 129 TPFRCEECGKAFNQSSNLTDHK-RIHTGEKTYKCEECGKAFKGSSNFNAHKVIHTAEKPY 187
Query: 1523 INTRIHGVLTHYQ--KRHPSIKVTAEDFVHDVEQSADISQNDVEETSRIFKQGYGAYRCK 1580
H+ ++H I + + + E SQ+ I G Y+C+
Sbjct: 188 KCEDCGKTFNHFSALRKHKIIHTGKKPYKRE-ECGKAFSQSSTLRKHEIIHTGEKPYKCE 246
Query: 1581 LCPYTHGTLEKLKIHYEKYHNQPEFDVFSQSPPKLPVPLEPEMTTEVSPSQVSITEEEVG 1640
C KL +H + + + EE G
Sbjct: 247 ECGKAFKWSSKLTVHKVVHTGEKPYKC-----------------------------EECG 277
Query: 1641 EEPVSTSHFST--SHLVSHT---VFRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNN 1695
+ + S FST H + HT ++C+ C ++ + +H +I H +
Sbjct: 278 K---AFSQFSTLKKHKIIHTGKKPYKCEECGKAFNSSSTLMKH-KIIHTGEKP------- 326
Query: 1696 LFKCALCAYTNPIRKGLAAHYQKRHDIDAYYT--HCLAASRTISDKPNKVIIPSPPKDDS 1753
+KC C L H + H + Y C A SD II + K
Sbjct: 327 -YKCEECGKAFRQSSHLTRH-KAIHTGEKPYKCEECGKAFNHFSDLRRHKIIHTGKK--- 381
Query: 1754 PQLSEELRRAVEKK----------------KCSLCSFQSFSKKGIVSHYMKRHPGVFPKK 1797
P EE +A + KC C ++F ++ + H G P K
Sbjct: 382 PYKCEECGKAFSQSSTLRNHQIIHTGEKPYKCEECG-KAFKWSSKLTVHKVIHTGEKPCK 440
Query: 1798 -QHASKLGGYFTAVYADE--HEKPTLMEEEERGN-FEKAEVEGEAQEIEW--LPFRCIKC 1851
+ K +F+A+ + H + L + EE G F + + + + I P++C +C
Sbjct: 441 CEECGKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEEC 500
Query: 1852 FKLSFSTAELLCMHYTDH----------------HSRDLKRDFII-LGNGPRLQNSTYQC 1894
K +F + L H H H L+R II G P Y+C
Sbjct: 501 GK-AFRQSSHLTRHKAIHTGEKPYKCEECGKAFSHFSALRRHKIIHTGKKP------YKC 553
Query: 1895 KHCDSKLQSTAELTSHLNIHNEEFQKRAKRQERRKQL-----LSKQKYADGAFADFKQER 1949
+ C + L H IH E K K +E K L+ K A K E
Sbjct: 554 EECGKAFSHFSALRRHKIIHTGE--KPYKCEECGKAFKWSSKLTVHKVIHTAEKPCKCEE 611
Query: 1950 PFGHLEEVPKIKERKVVG-----YKCKFCVEVHPTLRAICNHLRKHVQYGNVP-AVSAAV 2003
+ +++ KV+ YKC+ CV+ + A+ H K + G P
Sbjct: 612 CGKSFKHFSALRKHKVIHTREKLYKCEECVKAFNSFSALMKH--KVIHTGEKPYKCEECG 669
Query: 2004 KGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRH--NLDRHMQTHHGHHKPFRCKLCSF 2061
K + + + + T E C+ C AF+H L +H H G KP++C+ C
Sbjct: 670 KAFKWSSKLTVHKVIHTGEKPCKCEECG--KAFKHFSALRKHKVIHTGK-KPYKCEECGK 726
Query: 2062 KSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVH-----------GKAL 2110
S +S L+ H + H+GE YKC C + +S+L H + +H GKA
Sbjct: 727 AFSQSSSLRKHEI-IHSGEKPYKCEECGKAFKWLSKLTVHKV-IHTAEKPCKCEECGKAF 784
Query: 2111 TLPRPRIVSLLSSHSH-HSSQKATPAEEVEDS-NDSS-YSEPPDVQQQLNHYQSAALARN 2167
+ S L H H+ +K EE + NDSS + + Y+ A +
Sbjct: 785 -----KHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKHKIIHTGKKPYKCAECGKA 839
Query: 2168 NSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSF 2227
+ S + A E+ + CE C ++++H + H +KL+KC++C
Sbjct: 840 FKQSSHLTRHKAIHTGEKPYK----CEECGKDFNNSSTLKKH-KLIHTREKLYKCEECVK 894
Query: 2228 YTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVC 2287
SA H + G K +C C K+ + +H V+H E+ E C
Sbjct: 895 AFNNFSALMKH------KIIHTGEKPYKCEECGKAFKWSSKLTEHKVIHTGEKPCKCEEC 948
Query: 2288 RSKLSKYLQGV-----------VFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYE 2336
K K+ + ++CD+C ++ +L +H H KPYKC+ C
Sbjct: 949 -DKAFKHFSALRKHKVIHTGKKPYQCDECGKAFNNSSTLTKHKIIHTGEKPYKCEECGKA 1007
Query: 2337 TKHTEELDSHLRDEHKVSRNFELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDR 2396
+ L H + H V + + + E+ + SS
Sbjct: 1008 FSQSSILTKH-KIIHSVEKPY---------KCEECGKAFNQSS----------------- 1040
Query: 2397 ELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRHGMAL-NDTKQVSREEIHPKE 2455
+ H EK + CE CG+AF Q S RH H + K+V + +P
Sbjct: 1041 ---HLTRHKTIHTGEKPYKCEECGKAFIQCSYLIRHKTIHTREKPTNVKKVPKLLSNPHT 1097
Query: 2456 IMENSV 2461
+++ ++
Sbjct: 1098 LLDKTI 1103
Score = 107 bits (266), Expect = 2e-22
Identities = 138/648 (21%), Positives = 231/648 (35%), Gaps = 116/648 (17%)
Query: 1829 FEKAEVEGEAQEIEWLPFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQ 1888
F K + + + F+CIKC K SF L H H ++
Sbjct: 30 FHKYSNRNKVRHTKKKTFKCIKCSK-SFFMLSCLIRHKRIH-----------------IR 71
Query: 1889 NSTYQCKHCDSKLQSTAELTSHLNIHNEEFQKRAKR---QERRKQLLSKQKYADGAFADF 1945
+ Y+C+ +S + LT H IH E+ + K+ + +K K F
Sbjct: 72 QNIYKCEERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGNAFKFSSTFTKHKRIHTGETPF 131
Query: 1946 KQERPFGHLEEVPKIKERKVVG-----YKCKFCVEVHP-----TLRAICNHLRKHVQYGN 1995
+ E + + + K + YKC+ C + + + K + +
Sbjct: 132 RCEECGKAFNQSSNLTDHKRIHTGEKTYKCEECGKAFKGSSNFNAHKVIHTAEKPYKCED 191
Query: 1996 VPAVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFR 2055
LR H+ H + RE+ C + L +H H G KP++
Sbjct: 192 CGKTFNHFSALRKHKIIHTGKKPYKREE------CGKAFSQSSTLRKHEIIHTGE-KPYK 244
Query: 2056 CKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSL------------ 2103
C+ C ++S+L H + H GE YKC C + S LK+H +
Sbjct: 245 CEECGKAFKWSSKLTVHKV-VHTGEKPYKCEECGKAFSQFSTLKKHKIIHTGKKPYKCEE 303
Query: 2104 --KVHGKALTLPRPRIVSLLSSHSHHSSQKATPAEEVEDSNDSSYSEPPDVQQQLNHYQS 2161
K + TL + +I+ H+ +K EE + QS
Sbjct: 304 CGKAFNSSSTLMKHKII--------HTGEKPYKCEECGKA----------------FRQS 339
Query: 2162 AALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFK 2221
+ L R+ A T +K CE C + + +RRH + H GKK +K
Sbjct: 340 SHLTRHK-----------AIHTGEKP---YKCEECGKAFNHFSDLRRH-KIIHTGKKPYK 384
Query: 2222 CKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERV 2281
C++C AF+ + + G K +C C K+ + H V+H E+
Sbjct: 385 CEECG------KAFSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKP 438
Query: 2282 VPIEVCRSKLSKYLQGV-----------VFRCDKCTFTCSSDESLQQHIEKHNELKPYKC 2330
E C K K+ + +++C++C ++ L +H H KPYKC
Sbjct: 439 CKCEEC-GKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKC 497
Query: 2331 QLCYYETKHTEELDSHLRDEHKVSRNF--ELVGRVNLDQLEQMKEKMESSSSDDEDKEEE 2388
+ C + + L H + H + + E G+ + K+ + EE
Sbjct: 498 EECGKAFRQSSHLTRH-KAIHTGEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEEC 556
Query: 2389 MNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRH 2436
+ + L R H EK + CE CG+AF S+ H + H
Sbjct: 557 GKAFSHFSALRR---HKIIHTGEKPYKCEECGKAFKWSSKLTVHKVIH 601
Score = 43.1 bits (100), Expect = 0.003
Identities = 67/290 (23%), Positives = 98/290 (33%), Gaps = 76/290 (26%)
Query: 1845 PFRCIKCFKLSFSTAELL-----------------CMHYTDHHSRDLKRDFIILGNGPRL 1887
P++C +C K F+ + L C+ ++ S +K I G P
Sbjct: 858 PYKCEECGK-DFNNSSTLKKHKLIHTREKLYKCEECVKAFNNFSALMKHKIIHTGEKP-- 914
Query: 1888 QNSTYQCKHCDSKLQSTAELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQ 1947
Y+C+ C + +++LT H IH E K K +E D AF F
Sbjct: 915 ----YKCEECGKAFKWSSKLTEHKVIHTGE--KPCKCEE-----------CDKAFKHFSA 957
Query: 1948 ERPFGHLEEVPKIKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVPAVSAAVKGLR 2007
R K+ Y+C C + + H K + G P G
Sbjct: 958 LRKH-------KVIHTGKKPYQCDECGKAFNNSSTLTKH--KIIHTGEKP-YKCEECGKA 1007
Query: 2008 SHERSHLAL--AMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCS---FK 2062
+ S L + + E Y C+ C +L RH H G KP++C+ C +
Sbjct: 1008 FSQSSILTKHKIIHSVEKPYKCEECGKAFNQSSHLTRHKTIHTGE-KPYKCEECGKAFIQ 1066
Query: 2063 SSYNSRLKT--------------------HIL---KAHAGEHAYKCSWCS 2089
SY R KT H L H GE YKC C+
Sbjct: 1067 CSYLIRHKTIHTREKPTNVKKVPKLLSNPHTLLDKTIHTGEKPYKCEECA 1116
Score = 34.7 bits (78), Expect = 1.2
Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 3/55 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHT 493
F+C C +++ H + IH KT YKC+EC K S AHK HT
Sbjct: 131 FRCEECGKAFNQSSNLTDH-KRIHTGEKT--YKCEECGKAFKGSSNFNAHKVIHT 182
Score = 34.7 bits (78), Expect = 1.2
Identities = 21/55 (38%), Positives = 27/55 (49%), Gaps = 3/55 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHT 493
++C C H ++ RH + IH K YKC+EC K S KL HK HT
Sbjct: 551 YKCEECGKAFSHFSALRRH-KIIHTGEKP--YKCEECGKAFKWSSKLTVHKVIHT 602
Score = 33.1 bits (74), Expect = 3.5
Identities = 20/42 (47%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 453 SISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
S R E IH K YKC+EC K S KL HK HTG
Sbjct: 228 STLRKHEIIHTGEKP--YKCEECGKAFKWSSKLTVHKVVHTG 267
Score = 33.1 bits (74), Expect = 3.5
Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C ++ H + IH K YKC+EC K S KL HK HTG
Sbjct: 383 YKCEECGKAFSQSSTLRNH-QIIHTGEKP--YKCEECGKAFKWSSKLTVHKVIHTG 435
Score = 32.3 bits (72), Expect = 6.0
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C + ++ +H + IH K YKC+EC K S KL HK HTG
Sbjct: 887 YKCEECVKAFNNFSALMKH-KIIHTGEKP--YKCEECGKAFKWSSKLTEHKVIHTG 939
Score = 32.0 bits (71), Expect = 7.9
Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C ++ +H + IH K YKC+EC K S KL HK HTG
Sbjct: 635 YKCEECVKAFNSFSALMKH-KVIHTGEKP--YKCEECGKAFKWSSKLTVHKVIHTG 687
>gi|239746221 PREDICTED: hypothetical protein XP_002343677 [Homo
sapiens]
Length = 1119
Score = 122 bits (305), Expect = 6e-27
Identities = 236/1086 (21%), Positives = 386/1086 (35%), Gaps = 203/1086 (18%)
Query: 1468 TPYQCTVCQSEYNNLHGLLTHYGKKHPGMKVKAAD-----FAQDIDINPGAVYKCRHCPY 1522
TP++C C +N L H + H G K + F + N V PY
Sbjct: 129 TPFRCEECGKAFNQSSNLTDHK-RIHTGEKTYKCEECGKAFKGSSNFNAHKVIHTAEKPY 187
Query: 1523 INTRIHGVLTHYQ--KRHPSIKVTAEDFVHDVEQSADISQNDVEETSRIFKQGYGAYRCK 1580
H+ ++H I + + + E SQ+ I G Y+C+
Sbjct: 188 KCEDCGKTFNHFSALRKHKIIHTGKKPYKRE-ECGKAFSQSSTLRKHEIIHTGEKPYKCE 246
Query: 1581 LCPYTHGTLEKLKIHYEKYHNQPEFDVFSQSPPKLPVPLEPEMTTEVSPSQVSITEEEVG 1640
C KL +H + + + EE G
Sbjct: 247 ECGKAFKWSSKLTVHKVVHTGEKPYKC-----------------------------EECG 277
Query: 1641 EEPVSTSHFST--SHLVSHT---VFRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNN 1695
+ + S FST H + HT ++C+ C ++ + +H +I H +
Sbjct: 278 K---AFSQFSTLKKHKIIHTGKKPYKCEECGKAFNSSSTLMKH-KIIHTGEKP------- 326
Query: 1696 LFKCALCAYTNPIRKGLAAHYQKRHDIDAYYT--HCLAASRTISDKPNKVIIPSPPKDDS 1753
+KC C L H + H + Y C A SD II + K
Sbjct: 327 -YKCEECGKAFRQSSHLTRH-KAIHTGEKPYKCEECGKAFNHFSDLRRHKIIHTGKK--- 381
Query: 1754 PQLSEELRRAVEKK----------------KCSLCSFQSFSKKGIVSHYMKRHPGVFPKK 1797
P EE +A + KC C ++F ++ + H G P K
Sbjct: 382 PYKCEECGKAFSQSSTLRNHQIIHTGEKPYKCEECG-KAFKWSSKLTVHKVIHTGEKPCK 440
Query: 1798 -QHASKLGGYFTAVYADE--HEKPTLMEEEERGN-FEKAEVEGEAQEIEW--LPFRCIKC 1851
+ K +F+A+ + H + L + EE G F + + + + I P++C +C
Sbjct: 441 CEECGKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEEC 500
Query: 1852 FKLSFSTAELLCMHYTDH----------------HSRDLKRDFII-LGNGPRLQNSTYQC 1894
K +F + L H H H L+R II G P Y+C
Sbjct: 501 GK-AFRQSSHLTRHKAIHTGEKPYKCEECGKAFSHFSALRRHKIIHTGKKP------YKC 553
Query: 1895 KHCDSKLQSTAELTSHLNIHNEEFQKRAKRQERRKQL-----LSKQKYADGAFADFKQER 1949
+ C + L H IH E K K +E K L+ K A K E
Sbjct: 554 EECGKAFSHFSALRRHKIIHTGE--KPYKCEECGKAFKWSSKLTVHKVIHTAEKPCKCEE 611
Query: 1950 PFGHLEEVPKIKERKVVG-----YKCKFCVEVHPTLRAICNHLRKHVQYGNVP-AVSAAV 2003
+ +++ KV+ YKC+ CV+ + A+ H K + G P
Sbjct: 612 CGKSFKHFSALRKHKVIHTREKLYKCEECVKAFNSFSALMKH--KVIHTGEKPYKCEECG 669
Query: 2004 KGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRH--NLDRHMQTHHGHHKPFRCKLCSF 2061
K + + + + T E C+ C AF+H L +H H G KP++C+ C
Sbjct: 670 KAFKWSSKLTVHKVIHTGEKPCKCEECG--KAFKHFSALRKHKVIHTGK-KPYKCEECGK 726
Query: 2062 KSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVH-----------GKAL 2110
S +S L+ H + H+GE YKC C + +S+L H + +H GKA
Sbjct: 727 AFSQSSSLRKHEI-IHSGEKPYKCEECGKAFKWLSKLTVHKV-IHTAEKPCKCEECGKAF 784
Query: 2111 TLPRPRIVSLLSSHSH-HSSQKATPAEEVEDS-NDSS-YSEPPDVQQQLNHYQSAALARN 2167
+ S L H H+ +K EE + NDSS + + Y+ A +
Sbjct: 785 -----KHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKHKIIHTGKKPYKCAECGKA 839
Query: 2168 NSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSF 2227
+ S + A E+ + CE C ++++H + H +KL+KC++C
Sbjct: 840 FKQSSHLTRHKAIHTGEKPYK----CEECGKDFNNSSTLKKH-KLIHTREKLYKCEECVK 894
Query: 2228 YTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVC 2287
SA H + G K +C C K+ + +H V+H E+ E C
Sbjct: 895 AFNNFSALMKH------KIIHTGEKPYKCEECGKAFKWSSKLTEHKVIHTGEKPCKCEEC 948
Query: 2288 RSKLSKYLQGV-----------VFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYE 2336
K K+ + ++CD+C ++ +L +H H KPYKC+ C
Sbjct: 949 -DKAFKHFSALRKHKVIHTGKKPYQCDECGKAFNNSSTLTKHKIIHTGEKPYKCEECGKA 1007
Query: 2337 TKHTEELDSHLRDEHKVSRNFELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDR 2396
+ L H + H V + + + E+ + SS
Sbjct: 1008 FSQSSILTKH-KIIHSVEKPY---------KCEECGKAFNQSS----------------- 1040
Query: 2397 ELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRHGMAL-NDTKQVSREEIHPKE 2455
+ H EK + CE CG+AF Q S RH H + K+V + +P
Sbjct: 1041 ---HLTRHKTIHTGEKPYKCEECGKAFIQCSYLIRHKTIHTREKPTNVKKVPKLLSNPHT 1097
Query: 2456 IMENSV 2461
+++ ++
Sbjct: 1098 LLDKTI 1103
Score = 107 bits (266), Expect = 2e-22
Identities = 138/648 (21%), Positives = 231/648 (35%), Gaps = 116/648 (17%)
Query: 1829 FEKAEVEGEAQEIEWLPFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQ 1888
F K + + + F+CIKC K SF L H H ++
Sbjct: 30 FHKYSNRNKVRHTKKKTFKCIKCSK-SFFMLSCLIRHKRIH-----------------IR 71
Query: 1889 NSTYQCKHCDSKLQSTAELTSHLNIHNEEFQKRAKR---QERRKQLLSKQKYADGAFADF 1945
+ Y+C+ +S + LT H IH E+ + K+ + +K K F
Sbjct: 72 QNIYKCEERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGNAFKFSSTFTKHKRIHTGETPF 131
Query: 1946 KQERPFGHLEEVPKIKERKVVG-----YKCKFCVEVHP-----TLRAICNHLRKHVQYGN 1995
+ E + + + K + YKC+ C + + + K + +
Sbjct: 132 RCEECGKAFNQSSNLTDHKRIHTGEKTYKCEECGKAFKGSSNFNAHKVIHTAEKPYKCED 191
Query: 1996 VPAVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFR 2055
LR H+ H + RE+ C + L +H H G KP++
Sbjct: 192 CGKTFNHFSALRKHKIIHTGKKPYKREE------CGKAFSQSSTLRKHEIIHTGE-KPYK 244
Query: 2056 CKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSL------------ 2103
C+ C ++S+L H + H GE YKC C + S LK+H +
Sbjct: 245 CEECGKAFKWSSKLTVHKV-VHTGEKPYKCEECGKAFSQFSTLKKHKIIHTGKKPYKCEE 303
Query: 2104 --KVHGKALTLPRPRIVSLLSSHSHHSSQKATPAEEVEDSNDSSYSEPPDVQQQLNHYQS 2161
K + TL + +I+ H+ +K EE + QS
Sbjct: 304 CGKAFNSSSTLMKHKII--------HTGEKPYKCEECGKA----------------FRQS 339
Query: 2162 AALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFK 2221
+ L R+ A T +K CE C + + +RRH + H GKK +K
Sbjct: 340 SHLTRHK-----------AIHTGEKP---YKCEECGKAFNHFSDLRRH-KIIHTGKKPYK 384
Query: 2222 CKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERV 2281
C++C AF+ + + G K +C C K+ + H V+H E+
Sbjct: 385 CEECG------KAFSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKP 438
Query: 2282 VPIEVCRSKLSKYLQGV-----------VFRCDKCTFTCSSDESLQQHIEKHNELKPYKC 2330
E C K K+ + +++C++C ++ L +H H KPYKC
Sbjct: 439 CKCEEC-GKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKC 497
Query: 2331 QLCYYETKHTEELDSHLRDEHKVSRNF--ELVGRVNLDQLEQMKEKMESSSSDDEDKEEE 2388
+ C + + L H + H + + E G+ + K+ + EE
Sbjct: 498 EECGKAFRQSSHLTRH-KAIHTGEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEEC 556
Query: 2389 MNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRH 2436
+ + L R H EK + CE CG+AF S+ H + H
Sbjct: 557 GKAFSHFSALRR---HKIIHTGEKPYKCEECGKAFKWSSKLTVHKVIH 601
Score = 43.1 bits (100), Expect = 0.003
Identities = 67/290 (23%), Positives = 98/290 (33%), Gaps = 76/290 (26%)
Query: 1845 PFRCIKCFKLSFSTAELL-----------------CMHYTDHHSRDLKRDFIILGNGPRL 1887
P++C +C K F+ + L C+ ++ S +K I G P
Sbjct: 858 PYKCEECGK-DFNNSSTLKKHKLIHTREKLYKCEECVKAFNNFSALMKHKIIHTGEKP-- 914
Query: 1888 QNSTYQCKHCDSKLQSTAELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQ 1947
Y+C+ C + +++LT H IH E K K +E D AF F
Sbjct: 915 ----YKCEECGKAFKWSSKLTEHKVIHTGE--KPCKCEE-----------CDKAFKHFSA 957
Query: 1948 ERPFGHLEEVPKIKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVPAVSAAVKGLR 2007
R K+ Y+C C + + H K + G P G
Sbjct: 958 LRKH-------KVIHTGKKPYQCDECGKAFNNSSTLTKH--KIIHTGEKP-YKCEECGKA 1007
Query: 2008 SHERSHLAL--AMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCS---FK 2062
+ S L + + E Y C+ C +L RH H G KP++C+ C +
Sbjct: 1008 FSQSSILTKHKIIHSVEKPYKCEECGKAFNQSSHLTRHKTIHTGE-KPYKCEECGKAFIQ 1066
Query: 2063 SSYNSRLKT--------------------HIL---KAHAGEHAYKCSWCS 2089
SY R KT H L H GE YKC C+
Sbjct: 1067 CSYLIRHKTIHTREKPTNVKKVPKLLSNPHTLLDKTIHTGEKPYKCEECA 1116
Score = 34.7 bits (78), Expect = 1.2
Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 3/55 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHT 493
F+C C +++ H + IH KT YKC+EC K S AHK HT
Sbjct: 131 FRCEECGKAFNQSSNLTDH-KRIHTGEKT--YKCEECGKAFKGSSNFNAHKVIHT 182
Score = 34.7 bits (78), Expect = 1.2
Identities = 21/55 (38%), Positives = 27/55 (49%), Gaps = 3/55 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHT 493
++C C H ++ RH + IH K YKC+EC K S KL HK HT
Sbjct: 551 YKCEECGKAFSHFSALRRH-KIIHTGEKP--YKCEECGKAFKWSSKLTVHKVIHT 602
Score = 33.1 bits (74), Expect = 3.5
Identities = 20/42 (47%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 453 SISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
S R E IH K YKC+EC K S KL HK HTG
Sbjct: 228 STLRKHEIIHTGEKP--YKCEECGKAFKWSSKLTVHKVVHTG 267
Score = 33.1 bits (74), Expect = 3.5
Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C ++ H + IH K YKC+EC K S KL HK HTG
Sbjct: 383 YKCEECGKAFSQSSTLRNH-QIIHTGEKP--YKCEECGKAFKWSSKLTVHKVIHTG 435
Score = 32.3 bits (72), Expect = 6.0
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C + ++ +H + IH K YKC+EC K S KL HK HTG
Sbjct: 887 YKCEECVKAFNNFSALMKH-KIIHTGEKP--YKCEECGKAFKWSSKLTEHKVIHTG 939
Score = 32.0 bits (71), Expect = 7.9
Identities = 20/56 (35%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C ++ +H + IH K YKC+EC K S KL HK HTG
Sbjct: 635 YKCEECVKAFNSFSALMKH-KVIHTGEKP--YKCEECGKAFKWSSKLTVHKVIHTG 687
>gi|210031219 zinc finger protein 845 [Homo sapiens]
Length = 970
Score = 113 bits (283), Expect = 2e-24
Identities = 168/742 (22%), Positives = 260/742 (35%), Gaps = 134/742 (18%)
Query: 1660 FRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCALCAYTNPIRKGLAAHYQKR 1719
++C C S + H+R+ +KC+ C T L H
Sbjct: 271 YKCNDCGKTFSQELTLTCHHRLHTGEKH---------YKCSECGKTFSRNSALVIHKAIH 321
Query: 1720 HDIDAYYTHCLAASRTISDKPNKVIIPSPPKDDSPQLSEELRRAVEKK------------ 1767
+Y C +T S V + P EE +A K
Sbjct: 322 TGEKSY--KCNECGKTFSQTSYLVYHRRLHTGEKPYKCEECDKAFSFKSNLERHRKIHTG 379
Query: 1768 ----KCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGYFTAVYADEH-------E 1816
KC+ CS ++FS+K ++ + + H G P K + G F+ + + + E
Sbjct: 380 EKPYKCNECS-RTFSRKSSLTRHRRLHTGEKPYK--CNDCGKTFSQMSSLVYHRRLHTGE 436
Query: 1817 KPTLMEEEERGNFEKAEVEGEAQ-EIEWLPFRCIKCFKLSFSTAELLCMHYTDHHSRDLK 1875
KP EE + K+ +E + P++C C K T+ L+ +H R
Sbjct: 437 KPYKCEECDEAFSFKSNLERHRRIHTGEKPYKCNDCGKTFSQTSSLV------YHRR--- 487
Query: 1876 RDFIILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHNEE----FQKRAKRQERRKQL 1931
+ G P Y+C+ CD + L H IH E + K R+ L
Sbjct: 488 ---LHTGEKP------YKCEECDEAFSFKSNLERHRIIHTGEKLYKCNECGKTFSRKSSL 538
Query: 1932 LSKQKYADGAFADFKQERPFGHLEEVPKIKERKVVG----YKCKFCVEVHPTLRAICNHL 1987
+ G E + I + + G YKC C +V I NH
Sbjct: 539 TRHCRLHTGEKPYQCNECGKAFRGQSALIYHQAIHGIGKLYKCNDCHQVFSNATTIANHW 598
Query: 1988 RKHVQYGNVPAVSAAVKGLRSHERSHLALAMFTR--EDKYSCQYCSFVSAFRHNLDRHMQ 2045
R H + + G RS+LA+ T E Y C+ C +F+ NL RH +
Sbjct: 599 RIHNEERSYKCNRC---GKFFRHRSYLAVHWRTHSGEKPYKCEECDEAFSFKSNLQRHRR 655
Query: 2046 THHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQL------- 2098
H G KP+RC C S S L H + H GE YKC+ C + S L
Sbjct: 656 IHTGE-KPYRCNECGKTFSRKSYLTCH-RRLHTGEKPYKCNECGKTFGRNSALIIHKAIH 713
Query: 2099 ---KEHSLKVHGKALTLPRPRIVSLLSSHSH-HSSQKATPAEEVEDSNDSSYSEPPDVQQ 2154
K + GKA + S L+ H H+ +K EE D +S +++
Sbjct: 714 TGEKPYKCNECGKAFSQK-----SSLTCHLRLHTGEKPYKCEEC----DKVFSRKSSLEK 764
Query: 2155 QLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKH 2214
+ E C+ C+ + G + +H R H
Sbjct: 765 HRRIHTG--------------------------EKPYKCKVCDKAFGRDSHLAQHTRI-H 797
Query: 2215 GGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIV 2274
G+K +KC +C SA +H +A HS G K +C C ++ + H
Sbjct: 798 TGEKPYKCNECGKNFRHNSALVIH-KAIHS-----GEKPYKCNECGKTFRHNSALEIHKA 851
Query: 2275 LHREERVVPIEVC------RSKLSKYLQ----GVVFRCDKCTFTCSSDESLQQHIEKHNE 2324
+H E+ C ++ LS++ + ++C+KC + L H H
Sbjct: 852 IHTGEKPYKCSECGKVFNRKANLSRHHRLHTGEKPYKCNKCGKVFNQQAHLACHHRIHTG 911
Query: 2325 LKPYKCQLCYYETKHTEELDSH 2346
KPYKC C +H L H
Sbjct: 912 EKPYKCNECGKTFRHNSVLVIH 933
Score = 112 bits (280), Expect = 5e-24
Identities = 146/663 (22%), Positives = 228/663 (34%), Gaps = 122/663 (18%)
Query: 1845 PFRCIKCFKLSFSTAELLCMHYTDHHSRDLK----------RDFIILGNGPRLQNSTYQC 1894
P++C C K L C H + K +++ +Y+C
Sbjct: 270 PYKCNDCGKTFSQELTLTCHHRLHTGEKHYKCSECGKTFSRNSALVIHKAIHTGEKSYKC 329
Query: 1895 KHCDSKLQSTAELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERPFGHL 1954
C T+ L H +H E K K +E K K ++ ++ R H
Sbjct: 330 NECGKTFSQTSYLVYHRRLHTGE--KPYKCEECDKAFSFK--------SNLERHRKI-HT 378
Query: 1955 EEVPKIKERKVVGYKCKFCVEVHPTLRAICNHLRKHV-----QYGNVPAVSAAVKGLRSH 2009
E P YKC C ++ H R H + + + + L H
Sbjct: 379 GEKP---------YKCNECSRTFSRKSSLTRHRRLHTGEKPYKCNDCGKTFSQMSSLVYH 429
Query: 2010 ERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRL 2069
R H T E Y C+ C +F+ NL+RH + H G KP++C C S S L
Sbjct: 430 RRLH------TGEKPYKCEECDEAFSFKSNLERHRRIHTGE-KPYKCNDCGKTFSQTSSL 482
Query: 2070 KTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVHGKAL--------TLPRPRIVSLL 2121
H + H GE YKC C + S L+ H + G+ L T R S L
Sbjct: 483 VYH-RRLHTGEKPYKCEECDEAFSFKSNLERHRIIHTGEKLYKCNECGKTFSRK---SSL 538
Query: 2122 SSHSH-HSSQKATPAEEVEDSNDSSYSEPPDVQQQLNH--------------YQSAALAR 2166
+ H H+ +K E + + + Q H + +A
Sbjct: 539 TRHCRLHTGEKPYQCNEC---GKAFRGQSALIYHQAIHGIGKLYKCNDCHQVFSNATTIA 595
Query: 2167 NNSRVSPVPLSG---------------AAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYR 2211
N+ R+ S A E CE C+ + + +++RH R
Sbjct: 596 NHWRIHNEERSYKCNRCGKFFRHRSYLAVHWRTHSGEKPYKCEECDEAFSFKSNLQRHRR 655
Query: 2212 DKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMID 2271
H G+K ++C +C KS T H G K +C C +I
Sbjct: 656 I-HTGEKPYRCNECGKTFSRKSYLTCHRRL------HTGEKPYKCNECGKTFGRNSALII 708
Query: 2272 HIVLHREERVVPIEVC------RSKLSKYLQ----GVVFRCDKCTFTCSSDESLQQHIEK 2321
H +H E+ C +S L+ +L+ ++C++C S SL++H
Sbjct: 709 HKAIHTGEKPYKCNECGKAFSQKSSLTCHLRLHTGEKPYKCEECDKVFSRKSSLEKHRRI 768
Query: 2322 HNELKPYKCQLCYYETKHTEELDSHLRDE--------HKVSRNFELVGRVNLDQLEQMKE 2373
H KPYKC++C L H R ++ +NF + + + E
Sbjct: 769 HTGEKPYKCKVCDKAFGRDSHLAQHTRIHTGEKPYKCNECGKNFRHNSALVIHKAIHSGE 828
Query: 2374 KMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHV 2433
K ++ K NS E H A EK + C CG+ F++ + RH
Sbjct: 829 K--PYKCNECGKTFRHNSALE--------IHKAIHTGEKPYKCSECGKVFNRKANLSRHH 878
Query: 2434 LRH 2436
H
Sbjct: 879 RLH 881
Score = 91.3 bits (225), Expect = 1e-17
Identities = 117/499 (23%), Positives = 176/499 (35%), Gaps = 93/499 (18%)
Query: 1975 EVHPTLRAI-CNHLRKHVQYGNVPAVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFV 2033
EVH ++ CN K Y +V LR H+ HL +Y C C V
Sbjct: 207 EVHMREKSFQCNESGKAFNYSSV---------LRKHQIIHLGAK------QYKCDVCGKV 251
Query: 2034 SAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTM 2093
+ L H + H G KP++C C S L H + H GE YKCS C +
Sbjct: 252 FNQKRYLACHRRCHTGK-KPYKCNDCGKTFSQELTLTCHH-RLHTGEKHYKCSECGKTFS 309
Query: 2094 TISQLKEH--------SLKVHGKALTLPRPRIVSLLSSHSH-HSSQKATPAEEVED--SN 2142
S L H S K + T + S L H H+ +K EE + S
Sbjct: 310 RNSALVIHKAIHTGEKSYKCNECGKTFSQ---TSYLVYHRRLHTGEKPYKCEECDKAFSF 366
Query: 2143 DSSYSEPPDVQQQLNHYQSAALARNNSRVS-------------PVPLSGAAAGTEQKTEA 2189
S+ + Y+ +R SR S P + Q +
Sbjct: 367 KSNLERHRKIHTGEKPYKCNECSRTFSRKSSLTRHRRLHTGEKPYKCNDCGKTFSQMSSL 426
Query: 2190 VLH-----------CEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMH 2238
V H CE C+ + + ++ RH R H G+K +KC DC S+ H
Sbjct: 427 VYHRRLHTGEKPYKCEECDEAFSFKSNLERH-RRIHTGEKPYKCNDCGKTFSQTSSLVYH 485
Query: 2239 VEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGV 2298
G K +C C +K N+ H ++H E+
Sbjct: 486 RRL------HTGEKPYKCEECDEAFSFKSNLERHRIIHTGEK------------------ 521
Query: 2299 VFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFE 2358
+++C++C T S SL +H H KPY+C C + L H + H + + ++
Sbjct: 522 LYKCNECGKTFSRKSSLTRHCRLHTGEKPYQCNECGKAFRGQSALIYH-QAIHGIGKLYK 580
Query: 2359 LVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAED-----RELMRFSDHGAALNTEKR 2413
+ Q+ + ++ EE + K R + H + EK
Sbjct: 581 ------CNDCHQVFSNATTIANHWRIHNEERSYKCNRCGKFFRHRSYLAVHWRTHSGEKP 634
Query: 2414 FPCEFCGRAFSQGSEWERH 2432
+ CE C AFS S +RH
Sbjct: 635 YKCEECDEAFSFKSNLQRH 653
Score = 84.7 bits (208), Expect = 1e-15
Identities = 147/664 (22%), Positives = 221/664 (33%), Gaps = 137/664 (20%)
Query: 1439 EQEAECPEDARLSPEKSLQLASANPAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPGMKV 1498
E+ +C E +R KS PY+C C ++ + L+ H + H G K
Sbjct: 380 EKPYKCNECSRTFSRKSSLTRHRRLHTGEKPYKCNDCGKTFSQMSSLVYHR-RLHTGEKP 438
Query: 1499 -------KAADFAQDID----INPGAV-YKCRHCPYINTRIHGVLTHYQKRHPSIKVTAE 1546
+A F +++ I+ G YKC C ++ ++ H ++ H T E
Sbjct: 439 YKCEECDEAFSFKSNLERHRRIHTGEKPYKCNDCGKTFSQTSSLVYH-RRLH-----TGE 492
Query: 1547 DFVHDVEQSADISQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFD 1606
E S E RI G Y+C C T L H +
Sbjct: 493 KPYKCEECDEAFSFKSNLERHRIIHTGEKLYKCNECGKTFSRKSSLTRHCRLH------- 545
Query: 1607 VFSQSPPKLPVPLEPEMTTEVSPSQVSITEEEVGEEPVSTSHFSTSHLVSHTVFRCQLCK 1666
T P Q + + + H + + +++C C
Sbjct: 546 ------------------TGEKPYQCNECGKAFRGQSALIYHQAIHGIGK--LYKCNDCH 585
Query: 1667 YFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCALCAYTNPIRKGLAAHYQKRHDIDAYY 1726
S IA H+RI HN R+ +KC C R LA H++ Y
Sbjct: 586 QVFSNATTIANHWRI-HNEERS--------YKCNRCGKFFRHRSYLAVHWRTHSGEKPY- 635
Query: 1727 THCLAASRTISDKPNKVIIPSPPKDDSPQLSEELRRAVEKKKCSLCSFQSFSKKGIVSHY 1786
C S K N Q + + +C+ C ++FS+K ++ +
Sbjct: 636 -KCEECDEAFSFKSNL------------QRHRRIHTGEKPYRCNECG-KTFSRKSYLTCH 681
Query: 1787 MKRHPGVFPKK-QHASKLGGYFTAVYADEHEKPTLMEEEERGNFEKAEVEGEAQEIEWLP 1845
+ H G P K K G +A+ KA GE P
Sbjct: 682 RRLHTGEKPYKCNECGKTFGRNSALI-----------------IHKAIHTGEK------P 718
Query: 1846 FRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQSTA 1905
++C +C K +FS L H H G P Y+C+ CD +
Sbjct: 719 YKCNECGK-AFSQKSSLTCHLRLH-----------TGEKP------YKCEECDKVFSRKS 760
Query: 1906 ELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVPKIKERKV 1965
L H IH E + K ++ A G + Q H E P
Sbjct: 761 SLEKHRRIHTGEKPYKCKVCDK----------AFGRDSHLAQHTRI-HTGEKP------- 802
Query: 1966 VGYKCKFCVEVHPTLRAICNHLRKHVQYGNVP-AVSAAVKGLRSHERSHLALAMFTREDK 2024
YKC C + A+ H K + G P + K R + + A+ T E
Sbjct: 803 --YKCNECGKNFRHNSALVIH--KAIHSGEKPYKCNECGKTFRHNSALEIHKAIHTGEKP 858
Query: 2025 YSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYK 2084
Y C C V + NL RH + H G KP++C C + + L H + H GE YK
Sbjct: 859 YKCSECGKVFNRKANLSRHHRLHTG-EKPYKCNKCGKVFNQQAHLACH-HRIHTGEKPYK 916
Query: 2085 CSWC 2088
C+ C
Sbjct: 917 CNEC 920
Score = 38.1 bits (87), Expect = 0.11
Identities = 47/234 (20%), Positives = 78/234 (33%), Gaps = 30/234 (12%)
Query: 2205 SIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTK 2264
S+ ++ H +K F+C + + S H + G K +C +C
Sbjct: 200 SLLTQKQEVHMREKSFQCNESGKAFNYSSVLRKH------QIIHLGAKQYKCDVCGKVFN 253
Query: 2265 YKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRCDKCTFTCSSDESLQQHIEKHNE 2324
KR + H H ++ ++C+ C T S + +L H H
Sbjct: 254 QKRYLACHRRCHTGKKP------------------YKCNDCGKTFSQELTLTCHHRLHTG 295
Query: 2325 LKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFEL--VGRVNLDQLEQMKEKMESSSSDD 2382
K YKC C L H + H ++++ G+ Q + + +
Sbjct: 296 EKHYKCSECGKTFSRNSALVIH-KAIHTGEKSYKCNECGK-TFSQTSYLVYHRRLHTGEK 353
Query: 2383 EDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRH 2436
K EE + + H EK + C C R FS+ S RH H
Sbjct: 354 PYKCEECDKAFSFKS--NLERHRKIHTGEKPYKCNECSRTFSRKSSLTRHRRLH 405
Score = 34.7 bits (78), Expect = 1.2
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 2/42 (4%)
Query: 453 SISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
S+ R + IHL K YKCD C L H++CHTG
Sbjct: 228 SVLRKHQIIHLGAKQ--YKCDVCGKVFNQKRYLACHRRCHTG 267
Score = 33.9 bits (76), Expect = 2.1
Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C + ++ RH IH K YKC+EC T L H++ HTG
Sbjct: 355 YKCEECDKAFSFKSNLERH-RKIHTGEKP--YKCNECSRTFSRKSSLTRHRRLHTG 407
Score = 32.3 bits (72), Expect = 6.0
Identities = 41/185 (22%), Positives = 67/185 (36%), Gaps = 39/185 (21%)
Query: 312 IPNTTVSNFRGSMGNSIMRPNSSASKFSPMSYPQMKPKSPHNSGLVNLTERSRYGMTDMT 371
+P + G +GN + + +SAS S +PK+ H S YG +
Sbjct: 148 LPELHMFQTEGKIGNQVEKSINSASLVSTSQRISCRPKT-HIS--------KNYGNNFLN 198
Query: 372 NSSADLETNSMLNDSSSDEELNEIDSENGLSAM--DHQTSGLSAEQLMGSDGNKLLETKG 429
+S + + + S + NE S++ HQ L A+Q
Sbjct: 199 SSLLTQKQEVHMREKSF--QCNESGKAFNYSSVLRKHQIIHLGAKQ-------------- 242
Query: 430 IPFRRFMNRFQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHK 489
++C C + +R ++ H H K YKC++C T L L H
Sbjct: 243 ---------YKCDVCGKVFNQKRYLACH-RRCHTGKKP--YKCNDCGKTFSQELTLTCHH 290
Query: 490 QCHTG 494
+ HTG
Sbjct: 291 RLHTG 295
Score = 32.3 bits (72), Expect = 6.0
Identities = 17/56 (30%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C + S++RH +H K YKC++C T L H++ HTG
Sbjct: 383 YKCNECSRTFSRKSSLTRH-RRLHTGEKP--YKCNDCGKTFSQMSSLVYHRRLHTG 435
Score = 32.3 bits (72), Expect = 6.0
Identities = 17/56 (30%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C + ++ RH IH K YKC++C T + L H++ HTG
Sbjct: 439 YKCEECDEAFSFKSNLERH-RRIHTGEKP--YKCNDCGKTFSQTSSLVYHRRLHTG 491
Score = 32.3 bits (72), Expect = 6.0
Identities = 53/260 (20%), Positives = 87/260 (33%), Gaps = 28/260 (10%)
Query: 1439 EQEAECPEDARLSPEKSLQLASANPAISSTPYQCTVCQSEYNNLHGL----LTHYGKKHP 1494
E+ +C E + +KS PY+C C ++ L H G+K
Sbjct: 716 EKPYKCNECGKAFSQKSSLTCHLRLHTGEKPYKCEECDKVFSRKSSLEKHRRIHTGEKPY 775
Query: 1495 GMKV------KAADFAQDIDINPG-AVYKCRHCPYINTRIHGVLTHYQKRHPSIKVTAED 1547
KV + + AQ I+ G YKC C N R + L ++ H + E
Sbjct: 776 KCKVCDKAFGRDSHLAQHTRIHTGEKPYKCNECGK-NFRHNSALVIHKAIH-----SGEK 829
