Search of human proteins with 217416356

Search of human proteins with 217416356

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|217416356 transmembrane protein 194B [Homo sapiens]
         (417 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|217416356 transmembrane protein 194B [Homo sapiens]                862   0.0  
gi|195972881 transmembrane protein 194A isoform a [Homo sapiens]      262   5e-70
gi|195972879 transmembrane protein 194A isoform b [Homo sapiens]      213   3e-55
gi|148612863 transient receptor potential cation channel, subfam...    32   0.82 
gi|26051223 sperm-associated cation channel 2 isoform 2 [Homo sa...    32   1.4  
gi|16876443 sperm-associated cation channel 2 isoform 1 [Homo sa...    32   1.4  
gi|4557803 Niemann-Pick disease, type C1 precursor [Homo sapiens]      31   2.4  
gi|25282391 nurim [Homo sapiens]                                       30   4.1  
gi|26051227 sperm-associated cation channel 2 isoform 4 [Homo sa...    30   5.3  
gi|4506813 sodium channel, voltage-gated, type IX, alpha [Homo s...    29   6.9  
gi|4507011 glucose transporter 4 [Homo sapiens]                        29   9.0  
gi|9507173 taste receptor T2R5 [Homo sapiens]                          29   9.0  

>gi|217416356 transmembrane protein 194B [Homo sapiens]
          Length = 417

 Score =  862 bits (2226), Expect = 0.0
 Identities = 417/417 (100%), Positives = 417/417 (100%)

Query: 1   MGPRQGRWWLLLWLPPLATLPVRGEAAAAALSVRRCKALKEKDLIRTSESDCYCYNQNSQ 60
           MGPRQGRWWLLLWLPPLATLPVRGEAAAAALSVRRCKALKEKDLIRTSESDCYCYNQNSQ
Sbjct: 1   MGPRQGRWWLLLWLPPLATLPVRGEAAAAALSVRRCKALKEKDLIRTSESDCYCYNQNSQ 60

Query: 61  VEWKYIWSTMQVKITSPGLFRIVYIAERHNCQYPENILSFIKCVIHNFWIPKESNEITII 120
           VEWKYIWSTMQVKITSPGLFRIVYIAERHNCQYPENILSFIKCVIHNFWIPKESNEITII
Sbjct: 61  VEWKYIWSTMQVKITSPGLFRIVYIAERHNCQYPENILSFIKCVIHNFWIPKESNEITII 120

Query: 121 INPYRETVCFSVEPVKKIFNYMIHVNRNIMDFKLFLVFVAGVFLFFYARTLSQSPTFYYS 180
           INPYRETVCFSVEPVKKIFNYMIHVNRNIMDFKLFLVFVAGVFLFFYARTLSQSPTFYYS
Sbjct: 121 INPYRETVCFSVEPVKKIFNYMIHVNRNIMDFKLFLVFVAGVFLFFYARTLSQSPTFYYS 180

Query: 181 SGTVLGVLMTLVFVLLLVKRFIPKYSTFWALMVGCWFASVYIVCQLMEDLKWLWYENRIY 240
           SGTVLGVLMTLVFVLLLVKRFIPKYSTFWALMVGCWFASVYIVCQLMEDLKWLWYENRIY
Sbjct: 181 SGTVLGVLMTLVFVLLLVKRFIPKYSTFWALMVGCWFASVYIVCQLMEDLKWLWYENRIY 240

Query: 241 VLGYVLIVGFFSFVVCYKHGPLADDRSRSLLMWMLRLLSLVLVYAGVAVPQFAYAAIILL 300
           VLGYVLIVGFFSFVVCYKHGPLADDRSRSLLMWMLRLLSLVLVYAGVAVPQFAYAAIILL
Sbjct: 241 VLGYVLIVGFFSFVVCYKHGPLADDRSRSLLMWMLRLLSLVLVYAGVAVPQFAYAAIILL 300

Query: 301 MSSWSLHYPLRACSYMRWKMEQWFTSKELVVKYLTEDEYREQADAETNSALEELRRACRK 360
           MSSWSLHYPLRACSYMRWKMEQWFTSKELVVKYLTEDEYREQADAETNSALEELRRACRK
Sbjct: 301 MSSWSLHYPLRACSYMRWKMEQWFTSKELVVKYLTEDEYREQADAETNSALEELRRACRK 360

Query: 361 PDFPSWLVVSRLHTPSKFADFVLGGSHLSPEEISLHEEQYGLGGAFLEEQLFNPSTA 417
           PDFPSWLVVSRLHTPSKFADFVLGGSHLSPEEISLHEEQYGLGGAFLEEQLFNPSTA
Sbjct: 361 PDFPSWLVVSRLHTPSKFADFVLGGSHLSPEEISLHEEQYGLGGAFLEEQLFNPSTA 417


>gi|195972881 transmembrane protein 194A isoform a [Homo sapiens]
          Length = 444

 Score =  262 bits (669), Expect = 5e-70
 Identities = 134/382 (35%), Positives = 224/382 (58%), Gaps = 11/382 (2%)