Query: 1548 FVHDVEQSADISQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEF-- 1605
E N E + G Y+C C L H+ + + +
Sbjct: 830 PYKCNECGKTFRHNSALEIHKAIHTGEKPYKCSECGKVFNRKANLSRHHRLHTGEKPYKC 889
Query: 1606 ----DVFSQSPPKLPVPLEPEMTTEVSPSQVSITEEEVGEEPVSTSHFSTSHLVSHTVFR 1661
VF+Q + + + T P + + + V H T H ++
Sbjct: 890 NKCGKVFNQ---QAHLACHHRIHTGEKPYKCNECGKTFRHNSVLVIH-KTIH-TGEKPYK 944
Query: 1662 CQLCKYFCSTRKGIARHYRI 1681
C C + + +ARH+RI
Sbjct: 945 CNECGKVFNRKAKLARHHRI 964
Score = 32.0 bits (71), Expect = 7.9
Identities = 21/78 (26%), Positives = 34/78 (43%), Gaps = 7/78 (8%)
Query: 421 GNKLLETKGIPFRRFMNR----FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECP 476
G +T + + R ++ ++C C + ++ RH IH K +YKC+EC
Sbjct: 473 GKTFSQTSSLVYHRRLHTGEKPYKCEECDEAFSFKSNLERH-RIIHTGEK--LYKCNECG 529
Query: 477 FTCKSSLKLGAHKQCHTG 494
T L H + HTG
Sbjct: 530 KTFSRKSSLTRHCRLHTG 547
Score = 32.0 bits (71), Expect = 7.9
Identities = 17/56 (30%), Positives = 26/56 (46%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C + ++ RH IH K Y+C+EC T L H++ HTG
Sbjct: 635 YKCEECDEAFSFKSNLQRH-RRIHTGEKP--YRCNECGKTFSRKSYLTCHRRLHTG 687
>gi|157167158 zinc finger protein 808 [Homo sapiens]
Length = 903
Score = 113 bits (283), Expect = 2e-24
Identities = 155/668 (23%), Positives = 233/668 (34%), Gaps = 120/668 (17%)
Query: 1845 PFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQST 1904
P++C +C K SFS L H+ H G P Y+C C +
Sbjct: 286 PYKCKECGK-SFSYKSSLTCHHRLH-----------TGVKP------YKCNECGKVFRQN 327
Query: 1905 AELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVPKIKERK 1964
+ L H IH E K K E K F Q+ HL ++
Sbjct: 328 SALVIHKAIHTGE--KPYKCNECGKA--------------FNQQ---SHLSRHQRL-HTG 367
Query: 1965 VVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVPA--VSAAVKGLRSHERSHLALAMFTRE 2022
V YKCK C + + NH R H A S R H+ + T E
Sbjct: 368 VKPYKCKICEKAFACHSYLANHTRIHSGEKTYKCNECGKAFNHQSSLARHHI---LHTGE 424
Query: 2023 DKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHA 2082
Y C+ C V + + L+RH + H G KP++CK+C + NS+L H + H GE
Sbjct: 425 KPYKCEECDKVFSQKSTLERHKRIHTGE-KPYKCKVCDTAFTCNSQLARH-RRIHTGEKT 482
Query: 2083 YKCSWCSFSTMTISQLKEHSLKVHGKA---------LTLPRPRIVSLLSSHSHHSSQKAT 2133
YKC+ C + S L H G+ R +V H+ S K T
Sbjct: 483 YKCNECRKTFSRRSSLLCHRRLHSGEKPYKCNQCGNTFRHRASLVYHRRLHTLEKSYKCT 542
Query: 2134 PAEEVEDSND--------SSYSEPPDVQQQLNHY-QSAALARN---NSRVSPVPLSGAAA 2181
+V N + +P + + Q + L+R+ ++ P
Sbjct: 543 VCNKVFMRNSVLAVHTRIHTAKKPYKCNECGKAFNQQSHLSRHRRLHTGEKPYKCEACDK 602
Query: 2182 GTEQKTEAVLH-----------CEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTG 2230
QK+ H C+ C+ + + + RH R H G+K +KC +C
Sbjct: 603 VFGQKSALESHKRIHTGEKPYRCQVCDTAFTWNSQLARHTRI-HTGEKTYKCNECGKTFS 661
Query: 2231 FKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSK 2290
+KS+ H G K +C +C + + H +H + C
Sbjct: 662 YKSSLVWHRRL------HGGEKSYKCKVCDKAFVCRSYVAKHTRIHSGMKPYKCNECSKT 715
Query: 2291 LSKYLQGVV----------FRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHT 2340
S V ++C +C+ T S +L H H+ KPYKC C +H
Sbjct: 716 FSNRSSLVCHRRIHSGEKPYKCSECSKTFSQKATLLCHRRLHSGEKPYKCNDCGNTFRHW 775
Query: 2341 EELDSHLR-----DEHKVS-------RNFELVGRVNLDQLEQMKEKMESSSSDDEDK--- 2385
L H R +K + RN L + + E+ + E + +E
Sbjct: 776 SSLVYHRRLHTGEKSYKCTVCDKAFVRNSYLARHIRIHTAEKPYKCNECGKAFNEQSHLS 835
Query: 2386 --------EEEMNSKAEDRELMRFSD---HGAALNTEKRFPCEFCGRAFSQGSEWERHVL 2434
E+ +A D+ R S H EK + C CG+AFS S H
Sbjct: 836 RHHRIHTGEKPYKCEACDKVFSRKSHLKRHRIIHTGEKPYKCNECGKAFSDRSTLIHHQA 895
Query: 2435 RHGMALND 2442
HG+ D
Sbjct: 896 IHGIGKFD 903
Score = 110 bits (274), Expect = 2e-23
Identities = 155/712 (21%), Positives = 247/712 (34%), Gaps = 128/712 (17%)
Query: 1660 FRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCALCAYTNPIRKGLAAHYQKR 1719
++C +C + ++ +A H R H + +KC C + + L H++
Sbjct: 259 YKCDVCGKLFNHKQYLACHRRC-HTGEKP--------YKCKECGKSFSYKSSLTCHHRLH 309
Query: 1720 HDIDAYYTHCLAASRTISDKPNKVIIPSPPKDDSPQLSEELRRAVEKKKCSLCSFQSFSK 1779
+ Y C + VI + + P KC+ C ++F++
Sbjct: 310 TGVKPY--KCNECGKVFRQNSALVIHKAIHTGEKPY------------KCNECG-KAFNQ 354
Query: 1780 KGIVSHYMKRHPGVFPKK----QHASKLGGYFTAVYADEHEKPTLMEEEERG---NFEKA 1832
+ +S + + H GV P K + A Y A + H + E G N + +
Sbjct: 355 QSHLSRHQRLHTGVKPYKCKICEKAFACHSYL-ANHTRIHSGEKTYKCNECGKAFNHQSS 413
Query: 1833 EVEGEAQEIEWLPFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQNSTY 1892
P++C +C K+ FS L H H G P Y
Sbjct: 414 LARHHILHTGEKPYKCEECDKV-FSQKSTLERHKRIH-----------TGEKP------Y 455
Query: 1893 QCKHCDSKLQSTAELTSHLNIHNEEFQKRA----KRQERRKQLLSKQKYADGA--FADFK 1946
+CK CD+ ++L H IH E + K RR LL ++ G + +
Sbjct: 456 KCKVCDTAFTCNSQLARHRRIHTGEKTYKCNECRKTFSRRSSLLCHRRLHSGEKPYKCNQ 515
Query: 1947 QERPFGHLEEVPKIKERKVV--GYKCKFCVEVHPTLRAICNHLRKHVQYGNVPAVSAAVK 2004
F H + + + YKC C +V + H R H
Sbjct: 516 CGNTFRHRASLVYHRRLHTLEKSYKCTVCNKVFMRNSVLAVHTRIHTAKKPYKCNEC--- 572
Query: 2005 GLRSHERSHLAL--AMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFK 2062
G +++SHL+ + T E Y C+ C V + L+ H + H G KP+RC++C
Sbjct: 573 GKAFNQQSHLSRHRRLHTGEKPYKCEACDKVFGQKSALESHKRIHTGE-KPYRCQVCDTA 631
Query: 2063 SSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQL----------KEHSLKVHGKALTL 2112
++NS+L H + H GE YKC+ C + S L K + KV KA
Sbjct: 632 FTWNSQLARH-TRIHTGEKTYKCNECGKTFSYKSSLVWHRRLHGGEKSYKCKVCDKAFVC 690
Query: 2113 PRPRIVSLLSSHSH-HSSQKATPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNSRV 2171
S ++ H+ HS K E + N R +S
Sbjct: 691 R-----SYVAKHTRIHSGMKPYKCNECSKTFS-------------NRSSLVCHRRIHSGE 732
Query: 2172 SPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGF 2231
P S + QK + H R H G+K +KC DC
Sbjct: 733 KPYKCSECSKTFSQKATLLCH------------------RRLHSGEKPYKCNDCGNTFRH 774
Query: 2232 KSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVC---- 2287
S+ H G K +C +C + HI +H E+ C
Sbjct: 775 WSSLVYHRRL------HTGEKSYKCTVCDKAFVRNSYLARHIRIHTAEKPYKCNECGKAF 828
Query: 2288 --RSKLSKYLQ----GVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLC 2333
+S LS++ + ++C+ C S L++H H KPYKC C
Sbjct: 829 NEQSHLSRHHRIHTGEKPYKCEACDKVFSRKSHLKRHRIIHTGEKPYKCNEC 880
Score = 80.5 bits (197), Expect = 2e-14
Identities = 156/746 (20%), Positives = 256/746 (34%), Gaps = 152/746 (20%)
Query: 1439 EQEAECPEDARLSPEKSLQLASANPAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPGMK- 1497
E+ C E + SL P + Y+C VC +N+ L H + H G K
Sbjct: 228 EKSFPCNESGKAFNCSSLLRKHQIPHLGDKQYKCDVCGKLFNHKQYLACH-RRCHTGEKP 286
Query: 1498 VKAADFAQDIDINPGAV-----------YKCRHCPYINTRIHGVLTH------------- 1533
K + + YKC C + + ++ H
Sbjct: 287 YKCKECGKSFSYKSSLTCHHRLHTGVKPYKCNECGKVFRQNSALVIHKAIHTGEKPYKCN 346
Query: 1534 ----------YQKRHPSIKVTAEDFVHDVEQSADISQNDVEETSRIFKQGYGAYRCKLCP 1583
+ RH + + + + + A + + +RI G Y+C C
Sbjct: 347 ECGKAFNQQSHLSRHQRLHTGVKPYKCKICEKAFACHSYLANHTRI-HSGEKTYKCNECG 405
Query: 1584 YTHGTLEKLKIHY-----EKYHNQPEFD-VFSQSPPKLPVPLEPEMTTEVSPSQVSITEE 1637
L H+ EK + E D VFSQ K + + T P + + +
Sbjct: 406 KAFNHQSSLARHHILHTGEKPYKCEECDKVFSQ---KSTLERHKRIHTGEKPYKCKVCD- 461
Query: 1638 EVGEEPVSTSHFSTSHLVSH-------TVFRCQLCKYFCSTRKGIARHYRIKHNNVRAQP 1690
T+ S L H ++C C+ S R + H R+ H+ +
Sbjct: 462 --------TAFTCNSQLARHRRIHTGEKTYKCNECRKTFSRRSSLLCHRRL-HSGEKP-- 510
Query: 1691 EGKNNLFKCALCAYTNPIRKGLAAHYQKRHDIDAYY--THCLAASRTISDKPNKVIIPSP 1748
+KC C T R L H ++ H ++ Y T C NKV +
Sbjct: 511 ------YKCNQCGNTFRHRASLVYH-RRLHTLEKSYKCTVC-----------NKVFM--- 549
Query: 1749 PKDDSPQLSEELRRAVEKKKCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHA-SKLGGYF 1807
++ + + A + KC+ C ++F+++ +S + + H G P K A K+ G
Sbjct: 550 -RNSVLAVHTRIHTAKKPYKCNECG-KAFNQQSHLSRHRRLHTGEKPYKCEACDKVFGQK 607
Query: 1808 TAVYADEH----EKPTLMEEEERGNFEKAEVEGEAQ-EIEWLPFRCIKCFKLSFSTAELL 1862
+A+ + + EKP + + +++ + ++C +C K +FS L
Sbjct: 608 SALESHKRIHTGEKPYRCQVCDTAFTWNSQLARHTRIHTGEKTYKCNECGK-TFSYKSSL 666
Query: 1863 CMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHN----EEF 1918
H H +Y+CK CD + + H IH+ +
Sbjct: 667 VWHRRLHGG-----------------EKSYKCKVCDKAFVCRSYVAKHTRIHSGMKPYKC 709
Query: 1919 QKRAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVPKIKERKVV------------ 1966
+ +K R L+ ++ G E+P+ E K +K
Sbjct: 710 NECSKTFSNRSSLVCHRRIHSG-------EKPY-KCSECSKTFSQKATLLCHRRLHSGEK 761
Query: 1967 GYKCKFCVEVHPTLRAICNHLRKHV---QYGNVPAVSAAVKG--LRSHERSHLALAMFTR 2021
YKC C ++ H R H Y A V+ L H R H T
Sbjct: 762 PYKCNDCGNTFRHWSSLVYHRRLHTGEKSYKCTVCDKAFVRNSYLARHIRIH------TA 815
Query: 2022 EDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEH 2081
E Y C C + +L RH + H G KP++C+ C S S LK H + H GE
Sbjct: 816 EKPYKCNECGKAFNEQSHLSRHHRIHTG-EKPYKCEACDKVFSRKSHLKRHRI-IHTGEK 873
Query: 2082 AYKCSWCSFSTMTISQLKEHSLKVHG 2107
YKC+ C + S L H +HG
Sbjct: 874 PYKCNECGKAFSDRSTLIHHQ-AIHG 898
Score = 58.5 bits (140), Expect = 8e-08
Identities = 54/242 (22%), Positives = 91/242 (37%), Gaps = 31/242 (12%)
Query: 2193 CEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPK 2252
C+ C + Q + H R H G+K +KCK+C +KS+ T H G K
Sbjct: 261 CDVCGKLFNHKQYLACHRRC-HTGEKPYKCKECGKSFSYKSSLTCHHRL------HTGVK 313
Query: 2253 DLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRCDKCTFTCSSD 2312
+C C + ++ H +H E+ ++C++C +
Sbjct: 314 PYKCNECGKVFRQNSALVIHKAIHTGEKP------------------YKCNECGKAFNQQ 355
Query: 2313 ESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFEL--VGRVNLDQLEQ 2370
L +H H +KPYKC++C L +H R H + ++ G+ Q
Sbjct: 356 SHLSRHQRLHTGVKPYKCKICEKAFACHSYLANHTR-IHSGEKTYKCNECGKAFNHQSSL 414
Query: 2371 MKEKMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWE 2430
+ + + EE ++ L R H EK + C+ C AF+ S+
Sbjct: 415 ARHHILHTGEKPYKCEECDKVFSQKSTLER---HKRIHTGEKPYKCKVCDTAFTCNSQLA 471
Query: 2431 RH 2432
RH
Sbjct: 472 RH 473
Score = 37.4 bits (85), Expect = 0.19
Identities = 37/154 (24%), Positives = 52/154 (33%), Gaps = 34/154 (22%)
Query: 2287 CRSKLSKY----LQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEE 2342
C S L K+ L ++CD C + + L H H KPYKC+ C +
Sbjct: 242 CSSLLRKHQIPHLGDKQYKCDVCGKLFNHKQYLACHRRCHTGEKPYKCKECGKSFSYKSS 301
Query: 2343 LDSHLRDEHKVSRNFELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDRELMRFS 2402
L H R + ++ ++ K NS
Sbjct: 302 LTCHHR----------------------LHTGVKPYKCNECGKVFRQNS--------ALV 331
Query: 2403 DHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRH 2436
H A EK + C CG+AF+Q S RH H
Sbjct: 332 IHKAIHTGEKPYKCNECGKAFNQQSHLSRHQRLH 365
Score = 35.0 bits (79), Expect = 0.93
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C H+ S++RH +H K YKC+EC L HK+ HTG
Sbjct: 399 YKCNECGKAFNHQSSLARH-HILHTGEKP--YKCEECDKVFSQKSTLERHKRIHTG 451
Score = 34.3 bits (77), Expect = 1.6
Identities = 41/181 (22%), Positives = 68/181 (37%), Gaps = 22/181 (12%)
Query: 1439 EQEAECPEDARLSPEKSLQLASANPAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPGMK- 1497
E+ +C E ++ +K+ L PY+C C + + + L+ H + H G K
Sbjct: 732 EKPYKCSECSKTFSQKATLLCHRRLHSGEKPYKCNDCGNTFRHWSSLVYH-RRLHTGEKS 790
Query: 1498 ----------VKAADFAQDIDINPG-AVYKCRHC-PYINTRIHGVLTHYQKRHPSIKVTA 1545
V+ + A+ I I+ YKC C N + H L+ + + H K
Sbjct: 791 YKCTVCDKAFVRNSYLARHIRIHTAEKPYKCNECGKAFNEQSH--LSRHHRIHTGEKPYK 848
Query: 1546 EDFVHDVEQSADISQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEF 1605
+ V S+ + RI G Y+C C L IH++ H +F
Sbjct: 849 CEACDKV-----FSRKSHLKRHRIIHTGEKPYKCNECGKAFSDRSTL-IHHQAIHGIGKF 902
Query: 1606 D 1606
D
Sbjct: 903 D 903
Score = 33.5 bits (75), Expect = 2.7
Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C + ++RHI IH + K YKC+EC L H + HTG
Sbjct: 791 YKCTVCDKAFVRNSYLARHIR-IHTAEKP--YKCNECGKAFNEQSHLSRHHRIHTG 843
Score = 33.1 bits (74), Expect = 3.5
Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C ++RH IH KT YKC+EC T L H++ H+G
Sbjct: 455 YKCKVCDTAFTCNSQLARH-RRIHTGEKT--YKCNECRKTFSRRSSLLCHRRLHSG 507
Score = 32.0 bits (71), Expect = 7.9
Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 3/59 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTGTTS 497
++C C ++RH IH KT YKC+EC T L H++ H G S
Sbjct: 623 YRCQVCDTAFTWNSQLARHTR-IHTGEKT--YKCNECGKTFSYKSSLVWHRRLHGGEKS 678
Score = 32.0 bits (71), Expect = 7.9
Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C + R +++H IH K YKC+EC T + L H++ H+G
Sbjct: 679 YKCKVCDKAFVCRSYVAKHTR-IHSGMKP--YKCNECSKTFSNRSSLVCHRRIHSG 731
>gi|162417982 zinc finger protein 64 isoform d [Homo sapiens]
Length = 645
Score = 113 bits (282), Expect = 3e-24
Identities = 107/429 (24%), Positives = 178/429 (41%), Gaps = 44/429 (10%)
Query: 2022 EDKYSCQY--CSFVSAF-RHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHA 2078
+ + +C Y C F +A+ +++RH++ H G KP +C++C S +LKTH ++ H
Sbjct: 141 QKRLNCCYPGCQFKTAYGMKDMERHLKIHTGD-KPHKCEVCGKCFSRKDKLKTH-MRCHT 198
Query: 2079 GEHAYKCSWCSFSTMTISQLKEHSLKVHGKALTLPRPRIVSLLSSHSHHSSQKATPAEEV 2138
G YKC C ++ S L +H L++H RP + S +SSQ
Sbjct: 199 GVKPYKCKTCDYAAADSSSLNKH-LRIHSD----ERPFKCQICPYASRNSSQLTV----- 248
Query: 2139 EDSNDSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEF--C 2196
+ SE D + N + + + V +P S A E +C + C
Sbjct: 249 -HLRSHTASELDDDVPKANCLSTESTDTPKAPVITLP-SEAREQMATLGERTFNCCYPGC 306
Query: 2197 EFSSGY-IQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLR 2255
F + + ++ + RH R H G K KC+ C K TMH+ S P +
Sbjct: 307 HFKTVHGMKDLDRHLR-IHTGDKPHKCEFCDKCFSRKDNLTMHMRCHTSVKPH------K 359
Query: 2256 CPLCLYHTKYKRNMIDHIVLHREERVVPIEVC------RSKLSKYLQG----VVFRCDKC 2305
C LC Y ++ H+ +H +ER ++C S+L+ +L+ F+C C
Sbjct: 360 CHLCDYAAVDSSSLKKHLRIHSDERPYKCQLCPYASRNSSQLTVHLRSHTGDTPFQCWLC 419
Query: 2306 TFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVS-RNFELVGRVN 2364
+ L++H+ H+ KP+KC+ C L SH+R +H + GR
Sbjct: 420 SAKFKISSDLKRHMIVHSGEKPFKCEFCDVRCTMKANLKSHIRIKHTFKCLHCAFQGRDR 479
Query: 2365 LDQLEQMKEKMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFS 2424
D LE + +D +K E + +R H ++ F C+FC
Sbjct: 480 ADLLEHSR----LHQADHPEKCPECSYSCSSAAALRV--HSRVHCKDRPFKCDFCSFDTK 533
Query: 2425 QGSEWERHV 2433
+ S +HV
Sbjct: 534 RPSSLAKHV 542
Score = 105 bits (262), Expect = 6e-22
Identities = 118/562 (20%), Positives = 187/562 (33%), Gaps = 179/562 (31%)
Query: 1892 YQCKHCDSKLQSTAELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERPF 1951
Y+CK CD ++ L HL IH++ ERPF
Sbjct: 203 YKCKTCDYAAADSSSLNKHLRIHSD-------------------------------ERPF 231
Query: 1952 GHLEEVPKIKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQY---GNVPAVS-------- 2000
KC+ C + HLR H +VP +
Sbjct: 232 -----------------KCQICPYASRNSSQLTVHLRSHTASELDDDVPKANCLSTESTD 274
Query: 2001 ---AAVKGLRSHERSHLALAMFTREDKYSCQY--CSFVSAF-RHNLDRHMQTHHGHHKPF 2054
A V L S R +A E ++C Y C F + +LDRH++ H G KP
Sbjct: 275 TPKAPVITLPSEAREQMATL---GERTFNCCYPGCHFKTVHGMKDLDRHLRIHTGD-KPH 330
Query: 2055 RCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVHGKALTLPR 2114
+C+ C S L H ++ H +KC C ++ + S LK+H L++H R
Sbjct: 331 KCEFCDKCFSRKDNLTMH-MRCHTSVKPHKCHLCDYAAVDSSSLKKH-LRIHSDE----R 384
Query: 2115 PRIVSLLSSHSHHSSQKATPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNSRVSPV 2174
P L S +SSQ H +S
Sbjct: 385 PYKCQLCPYASRNSSQLTV------------------------HLRS------------- 407
Query: 2175 PLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSA 2234
+ C C ++RH H G+K FKC+ C K+
Sbjct: 408 ----------HTGDTPFQCWLCSAKFKISSDLKRHMI-VHSGEKPFKCEFCDVRCTMKAN 456
Query: 2235 FTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKY 2294
H+ H+ +C C + + + ++++H LH+ +
Sbjct: 457 LKSHIRIKHT---------FKCLHCAFQGRDRADLLEHSRLHQADHPE------------ 495
Query: 2295 LQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVS 2354
+C +C+++CSS +L+ H H + +P+KC C ++TK L H+ H+
Sbjct: 496 ------KCPECSYSCSSAAALRVHSRVHCKDRPFKCDFCSFDTKRPSSLAKHVDKVHR-- 547
Query: 2355 RNFELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEKRF 2414
DE K E ++ S H A + T++ F
Sbjct: 548 ---------------------------DEAKTENRAPLGKEGLREGSSQHVAKIVTQRAF 580
Query: 2415 PCEFCGRAFSQGSEWERHVLRH 2436
CE CG +F + H +H
Sbjct: 581 RCETCGASFVRDDSLRCHKKQH 602
Score = 89.7 bits (221), Expect = 3e-17
Identities = 115/564 (20%), Positives = 207/564 (36%), Gaps = 167/564 (29%)
Query: 1652 SHLVSHT---VFRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCALCAY---- 1704
+H+ HT ++C+ C Y + + +H RI H++ R FKC +C Y
Sbjct: 192 THMRCHTGVKPYKCKTCDYAAADSSSLNKHLRI-HSDERP--------FKCQICPYASRN 242
Query: 1705 TNPIRKGLAAHYQKRHDIDAYYTHCLAASRTISDKPNKVIIPSPPKDDSPQLSEE----- 1759
++ + L +H D D +CL+ T + K + +PS ++ L E
Sbjct: 243 SSQLTVHLRSHTASELDDDVPKANCLSTESTDTPKAPVITLPSEAREQMATLGERTFNCC 302
Query: 1760 --------------------LRRAVEKKKCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQH 1799
+ + KC C + FS+K ++ +M+ H V P K H
Sbjct: 303 YPGCHFKTVHGMKDLDRHLRIHTGDKPHKCEFCD-KCFSRKDNLTMHMRCHTSVKPHKCH 361
Query: 1800 ASKLGGYFTAVYADEHEKPTLMEEEERGNFEKAEVEGEAQEIEWLPFRCIKCFKLSFSTA 1859
+ AV + +K + +ER P++C C S +++
Sbjct: 362 LCD----YAAVDSSSLKKHLRIHSDER------------------PYKCQLCPYASRNSS 399
Query: 1860 ELLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHNEEFQ 1919
+ L +H H G+ P +QC C +K + +++L H+ +H+
Sbjct: 400 Q-LTVHLRSH-----------TGDTP------FQCWLCSAKFKISSDLKRHMIVHS---- 437
Query: 1920 KRAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVPKIKERKVVGYKCKFCVEVHPT 1979
E+PF KC+FC +V T
Sbjct: 438 ---------------------------GEKPF-----------------KCEFC-DVRCT 452
Query: 1980 LRAICNHLRKHVQYGNVPAVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHN 2039
++A +L+ H++ + + C +C+F R +
Sbjct: 453 MKA---NLKSHIRI----------------------------KHTFKCLHCAFQGRDRAD 481
Query: 2040 LDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLK 2099
L H + H H P +C CS+ S + L+ H + H + +KC +CSF T S L
Sbjct: 482 LLEHSRLHQADH-PEKCPECSYSCSSAAALRVH-SRVHCKDRPFKCDFCSFDTKRPSSLA 539
Query: 2100 EHSLKVH-GKALTLPRPRI--VSLLSSHSHHSSQKATPAEEVEDSNDSSYSEPPDVQQQL 2156
+H KVH +A T R + L S H ++ T ++ +S+ ++
Sbjct: 540 KHVDKVHRDEAKTENRAPLGKEGLREGSSQHVAKIVTQRAFRCETCGASFVRDDSLRCHK 599
Query: 2157 NHYQSAALARNNSRVSPVPLSGAA 2180
+ + +N+ V+ P SGA+
Sbjct: 600 KQHSDQSENKNSDLVTFPPESGAS 623
Score = 77.4 bits (189), Expect = 2e-13
Identities = 128/573 (22%), Positives = 204/573 (35%), Gaps = 160/573 (27%)
Query: 1768 KCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGYFTAVYADEHEKPTLMEEEERG 1827
KC +C + FS+K + +M+ H GV P K + A + K + +ER
Sbjct: 176 KCEVCG-KCFSRKDKLKTHMRCHTGVKPYKCKTCD----YAAADSSSLNKHLRIHSDER- 229
Query: 1828 NFEKAEVEGEAQEIEWLPFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRL 1887
PF+C C S ++++ L +H H + +L D P+
Sbjct: 230 -----------------PFKCQICPYASRNSSQ-LTVHLRSHTASELDDDV------PK- 264
Query: 1888 QNSTYQCKHCDSKLQSTAELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQ 1947
+C S + + + +E ++ A ER F
Sbjct: 265 -------ANCLSTESTDTPKAPVITLPSEAREQMATLGER----------------TFNC 301
Query: 1948 ERPFGHLEEVPKIKE-----RKVVG---YKCKFCVEVHPTLRAICNHLRKHVQYG----- 1994
P H + V +K+ R G +KC+FC + + H+R H
Sbjct: 302 CYPGCHFKTVHGMKDLDRHLRIHTGDKPHKCEFCDKCFSRKDNLTMHMRCHTSVKPHKCH 361
Query: 1995 --NVPAVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHK 2052
+ AV ++ L+ H R H + E Y CQ C + S L H+++H G
Sbjct: 362 LCDYAAVDSS--SLKKHLRIH------SDERPYKCQLCPYASRNSSQLTVHLRSHTG-DT 412
Query: 2053 PFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEH-SLKVHGKALT 2111
PF+C LCS K +S LK H++ H+GE +KC +C + LK H +K K L
Sbjct: 413 PFQCWLCSAKFKISSDLKRHMI-VHSGEKPFKCEFCDVRCTMKANLKSHIRIKHTFKCL- 470
Query: 2112 LPRPRIVSLLSSHSHHSSQKATPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNSRV 2171
H + Q A+ +E S P + SAA R +SRV
Sbjct: 471 --------------HCAFQGRDRADLLEHSRLHQADHPEKCPECSYSCSSAAALRVHSRV 516
Query: 2172 SPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGF 2231
HC+ + FKC CSF T
Sbjct: 517 --------------------HCK----------------------DRPFKCDFCSFDTKR 534
Query: 2232 KSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKL 2291
S+ HV+ H +E + R PL K + + H +
Sbjct: 535 PSSLAKHVDKVHR---DEAKTENRAPL------GKEGLREGSSQH--------------V 571
Query: 2292 SKYLQGVVFRCDKCTFTCSSDESLQQHIEKHNE 2324
+K + FRC+ C + D+SL+ H ++H++
Sbjct: 572 AKIVTQRAFRCETCGASFVRDDSLRCHKKQHSD 604
Score = 67.4 bits (163), Expect = 2e-10
Identities = 53/212 (25%), Positives = 93/212 (43%), Gaps = 28/212 (13%)
Query: 2252 KDLRC--PLCLYHTKY-KRNMIDHIVLHREERVVPIEVC------RSKLSKYLQ---GVV 2299
K L C P C + T Y ++M H+ +H ++ EVC + KL +++ GV
Sbjct: 142 KRLNCCYPGCQFKTAYGMKDMERHLKIHTGDKPHKCEVCGKCFSRKDKLKTHMRCHTGVK 201
Query: 2300 -FRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFE 2358
++C C + + SL +H+ H++ +P+KCQ+C Y ++++ +L HLR H S +
Sbjct: 202 PYKCKTCDYAAADSSSLNKHLRIHSDERPFKCQICPYASRNSSQLTVHLR-SHTASELDD 260
Query: 2359 LVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDR-------------ELMRFSDHG 2405
V + N E + + E+M + E M+ D
Sbjct: 261 DVPKANCLSTESTDTPKAPVITLPSEAREQMATLGERTFNCCYPGCHFKTVHGMKDLDRH 320
Query: 2406 AALNT-EKRFPCEFCGRAFSQGSEWERHVLRH 2436
++T +K CEFC + FS+ H+ H
Sbjct: 321 LRIHTGDKPHKCEFCDKCFSRKDNLTMHMRCH 352
Score = 50.8 bits (120), Expect = 2e-05
Identities = 68/304 (22%), Positives = 105/304 (34%), Gaps = 66/304 (21%)
Query: 1493 HPGMKVKAADFAQDID----INPG-AVYKCRHCPYINTRIHGVLTHYQKRHPSIKVTAED 1547
+PG K +D+D I+ G +KC C +R LT + + H S+K
Sbjct: 303 YPGCHFKTVHGMKDLDRHLRIHTGDKPHKCEFCDKCFSRKDN-LTMHMRCHTSVKPHK-- 359
Query: 1548 FVHDVEQSADISQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFDV 1607
H + +A + + +++ RI Y+C+LCPY +L +H + F
Sbjct: 360 -CHLCDYAA-VDSSSLKKHLRIHSDER-PYKCQLCPYASRNSSQLTVHLRSHTGDTPFQC 416
Query: 1608 FSQSPP-KLPVPLEPEMTTEVSPSQVSITEEEVGEEPVSTSHFSTSHLVSHTVFRCQLCK 1666
+ S K+ L+ M GE+P F+C+ C
Sbjct: 417 WLCSAKFKISSDLKRHMIVHS------------GEKP----------------FKCEFCD 448
Query: 1667 YFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCALCAYTNPIRKGLAAHYQKRHDIDAYY 1726
C+ + + H RIKH FKC CA+ R L H + H D +
Sbjct: 449 VRCTMKANLKSHIRIKHT------------FKCLHCAFQGRDRADLLEH-SRLHQAD-HP 494
Query: 1727 THCLAASRTISDKPNKVIIPSPPKDDSPQLSEELRRAVEKKKCSLCSFQSFSKKGIVSHY 1786
C S + S + D P KC CSF + + H
Sbjct: 495 EKCPECSYSCSSAAALRVHSRVHCKDRP------------FKCDFCSFDTKRPSSLAKHV 542
Query: 1787 MKRH 1790
K H
Sbjct: 543 DKVH 546
Score = 46.6 bits (109), Expect = 3e-04
Identities = 100/493 (20%), Positives = 178/493 (36%), Gaps = 94/493 (19%)
Query: 1243 KPASCVLVSPSNLERDKTK--------LRALKCRQCSYTSPYFYALRKHIKKDHPALKAT 1294
KP C + +DK K ++ KC+ C Y + +L KH++
Sbjct: 173 KPHKCEVCGKCFSRKDKLKTHMRCHTGVKPYKCKTCDYAAADSSSLNKHLRIHSD----- 227
Query: 1295 VTSIMRWAFLDGLIEAGYHCEWCIYSHTEPNGLLLHYQRRHPEHYVDYTYMATKL--WAG 1352
E + C+ C Y+ + L +H + D A L +
Sbjct: 228 --------------ERPFKCQICPYASRNSSQLTVHLRSHTASELDDDVPKANCLSTEST 273
Query: 1353 PDPSPPSLTMPAEA---------KTYRC--RDCVFEAV-SIWDITNHYQAFHPWAMNGDE 1400
P P +T+P+EA +T+ C C F+ V + D+ H + GD+
Sbjct: 274 DTPKAPVITLPSEAREQMATLGERTFNCCYPGCHFKTVHGMKDLDRHLRIH-----TGDK 328
Query: 1401 SVLLDIIKEKDAVEKPILSSEELAGPVNCENSIPTPFPEQEAECPEDA--RLSPEKSLQL 1458
+ + +K + L + C S+ P + C A S +K L++
Sbjct: 329 P------HKCEFCDKCFSRKDNLTMHMRCHTSVK---PHKCHLCDYAAVDSSSLKKHLRI 379
Query: 1459 ASANPAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPG----------MKVK-AADFAQDI 1507
S PY+C +C N L H + H G K K ++D + +
Sbjct: 380 HS-----DERPYKCQLCPYASRNSSQLTVHL-RSHTGDTPFQCWLCSAKFKISSDLKRHM 433
Query: 1508 DINPG-AVYKCRHCPYINTRIHGVLTHYQKRHPSIKVTAEDFVHDVEQSADISQNDVEET 1566
++ G +KC C T + +H + +H +H Q D + D+ E
Sbjct: 434 IVHSGEKPFKCEFCDVRCTMKANLKSHIRIKH------TFKCLHCAFQGRD--RADLLEH 485
Query: 1567 SRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFDV-FSQSPPKLPVPLEPEMTT 1625
SR+ + + +C C Y+ + L++H + F F K P L +
Sbjct: 486 SRLHQADH-PEKCPECSYSCSSAAALRVHSRVHCKDRPFKCDFCSFDTKRPSSLAKHVDK 544
Query: 1626 EVSPSQVSITEEEVGEEPV---STSHFSTSHLVSHTVFRCQLCKYFCSTRKGIARHYRIK 1682
+ +G+E + S+ H + +V+ FRC+ C R R ++ +
Sbjct: 545 VHRDEAKTENRAPLGKEGLREGSSQH--VAKIVTQRAFRCETCG-ASFVRDDSLRCHKKQ 601
Query: 1683 HNNVRAQPEGKNN 1695
H++ Q E KN+
Sbjct: 602 HSD---QSENKNS 611
Score = 42.7 bits (99), Expect = 0.004
Identities = 58/290 (20%), Positives = 102/290 (35%), Gaps = 47/290 (16%)
Query: 8 GCDFRAP-SYEDLKAHIQDVHTA-------FLQPTDVAEDNVN-ELRCGS------VNAS 52
GC F+ +DL H++ +HT F +DN+ +RC + +
Sbjct: 305 GCHFKTVHGMKDLDRHLR-IHTGDKPHKCEFCDKCFSRKDNLTMHMRCHTSVKPHKCHLC 363
Query: 53 NQTEVEFSSIKDEFAIAEDLSGQNATSLGTGGYYGHSPGYYGQHIAANPKPTNKFFQCKF 112
+ V+ SS+K I D + Y + H+ ++ T FQC
Sbjct: 364 DYAAVDSSSLKKHLRIHSD---ERPYKCQLCPYASRNSSQLTVHLRSHTGDTP--FQCWL 418
Query: 113 CVRYFRSKNLLIEHTRKVHGAQAEGSSSGPPVPGSLNYNIMMHEGFGKVFSCQFCTYKSP 172
C F+ + L H VH + V ++ N+ H F C C ++
Sbjct: 419 CSAKFKISSDLKRHMI-VHSGEKPFKCEFCDVRCTMKANLKSHIRIKHTFKCLHCAFQGR 477
Query: 173 RRARIIKHQKMYHKNNLKETTAPPPAPAPMPDPVVPPVSLQDPCKELPAEVVERSILESM 232
RA +++H +++ ++ ++ P V + CK+ P
Sbjct: 478 DRADLLEHSRLHQADHPEKC---PECSYSCSSAAALRVHSRVHCKDRP------------ 522
Query: 233 VKPLTKSRGNFCCEWCSYQTPRRERWCDHMMKKHRSMVKILSSLRQQQEG 282
F C++CS+ T R H+ K HR K + +EG
Sbjct: 523 ----------FKCDFCSFDTKRPSSLAKHVDKVHRDEAKTENRAPLGKEG 562
Score = 41.2 bits (95), Expect = 0.013
Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 3/79 (3%)
Query: 440 QCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTGTTSDW 499
+C C + + S+ +H+ IH + YKC CP+ ++S +L H + HTG T
Sbjct: 359 KCHLCDYAAVDSSSLKKHLR-IHSDERP--YKCQLCPYASRNSSQLTVHLRSHTGDTPFQ 415
Query: 500 DAVNSQSESISSSLNEGVV 518
+ S ISS L ++
Sbjct: 416 CWLCSAKFKISSDLKRHMI 434
Score = 38.1 bits (87), Expect = 0.11
Identities = 19/74 (25%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTGTTSD 498
++C C + S+++H+ IH + +KC CP+ ++S +L H + HT + D
Sbjct: 203 YKCKTCDYAAADSSSLNKHLR-IHSDERP--FKCQICPYASRNSSQLTVHLRSHTASELD 259
Query: 499 WDAVNSQSESISSS 512
D + S S+
Sbjct: 260 DDVPKANCLSTEST 273
Score = 35.8 bits (81), Expect = 0.54
Identities = 35/167 (20%), Positives = 64/167 (38%), Gaps = 19/167 (11%)
Query: 105 NKFFQCKFCVRYFRSKNLLIEHTRKVHGAQ---AEGSSSGPPVPGSLNYNIMMHEGFGKV 161
+K +C+ C + F K+ L H R G + + SLN ++ +H +
Sbjct: 172 DKPHKCEVCGKCFSRKDKLKTHMRCHTGVKPYKCKTCDYAAADSSSLNKHLRIHSD-ERP 230
Query: 162 FSCQFCTYKSPRRARIIKHQKMYHKNNLKETT--APPPAPAPMPDPVVPPVSLQDPCKEL 219
F CQ C Y S +++ H + + + L + A + P P ++L +E
Sbjct: 231 FKCQICPYASRNSSQLTVHLRSHTASELDDDVPKANCLSTESTDTPKAPVITLPSEAREQ 290
Query: 220 PAEVVERSILESMVKPLTKSRGNFCCEWCSYQTPRRERWCDHMMKKH 266
A + ER+ N C C ++T + D ++ H
Sbjct: 291 MATLGERTF-------------NCCYPGCHFKTVHGMKDLDRHLRIH 324
Score = 35.0 bits (79), Expect = 0.93
Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 12/78 (15%)
Query: 438 RFQC--PFCPFLTMH-RRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
R C P C F T + + + RH++ IH K +KC+ C KL H +CHTG
Sbjct: 143 RLNCCYPGCQFKTAYGMKDMERHLK-IHTGDKP--HKCEVCGKCFSRKDKLKTHMRCHTG 199
Query: 495 T------TSDWDAVNSQS 506
T D+ A +S S
Sbjct: 200 VKPYKCKTCDYAAADSSS 217
Score = 33.9 bits (76), Expect = 2.1
Identities = 17/59 (28%), Positives = 26/59 (44%), Gaps = 3/59 (5%)
Query: 434 RFMNRFQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCH 492
R + F+C C F R + H +H + KC EC ++C S+ L H + H
Sbjct: 462 RIKHTFKCLHCAFQGRDRADLLEH-SRLHQADHPE--KCPECSYSCSSAAALRVHSRVH 517
Score = 33.5 bits (75), Expect = 2.7
Identities = 27/123 (21%), Positives = 45/123 (36%), Gaps = 35/123 (28%)
Query: 843 YYCKHCDFNNKSARSVSTHYQRMHPYIKFSFRYILDPNDHSAVYRCLECYIDYTNFEDLQ 902
+ C+ CD ++ +H + H ++CL C + DL
Sbjct: 442 FKCEFCDVRCTMKANLKSHIRIKH------------------TFKCLHCAFQGRDRADLL 483
Query: 903 QHYGEH---HPE-------------AMNVLNFDH-SDLIYRCRFCSYTSPNVRSLMPHYQ 945
+H H HPE A+ V + H D ++C FCS+ + SL H
Sbjct: 484 EHSRLHQADHPEKCPECSYSCSSAAALRVHSRVHCKDRPFKCDFCSFDTKRPSSLAKHVD 543
Query: 946 RMH 948
++H
Sbjct: 544 KVH 546
Score = 32.7 bits (73), Expect = 4.6
Identities = 25/77 (32%), Positives = 34/77 (44%), Gaps = 12/77 (15%)
Query: 439 FQC--PFCPFLTMH-RRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTGT 495
F C P C F T+H + + RH+ IH K +KC+ C L H +CHT
Sbjct: 299 FNCCYPGCHFKTVHGMKDLDRHLR-IHTGDKP--HKCEFCDKCFSRKDNLTMHMRCHTSV 355
Query: 496 ------TSDWDAVNSQS 506
D+ AV+S S
Sbjct: 356 KPHKCHLCDYAAVDSSS 372
>gi|6005976 zinc finger protein 208 [Homo sapiens]
Length = 1167
Score = 111 bits (278), Expect = 8e-24
Identities = 141/613 (23%), Positives = 225/613 (36%), Gaps = 106/613 (17%)
Query: 1845 PFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQST 1904
P+RC +C K +FS +L H H +Y+C+ C +
Sbjct: 228 PYRCKECGK-AFSKFSILTKHKVIHTGE-----------------KSYKCEECGKAFNQS 269
Query: 1905 AELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVPKIKERK 1964
A LT H IH E + + E + SK A E+P
Sbjct: 270 AILTKHKIIHTGE---KPNKCEECGKAFSKVSTLTTHKAIHAGEKP-------------- 312
Query: 1965 VVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVP-------AVSAAVKGLRSHERSHLALA 2017
YKCK C + + + H K + G P + L H+ H
Sbjct: 313 ---YKCKECGKAFSKVSTLITH--KAIHAGEKPYKCKECGKAFSKFSILTKHKVIH---- 363
Query: 2018 MFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAH 2077
T E Y C+ C + L H + H G KP++C+ C S S L H + H
Sbjct: 364 --TGEKPYKCEECGKAYKWPSTLSYHKKIHTGE-KPYKCEECGKGFSMFSILTKHEV-IH 419
Query: 2078 AGEHAYKCSWCSFSTMTISQLKEHSLKVH-----------GKALTLPRPRIVSLLSSHSH 2126
GE YKC C + S L EH K+H GK + S LS H
Sbjct: 420 TGEKPYKCEECGKAFNWSSNLMEHK-KIHTGETPYKCEECGKGFSWS-----STLSYHKK 473
Query: 2127 -HSSQKATPAEEVEDSNDSS--YSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAAGT 2183
H+ +K EE + + S + + Y+ + S+VS + A
Sbjct: 474 IHTVEKPYKCEECGKAFNQSAILIKHKRIHTGEKPYKCEECGKTFSKVSTLTTHKAIHAG 533
Query: 2184 EQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGH 2243
E+ + C+ C + + ++ H + H G+K +KCK+C S T H
Sbjct: 534 EKPYK----CKECGKTFIKVSTLTTH-KAIHAGEKPYKCKECGKAFSKFSILTKH----- 583
Query: 2244 SAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRCD 2303
V G K +C C + N+++H +H E+ ++C+
Sbjct: 584 -KVIHTGEKPYKCEECGKAFNWSSNLMEHKRIHTGEKP------------------YKCE 624
Query: 2304 KCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFELVGRV 2363
+C + S+ L +H H KPYKC+ C K + L H + H V + ++
Sbjct: 625 ECGKSFSTFSVLTKHKVIHTGEKPYKCEECGKAYKWSSTLSYH-KKIHTVEKPYKCEECG 683
Query: 2364 NLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAF 2423
+ K + +D++ + E K + + + H A EK + C+ CG+AF
Sbjct: 684 KAFNRSAILIKHKRIHTDEKPYKCEECGKTFSK-VSTLTTHKAIHAGEKPYKCKECGKAF 742
Query: 2424 SQGSEWERHVLRH 2436
S+ S +H + H
Sbjct: 743 SKFSILTKHKVIH 755
Score = 111 bits (277), Expect = 1e-23
Identities = 236/1106 (21%), Positives = 376/1106 (33%), Gaps = 249/1106 (22%)
Query: 1367 KTYRCRDCVFEAVSIWDITNHYQAFHPWAMNG---------DESVLLDIIKEKDAVEKPI 1417
K YRC++C +A S + I ++ H + ++S +L K EKP
Sbjct: 227 KPYRCKECG-KAFSKFSILTKHKVIHTGEKSYKCEECGKAFNQSAILTKHKIIHTGEKPN 285
Query: 1418 LSSEELAGPVNCENSIPTPFP----EQEAECPEDARLSPEKSLQLASANPAISSTPYQCT 1473
EE + +++ T E+ +C E + + S + PY+C
Sbjct: 286 -KCEECGKAFSKVSTLTTHKAIHAGEKPYKCKECGKAFSKVSTLITHKAIHAGEKPYKCK 344
Query: 1474 VCQSEYNNLHGLLTHYGKKHPGMKVKAADFAQDIDINPGAVYKCRHCPYINTRIHGVLTH 1533
C ++ +LT + H G K YKC C + L++
Sbjct: 345 ECGKAFSKF-SILTKHKVIHTGEKP----------------YKCEECGKAY-KWPSTLSY 386
Query: 1534 YQKRHPSIKVTAEDFVHDVEQSADISQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLK 1593
++K H T E E S + + G Y+C+ C L
Sbjct: 387 HKKIH-----TGEKPYKCEECGKGFSMFSILTKHEVIHTGEKPYKCEECGKAFNWSSNLM 441
Query: 1594 IHYEKYHNQPEFDVFSQSPPKLPVPLEPEMTTEVSPSQVSITEEEVGEEPVSTSHFSTSH 1653
H +K H ++P K EE G+ S S + H
Sbjct: 442 EH-KKIHT-------GETPYKC---------------------EECGKG-FSWSSTLSYH 471
Query: 1654 LVSHTV---FRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCALCAYTNPIRK 1710
HTV ++C+ C + + +H RI H + +KC C T
Sbjct: 472 KKIHTVEKPYKCEECGKAFNQSAILIKHKRI-HTGEKP--------YKCEECGKTFSKVS 522
Query: 1711 GLAAHYQKRHDIDAYYTHCLAASRTISDKPNKVIIPSPPKDDSPQLSEELRRAVEKKKCS 1770
L H Y C +T K + + + + KC
Sbjct: 523 TLTTHKAIHAGEKPY--KCKECGKTFI------------KVSTLTTHKAIHAGEKPYKCK 568
Query: 1771 LCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGYFTAVYADEHEKPTLMEEEERGNFE 1830
C ++FSK I++ + H G P K + G F + LME + E
Sbjct: 569 ECG-KAFSKFSILTKHKVIHTGEKPYK--CEECGKAF-------NWSSNLMEHKRIHTGE 618
Query: 1831 KAEVEGEAQEIEWLPFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQNS 1890
K P++C +C K SFST +L H H G P
Sbjct: 619 K-------------PYKCEECGK-SFSTFSVLTKHKVIH-----------TGEKP----- 648
Query: 1891 TYQCKHCDSKLQSTAELTSHLNIHNEEFQKRAK---RQERRKQLLSKQKYADGAFADFKQ 1947
Y+C+ C + ++ L+ H IH E + + + R +L K K +K
Sbjct: 649 -YKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKAFNRSAILIKHKRIHTDEKPYKC 707
Query: 1948 ERPFGHLEEVPKIKERKVVG-----YKCKFCVEVHPTLRAICNHLRKHVQYGNVP----A 1998
E +V + K + YKCK C + + H K + G P
Sbjct: 708 EECGKTFSKVSTLTTHKAIHAGEKPYKCKECGKAFSKFSILTKH--KVIHTGEKPYKCEE 765
Query: 1999 VSAAVKG---LRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFR 2055
A K L H++ H T E Y C+ C + L +H H G KP++
Sbjct: 766 CGKAYKWPSTLSYHKKIH------TGEKPYKCEECGKGFSMFSILTKHEVIHTGE-KPYK 818
Query: 2056 CKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVHGKALTLPRP 2115
C+ C S+ S H K HAGE YKC C GKA
Sbjct: 819 CEECGKAFSWLSVFSKH-KKTHAGEKFYKCEAC------------------GKAYNT--- 856
Query: 2116 RIVSLLSSHSH-HSSQKATPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNSRVSPV 2174
S+L+ H H+ +K EE + + + S +
Sbjct: 857 --FSILTKHKVIHTGEKPYKCEECGKAFN---------------WSSNLMEHKKIHTGET 899
Query: 2175 PLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSA 2234
P CE C+ + + S+ H + H G+K +KC++C + S
Sbjct: 900 PYK---------------CEECDKAFSWPSSLTEH-KATHAGEKPYKCEECGKAFSWPSR 943
Query: 2235 FTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKY 2294
T H +A H+ G + +C C + N+++H +H E+
Sbjct: 944 LTEH-KATHA-----GEEPYKCEECGKAFNWSSNLMEHKRIHTGEKP------------- 984
Query: 2295 LQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVS 2354
++C++C + S+ L +H H KPYKC+ C K + L H + H V
Sbjct: 985 -----YKCEECGKSFSTFSILTKHKVIHTGEKPYKCEECGKAYKWSSTLSYH-KKIHTVE 1038
Query: 2355 RNFELV----GRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNT 2410
+ ++ G V L + K + + K EE + +R+ H
Sbjct: 1039 KPYKCEECGKGFVMFSILAKHKV---IHTGEKLYKCEECGKAYKWPSTLRY--HKKIHTG 1093
Query: 2411 EKRFPCEFCGRAFSQGSEWERHVLRH 2436
EK + CE CG+AFS S +H + H
Sbjct: 1094 EKPYKCEECGKAFSTFSILTKHKVIH 1119
Score = 85.1 bits (209), Expect = 8e-16
Identities = 110/493 (22%), Positives = 181/493 (36%), Gaps = 67/493 (13%)
Query: 1988 RKHVQYGNVPAVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTH 2047
+KH+Q + L H+R ++TRE+ Y C+ + L + H
Sbjct: 170 KKHLQCKEYVRSFCMLSHLSQHKR------IYTRENSYKCEEGGKAFNWSSTLTYYKSAH 223
Query: 2048 HGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVH- 2106
G KP+RCK C S S L H + H GE +YKC C + + L +H + +H
Sbjct: 224 TGE-KPYRCKECGKAFSKFSILTKHKV-IHTGEKSYKCEECGKAFNQSAILTKHKI-IHT 280
Query: 2107 ----------GKALTLPRPRIVSLLSSHSHHSSQKATPAEEVED--SNDSSYSEPPDVQQ 2154
GKA + ++ +L + + H+ +K +E S S+ +
Sbjct: 281 GEKPNKCEECGKAFS----KVSTLTTHKAIHAGEKPYKCKECGKAFSKVSTLITHKAIHA 336
Query: 2155 QLNHYQSAALARNNSRVSPVPLSGAAAGTEQKT----EAVLHCEFCEFSSGYIQSIRRHY 2210
Y+ + S+ S + T+ K E CE C + + ++ H
Sbjct: 337 GEKPYKCKECGKAFSKFSIL--------TKHKVIHTGEKPYKCEECGKAYKWPSTLSYH- 387
Query: 2211 RDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMI 2270
+ H G+K +KC++C S T H V G K +C C + N++
Sbjct: 388 KKIHTGEKPYKCEECGKGFSMFSILTKH------EVIHTGEKPYKCEECGKAFNWSSNLM 441
Query: 2271 DHIVLHREERVVPIEVCRSKLS--------KYLQGV--VFRCDKCTFTCSSDESLQQHIE 2320
+H +H E E C S K + V ++C++C + L +H
Sbjct: 442 EHKKIHTGETPYKCEECGKGFSWSSTLSYHKKIHTVEKPYKCEECGKAFNQSAILIKHKR 501
Query: 2321 KHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFELVGRVNLDQLEQMKEKMESSSS 2380
H KPYKC+ C L + HK E + +K ++
Sbjct: 502 IHTGEKPYKCEECGKTFSKVSTLTT-----HKAIHAGEKPYKCKECGKTFIKVSTLTTHK 556
Query: 2381 DDEDKEEEMNSKAEDRELMRFS---DHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRHG 2437
E+ K + +FS H EK + CE CG+AF+ W +++ H
Sbjct: 557 AIHAGEKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGKAFN----WSSNLMEHK 612
Query: 2438 MALNDTKQVSREE 2450
K EE
Sbjct: 613 RIHTGEKPYKCEE 625
Score = 59.7 bits (143), Expect = 4e-08
Identities = 82/354 (23%), Positives = 127/354 (35%), Gaps = 39/354 (11%)
Query: 1768 KCSLCSFQSFSKKGIVSHYMKRHPGV-FPKKQHASKLGGYFTAVYADE----HEKPTLME 1822
KC C ++FS + S + K H G F K + K F+ + + EKP E
Sbjct: 818 KCEECG-KAFSWLSVFSKHKKTHAGEKFYKCEACGKAYNTFSILTKHKVIHTGEKPYKCE 876
Query: 1823 EEERG-NFEKAEVEGEAQEIEWLPFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIIL 1881
E + N+ +E + P++C +C K +FS L H H
Sbjct: 877 ECGKAFNWSSNLMEHKKIHTGETPYKCEECDK-AFSWPSSLTEHKATH-----------A 924
Query: 1882 GNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHNEE----FQKRAKRQERRKQLLSKQKY 1937
G P Y+C+ C + LT H H E ++ K L+ ++
Sbjct: 925 GEKP------YKCEECGKAFSWPSRLTEHKATHAGEEPYKCEECGKAFNWSSNLMEHKRI 978
Query: 1938 ADGAFADFKQERPFGHLEEVPKIKERKVVG-----YKCKFCVEVHPTLRAICNHLRKHVQ 1992
G +K E + + KV+ YKC+ C + + + H + H
Sbjct: 979 HTGE-KPYKCEECGKSFSTFSILTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTV 1037
Query: 1993 YGNVPAVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHK 2052
KG + T E Y C+ C + L H + H G K
Sbjct: 1038 EKPYKCEECG-KGFVMFSILAKHKVIHTGEKLYKCEECGKAYKWPSTLRYHKKIHTGE-K 1095
Query: 2053 PFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVH 2106
P++C+ C S S L H + H GE YKC C + +S +H K+H
Sbjct: 1096 PYKCEECGKAFSTFSILTKHKV-IHTGEKPYKCEECGKAFSWLSVFSKHK-KIH 1147
Score = 49.3 bits (116), Expect = 5e-05
Identities = 163/820 (19%), Positives = 260/820 (31%), Gaps = 172/820 (20%)
Query: 1308 IEAGYHCEWCIYSHTEPNGLLLHYQRRHPEHYVDYTYMATKLWAGPDPSPPSLTMPAEAK 1367
+E Y CE C + + + +L+ ++R H K ++ + A K
Sbjct: 477 VEKPYKCEECGKAFNQ-SAILIKHKRIHTGEKPYKCEECGKTFSKVSTLTTHKAIHAGEK 535
Query: 1368 TYRCRDCVFEAVSIWDITNHYQAFHPWAMNGDESVLLDIIKEKDAVEKPILSSEELAGPV 1427
Y+C++C + + +T H +A H A EKP E G
Sbjct: 536 PYKCKECGKTFIKVSTLTTH-KAIH-------------------AGEKPYKCKE--CGKA 573
Query: 1428 NCENSIPTPFP-----EQEAECPEDARLSPEKSLQLASANPAISSTPYQCTVCQSEYNNL 1482
+ SI T E+ +C E + S + PY+C C ++
Sbjct: 574 FSKFSILTKHKVIHTGEKPYKCEECGKAFNWSSNLMEHKRIHTGEKPYKCEECGKSFSTF 633
Query: 1483 HGLLTHYGKKHPGMKV-------KAADFAQDIDINPGA-----VYKCRHCPYINTRIHGV 1530
+LT + H G K KA ++ + + YKC C R +
Sbjct: 634 -SVLTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKAFNR-SAI 691
Query: 1531 LTHYQKRHPSIKVTAEDFVHDVEQSADISQNDVEETSRIFKQGYGAYRCKLCPYTHGTLE 1590
L +++ H T E E S+ T + G Y+CK C
Sbjct: 692 LIKHKRIH-----TDEKPYKCEECGKTFSKVSTLTTHKAIHAGEKPYKCKECGKAFSKFS 746
Query: 1591 KLKIHYEKYHNQPEFDVFSQSPPKLPVPLEPEMTTEVSPSQVSITEEEVGEEPVSTSHFS 1650
L H + + + + P ++ + EE G+ S
Sbjct: 747 ILTKHKVIHTGEKPYKC-EECGKAYKWPSTLSYHKKIHTGEKPYKCEECGKG-FSMFSIL 804
Query: 1651 TSHLVSHT---VFRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCALCAYTNP 1707
T H V HT ++C+ C S ++H + +KC C
Sbjct: 805 TKHEVIHTGEKPYKCEECGKAFSWLSVFSKHKKT---------HAGEKFYKCEACG---- 851
Query: 1708 IRKGLAAHYQKRHDIDAYYTHCLAASRTI---SDKPNKVIIPSPPKDDSPQLSE--ELRR 1762
AY T + + +KP K + S L E ++
Sbjct: 852 ---------------KAYNTFSILTKHKVIHTGEKPYKCEECGKAFNWSSNLMEHKKIHT 896
Query: 1763 AVEKKKCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGYFT-AVYADEHEKPTLM 1821
KC C ++FS ++ + H G P K + G F+ EH+
Sbjct: 897 GETPYKCEECD-KAFSWPSSLTEHKATHAGEKPYK--CEECGKAFSWPSRLTEHKATHAG 953
Query: 1822 EE----EERG---NFEKAEVEGEAQEIEWLPFRCIKCFKLSFSTAELLCMHYTDHHSRDL 1874
EE EE G N+ +E + P++C +C K SFST +L H H
Sbjct: 954 EEPYKCEECGKAFNWSSNLMEHKRIHTGEKPYKCEECGK-SFSTFSILTKHKVIH----- 1007
Query: 1875 KRDFIILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHNEEFQKRAKRQERRK----- 1929
G P Y+C+ C + ++ L+ H IH E K K +E K
Sbjct: 1008 ------TGEKP------YKCEECGKAYKWSSTLSYHKKIHTVE--KPYKCEECGKGFVMF 1053
Query: 1930 QLLSKQKYADGAFADFKQERPFGHLEEVPKIKERKVVG-----YKCKFCVEVHPTLRAIC 1984
+L+K K +K E + ++ K + YKC+ C + T +
Sbjct: 1054 SILAKHKVIHTGEKLYKCEECGKAYKWPSTLRYHKKIHTGEKPYKCEECGKAFSTFSILT 1113
Query: 1985 NHLRKHVQYGNVPAVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHM 2044
H H T E Y C+ C ++ +H
Sbjct: 1114 KHKVIH-----------------------------TGEKPYKCEECGKAFSWLSVFSKHK 1144
Query: 2045 QTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYK 2084
+ H G P TH K HAGE YK
Sbjct: 1145 KIHTGVPNP----------------PTH-KKIHAGEKLYK 1167
>gi|239757222 PREDICTED: zinc finger protein 726 [Homo sapiens]
Length = 853
Score = 109 bits (273), Expect = 3e-23
Identities = 147/650 (22%), Positives = 227/650 (34%), Gaps = 137/650 (21%)
Query: 1845 PFRCIKCFKLSFSTAELLCM--HYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQ 1902
PF+C C K SF CM H T H S +Y+CK C
Sbjct: 287 PFKCKNCVK-SF------CMFSHKTQHKSI-------------YTTEKSYKCKECGKTFN 326
Query: 1903 STAELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVPKIKE 1962
++ LT+H H EE K K +E K Y H E P
Sbjct: 327 WSSTLTNHKKTHTEE--KPYKCEEYGKAFNQSSNYTTHKVT---------HTGEKP---- 371
Query: 1963 RKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVPA-------VSAAVKGLRSHERSHLA 2015
YKC+ C + + H R H G P + L H+R H+
Sbjct: 372 -----YKCEECGKAFSQSSTLTIHKRIHT--GEKPCKCEECGKAFSQPSALTIHKRMHIG 424
Query: 2016 LAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILK 2075
E Y C+ C + L RH + H G KP++C+ C+ S L TH +
Sbjct: 425 ------EKPYKCEECGKAFVWSSTLTRHKRLHSGE-KPYKCEECAKAFSQFGHLTTHRI- 476
Query: 2076 AHAGEHAYKCSWCSFSTMTISQLKEHSLKVH-----------GKALTLPRPRIVSLLSSH 2124
H GE YKC C + + S L +H ++H GKA R +L
Sbjct: 477 IHTGEKPYKCEECGKAFIWPSTLTKHK-RIHTGEKPYKCEECGKAFH----RSSNLTKHK 531
Query: 2125 SHHSSQKATPAEEVEDSN--DSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAAG 2182
H+ +K EE + S+ +E + + Y+ ++ SR S +
Sbjct: 532 IIHTGEKPYKCEECGKAFIWSSNLTEHKKIHTREKPYKCEECSKAFSRSSALTTHKRMHT 591
Query: 2183 TEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAG 2242
E+ + CE C + ++ H + H G+K +KC++C S + H
Sbjct: 592 GEKPYK----CEECGKAFSQSSTLTAH-KIIHTGEKPYKCEECGKAFILSSTLSKHKRI- 645
Query: 2243 HSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSK--------- 2293
G K +C C N+ H ++H E+ E C ++
Sbjct: 646 -----HTGEKPYKCEECGKTFNQSSNLSTHKIIHTGEKPYKCEECGKAFNRSSNLSTHKI 700
Query: 2294 -YLQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHK 2352
+ ++CD+C + +L +H H KPYKC+ C H++ L H+R HK
Sbjct: 701 IHTGEKPYKCDECGKSFIWSSTLFKHXIIHTGEKPYKCEECGKAFNHSQIL-LHIR--HK 757
Query: 2353 VSRNFELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEK 2412
+M + ++ K ++S F H K
Sbjct: 758 -----------------RMHTGEKPYKCEECGKSFNLSS--------TFIKHKVIHTGVK 792
Query: 2413 RFPCEFCGRAFSQGSEWERHVLRH-----------GMALNDTKQVSREEI 2451
+ CE CG+ F S RH H G A N + ++ ++I
Sbjct: 793 LYKCEECGKVFFWSSALTRHKKIHAGQQPYKWEKIGKAFNQSSHLTTDKI 842
Score = 82.0 bits (201), Expect = 7e-15
Identities = 98/447 (21%), Positives = 161/447 (36%), Gaps = 54/447 (12%)
Query: 2039 NLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQL 2098
NL+R+ + H KPF+CK C KS KT + E +YKC C + S L
Sbjct: 274 NLNRY-KIRHTRKKPFKCKNC-VKSFCMFSHKTQHKSIYTTEKSYKCKECGKTFNWSSTL 331
Query: 2099 KEHSLKVHGKALTLPRPRIVSLLSSHSHHSSQKAT-----PAEEVEDSNDSSYSEPPDVQ 2153
H K H + + S++++ K T P + E S S +
Sbjct: 332 TNHK-KTHTEEKPYKCEEYGKAFNQSSNYTTHKVTHTGEKPYKCEECGKAFSQSSTLTIH 390
Query: 2154 QQLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDK 2213
++++ + + P + E CE C + + ++ RH R
Sbjct: 391 KRIHTGEKPCKCEECGKAFSQPSALTIHKRMHIGEKPYKCEECGKAFVWSSTLTRHKR-L 449
Query: 2214 HGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHI 2273
H G+K +KC++C+ AF+ + G K +C C + + H
Sbjct: 450 HSGEKPYKCEECA------KAFSQFGHLTTHRIIHTGEKPYKCEECGKAFIWPSTLTKHK 503
Query: 2274 VLHREERVVPIEVC------RSKLSK----YLQGVVFRCDKCTFTCSSDESLQQHIEKHN 2323
+H E+ E C S L+K + ++C++C +L +H + H
Sbjct: 504 RIHTGEKPYKCEECGKAFHRSSNLTKHKIIHTGEKPYKCEECGKAFIWSSNLTEHKKIHT 563
Query: 2324 ELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFELVGRVNLDQLEQMKEKMESSSSDDE 2383
KPYKC+ C + L +H R H + + + E+ + SS+
Sbjct: 564 REKPYKCEECSKAFSRSSALTTHKR-MHTGEKPY---------KCEECGKAFSQSSTLTA 613
Query: 2384 DKEEEMNSKAEDRE--------LMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLR 2435
K K E S H EK + CE CG+ F+Q S H +
Sbjct: 614 HKIIHTGEKPYKCEECGKAFILSSTLSKHKRIHTGEKPYKCEECGKTFNQSSNLSTHKII 673
Query: 2436 H-----------GMALNDTKQVSREEI 2451
H G A N + +S +I
Sbjct: 674 HTGEKPYKCEECGKAFNRSSNLSTHKI 700
Score = 53.1 bits (126), Expect = 3e-06
Identities = 128/608 (21%), Positives = 214/608 (35%), Gaps = 108/608 (17%)
Query: 1515 YKCRHCPYINTRIHGVLTHYQKRHPSIK-VTAEDFVHDVEQSADISQNDVEETSRIFKQG 1573
YKC+ C LT+++K H K E++ QS++ + + V T G
Sbjct: 316 YKCKECGK-TFNWSSTLTNHKKTHTEEKPYKCEEYGKAFNQSSNYTTHKVTHT------G 368
Query: 1574 YGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFDVFSQSPPKLPVPLEPEMTTEVSPSQVS 1633
Y+C+ C L IH ++ H + P E PS ++
Sbjct: 369 EKPYKCEECGKAFSQSSTLTIH-KRIHTGEK-----------PCKCEECGKAFSQPSALT 416
Query: 1634 ITEE-EVGEEPVSTSHFSTSHLVSHTV------------FRCQLCKYFCSTRKGIARHYR 1680
I + +GE+P + + S T+ ++C+ C S + H R
Sbjct: 417 IHKRMHIGEKPYKCEECGKAFVWSSTLTRHKRLHSGEKPYKCEECAKAFSQFGHLTTH-R 475
Query: 1681 IKHNNVRAQPEGKNNLFKCALCAYTNPIRKGLAAHYQKRHDIDAYYT--HCLAASRTISD 1738
I H + +KC C L H ++ H + Y C A S+
Sbjct: 476 IIHTGEKP--------YKCEECGKAFIWPSTLTKH-KRIHTGEKPYKCEECGKAFHRSSN 526
Query: 1739 KPNKVIIPSPPKDD-----------SPQLSEELRRAVEKK--KCSLCSFQSFSKKGIVSH 1785
II + K S L+E + +K KC CS ++FS+ ++
Sbjct: 527 LTKHKIIHTGEKPYKCEECGKAFIWSSNLTEHKKIHTREKPYKCEECS-KAFSRSSALTT 585
Query: 1786 YMKRHPGVFPKK-QHASKLGGYFTAVYADE----HEKPTLMEEEERGNFEKAEVEGEAQE 1840
+ + H G P K + K + + A + EKP EE + F + + +
Sbjct: 586 HKRMHTGEKPYKCEECGKAFSQSSTLTAHKIIHTGEKPYKCEECGKA-FILSSTLSKHKR 644
Query: 1841 IEW--LPFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCD 1898
I P++C +C K +F+ + L H H G P Y+C+ C
Sbjct: 645 IHTGEKPYKCEECGK-TFNQSSNLSTHKIIH-----------TGEKP------YKCEECG 686
Query: 1899 SKLQSTAELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVP 1958
++ L++H IH E K K E K + ++ + H E P
Sbjct: 687 KAFNRSSNLSTHKIIHTGE--KPYKCDECGKSFI---------WSSTLFKHXIIHTGEKP 735
Query: 1959 KIKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVP-AVSAAVKGLRSHERSHLALA 2017
YKC+ C + + + + K + G P K
Sbjct: 736 ---------YKCEECGKAFNHSQILLHIRHKRMHTGEKPYKCEECGKSFNLSSTFIKHKV 786
Query: 2018 MFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAH 2077
+ T Y C+ C V + L RH + H G +P++ + + +S L T + H
Sbjct: 787 IHTGVKLYKCEECGKVFFWSSALTRHKKIHAG-QQPYKWEKIGKAFNQSSHLTTDKI-TH 844
Query: 2078 AGEHAYKC 2085
GE +YKC
Sbjct: 845 IGEKSYKC 852
Score = 37.4 bits (85), Expect = 0.19
Identities = 37/148 (25%), Positives = 54/148 (36%), Gaps = 16/148 (10%)
Query: 2296 QGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSR 2355
QG +C K +L ++ +H KP+KC+ C + S HK
Sbjct: 256 QGKASQCGKYLKVFYKFINLNRYKIRHTRKKPFKCKNC---------VKSFCMFSHKTQH 306
Query: 2356 NFELVGRVNLDQLEQMKEKMESSSSDDEDK--EEEMNSKAED-----RELMRFSDHGAAL 2408
+ E K SS+ + K EE K E+ + ++ H
Sbjct: 307 KSIYTTEKSYKCKECGKTFNWSSTLTNHKKTHTEEKPYKCEEYGKAFNQSSNYTTHKVTH 366
Query: 2409 NTEKRFPCEFCGRAFSQGSEWERHVLRH 2436
EK + CE CG+AFSQ S H H
Sbjct: 367 TGEKPYKCEECGKAFSQSSTLTIHKRIH 394
Score = 35.8 bits (81), Expect = 0.54
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C + ++S+H + IH K YKC+EC T S L HK HTG
Sbjct: 624 YKCEECGKAFILSSTLSKH-KRIHTGEKP--YKCEECGKTFNQSSNLSTHKIIHTG 676
Score = 32.3 bits (72), Expect = 6.0
Identities = 18/56 (32%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C + +++ H + IH K YKC+EC S L HK+ HTG
Sbjct: 540 YKCEECGKAFIWSSNLTEH-KKIHTREKP--YKCEECSKAFSRSSALTTHKRMHTG 592
>gi|239751727 PREDICTED: zinc finger protein 726 [Homo sapiens]
Length = 877
Score = 109 bits (273), Expect = 3e-23
Identities = 147/650 (22%), Positives = 227/650 (34%), Gaps = 137/650 (21%)
Query: 1845 PFRCIKCFKLSFSTAELLCM--HYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQ 1902
PF+C C K SF CM H T H S +Y+CK C
Sbjct: 311 PFKCKNCVK-SF------CMFSHKTQHKSI-------------YTTEKSYKCKECGKTFN 350
Query: 1903 STAELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVPKIKE 1962
++ LT+H H EE K K +E K Y H E P
Sbjct: 351 WSSTLTNHKKTHTEE--KPYKCEEYGKAFNQSSNYTTHKVT---------HTGEKP---- 395
Query: 1963 RKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVPA-------VSAAVKGLRSHERSHLA 2015
YKC+ C + + H R H G P + L H+R H+
Sbjct: 396 -----YKCEECGKAFSQSSTLTIHKRIHT--GEKPCKCEECGKAFSQPSALTIHKRMHIG 448
Query: 2016 LAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILK 2075
E Y C+ C + L RH + H G KP++C+ C+ S L TH +
Sbjct: 449 ------EKPYKCEECGKAFVWSSTLTRHKRLHSGE-KPYKCEECAKAFSQFGHLTTHRI- 500
Query: 2076 AHAGEHAYKCSWCSFSTMTISQLKEHSLKVH-----------GKALTLPRPRIVSLLSSH 2124
H GE YKC C + + S L +H ++H GKA R +L
Sbjct: 501 IHTGEKPYKCEECGKAFIWPSTLTKHK-RIHTGEKPYKCEECGKAFH----RSSNLTKHK 555
Query: 2125 SHHSSQKATPAEEVEDSN--DSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAAG 2182
H+ +K EE + S+ +E + + Y+ ++ SR S +
Sbjct: 556 IIHTGEKPYKCEECGKAFIWSSNLTEHKKIHTREKPYKCEECSKAFSRSSALTTHKRMHT 615
Query: 2183 TEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAG 2242
E+ + CE C + ++ H + H G+K +KC++C S + H
Sbjct: 616 GEKPYK----CEECGKAFSQSSTLTAH-KIIHTGEKPYKCEECGKAFILSSTLSKHKRI- 669
Query: 2243 HSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSK--------- 2293
G K +C C N+ H ++H E+ E C ++
Sbjct: 670 -----HTGEKPYKCEECGKTFNQSSNLSTHKIIHTGEKPYKCEECGKAFNRSSNLSTHKI 724
Query: 2294 -YLQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHK 2352
+ ++CD+C + +L +H H KPYKC+ C H++ L H+R HK
Sbjct: 725 IHTGEKPYKCDECGKSFIWSSTLFKHXIIHTGEKPYKCEECGKAFNHSQIL-LHIR--HK 781
Query: 2353 VSRNFELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEK 2412
+M + ++ K ++S F H K
Sbjct: 782 -----------------RMHTGEKPYKCEECGKSFNLSS--------TFIKHKVIHTGVK 816
Query: 2413 RFPCEFCGRAFSQGSEWERHVLRH-----------GMALNDTKQVSREEI 2451
+ CE CG+ F S RH H G A N + ++ ++I
Sbjct: 817 LYKCEECGKVFFWSSALTRHKKIHAGQQPYKWEKIGKAFNQSSHLTTDKI 866
Score = 82.0 bits (201), Expect = 7e-15
Identities = 98/447 (21%), Positives = 161/447 (36%), Gaps = 54/447 (12%)
Query: 2039 NLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQL 2098
NL+R+ + H KPF+CK C KS KT + E +YKC C + S L
Sbjct: 298 NLNRY-KIRHTRKKPFKCKNC-VKSFCMFSHKTQHKSIYTTEKSYKCKECGKTFNWSSTL 355
Query: 2099 KEHSLKVHGKALTLPRPRIVSLLSSHSHHSSQKAT-----PAEEVEDSNDSSYSEPPDVQ 2153
H K H + + S++++ K T P + E S S +
Sbjct: 356 TNHK-KTHTEEKPYKCEEYGKAFNQSSNYTTHKVTHTGEKPYKCEECGKAFSQSSTLTIH 414
Query: 2154 QQLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDK 2213
++++ + + P + E CE C + + ++ RH R
Sbjct: 415 KRIHTGEKPCKCEECGKAFSQPSALTIHKRMHIGEKPYKCEECGKAFVWSSTLTRHKR-L 473
Query: 2214 HGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHI 2273
H G+K +KC++C+ AF+ + G K +C C + + H
Sbjct: 474 HSGEKPYKCEECA------KAFSQFGHLTTHRIIHTGEKPYKCEECGKAFIWPSTLTKHK 527
Query: 2274 VLHREERVVPIEVC------RSKLSK----YLQGVVFRCDKCTFTCSSDESLQQHIEKHN 2323
+H E+ E C S L+K + ++C++C +L +H + H
Sbjct: 528 RIHTGEKPYKCEECGKAFHRSSNLTKHKIIHTGEKPYKCEECGKAFIWSSNLTEHKKIHT 587
Query: 2324 ELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFELVGRVNLDQLEQMKEKMESSSSDDE 2383
KPYKC+ C + L +H R H + + + E+ + SS+
Sbjct: 588 REKPYKCEECSKAFSRSSALTTHKR-MHTGEKPY---------KCEECGKAFSQSSTLTA 637
Query: 2384 DKEEEMNSKAEDRE--------LMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLR 2435
K K E S H EK + CE CG+ F+Q S H +
Sbjct: 638 HKIIHTGEKPYKCEECGKAFILSSTLSKHKRIHTGEKPYKCEECGKTFNQSSNLSTHKII 697
Query: 2436 H-----------GMALNDTKQVSREEI 2451
H G A N + +S +I
Sbjct: 698 HTGEKPYKCEECGKAFNRSSNLSTHKI 724
Score = 53.1 bits (126), Expect = 3e-06
Identities = 128/608 (21%), Positives = 214/608 (35%), Gaps = 108/608 (17%)
Query: 1515 YKCRHCPYINTRIHGVLTHYQKRHPSIK-VTAEDFVHDVEQSADISQNDVEETSRIFKQG 1573
YKC+ C LT+++K H K E++ QS++ + + V T G
Sbjct: 340 YKCKECGK-TFNWSSTLTNHKKTHTEEKPYKCEEYGKAFNQSSNYTTHKVTHT------G 392
Query: 1574 YGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFDVFSQSPPKLPVPLEPEMTTEVSPSQVS 1633
Y+C+ C L IH ++ H + P E PS ++
Sbjct: 393 EKPYKCEECGKAFSQSSTLTIH-KRIHTGEK-----------PCKCEECGKAFSQPSALT 440
Query: 1634 ITEE-EVGEEPVSTSHFSTSHLVSHTV------------FRCQLCKYFCSTRKGIARHYR 1680
I + +GE+P + + S T+ ++C+ C S + H R
Sbjct: 441 IHKRMHIGEKPYKCEECGKAFVWSSTLTRHKRLHSGEKPYKCEECAKAFSQFGHLTTH-R 499
Query: 1681 IKHNNVRAQPEGKNNLFKCALCAYTNPIRKGLAAHYQKRHDIDAYYT--HCLAASRTISD 1738
I H + +KC C L H ++ H + Y C A S+
Sbjct: 500 IIHTGEKP--------YKCEECGKAFIWPSTLTKH-KRIHTGEKPYKCEECGKAFHRSSN 550
Query: 1739 KPNKVIIPSPPKDD-----------SPQLSEELRRAVEKK--KCSLCSFQSFSKKGIVSH 1785
II + K S L+E + +K KC CS ++FS+ ++
Sbjct: 551 LTKHKIIHTGEKPYKCEECGKAFIWSSNLTEHKKIHTREKPYKCEECS-KAFSRSSALTT 609
Query: 1786 YMKRHPGVFPKK-QHASKLGGYFTAVYADE----HEKPTLMEEEERGNFEKAEVEGEAQE 1840
+ + H G P K + K + + A + EKP EE + F + + +
Sbjct: 610 HKRMHTGEKPYKCEECGKAFSQSSTLTAHKIIHTGEKPYKCEECGKA-FILSSTLSKHKR 668
Query: 1841 IEW--LPFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCD 1898
I P++C +C K +F+ + L H H G P Y+C+ C
Sbjct: 669 IHTGEKPYKCEECGK-TFNQSSNLSTHKIIH-----------TGEKP------YKCEECG 710
Query: 1899 SKLQSTAELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVP 1958
++ L++H IH E K K E K + ++ + H E P
Sbjct: 711 KAFNRSSNLSTHKIIHTGE--KPYKCDECGKSFI---------WSSTLFKHXIIHTGEKP 759
Query: 1959 KIKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVP-AVSAAVKGLRSHERSHLALA 2017
YKC+ C + + + + K + G P K
Sbjct: 760 ---------YKCEECGKAFNHSQILLHIRHKRMHTGEKPYKCEECGKSFNLSSTFIKHKV 810
Query: 2018 MFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAH 2077
+ T Y C+ C V + L RH + H G +P++ + + +S L T + H
Sbjct: 811 IHTGVKLYKCEECGKVFFWSSALTRHKKIHAG-QQPYKWEKIGKAFNQSSHLTTDKI-TH 868
Query: 2078 AGEHAYKC 2085
GE +YKC
Sbjct: 869 IGEKSYKC 876
Score = 37.4 bits (85), Expect = 0.19
Identities = 37/148 (25%), Positives = 54/148 (36%), Gaps = 16/148 (10%)
Query: 2296 QGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSR 2355
QG +C K +L ++ +H KP+KC+ C + S HK
Sbjct: 280 QGKASQCGKYLKVFYKFINLNRYKIRHTRKKPFKCKNC---------VKSFCMFSHKTQH 330
Query: 2356 NFELVGRVNLDQLEQMKEKMESSSSDDEDK--EEEMNSKAED-----RELMRFSDHGAAL 2408
+ E K SS+ + K EE K E+ + ++ H
Sbjct: 331 KSIYTTEKSYKCKECGKTFNWSSTLTNHKKTHTEEKPYKCEEYGKAFNQSSNYTTHKVTH 390
Query: 2409 NTEKRFPCEFCGRAFSQGSEWERHVLRH 2436
EK + CE CG+AFSQ S H H
Sbjct: 391 TGEKPYKCEECGKAFSQSSTLTIHKRIH 418
Score = 35.8 bits (81), Expect = 0.54
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C + ++S+H + IH K YKC+EC T S L HK HTG
Sbjct: 648 YKCEECGKAFILSSTLSKH-KRIHTGEKP--YKCEECGKTFNQSSNLSTHKIIHTG 700
Score = 32.3 bits (72), Expect = 6.0
Identities = 18/56 (32%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C + +++ H + IH K YKC+EC S L HK+ HTG
Sbjct: 564 YKCEECGKAFIWSSNLTEH-KKIHTREKP--YKCEECSKAFSRSSALTTHKRMHTG 616
>gi|239746228 PREDICTED: zinc finger protein 726 [Homo sapiens]
Length = 877
Score = 109 bits (273), Expect = 3e-23
Identities = 147/650 (22%), Positives = 227/650 (34%), Gaps = 137/650 (21%)
Query: 1845 PFRCIKCFKLSFSTAELLCM--HYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQ 1902
PF+C C K SF CM H T H S +Y+CK C
Sbjct: 311 PFKCKNCVK-SF------CMFSHKTQHKSI-------------YTTEKSYKCKECGKTFN 350
Query: 1903 STAELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVPKIKE 1962
++ LT+H H EE K K +E K Y H E P
Sbjct: 351 WSSTLTNHKKTHTEE--KPYKCEEYGKAFNQSSNYTTHKVT---------HTGEKP---- 395
Query: 1963 RKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVPA-------VSAAVKGLRSHERSHLA 2015
YKC+ C + + H R H G P + L H+R H+
Sbjct: 396 -----YKCEECGKAFSQSSTLTIHKRIHT--GEKPCKCEECGKAFSQPSALTIHKRMHIG 448
Query: 2016 LAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILK 2075
E Y C+ C + L RH + H G KP++C+ C+ S L TH +
Sbjct: 449 ------EKPYKCEECGKAFVWSSTLTRHKRLHSGE-KPYKCEECAKAFSQFGHLTTHRI- 500
Query: 2076 AHAGEHAYKCSWCSFSTMTISQLKEHSLKVH-----------GKALTLPRPRIVSLLSSH 2124
H GE YKC C + + S L +H ++H GKA R +L
Sbjct: 501 IHTGEKPYKCEECGKAFIWPSTLTKHK-RIHTGEKPYKCEECGKAFH----RSSNLTKHK 555
Query: 2125 SHHSSQKATPAEEVEDSN--DSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAAG 2182
H+ +K EE + S+ +E + + Y+ ++ SR S +
Sbjct: 556 IIHTGEKPYKCEECGKAFIWSSNLTEHKKIHTREKPYKCEECSKAFSRSSALTTHKRMHT 615
Query: 2183 TEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAG 2242
E+ + CE C + ++ H + H G+K +KC++C S + H
Sbjct: 616 GEKPYK----CEECGKAFSQSSTLTAH-KIIHTGEKPYKCEECGKAFILSSTLSKHKRI- 669
Query: 2243 HSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSK--------- 2293
G K +C C N+ H ++H E+ E C ++
Sbjct: 670 -----HTGEKPYKCEECGKTFNQSSNLSTHKIIHTGEKPYKCEECGKAFNRSSNLSTHKI 724
Query: 2294 -YLQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHK 2352
+ ++CD+C + +L +H H KPYKC+ C H++ L H+R HK
Sbjct: 725 IHTGEKPYKCDECGKSFIWSSTLFKHXIIHTGEKPYKCEECGKAFNHSQIL-LHIR--HK 781
Query: 2353 VSRNFELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEK 2412
+M + ++ K ++S F H K
Sbjct: 782 -----------------RMHTGEKPYKCEECGKSFNLSS--------TFIKHKVIHTGVK 816
Query: 2413 RFPCEFCGRAFSQGSEWERHVLRH-----------GMALNDTKQVSREEI 2451
+ CE CG+ F S RH H G A N + ++ ++I
Sbjct: 817 LYKCEECGKVFFWSSALTRHKKIHAGQQPYKWEKIGKAFNQSSHLTTDKI 866
Score = 82.0 bits (201), Expect = 7e-15
Identities = 98/447 (21%), Positives = 161/447 (36%), Gaps = 54/447 (12%)
Query: 2039 NLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQL 2098
NL+R+ + H KPF+CK C KS KT + E +YKC C + S L
Sbjct: 298 NLNRY-KIRHTRKKPFKCKNC-VKSFCMFSHKTQHKSIYTTEKSYKCKECGKTFNWSSTL 355
Query: 2099 KEHSLKVHGKALTLPRPRIVSLLSSHSHHSSQKAT-----PAEEVEDSNDSSYSEPPDVQ 2153
H K H + + S++++ K T P + E S S +
Sbjct: 356 TNHK-KTHTEEKPYKCEEYGKAFNQSSNYTTHKVTHTGEKPYKCEECGKAFSQSSTLTIH 414
Query: 2154 QQLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDK 2213
++++ + + P + E CE C + + ++ RH R
Sbjct: 415 KRIHTGEKPCKCEECGKAFSQPSALTIHKRMHIGEKPYKCEECGKAFVWSSTLTRHKR-L 473
Query: 2214 HGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHI 2273
H G+K +KC++C+ AF+ + G K +C C + + H
Sbjct: 474 HSGEKPYKCEECA------KAFSQFGHLTTHRIIHTGEKPYKCEECGKAFIWPSTLTKHK 527
Query: 2274 VLHREERVVPIEVC------RSKLSK----YLQGVVFRCDKCTFTCSSDESLQQHIEKHN 2323
+H E+ E C S L+K + ++C++C +L +H + H
Sbjct: 528 RIHTGEKPYKCEECGKAFHRSSNLTKHKIIHTGEKPYKCEECGKAFIWSSNLTEHKKIHT 587
Query: 2324 ELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFELVGRVNLDQLEQMKEKMESSSSDDE 2383
KPYKC+ C + L +H R H + + + E+ + SS+
Sbjct: 588 REKPYKCEECSKAFSRSSALTTHKR-MHTGEKPY---------KCEECGKAFSQSSTLTA 637
Query: 2384 DKEEEMNSKAEDRE--------LMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLR 2435
K K E S H EK + CE CG+ F+Q S H +
Sbjct: 638 HKIIHTGEKPYKCEECGKAFILSSTLSKHKRIHTGEKPYKCEECGKTFNQSSNLSTHKII 697
Query: 2436 H-----------GMALNDTKQVSREEI 2451
H G A N + +S +I
Sbjct: 698 HTGEKPYKCEECGKAFNRSSNLSTHKI 724
Score = 53.1 bits (126), Expect = 3e-06
Identities = 128/608 (21%), Positives = 214/608 (35%), Gaps = 108/608 (17%)
Query: 1515 YKCRHCPYINTRIHGVLTHYQKRHPSIK-VTAEDFVHDVEQSADISQNDVEETSRIFKQG 1573
YKC+ C LT+++K H K E++ QS++ + + V T G
Sbjct: 340 YKCKECGK-TFNWSSTLTNHKKTHTEEKPYKCEEYGKAFNQSSNYTTHKVTHT------G 392
Query: 1574 YGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFDVFSQSPPKLPVPLEPEMTTEVSPSQVS 1633
Y+C+ C L IH ++ H + P E PS ++
Sbjct: 393 EKPYKCEECGKAFSQSSTLTIH-KRIHTGEK-----------PCKCEECGKAFSQPSALT 440
Query: 1634 ITEE-EVGEEPVSTSHFSTSHLVSHTV------------FRCQLCKYFCSTRKGIARHYR 1680
I + +GE+P + + S T+ ++C+ C S + H R
Sbjct: 441 IHKRMHIGEKPYKCEECGKAFVWSSTLTRHKRLHSGEKPYKCEECAKAFSQFGHLTTH-R 499
Query: 1681 IKHNNVRAQPEGKNNLFKCALCAYTNPIRKGLAAHYQKRHDIDAYYT--HCLAASRTISD 1738
I H + +KC C L H ++ H + Y C A S+
Sbjct: 500 IIHTGEKP--------YKCEECGKAFIWPSTLTKH-KRIHTGEKPYKCEECGKAFHRSSN 550
Query: 1739 KPNKVIIPSPPKDD-----------SPQLSEELRRAVEKK--KCSLCSFQSFSKKGIVSH 1785
II + K S L+E + +K KC CS ++FS+ ++
Sbjct: 551 LTKHKIIHTGEKPYKCEECGKAFIWSSNLTEHKKIHTREKPYKCEECS-KAFSRSSALTT 609
Query: 1786 YMKRHPGVFPKK-QHASKLGGYFTAVYADE----HEKPTLMEEEERGNFEKAEVEGEAQE 1840
+ + H G P K + K + + A + EKP EE + F + + +
Sbjct: 610 HKRMHTGEKPYKCEECGKAFSQSSTLTAHKIIHTGEKPYKCEECGKA-FILSSTLSKHKR 668
Query: 1841 IEW--LPFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCD 1898
I P++C +C K +F+ + L H H G P Y+C+ C
Sbjct: 669 IHTGEKPYKCEECGK-TFNQSSNLSTHKIIH-----------TGEKP------YKCEECG 710
Query: 1899 SKLQSTAELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVP 1958
++ L++H IH E K K E K + ++ + H E P
Sbjct: 711 KAFNRSSNLSTHKIIHTGE--KPYKCDECGKSFI---------WSSTLFKHXIIHTGEKP 759
Query: 1959 KIKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVP-AVSAAVKGLRSHERSHLALA 2017
YKC+ C + + + + K + G P K
Sbjct: 760 ---------YKCEECGKAFNHSQILLHIRHKRMHTGEKPYKCEECGKSFNLSSTFIKHKV 810
Query: 2018 MFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAH 2077
+ T Y C+ C V + L RH + H G +P++ + + +S L T + H
Sbjct: 811 IHTGVKLYKCEECGKVFFWSSALTRHKKIHAG-QQPYKWEKIGKAFNQSSHLTTDKI-TH 868
Query: 2078 AGEHAYKC 2085
GE +YKC
Sbjct: 869 IGEKSYKC 876
Score = 37.4 bits (85), Expect = 0.19
Identities = 37/148 (25%), Positives = 54/148 (36%), Gaps = 16/148 (10%)
Query: 2296 QGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSR 2355
QG +C K +L ++ +H KP+KC+ C + S HK
Sbjct: 280 QGKASQCGKYLKVFYKFINLNRYKIRHTRKKPFKCKNC---------VKSFCMFSHKTQH 330
Query: 2356 NFELVGRVNLDQLEQMKEKMESSSSDDEDK--EEEMNSKAED-----RELMRFSDHGAAL 2408
+ E K SS+ + K EE K E+ + ++ H
Sbjct: 331 KSIYTTEKSYKCKECGKTFNWSSTLTNHKKTHTEEKPYKCEEYGKAFNQSSNYTTHKVTH 390
Query: 2409 NTEKRFPCEFCGRAFSQGSEWERHVLRH 2436
EK + CE CG+AFSQ S H H
Sbjct: 391 TGEKPYKCEECGKAFSQSSTLTIHKRIH 418
Score = 35.8 bits (81), Expect = 0.54
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C + ++S+H + IH K YKC+EC T S L HK HTG
Sbjct: 648 YKCEECGKAFILSSTLSKH-KRIHTGEKP--YKCEECGKTFNQSSNLSTHKIIHTG 700
Score = 32.3 bits (72), Expect = 6.0
Identities = 18/56 (32%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C + +++ H + IH K YKC+EC S L HK+ HTG
Sbjct: 564 YKCEECGKAFIWSSNLTEH-KKIHTREKP--YKCEECSKAFSRSSALTTHKRMHTG 616
>gi|55769537 zinc finger protein 658 [Homo sapiens]
Length = 1059
Score = 108 bits (271), Expect = 5e-23
Identities = 131/569 (23%), Positives = 214/569 (37%), Gaps = 72/569 (12%)
Query: 1892 YQCKHCDSKLQSTAELTSHLNIHNEE--FQKRAKRQERRKQLLSKQKY-ADGAFADFKQE 1948
Y+C C + L+ HL IH +E + + L+ QK A+ +
Sbjct: 440 YECNECGKAFCQNSNLSKHLRIHTKEKPCDNNGCGRSYKSPLIGHQKTDAEMELCGGSEY 499
Query: 1949 RPFGHLEEVPKIKERKVVGYKCKFCVEVHPTLRAICNHLRKH--VQYGNVPAVSAAVKGL 2006
HL K +R ++G K C+E T +HLR H + G P +
Sbjct: 500 GKTSHL----KGHQRILMGEKPYECIECGKTFSKT-SHLRAHQRIHTGEKPYECVECEKT 554
Query: 2007 RSHERSHLAL--AMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSS 2064
SH ++HL++ + T E Y C C + L H + H G KP+ C C +
Sbjct: 555 FSH-KTHLSVHQRVHTGEKPYECNDCGKSFTYNSALRAHQRIHTGE-KPYECSDCEKTFA 612
Query: 2065 YNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVHGKALTLPRPRIVSLLSSH 2124
+NS L+ H + H GE Y+C+ C S IS LK H RI
Sbjct: 613 HNSALRAHH-RIHTGEKPYECNECGRSFAHISVLKAHQ-------------RI------- 651
Query: 2125 SHHSSQKATPAEEVEDSNDSSYSEPPDVQQQLNH----YQSAALARNNSRVSPVPLSGAA 2180
H+ +K P E E +Y+ Q+++ Y+ + + + S + +
Sbjct: 652 --HTGEK--PYECNECGRSFTYNSALRAHQRIHTGRKPYECSDCEKTFAHNSALKIHQRI 707
Query: 2181 AGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVE 2240
E+ E C CE + + ++R H ++ H G+KL++C +C K+ F
Sbjct: 708 HTGEKPYE----CNECEKTFAHNSALRAH-QNIHTGEKLYECSECG-----KTFFQKTRL 757
Query: 2241 AGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVV- 2299
+ H + G K C C K + H +H E+ VC K Y ++
Sbjct: 758 STHRRI-HTGEKPYECSKCGKTFSQKSYLSGHERIHTGEKPYECNVC-GKTFVYKAALIV 815
Query: 2300 ----------FRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRD 2349
+ C++C T S L H H KPY+C C L +H R
Sbjct: 816 HQRIHTGEKPYECNQCGKTFSQRTHLCAHQRIHTGEKPYECNECGKTFADNSALRAHHRI 875
Query: 2350 EHKVSRNFEL--VGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAA 2407
H + +E G+ + ++ + + S + + E ++ + S H
Sbjct: 876 -HTGEKPYECNDCGKT-FSKTSHLRAHLRTRSGEKPYECSECGKTFSEKSYV--SAHQRV 931
Query: 2408 LNTEKRFPCEFCGRAFSQGSEWERHVLRH 2436
EK + C CG+ F+ S H H
Sbjct: 932 HTGEKPYECNVCGKPFAHNSTLRVHQRIH 960
Score = 91.7 bits (226), Expect = 8e-18
Identities = 137/660 (20%), Positives = 218/660 (33%), Gaps = 149/660 (22%)
Query: 1897 CDSKLQSTAELTSHLNIHNE-------EFQKRAKRQERRKQLLSKQK---------YADG 1940
C L + T+H IH E E K K R+ L+ Q+ Y +
Sbjct: 358 CTDALYQKLDFTAHQRIHTEDKFYLSDEHGKCRKSFYRKAHLIQHQRPHSGEKTYQYEEC 417
Query: 1941 AFADFKQERPFGHLEEVPKIKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQY------- 1993
A + P H K Y+C C + + HLR H +
Sbjct: 418 AKSFCSSSHPIQHPGTYVGFKL-----YECNECGKAFCQNSNLSKHLRIHTKEKPCDNNG 472
Query: 1994 ----------------GNVPAVSAAVKGLRSHERSHLALAM------------------- 2018
+ + G SH + H + M
Sbjct: 473 CGRSYKSPLIGHQKTDAEMELCGGSEYGKTSHLKGHQRILMGEKPYECIECGKTFSKTSH 532
Query: 2019 -------FTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKT 2071
T E Y C C + + +L H + H G KP+ C C +YNS L+
Sbjct: 533 LRAHQRIHTGEKPYECVECEKTFSHKTHLSVHQRVHTG-EKPYECNDCGKSFTYNSALRA 591
Query: 2072 HILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVHGKALTLPRP----------RIVSLL 2121
H + H GE Y+CS C + S L+ H ++H T +P +S+L
Sbjct: 592 H-QRIHTGEKPYECSDCEKTFAHNSALRAHH-RIH----TGEKPYECNECGRSFAHISVL 645
Query: 2122 SSHSH-HSSQKATPAEEVEDSNDSSYSEPPDVQQQLN----HYQSAALARNNSRVSPVPL 2176
+H H+ +K P E E +Y+ Q+++ Y+ + + + S + +
Sbjct: 646 KAHQRIHTGEK--PYECNECGRSFTYNSALRAHQRIHTGRKPYECSDCEKTFAHNSALKI 703
Query: 2177 SGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFT 2236
E+ E C CE + + ++R H ++ H G+KL++C +C K+ +
Sbjct: 704 HQRIHTGEKPYE----CNECEKTFAHNSALRAH-QNIHTGEKLYECSECGKTFFQKTRLS 758
Query: 2237 MHVE-----------------------AGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHI 2273
H +GH + G K C +C YK +I H
Sbjct: 759 THRRIHTGEKPYECSKCGKTFSQKSYLSGHERI-HTGEKPYECNVCGKTFVYKAALIVHQ 817
Query: 2274 VLHREERVVPIEVCRSKLSK----------YLQGVVFRCDKCTFTCSSDESLQQHIEKHN 2323
+H E+ C S+ + + C++C T + + +L+ H H
Sbjct: 818 RIHTGEKPYECNQCGKTFSQRTHLCAHQRIHTGEKPYECNECGKTFADNSALRAHHRIHT 877
Query: 2324 ELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFELVGRVNLDQLEQMKEKMESSSSDDE 2383
KPY+C C T L +HLR G + E K E S
Sbjct: 878 GEKPYECNDCGKTFSKTSHLRAHLRTRS---------GEKPYECSECGKTFSEKSYVSAH 928
Query: 2384 DKEEEMNSKAEDRELMRFSDHGAALNT-------EKRFPCEFCGRAFSQGSEWERHVLRH 2436
+ E + H + L EK + C CG+ FSQ S H H
Sbjct: 929 QRVHTGEKPYECNVCGKPFAHNSTLRVHQRIHTGEKSYECNDCGKTFSQKSHLSAHQRIH 988
Score = 75.1 bits (183), Expect = 8e-13
Identities = 144/686 (20%), Positives = 219/686 (31%), Gaps = 161/686 (23%)
Query: 1439 EQEAECPEDARLSPEKSLQLASANPAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPGMKV 1498
E+ EC E + + S A PY+C C+ +++ L H + H G K
Sbjct: 515 EKPYECIECGKTFSKTSHLRAHQRIHTGEKPYECVECEKTFSHKTHLSVHQ-RVHTGEKP 573
Query: 1499 KAADFAQDIDINPGAVYKCRHCPYINTRIHGVLTHYQKRHPSIKVTAEDFVHDVEQSADI 1558
Y+C C T + L +Q+ H T E +
Sbjct: 574 ----------------YECNDCGKSFT-YNSALRAHQRIH-----TGEKPYECSDCEKTF 611
Query: 1559 SQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFDVFSQSPPKLPVP 1618
+ N G Y C C + + LK H + + ++
Sbjct: 612 AHNSALRAHHRIHTGEKPYECNECGRSFAHISVLKAHQRIHTGEKPYEC----------- 660
Query: 1619 LEPEMTTEVSPSQVSITEEEVGEEPVSTSHFSTSHLVSHT---VFRCQLCKYFCSTRKGI 1675
E G S +H HT + C C+ + +
Sbjct: 661 ------------------NECGRSFTYNSALR-AHQRIHTGRKPYECSDCEKTFAHNSAL 701
Query: 1676 ARHYRIKHNNVRAQPEGKNNLFKCALCAYTNPIRKGLAAHYQKRHDIDAYYTHCLAASRT 1735
H RI H + ++C C T L AH Q H + Y C +T
Sbjct: 702 KIHQRI-HTGEKP--------YECNECEKTFAHNSALRAH-QNIHTGEKLY-ECSECGKT 750
Query: 1736 ISDKPNKVIIPSPPKDDSPQLSEELRRAVEKK--KCSLCSFQSFSKKGIVSHYMKRHPGV 1793
K +LS R +K +CS C ++FS+K +S + + H G
Sbjct: 751 FFQKT--------------RLSTHRRIHTGEKPYECSKCG-KTFSQKSYLSGHERIHTG- 794
Query: 1794 FPKKQHASKLGGYFTAVYADEHEKPTLMEEEERGNFEKAEVEGEAQEIEWLPFRCIKCFK 1853
+K + + G T VY K L+ + EK P+ C +C K
Sbjct: 795 --EKPYECNVCGK-TFVY-----KAALIVHQRIHTGEK-------------PYECNQCGK 833
Query: 1854 LSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNI 1913
+FS LC H H G P Y+C C + L +H I
Sbjct: 834 -TFSQRTHLCAHQRIH-----------TGEKP------YECNECGKTFADNSALRAHHRI 875
Query: 1914 HNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVPKIKERKVVGYKCKFC 1973
H E + + SK + E+P Y+C C
Sbjct: 876 HTGE---KPYECNDCGKTFSKTSHLRAHLRTRSGEKP-----------------YECSEC 915
Query: 1974 VEVHPTLRAICNHLRKHVQYGNVPAVS-------AAVKGLRSHERSHLALAMFTREDKYS 2026
+ + H R H G P A LR H+R H T E Y
Sbjct: 916 GKTFSEKSYVSAHQRVHT--GEKPYECNVCGKPFAHNSTLRVHQRIH------TGEKSYE 967
Query: 2027 CQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCS 2086
C C + + +L H + H G KP+ C C + NS L+ H + H GE Y+C
Sbjct: 968 CNDCGKTFSQKSHLSAHQRIHTGE-KPYECNECGKAFAQNSTLRVH-QRIHTGEKPYECD 1025
Query: 2087 WCSFSTMTISQLKEHSLKVHGKALTL 2112
C + + + L+ H ++H + TL
Sbjct: 1026 ECGKTFVRKAALRVHHTRMHTREKTL 1051
Score = 40.0 bits (92), Expect = 0.029
Identities = 68/301 (22%), Positives = 98/301 (32%), Gaps = 66/301 (21%)
Query: 2152 VQQQLNHYQSAALARNNSRVSPVP-----LSGAAAGTEQKTEAVLHCEFCEFSSGYIQSI 2206
V + HY+ N SR SP+ ++G +A K E E SS +I
Sbjct: 290 VHMAMTHYECNERGINFSRKSPLTQSQRTITGWSAFESNKCE-----ENFSQSSAHIVHQ 344
Query: 2207 RRHYRDKHGGKKLFKCKDCSFYT-GFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKY 2265
+ DK G +C D + F + +H E E G +C Y
Sbjct: 345 KTQAGDKFGEHN--ECTDALYQKLDFTAHQRIHTEDKFYLSDEHG----KCRKSFYR--- 395
Query: 2266 KRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRCDKCTFTCSSDESLQQHIEKHNEL 2325
K ++I H H E+ E C CSS +Q H +
Sbjct: 396 KAHLIQHQRPHSGEKTYQYEECAKSF-----------------CSSSHPIQ-HPGTYVGF 437
Query: 2326 KPYKCQLCYYETKHTEELDSHLR--------DEHKVSRNFE--LVGRVNLDQLEQMKEKM 2375
K Y+C C L HLR D + R+++ L+G
Sbjct: 438 KLYECNECGKAFCQNSNLSKHLRIHTKEKPCDNNGCGRSYKSPLIGH------------- 484
Query: 2376 ESSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLR 2435
D E E+ +E + H L EK + C CG+ FS+ S H
Sbjct: 485 -----QKTDAEMELCGGSEYGKTSHLKGHQRILMGEKPYECIECGKTFSKTSHLRAHQRI 539
Query: 2436 H 2436
H
Sbjct: 540 H 540
Score = 37.0 bits (84), Expect = 0.24
Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C H ++ H +NIH K +Y+C EC T +L H++ HTG
Sbjct: 714 YECNECEKTFAHNSALRAH-QNIHTGEK--LYECSECGKTFFQKTRLSTHRRIHTG 766
Score = 33.5 bits (75), Expect = 2.7
Identities = 17/56 (30%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C H ++ H + IH K+ Y+C++C T L AH++ HTG
Sbjct: 938 YECNVCGKPFAHNSTLRVH-QRIHTGEKS--YECNDCGKTFSQKSHLSAHQRIHTG 990
Score = 32.3 bits (72), Expect = 6.0
Identities = 19/58 (32%), Positives = 32/58 (55%), Gaps = 7/58 (12%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDEC--PFTCKSSLKLGAHKQCHTG 494
++C C H+ +S H + +H K Y+C++C FT S+L+ AH++ HTG
Sbjct: 546 YECVECEKTFSHKTHLSVH-QRVHTGEKP--YECNDCGKSFTYNSALR--AHQRIHTG 598
Score = 32.0 bits (71), Expect = 7.9
Identities = 28/91 (30%), Positives = 37/91 (40%), Gaps = 6/91 (6%)
Query: 406 HQTSGLSAEQLMGSDGNKLLETKGIPFRRFMNR--FQCPFCPFLTMHRRSISRHIENIHL 463
HQ + E GS+ K KG R M ++C C T + S R + IH
Sbjct: 484 HQKTDAEMELCGGSEYGKTSHLKGHQ-RILMGEKPYECIECG-KTFSKTSHLRAHQRIHT 541
Query: 464 SGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
K Y+C EC T L H++ HTG
Sbjct: 542 GEKP--YECVECEKTFSHKTHLSVHQRVHTG 570
>gi|222831664 zinc finger protein 184 [Homo sapiens]
Length = 751
Score = 108 bits (270), Expect = 7e-23
Identities = 130/521 (24%), Positives = 181/521 (34%), Gaps = 100/521 (19%)
Query: 1845 PFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQST 1904
P++C +C K +FS +E L H H G+ P Y+C C
Sbjct: 249 PYKCNECEK-AFSRSENLINHQRIH-----------TGDKP------YKCDQCGKGFIEG 290
Query: 1905 AELTSHLNIHNEEFQKRA----KRQERRKQLLSKQKYADGAFADFKQERPF--------- 1951
LT H IH E + K +R L+ Q+ G E+P+
Sbjct: 291 PSLTQHQRIHTGEKPYKCDECGKAFSQRTHLVQHQRIHTG-------EKPYTCNECGKAF 343
Query: 1952 ---GHLEEVPKIKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVPA--VSAAVKGL 2006
GH E KI + +KC C + + H + H A G
Sbjct: 344 SQRGHFMEHQKIHTGEKP-FKCDECDKTFTRSTHLTQHQKIHTGEKTYKCNECGKAFNGP 402
Query: 2007 RSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYN 2066
+ R H+ + T E Y C C + NL +H +TH G KP+ C C SY
Sbjct: 403 STFIRHHM---IHTGEKPYECNECGKAFSQHSNLTQHQKTHTGE-KPYDCAECGKSFSYW 458
Query: 2067 SRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVHGKALTLPRPRIVSLLSSHSH 2126
S L H LK H GE YKC+ C + S L +H RI
Sbjct: 459 SSLAQH-LKIHTGEKPYKCNECGKAFSYCSSLTQHR-------------RI--------- 495
Query: 2127 HSSQKATPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAAGTEQK 2186
H+ +K P E E SY + Q Q H Q A + + S A
Sbjct: 496 HTREK--PFECSECGKAFSYLSNLN-QHQKTHTQEKAYECKECGKAFIRSSSLAKHERIH 552
Query: 2187 T-EAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSA 2245
T E C C + Y S+ +H R H G++ +KC +C AF ++
Sbjct: 553 TGEKPYQCHECGKTFSYGSSLIQH-RKIHTGERPYKCNECG------RAFNQNIHLTQHK 605
Query: 2246 VPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRCDKC 2305
G K C C ++ ++ H H EE+ ++C+KC
Sbjct: 606 RIHTGAKPYECAECGKAFRHCSSLAQHQKTHTEEKP------------------YQCNKC 647
Query: 2306 TFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSH 2346
T S L QH H KPYKC C + L H
Sbjct: 648 EKTFSQSSHLTQHQRIHTGEKPYKCNECDKAFSRSTHLTEH 688
Score = 94.0 bits (232), Expect = 2e-18
Identities = 118/500 (23%), Positives = 170/500 (34%), Gaps = 116/500 (23%)
Query: 1968 YKCKFCVEVHPTLRAICNHLRKHVQYGNVP-----AVSAAVKG--LRSHERSHLALAMFT 2020
YKC C + + NH R H G+ P ++G L H+R H T
Sbjct: 250 YKCNECEKAFSRSENLINHQRIHT--GDKPYKCDQCGKGFIEGPSLTQHQRIH------T 301
Query: 2021 REDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGE 2080
E Y C C + R +L +H + H G KP+ C C S H K H GE
Sbjct: 302 GEKPYKCDECGKAFSQRTHLVQHQRIHTGE-KPYTCNECGKAFSQRGHFMEH-QKIHTGE 359
Query: 2081 HAYKCSWCSFSTMTISQLKEHSLKVH-----------GKALTLPRPRIVSLLSSHSHHSS 2129
+KC C + + L +H K+H GKA P + + H H+
Sbjct: 360 KPFKCDECDKTFTRSTHLTQHQ-KIHTGEKTYKCNECGKAFNGPS----TFIRHHMIHTG 414
Query: 2130 QKATPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAAGTEQKT-- 2187
+K E ++S+ ++ Q QKT
Sbjct: 415 EKPYECNEC----GKAFSQHSNLTQH-----------------------------QKTHT 441
Query: 2188 -EAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAV 2246
E C C S Y S+ +H + H G+K +KC +C + S+ T H
Sbjct: 442 GEKPYDCAECGKSFSYWSSLAQHLKI-HTGEKPYKCNECGKAFSYCSSLTQHRRIHTREK 500
Query: 2247 PEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVC------RSKLSKYLQ---- 2296
P E C C Y N+ H H +E+ + C S L+K+ +
Sbjct: 501 PFE------CSECGKAFSYLSNLNQHQKTHTQEKAYECKECGKAFIRSSSLAKHERIHTG 554
Query: 2297 GVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRN 2356
++C +C T S SL QH + H +PYKC C L H R H ++
Sbjct: 555 EKPYQCHECGKTFSYGSSLIQHRKIHTGERPYKCNECGRAFNQNIHLTQHKRI-HTGAKP 613
Query: 2357 FELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPC 2416
+E E K SS + H EK + C
Sbjct: 614 YECA--------ECGKAFRHCSS---------------------LAQHQKTHTEEKPYQC 644
Query: 2417 EFCGRAFSQGSEWERHVLRH 2436
C + FSQ S +H H
Sbjct: 645 NKCEKTFSQSSHLTQHQRIH 664
Score = 75.9 bits (185), Expect = 5e-13
Identities = 90/418 (21%), Positives = 141/418 (33%), Gaps = 65/418 (15%)
Query: 2021 REDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGE 2080
+E C C ++ L RH +TH G KP++C C S + L H + H G+
Sbjct: 218 KEKSCKCNECGKAFSYCSALIRHQRTHTGE-KPYKCNECEKAFSRSENLINH-QRIHTGD 275
Query: 2081 HAYKCSWCSFSTMTISQLKEHSLKVHGKALTLPRPRIVSLLSSHSHH-SSQKATPAEEVE 2139
YKC C + L +H ++H S +H Q+ E+
Sbjct: 276 KPYKCDQCGKGFIEGPSLTQHQ-RIHTGEKPYKCDECGKAFSQRTHLVQHQRIHTGEKPY 334
Query: 2140 DSNDSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFS 2199
N+ + Q H+ E C+ C+ +
Sbjct: 335 TCNECGKAF-----SQRGHFMEHQKIHTG-------------------EKPFKCDECDKT 370
Query: 2200 SGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLC 2259
+ +H + H G+K +KC +C S F H + G K C C
Sbjct: 371 FTRSTHLTQHQKI-HTGEKTYKCNECGKAFNGPSTFIRH------HMIHTGEKPYECNEC 423
Query: 2260 LYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRCDKCTFTCSSDESLQQHI 2319
N+ H H E+ + C +C + S SL QH+
Sbjct: 424 GKAFSQHSNLTQHQKTHTGEKP------------------YDCAECGKSFSYWSSLAQHL 465
Query: 2320 EKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFEL--VGRVNLDQLEQMKEKMES 2377
+ H KPYKC C + L H R H + FE G+ L + + ++
Sbjct: 466 KIHTGEKPYKCNECGKAFSYCSSLTQH-RRIHTREKPFECSECGKA-FSYLSNLNQHQKT 523
Query: 2378 SSSDDEDKEEEMNSKAEDRELMRFSD---HGAALNTEKRFPCEFCGRAFSQGSEWERH 2432
+ +E+ K + +R S H EK + C CG+ FS GS +H
Sbjct: 524 HT-----QEKAYECKECGKAFIRSSSLAKHERIHTGEKPYQCHECGKTFSYGSSLIQH 576
Score = 42.4 bits (98), Expect = 0.006
Identities = 128/668 (19%), Positives = 205/668 (30%), Gaps = 176/668 (26%)
Query: 1430 ENSIPTPFPEQEAECPEDARLSPEKSLQLASANPAISSTPYQCTVCQSEYNNLHGLLTHY 1489
+NS P E+ +C E + S + PY+C C+ ++ L+ H
Sbjct: 211 QNSNPVK-KEKSCKCNECGKAFSYCSALIRHQRTHTGEKPYKCNECEKAFSRSENLINHQ 269
Query: 1490 GKKHPGMK-----------VKAADFAQDIDINPGAV-YKCRHC-PYINTRIHGVLTHYQK 1536
+ H G K ++ Q I+ G YKC C + R H L +Q+
Sbjct: 270 -RIHTGDKPYKCDQCGKGFIEGPSLTQHQRIHTGEKPYKCDECGKAFSQRTH--LVQHQR 326
Query: 1537 RHPSIK-VTAEDFVHDVEQSADISQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIH 1595
H K T + Q ++ T G ++C C T L H
Sbjct: 327 IHTGEKPYTCNECGKAFSQRGHFMEHQKIHT------GEKPFKCDECDKTFTRSTHLTQH 380
Query: 1596 YE--------------KYHNQPEFDVFSQSPPKLPVPLEPEMTTEVSPSQVSITEEE--- 1638
+ K N P + P E + ++T+ +
Sbjct: 381 QKIHTGEKTYKCNECGKAFNGPSTFIRHHMIHTGEKPYECNECGKAFSQHSNLTQHQKTH 440
Query: 1639 VGEEPV-------STSHFST--SHLVSHT---VFRCQLCKYFCSTRKGIARHYRIKHNNV 1686
GE+P S S++S+ HL HT ++C C S + +H RI +
Sbjct: 441 TGEKPYDCAECGKSFSYWSSLAQHLKIHTGEKPYKCNECGKAFSYCSSLTQHRRI---HT 497
Query: 1687 RAQPEGKNNLFKCALCAYTNPIRKGLAAHYQKRHDIDAYYTHCLAASRTISDKPNKVIIP 1746
R +P F+C+ C L H QK H + Y C +
Sbjct: 498 REKP------FECSECGKAFSYLSNLNQH-QKTHTQEKAY-ECKECGKAFI--------- 540
Query: 1747 SPPKDDSPQLSEELRRAVEKKKCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGY 1806
+ S E + + +C C ++FS + + K H G P K ++ G
Sbjct: 541 ---RSSSLAKHERIHTGEKPYQCHECG-KTFSYGSSLIQHRKIHTGERPYK--CNECGRA 594
Query: 1807 FTA-VYADEHEKPTLMEEEERGNFEKAEVEGEAQEIEWLPFRCIKCFKLSFSTAELLCMH 1865
F ++ +H++ + A+ P+ C +C K +F L H
Sbjct: 595 FNQNIHLTQHKR----------------IHTGAK-----PYECAECGK-AFRHCSSLAQH 632
Query: 1866 YTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHNEEFQKRA--- 1922
H + YQC C+ ++ LT H IH E +
Sbjct: 633 QKTH-----------------TEEKPYQCNKCEKTFSQSSHLTQHQRIHTGEKPYKCNEC 675
Query: 1923 -KRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVPKIKERKVVGYKCKFCVEVHPTLR 1981
K R L Q G E+P+
Sbjct: 676 DKAFSRSTHLTEHQNTHTG-------EKPYN----------------------------- 699
Query: 1982 AICNHLRKHVQYGNVPAVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLD 2041
CN RK L H+R H + E + C C +R L+
Sbjct: 700 --CNECRKTFSQSTY---------LIQHQRIH------SGEKPFGCNDCGKSFRYRSALN 742
Query: 2042 RHMQTHHG 2049
+H + H G
Sbjct: 743 KHQRLHPG 750
Score = 32.7 bits (73), Expect = 4.6
Identities = 18/56 (32%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
+QC C + S+ +H IH + YKC+EC ++ L HK+ HTG
Sbjct: 558 YQCHECGKTFSYGSSLIQH-RKIHTGERP--YKCNECGRAFNQNIHLTQHKRIHTG 610
Score = 32.0 bits (71), Expect = 7.9
Identities = 18/56 (32%), Positives = 25/56 (44%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
+QC C +++H + IH K YKC+EC S L H+ HTG
Sbjct: 642 YQCNKCEKTFSQSSHLTQH-QRIHTGEKP--YKCNECDKAFSRSTHLTEHQNTHTG 694
>gi|57165428 zinc finger protein 28 [Homo sapiens]
Length = 665
Score = 103 bits (256), Expect = 3e-21
Identities = 124/532 (23%), Positives = 193/532 (36%), Gaps = 94/532 (17%)
Query: 1846 FRCIKCFKLSFSTAELLCMHYTDH-HSRDLKRD----------FIILGNGPRLQNSTYQC 1894
F+CI+ K SF+ + LL H H + K D ++ + Y+C
Sbjct: 162 FQCIESGK-SFNCSSLLKKHQITHLEEKQCKCDVYGKVFNQKRYLACHRRSHIDEKPYKC 220
Query: 1895 KHCDSKLQSTAELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERPFGHL 1954
C L H +H + + E ++ S++ + + + +P
Sbjct: 221 NECGKIFGHNTSLFLHKALHTAD---KPYECEECDKVFSRKSHLETHKIIYTGGKP---- 273
Query: 1955 EEVPKIKERKVVGYKCKFCVEVHPTLRAICN-HLRKH--VQYGNVP-------AVSAAVK 2004
YKCK C + CN +L KH + G P V +
Sbjct: 274 -------------YKCKVCDKAFT-----CNSYLAKHTIIHTGEKPYKCNECGKVFNRLS 315
Query: 2005 GLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSS 2064
L H R H T E Y C+ C V + + +L+RH + H G KP++CK+C +
Sbjct: 316 TLARHRRLH------TGEKPYECEECEKVFSRKSHLERHKRIHTGE-KPYKCKVCDKAFA 368
Query: 2065 YNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVHGKALTLPRP--------- 2115
YNS L H + H GE YKC+ C +Q + +L H + T +P
Sbjct: 369 YNSYLAKHSI-IHTGEKPYKCNECG---KVFNQ--QSTLARHHRLHTAEKPYKCEECDKV 422
Query: 2116 -RIVSLLSSHSH-HSSQKATPAEEVEDS--NDSSYSEPPDVQQQLNHYQSAALARNNSRV 2171
R S L H H+ +K + + + +DS +E Q+++ + + +V
Sbjct: 423 FRCKSHLERHRRIHTGEKPYKCKVCDKAFRSDSCLTE----HQRVHTGEKPYMCNECGKV 478
Query: 2172 SPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGF 2231
+ A E CE CE + RH R H G+K +KCK C
Sbjct: 479 FSTKANLACHHKLHTAEKPYKCEECEKVFSRKSHMERH-RRIHTGEKPYKCKVCD----- 532
Query: 2232 KSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKL 2291
AF G K +C C + ++I H LH E+ C
Sbjct: 533 -KAFRRDSHLAQHQRVHTGEKPYKCNECGKTFRQTSSLIIHRRLHTGEKPYKCNECGKTF 591
Query: 2292 SKYLQGVV----------FRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLC 2333
S+ V ++C++C + L QH H KPYKC C
Sbjct: 592 SQMSSLVYHHRLHSGEKPYKCNECGKVFNQQAHLAQHQRVHTGEKPYKCNEC 643
Score = 92.8 bits (229), Expect = 4e-18
Identities = 113/489 (23%), Positives = 170/489 (34%), Gaps = 40/489 (8%)
Query: 1969 KCKFCVEVHPTLRAICNHLRKHVQYGNVPAVSAAVKGLRSHERS-HLALAMFTREDKYSC 2027
KC +V R + H R H+ P + H S L A+ T + Y C
Sbjct: 191 KCDVYGKVFNQKRYLACHRRSHID--EKPYKCNECGKIFGHNTSLFLHKALHTADKPYEC 248
Query: 2028 QYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSW 2087
+ C V + + +L+ H + G KP++CK+C + NS L H + H GE YKC+
Sbjct: 249 EECDKVFSRKSHLETHKIIYTGG-KPYKCKVCDKAFTCNSYLAKHTI-IHTGEKPYKCNE 306
Query: 2088 CSFSTMTISQLKEHSLKVHGKALTLPRPRIVSLLSSHSH-------HSSQKATPAEEVED 2140
C +S L H ++H + S SH H+ +K + +
Sbjct: 307 CGKVFNRLSTLARHR-RLHTGEKPYECEECEKVFSRKSHLERHKRIHTGEKPYKCKVCDK 365
Query: 2141 SNDSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSS 2200
+ +Y+ ++ + +V + A E CE C+
Sbjct: 366 A--FAYNSYLAKHSIIHTGEKPYKCNECGKVFNQQSTLARHHRLHTAEKPYKCEECDKVF 423
Query: 2201 GYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCL 2260
+ RH R H G+K +KCK C S T H G K C C
Sbjct: 424 RCKSHLERHRRI-HTGEKPYKCKVCDKAFRSDSCLTEHQRV------HTGEKPYMCNECG 476
Query: 2261 YHTKYKRNMIDHIVLHREERVVPIEVCRSKLSK----------YLQGVVFRCDKCTFTCS 2310
K N+ H LH E+ E C S+ + ++C C
Sbjct: 477 KVFSTKANLACHHKLHTAEKPYKCEECEKVFSRKSHMERHRRIHTGEKPYKCKVCDKAFR 536
Query: 2311 SDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFEL--VGRVNLDQL 2368
D L QH H KPYKC C + T L H R H + ++ G+
Sbjct: 537 RDSHLAQHQRVHTGEKPYKCNECGKTFRQTSSLIIH-RRLHTGEKPYKCNECGKT----F 591
Query: 2369 EQMKEKMESSSSDDEDKEEEMNSKAE-DRELMRFSDHGAALNTEKRFPCEFCGRAFSQGS 2427
QM + +K + N + + + H EK + C CG+ FSQ S
Sbjct: 592 SQMSSLVYHHRLHSGEKPYKCNECGKVFNQQAHLAQHQRVHTGEKPYKCNECGKTFSQMS 651
Query: 2428 EWERHVLRH 2436
H H
Sbjct: 652 NLVYHHRLH 660
Score = 69.7 bits (169), Expect = 3e-11
Identities = 105/470 (22%), Positives = 167/470 (35%), Gaps = 92/470 (19%)
Query: 1652 SHLVSHTV-------FRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCALCAY 1704
SHL +H + ++C++C + +A+H I H + +KC C
Sbjct: 259 SHLETHKIIYTGGKPYKCKVCDKAFTCNSYLAKH-TIIHTGEKP--------YKCNECGK 309
Query: 1705 TNPIRKGLAAHYQKRHDIDAYYTHCLAASRTISDKPNKVIIPSPPKDDSPQLSEELRRAV 1764
LA H ++ H + Y C + S K + + + +
Sbjct: 310 VFNRLSTLARH-RRLHTGEKPY-ECEECEKVFSRKSHL------------ERHKRIHTGE 355
Query: 1765 EKKKCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGYFTAVYADEHEKPTLMEEE 1824
+ KC +C ++F+ ++ + H G P K ++ G F +++ TL
Sbjct: 356 KPYKCKVCD-KAFAYNSYLAKHSIIHTGEKPYK--CNECGKVF-------NQQSTLARHH 405
Query: 1825 ERGNFEKAEVEGEAQEIEWLPFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNG 1884
EK P++C +C K+ C + + H R I G
Sbjct: 406 RLHTAEK-------------PYKCEECDKV------FRCKSHLERHRR------IHTGEK 440
Query: 1885 PRLQNSTYQCKHCDSKLQSTAELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFAD 1944
P Y+CK CD +S + LT H +H E K E K +K A
Sbjct: 441 P------YKCKVCDKAFRSDSCLTEHQRVHTGE--KPYMCNECGKVFSTKANLACHHKLH 492
Query: 1945 FKQERPFGHLEEVPKIKERKV------------VGYKCKFCVEVHPTLRAICNHLRKHVQ 1992
E+P+ EE K+ RK YKCK C + + H R H
Sbjct: 493 -TAEKPY-KCEECEKVFSRKSHMERHRRIHTGEKPYKCKVCDKAFRRDSHLAQHQRVHT- 549
Query: 1993 YGNVP-AVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHH 2051
G P + K R + + T E Y C C + +L H + H G
Sbjct: 550 -GEKPYKCNECGKTFRQTSSLIIHRRLHTGEKPYKCNECGKTFSQMSSLVYHHRLHSGE- 607
Query: 2052 KPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEH 2101
KP++C C + + L H + H GE YKC+ C + +S L H
Sbjct: 608 KPYKCNECGKVFNQQAHLAQH-QRVHTGEKPYKCNECGKTFSQMSNLVYH 656
Score = 34.7 bits (78), Expect = 1.2
Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 7/58 (12%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECP--FTCKSSLKLGAHKQCHTG 494
++C C + + +++RH +H + K YKC+EC F CKS L+ H++ HTG
Sbjct: 386 YKCNECGKVFNQQSTLARH-HRLHTAEKP--YKCEECDKVFRCKSHLE--RHRRIHTG 438
Score = 33.9 bits (76), Expect = 2.1
Identities = 85/437 (19%), Positives = 135/437 (30%), Gaps = 78/437 (17%)
Query: 1195 CQHCDYG----NRTVKGVLIHYQKKHRDFKANADVIRQHTATIRSLCDRNQKKPASC--- 1247
C+ CD + K +IH +K V + + R +KP C
Sbjct: 276 CKVCDKAFTCNSYLAKHTIIHTGEKPYKCNECGKVFNRLSTLARHRRLHTGEKPYECEEC 335
Query: 1248 --VLVSPSNLERDK---TKLRALKCRQCSYTSPYFYALRKHIKKDHPALKATVTSIMRWA 1302
V S+LER K T + KC+ C Y L KH SI+
Sbjct: 336 EKVFSRKSHLERHKRIHTGEKPYKCKVCDKAFAYNSYLAKH-------------SIIHTG 382
Query: 1303 FLDGLIEAGYHCEWCIYSHTEPNGLLLHYQRRHPEHYVDYTYMATKLWAGPDPSPPSLTM 1362
E Y C C + + L H+ R H K++ +
Sbjct: 383 ------EKPYKCNECGKVFNQQSTLARHH-RLHTAEKPYKCEECDKVFRCKSHLERHRRI 435
Query: 1363 PAEAKTYRCRDCVFEAVSIWDITNHYQAFHPWAMNGDESVLLDIIKEKDAVEKPILSSE- 1421
K Y+C+ C S +T H Q H EKP + +E
Sbjct: 436 HTGEKPYKCKVCDKAFRSDSCLTEH-QRVHTG-------------------EKPYMCNEC 475
Query: 1422 ----ELAGPVNCENSIPTPFPEQEAECPEDARLSPEKSLQLASANPAISSTPYQCTVCQS 1477
+ C + + T E+ +C E ++ KS PY+C VC
Sbjct: 476 GKVFSTKANLACHHKLHTA--EKPYKCEECEKVFSRKSHMERHRRIHTGEKPYKCKVCDK 533
Query: 1478 EYNNLHGLLTHYGKKHPGMKVKAAD-----FAQDIDI-------NPGAVYKCRHCPYINT 1525
+ L H + H G K + F Q + YKC C +
Sbjct: 534 AFRRDSHLAQHQ-RVHTGEKPYKCNECGKTFRQTSSLIIHRRLHTGEKPYKCNECGKTFS 592
Query: 1526 RIHGVLTHYQKRHPSIKVTAEDFVHDVEQSADISQNDVEETSRIFKQGYGAYRCKLCPYT 1585
++ ++ H++ + Q A ++Q+ T G Y+C C T
Sbjct: 593 QMSSLVYHHRLHSGEKPYKCNECGKVFNQQAHLAQHQRVHT------GEKPYKCNECGKT 646
Query: 1586 HGTLEKLKIHYEKYHNQ 1602
+ L H+ + +
Sbjct: 647 FSQMSNLVYHHRLHSGE 663
Score = 32.3 bits (72), Expect = 6.0
Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 4/82 (4%)
Query: 106 KFFQCKFCVRYFRSKNLLIEHTRKVHGAQAEGSSSGPPVPGSLNYNIMMHEGF---GKVF 162
K ++CK C + FRS + L EH R VH + + S N+ H K +
Sbjct: 440 KPYKCKVCDKAFRSDSCLTEHQR-VHTGEKPYMCNECGKVFSTKANLACHHKLHTAEKPY 498
Query: 163 SCQFCTYKSPRRARIIKHQKMY 184
C+ C R++ + +H++++
Sbjct: 499 KCEECEKVFSRKSHMERHRRIH 520
Score = 32.3 bits (72), Expect = 6.0
Identities = 16/56 (28%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C +++H + +H K YKC+EC T + + L H++ HTG
Sbjct: 526 YKCKVCDKAFRRDSHLAQH-QRVHTGEKP--YKCNECGKTFRQTSSLIIHRRLHTG 578
Score = 32.0 bits (71), Expect = 7.9
Identities = 37/157 (23%), Positives = 59/157 (37%), Gaps = 12/157 (7%)
Query: 2287 CRSKLSKY----LQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEE 2342
C S L K+ L+ +CD + L H H + KPYKC C H
Sbjct: 173 CSSLLKKHQITHLEEKQCKCDVYGKVFNQKRYLACHRRSHIDEKPYKCNECGKIFGHNTS 232
Query: 2343 LDSHLRDEHKVSRNFELVGRVNLDQLEQMKEKMESSS---SDDEDKEEEMNSKAEDRELM 2399
L H + H + +E D++ K +E+ + + + ++ KA
Sbjct: 233 LFLH-KALHTADKPYEC---EECDKVFSRKSHLETHKIIYTGGKPYKCKVCDKAFTCN-S 287
Query: 2400 RFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRH 2436
+ H EK + C CG+ F++ S RH H
Sbjct: 288 YLAKHTIIHTGEKPYKCNECGKVFNRLSTLARHRRLH 324
>gi|190194429 zinc finger protein 267 [Homo sapiens]
Length = 743
Score = 102 bits (253), Expect = 6e-21
Identities = 115/503 (22%), Positives = 184/503 (36%), Gaps = 67/503 (13%)
Query: 1872 RDLKRDFIILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHNEEFQKRAKRQERRKQL 1931
++ + F+ +G Q +Y+C C + + H IH R+
Sbjct: 247 KEFEEVFLQSMHGQEKQEQSYKCNKCVEVCTQSLKHIQHQTIHI------------RENS 294
Query: 1932 LSKQKYADGAFADFKQERPFGHLEEVPKIKERKVVGYKCKFCVEVHPTLRAICNHLRKHV 1991
S KY + H EE P YKC+ C + NH
Sbjct: 295 YSYNKYDKDLSQSSNLRKQIIHNEEKP---------YKCEKCGDS-------LNHSLHLT 338
Query: 1992 QYGNVPAVSAAVKGLRSHERSHLALAMF--------TREDKYSCQYCSFVSAFRHNLDRH 2043
Q+ +P K + +L +++ T E+ Y C+ CS NL H
Sbjct: 339 QHQIIPTEEKPYKWKECGKVFNLNCSLYLTKQQQIDTGENLYKCKACSKSFTRSSNLIVH 398
Query: 2044 MQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSL 2103
+ H G KP++CK C +S L H + H GE YKC C + S L +H
Sbjct: 399 QRIHTGE-KPYKCKECGKAFRCSSYLTKH-KRIHTGEKPYKCKECGKAFNRSSCLTQHQT 456
Query: 2104 KVHGKAL------TLPRPRIVSLLSSHSHHSSQKATPAEEVED--SNDSSYSEPPDVQQQ 2155
G+ L + R +L+ H+ +K +E S S ++ +
Sbjct: 457 THTGEKLYKCKVCSKSYARSSNLIMHQRVHTGEKPYKCKECGKVFSRSSCLTQHRKIHTG 516
Query: 2156 LNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHG 2215
N Y+ A+ + S + + E+ + C+ C + Y + RH+R H
Sbjct: 517 ENLYKCKVCAKPFTCFSNLIVHERIHTGEKPYK----CKECGKAFPYSSHLIRHHRI-HT 571
Query: 2216 GKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVL 2275
G+K +KCK CS S T+H G K C C Y ++I H +
Sbjct: 572 GEKPYKCKACSKSFSDSSGLTVHRRT------HTGEKPYTCKECGKAFSYSSDVIQHRRI 625
Query: 2276 HREERVVPIEVC------RSKLSKYLQGVV----FRCDKCTFTCSSDESLQQHIEKHNEL 2325
H +R E C RS L+ + + ++C++C +S L H +H
Sbjct: 626 HTGQRPYKCEECGKAFNYRSYLTTHQRSHTGERPYKCEECGKAFNSRSYLTTHRRRHTGE 685
Query: 2326 KPYKCQLCYYETKHTEELDSHLR 2348
+PYKC C + L +H R
Sbjct: 686 RPYKCDECGKAFSYRSYLTTHRR 708
Score = 43.1 bits (100), Expect = 0.003
Identities = 58/250 (23%), Positives = 95/250 (38%), Gaps = 41/250 (16%)
Query: 2192 HCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGP 2251
HC E + S + H ++ + +K +KCK+ F+ F + E+
Sbjct: 217 HCNNSEKTLNQSSSPKNH-QENYFLEKQYKCKE------FEEVFLQSMHG-----QEKQE 264
Query: 2252 KDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRCDKCTFTCSS 2311
+ +C C+ I H +H E +KY DK S
Sbjct: 265 QSYKCNKCVEVCTQSLKHIQHQTIHIRENSY-------SYNKY--------DK---DLSQ 306
Query: 2312 DESLQQHIEKHNELKPYKCQLCYYETKHTEELDSH--LRDEHKVSRNFELVGRVNLDQLE 2369
+L++ I HNE KPYKC+ C H+ L H + E K + E NL+
Sbjct: 307 SSNLRKQII-HNEEKPYKCEKCGDSLNHSLHLTQHQIIPTEEKPYKWKECGKVFNLNCSL 365
Query: 2370 QMKEKMESSSSDDEDKEEEMNSKAEDRELMRFSD---HGAALNTEKRFPCEFCGRAFSQG 2426
+ ++ + + ++ K KA + R S+ H EK + C+ CG+AF
Sbjct: 366 YLTKQQQIDTGENLYK-----CKACSKSFTRSSNLIVHQRIHTGEKPYKCKECGKAFRCS 420
Query: 2427 SEWERHVLRH 2436
S +H H
Sbjct: 421 SYLTKHKRIH 430
Score = 35.0 bits (79), Expect = 0.93
Identities = 49/213 (23%), Positives = 82/213 (38%), Gaps = 51/213 (23%)
Query: 770 KEPNFRNITHDYNATNGAEIELTLSEDEEDYY-----GSSTN----LKDHQVSNTA---- 816
+E ++ +D + + + + + +EE Y G S N L HQ+ T
Sbjct: 291 RENSYSYNKYDKDLSQSSNLRKQIIHNEEKPYKCEKCGDSLNHSLHLTQHQIIPTEEKPY 350
Query: 817 -------LLNTQTPIYGTEHNSENTDFGDSGRLYYCKHCDFNNKSARSVSTHYQRMH--- 866
+ N +Y T+ + D G++ LY CK C + + ++ H QR+H
Sbjct: 351 KWKECGKVFNLNCSLYLTKQ--QQIDTGEN--LYKCKACSKSFTRSSNLIVH-QRIHTGE 405
Query: 867 -PY----IKFSFRYILDPNDHSAV------YRCLECYIDYTNFEDLQQHYGEHHPEAMNV 915
PY +FR H + Y+C EC + L QH H E
Sbjct: 406 KPYKCKECGKAFRCSSYLTKHKRIHTGEKPYKCKECGKAFNRSSCLTQHQTTHTGEK--- 462
Query: 916 LNFDHSDLIYRCRFCSYTSPNVRSLMPHYQRMH 948
+Y+C+ CS + +L+ H QR+H
Sbjct: 463 --------LYKCKVCSKSYARSSNLIMH-QRVH 486
Score = 34.7 bits (78), Expect = 1.2
Identities = 56/273 (20%), Positives = 91/273 (33%), Gaps = 57/273 (20%)
Query: 1470 YQCTVCQSEYNNLHGLLTHYGKKHPGMKVKAADFAQDIDINPGAVYKCRHCPYINTRIHG 1529
Y+C VC Y L+ H + H G K YKC+ C + +R
Sbjct: 464 YKCKVCSKSYARSSNLIMHQ-RVHTGEK----------------PYKCKECGKVFSR-SS 505
Query: 1530 VLTHYQKRHP-----SIKVTAEDF-------VHDVEQSADISQNDVEETSRIF------- 1570
LT ++K H KV A+ F VH+ + + +E + F
Sbjct: 506 CLTQHRKIHTGENLYKCKVCAKPFTCFSNLIVHERIHTGE-KPYKCKECGKAFPYSSHLI 564
Query: 1571 -----KQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFDVFSQSPPKLPVPLEPEMTT 1625
G Y+CK C + L +H + + + + +
Sbjct: 565 RHHRIHTGEKPYKCKACSKSFSDSSGLTVHRRTHTGEKPY-TCKECGKAFSYSSDVIQHR 623
Query: 1626 EVSPSQVSITEEEVGEEPVSTSHFSTSHLVSHT---VFRCQLCKYFCSTRKGIARHYRIK 1682
+ Q EE G + + + T+H SHT ++C+ C ++R + H R +
Sbjct: 624 RIHTGQRPYKCEECG-KAFNYRSYLTTHQRSHTGERPYKCEECGKAFNSRSYLTTHRR-R 681
Query: 1683 HNNVRAQPEGKNNLFKCALCAYTNPIRKGLAAH 1715
H R +KC C R L H
Sbjct: 682 HTGERP--------YKCDECGKAFSYRSYLTTH 706
Score = 34.3 bits (77), Expect = 1.6
Identities = 22/93 (23%), Positives = 42/93 (45%), Gaps = 8/93 (8%)
Query: 95 QHIAANPKPTNKFFQCKFCVRYFRSKNLLIEHTRKVHGAQAEGSSSGPPVPGSLNYNIMM 154
Q + KP ++CK C + F + L +H RK+H + P + N+++
Sbjct: 483 QRVHTGEKP----YKCKECGKVFSRSSCLTQH-RKIHTGENLYKCKVCAKPFTCFSNLIV 537
Query: 155 HEGF---GKVFSCQFCTYKSPRRARIIKHQKMY 184
HE K + C+ C P + +I+H +++
Sbjct: 538 HERIHTGEKPYKCKECGKAFPYSSHLIRHHRIH 570
Score = 33.5 bits (75), Expect = 2.7
Identities = 39/157 (24%), Positives = 57/157 (36%), Gaps = 21/157 (13%)
Query: 1439 EQEAECPEDARLSPEKSLQLASANPAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPGMKV 1498
E+ +C E + P S + PY+C C +++ GL H + H G K
Sbjct: 545 EKPYKCKECGKAFPYSSHLIRHHRIHTGEKPYKCKACSKSFSDSSGLTVH-RRTHTGEKP 603
Query: 1499 -------KAADFAQDI----DINPG-AVYKCRHC-PYINTRIHGVLTHYQKRHPSIKVTA 1545
KA ++ D+ I+ G YKC C N R + LT +Q+ H T
Sbjct: 604 YTCKECGKAFSYSSDVIQHRRIHTGQRPYKCEECGKAFNYRSY--LTTHQRSH-----TG 656
Query: 1546 EDFVHDVEQSADISQNDVEETSRIFKQGYGAYRCKLC 1582
E E + T R G Y+C C
Sbjct: 657 ERPYKCEECGKAFNSRSYLTTHRRRHTGERPYKCDEC 693
Score = 32.0 bits (71), Expect = 7.9
Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 8/93 (8%)
Query: 95 QHIAANPKPTNKFFQCKFCVRYFRSKNLLIEHTRKVHGAQA-EGSSSGPPVPGS--LNYN 151
Q I KP ++CK C + FR + L +H R G + + G S L +
Sbjct: 399 QRIHTGEKP----YKCKECGKAFRCSSYLTKHKRIHTGEKPYKCKECGKAFNRSSCLTQH 454
Query: 152 IMMHEGFGKVFSCQFCTYKSPRRARIIKHQKMY 184
H G K++ C+ C+ R + +I HQ+++
Sbjct: 455 QTTHTG-EKLYKCKVCSKSYARSSNLIMHQRVH 486
>gi|22095393 zinc finger protein 420 [Homo sapiens]
Length = 688
Score = 101 bits (252), Expect = 8e-21
Identities = 137/617 (22%), Positives = 214/617 (34%), Gaps = 114/617 (18%)
Query: 1845 PFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQST 1904
P++C +C K +F A H T H S I G P Y+CK C
Sbjct: 138 PYKCKECGK-AFRRAS----HLTQHQS-------IHTGEKP------YECKQCGKAFSRD 179
Query: 1905 AELTSHLNIHNEE----FQKRAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVPKI 1960
++L+ H +H E ++ K + QL+ + G +E +
Sbjct: 180 SQLSLHQRLHTGEKPYACKECGKAFTQSSQLILHHRIHTGEKPYKCEECGKAFIRSSQLT 239
Query: 1961 KERKV----VGYKCKFCVEVHPTLRAICNHLRKHV-----QYGNVPAVSAAVKGLRSHER 2011
+ +KV Y+CK C + + H R H + V + L H+R
Sbjct: 240 RHQKVHTGEKPYECKECGKAFTQNSQLTLHQRLHTGEKLYECKECRKVFTQLSQLILHKR 299
Query: 2012 SHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKT 2071
H T E Y C+ C L +H + H+G KP+ CK C S L
Sbjct: 300 IH------TGEKPYECKECGKAFICGSQLSQHQKIHNGE-KPYECKECGRAFIRGSLLMQ 352
Query: 2072 HILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVHGKALTLPRPRIVSLLSSHSHHSSQK 2131
H + H GE YKC C + + SQL +H ++H T +P H SQ
Sbjct: 353 H-QRIHTGEKPYKCEECGKAFIRGSQLTQHQ-RIH----TNEKPYECKECGKMFSHGSQ- 405
Query: 2132 ATPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVL 2191
T + + +P ++ + +L + R+ E
Sbjct: 406 LTQHQRIHTGE-----KPYQCKECGKAFNRGSLLTRHQRI-------------HTGEKPY 447
Query: 2192 HCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDC--SFYTGFKSAFTMHVEAGHSAVPEE 2249
C+ C + + +H R H G+K ++CK+C SF G S T H
Sbjct: 448 ECKECGKTFSRGSELTQHERI-HTGEKPYECKECGKSFIRG--SQLTQHQRI------HT 498
Query: 2250 GPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVV---------- 2299
G K C C ++ H LH E+ C ++ L +
Sbjct: 499 GEKPYECKECRMAFTQSSHLSQHQRLHTGEKPYVCNECGKAFARGLLLIQHQRIHTGEKP 558
Query: 2300 FRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFEL 2359
++C +C L QH H KPY+C+ C H +L H R H + +E
Sbjct: 559 YQCKECGKAFIRGSQLTQHQRIHTGEKPYECKECGKAFSHGSQLTLHQR-IHTGEKPYE- 616
Query: 2360 VGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPCEFC 2419
+ ++ SS S H EK + C+ C
Sbjct: 617 --------CRECRKAFTQSS--------------------HLSRHQRIHTGEKPYQCKEC 648
Query: 2420 GRAFSQGSEWERHVLRH 2436
G+AF++GS+ +H H
Sbjct: 649 GKAFTRGSQLTQHQRIH 665
Score = 77.0 bits (188), Expect = 2e-13
Identities = 118/545 (21%), Positives = 193/545 (35%), Gaps = 98/545 (17%)
Query: 1845 PFRCIKCFKLSFSTAELLCMHYTDHHSR------DLKRDFIILGNGPRLQN-----STYQ 1893
P+ C +C K +F+ + L +H+ H + + FI R Q Y+
Sbjct: 194 PYACKECGK-AFTQSSQLILHHRIHTGEKPYKCEECGKAFIRSSQLTRHQKVHTGEKPYE 252
Query: 1894 CKHCDSKLQSTAELTSHLNIHNEEFQKRAKRQERRK------QLLSKQKYADGAFADFKQ 1947
CK C ++LT H +H E K + +E RK QL+ ++ G
Sbjct: 253 CKECGKAFTQNSQLTLHQRLHTGE--KLYECKECRKVFTQLSQLILHKRIHTG------- 303
Query: 1948 ERPF------------GHLEEVPKIKERKVVGYKCKFCVEVHPTLRAICNHLRKHV---Q 1992
E+P+ L + KI + Y+CK C + H R H
Sbjct: 304 EKPYECKECGKAFICGSQLSQHQKIHNGEKP-YECKECGRAFIRGSLLMQHQRIHTGEKP 362
Query: 1993 YGNVPAVSAAVKG--LRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGH 2050
Y A ++G L H+R H T E Y C+ C + + L +H + H G
Sbjct: 363 YKCEECGKAFIRGSQLTQHQRIH------TNEKPYECKECGKMFSHGSQLTQHQRIHTGE 416
Query: 2051 HKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVH---- 2106
KP++CK C + S L H + H GE Y+C C + S+L +H ++H
Sbjct: 417 -KPYQCKECGKAFNRGSLLTRH-QRIHTGEKPYECKECGKTFSRGSELTQHE-RIHTGEK 473
Query: 2107 -------GKALTLPRPRIVSLLSSHSH-HSSQKATPAEEVEDSNDSSYSEPPDVQQQLNH 2158
GK+ S L+ H H+ +K P E E + S Q+L+
Sbjct: 474 PYECKECGKSFIRG-----SQLTQHQRIHTGEK--PYECKECRMAFTQSSHLSQHQRLHT 526
Query: 2159 YQSAALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKK 2218
+ + + L E C+ C + + +H R H G+K
Sbjct: 527 GEKPYVCNECGKAFARGLLLIQHQRIHTGEKPYQCKECGKAFIRGSQLTQHQRI-HTGEK 585
Query: 2219 LFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHRE 2278
++CK+C S T+H G K C C ++ H +H
Sbjct: 586 PYECKECGKAFSHGSQLTLHQRI------HTGEKPYECRECRKAFTQSSHLSRHQRIHTG 639
Query: 2279 ERVVPIEVCRSKLSKYLQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETK 2338
E+ ++C +C + L QH H K ++ + C +
Sbjct: 640 EKP------------------YQCKECGKAFTRGSQLTQHQRIHISEKSFEYKECGIDFS 681
Query: 2339 HTEEL 2343
H ++
Sbjct: 682 HGSQV 686
Score = 74.7 bits (182), Expect = 1e-12
Identities = 93/411 (22%), Positives = 140/411 (34%), Gaps = 68/411 (16%)
Query: 2048 HGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQL--------- 2098
H KP++CK C S L H H GE Y+C C + SQL
Sbjct: 133 HSTEKPYKCKECGKAFRRASHLTQH-QSIHTGEKPYECKQCGKAFSRDSQLSLHQRLHTG 191
Query: 2099 -KEHSLKVHGKALTLPRPRIVSLLSSHSHHSSQKATPAEEVEDSNDSSYSEPPDVQQQLN 2157
K ++ K GKA T + L+ H H+ +K EE + S QL
Sbjct: 192 EKPYACKECGKAFT----QSSQLILHHRIHTGEKPYKCEECGKAFIRS--------SQLT 239
Query: 2158 HYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGK 2217
+Q ++ P Q ++ LH + H G+
Sbjct: 240 RHQKV-----HTGEKPYECKECGKAFTQNSQLTLH------------------QRLHTGE 276
Query: 2218 KLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHR 2277
KL++CK+C S +H G K C C + H +H
Sbjct: 277 KLYECKECRKVFTQLSQLILHKRI------HTGEKPYECKECGKAFICGSQLSQHQKIHN 330
Query: 2278 EERVVPIEVC-----RSKLSKYLQGV-----VFRCDKCTFTCSSDESLQQHIEKHNELKP 2327
E+ + C R L Q + ++C++C L QH H KP
Sbjct: 331 GEKPYECKECGRAFIRGSLLMQHQRIHTGEKPYKCEECGKAFIRGSQLTQHQRIHTNEKP 390
Query: 2328 YKCQLCYYETKHTEELDSHLR--DEHKVSRNFELVGRVNLDQLEQMKEKMESSSSDDEDK 2385
Y+C+ C H +L H R K + E N L +++ + E K
Sbjct: 391 YECKECGKMFSHGSQLTQHQRIHTGEKPYQCKECGKAFNRGSLLTRHQRIHTGEKPYECK 450
Query: 2386 EEEMNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRH 2436
E K R + H EK + C+ CG++F +GS+ +H H
Sbjct: 451 E---CGKTFSRG-SELTQHERIHTGEKPYECKECGKSFIRGSQLTQHQRIH 497
Score = 39.3 bits (90), Expect = 0.049
Identities = 31/125 (24%), Positives = 51/125 (40%), Gaps = 8/125 (6%)
Query: 2315 LQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFEL--VGRV-NLDQLEQM 2371
L QH H+ KPYKC+ C + L H + H + +E G+ + D +
Sbjct: 126 LSQHSRCHSTEKPYKCKECGKAFRRASHLTQH-QSIHTGEKPYECKQCGKAFSRDSQLSL 184
Query: 2372 KEKMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWER 2431
+++ + KE + ++ H EK + CE CG+AF + S+ R
Sbjct: 185 HQRLHTGEKPYACKECGKAFTQSSQLILHHRIH----TGEKPYKCEECGKAFIRSSQLTR 240
Query: 2432 HVLRH 2436
H H
Sbjct: 241 HQKVH 245
>gi|11386193 zinc finger protein 197 isoform 1 [Homo sapiens]
Length = 1029
Score = 101 bits (251), Expect = 1e-20
Identities = 134/604 (22%), Positives = 204/604 (33%), Gaps = 131/604 (21%)
Query: 1768 KCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGYFTA-VYADEHEKPTLMEEEER 1826
KC C + G++ H ++RH G P K ++ G F+ Y +H++ EE +
Sbjct: 455 KCKECGKGFYRHSGLIIH-LRRHSGERPYK--CNECGKVFSQNAYLIDHQRLHKGEEPYK 511
Query: 1827 GN-------FEKAEVEGEAQEIEWLPFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFI 1879
N +K+ + + P++C +C K +F+ L H H + +
Sbjct: 512 CNKCQKAFILKKSLILHQRIHSGEKPYKCDECGK-TFAQTTYLIDHQRLHSAEN------ 564
Query: 1880 ILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYAD 1939
Y+CK C + L H +H E+ K+ K +
Sbjct: 565 -----------PYKCKECGKVFIRSKSLLLHQRVHTEKKTFGCKK-------CGKIFSSK 606
Query: 1940 GAFADFKQERPFGHLEEVPKIKERKVVGYKCKFCVEVHPTLRAICNHLRKH-----VQYG 1994
F D K+ H E P YKC C + + +H R H +
Sbjct: 607 SNFIDHKRM----HSREKP---------YKCTECGKAFTQSAYLFDHQRLHNGEKPYECN 653
Query: 1995 NVPAVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPF 2054
V K L H+R H T E+ Y C+ C V NL H + H+G KP+
Sbjct: 654 ECGKVFILKKSLILHQRFH------TGENLYECKDCGKVFGSNRNLIDHERLHNGE-KPY 706
Query: 2055 RCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVHGKALTLPR 2114
C+ C + H K H E AYKC C GKA +
Sbjct: 707 ECRECGKTFIMSKSFMVH-QKLHTQEKAYKCEDC------------------GKAFSYNS 747
Query: 2115 PRIVSLLSSHSHHSSQKATPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNSRVSPV 2174
SLL H+ +K E A + N + +
Sbjct: 748 ----SLLVHRRIHTGEKPFECSEC----------------------GRAFSSNRNLIEHK 781
Query: 2175 PLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSA 2234
+ E C+ C +S+ H R H +K +KC DC ++S
Sbjct: 782 RIHSG--------EKPYECDECGKCFILKKSLIGHQRI-HTREKSYKCNDCGKVFSYRSN 832
Query: 2235 FTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKY 2294
H G K C C Y RN+I+H +H E+ VCR L+
Sbjct: 833 LIAHQRI------HTGEKPYACSECGKGFTYNRNLIEHQRIHSGEKTYECHVCRKVLTSS 886
Query: 2295 LQGVV----------FRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELD 2344
+V ++C++C S +++L H H KPY+C C L
Sbjct: 887 RNLMVHQRIHTGEKPYKCNECGKDFSQNKNLVVHQRMHTGEKPYECDKCRKSFTSKRNLV 946
Query: 2345 SHLR 2348
H R
Sbjct: 947 GHQR 950
Score = 84.3 bits (207), Expect = 1e-15
Identities = 118/511 (23%), Positives = 178/511 (34%), Gaps = 82/511 (16%)
Query: 1968 YKCKFCVEVHPTLRAICNHLRKHVQYGNVP-AVSAAVKGLRSHERSHLALAMFTREDKYS 2026
YKC C + + + NH R H G P KG + L + E Y
Sbjct: 370 YKCDMCCKHFNKISHLINHRRIHT--GEKPHKCKECGKGFIQRSSLLMHLRNHSGEKPYK 427
Query: 2027 CQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCS 2086
C C + L H + H G KP++CK C +S L H L+ H+GE YKC+
Sbjct: 428 CNECGKAFSQSAYLLNHQRIHTGE-KPYKCKECGKGFYRHSGLIIH-LRRHSGERPYKCN 485
Query: 2087 WCSFSTMTISQLKEHSLKVHG----------KALTLPRPRIVSLLSSHSHHSSQKATPAE 2136
C + L +H G KA L + SL+ HS +K +
Sbjct: 486 ECGKVFSQNAYLIDHQRLHKGEEPYKCNKCQKAFILKK----SLILHQRIHSGEKPYKCD 541
Query: 2137 EVEDSNDSSYSEPPDV--QQQLNHYQSAALARNNSRV---SPVPLSGAAAGTEQKTEAVL 2191
E ++++ + Q+L+ ++ + +V S L TE+KT
Sbjct: 542 EC----GKTFAQTTYLIDHQRLHSAENPYKCKECGKVFIRSKSLLLHQRVHTEKKTFGCK 597
Query: 2192 HC-EFCEFSSGYIQSIRRHYRDK-----------------------HGGKKLFKCKDCSF 2227
C + S +I R H R+K H G+K ++C +C
Sbjct: 598 KCGKIFSSKSNFIDHKRMHSREKPYKCTECGKAFTQSAYLFDHQRLHNGEKPYECNECGK 657
Query: 2228 YTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVC 2287
K + +H + H+ G C C RN+IDH LH E+
Sbjct: 658 VFILKKSLILH-QRFHT-----GENLYECKDCGKVFGSNRNLIDHERLHNGEKP------ 705
Query: 2288 RSKLSKYLQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHL 2347
+ C +C T +S H + H + K YKC+ C + L H
Sbjct: 706 ------------YECRECGKTFIMSKSFMVHQKLHTQEKAYKCEDCGKAFSYNSSLLVHR 753
Query: 2348 RDEHKVSRNFEL--VGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDRELMRFSDHG 2405
R H + FE GR ++ K S + +E + L+ H
Sbjct: 754 RI-HTGEKPFECSECGRAFSSNRNLIEHKRIHSGEKPYECDECGKCFILKKSLI---GHQ 809
Query: 2406 AALNTEKRFPCEFCGRAFSQGSEWERHVLRH 2436
EK + C CG+ FS S H H
Sbjct: 810 RIHTREKSYKCNDCGKVFSYRSNLIAHQRIH 840
Score = 58.9 bits (141), Expect = 6e-08
Identities = 145/719 (20%), Positives = 232/719 (32%), Gaps = 176/719 (24%)
Query: 1470 YQCTVCQSEYNNLHGLLTHYGKKHPGMKVKAADFAQDIDINPGAVYKCRHCPYINTRIHG 1529
Y+C +C +N + L+ H + H G K +KC+ C +
Sbjct: 370 YKCDMCCKHFNKISHLINHR-RIHTGEKP----------------HKCKECGKGFIQRSS 412
Query: 1530 VLTHYQKRHPSIKVTAEDFVHDVEQSADISQNDVEETSRIFKQGYGAYRCKLCPYTHGTL 1589
+L H + + QSA + + T G Y+CK C
Sbjct: 413 LLMHLRNHSGEKPYKCNECGKAFSQSAYLLNHQRIHT------GEKPYKCKECGKGFYRH 466
Query: 1590 EKLKIHYEKYHNQPEFDVFSQSPPKLPVPLEPEMTTEVSPSQVSITEEEV--GEEPVSTS 1647
L IH ++ + + E S + I + + GEEP +
Sbjct: 467 SGLIIHLRRHSGERPYKC-------------NECGKVFSQNAYLIDHQRLHKGEEPYKCN 513
Query: 1648 HFSTSHLVSHTV------------FRCQLC-KYFCSTRKGIARHYRIKHNNVRAQPEGKN 1694
+ ++ ++ ++C C K F T Y I H + +
Sbjct: 514 KCQKAFILKKSLILHQRIHSGEKPYKCDECGKTFAQTT------YLIDHQRLHSA----E 563
Query: 1695 NLFKCALCAYTNPIRKGLAAHYQKRHDIDAYYTHCLAASRTISDKPNKVIIPSPPKDDSP 1754
N +KC C K L H + + + C + S K N + D
Sbjct: 564 NPYKCKECGKVFIRSKSLLLHQRVHTEKKTF--GCKKCGKIFSSKSNFI-------DHKR 614
Query: 1755 QLSEELRRAVEKKKCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGYFTA----- 1809
S E + KC+ C ++F++ + + + H G K ++ G F
Sbjct: 615 MHSRE-----KPYKCTECG-KAFTQSAYLFDHQRLHNG--EKPYECNECGKVFILKKSLI 666
Query: 1810 VYADEHEKPTLMEEEERGNF---EKAEVEGEAQEIEWLPFRCIKCFKLSFSTAELLCMHY 1866
++ H L E ++ G + ++ E P+ C +C K +F ++ +H
Sbjct: 667 LHQRFHTGENLYECKDCGKVFGSNRNLIDHERLHNGEKPYECRECGK-TFIMSKSFMVHQ 725
Query: 1867 TDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHNEEFQKRAKRQE 1926
H Q Y+C+ C + L H IH E
Sbjct: 726 KLH-----------------TQEKAYKCEDCGKAFSYNSSLLVHRRIHTGEKPFECSECG 768
Query: 1927 R----RKQLLSKQKYADGAFADFKQERPFGHLEEVPK--IKERKVVG----------YKC 1970
R + L+ ++ G E+P+ +E K I ++ ++G YKC
Sbjct: 769 RAFSSNRNLIEHKRIHSG-------EKPY-ECDECGKCFILKKSLIGHQRIHTREKSYKC 820
Query: 1971 KFCVEVHPTLRAICNHLRKHVQYGNVP-AVSAAVKG------LRSHERSHLALAMFTRED 2023
C +V + H R H G P A S KG L H+R H + E
Sbjct: 821 NDCGKVFSYRSNLIAHQRIHT--GEKPYACSECGKGFTYNRNLIEHQRIH------SGEK 872
Query: 2024 KYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHIL--------- 2074
Y C C V NL H + H G KP++C C S N L H
Sbjct: 873 TYECHVCRKVLTSSRNLMVHQRIHTGE-KPYKCNECGKDFSQNKNLVVHQRMHTGEKPYE 931
Query: 2075 ------------------KAHAGEHAYKCSWCSFSTMTISQLKEHSLKVHGKALTLPRP 2115
+ H GE Y C+ CS Q K +L VH K T +P
Sbjct: 932 CDKCRKSFTSKRNLVGHQRIHTGEKPYGCNDCS---KVFRQRK--NLTVHQKIHTDEKP 985
Score = 38.5 bits (88), Expect = 0.084
Identities = 122/643 (18%), Positives = 206/643 (32%), Gaps = 144/643 (22%)
Query: 1309 EAGYHCEWCIYSHTEPNGLLLHYQRRHPEHYVDYTYMATKLWAGPDPSPPSLTMPAEAKT 1368
E Y C+ C +GL++H +R E +
Sbjct: 451 EKPYKCKECGKGFYRHSGLIIHLRRHSGE-----------------------------RP 481
Query: 1369 YRCRDC--VFEAVSIWDITNHYQAFHPWAMNGDESVLLDIIKEKDAVEKPILSSEELAGP 1426
Y+C +C VF N Y H G+E + ++ ++K ++ + +
Sbjct: 482 YKCNECGKVFSQ-------NAYLIDHQRLHKGEEPYKCNKCQKAFILKKSLILHQRIHSG 534
Query: 1427 VNCENSIPTPFPEQEAECPEDARLSPEKSLQLASANPAISSTPYQCTVCQSEYNNLHGLL 1486
E+ +C E + + + + + PY+C C + LL
Sbjct: 535 ------------EKPYKCDECGKTFAQTTYLIDHQRLHSAENPYKCKECGKVFIRSKSLL 582
Query: 1487 THYG----KKHPGMKVKAADFAQDIDI-------NPGAVYKCRHCPYINTRIHGVLTHYQ 1535
H KK G K F+ + + YKC C T+ + H +
Sbjct: 583 LHQRVHTEKKTFGCKKCGKIFSSKSNFIDHKRMHSREKPYKCTECGKAFTQSAYLFDHQR 642
Query: 1536 KRHPSIKVTAEDF--VHDVEQSADISQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLK 1593
+ + V +++S + Q F G Y CK C G+ L
Sbjct: 643 LHNGEKPYECNECGKVFILKKSLILHQR--------FHTGENLYECKDCGKVFGSNRNL- 693
Query: 1594 IHYEKYHNQPEFDVFSQSPPKLPVPLEPEMTTEVSPSQVSITEEEVGEEPVSTSHFSTSH 1653
I +E+ HN E + K + + M + +Q + E + S + H
Sbjct: 694 IDHERLHNG-EKPYECRECGKTFIMSKSFMVHQKLHTQEKAYKCEDCGKAFSYNSSLLVH 752
Query: 1654 LVSHT---VFRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCALCAYTNPIRK 1710
HT F C C S+ + + H RI H+ + ++C C ++K
Sbjct: 753 RRIHTGEKPFECSECGRAFSSNRNLIEHKRI-HSGEKP--------YECDECGKCFILKK 803
Query: 1711 GLAAHYQKRHDIDAYYTHCLAASRTISDKPNKVIIPSPPKDDSPQLSEEL-------RRA 1763
L H Q+ H + Y C + S + N + + P E R
Sbjct: 804 SLIGH-QRIHTREKSYK-CNDCGKVFSYRSNLIAHQRIHTGEKPYACSECGKGFTYNRNL 861
Query: 1764 VEKKK---------CSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGYFTAVYADE 1814
+E ++ C +C S + ++ H + H G P K ++ G F+
Sbjct: 862 IEHQRIHSGEKTYECHVCRKVLTSSRNLMVH-QRIHTGEKPYK--CNECGKDFS------ 912
Query: 1815 HEKPTLMEEEERGNFEKAEVEGEAQEIEWLPFRCIKCFKLSFSTAELLCMHYTDHHSRDL 1874
+ L+ + EK P+ C KC K SF++ L H H
Sbjct: 913 -QNKNLVVHQRMHTGEK-------------PYECDKCRK-SFTSKRNLVGHQRIH----- 952
Query: 1875 KRDFIILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHNEE 1917
G P Y C C + LT H IH +E
Sbjct: 953 ------TGEKP------YGCNDCSKVFRQRKNLTVHQKIHTDE 983
Score = 34.3 bits (77), Expect = 1.6
Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 6/83 (7%)
Query: 106 KFFQCKFCVRYFRSKNLLIEHTRKVHGAQ----AEGSSSGPPVPGSLNYNIMMHEGFGKV 161
KF++C C ++F + LI H R++H + + G SL ++ H G K
Sbjct: 368 KFYKCDMCCKHFNKISHLINH-RRIHTGEKPHKCKECGKGFIQRSSLLMHLRNHSG-EKP 425
Query: 162 FSCQFCTYKSPRRARIIKHQKMY 184
+ C C + A ++ HQ+++
Sbjct: 426 YKCNECGKAFSQSAYLLNHQRIH 448
Score = 33.5 bits (75), Expect = 2.7
Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 8/86 (9%)
Query: 599 PYKCTMCNYSTTTLKGL----RVHQQHKHSFCDNLPKFEGQPSSLPLENE--TDSHPSSS 652
PY+C C S T+ + L R+H K C++ K Q +L + + TD P
Sbjct: 929 PYECDKCRKSFTSKRNLVGHQRIHTGEKPYGCNDCSKVFRQRKNLTVHQKIHTDEKPCEC 988
Query: 653 NTVKK--SQTSILGLSSKNNFVAKAS 676
+ +K SQTS L L K + + + S
Sbjct: 989 DVSEKEFSQTSNLHLQQKIHTIEEFS 1014
>gi|38570117 zinc finger protein 569 [Homo sapiens]
Length = 686
Score = 101 bits (251), Expect = 1e-20
Identities = 119/526 (22%), Positives = 183/526 (34%), Gaps = 78/526 (14%)
Query: 1845 PFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQST 1904
P+ C C K +FS E L HY H + +Y+C C
Sbjct: 213 PYECSNCRK-AFSHKEKLIKHYKIHS-----------------REQSYKCNECGKAFIKM 254
Query: 1905 AELTSHLNIHNEEFQKRAKRQER----RKQLLSKQKYADGAFADFKQERPFGHLEEVPKI 1960
+ L H IH E K E+ + L+ +K G E ++ I
Sbjct: 255 SNLIRHQRIHTGEKPYACKECEKSFSQKSNLIDHEKIHTGEKPYECNECGKAFSQKQSLI 314
Query: 1961 KERKV----VGYKCKFCVEVHPTLRAICNHLRKHVQYGNVP-AVSAAVKGLRSHERSHLA 2015
+KV Y C C + P + ++ H+R H G P K +
Sbjct: 315 AHQKVHTGEKPYACNECGKAFPRIASLALHMRSHT--GEKPYKCDKCGKAFSQFSMLIIH 372
Query: 2016 LAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILK 2075
+ + T E Y C C + L HM++H G KP+ CK C S+ TH K
Sbjct: 373 VRIHTGEKPYECNECGKAFSQSSALTVHMRSHTG-EKPYECKECRKAFSHKKNFITH-QK 430
Query: 2076 AHAGEHAYKCSWCSFSTMTISQLKEHSLKVH-----------GKALTLPRPRIVSLLSSH 2124
H E Y+C+ C + + +S L H ++H GKA + + +L++
Sbjct: 431 IHTREKPYECNECGKAFIQMSNLVRHQ-RIHTGEKPYICKECGKAFS----QKSNLIAHE 485
Query: 2125 SHHSSQKATPAEEVED--SNDSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAAG 2182
HS +K E S ++ V Y + S+++ + L +
Sbjct: 486 KIHSGEKPYECNECGKAFSQKQNFITHQKVHTGEKPYDCNECGKAFSQIASLTLHLRSHT 545
Query: 2183 TEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAG 2242
E+ E C+ C + + H R H G+K + C +C +++ +H+ G
Sbjct: 546 GEKPYE----CDKCGKAFSQCSLLNLHMR-SHTGEKPYVCNECGKAFSQRTSLIVHMR-G 599
Query: 2243 HSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRC 2302
H+ G K C C ++ HI H E+ F C
Sbjct: 600 HT-----GEKPYECNKCGKAFSQSSSLTIHIRGHTGEK------------------PFDC 636
Query: 2303 DKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLR 2348
KC S SL H+ KH KPY C C L H R
Sbjct: 637 SKCGKAFSQISSLTLHMRKHTGEKPYHCIECGKAFSQKSHLVRHQR 682
Score = 99.8 bits (247), Expect = 3e-20
Identities = 135/573 (23%), Positives = 192/573 (33%), Gaps = 130/573 (22%)
Query: 1892 YQCKHCDSKLQSTAELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERPF 1951
++C HC T +L HL IH E K + RK K+K
Sbjct: 186 FKCNHCGKGFNQTLDLIRHLRIHTGE--KPYECSNCRKAFSHKEK--------------- 228
Query: 1952 GHLEEVPKIKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVPAVS-------AAVK 2004
L + KI R+ YKC C + + + H R H G P +
Sbjct: 229 --LIKHYKIHSRE-QSYKCNECGKAFIKMSNLIRHQRIHT--GEKPYACKECEKSFSQKS 283
Query: 2005 GLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSS 2064
L HE+ H T E Y C C + + +L H + H G KP+ C C
Sbjct: 284 NLIDHEKIH------TGEKPYECNECGKAFSQKQSLIAHQKVHTG-EKPYACNECGKAFP 336
Query: 2065 YNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVH-----------GKALTLP 2113
+ L H +++H GE YKC C + S L H +++H GKA +
Sbjct: 337 RIASLALH-MRSHTGEKPYKCDKCGKAFSQFSMLIIH-VRIHTGEKPYECNECGKAFSQS 394
Query: 2114 RPRIVSLLSSHSHHSSQKATPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNSRVSP 2173
V + S H+ +K P E E S+ + Q+++
Sbjct: 395 SALTVHMRS----HTGEK--PYECKECRKAFSHKKNFITHQKIH---------------- 432
Query: 2174 VPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKS 2233
E C C + + ++ RH R H G+K + CK+C KS
Sbjct: 433 ------------TREKPYECNECGKAFIQMSNLVRHQR-IHTGEKPYICKECGKAFSQKS 479
Query: 2234 AFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSK 2293
H E HS G K C C K+N I H +H E+ C S+
Sbjct: 480 NLIAH-EKIHS-----GEKPYECNECGKAFSQKQNFITHQKVHTGEKPYDCNECGKAFSQ 533
Query: 2294 YLQGVV----------FRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEEL 2343
+ + CDKC S L H+ H KPY C C L
Sbjct: 534 IASLTLHLRSHTGEKPYECDKCGKAFSQCSLLNLHMRSHTGEKPYVCNECGKAFSQRTSL 593
Query: 2344 DSHLRDEHKVSRNFELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDRELMRFSD 2403
H+R H + +E + + SSS +
Sbjct: 594 IVHMRG-HTGEKPYE---------CNKCGKAFSQSSS--------------------LTI 623
Query: 2404 HGAALNTEKRFPCEFCGRAFSQGSEWERHVLRH 2436
H EK F C CG+AFSQ S H+ +H
Sbjct: 624 HIRGHTGEKPFDCSKCGKAFSQISSLTLHMRKH 656
Score = 49.3 bits (116), Expect = 5e-05
Identities = 134/670 (20%), Positives = 213/670 (31%), Gaps = 186/670 (27%)
Query: 1428 NCENSIPTPFPEQEAECPEDARLSPEKSLQLASANPAISSTPYQCTVCQSEYNNLHGLLT 1487
+C N++ ++ E E P KS +S++ I TP++C C +N L+
Sbjct: 151 DCHNNVKCLMRKEHCEYNE-----PVKSYGNSSSHFVI--TPFKCNHCGKGFNQTLDLIR 203
Query: 1488 HYGKKHPGMKVKAADFAQDIDINPGAVYKCRHCPYINTRIHGVLTHYQKRHPSIKVTAED 1547
H + H G K Y+C +C + ++ HY+
Sbjct: 204 HL-RIHTGEKP----------------YECSNCRKAFSHKEKLIKHYK------------ 234
Query: 1548 FVHDVEQS--------ADISQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKY 1599
+H EQS A I +++ RI G Y CK C + L I +EK
Sbjct: 235 -IHSREQSYKCNECGKAFIKMSNLIRHQRIHT-GEKPYACKECEKSFSQKSNL-IDHEKI 291
Query: 1600 HNQPEFDVFSQSPPKLPVPLE-PEMTTEVSPSQVSITEEEV--GEEPVSTSHFSTS---- 1652
H + P E E S Q I ++V GE+P + + +
Sbjct: 292 HTGEK-------------PYECNECGKAFSQKQSLIAHQKVHTGEKPYACNECGKAFPRI 338
Query: 1653 -----HLVSHT---VFRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCALCAY 1704
H+ SHT ++C C S + H RI H + ++C C
Sbjct: 339 ASLALHMRSHTGEKPYKCDKCGKAFSQFSMLIIHVRI-HTGEKP--------YECNECGK 389
Query: 1705 TNPIRKGLAAHYQKRHDIDAYYTHCLAASRTISDKPNKVIIPSPPKDDSPQLSEELRRAV 1764
L H + Y C + S K N + +++
Sbjct: 390 AFSQSSALTVHMRSHTGEKPY--ECKECRKAFSHKKNFIT------------HQKIHTRE 435
Query: 1765 EKKKCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGYFTAVYADEHEKPTLMEEE 1824
+ +C+ C +V H + H G K + G F+ +K L+ E
Sbjct: 436 KPYECNECGKAFIQMSNLVRH-QRIHTG--EKPYICKECGKAFS-------QKSNLIAHE 485
Query: 1825 ERGNFEKAEVEGEAQEIEWLPFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNG 1884
+ + EK P+ C +C K +FS + H H G
Sbjct: 486 KIHSGEK-------------PYECNECGK-AFSQKQNFITHQKVH-----------TGEK 520
Query: 1885 PRLQNSTYQCKHCDSKLQSTAELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFAD 1944
P Y C C A LT HL H E + ++ + S+ +
Sbjct: 521 P------YDCNECGKAFSQIASLTLHLRSHTGE---KPYECDKCGKAFSQCSLLNLHMRS 571
Query: 1945 FKQERPF--------------------GHLEEVPKIKERKVVGYKCKFCVEVHPTLRAIC 1984
E+P+ GH E P Y+C C + ++
Sbjct: 572 HTGEKPYVCNECGKAFSQRTSLIVHMRGHTGEKP---------YECNKCGKAFSQSSSLT 622
Query: 1985 NHLRKHVQYGNVP-------AVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFR 2037
H+R H G P + + L H R H T E Y C C + +
Sbjct: 623 IHIRGHT--GEKPFDCSKCGKAFSQISSLTLHMRKH------TGEKPYHCIECGKAFSQK 674
Query: 2038 HNLDRHMQTH 2047
+L RH + H
Sbjct: 675 SHLVRHQRIH 684
Score = 35.4 bits (80), Expect = 0.71
Identities = 52/236 (22%), Positives = 89/236 (37%), Gaps = 46/236 (19%)
Query: 733 EIEVELDREEEPTEPIIEVPTSFSAQQIWVRDTSEPQKEPNFRNITHDYNAT----NGAE 788
++ +L++EEEP EV +IW D + ++ R + + T G E
Sbjct: 55 DVIFKLEQEEEPWVMEEEVLRRHWQGEIWGVDEHQKNQDRLLRQVEVKFQKTLTEEKGNE 114
Query: 789 IELTLSED---EEDYYGSSTNLKDHQVSNTALLNTQTPIYGTEHNSENTDFGDSGRLYYC 845
+ + D++ S NL ++ + L EHN + + + L
Sbjct: 115 CQKKFANVFPLNSDFFPSRHNLYEYDLFGKCL----------EHNFDCHN--NVKCLMRK 162
Query: 846 KHCDFN-------NKSARSVSTHYQRMHPYIKFSFRYILDPNDHSAV------YRCLECY 892
+HC++N N S+ V T ++ H F LD H + Y C C
Sbjct: 163 EHCEYNEPVKSYGNSSSHFVITPFKCNH--CGKGFNQTLDLIRHLRIHTGEKPYECSNCR 220
Query: 893 IDYTNFEDLQQHYGEHHPEAMNVLNFDHSDLIYRCRFCSYTSPNVRSLMPHYQRMH 948
+++ E L +HY H E Y+C C + +L+ H QR+H
Sbjct: 221 KAFSHKEKLIKHYKIHSREQS-----------YKCNECGKAFIKMSNLIRH-QRIH 264
>gi|68303809 zinc finger protein 43 [Homo sapiens]
Length = 809
Score = 100 bits (250), Expect = 1e-20
Identities = 136/590 (23%), Positives = 217/590 (36%), Gaps = 116/590 (19%)
Query: 1892 YQCKHCDSKLQSTAELTSHLNIHN-EEFQKR---AKRQERRKQLLSKQKYADGAFADFKQ 1947
Y+C+ C ++ LT+H I E+F K AK + L +K G
Sbjct: 258 YKCEECGKAFNKSSILTTHKIIRTGEKFYKCKECAKAFNQSSNLTEHKKIHPG------- 310
Query: 1948 ERPFGHLEEVPKIKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVPAVSAAV---- 2003
E+P YKC+ C + + H R H G P
Sbjct: 311 EKP-----------------YKCEECGKAFNWPSTLTKHKRIHT--GEKPYTCEECGKAF 351
Query: 2004 ---KGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCS 2060
L +H+R H T E Y C C + NL +H + H KP++C+ C
Sbjct: 352 NQFSNLTTHKRIH------TAEKFYKCTECGEAFSRSSNLTKHKKIHT-EKKPYKCEECG 404
Query: 2061 FKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHS----------LKVHGKAL 2110
++S+L H L H GE YKC C + S L +H+ +V GKA
Sbjct: 405 KAFKWSSKLTEHKL-THTGEKPYKCEECGKAFNWPSTLTKHNRIHTGEKPYKCEVCGKAF 463
Query: 2111 TLPRPRIVSLLSSHSH-HSSQKATPAEEVED--SNDSSYSEPPDVQQQLNHYQSAALARN 2167
S L++H H+++K EE S S+ ++ + + Y+ +
Sbjct: 464 NQ-----FSNLTTHKRIHTAEKPYKCEECGKAFSRSSNLTKHKKIHIEKKPYKCEECGKA 518
Query: 2168 NSRVSPVPLSGAAAGTEQKT----EAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCK 2223
S + TE K E CE C + + + +H R H G+K +KC+
Sbjct: 519 FKWSSKL--------TEHKITHTGEKPYKCEECGKAFNHFSILTKHKRI-HTGEKPYKCE 569
Query: 2224 DCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVP 2283
+C S T H + G K +C C N+ H +H +
Sbjct: 570 ECGKAFTQSSNLTTHKKI------HTGEKFYKCEECGKAFTQSSNLTTHKKIHTGGKPYK 623
Query: 2284 IEVCRSKLSKY----------LQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLC 2333
E C +++ + ++C++C +L +H H KPYKC+ C
Sbjct: 624 CEECGKAFNQFSTLTKHKIIHTEEKPYKCEECGKAFKWSSTLTKHKIIHTGEKPYKCEEC 683
Query: 2334 YYETKHTEELDSHLRDEHKVSRNFELVGRVNLDQLEQMKEKMESSSSDDEDKE----EEM 2389
K + L +H + H + ++ E+ + SS+ E K+ E+
Sbjct: 684 GKAFKLSSTLSTH-KIIHTGEKPYKC---------EKCGKAFNRSSNLIEHKKIHTGEQP 733
Query: 2390 NSKAEDRELMRFSDHGAALNTEKR-------FPCEFCGRAFSQGSEWERH 2432
E + +S H LNT KR + C+ CG+AF+Q S H
Sbjct: 734 YKCEECGKAFNYSSH---LNTHKRIHTKEQPYKCKECGKAFNQYSNLTTH 780
Score = 92.0 bits (227), Expect = 6e-18
Identities = 118/539 (21%), Positives = 192/539 (35%), Gaps = 92/539 (17%)
Query: 1959 KIKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYG-----------NVPAVSAAVKGLR 2007
KI + +KCK C + L + H H + N P++ +
Sbjct: 165 KISHTEKKLFKCKECGKSFCMLPHLAQHKIIHTRVNFCKCEKCGKAFNCPSI------IT 218
Query: 2008 SHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNS 2067
H+R + T E Y+C+ C V + L H + ++ +K ++C+ C + +S
Sbjct: 219 KHKRIN------TGEKPYTCEECGKVFNWSSRLTTHKK-NYTRYKLYKCEECGKAFNKSS 271
Query: 2068 RLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVH-----------GKALTLPRPR 2116
L TH + GE YKC C+ + S L EH K+H GKA P
Sbjct: 272 ILTTHKI-IRTGEKFYKCKECAKAFNQSSNLTEHK-KIHPGEKPYKCEECGKAFNWP--- 326
Query: 2117 IVSLLSSHSH-HSSQKATPAEEVEDSND--SSYSEPPDVQQQLNHYQSAALARNNSRVSP 2173
S L+ H H+ +K EE + + S+ + + Y+ SR S
Sbjct: 327 --STLTKHKRIHTGEKPYTCEECGKAFNQFSNLTTHKRIHTAEKFYKCTECGEAFSRSSN 384
Query: 2174 VPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKS 2233
+ TE+K CE C + + + H + H G+K +KC++C + S
Sbjct: 385 LT-KHKKIHTEKKP---YKCEECGKAFKWSSKLTEH-KLTHTGEKPYKCEECGKAFNWPS 439
Query: 2234 AFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSK 2293
T H G K +C +C N+ H +H E+ E C S+
Sbjct: 440 TLTKHNRI------HTGEKPYKCEVCGKAFNQFSNLTTHKRIHTAEKPYKCEECGKAFSR 493
Query: 2294 ----------YLQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEEL 2343
+++ ++C++C L +H H KPYKC+ C H L
Sbjct: 494 SSNLTKHKKIHIEKKPYKCEECGKAFKWSSKLTEHKITHTGEKPYKCEECGKAFNHFSIL 553
Query: 2344 DSHLR--------------DEHKVSRNFELVGRVNLDQ----LEQMKEKMESSSSDDEDK 2385
H R S N +++ + E+ + SS+ K
Sbjct: 554 TKHKRIHTGEKPYKCEECGKAFTQSSNLTTHKKIHTGEKFYKCEECGKAFTQSSNLTTHK 613
Query: 2386 EEEMNSKAEDRE--------LMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRH 2436
+ K E + H EK + CE CG+AF S +H + H
Sbjct: 614 KIHTGGKPYKCEECGKAFNQFSTLTKHKIIHTEEKPYKCEECGKAFKWSSTLTKHKIIH 672
Score = 75.1 bits (183), Expect = 8e-13
Identities = 149/682 (21%), Positives = 240/682 (35%), Gaps = 141/682 (20%)
Query: 1469 PYQCTVCQSEYNNLHGLLTHYGKKHPGMKV-----------KAADFAQDIDINPGA-VYK 1516
PY C C +N L TH K + K+ K++ I G YK
Sbjct: 229 PYTCEECGKVFNWSSRLTTHK-KNYTRYKLYKCEECGKAFNKSSILTTHKIIRTGEKFYK 287
Query: 1517 CRHCPYINTRIHGVLTHYQKRHPSIK-VTAEDFVHDVEQSADISQNDVEETSRIFKQGYG 1575
C+ C + LT ++K HP K E+ + ++++ T G
Sbjct: 288 CKECAKAFNQSSN-LTEHKKIHPGEKPYKCEECGKAFNWPSTLTKHKRIHT------GEK 340
Query: 1576 AYRCKLCPYTHGTLEKLKIHYEKYHNQPEF-------DVFSQSPPKLPVPLEPEMTTEVS 1628
Y C+ C L H ++ H +F + FS+S + ++ TE
Sbjct: 341 PYTCEECGKAFNQFSNLTTH-KRIHTAEKFYKCTECGEAFSRSSN---LTKHKKIHTEKK 396
Query: 1629 PSQVSITEEEVGEEPVSTSHFSTSHLVSHT---VFRCQLCKYFCSTRKGIARHYRIKHNN 1685
P + EE G+ +S T H ++HT ++C+ C + + +H RI H
Sbjct: 397 PYKC----EECGKAFKWSSKL-TEHKLTHTGEKPYKCEECGKAFNWPSTLTKHNRI-HTG 450
Query: 1686 VRAQPEGKNNLFKCALCAYTNPIRKGLAAHYQKRHDIDAYYTHCLAASRTISDKPNKVII 1745
+ +KC +C L H ++ H + Y C + S N
Sbjct: 451 EKP--------YKCEVCGKAFNQFSNLTTH-KRIHTAEKPYK-CEECGKAFSRSSN---- 496
Query: 1746 PSPPKDDSPQLSEELRRAVEKK--KCSLCSFQSFSKKGIVSHYMKRHPGVFPKK-QHASK 1802
L++ + +EKK KC C ++F ++ + H G P K + K
Sbjct: 497 ----------LTKHKKIHIEKKPYKCEECG-KAFKWSSKLTEHKITHTGEKPYKCEECGK 545
Query: 1803 LGGYFTAVYADEHEKPTLMEEEERGNFEKAEVEGEAQEIEWLPFRCIKCFKLSFSTAELL 1862
+F+ + +H++ E+ P++C +C K +F+ + L
Sbjct: 546 AFNHFSIL--TKHKRIHTGEK---------------------PYKCEECGK-AFTQSSNL 581
Query: 1863 CMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHNEEFQKRA 1922
H H Y+C+ C ++ LT+H IH K
Sbjct: 582 TTHKKIHTGEKF-----------------YKCEECGKAFTQSSNLTTHKKIHTGG--KPY 622
Query: 1923 KRQERRKQLLSKQKYADGAFADFKQ--ERPFGHLEEVPKIKERKVVGYKCKFCVEVHPTL 1980
K +E K AF F + H EE P YKC+ C +
Sbjct: 623 KCEECGK-----------AFNQFSTLTKHKIIHTEEKP---------YKCEECGKAFKWS 662
Query: 1981 RAICNHLRKHVQYGNVP-AVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHN 2039
+ H K + G P K + + T E Y C+ C N
Sbjct: 663 STLTKH--KIIHTGEKPYKCEECGKAFKLSSTLSTHKIIHTGEKPYKCEKCGKAFNRSSN 720
Query: 2040 LDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLK 2099
L H + H G +P++C+ C +Y+S L TH + H E YKC C + S L
Sbjct: 721 LIEHKKIHTGE-QPYKCEECGKAFNYSSHLNTH-KRIHTKEQPYKCKECGKAFNQYSNLT 778
Query: 2100 EHSLKVH-GKALTLPRPRIVSL 2120
H+ K+H G+ L P V L
Sbjct: 779 THN-KIHTGEKLYKPEDVTVIL 799
Score = 45.8 bits (107), Expect = 5e-04
Identities = 57/274 (20%), Positives = 89/274 (32%), Gaps = 64/274 (23%)
Query: 2210 YRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVP--------EEGPKDLRCPLCLY 2261
++ H KKLFKCK+C KS + A H + E+ K CP +
Sbjct: 164 HKISHTEKKLFKCKECG-----KSFCMLPHLAQHKIIHTRVNFCKCEKCGKAFNCPSII- 217
Query: 2262 HTKYKR-----------------NMIDHIVLHREE----RVVPIEVCRSKLSK------- 2293
TK+KR N + H++ ++ E C +K
Sbjct: 218 -TKHKRINTGEKPYTCEECGKVFNWSSRLTTHKKNYTRYKLYKCEECGKAFNKSSILTTH 276
Query: 2294 ---YLQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDE 2350
++C +C + +L +H + H KPYKC+ C L H R
Sbjct: 277 KIIRTGEKFYKCKECAKAFNQSSNLTEHKKIHPGEKPYKCEECGKAFNWPSTLTKHKRIH 336
Query: 2351 --------HKVSRNFELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDRELMRFS 2402
+ + F + + EK + E N +
Sbjct: 337 TGEKPYTCEECGKAFNQFSNLTTHKRIHTAEKFYKCTECGEAFSRSSN----------LT 386
Query: 2403 DHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRH 2436
H +K + CE CG+AF S+ H L H
Sbjct: 387 KHKKIHTEKKPYKCEECGKAFKWSSKLTEHKLTH 420
Score = 36.6 bits (83), Expect = 0.32
Identities = 41/180 (22%), Positives = 64/180 (35%), Gaps = 30/180 (16%)
Query: 2296 QGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSR 2355
Q +F DKC + +H H E K +KC+ C L +HK+
Sbjct: 142 QSKIFLFDKCVKAFHKFSNSNRHKISHTEKKLFKCKECGKSFCMLPHL-----AQHKIIH 196
Query: 2356 NFELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDRE--------LMRFSDHGAA 2407
RVN + E+ + S + K K E R + H
Sbjct: 197 T-----RVNFCKCEKCGKAFNCPSIITKHKRINTGEKPYTCEECGKVFNWSSRLTTHKKN 251
Query: 2408 LNTEKRFPCEFCGRAFSQGSEWERH-VLRHGMALNDTKQVSR-----------EEIHPKE 2455
K + CE CG+AF++ S H ++R G K+ ++ ++IHP E
Sbjct: 252 YTRYKLYKCEECGKAFNKSSILTTHKIIRTGEKFYKCKECAKAFNQSSNLTEHKKIHPGE 311
Score = 35.8 bits (81), Expect = 0.54
Identities = 20/56 (35%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C ++++H + IH+ K YKC+EC K S KL HK HTG
Sbjct: 482 YKCEECGKAFSRSSNLTKH-KKIHIEKKP--YKCEECGKAFKWSSKLTEHKITHTG 534
Score = 35.0 bits (79), Expect = 0.93
Identities = 20/56 (35%), Positives = 28/56 (50%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C ++++H + IH K YKC+EC K S KL HK HTG
Sbjct: 370 YKCTECGEAFSRSSNLTKH-KKIHTEKKP--YKCEECGKAFKWSSKLTEHKLTHTG 422
Score = 34.3 bits (77), Expect = 1.6
Identities = 19/56 (33%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C H +++H + IH K YKC+EC S L HK+ HTG
Sbjct: 538 YKCEECGKAFNHFSILTKH-KRIHTGEKP--YKCEECGKAFTQSSNLTTHKKIHTG 590
Score = 33.1 bits (74), Expect = 3.5
Identities = 20/83 (24%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 106 KFFQCKFCVRYFRSKNLLIEHTRKVHGAQ----AEGSSSGPPVPGSLNYNIMMHEGFGKV 161
KF++CK C + F + L EH +K+H + E P +L + +H G K
Sbjct: 284 KFYKCKECAKAFNQSSNLTEH-KKIHPGEKPYKCEECGKAFNWPSTLTKHKRIHTG-EKP 341
Query: 162 FSCQFCTYKSPRRARIIKHQKMY 184
++C+ C + + + H++++
Sbjct: 342 YTCEECGKAFNQFSNLTTHKRIH 364
Score = 32.3 bits (72), Expect = 6.0
Identities = 18/56 (32%), Positives = 26/56 (46%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C +++ H + IH K YKC+EC S L HK+ HTG
Sbjct: 566 YKCEECGKAFTQSSNLTTH-KKIHTGEK--FYKCEECGKAFTQSSNLTTHKKIHTG 618
Score = 32.3 bits (72), Expect = 6.0
Identities = 22/73 (30%), Positives = 34/73 (46%), Gaps = 10/73 (13%)
Query: 422 NKLLETKGIPFRRFMNRFQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKS 481
+K++ T+ P++ C C ++++H + IH K YKC+EC K
Sbjct: 640 HKIIHTEEKPYK-------CEECGKAFKWSSTLTKH-KIIHTGEKP--YKCEECGKAFKL 689
Query: 482 SLKLGAHKQCHTG 494
S L HK HTG
Sbjct: 690 SSTLSTHKIIHTG 702
>gi|209954795 zinc finger protein 761 [Homo sapiens]
Length = 746
Score = 100 bits (248), Expect = 2e-20
Identities = 121/500 (24%), Positives = 184/500 (36%), Gaps = 60/500 (12%)
Query: 1968 YKCKFCVEVHPTLRAICNHLRKHV-----QYGNVPAVSAAVKGLRSHERSHLALAMFTRE 2022
YKC C ++ R + H R H + + L H R H T E
Sbjct: 242 YKCDVCGKLFNQKRNLACHRRCHTGENPYKCNECGKTFSQTSSLTCHRRLH------TGE 295
Query: 2023 DKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHA 2082
Y C+ C F+ L+RH + H KP++C C S L H + H GE
Sbjct: 296 KPYKCEECDKAFHFKSILERH-RIIHTEEKPYKCNECGKTFRQKSILTRHH-RLHTGEKP 353
Query: 2083 YKCSWCSFSTMTISQLKEHSLKVHGKALTLPRPRIV----------SLLSSHSH-HSSQK 2131
YKC+ C T S + SL H + T +P S L+ H H+ +K
Sbjct: 354 YKCNECG---KTFSH--KSSLTCHHRLHTGEKPYKCNECGKTFSHKSSLTCHRRLHTGEK 408
Query: 2132 ATPAEEVEDSND--SSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEA 2189
EE + + S++ + + N Y+ + SR S + EQ +
Sbjct: 409 PYKCEECDKAYSFRSNFEIHRKIHTEDNAYKCNECGKTFSRTSSLTCHRRRHTGEQPYK- 467
Query: 2190 VLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEE 2249
CE C+ + + ++ RH R H G+K +KC +C KS T H
Sbjct: 468 ---CEECDKAFRFKSNLERHRRI-HTGEKPYKCNECGKTFSRKSYLTCHHRL------HT 517
Query: 2250 GPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQ----------GVV 2299
G K +C C +K ++ H LH E+ + C ++ L
Sbjct: 518 GEKAYKCNECGKTFSWKSSLTCHRRLHSGEKPYKCKECGKTFNQQLTLKRHRRLHSGENP 577
Query: 2300 FRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFEL 2359
++C+ S +L+ H + H E PYKC C T L H R H + ++
Sbjct: 578 YKCEDSDKAYSFKSNLEIHQKIHTEENPYKCNECGKTFSRTSSLTCHRR-LHTGEKPYKC 636
Query: 2360 VGRVNLDQLEQMKEKMESSSS-DDEDKEEEMNS--KAEDRELMRFSDHGAALNTEKRFPC 2416
D+ ++K +E +K + N K R+ F H EK + C
Sbjct: 637 E---ECDKAFRVKSNLEGHRRIHTGEKPYKCNECGKTFSRKSY-FICHHRLHTGEKPYKC 692
Query: 2417 EFCGRAFSQGSEWERHVLRH 2436
CG+ FSQ S H H
Sbjct: 693 NECGKNFSQKSSLICHHRLH 712
Score = 93.2 bits (230), Expect = 3e-18
Identities = 121/550 (22%), Positives = 181/550 (32%), Gaps = 84/550 (15%)
Query: 1892 YQCKHCDSKLQSTAELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERPF 1951
Y+C C T+ LT H +H E K K +E K F +
Sbjct: 270 YKCNECGKTFSQTSSLTCHRRLHTGE--KPYKCEECDKAF---------HFKSILERHRI 318
Query: 1952 GHLEEVPKIKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVPAVSAAVKGLRSHER 2011
H EE P YKC C + + H R H G P SH+
Sbjct: 319 IHTEEKP---------YKCNECGKTFRQKSILTRHHRLHT--GEKPYKCNECGKTFSHKS 367
Query: 2012 SHLA-LAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLK 2070
S + T E Y C C + + +L H + H G KP++C+ C S+ S +
Sbjct: 368 SLTCHHRLHTGEKPYKCNECGKTFSHKSSLTCHRRLHTG-EKPYKCEECDKAYSFRSNFE 426
Query: 2071 THILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVHGKALTLPRPRIVSLLSSHSHHSSQ 2130
H K H ++AYKC+ C GK + R SL H+ +
Sbjct: 427 IH-RKIHTEDNAYKCNEC------------------GKTFS----RTSSLTCHRRRHTGE 463
Query: 2131 KATPAEEVEDS--NDSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTE 2188
+ EE + + S+ + Y+ + SR S + E
Sbjct: 464 QPYKCEECDKAFRFKSNLERHRRIHTGEKPYKCNECGKTFSRKSYLTCHHRL----HTGE 519
Query: 2189 AVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPE 2248
C C + + S+ H R H G+K +KCK+C F +
Sbjct: 520 KAYKCNECGKTFSWKSSLTCH-RRLHSGEKPYKCKECG------KTFNQQLTLKRHRRLH 572
Query: 2249 EGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRCDKCTFT 2308
G +C +K N+ H +H EE ++C++C T
Sbjct: 573 SGENPYKCEDSDKAYSFKSNLEIHQKIHTEEN------------------PYKCNECGKT 614
Query: 2309 CSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLR--DEHKVSRNFELVGRVNLD 2366
S SL H H KPYKC+ C + L+ H R K + E +
Sbjct: 615 FSRTSSLTCHRRLHTGEKPYKCEECDKAFRVKSNLEGHRRIHTGEKPYKCNECGKTFSRK 674
Query: 2367 QLEQMKEKMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQG 2426
++ + + E N + + H EK + C CG+ FSQ
Sbjct: 675 SYFICHHRLHTGEKPYKCNECGKNFSQKSSLICHHRLH----TGEKPYKCNECGKTFSQK 730
Query: 2427 SEWERHVLRH 2436
S H H
Sbjct: 731 SNLTCHRRLH 740
Score = 87.0 bits (214), Expect = 2e-16
Identities = 113/484 (23%), Positives = 175/484 (36%), Gaps = 64/484 (13%)
Query: 1975 EVHPTLRAI-CNHLRKHVQYGNVPAVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFV 2033
EVH ++ CN K Y ++ LR H+ HLA DKY C C +
Sbjct: 207 EVHMREKSFQCNESGKAFNYSSL---------LRKHQIIHLA-------DKYKCDVCGKL 250
Query: 2034 SAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTM 2093
+ NL H + H G + P++C C S S L H + H GE YKC C +
Sbjct: 251 FNQKRNLACHRRCHTGEN-PYKCNECGKTFSQTSSLTCH-RRLHTGEKPYKCEECDKAFH 308
Query: 2094 TISQLKEHSLKVHGKALTLPRP----------RIVSLLSSHSH-HSSQKATPAEEVED-- 2140
S L+ H + +H T +P R S+L+ H H+ +K E
Sbjct: 309 FKSILERHRI-IH----TEEKPYKCNECGKTFRQKSILTRHHRLHTGEKPYKCNECGKTF 363
Query: 2141 SNDSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSS 2200
S+ SS + + Y+ + S S + E+ + CE C+ +
Sbjct: 364 SHKSSLTCHHRLHTGEKPYKCNECGKTFSHKSSLTCHRRLHTGEKPYK----CEECDKAY 419
Query: 2201 GYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCL 2260
+ + H R H +KC +C S+ T H G + +C C
Sbjct: 420 SFRSNFEIH-RKIHTEDNAYKCNECGKTFSRTSSLTCHRRR------HTGEQPYKCEECD 472
Query: 2261 YHTKYKRNMIDHIVLHREERVVPIEVCRSKLSK----------YLQGVVFRCDKCTFTCS 2310
++K N+ H +H E+ C S+ + ++C++C T S
Sbjct: 473 KAFRFKSNLERHRRIHTGEKPYKCNECGKTFSRKSYLTCHHRLHTGEKAYKCNECGKTFS 532
Query: 2311 SDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFELVGRVNLDQLEQ 2370
SL H H+ KPYKC+ C L H R H ++ + D+
Sbjct: 533 WKSSLTCHRRLHSGEKPYKCKECGKTFNQQLTLKRH-RRLHSGENPYKC---EDSDKAYS 588
Query: 2371 MKEKME-SSSSDDEDKEEEMNSKAED-RELMRFSDHGAALNTEKRFPCEFCGRAFSQGSE 2428
K +E E+ + N + + H EK + CE C +AF S
Sbjct: 589 FKSNLEIHQKIHTEENPYKCNECGKTFSRTSSLTCHRRLHTGEKPYKCEECDKAFRVKSN 648
Query: 2429 WERH 2432
E H
Sbjct: 649 LEGH 652
Score = 70.5 bits (171), Expect = 2e-11
Identities = 112/509 (22%), Positives = 173/509 (33%), Gaps = 121/509 (23%)
Query: 1641 EEPVSTSHFST---SHLVSHTV---FRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKN 1694
EE HF + H + HT ++C C + + RH+R+ H +
Sbjct: 301 EECDKAFHFKSILERHRIIHTEEKPYKCNECGKTFRQKSILTRHHRL-HTGEKP------ 353
Query: 1695 NLFKCALCAYTNPIRKGLAAHYQKRHDIDAYYTHCLAASRTISDKPNKVIIPSPPKDDSP 1754
+KC C T + L H++ Y C +T S K + + P
Sbjct: 354 --YKCNECGKTFSHKSSLTCHHRLHTGEKPY--KCNECGKTFSHKSSLTCHRRLHTGEKP 409
Query: 1755 QLSEELRRA--------VEKK--------KCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQ 1798
EE +A + +K KC+ C ++FS+ ++ + +RH G
Sbjct: 410 YKCEECDKAYSFRSNFEIHRKIHTEDNAYKCNECG-KTFSRTSSLTCHRRRHTG------ 462
Query: 1799 HASKLGGYFTAVYADEHEKPTLMEEEERGNFEKAEVEGEAQ-EIEWLPFRCIKCFKLSFS 1857
E+P EE ++ K+ +E + P++C +C K +FS
Sbjct: 463 -----------------EQPYKCEECDKAFRFKSNLERHRRIHTGEKPYKCNECGK-TFS 504
Query: 1858 TAELLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHNEE 1917
L H+ H Y+C C + LT H +H+ E
Sbjct: 505 RKSYLTCHHRLHTGE-----------------KAYKCNECGKTFSWKSSLTCHRRLHSGE 547
Query: 1918 FQKRAKR----------QERRKQLLS-----KQKYADGAFADFKQERPFG---HLEEVPK 1959
+ K +R ++L S K + +D A++ FK H EE P
Sbjct: 548 KPYKCKECGKTFNQQLTLKRHRRLHSGENPYKCEDSDKAYS-FKSNLEIHQKIHTEENP- 605
Query: 1960 IKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVP-------AVSAAVKGLRSHERS 2012
YKC C + ++ H R H G P L H R
Sbjct: 606 --------YKCNECGKTFSRTSSLTCHRRLHT--GEKPYKCEECDKAFRVKSNLEGHRRI 655
Query: 2013 HLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTH 2072
H T E Y C C + + H + H G KP++C C S S L H
Sbjct: 656 H------TGEKPYKCNECGKTFSRKSYFICHHRLHTGE-KPYKCNECGKNFSQKSSLICH 708
Query: 2073 ILKAHAGEHAYKCSWCSFSTMTISQLKEH 2101
+ H GE YKC+ C + S L H
Sbjct: 709 H-RLHTGEKPYKCNECGKTFSQKSNLTCH 736
Score = 66.2 bits (160), Expect = 4e-10
Identities = 119/590 (20%), Positives = 196/590 (33%), Gaps = 143/590 (24%)
Query: 1697 FKCALCAYTNPIRKGLAAHYQKRHDIDAYYTHCLAASRTISDKPNKVIIPSPPKDDSPQL 1756
+KC +C ++ LA H + + Y C +T S + + P
Sbjct: 242 YKCDVCGKLFNQKRNLACHRRCHTGENPY--KCNECGKTFSQTSSLTCHRRLHTGEKPYK 299
Query: 1757 SEELRRAVEKK----------------KCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHA 1800
EE +A K KC+ C ++F +K I++ + + H G P K
Sbjct: 300 CEECDKAFHFKSILERHRIIHTEEKPYKCNECG-KTFRQKSILTRHHRLHTGEKPYK--C 356
Query: 1801 SKLGGYFTAVYADEHEKPTLMEEEERGNFEKAEVEGEAQEIEWLPFRCIKCFKLSFSTAE 1860
++ G F+ K +L EK P++C +C K +
Sbjct: 357 NECGKTFS-------HKSSLTCHHRLHTGEK-------------PYKCNECGKTFSHKSS 396
Query: 1861 LLCMHYTDHHSRDLK----------RDFIILGNGPRLQNSTYQCKHCDSKLQSTAELTSH 1910
L C + K R + +++ Y+C C T+ LT H
Sbjct: 397 LTCHRRLHTGEKPYKCEECDKAYSFRSNFEIHRKIHTEDNAYKCNECGKTFSRTSSLTCH 456
Query: 1911 LNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVPKIKERKVVGYKC 1970
H E + + ++ + S + ++ R H E P YKC
Sbjct: 457 RRRHTGEQPYKCEECDKAFRFKS----------NLERHRRI-HTGEKP---------YKC 496
Query: 1971 KFCVEVHPTLRAICNHLRKHVQYGNVPAVSAAVKGLRSHERSHLALAMFTREDKYSCQYC 2030
C + + H R H T E Y C C
Sbjct: 497 NECGKTFSRKSYLTCHHRLH-----------------------------TGEKAYKCNEC 527
Query: 2031 SFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSF 2090
+++ +L H + H G KP++CK C + LK H + H+GE+ YKC
Sbjct: 528 GKTFSWKSSLTCHRRLHSG-EKPYKCKECGKTFNQQLTLKRH-RRLHSGENPYKCEDSDK 585
Query: 2091 STMTISQLKEHSLKVH-----------GKALTLPRPRIVSLLSSHSHHSSQKATPAEEVE 2139
+ S L+ H K+H GK + R SL H+ +K EE
Sbjct: 586 AYSFKSNLEIHQ-KIHTEENPYKCNECGKTFS----RTSSLTCHRRLHTGEKPYKCEEC- 639
Query: 2140 DSNDSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVLH------- 2192
D ++ V+ L ++ R ++ P + +K+ + H
Sbjct: 640 ---DKAFR----VKSNLEGHR-----RIHTGEKPYKCNECGKTFSRKSYFICHHRLHTGE 687
Query: 2193 ----CEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMH 2238
C C + S+ H+R H G+K +KC +C KS T H
Sbjct: 688 KPYKCNECGKNFSQKSSLICHHR-LHTGEKPYKCNECGKTFSQKSNLTCH 736
Score = 50.8 bits (120), Expect = 2e-05
Identities = 95/496 (19%), Positives = 160/496 (32%), Gaps = 88/496 (17%)
Query: 1439 EQEAECPEDARLSPEKSLQLASANPAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPGMKV 1498
E+ +C E + +KS+ PY+C C +++ L H+ + H G K
Sbjct: 323 EKPYKCNECGKTFRQKSILTRHHRLHTGEKPYKCNECGKTFSHKSSLTCHH-RLHTGEKP 381
Query: 1499 KAADFAQDIDINPGAVYKCRHCPYINTRIH-GVLTHYQKRHPSIKVTAEDFVHDVEQSAD 1557
YKC C T H LT +++ H T E E
Sbjct: 382 ----------------YKCNECG--KTFSHKSSLTCHRRLH-----TGEKPYKCEECDKA 418
Query: 1558 ISQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFDVFSQSPPKLPV 1617
S E R AY+C C T L H ++ + + +
Sbjct: 419 YSFRSNFEIHRKIHTEDNAYKCNECGKTFSRTSSLTCHRRRHTGEQPYKC-EECDKAFRF 477
Query: 1618 PLEPEMTTEVSPSQVSITEEEVGEEPVSTSHFSTSHLVSHT---VFRCQLCKYFCSTRKG 1674
E + + E G+ S + T H HT ++C C S +
Sbjct: 478 KSNLERHRRIHTGEKPYKCNECGKT-FSRKSYLTCHHRLHTGEKAYKCNECGKTFSWKSS 536
Query: 1675 IARHYRIKHNNVRAQPEGKNNLFKCALCAYTNPIRKGLAAHYQKRHDIDAYYTHCLAASR 1734
+ H R+ H+ + +KC C T + L H + + Y C + +
Sbjct: 537 LTCHRRL-HSGEKP--------YKCKECGKTFNQQLTLKRHRRLHSGENPY--KCEDSDK 585
Query: 1735 TISDKPNKVIIPSPPKDDSPQLSEELRRAVEKKKCSLCSFQSFSKKGIVSHYMKRHPGVF 1794
S K N I +++P KC+ C ++FS+ ++ + + H G
Sbjct: 586 AYSFKSNLEIHQKIHTEENPY------------KCNECG-KTFSRTSSLTCHRRLHTG-- 630
Query: 1795 PKKQHASKLGGYFTAVYADEHEKPTLMEEEERGNFEKAEVEGEAQ-EIEWLPFRCIKCFK 1853
EKP EE ++ K+ +EG + P++C +C K
Sbjct: 631 ---------------------EKPYKCEECDKAFRVKSNLEGHRRIHTGEKPYKCNECGK 669
Query: 1854 LSFSTAELLCMHYTDHHSRDLK----------RDFIILGNGPRLQNSTYQCKHCDSKLQS 1903
+ +C H + K + +I + Y+C C
Sbjct: 670 TFSRKSYFICHHRLHTGEKPYKCNECGKNFSQKSSLICHHRLHTGEKPYKCNECGKTFSQ 729
Query: 1904 TAELTSHLNIHNEEFQ 1919
+ LT H +H E Q
Sbjct: 730 KSNLTCHRRLHTGEKQ 745
Score = 47.0 bits (110), Expect = 2e-04
Identities = 127/612 (20%), Positives = 194/612 (31%), Gaps = 143/612 (23%)
Query: 1470 YQCTVCQSEYNNLHGLLTHYGKKHPGMKVKAADFAQDIDINPGAVYKCRHCPYINTRIHG 1529
Y+C VC +N L H + H G NP YKC C ++
Sbjct: 242 YKCDVCGKLFNQKRNLACH-RRCHTGE-------------NP---YKCNECGKTFSQTSS 284
Query: 1530 VLTHYQKRHPSIKVTAEDFVHDVEQSADISQNDVEETSRIFKQGYGAYRCKLCPYTHGTL 1589
LT +++ H T E E + E RI Y+C C T
Sbjct: 285 -LTCHRRLH-----TGEKPYKCEECDKAFHFKSILERHRIIHTEEKPYKCNECGKTFRQK 338
Query: 1590 EKLKIHYEKYHNQPEF---DVFSQSPPKLPVPLEPEMTTEVSPSQVSITEEEVGEEPVST 1646
L H+ + + + + K + + T P + + E G+ +
Sbjct: 339 SILTRHHRLHTGEKPYKCNECGKTFSHKSSLTCHHRLHTGEKPYKCN----ECGK---TF 391
Query: 1647 SHFS--TSHLVSHT---VFRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCAL 1701
SH S T H HT ++C+ C S R H +I ++N +KC
Sbjct: 392 SHKSSLTCHRRLHTGEKPYKCEECDKAYSFRSNFEIHRKI---------HTEDNAYKCNE 442
Query: 1702 CAYTNPIRKGLAAHYQKRHDIDAYYTHCLAASRTISDKPNKVIIPSPPKDDSPQLSEELR 1761
C T L H ++RH + Y C + K N + P E
Sbjct: 443 CGKTFSRTSSLTCH-RRRHTGEQPY-KCEECDKAFRFKSNLERHRRIHTGEKPYKCNECG 500
Query: 1762 RAVEKK----------------KCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGG 1805
+ +K KC+ C ++FS K ++ + + H G P K + G
Sbjct: 501 KTFSRKSYLTCHHRLHTGEKAYKCNECG-KTFSWKSSLTCHRRLHSGEKPYK--CKECGK 557
Query: 1806 YFTAVYA-------DEHEKPTLMEEEERGNFEKAEVE-GEAQEIEWLPFRCIKCFKLSFS 1857
F E P E+ ++ K+ +E + E P++C +C K
Sbjct: 558 TFNQQLTLKRHRRLHSGENPYKCEDSDKAYSFKSNLEIHQKIHTEENPYKCNECGKTFSR 617
Query: 1858 TAELLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHNEE 1917
T+ L C H R + G P Y+C+ CD + + L H IH E
Sbjct: 618 TSSLTC------HRR------LHTGEKP------YKCEECDKAFRVKSNLEGHRRIHTGE 659
Query: 1918 FQKRAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVPKIKERKVVGYKCKFCVEVH 1977
K K E K S++ Y E+P YKC C +
Sbjct: 660 --KPYKCNECGK-TFSRKSYFICHHRLHTGEKP-----------------YKCNECGKNF 699
Query: 1978 PTLRAICNHLRKHVQYGNVPAVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFR 2037
++ H R H T E Y C C + +
Sbjct: 700 SQKSSLICHHRLH-----------------------------TGEKPYKCNECGKTFSQK 730
Query: 2038 HNLDRHMQTHHG 2049
NL H + H G
Sbjct: 731 SNLTCHRRLHTG 742
Score = 34.7 bits (78), Expect = 1.2
Identities = 34/148 (22%), Positives = 61/148 (41%), Gaps = 21/148 (14%)
Query: 349 KSPHNSGLVNLTER-SRYGMTDMTNSSADLETNSMLNDSSSDEELNEIDSE-NGLSAMDH 406
KS H++ LV+ +R S T ++N+ + NS L + + E + N +
Sbjct: 166 KSVHDASLVSTAQRISCRPKTHISNNHGNNFWNSSLLTQKQEVHMREKSFQCNESGKAFN 225
Query: 407 QTSGLSAEQLMGSDGNKLLETKGIPFRRFMNRFQCPFCPFLTMHRRSISRHIENIHLSGK 466
+S L Q++ ++++C C L +R+++ H H
Sbjct: 226 YSSLLRKHQII----------------HLADKYKCDVCGKLFNQKRNLACH-RRCHTGEN 268
Query: 467 TAVYKCDECPFTCKSSLKLGAHKQCHTG 494
YKC+EC T + L H++ HTG
Sbjct: 269 P--YKCNECGKTFSQTSSLTCHRRLHTG 294
Score = 34.3 bits (77), Expect = 1.6
Identities = 18/56 (32%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C H+ S++ H +H K YKC+EC T L H++ HTG
Sbjct: 354 YKCNECGKTFSHKSSLTCH-HRLHTGEKP--YKCNECGKTFSHKSSLTCHRRLHTG 406
Score = 32.0 bits (71), Expect = 7.9
Identities = 18/56 (32%), Positives = 25/56 (44%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C + ++ RH IH K YKC+EC T L H + HTG
Sbjct: 466 YKCEECDKAFRFKSNLERH-RRIHTGEKP--YKCNECGKTFSRKSYLTCHHRLHTG 518
>gi|221307571 zinc finger protein 234 [Homo sapiens]
Length = 700
Score = 99.8 bits (247), Expect = 3e-20
Identities = 132/511 (25%), Positives = 186/511 (36%), Gaps = 90/511 (17%)
Query: 1892 YQCKHCDSKLQSTAELTSHLNIHNEEFQKRA----KRQERRKQLLSKQKYADGAFADFKQ 1947
Y+C C + ++ L +H +H E + K RR L K G +
Sbjct: 204 YKCDVCGKEFSQSSHLQTHQRVHTVEKPFKCVECGKGFSRRSTLTVHCKLHSGEKPYNCE 263
Query: 1948 E--RPF---GHLEEVPKIKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVP----- 1997
E R F HL+E +I + +KC C + A+ NH H G P
Sbjct: 264 ECGRAFIHASHLQEHQRIHTGEKP-FKCDTCGKNFRRRSALNNHCMVHT--GEKPYKCED 320
Query: 1998 --AVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFR 2055
LR H+R H T E Y C+ C H + H G KP+
Sbjct: 321 CGKCFTCSSNLRIHQRVH------TGEKPYKCEECGKCFIQPSQFQAHRRIHTGE-KPYV 373
Query: 2056 CKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWC--SFSTMTISQL--------KEHSLKV 2105
CK+C Y+S + H H GE YKC+ C SF Q+ K + +V
Sbjct: 374 CKVCGKGFIYSSSFQAH-QGVHTGEKPYKCNECGKSFRMKIHYQVHLVVHTGEKPYKCEV 432
Query: 2106 HGKALTLPRPRIVSLLSSH-SHHSSQKATPAEEV-EDSNDSSYSEPPDVQQQLNHYQSAA 2163
GKA R S L H HS QK EE + N SS + QL H
Sbjct: 433 CGKAF-----RQSSYLKIHLKAHSVQKPFKCEECGQGFNQSSRLQI----HQLIH----- 478
Query: 2164 LARNNSRVSPVPLSGAAAGTEQKTEAVLHCEF--------CEFSSGYIQSIRRH---YRD 2212
+ P G ++ + +HC CE G + S H ++
Sbjct: 479 -----TGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCE-ECGKVFSQASHLLTHQR 532
Query: 2213 KHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDH 2272
H G+K FKC++C G + + H++A H V G K +C C K+ N+ H
Sbjct: 533 VHSGEKPFKCEEC----GKSFSRSAHLQA-HQKV-HTGEKPYKCGECGKGFKWSLNLDMH 586
Query: 2273 IVLHREERVVPIEVCRSKLSK----------YLQGVVFRCDKCTFTCSSDESLQQHIEKH 2322
+H E+ C S+ + ++CD C S LQ H H
Sbjct: 587 QRVHTGEKPYTCGECGKHFSQASSLQLHQSVHTGEKPYKCDVCGKVFSRSSQLQYHRRVH 646
Query: 2323 NELKPYKCQLCYYETKHTEELDSHLRDEHKV 2353
KPYKC++C L SH HK+
Sbjct: 647 TGEKPYKCEICGKRFSWRSNLVSH----HKI 673
Score = 85.5 bits (210), Expect = 6e-16
Identities = 106/487 (21%), Positives = 163/487 (33%), Gaps = 70/487 (14%)
Query: 1968 YKCKFCVEVHPTLRAICNHLRKHVQYGNVPAVSAAVKGLRSHERSHLALAMFTREDKYSC 2027
YKC C + + H R H V KG + + + E Y+C
Sbjct: 204 YKCDVCGKEFSQSSHLQTHQRVHTVEKPFKCVECG-KGFSRRSTLTVHCKLHSGEKPYNC 262
Query: 2028 QYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSW 2087
+ C +L H + H G KPF+C C S L H + H GE YKC
Sbjct: 263 EECGRAFIHASHLQEHQRIHTGE-KPFKCDTCGKNFRRRSALNNHCM-VHTGEKPYKCED 320
Query: 2088 CSFSTMTISQLKEHSLKVH-----------GKALTLPRPRIVSLLSSHSH-HSSQKATPA 2135
C S L+ H +VH GK P S +H H+ +K
Sbjct: 321 CGKCFTCSSNLRIHQ-RVHTGEKPYKCEECGKCFIQP-----SQFQAHRRIHTGEKPYVC 374
Query: 2136 EEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEF 2195
+ YS Q ++ + + + + E CE
Sbjct: 375 KVC--GKGFIYSSSFQAHQGVHTGEKPYKCNECGKSFRMKIHYQVHLVVHTGEKPYKCEV 432
Query: 2196 CEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLR 2255
C + ++ H + H +K FKC++C GF + + + H + G K +
Sbjct: 433 CGKAFRQSSYLKIHLK-AHSVQKPFKCEECG--QGFNQSSRLQI---HQLI-HTGEKPYK 485
Query: 2256 CPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVV----------FRCDKC 2305
C C + ++ H +H E+ E C S+ + F+C++C
Sbjct: 486 CEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFSQASHLLTHQRVHSGEKPFKCEEC 545
Query: 2306 TFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFELVGRVNL 2365
+ S LQ H + H KPYKC C K + LD H R G
Sbjct: 546 GKSFSRSAHLQAHQKVHTGEKPYKCGECGKGFKWSLNLDMHQRVH---------TGEKPY 596
Query: 2366 DQLEQMKEKMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQ 2425
E K ++SS H + EK + C+ CG+ FS+
Sbjct: 597 TCGECGKHFSQASS---------------------LQLHQSVHTGEKPYKCDVCGKVFSR 635
Query: 2426 GSEWERH 2432
S+ + H
Sbjct: 636 SSQLQYH 642
Score = 83.2 bits (204), Expect = 3e-15
Identities = 117/480 (24%), Positives = 174/480 (36%), Gaps = 81/480 (16%)
Query: 2006 LRSHERSHLALAMFTREDKYSCQY---------------C-----SFVSAFRHNLDRHMQ 2045
L +E S ++++ F R+ SCQ C SF F N D H Q
Sbjct: 111 LIKYEDSMISISRFPRQGDLSCQVRAGLYTTHTGQKFYQCDEYKKSFTDVF--NFDLHQQ 168
Query: 2046 THHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKV 2105
H G K C C Y S L H + H GE YKC C S L+ H +V
Sbjct: 169 LHSGE-KSHTCDECGKSFCYISALHIH-QRVHMGEKCYKCDVCGKEFSQSSHLQTHQ-RV 225
Query: 2106 HGKALTLPRP-----------RIVSLLSSHSHHSSQKATPAEEVEDS--NDSSYSEPPDV 2152
H T+ +P R +L HS +K EE + + S E +
Sbjct: 226 H----TVEKPFKCVECGKGFSRRSTLTVHCKLHSGEKPYNCEECGRAFIHASHLQEHQRI 281
Query: 2153 QQQLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRD 2212
++ +N R S + + T +K CE C ++R H R
Sbjct: 282 HTGEKPFKCDTCGKNFRRRSALN-NHCMVHTGEKP---YKCEDCGKCFTCSSNLRIHQR- 336
Query: 2213 KHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDH 2272
H G+K +KC++C S F H G K C +C Y + H
Sbjct: 337 VHTGEKPYKCEECGKCFIQPSQFQAHRRI------HTGEKPYVCKVCGKGFIYSSSFQAH 390
Query: 2273 IVLHREERVVPIEVCRSKLSKYLQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQL 2332
+H E+ ++C++C + Q H+ H KPYKC++
Sbjct: 391 QGVHTGEK------------------PYKCNECGKSFRMKIHYQVHLVVHTGEKPYKCEV 432
Query: 2333 CYYETKHTEELDSHLRDEHKVSRNF--ELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMN 2390
C + + L HL+ H V + F E G+ +Q +++ + + K EE
Sbjct: 433 CGKAFRQSSYLKIHLK-AHSVQKPFKCEECGQ-GFNQSSRLQIHQLIHTGEKPYKCEECG 490
Query: 2391 SKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRHGMALNDTKQVSREE 2450
R ++ H EK + CE CG+ FSQ S H+L H + K EE
Sbjct: 491 KGFSRRADLKI--HCRIHTGEKPYNCEECGKVFSQAS----HLLTHQRVHSGEKPFKCEE 544
Score = 34.7 bits (78), Expect = 1.2
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 7/58 (12%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECP--FTCKSSLKLGAHKQCHTG 494
F+C C R +++ H +H K YKC++C FTC S+L++ H++ HTG
Sbjct: 288 FKCDTCGKNFRRRSALNNHCM-VHTGEKP--YKCEDCGKCFTCSSNLRI--HQRVHTG 340
Score = 32.0 bits (71), Expect = 7.9
Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
F+C C + H + +H K YKC EC K SL L H++ HTG
Sbjct: 540 FKCEECGKSFSRSAHLQAH-QKVHTGEKP--YKCGECGKGFKWSLNLDMHQRVHTG 592
>gi|24307913 zinc finger protein 234 [Homo sapiens]
Length = 700
Score = 99.8 bits (247), Expect = 3e-20
Identities = 132/511 (25%), Positives = 186/511 (36%), Gaps = 90/511 (17%)
Query: 1892 YQCKHCDSKLQSTAELTSHLNIHNEEFQKRA----KRQERRKQLLSKQKYADGAFADFKQ 1947
Y+C C + ++ L +H +H E + K RR L K G +
Sbjct: 204 YKCDVCGKEFSQSSHLQTHQRVHTVEKPFKCVECGKGFSRRSTLTVHCKLHSGEKPYNCE 263
Query: 1948 E--RPF---GHLEEVPKIKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVP----- 1997
E R F HL+E +I + +KC C + A+ NH H G P
Sbjct: 264 ECGRAFIHASHLQEHQRIHTGEKP-FKCDTCGKNFRRRSALNNHCMVHT--GEKPYKCED 320
Query: 1998 --AVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFR 2055
LR H+R H T E Y C+ C H + H G KP+
Sbjct: 321 CGKCFTCSSNLRIHQRVH------TGEKPYKCEECGKCFIQPSQFQAHRRIHTGE-KPYV 373
Query: 2056 CKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWC--SFSTMTISQL--------KEHSLKV 2105
CK+C Y+S + H H GE YKC+ C SF Q+ K + +V
Sbjct: 374 CKVCGKGFIYSSSFQAH-QGVHTGEKPYKCNECGKSFRMKIHYQVHLVVHTGEKPYKCEV 432
Query: 2106 HGKALTLPRPRIVSLLSSH-SHHSSQKATPAEEV-EDSNDSSYSEPPDVQQQLNHYQSAA 2163
GKA R S L H HS QK EE + N SS + QL H
Sbjct: 433 CGKAF-----RQSSYLKIHLKAHSVQKPFKCEECGQGFNQSSRLQI----HQLIH----- 478
Query: 2164 LARNNSRVSPVPLSGAAAGTEQKTEAVLHCEF--------CEFSSGYIQSIRRH---YRD 2212
+ P G ++ + +HC CE G + S H ++
Sbjct: 479 -----TGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCE-ECGKVFSQASHLLTHQR 532
Query: 2213 KHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDH 2272
H G+K FKC++C G + + H++A H V G K +C C K+ N+ H
Sbjct: 533 VHSGEKPFKCEEC----GKSFSRSAHLQA-HQKV-HTGEKPYKCGECGKGFKWSLNLDMH 586
Query: 2273 IVLHREERVVPIEVCRSKLSK----------YLQGVVFRCDKCTFTCSSDESLQQHIEKH 2322
+H E+ C S+ + ++CD C S LQ H H
Sbjct: 587 QRVHTGEKPYTCGECGKHFSQASSLQLHQSVHTGEKPYKCDVCGKVFSRSSQLQYHRRVH 646
Query: 2323 NELKPYKCQLCYYETKHTEELDSHLRDEHKV 2353
KPYKC++C L SH HK+
Sbjct: 647 TGEKPYKCEICGKRFSWRSNLVSH----HKI 673
Score = 85.5 bits (210), Expect = 6e-16
Identities = 106/487 (21%), Positives = 163/487 (33%), Gaps = 70/487 (14%)
Query: 1968 YKCKFCVEVHPTLRAICNHLRKHVQYGNVPAVSAAVKGLRSHERSHLALAMFTREDKYSC 2027
YKC C + + H R H V KG + + + E Y+C
Sbjct: 204 YKCDVCGKEFSQSSHLQTHQRVHTVEKPFKCVECG-KGFSRRSTLTVHCKLHSGEKPYNC 262
Query: 2028 QYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSW 2087
+ C +L H + H G KPF+C C S L H + H GE YKC
Sbjct: 263 EECGRAFIHASHLQEHQRIHTGE-KPFKCDTCGKNFRRRSALNNHCM-VHTGEKPYKCED 320
Query: 2088 CSFSTMTISQLKEHSLKVH-----------GKALTLPRPRIVSLLSSHSH-HSSQKATPA 2135
C S L+ H +VH GK P S +H H+ +K
Sbjct: 321 CGKCFTCSSNLRIHQ-RVHTGEKPYKCEECGKCFIQP-----SQFQAHRRIHTGEKPYVC 374
Query: 2136 EEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEF 2195
+ YS Q ++ + + + + E CE
Sbjct: 375 KVC--GKGFIYSSSFQAHQGVHTGEKPYKCNECGKSFRMKIHYQVHLVVHTGEKPYKCEV 432
Query: 2196 CEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLR 2255
C + ++ H + H +K FKC++C GF + + + H + G K +
Sbjct: 433 CGKAFRQSSYLKIHLK-AHSVQKPFKCEECG--QGFNQSSRLQI---HQLI-HTGEKPYK 485
Query: 2256 CPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVV----------FRCDKC 2305
C C + ++ H +H E+ E C S+ + F+C++C
Sbjct: 486 CEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFSQASHLLTHQRVHSGEKPFKCEEC 545
Query: 2306 TFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFELVGRVNL 2365
+ S LQ H + H KPYKC C K + LD H R G
Sbjct: 546 GKSFSRSAHLQAHQKVHTGEKPYKCGECGKGFKWSLNLDMHQRVH---------TGEKPY 596
Query: 2366 DQLEQMKEKMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQ 2425
E K ++SS H + EK + C+ CG+ FS+
Sbjct: 597 TCGECGKHFSQASS---------------------LQLHQSVHTGEKPYKCDVCGKVFSR 635
Query: 2426 GSEWERH 2432
S+ + H
Sbjct: 636 SSQLQYH 642
Score = 83.2 bits (204), Expect = 3e-15
Identities = 117/480 (24%), Positives = 174/480 (36%), Gaps = 81/480 (16%)
Query: 2006 LRSHERSHLALAMFTREDKYSCQY---------------C-----SFVSAFRHNLDRHMQ 2045
L +E S ++++ F R+ SCQ C SF F N D H Q
Sbjct: 111 LIKYEDSMISISRFPRQGDLSCQVRAGLYTTHTGQKFYQCDEYKKSFTDVF--NFDLHQQ 168
Query: 2046 THHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKV 2105
H G K C C Y S L H + H GE YKC C S L+ H +V
Sbjct: 169 LHSGE-KSHTCDECGKSFCYISALHIH-QRVHMGEKCYKCDVCGKEFSQSSHLQTHQ-RV 225
Query: 2106 HGKALTLPRP-----------RIVSLLSSHSHHSSQKATPAEEVEDS--NDSSYSEPPDV 2152
H T+ +P R +L HS +K EE + + S E +
Sbjct: 226 H----TVEKPFKCVECGKGFSRRSTLTVHCKLHSGEKPYNCEECGRAFIHASHLQEHQRI 281
Query: 2153 QQQLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRD 2212
++ +N R S + + T +K CE C ++R H R
Sbjct: 282 HTGEKPFKCDTCGKNFRRRSALN-NHCMVHTGEKP---YKCEDCGKCFTCSSNLRIHQR- 336
Query: 2213 KHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDH 2272
H G+K +KC++C S F H G K C +C Y + H
Sbjct: 337 VHTGEKPYKCEECGKCFIQPSQFQAHRRI------HTGEKPYVCKVCGKGFIYSSSFQAH 390
Query: 2273 IVLHREERVVPIEVCRSKLSKYLQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQL 2332
+H E+ ++C++C + Q H+ H KPYKC++
Sbjct: 391 QGVHTGEK------------------PYKCNECGKSFRMKIHYQVHLVVHTGEKPYKCEV 432
Query: 2333 CYYETKHTEELDSHLRDEHKVSRNF--ELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMN 2390
C + + L HL+ H V + F E G+ +Q +++ + + K EE
Sbjct: 433 CGKAFRQSSYLKIHLK-AHSVQKPFKCEECGQ-GFNQSSRLQIHQLIHTGEKPYKCEECG 490
Query: 2391 SKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRHGMALNDTKQVSREE 2450
R ++ H EK + CE CG+ FSQ S H+L H + K EE
Sbjct: 491 KGFSRRADLKI--HCRIHTGEKPYNCEECGKVFSQAS----HLLTHQRVHSGEKPFKCEE 544
Score = 34.7 bits (78), Expect = 1.2
Identities = 20/58 (34%), Positives = 32/58 (55%), Gaps = 7/58 (12%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECP--FTCKSSLKLGAHKQCHTG 494
F+C C R +++ H +H K YKC++C FTC S+L++ H++ HTG
Sbjct: 288 FKCDTCGKNFRRRSALNNHCM-VHTGEKP--YKCEDCGKCFTCSSNLRI--HQRVHTG 340
Score = 32.0 bits (71), Expect = 7.9
Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
F+C C + H + +H K YKC EC K SL L H++ HTG
Sbjct: 540 FKCEECGKSFSRSAHLQAH-QKVHTGEKP--YKCGECGKGFKWSLNLDMHQRVHTG 592
>gi|96303826 zinc finger protein 16 [Homo sapiens]
Length = 682
Score = 99.0 bits (245), Expect = 5e-20
Identities = 111/478 (23%), Positives = 173/478 (36%), Gaps = 97/478 (20%)
Query: 2006 LRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLD--RHMQTHHGHHKPFRCKLCSFKS 2063
L++ RSH++ E Y C C AFR + D RH Q+HH +P+ C C
Sbjct: 252 LKNRHRSHMS------EKAYQCSECG--KAFRGHSDFSRH-QSHHSSERPYMCNECGKAF 302
Query: 2064 SYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVH-----------GKALTL 2112
S NS LK H K+H E Y+C+ C + S L +H ++H GKA
Sbjct: 303 SQNSSLKKH-QKSHMSEKPYECNECGKAFRRSSNLIQHQ-RIHSGEKPYVCSECGKAFR- 359
Query: 2113 PRPRIVSLLSSHSHHSSQKATPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNSRVS 2172
R +L+ H H+ +K E + + +A R + RV
Sbjct: 360 ---RSSNLIKHHRTHTGEKPFECGECGKA-----------------FSQSAHLRKHQRV- 398
Query: 2173 PVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCS------ 2226
E C C + ++ +H+R H G+K +KC DC
Sbjct: 399 ------------HTGEKPYECNDCGKPFSRVSNLIKHHR-VHTGEKPYKCSDCGKAFSQS 445
Query: 2227 --------FYTGFK--------SAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMI 2270
+TG K AF+ + G K RC +C + +I
Sbjct: 446 SSLIQHRRIHTGEKPHVCNVCGKAFSYSSVLRKHQIIHTGEKPYRCSVCGKAFSHSSALI 505
Query: 2271 DHIVLHREERVVPIEVCRSKLSKYLQGVV----------FRCDKCTFTCSSDESLQQHIE 2320
H +H ++ C + ++ + C +C T S +L QH
Sbjct: 506 QHQGVHTGDKPYACHECGKTFGRSSNLILHQRVHTGEKPYECTECGKTFSQSSTLIQHQR 565
Query: 2321 KHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFELV--GRVNLDQLEQMKEKMESS 2378
HN LKP++C C + L H + H + + V G+ Q + +
Sbjct: 566 IHNGLKPHECNQCGKAFNRSSNLIHH-QKVHTGEKPYTCVECGK-GFSQSSHLIQHQIIH 623
Query: 2379 SSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRH 2436
+ + K E R ++ H K + C CG+AFSQ S+ +H L H
Sbjct: 624 TGERPYKCSECGKAFSQRSVL--IQHQRIHTGVKPYDCAACGKAFSQRSKLIKHQLIH 679
Score = 67.4 bits (163), Expect = 2e-10
Identities = 101/459 (22%), Positives = 155/459 (33%), Gaps = 92/459 (20%)
Query: 1845 PFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQST 1904
P+ C +C K +FS L H H S Y+C C + +
Sbjct: 292 PYMCNECGK-AFSQNSSLKKHQKSHMSE-----------------KPYECNECGKAFRRS 333
Query: 1905 AELTSHLNIHNEE----FQKRAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVPKI 1960
+ L H IH+ E + K R L+ + G E+PF
Sbjct: 334 SNLIQHQRIHSGEKPYVCSECGKAFRRSSNLIKHHRTHTG-------EKPF--------- 377
Query: 1961 KERKVVGYKCKFCVEVHPTLRAICNHLRKH--VQYGNVP-------AVSAAVKGLRSHER 2011
+C C + + HLRKH V G P + V L H R
Sbjct: 378 --------ECGECGKAF----SQSAHLRKHQRVHTGEKPYECNDCGKPFSRVSNLIKHHR 425
Query: 2012 SHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKT 2071
H T E Y C C + +L +H + H G KP C +C SY+S L+
Sbjct: 426 VH------TGEKPYKCSDCGKAFSQSSSLIQHRRIHTG-EKPHVCNVCGKAFSYSSVLRK 478
Query: 2072 HILKAHAGEHAYKCSWCSFSTMTISQLKEHS--------LKVHGKALTLPRPRIVSLLSS 2123
H + H GE Y+CS C + S L +H H T R +L+
Sbjct: 479 HQI-IHTGEKPYRCSVCGKAFSHSSALIQHQGVHTGDKPYACHECGKTFGRSS--NLILH 535
Query: 2124 HSHHSSQKATPAEEVED--SNDSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAA 2181
H+ +K E S S+ + + L ++ + +R S + +
Sbjct: 536 QRVHTGEKPYECTECGKTFSQSSTLIQHQRIHNGLKPHECNQCGKAFNRSSNL-IHHQKV 594
Query: 2182 GTEQKTEAVLHCEFCEFSSGYIQSIRR-HYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVE 2240
T +K + C G+ QS ++ H G++ +KC +C +S H
Sbjct: 595 HTGEKPYTCVEC-----GKGFSQSSHLIQHQIIHTGERPYKCSECGKAFSQRSVLIQHQR 649
Query: 2241 AGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREE 2279
G K C C + +I H ++H E
Sbjct: 650 I------HTGVKPYDCAACGKAFSQRSKLIKHQLIHTRE 682
Score = 40.4 bits (93), Expect = 0.022
Identities = 35/140 (25%), Positives = 53/140 (37%), Gaps = 8/140 (5%)
Query: 2300 FRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNF-- 2357
F CD C T S + L+ H K Y+C C + + H + H R +
Sbjct: 237 FMCDDCGKTFSQNSVLKNRHRSHMSEKAYQCSECGKAFRGHSDFSRH-QSHHSSERPYMC 295
Query: 2358 ELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAED-RELMRFSDHGAALNTEKRFPC 2416
G+ Q +K+ +S S +K E N + R H + EK + C
Sbjct: 296 NECGKA-FSQNSSLKKHQKSHMS---EKPYECNECGKAFRRSSNLIQHQRIHSGEKPYVC 351
Query: 2417 EFCGRAFSQGSEWERHVLRH 2436
CG+AF + S +H H
Sbjct: 352 SECGKAFRRSSNLIKHHRTH 371
Score = 39.3 bits (90), Expect = 0.049
Identities = 87/489 (17%), Positives = 150/489 (30%), Gaps = 106/489 (21%)
Query: 1439 EQEAECPEDARLSPEKSLQLASANPAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPGMKV 1498
E+ C E + + S +S PY+C C + L+ H + H G K
Sbjct: 290 ERPYMCNECGKAFSQNSSLKKHQKSHMSEKPYECNECGKAFRRSSNLIQHQ-RIHSGEKP 348
Query: 1499 KAADFAQDIDINPGAVYKCRHCPYINTRIHGVLTHYQKRHPSIKVTAEDFVHDVEQSADI 1558
Y C C R ++ H++ + QSA +
Sbjct: 349 ----------------YVCSECGKAFRRSSNLIKHHRTHTGEKPFECGECGKAFSQSAHL 392
Query: 1559 SQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFD------VFSQSP 1612
++ T G Y C C + L H+ + + + FSQS
Sbjct: 393 RKHQRVHT------GEKPYECNDCGKPFSRVSNLIKHHRVHTGEKPYKCSDCGKAFSQSS 446
Query: 1613 PKLPVPLEPEMTTEVSPSQVSITEEEVGEEPVSTSHFSTSHLVSHT---VFRCQLCKYFC 1669
+ + T P ++ + S S H + HT +RC +C
Sbjct: 447 SLIQ---HRRIHTGEKPHVCNVCGKAF-----SYSSVLRKHQIIHTGEKPYRCSVCGKAF 498
Query: 1670 STRKGIARHYRIKHNNVRAQPEGKNNLFKCALCAYTNPIRKGLAAHYQKRHDIDAYYTHC 1729
S + +H + + + C C T L H Q+ H + Y C
Sbjct: 499 SHSSALIQHQGVHTGD---------KPYACHECGKTFGRSSNLILH-QRVHTGEKPY-EC 547
Query: 1730 LAASRTISDKPNKVIIPSPPKDDSPQLSEELRRAVEKKKCSLCSFQSFSKKGIVSHYMKR 1789
+T S + + + ++ +C+ C ++F++ + H+ K
Sbjct: 548 TECGKTFSQSSTLI------------QHQRIHNGLKPHECNQCG-KAFNRSSNLIHHQKV 594
Query: 1790 HPGVFPKKQHASKLGGYFTAVYADEHEKPTLMEEEERGNFEKAE-VEGEAQEIEWLPFRC 1848
H G EKP E +G + + ++ + P++C
Sbjct: 595 HTG-----------------------EKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKC 631
Query: 1849 IKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQSTAELT 1908
+C K +FS +L H H G P Y C C ++L
Sbjct: 632 SECGK-AFSQRSVLIQHQRIH-----------TGVKP------YDCAACGKAFSQRSKLI 673
Query: 1909 SHLNIHNEE 1917
H IH E
Sbjct: 674 KHQLIHTRE 682
Score = 36.2 bits (82), Expect = 0.42
Identities = 58/273 (21%), Positives = 94/273 (34%), Gaps = 60/273 (21%)
Query: 1768 KCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGYFTAVYADEHEKPTLMEEEERG 1827
KCS C ++FS+ + + + H G +K H + G + Y+ K ++ E+
Sbjct: 434 KCSDCG-KAFSQSSSLIQHRRIHTG---EKPHVCNVCGKAFS-YSSVLRKHQIIHTGEK- 487
Query: 1828 NFEKAEVEGEAQEIEWLPFRCIKCFKLSFSTAELLCMHYTDHHS------RDLKRDF--- 1878
P+RC C K +FS + L H H + + F
Sbjct: 488 -----------------PYRCSVCGK-AFSHSSALIQHQGVHTGDKPYACHECGKTFGRS 529
Query: 1879 --IILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHN----EEFQKRAKRQERRKQLL 1932
+IL Y+C C ++ L H IHN E + K R L+
Sbjct: 530 SNLILHQRVHTGEKPYECTECGKTFSQSSTLIQHQRIHNGLKPHECNQCGKAFNRSSNLI 589
Query: 1933 SKQKYADGAFADFKQERPFGHLE------EVPKIKERKVV-----GYKCKFCVEVHPTLR 1981
QK G E+P+ +E + + + +++ YKC C +
Sbjct: 590 HHQKVHTG-------EKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCSECGKAFSQRS 642
Query: 1982 AICNHLRKHVQYGNVPAVSAAVKGLRSHERSHL 2014
+ H R H V A G +RS L
Sbjct: 643 VLIQHQRIHT---GVKPYDCAACGKAFSQRSKL 672
>gi|38045954 zinc finger protein 16 [Homo sapiens]
Length = 682
Score = 99.0 bits (245), Expect = 5e-20
Identities = 111/478 (23%), Positives = 173/478 (36%), Gaps = 97/478 (20%)
Query: 2006 LRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLD--RHMQTHHGHHKPFRCKLCSFKS 2063
L++ RSH++ E Y C C AFR + D RH Q+HH +P+ C C
Sbjct: 252 LKNRHRSHMS------EKAYQCSECG--KAFRGHSDFSRH-QSHHSSERPYMCNECGKAF 302
Query: 2064 SYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVH-----------GKALTL 2112
S NS LK H K+H E Y+C+ C + S L +H ++H GKA
Sbjct: 303 SQNSSLKKH-QKSHMSEKPYECNECGKAFRRSSNLIQHQ-RIHSGEKPYVCSECGKAFR- 359
Query: 2113 PRPRIVSLLSSHSHHSSQKATPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNSRVS 2172
R +L+ H H+ +K E + + +A R + RV
Sbjct: 360 ---RSSNLIKHHRTHTGEKPFECGECGKA-----------------FSQSAHLRKHQRV- 398
Query: 2173 PVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCS------ 2226
E C C + ++ +H+R H G+K +KC DC
Sbjct: 399 ------------HTGEKPYECNDCGKPFSRVSNLIKHHR-VHTGEKPYKCSDCGKAFSQS 445
Query: 2227 --------FYTGFK--------SAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMI 2270
+TG K AF+ + G K RC +C + +I
Sbjct: 446 SSLIQHRRIHTGEKPHVCNVCGKAFSYSSVLRKHQIIHTGEKPYRCSVCGKAFSHSSALI 505
Query: 2271 DHIVLHREERVVPIEVCRSKLSKYLQGVV----------FRCDKCTFTCSSDESLQQHIE 2320
H +H ++ C + ++ + C +C T S +L QH
Sbjct: 506 QHQGVHTGDKPYACHECGKTFGRSSNLILHQRVHTGEKPYECTECGKTFSQSSTLIQHQR 565
Query: 2321 KHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFELV--GRVNLDQLEQMKEKMESS 2378
HN LKP++C C + L H + H + + V G+ Q + +
Sbjct: 566 IHNGLKPHECNQCGKAFNRSSNLIHH-QKVHTGEKPYTCVECGK-GFSQSSHLIQHQIIH 623
Query: 2379 SSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRH 2436
+ + K E R ++ H K + C CG+AFSQ S+ +H L H
Sbjct: 624 TGERPYKCSECGKAFSQRSVL--IQHQRIHTGVKPYDCAACGKAFSQRSKLIKHQLIH 679
Score = 67.4 bits (163), Expect = 2e-10
Identities = 101/459 (22%), Positives = 155/459 (33%), Gaps = 92/459 (20%)
Query: 1845 PFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQST 1904
P+ C +C K +FS L H H S Y+C C + +
Sbjct: 292 PYMCNECGK-AFSQNSSLKKHQKSHMSE-----------------KPYECNECGKAFRRS 333
Query: 1905 AELTSHLNIHNEE----FQKRAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVPKI 1960
+ L H IH+ E + K R L+ + G E+PF
Sbjct: 334 SNLIQHQRIHSGEKPYVCSECGKAFRRSSNLIKHHRTHTG-------EKPF--------- 377
Query: 1961 KERKVVGYKCKFCVEVHPTLRAICNHLRKH--VQYGNVP-------AVSAAVKGLRSHER 2011
+C C + + HLRKH V G P + V L H R
Sbjct: 378 --------ECGECGKAF----SQSAHLRKHQRVHTGEKPYECNDCGKPFSRVSNLIKHHR 425
Query: 2012 SHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKT 2071
H T E Y C C + +L +H + H G KP C +C SY+S L+
Sbjct: 426 VH------TGEKPYKCSDCGKAFSQSSSLIQHRRIHTG-EKPHVCNVCGKAFSYSSVLRK 478
Query: 2072 HILKAHAGEHAYKCSWCSFSTMTISQLKEHS--------LKVHGKALTLPRPRIVSLLSS 2123
H + H GE Y+CS C + S L +H H T R +L+
Sbjct: 479 HQI-IHTGEKPYRCSVCGKAFSHSSALIQHQGVHTGDKPYACHECGKTFGRSS--NLILH 535
Query: 2124 HSHHSSQKATPAEEVED--SNDSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAA 2181
H+ +K E S S+ + + L ++ + +R S + +
Sbjct: 536 QRVHTGEKPYECTECGKTFSQSSTLIQHQRIHNGLKPHECNQCGKAFNRSSNL-IHHQKV 594
Query: 2182 GTEQKTEAVLHCEFCEFSSGYIQSIRR-HYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVE 2240
T +K + C G+ QS ++ H G++ +KC +C +S H
Sbjct: 595 HTGEKPYTCVEC-----GKGFSQSSHLIQHQIIHTGERPYKCSECGKAFSQRSVLIQHQR 649
Query: 2241 AGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREE 2279
G K C C + +I H ++H E
Sbjct: 650 I------HTGVKPYDCAACGKAFSQRSKLIKHQLIHTRE 682
Score = 40.4 bits (93), Expect = 0.022
Identities = 35/140 (25%), Positives = 53/140 (37%), Gaps = 8/140 (5%)
Query: 2300 FRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNF-- 2357
F CD C T S + L+ H K Y+C C + + H + H R +
Sbjct: 237 FMCDDCGKTFSQNSVLKNRHRSHMSEKAYQCSECGKAFRGHSDFSRH-QSHHSSERPYMC 295
Query: 2358 ELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAED-RELMRFSDHGAALNTEKRFPC 2416
G+ Q +K+ +S S +K E N + R H + EK + C
Sbjct: 296 NECGKA-FSQNSSLKKHQKSHMS---EKPYECNECGKAFRRSSNLIQHQRIHSGEKPYVC 351
Query: 2417 EFCGRAFSQGSEWERHVLRH 2436
CG+AF + S +H H
Sbjct: 352 SECGKAFRRSSNLIKHHRTH 371
Score = 39.3 bits (90), Expect = 0.049
Identities = 87/489 (17%), Positives = 150/489 (30%), Gaps = 106/489 (21%)
Query: 1439 EQEAECPEDARLSPEKSLQLASANPAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPGMKV 1498
E+ C E + + S +S PY+C C + L+ H + H G K
Sbjct: 290 ERPYMCNECGKAFSQNSSLKKHQKSHMSEKPYECNECGKAFRRSSNLIQHQ-RIHSGEKP 348
Query: 1499 KAADFAQDIDINPGAVYKCRHCPYINTRIHGVLTHYQKRHPSIKVTAEDFVHDVEQSADI 1558
Y C C R ++ H++ + QSA +
Sbjct: 349 ----------------YVCSECGKAFRRSSNLIKHHRTHTGEKPFECGECGKAFSQSAHL 392
Query: 1559 SQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFD------VFSQSP 1612
++ T G Y C C + L H+ + + + FSQS
Sbjct: 393 RKHQRVHT------GEKPYECNDCGKPFSRVSNLIKHHRVHTGEKPYKCSDCGKAFSQSS 446
Query: 1613 PKLPVPLEPEMTTEVSPSQVSITEEEVGEEPVSTSHFSTSHLVSHT---VFRCQLCKYFC 1669
+ + T P ++ + S S H + HT +RC +C
Sbjct: 447 SLIQ---HRRIHTGEKPHVCNVCGKAF-----SYSSVLRKHQIIHTGEKPYRCSVCGKAF 498
Query: 1670 STRKGIARHYRIKHNNVRAQPEGKNNLFKCALCAYTNPIRKGLAAHYQKRHDIDAYYTHC 1729
S + +H + + + C C T L H Q+ H + Y C
Sbjct: 499 SHSSALIQHQGVHTGD---------KPYACHECGKTFGRSSNLILH-QRVHTGEKPY-EC 547
Query: 1730 LAASRTISDKPNKVIIPSPPKDDSPQLSEELRRAVEKKKCSLCSFQSFSKKGIVSHYMKR 1789
+T S + + + ++ +C+ C ++F++ + H+ K
Sbjct: 548 TECGKTFSQSSTLI------------QHQRIHNGLKPHECNQCG-KAFNRSSNLIHHQKV 594
Query: 1790 HPGVFPKKQHASKLGGYFTAVYADEHEKPTLMEEEERGNFEKAE-VEGEAQEIEWLPFRC 1848
H G EKP E +G + + ++ + P++C
Sbjct: 595 HTG-----------------------EKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKC 631
Query: 1849 IKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQSTAELT 1908
+C K +FS +L H H G P Y C C ++L
Sbjct: 632 SECGK-AFSQRSVLIQHQRIH-----------TGVKP------YDCAACGKAFSQRSKLI 673
Query: 1909 SHLNIHNEE 1917
H IH E
Sbjct: 674 KHQLIHTRE 682
Score = 36.2 bits (82), Expect = 0.42
Identities = 58/273 (21%), Positives = 94/273 (34%), Gaps = 60/273 (21%)
Query: 1768 KCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGYFTAVYADEHEKPTLMEEEERG 1827
KCS C ++FS+ + + + H G +K H + G + Y+ K ++ E+
Sbjct: 434 KCSDCG-KAFSQSSSLIQHRRIHTG---EKPHVCNVCGKAFS-YSSVLRKHQIIHTGEK- 487
Query: 1828 NFEKAEVEGEAQEIEWLPFRCIKCFKLSFSTAELLCMHYTDHHS------RDLKRDF--- 1878
P+RC C K +FS + L H H + + F
Sbjct: 488 -----------------PYRCSVCGK-AFSHSSALIQHQGVHTGDKPYACHECGKTFGRS 529
Query: 1879 --IILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHN----EEFQKRAKRQERRKQLL 1932
+IL Y+C C ++ L H IHN E + K R L+
Sbjct: 530 SNLILHQRVHTGEKPYECTECGKTFSQSSTLIQHQRIHNGLKPHECNQCGKAFNRSSNLI 589
Query: 1933 SKQKYADGAFADFKQERPFGHLE------EVPKIKERKVV-----GYKCKFCVEVHPTLR 1981
QK G E+P+ +E + + + +++ YKC C +
Sbjct: 590 HHQKVHTG-------EKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCSECGKAFSQRS 642
Query: 1982 AICNHLRKHVQYGNVPAVSAAVKGLRSHERSHL 2014
+ H R H V A G +RS L
Sbjct: 643 VLIQHQRIHT---GVKPYDCAACGKAFSQRSKL 672
>gi|115511042 zinc finger protein 493 isoform 1 [Homo sapiens]
Length = 646
Score = 98.6 bits (244), Expect = 7e-20
Identities = 147/653 (22%), Positives = 226/653 (34%), Gaps = 112/653 (17%)
Query: 1845 PFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRD---------FIILGNGPRLQNSTYQCK 1895
PF+C KC K SF LC H H + R F L R+ K
Sbjct: 53 PFKCKKCGK-SFCMLLHLCQHKRIHIRENSYRCEECGKAFIWFSTLTRHRRVHTGEKSYK 111
Query: 1896 H-CDSKLQSTAELTSHLNIHNEEFQKRAKRQE-----RRKQLLSKQKYADGAFADFKQER 1949
+ C + LT+H IH QK K +E + L++ K +K E+
Sbjct: 112 YECGKSFNQDSNLTTHKRIHTG--QKPYKCEECGTSFYQFSYLTRHKLIHTREKPYKCEQ 169
Query: 1950 PFGHLEEVPKIKERKVVG-----YKCKFCVEVH-----PTLRAICNHLRKHVQYGNVPAV 1999
+ + K++ YKC+ C + PT I + K +
Sbjct: 170 YGKTFNQSSTLTGHKIIHNGEKPYKCEECGKAFSIFSTPTKHKIIHTEEKSHRCEEYCKA 229
Query: 2000 SAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLC 2059
L +H+R H T E Y C+ C + L +H + H K RC+ C
Sbjct: 230 YKESSHLTTHKRIH------TGEKPYKCEECGKAFSIFSTLTKH-KIIHTEEKSHRCEEC 282
Query: 2060 SFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSL--------------KV 2105
+S L TH + H GE YKC C + S L +H + K
Sbjct: 283 GKAYKESSHLTTH-KRIHTGEKPYKCEECGKTFSVFSILTKHKIIHTEEKPYKCEECGKA 341
Query: 2106 HGKALTLPRPRIVSLLSSHSHHSSQKATPAEEVEDS--NDSSYSEPPDVQQQLNHYQSAA 2163
++ TL + RI+ H+ +K EE + S+ S + Y+
Sbjct: 342 FKRSSTLTKHRII--------HTEEKPYKCEECGKAFNQSSTLSIHKIIHTGEKPYKCEE 393
Query: 2164 LARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCK 2223
+ R S + + E+ + CE C + + H R H G K +KCK
Sbjct: 394 CGKAFKRSSTLTIHKMIHTGEKPYK----CEECGKAFNRSSHLTTHKRI-HTGHKPYKCK 448
Query: 2224 DCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVP 2283
+C S T H + K +C C + H +H E+
Sbjct: 449 ECGKSFSVFSTLTKH------KIIHTDKKPYKCEECGKAFNRSSILSIHKKIHTGEKPYK 502
Query: 2284 IEVCRS--KLSKYLQG--------VVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLC 2333
E C K S +L G ++C++C S +L +H H E KPYKC+ C
Sbjct: 503 CEECGKAFKRSSHLAGHKQIHSVQKPYKCEECGKAFSIFSTLTKHKIIHTEEKPYKCEKC 562
Query: 2334 YYETKHTEELDSHLRDEHKVSRNFELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKA 2393
+ F +N ++ EK ++ K +S
Sbjct: 563 --------------------GKTFYRFSNLNTHKIIHTGEK--PCKCEECGKAFNHSSNL 600
Query: 2394 EDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRH-GMALNDTKQ 2445
+L+ D K + CE CG+AF + S RH + H G+ +T Q
Sbjct: 601 IKHKLIHTGD--------KPYKCEACGKAFRRSSHLSRHKIIHIGIHTEETVQ 645
Score = 72.8 bits (177), Expect = 4e-12
Identities = 107/458 (23%), Positives = 166/458 (36%), Gaps = 91/458 (19%)
Query: 2023 DKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHA 2082
DKY + +++ RHN T H KPF+CK C L H + H E++
Sbjct: 29 DKYVKVFHKLLNSNRHN------TKHTGKKPFKCKKCGKSFCMLLHLCQH-KRIHIRENS 81
Query: 2083 YKCSWCSFSTMTISQLKEHSLKVH----------GKALTLPRPRIVSLLSSHSH-HSSQK 2131
Y+C C + + S L H +VH GK+ S L++H H+ QK
Sbjct: 82 YRCEECGKAFIWFSTLTRHR-RVHTGEKSYKYECGKSFNQD-----SNLTTHKRIHTGQK 135
Query: 2132 ATPAEEVEDS-NDSSY----------SEPPDVQQQLNHYQSAA------LARNNSR---- 2170
EE S SY +P +Q + ++ + N +
Sbjct: 136 PYKCEECGTSFYQFSYLTRHKLIHTREKPYKCEQYGKTFNQSSTLTGHKIIHNGEKPYKC 195
Query: 2171 --------VSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQS--IRRHYRDKHGGKKLF 2220
+ P TE+K+ CE E+ Y +S + H R H G+K +
Sbjct: 196 EECGKAFSIFSTPTKHKIIHTEEKSH---RCE--EYCKAYKESSHLTTHKR-IHTGEKPY 249
Query: 2221 KCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREER 2280
KC++C S T H + K RC C K ++ H +H E+
Sbjct: 250 KCEECGKAFSIFSTLTKH------KIIHTEEKSHRCEECGKAYKESSHLTTHKRIHTGEK 303
Query: 2281 VVPIEVCRSKLSKYLQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHT 2340
++C++C T S L +H H E KPYKC+ C K +
Sbjct: 304 ------------------PYKCEECGKTFSVFSILTKHKIIHTEEKPYKCEECGKAFKRS 345
Query: 2341 EELDSH--LRDEHKVSRNFELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDREL 2398
L H + E K + E N + + + + ++ + E KA R
Sbjct: 346 STLTKHRIIHTEEKPYKCEECGKAFNQSSTLSIHKIIHTG---EKPYKCEECGKAFKRS- 401
Query: 2399 MRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRH 2436
+ H EK + CE CG+AF++ S H H
Sbjct: 402 STLTIHKMIHTGEKPYKCEECGKAFNRSSHLTTHKRIH 439
Score = 43.1 bits (100), Expect = 0.003
Identities = 39/162 (24%), Positives = 60/162 (37%), Gaps = 28/162 (17%)
Query: 2289 SKLSKYL---QGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQ-----------LCY 2334
++L++YL Q +F+CDK + +H KH KP+KC+ LC
Sbjct: 12 NELNQYLTTTQSKIFQCDKYVKVFHKLLNSNRHNTKHTGKKPFKCKKCGKSFCMLLHLCQ 71
Query: 2335 YETKHTEELDSHLRDEHKVSRNFELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAE 2394
++ H E + K F + R + K E S ++D
Sbjct: 72 HKRIHIRENSYRCEECGKAFIWFSTLTRHRRVHTGEKSYKYECGKSFNQDS--------- 122
Query: 2395 DRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRH 2436
+ H +K + CE CG +F Q S RH L H
Sbjct: 123 -----NLTTHKRIHTGQKPYKCEECGTSFYQFSYLTRHKLIH 159
Score = 32.3 bits (72), Expect = 6.0
Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 3/55 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHT 493
++C C +R SI + IH K YKC+EC K S L HKQ H+
Sbjct: 473 YKCEECG-KAFNRSSILSIHKKIHTGEKP--YKCEECGKAFKRSSHLAGHKQIHS 524
Score = 32.0 bits (71), Expect = 7.9
Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C ++S H + IH K YKC+EC K S L HK HTG
Sbjct: 361 YKCEECGKAFNQSSTLSIH-KIIHTGEKP--YKCEECGKAFKRSSTLTIHKMIHTG 413
>gi|115511044 zinc finger protein 493 isoform 3 [Homo sapiens]
Length = 774
Score = 98.6 bits (244), Expect = 7e-20
Identities = 147/653 (22%), Positives = 226/653 (34%), Gaps = 112/653 (17%)
Query: 1845 PFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRD---------FIILGNGPRLQNSTYQCK 1895
PF+C KC K SF LC H H + R F L R+ K
Sbjct: 181 PFKCKKCGK-SFCMLLHLCQHKRIHIRENSYRCEECGKAFIWFSTLTRHRRVHTGEKSYK 239
Query: 1896 H-CDSKLQSTAELTSHLNIHNEEFQKRAKRQE-----RRKQLLSKQKYADGAFADFKQER 1949
+ C + LT+H IH QK K +E + L++ K +K E+
Sbjct: 240 YECGKSFNQDSNLTTHKRIHTG--QKPYKCEECGTSFYQFSYLTRHKLIHTREKPYKCEQ 297
Query: 1950 PFGHLEEVPKIKERKVVG-----YKCKFCVEVH-----PTLRAICNHLRKHVQYGNVPAV 1999
+ + K++ YKC+ C + PT I + K +
Sbjct: 298 YGKTFNQSSTLTGHKIIHNGEKPYKCEECGKAFSIFSTPTKHKIIHTEEKSHRCEEYCKA 357
Query: 2000 SAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLC 2059
L +H+R H T E Y C+ C + L +H + H K RC+ C
Sbjct: 358 YKESSHLTTHKRIH------TGEKPYKCEECGKAFSIFSTLTKH-KIIHTEEKSHRCEEC 410
Query: 2060 SFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSL--------------KV 2105
+S L TH + H GE YKC C + S L +H + K
Sbjct: 411 GKAYKESSHLTTH-KRIHTGEKPYKCEECGKTFSVFSILTKHKIIHTEEKPYKCEECGKA 469
Query: 2106 HGKALTLPRPRIVSLLSSHSHHSSQKATPAEEVEDS--NDSSYSEPPDVQQQLNHYQSAA 2163
++ TL + RI+ H+ +K EE + S+ S + Y+
Sbjct: 470 FKRSSTLTKHRII--------HTEEKPYKCEECGKAFNQSSTLSIHKIIHTGEKPYKCEE 521
Query: 2164 LARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCK 2223
+ R S + + E+ + CE C + + H R H G K +KCK
Sbjct: 522 CGKAFKRSSTLTIHKMIHTGEKPYK----CEECGKAFNRSSHLTTHKRI-HTGHKPYKCK 576
Query: 2224 DCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVP 2283
+C S T H + K +C C + H +H E+
Sbjct: 577 ECGKSFSVFSTLTKH------KIIHTDKKPYKCEECGKAFNRSSILSIHKKIHTGEKPYK 630
Query: 2284 IEVCRS--KLSKYLQG--------VVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLC 2333
E C K S +L G ++C++C S +L +H H E KPYKC+ C
Sbjct: 631 CEECGKAFKRSSHLAGHKQIHSVQKPYKCEECGKAFSIFSTLTKHKIIHTEEKPYKCEKC 690
Query: 2334 YYETKHTEELDSHLRDEHKVSRNFELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKA 2393
+ F +N ++ EK ++ K +S
Sbjct: 691 --------------------GKTFYRFSNLNTHKIIHTGEK--PCKCEECGKAFNHSSNL 728
Query: 2394 EDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRH-GMALNDTKQ 2445
+L+ D K + CE CG+AF + S RH + H G+ +T Q
Sbjct: 729 IKHKLIHTGD--------KPYKCEACGKAFRRSSHLSRHKIIHIGIHTEETVQ 773
Score = 87.0 bits (214), Expect = 2e-16
Identities = 130/596 (21%), Positives = 207/596 (34%), Gaps = 106/596 (17%)
Query: 1893 QCKHCDSKLQSTAELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERPFG 1952
+C H D +L+ + + N+H E + E + L + Q F K + F
Sbjct: 114 KCGHKDLQLRKGCKSMNECNVHKEGY------NELNQYLTTTQ---SKIFQCDKYVKVFH 164
Query: 1953 HL--EEVPKIKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVPAVSAAVKGLRSHE 2010
L K +KCK C + L +C H R H+
Sbjct: 165 KLLNSNRHNTKHTGKKPFKCKKCGKSFCMLLHLCQHKRIHI------------------- 205
Query: 2011 RSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLK 2070
RE+ Y C+ C + L RH + H G K ++ + C + +S L
Sbjct: 206 ----------RENSYRCEECGKAFIWFSTLTRHRRVHTG-EKSYKYE-CGKSFNQDSNLT 253
Query: 2071 THILKAHAGEHAYKCSWCSFSTMTISQLKEHSL----------KVHGKALTLPRPRIVSL 2120
TH + H G+ YKC C S S L H L + +GK S
Sbjct: 254 TH-KRIHTGQKPYKCEECGTSFYQFSYLTRHKLIHTREKPYKCEQYGKTFNQS-----ST 307
Query: 2121 LSSHS-HHSSQKATPAEEVEDSNDSSYSEPPD------------VQQQLNHYQSAALARN 2167
L+ H H+ +K EE + S +S P ++ Y+ ++
Sbjct: 308 LTGHKIIHNGEKPYKCEECGKA-FSIFSTPTKHKIIHTEEKSHRCEEYCKAYKESSHLTT 366
Query: 2168 NSRV--SPVPLSGAAAG---------TEQK---TEAVLH-CEFCEFSSGYIQSIRRHYRD 2212
+ R+ P G T+ K TE H CE C + + H R
Sbjct: 367 HKRIHTGEKPYKCEECGKAFSIFSTLTKHKIIHTEEKSHRCEECGKAYKESSHLTTHKR- 425
Query: 2213 KHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDH 2272
H G+K +KC++C S T H + K +C C K + H
Sbjct: 426 IHTGEKPYKCEECGKTFSVFSILTKH------KIIHTEEKPYKCEECGKAFKRSSTLTKH 479
Query: 2273 IVLHREERVVPIEVCRSKLSK----------YLQGVVFRCDKCTFTCSSDESLQQHIEKH 2322
++H EE+ E C ++ + ++C++C +L H H
Sbjct: 480 RIIHTEEKPYKCEECGKAFNQSSTLSIHKIIHTGEKPYKCEECGKAFKRSSTLTIHKMIH 539
Query: 2323 NELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFELVGRVNLDQLEQMKEKMESSSSDD 2382
KPYKC+ C + L +H R H + ++ + K + +D
Sbjct: 540 TGEKPYKCEECGKAFNRSSHLTTHKR-IHTGHKPYKCKECGKSFSVFSTLTKHKIIHTDK 598
Query: 2383 EDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRHGM 2438
+ + E KA +R + S H EK + CE CG+AF + S H H +
Sbjct: 599 KPYKCEECGKAFNRSSI-LSIHKKIHTGEKPYKCEECGKAFKRSSHLAGHKQIHSV 653
Score = 32.3 bits (72), Expect = 6.0
Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 3/55 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHT 493
++C C +R SI + IH K YKC+EC K S L HKQ H+
Sbjct: 601 YKCEECG-KAFNRSSILSIHKKIHTGEKP--YKCEECGKAFKRSSHLAGHKQIHS 652
Score = 32.0 bits (71), Expect = 7.9
Identities = 20/56 (35%), Positives = 26/56 (46%), Gaps = 3/56 (5%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
++C C ++S H + IH K YKC+EC K S L HK HTG
Sbjct: 489 YKCEECGKAFNQSSTLSIH-KIIHTGEKP--YKCEECGKAFKRSSTLTIHKMIHTG 541
>gi|71061446 zinc finger protein, X-linked [Homo sapiens]
Length = 805
Score = 98.6 bits (244), Expect = 7e-20
Identities = 99/436 (22%), Positives = 160/436 (36%), Gaps = 59/436 (13%)
Query: 1871 SRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHNEEFQKRAKR-----Q 1925
SR + II +G L + Y C C K +S L H+ H E K+ R
Sbjct: 406 SRQYQTAIIIGPDGHPL--TVYPCMICGKKFKSRGFLKRHMKNHPEHLAKKKYRCTDCDY 463
Query: 1926 ERRKQL-----LSKQKYADGAFADFKQERPFGHLEEVPKIKERKVVG--------YKCKF 1972
K++ L K A + + H + K+V +KCKF
Sbjct: 464 TTNKKISLHNHLESHKLTSKAEKAIECDECGKHFSHAGALFTHKMVHKEKGANKMHKCKF 523
Query: 1973 CVEVHPTLRAICNHLRKHVQYGNVPAVSAAV-KGLRSHERSHLALAMFTREDKYSCQYCS 2031
C E + + N V N P + KG R + + T E Y CQYC
Sbjct: 524 C-EYETAEQGLLNRHLLAVHSKNFPHICVECGKGFRHPSELKKHMRIHTGEKPYQCQYCE 582
Query: 2032 FVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFS 2091
+ SA NL H++T H PF+C +C S ++ H L H ++C C
Sbjct: 583 YRSADSSNLKTHVKTKHSKEMPFKCDICLLTFSDTKEVQQHAL-IHQESKTHQCLHCDHK 641
Query: 2092 TMTISQLKEHSLKVHGKALTLPRPRIVSLLSSHSHHSSQKATPAEEVEDSNDSSYSEPPD 2151
+ S LK H + VH K + H D D + P +
Sbjct: 642 SSNSSDLKRHIISVHTK--------------DYPHKC-----------DMCDKGFHRPSE 676
Query: 2152 VQQQLNHYQSAALAR----NNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIR 2207
+++ + ++ + + + P LS K + C+ C ++
Sbjct: 677 LKKHVAAHKGKKMHQCRHCDFKIADPFVLSRHILSVHTK-DLPFRCKRCRKGFRQQSELK 735
Query: 2208 RHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKR 2267
+H + H G+K+++C+ C + T S F HV + H+ ++ P RC C +
Sbjct: 736 KHMKT-HSGRKVYQCEYCEYSTTDASGFKRHVISIHT---KDYPH--RCEYCKKGFRRPS 789
Query: 2268 NMIDHIVLHREERVVP 2283
HI+ H +E +P
Sbjct: 790 EKNQHIMRHHKEVGLP 805
Score = 85.9 bits (211), Expect = 5e-16
Identities = 97/432 (22%), Positives = 162/432 (37%), Gaps = 78/432 (18%)
Query: 2025 YSCQYCSFVSAFRHNLDRHMQTHHGH--HKPFRCKLCSF----KSSYNSRLKTHILKAHA 2078
Y C C R L RHM+ H H K +RC C + K S ++ L++H L + A
Sbjct: 425 YPCMICGKKFKSRGFLKRHMKNHPEHLAKKKYRCTDCDYTTNKKISLHNHLESHKLTSKA 484
Query: 2079 GEHAYKCSWCSFSTMTISQLKEHSLKVHGKALTLPRPRIVSLLSSHSHHSSQKATPAEEV 2138
E A +C C K S H AL +H K A ++
Sbjct: 485 -EKAIECDECG---------KHFS---HAGAL-------------FTHKMVHKEKGANKM 518
Query: 2139 EDSNDSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEF 2198
Y Q LN + A ++N + C C
Sbjct: 519 HKCKFCEYETAE--QGLLNRHLLAVHSKNFPHI---------------------CVECGK 555
Query: 2199 SSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPL 2258
+ +++H R H G+K ++C+ C + + S HV+ HS +E P +C +
Sbjct: 556 GFRHPSELKKHMRI-HTGEKPYQCQYCEYRSADSSNLKTHVKTKHS---KEMP--FKCDI 609
Query: 2259 CLYHTKYKRNMIDHIVLHREERVVPIEVCRSK-----------LSKYLQGVVFRCDKCTF 2307
CL + + H ++H+E + C K +S + + +CD C
Sbjct: 610 CLLTFSDTKEVQQHALIHQESKTHQCLHCDHKSSNSSDLKRHIISVHTKDYPHKCDMCDK 669
Query: 2308 TCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFELVG-RVNLD 2366
L++H+ H K ++C+ C ++ L H+ H F R
Sbjct: 670 GFHRPSELKKHVAAHKGKKMHQCRHCDFKIADPFVLSRHILSVHTKDLPFRCKRCRKGFR 729
Query: 2367 QLEQMKEKMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEKRFP--CEFCGRAFS 2424
Q ++K+ M++ S + E D F H +++T K +P CE+C + F
Sbjct: 730 QQSELKKHMKTHSGRKVYQCEYCEYSTTDAS--GFKRHVISIHT-KDYPHRCEYCKKGFR 786
Query: 2425 QGSEWERHVLRH 2436
+ SE +H++RH
Sbjct: 787 RPSEKNQHIMRH 798
Score = 72.4 bits (176), Expect = 5e-12
Identities = 90/479 (18%), Positives = 177/479 (36%), Gaps = 119/479 (24%)
Query: 1658 TVFRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCALCAYTNPIRKGLAAHYQ 1717
TV+ C +C +R + RH + H A+ + ++C C YT + L H
Sbjct: 423 TVYPCMICGKKFKSRGFLKRHMK-NHPEHLAKKK-----YRCTDCDYTTNKKISLHNH-- 474
Query: 1718 KRHDIDAYYTHCLAASRTISDKPNKVIIPSPPKDDSPQLSEELRRAVEKKKCSLCSFQSF 1777
++++ A D+ K + + +E + A + KC C +++
Sbjct: 475 ----LESHKLTSKAEKAIECDECGKHFSHAGALFTHKMVHKE-KGANKMHKCKFCEYETA 529
Query: 1778 SKKGIVSHYMKRHPGVFPKK--------QHASKLGGYFTAVYADEHEKPTLMEEEERGNF 1829
+ + H + H FP +H S+L + ++ E E +
Sbjct: 530 EQGLLNRHLLAVHSKNFPHICVECGKGFRHPSELKKHMR-IHTGEKPYQCQYCEYRSADS 588
Query: 1830 EKAEVEGEAQEIEWLPFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQN 1889
+ + + + +PF+C C L+FS + + H H ++
Sbjct: 589 SNLKTHVKTKHSKEMPFKCDICL-LTFSDTKEVQQHALIHQ-----------------ES 630
Query: 1890 STYQCKHCDSKLQSTAELTSHL-NIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQE 1948
T+QC HCD K ++++L H+ ++H +++
Sbjct: 631 KTHQCLHCDHKSSNSSDLKRHIISVHTKDYP----------------------------- 661
Query: 1949 RPFGHLEEVPKIKERKVVGYKCKFCVE-VHPTLRAICNHLRKHVQYGNVPAVSAAVKGLR 2007
+KC C + H + L+KHV AA KG +
Sbjct: 662 -------------------HKCDMCDKGFHRP-----SELKKHV---------AAHKGKK 688
Query: 2008 SHERSHL-------------ALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPF 2054
H+ H L++ T++ + C+ C + L +HM+TH G K +
Sbjct: 689 MHQCRHCDFKIADPFVLSRHILSVHTKDLPFRCKRCRKGFRQQSELKKHMKTHSGR-KVY 747
Query: 2055 RCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVHGKALTLP 2113
+C+ C + ++ S K H++ H ++ ++C +C S+ +H ++ H K + LP
Sbjct: 748 QCEYCEYSTTDASGFKRHVISIHTKDYPHRCEYCKKGFRRPSEKNQHIMR-HHKEVGLP 805
Score = 57.4 bits (137), Expect = 2e-07
Identities = 95/463 (20%), Positives = 147/463 (31%), Gaps = 113/463 (24%)
Query: 1468 TPYQCTVCQSEYNNLHGLLTHYGKKHPGMKVKAADFAQDIDINPGAVYKCRHCPYINTRI 1527
T Y C +C ++ + G L + K HP K Y+C C Y +
Sbjct: 423 TVYPCMICGKKFKS-RGFLKRHMKNHPEHLAKKK-------------YRCTDCDYTTNKK 468
Query: 1528 HGVLTHYQKRHPSIKVTAEDFVHDVEQSADISQNDVEETSRIFKQGYGA---YRCKLCPY 1584
+ H + + K AE + E S T ++ + GA ++CK C Y
Sbjct: 469 ISLHNHLESHKLTSK--AEKAIECDECGKHFSHAGALFTHKMVHKEKGANKMHKCKFCEY 526
Query: 1585 THGTLEKLKIHYEKYH--NQPEFDVFSQSPPKLPVPLEPEMTTEVSPSQVSITEEEVGEE 1642
L H H N P V + P L+ M GE+
Sbjct: 527 ETAEQGLLNRHLLAVHSKNFPHICVECGKGFRHPSELKKHMRIHT------------GEK 574
Query: 1643 PVSTSHFSTSHLVSHTVFRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCALC 1702
P ++CQ C+Y + + H + KH+ K FKC +C
Sbjct: 575 P----------------YQCQYCEYRSADSSNLKTHVKTKHS--------KEMPFKCDIC 610
Query: 1703 AYTNPIRKGLAAHYQKRHDIDAYY-THCLAASRTISDKPNKVIIPSPPKDDSPQLSEELR 1761
T K + H + + HC S SD +I S D P
Sbjct: 611 LLTFSDTKEVQQHALIHQESKTHQCLHCDHKSSNSSDLKRHII--SVHTKDYPH------ 662
Query: 1762 RAVEKKKCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGYFTAVYADEHEKPTLM 1821
KC +C + F + + ++ H G KK H + + A P ++
Sbjct: 663 ------KCDMCD-KGFHRPSELKKHVAAHKG---KKMHQCRHCDFKIA-------DPFVL 705
Query: 1822 EEEERGNFEKAEVEGEAQEIEWLPFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIIL 1881
K LPFRC +C K F L H H R
Sbjct: 706 SRHILSVHTKD-----------LPFRCKRCRK-GFRQQSELKKHMKTHSGR--------- 744
Query: 1882 GNGPRLQNSTYQCKHCDSKLQSTAELTSH-LNIHNEEFQKRAK 1923
YQC++C+ + H ++IH +++ R +
Sbjct: 745 --------KVYQCEYCEYSTTDASGFKRHVISIHTKDYPHRCE 779
Score = 47.8 bits (112), Expect = 1e-04
Identities = 28/111 (25%), Positives = 44/111 (39%), Gaps = 5/111 (4%)
Query: 83 GGYYGHSPGYYGQHIAANPKPTNKFFQCKFCVRYFRSKNLLIEHTRKVHGAQ----AEGS 138
G ++ H+ + + K NK +CKFC + LL H VH
Sbjct: 494 GKHFSHAGALFTHKMVHKEKGANKMHKCKFCEYETAEQGLLNRHLLAVHSKNFPHICVEC 553
Query: 139 SSGPPVPGSLNYNIMMHEGFGKVFSCQFCTYKSPRRARIIKHQKMYHKNNL 189
G P L ++ +H G K + CQ+C Y+S + + H K H +
Sbjct: 554 GKGFRHPSELKKHMRIHTG-EKPYQCQYCEYRSADSSNLKTHVKTKHSKEM 603
Score = 45.1 bits (105), Expect = 9e-04
Identities = 68/371 (18%), Positives = 127/371 (34%), Gaps = 61/371 (16%)
Query: 1195 CQHCDYGNRTVKGVLIHYQKKHRDFKANADVIRQHTATIRSLCDRNQKKPASC-VLVSPS 1253
C CDY T K + +H + + A+ + CD K + L +
Sbjct: 458 CTDCDY--TTNKKISLHNHLESHKLTSKAEKAIE--------CDECGKHFSHAGALFTHK 507
Query: 1254 NLERDKTKLRALKCRQCSYTSPYFYALRKHI----KKDHPALKATV------TSIMRWAF 1303
+ ++K + KC+ C Y + L +H+ K+ P + S ++
Sbjct: 508 MVHKEKGANKMHKCKFCEYETAEQGLLNRHLLAVHSKNFPHICVECGKGFRHPSELKKHM 567
Query: 1304 LDGLIEAGYHCEWCIYSHTEPNGLLLHYQRRHPEHYVDYTYMATKLWAGPDPSPPSLTMP 1363
E Y C++C Y + + L H + +H + + ++ +
Sbjct: 568 RIHTGEKPYQCQYCEYRSADSSNLKTHVKTKHSKEMPFKCDICLLTFSDTKEVQQHALIH 627
Query: 1364 AEAKTYRCRDCVFEAVSIWDITNHYQAFHPWAMNGDESVLLDIIKEKDAVEKPILSSEEL 1423
E+KT++C C ++ + D+ H + H KD K + +
Sbjct: 628 QESKTHQCLHCDHKSSNSSDLKRHIISVH----------------TKDYPHKCDMCDKGF 671
Query: 1424 AGPVNCENSIPTPFPEQEAECPE-DARLSPEKSLQLASANPAISSTPYQCTVCQSEYNNL 1482
P + + ++ +C D +++ L + P++C C+ +
Sbjct: 672 HRPSELKKHVAAHKGKKMHQCRHCDFKIADPFVLSRHILSVHTKDLPFRCKRCRKGFRQQ 731
Query: 1483 HGLLTHYGKKHPGMKVKAADFAQDIDINPGAVYKCRHCPYINTRIHGVLTHYQKRHPSIK 1542
L H K H G K VY+C +C Y T G KRH I
Sbjct: 732 SELKKHM-KTHSGRK----------------VYQCEYCEYSTTDASGF-----KRH-VIS 768
Query: 1543 VTAEDFVHDVE 1553
+ +D+ H E
Sbjct: 769 IHTKDYPHRCE 779
Score = 41.6 bits (96), Expect = 0.010
Identities = 120/659 (18%), Positives = 226/659 (34%), Gaps = 154/659 (23%)
Query: 714 EDAVINVEDDEEEEEDNEVEIEVELDREEEPTEPIIEVPTSFSAQQIWVRDTSEPQKEPN 773
ED + D E E +N+ +E+ LD+ I VP + V D+ ++ N
Sbjct: 262 EDDLGGTVDIVESEPENDHGVEL-LDQNSS-----IRVPRE-KMVYMTVNDSQPEDEDLN 314
Query: 774 FRNITHDYNATNGAEIELTLSEDEEDYYGSSTNLKDHQVSNTALLNTQTPI-----YGTE 828
I + +E+ + E++ ++ + + Q+ + + T PI YG
Sbjct: 315 VAEIADE------VYMEVIVGEEDAAAAAAAAAVHEQQMDDNEI-KTFMPIAWAAAYGNN 367
Query: 829 HNSENTDFGDSGRLYYCKHCDFNNKSARSVSTHYQRMHPYIKFSFRYILDPNDHS-AVYR 887
+ G + L + + A+ +R ++ I+ P+ H VY
Sbjct: 368 SDGIENRNGTASALLHIDESAGLGRLAKQKPKKRRRPDSR-QYQTAIIIGPDGHPLTVYP 426
Query: 888 CLECYIDYTNFEDLQQHYGEHHPEAMNVLNFDHSDLIYRCRFCSYTSPNVRSLMPHYQRM 947
C+ C + + L++H ++HPE + + YRC C YT+ SL H +
Sbjct: 427 CMICGKKFKSRGFLKRHM-KNHPEHL-------AKKKYRCTDCDYTTNKKISLHNHLESH 478
Query: 948 HPTVKINNAM--------------IFSSYVVEQQEGLNTESQTLREILNSAPKNMATSTP 993
T K A+ +F+ +V +++G N + +A + +
Sbjct: 479 KLTSKAEKAIECDECGKHFSHAGALFTHKMVHKEKGANKMHKCKFCEYETAEQGLLNRH- 537
Query: 994 VARGGGLPATFNKNTP-------KTFTPECENQKDPLVNT-VVVYDCDVCSFASPNMHSV 1045
L A +KN P K F E +K ++T Y C C + S + ++
Sbjct: 538 ------LLAVHSKNFPHICVECGKGFRHPSELKKHMRIHTGEKPYQCQYCEYRSADSSNL 591
Query: 1046 LVHYQKKHPEEKASYFRIQKTMRMVSVDRGSALSQLSFEVGAPMSPKMSNMGSPPPPQPP 1105
H + KH +E F+ + S + L +
Sbjct: 592 KTHVKTKHSKEMP--FKCDICLLTFSDTKEVQQHALIHQ--------------------- 628
Query: 1106 PPDLSTELYYCKHCSYSNRSVVGVLVHYQKRHPEIKVTAKYIRQAPPTAAMMRGVEGPQG 1165
++ + C HC + + + + KRH + + + + P M +G
Sbjct: 629 ----ESKTHQCLHCDHKSSNSSDL-----KRH----IISVHTKDYPHKCDMC-----DKG 670
Query: 1166 SPRPPAPIQQLNRSSSERDGPPVENEMFFCQHCDYGNRTVKGVLIHYQKKHRDFKANADV 1225
RP +L + + G +M C+HCD+ K F + +
Sbjct: 671 FHRP----SELKKHVAAHKG----KKMHQCRHCDF-------------KIADPFVLSRHI 709
Query: 1226 IRQHTATIRSLCDRNQKKPASCVLVSPSNLE---RDKTKLRALKCRQCSYTSPYFYALRK 1282
+ HT + C R +K S L+ + + + +C C Y++ ++
Sbjct: 710 LSVHTKDLPFRCKRCRKG-----FRQQSELKKHMKTHSGRKVYQCEYCEYSTTDASGFKR 764
Query: 1283 HI----KKDHPALKATVTSIMRWAFLDGLIEAGYHCEWCIYSHTEPNGLLLHYQRRHPE 1337
H+ KD+P + CE+C P+ H R H E
Sbjct: 765 HVISIHTKDYP----------------------HRCEYCKKGFRRPSEKNQHIMRHHKE 801
Score = 37.4 bits (85), Expect = 0.19
Identities = 38/151 (25%), Positives = 61/151 (40%), Gaps = 17/151 (11%)
Query: 2299 VFRCDKCTFTCSSDESLQQHIEKHNE---LKPYKCQLCYYETKHTEELDSHLRDEHKVSR 2355
V+ C C S L++H++ H E K Y+C C Y T L +HL + HK++
Sbjct: 424 VYPCMICGKKFKSRGFLKRHMKNHPEHLAKKKYRCTDCDYTTNKKISLHNHL-ESHKLTS 482
Query: 2356 NFELVGRVNLDQLEQ--------MKEKMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAA 2407
E + D+ + KM + + E E + H A
Sbjct: 483 KAEKA--IECDECGKHFSHAGALFTHKMVHKEKGANKMHKCKFCEYETAEQGLLNRHLLA 540
Query: 2408 LNTEKRFP--CEFCGRAFSQGSEWERHVLRH 2436
+++ K FP C CG+ F SE ++H+ H
Sbjct: 541 VHS-KNFPHICVECGKGFRHPSELKKHMRIH 570
Score = 37.4 bits (85), Expect = 0.19
Identities = 63/359 (17%), Positives = 115/359 (32%), Gaps = 65/359 (18%)
Query: 1266 KCRQCSYTSPYFYALRKHIKKDHPALKATVT----------SIMRWAFLDGLI--EAG-- 1311
+C C YT+ +L H++ KA S F ++ E G
Sbjct: 457 RCTDCDYTTNKKISLHNHLESHKLTSKAEKAIECDECGKHFSHAGALFTHKMVHKEKGAN 516
Query: 1312 --YHCEWCIYSHTEPNGLLLHYQRRHPEHYVDYTYMATKLWAGPDPSPPSLTMPAEAKTY 1369
+ C++C Y E L H H +++ K + P + + K Y
Sbjct: 517 KMHKCKFCEYETAEQGLLNRHLLAVHSKNFPHICVECGKGFRHPSELKKHMRIHTGEKPY 576
Query: 1370 RCRDCVFEAVSIWDITNHYQAFHPWAMNGDESVLLDIIKEKDAVEKPILSSEELAGPVNC 1429
+C+ C + + ++ H + H M + L + V++ L +E
Sbjct: 577 QCQYCEYRSADSSNLKTHVKTKHSKEMPFKCDICLLTFSDTKEVQQHALIHQESK----- 631
Query: 1430 ENSIPTPFPEQEAECPEDARLSPEKSLQLASANPAISSTPYQCTVCQSEYNNLHGLLTHY 1489
Q C + S + + S + P++C +C ++ L H
Sbjct: 632 --------THQCLHCDHKSSNSSDLKRHIISVH--TKDYPHKCDMCDKGFHRPSELKKHV 681
Query: 1490 GKKHPGMKVKAADFAQDIDINPGAVYKCRHC------PYINTRIHGVLTHYQKRHPSIKV 1543
H G K +++CRHC P++ +R H + H + K
Sbjct: 682 A-AHKGKK----------------MHQCRHCDFKIADPFVLSR-HILSVHTKDLPFRCKR 723
Query: 1544 TAEDFVHDVEQSADISQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQ 1602
+ F E + + G Y+C+ C Y+ K H H +
Sbjct: 724 CRKGFRQQSELKKHMKTH----------SGRKVYQCEYCEYSTTDASGFKRHVISIHTK 772
Score = 35.8 bits (81), Expect = 0.54
Identities = 38/199 (19%), Positives = 69/199 (34%), Gaps = 23/199 (11%)
Query: 5 QCDGCDFRAPSYEDLKAHIQDVHT------------AFLQPTDVAEDNV--NELRCGSVN 50
QC C++R+ +LK H++ H+ F +V + + E +
Sbjct: 577 QCQYCEYRSADSSNLKTHVKTKHSKEMPFKCDICLLTFSDTKEVQQHALIHQESKTHQCL 636
Query: 51 ASNQTEVEFSSIKDEFAIAEDLSGQNATSLGTGGYYGHSPGYYGQHIAANPKPTNKFFQC 110
+ S +K + + G+ H P +H+AA+ K QC
Sbjct: 637 HCDHKSSNSSDLKRHIISVHTKDYPHKCDMCDKGF--HRPSELKKHVAAHKG--KKMHQC 692
Query: 111 KFCVRYFRSKNLLIEHTRKVHGA----QAEGSSSGPPVPGSLNYNIMMHEGFGKVFSCQF 166
+ C +L H VH + + G L ++ H G KV+ C++
Sbjct: 693 RHCDFKIADPFVLSRHILSVHTKDLPFRCKRCRKGFRQQSELKKHMKTHSG-RKVYQCEY 751
Query: 167 CTYKSPRRARIIKHQKMYH 185
C Y + + +H H
Sbjct: 752 CEYSTTDASGFKRHVISIH 770
Score = 35.0 bits (79), Expect = 0.93
Identities = 50/245 (20%), Positives = 89/245 (36%), Gaps = 37/245 (15%)
Query: 270 VKILSSLRQQQEGTNLPDVPNKSAPSPTSNSTYLTMNAASREIPNTTVSNFRGSMGNS-I 328
V I+ S + G L D N S P Y+T+N + E + V+ + I
Sbjct: 269 VDIVESEPENDHGVELLD-QNSSIRVPREKMVYMTVNDSQPEDEDLNVAEIADEVYMEVI 327
Query: 329 MRPNSSASKFSPMSYPQMKPKSPHNSGLVNLTERSRYGMTDMTNSSADLETNSMLNDSSS 388
+ +A+ + + + + + + + YG N+S +E N + +
Sbjct: 328 VGEEDAAAAAAAAAVHEQQMDDNEIKTFMPIAWAAAYG-----NNSDGIE-----NRNGT 377
Query: 389 DEELNEIDSENGLSAMDHQ---------TSGLSAEQLMGSDGNKLLETKGIPFRRFMNRF 439
L ID GL + Q + ++G DG+ L +
Sbjct: 378 ASALLHIDESAGLGRLAKQKPKKRRRPDSRQYQTAIIIGPDGHPLTV------------Y 425
Query: 440 QCPFCPFLTMHRRSISRHIENI--HLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTGTTS 497
C C R + RH++N HL+ K Y+C +C +T + L H + H T+
Sbjct: 426 PCMICGKKFKSRGFLKRHMKNHPEHLAKKK--YRCTDCDYTTNKKISLHNHLESHKLTSK 483
Query: 498 DWDAV 502
A+
Sbjct: 484 AEKAI 488
Score = 35.0 bits (79), Expect = 0.93
Identities = 73/366 (19%), Positives = 119/366 (32%), Gaps = 51/366 (13%)
Query: 1326 GLLLHYQRRHPEHYVDYTYMAT--------KLWAGPDPSPPSLTMPAEAKTYRCRDCVFE 1377
G L + + HPEH Y T K+ LT AE K C +C
Sbjct: 438 GFLKRHMKNHPEHLAKKKYRCTDCDYTTNKKISLHNHLESHKLTSKAE-KAIECDECGKH 496
Query: 1378 AVSIWDITNHYQAFHPWAMNGDESVLLDIIKEKDAVEKPILSSEELAGPVNCENSIPTPF 1437
+ H N E + E+ +L+ LA V+ +N F
Sbjct: 497 FSHAGALFTHKMVHKEKGANKMHKCKFC---EYETAEQGLLNRHLLA--VHSKN-----F 546
Query: 1438 PEQEAECPEDARLSPEKSLQLASANPAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPGMK 1497
P EC + R E + PYQC C+ + L TH KH
Sbjct: 547 PHICVECGKGFRHPSELKKHMRIHT---GEKPYQCQYCEYRSADSSNLKTHVKTKHS--- 600
Query: 1498 VKAADFAQDIDINPGAVYKCRHCPYINTRIHGVLTHYQKRHPSIKVTAEDFVHDVEQSAD 1557
K F DI + + K + H ++ K H + H S+D
Sbjct: 601 -KEMPFKCDICLLTFSDTK-------EVQQHALIHQESKTHQCLHCD-----HKSSNSSD 647
Query: 1558 ISQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHY-----EKYHNQPEFDVFSQSP 1612
+ ++ + ++ + ++C +C +LK H +K H D P
Sbjct: 648 LKRHIISVHTKDYP-----HKCDMCDKGFHRPSELKKHVAAHKGKKMHQCRHCDFKIADP 702
Query: 1613 PKLPVPLEPEMTTEVSPSQVSITEEEVGEEPVSTSHFSTSHLVSHTVFRCQLCKYFCSTR 1672
L + T ++ P + + ++ H T V++C+ C+Y +
Sbjct: 703 FVLSRHILSVHTKDL-PFRCKRCRKGFRQQSELKKHMKTHS--GRKVYQCEYCEYSTTDA 759
Query: 1673 KGIARH 1678
G RH
Sbjct: 760 SGFKRH 765
Score = 34.3 bits (77), Expect = 1.6
Identities = 18/81 (22%), Positives = 34/81 (41%), Gaps = 2/81 (2%)
Query: 439 FQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTGTTSD 498
+QC +C + + ++ H++ H K +KCD C T + ++ H H + +
Sbjct: 576 YQCQYCEYRSADSSNLKTHVKTKH--SKEMPFKCDICLLTFSDTKEVQQHALIHQESKTH 633
Query: 499 WDAVNSQSESISSSLNEGVVS 519
S SS L ++S
Sbjct: 634 QCLHCDHKSSNSSDLKRHIIS 654
Score = 33.9 bits (76), Expect = 2.1
Identities = 36/166 (21%), Positives = 60/166 (36%), Gaps = 35/166 (21%)
Query: 1189 ENEMFFCQHCDYGNRTVKGVLIHYQKKH-RDFKANADV----------IRQHTATIRSLC 1237
E++ C HCD+ + + H H +D+ D+ +++H A +
Sbjct: 629 ESKTHQCLHCDHKSSNSSDLKRHIISVHTKDYPHKCDMCDKGFHRPSELKKHVAAHKGK- 687
Query: 1238 DRNQKKPASCVLVSPSNLERD----KTKLRALKCRQCSYTSPYFYALRKHIKKDHPALKA 1293
+Q + + P L R TK +C++C L+KH+K H K
Sbjct: 688 KMHQCRHCDFKIADPFVLSRHILSVHTKDLPFRCKRCRKGFRQQSELKKHMKT-HSGRKV 746
Query: 1294 TVTSIMRWAFLDGLIEAGYHCEWCIYSHTEPNGLLLHYQRRHPEHY 1339
Y CE+C YS T+ +G H H + Y
Sbjct: 747 ------------------YQCEYCEYSTTDASGFKRHVISIHTKDY 774
Score = 32.3 bits (72), Expect = 6.0
Identities = 16/55 (29%), Positives = 27/55 (49%), Gaps = 2/55 (3%)
Query: 440 QCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTG 494
+C FC + T + ++RH+ +H K + C EC + +L H + HTG
Sbjct: 520 KCKFCEYETAEQGLLNRHLLAVH--SKNFPHICVECGKGFRHPSELKKHMRIHTG 572
>gi|40255145 zinc finger protein 555 [Homo sapiens]
Length = 628
Score = 97.8 bits (242), Expect = 1e-19
Identities = 119/517 (23%), Positives = 176/517 (34%), Gaps = 144/517 (27%)
Query: 1845 PFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQST 1904
P++C +C + ++S L MH + NG R Y CK C T
Sbjct: 171 PYQCQECGQ-AYSCRSHLRMH-------------VRTNNGER----PYVCKLCGKTFPRT 212
Query: 1905 AELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQ--ERPFGHLEEVPKIKE 1962
+ L H+ IH E K+ AF DF H E P
Sbjct: 213 SSLNRHVRIHTAEKTYECKQ-------------CGKAFIDFSSLTSHLRSHTGEKP---- 255
Query: 1963 RKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVPAVSAAVKGLRSHERSHLALAMFTRE 2022
YKCK C K Y + R H +H T E
Sbjct: 256 -----YKCKEC--------------GKAFSYSST---------FRRHTITH------TGE 281
Query: 2023 DKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHA 2082
Y C+ C+ ++ RHM +H G KP +CK C SY+S + H++ H GE
Sbjct: 282 KPYKCKECAEAFSYSSTFRRHMISHTG-EKPHKCKECGEAFSYSSAFRRHMI-THTGEKP 339
Query: 2083 YKCSWCSFSTMTISQLKEHSLKVH-----------GKALTLPRPRIVSLLSSHSHHSSQK 2131
Y+C C + + + + H ++H GK P+ S H +K
Sbjct: 340 YECKQCGKTFIYLQSFRRHE-RIHTGEKPYECKQCGKTFIYPQ----SFRRHERTHGGEK 394
Query: 2132 ATPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVL 2191
P + Q + + R + RV E
Sbjct: 395 -----------------PYECNQCGKAFSHPSSFRGHMRV-------------HTGEKPY 424
Query: 2192 HCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGP 2251
C+ C + + S+R+H R H +K ++CK C + F HV PE+
Sbjct: 425 ECKQCGKTFNWPISLRKHMR-THTREKPYECKQCGKAFSLSACFREHVRMH----PED-- 477
Query: 2252 KDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRCDKCTFTCSS 2311
K C LC + HI L + R ++ +++C +C S
Sbjct: 478 KSYECKLC------GKAFYCHISLQKHMR------------RHTAEKLYKCKQCGTAFSW 519
Query: 2312 DESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLR 2348
E LQQH+ H KPY+C+ C K L H+R
Sbjct: 520 PELLQQHVRTHTVEKPYECKECGKVFKWPSSLPIHMR 556
Score = 96.7 bits (239), Expect = 3e-19
Identities = 109/464 (23%), Positives = 176/464 (37%), Gaps = 67/464 (14%)
Query: 2009 HERSHLA--LAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYN 2066
H R+ L + + T Y CQ C + R +L H++T++G +P+ CKLC
Sbjct: 154 HRRTSLKSPITVHTGHKPYQCQECGQAYSCRSHLRMHVRTNNG-ERPYVCKLCGKTFPRT 212
Query: 2067 SRLKTHILKAHAGEHAYKCSWC-----SFSTMTISQLKEHS------LKVHGKALTLPRP 2115
S L H+ + H E Y+C C FS++T S L+ H+ K GKA +
Sbjct: 213 SSLNRHV-RIHTAEKTYECKQCGKAFIDFSSLT-SHLRSHTGEKPYKCKECGKAFSYS-- 268
Query: 2116 RIVSLLSSHS-HHSSQKATPAEEVEDSND----------SSYSEPPDVQQQLNHYQSAAL 2164
S H+ H+ +K +E ++ S E P ++ S +
Sbjct: 269 ---STFRRHTITHTGEKPYKCKECAEAFSYSSTFRRHMISHTGEKPHKCKECGEAFSYSS 325
Query: 2165 ARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKD 2224
A ++ E C+ C + Y+QS RRH R H G+K ++CK
Sbjct: 326 AFRRHMIT------------HTGEKPYECKQCGKTFIYLQSFRRHER-IHTGEKPYECKQ 372
Query: 2225 CSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPI 2284
C + +F H E H G K C C + + H+ +H E+
Sbjct: 373 CGKTFIYPQSFRRH-ERTHG-----GEKPYECNQCGKAFSHPSSFRGHMRVHTGEKPYEC 426
Query: 2285 EVC----------RSKLSKYLQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCY 2334
+ C R + + + + C +C S ++H+ H E K Y+C+LC
Sbjct: 427 KQCGKTFNWPISLRKHMRTHTREKPYECKQCGKAFSLSACFREHVRMHPEDKSYECKLCG 486
Query: 2335 YETKHTEELDSHLR--DEHKVSRNFELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSK 2392
L H+R K+ + + + +L Q + + E KE K
Sbjct: 487 KAFYCHISLQKHMRRHTAEKLYKCKQCGTAFSWPELLQQHVRTHTVEKPYECKECGKVFK 546
Query: 2393 AEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRH 2436
+ H EK + C+ CG+AF+ S RHV H
Sbjct: 547 WPSSLPIHMRLH----TGEKPYQCKHCGKAFNCSSSLRRHVRIH 586
Score = 96.3 bits (238), Expect = 3e-19
Identities = 111/463 (23%), Positives = 166/463 (35%), Gaps = 114/463 (24%)
Query: 1891 TYQCKHCDSKLQSTAELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERP 1950
TY+CK C + LTSHL H E K K +E K +++ +
Sbjct: 227 TYECKQCGKAFIDFSSLTSHLRSHTGE--KPYKCKECGKAF---------SYSSTFRRHT 275
Query: 1951 FGHLEEVPKIKERKVVGYKCKFCVEVHPTLRAICNHLRKHV--------QYGNVPAVSAA 2002
H E P YKCK C E H+ H + G + S+A
Sbjct: 276 ITHTGEKP---------YKCKECAEAFSYSSTFRRHMISHTGEKPHKCKECGEAFSYSSA 326
Query: 2003 VKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFK 2062
R H +H T E Y C+ C + + RH + H G KP+ CK C
Sbjct: 327 ---FRRHMITH------TGEKPYECKQCGKTFIYLQSFRRHERIHTGE-KPYECKQCGKT 376
Query: 2063 SSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVH-----------GKALT 2111
Y + H + H GE Y+C+ C + S + H ++VH GK
Sbjct: 377 FIYPQSFRRHE-RTHGGEKPYECNQCGKAFSHPSSFRGH-MRVHTGEKPYECKQCGKTFN 434
Query: 2112 LPRPRIVSLLSSHSHHSSQKATPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNSRV 2171
P +SL H+ +K P + +Q + +A R + R+
Sbjct: 435 WP----ISLRKHMRTHTREK-----------------PYECKQCGKAFSLSACFREHVRM 473
Query: 2172 SPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGF 2231
P E K+ C+ C + S+++H R +H +KL+KCK C +
Sbjct: 474 HP----------EDKS---YECKLCGKAFYCHISLQKHMR-RHTAEKLYKCKQCGTAFSW 519
Query: 2232 KSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKL 2291
HV P E C C K+ ++ H+ LH E+
Sbjct: 520 PELLQQHVRTHTVEKPYE------CKECGKVFKWPSSLPIHMRLHTGEKP---------- 563
Query: 2292 SKYLQGVVFRCDKC--TFTCSSDESLQQHIEKHNELKPYKCQL 2332
++C C F CSS SL++H+ H K YKC +
Sbjct: 564 --------YQCKHCGKAFNCSS--SLRRHVRIHTTEKQYKCNV 596
Score = 95.5 bits (236), Expect = 6e-19
Identities = 108/480 (22%), Positives = 175/480 (36%), Gaps = 104/480 (21%)
Query: 1968 YKCKFCVEVHPTLRAICNHLRKHVQYGNV--PAVSAA-------VKGLRSHERSHLALAM 2018
Y+C+ C + + + +HLR HV+ N P V L H R H
Sbjct: 172 YQCQECGQAY----SCRSHLRMHVRTNNGERPYVCKLCGKTFPRTSSLNRHVRIH----- 222
Query: 2019 FTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHA 2078
T E Y C+ C +L H+++H G KP++CK C SY+S + H + H
Sbjct: 223 -TAEKTYECKQCGKAFIDFSSLTSHLRSHTGE-KPYKCKECGKAFSYSSTFRRHTI-THT 279
Query: 2079 GEHAYKCSWCSFSTMTISQLKEHSLKVHGKALTLPRPRIVSLLSSHSHHSSQKATPAEEV 2138
GE YKC C+ + S + H + H+ +K +E
Sbjct: 280 GEKPYKCKECAEAFSYSSTFRRHMIS----------------------HTGEKPHKCKEC 317
Query: 2139 EDSNDSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEF 2198
++ Y SA + P C+ C
Sbjct: 318 GEAFS---------------YSSAFRRHMITHTGEKPYE---------------CKQCGK 347
Query: 2199 SSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPL 2258
+ Y+QS RRH R H G+K ++CK C + +F H E H G K C
Sbjct: 348 TFIYLQSFRRHERI-HTGEKPYECKQCGKTFIYPQSFRRH-ERTHG-----GEKPYECNQ 400
Query: 2259 CLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRCDKCTFTCSSDESLQQH 2318
C + + H+ +H E+ + C +C T + SL++H
Sbjct: 401 CGKAFSHPSSFRGHMRVHTGEKP------------------YECKQCGKTFNWPISLRKH 442
Query: 2319 IEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFE--LVGRVNLDQLEQMKEKME 2376
+ H KPY+C+ C + H+R H +++E L G+ + K M
Sbjct: 443 MRTHTREKPYECKQCGKAFSLSACFREHVR-MHPEDKSYECKLCGKAFYCHISLQKH-MR 500
Query: 2377 SSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRH 2436
+++ K ++ + EL++ H EK + C+ CG+ F S H+ H
Sbjct: 501 RHTAEKLYKCKQCGTAFSWPELLQ--QHVRTHTVEKPYECKECGKVFKWPSSLPIHMRLH 558
Score = 84.0 bits (206), Expect = 2e-15
Identities = 100/464 (21%), Positives = 166/464 (35%), Gaps = 80/464 (17%)
Query: 2028 QYCSFVSAFRH---NLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYK 2084
+Y ++ F H +L + H GH KP++C+ C S S L+ H+ + + GE Y
Sbjct: 144 EYNTYGKVFMHRRTSLKSPITVHTGH-KPYQCQECGQAYSCRSHLRMHV-RTNNGERPYV 201
Query: 2085 CSWCSFSTMTISQLKEHSLKVHGKALTLPRPRIVSLLSSHSHHSSQKATPAEEVEDSNDS 2144
C C GK PR SL H+++K ++ +
Sbjct: 202 CKLC------------------GKTF----PRTSSLNRHVRIHTAEKTYECKQCGKAFI- 238
Query: 2145 SYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQ 2204
D +H +S E C+ C + Y
Sbjct: 239 ------DFSSLTSHLRS-----------------------HTGEKPYKCKECGKAFSYSS 269
Query: 2205 SIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTK 2264
+ RRH H G+K +KCK+C+ + S F H+ + G K +C C
Sbjct: 270 TFRRH-TITHTGEKPYKCKECAEAFSYSSTFRRHM------ISHTGEKPHKCKECGEAFS 322
Query: 2265 YKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGV-----------VFRCDKCTFTCSSDE 2313
Y H++ H E+ + C K YLQ + C +C T +
Sbjct: 323 YSSAFRRHMITHTGEKPYECKQC-GKTFIYLQSFRRHERIHTGEKPYECKQCGKTFIYPQ 381
Query: 2314 SLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFELVGRVNLDQLEQMKE 2373
S ++H H KPY+C C H H+R H + +E
Sbjct: 382 SFRRHERTHGGEKPYECNQCGKAFSHPSSFRGHMR-VHTGEKPYECKQCGKTFNWPISLR 440
Query: 2374 KMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHV 2433
K + + ++ E + KA F +H +K + C+ CG+AF ++H+
Sbjct: 441 KHMRTHTREKPYECKQCGKAFSLSAC-FREHVRMHPEDKSYECKLCGKAFYCHISLQKHM 499
Query: 2434 LRH-GMALNDTKQVSREEIHPKEIMENSVKMPSIEEKEDDEAIG 2476
RH L KQ P E+++ V+ ++E+ + + G
Sbjct: 500 RRHTAEKLYKCKQCGTAFSWP-ELLQQHVRTHTVEKPYECKECG 542
Score = 57.0 bits (136), Expect = 2e-07
Identities = 40/175 (22%), Positives = 73/175 (41%), Gaps = 12/175 (6%)
Query: 2264 KYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRCDKCTFTCSSDESLQQHIEKHN 2323
+Y+ N + +HR + +S ++ + ++C +C S L+ H+ +N
Sbjct: 142 QYEYNTYGKVFMHRRTSL------KSPITVHTGHKPYQCQECGQAYSCRSHLRMHVRTNN 195
Query: 2324 ELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFEL--VGRVNLDQLEQMKEKMESSSSD 2381
+PY C+LC T L+ H+R H + +E G+ +D + + S + +
Sbjct: 196 GERPYVCKLCGKTFPRTSSLNRHVR-IHTAEKTYECKQCGKAFID-FSSLTSHLRSHTGE 253
Query: 2382 DEDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRH 2436
K +E F H EK + C+ C AFS S + RH++ H
Sbjct: 254 KPYKCKECGKAFSYSS--TFRRHTITHTGEKPYKCKECAEAFSYSSTFRRHMISH 306
Score = 55.8 bits (133), Expect = 5e-07
Identities = 65/309 (21%), Positives = 105/309 (33%), Gaps = 48/309 (15%)
Query: 2149 PPDVQQ-QLNHYQSAALARNNSRVSPV-------PLSGAAAGTEQKTEAVLH-------- 2192
PP V+Q + N Y + R S SP+ P G + L
Sbjct: 137 PPGVKQYEYNTYGKVFMHRRTSLKSPITVHTGHKPYQCQECGQAYSCRSHLRMHVRTNNG 196
Query: 2193 -----CEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVP 2247
C+ C + S+ RH R H +K ++CK C S+ T H+ +
Sbjct: 197 ERPYVCKLCGKTFPRTSSLNRHVRI-HTAEKTYECKQCGKAFIDFSSLTSHLRS------ 249
Query: 2248 EEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRCDKCTF 2307
G K +C C Y H + H E+ ++C +C
Sbjct: 250 HTGEKPYKCKECGKAFSYSSTFRRHTITHTGEKP------------------YKCKECAE 291
Query: 2308 TCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFELVGRVNLDQ 2367
S + ++H+ H KP+KC+ C ++ H+ H + +E
Sbjct: 292 AFSYSSTFRRHMISHTGEKPHKCKECGEAFSYSSAFRRHM-ITHTGEKPYECKQCGKTFI 350
Query: 2368 LEQMKEKMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGS 2427
Q + E + ++ E + K F H EK + C CG+AFS S
Sbjct: 351 YLQSFRRHERIHTGEKPYECKQCGKTFIYP-QSFRRHERTHGGEKPYECNQCGKAFSHPS 409
Query: 2428 EWERHVLRH 2436
+ H+ H
Sbjct: 410 SFRGHMRVH 418
Score = 32.3 bits (72), Expect = 6.0
Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 12/85 (14%)
Query: 1846 FRCIKCFKLSFSTAELLCMHYTDH------HSRDLKRDFIILGNGP---RLQNST--YQC 1894
++C +C +FS ELL H H ++ + F + P RL YQC
Sbjct: 508 YKCKQC-GTAFSWPELLQQHVRTHTVEKPYECKECGKVFKWPSSLPIHMRLHTGEKPYQC 566
Query: 1895 KHCDSKLQSTAELTSHLNIHNEEFQ 1919
KHC ++ L H+ IH E Q
Sbjct: 567 KHCGKAFNCSSSLRRHVRIHTTEKQ 591
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.130 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 113,194,421
Number of Sequences: 37866
Number of extensions: 6361357
Number of successful extensions: 186237
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1611
Number of HSP's successfully gapped in prelim test: 1027
Number of HSP's that attempted gapping in prelim test: 50603
Number of HSP's gapped (non-prelim): 70008
length of query: 2506
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2387
effective length of database: 13,741,464
effective search space: 32800874568
effective search space used: 32800874568
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.