Query: 39  LKEKDLIRTSESDCYCYNQNSQVEWKYIWSTMQVKITSPGLFRIVYIAERHNCQYPENIL 98
           L+E  +     S  +CY      +W  IW+ +Q+++ S  L R+  +         E + 
Sbjct: 52  LQESQVCEKRASQQFCYTNVLIPKWHDIWTRIQIRVNSSRLVRVTQVENE------EKLK 105

Query: 99  SFIKCVIHNFW---IPKESNEITIIINPYRETVCFSVEPVKKIFNYMIHVNRNIMDFKLF 155
              +  I NF+   + ++ N+  + +  Y    C  VE ++K   Y + V R   D KLF
Sbjct: 106 ELEQFSIWNFFSSFLKEKLNDTYVNVGLYSTKTCLKVEIIEKDTKYSVIVIRRF-DPKLF 164

Query: 156 LVFVAGVFLFFYARTLSQSPTFYYSSGTVLGVLMTLVFVLLLVKRFIPKYSTFWALMVGC 215
           LVF+ G+ LFF    LS+S  FYYS+G  +G++ +L+ ++ ++ +F+PK S  + ++VG 
Sbjct: 165 LVFLLGLMLFFCGDLLSRSQIFYYSTGMTVGIVASLLIIIFILSKFMPKKSPIYVILVGG 224

Query: 216 WFASVYIVCQLMEDLKWLWYENRIYVLGYVLIVGFFSFVVCYKHGPLADDRSRSLLMWML 275
           W  S+Y++  + ++L+ +W     Y+L YVL VGF SF VCYK+GPL ++RS +LL W L
Sbjct: 225 WSFSLYLIQLVFKNLQEIWRCYWQYLLSYVLTVGFMSFAVCYKYGPLENERSINLLTWTL 284

Query: 276 RLLSLVLVYAGVAVPQFAYAAIILLMSSWSLHYPLRACSYMRWKMEQWFTSKELVVKYLT 335
           +L+ L  +Y+G+ +P  A A II+ + + +L +P++   Y+  +       K +  + LT
Sbjct: 285 QLMGLCFMYSGIQIPHIALAIIIIALCTKNLEHPIQ-WLYITCRKVCKGAEKPVPPRLLT 343

Query: 336 EDEYREQADAETNSALEELRRACRKPDFPSWLVVSRLHTPSKFADFVLGGSHLSPEEISL 395
           E+EYR Q + ET  ALEELR  C  PD  +W  VSR+ +P +FADFV G SHL+P E+S+
Sbjct: 344 EEEYRIQGEVETRKALEELREFCNSPDCSAWKTVSRIQSPKRFADFVEGSSHLTPNEVSV 403

Query: 396 HEEQYGLGGAFLEEQLFNPSTA 417
           HE++YGLG    +++++  +++
Sbjct: 404 HEQEYGLGSIIAQDEIYEEASS 425


>gi|195972879 transmembrane protein 194A isoform b [Homo sapiens]
          Length = 371

 Score =  213 bits (542), Expect = 3e-55
 Identities = 98/249 (39%), Positives = 163/249 (65%), Gaps = 1/249 (0%)

Query: 169 RTLSQSPTFYYSSGTVLGVLMTLVFVLLLVKRFIPKYSTFWALMVGCWFASVYIVCQLME 228
           + L QS  FYYS+G  +G++ +L+ ++ ++ +F+PK S  + ++VG W  S+Y++  + +
Sbjct: 105 KELEQSQIFYYSTGMTVGIVASLLIIIFILSKFMPKKSPIYVILVGGWSFSLYLIQLVFK 164

Query: 229 DLKWLWYENRIYVLGYVLIVGFFSFVVCYKHGPLADDRSRSLLMWMLRLLSLVLVYAGVA 288
           +L+ +W     Y+L YVL VGF SF VCYK+GPL ++RS +LL W L+L+ L  +Y+G+ 
Sbjct: 165 NLQEIWRCYWQYLLSYVLTVGFMSFAVCYKYGPLENERSINLLTWTLQLMGLCFMYSGIQ 224

Query: 289 VPQFAYAAIILLMSSWSLHYPLRACSYMRWKMEQWFTSKELVVKYLTEDEYREQADAETN 348
           +P  A A II+ + + +L +P++   Y+  +       K +  + LTE+EYR Q + ET 
Sbjct: 225 IPHIALAIIIIALCTKNLEHPIQ-WLYITCRKVCKGAEKPVPPRLLTEEEYRIQGEVETR 283

Query: 349 SALEELRRACRKPDFPSWLVVSRLHTPSKFADFVLGGSHLSPEEISLHEEQYGLGGAFLE 408
            ALEELR  C  PD  +W  VSR+ +P +FADFV G SHL+P E+S+HE++YGLG    +
Sbjct: 284 KALEELREFCNSPDCSAWKTVSRIQSPKRFADFVEGSSHLTPNEVSVHEQEYGLGSIIAQ 343

Query: 409 EQLFNPSTA 417
           ++++  +++
Sbjct: 344 DEIYEEASS 352


>gi|148612863 transient receptor potential cation channel, subfamily
            M, member 7 [Homo sapiens]
          Length = 1865

 Score = 32.3 bits (72), Expect = 0.82
 Identities = 40/202 (19%), Positives = 72/202 (35%), Gaps = 46/202 (22%)

Query: 166  FYARTLSQSPTFYYSSGTVLGVLMTLVFVLLLVKRFIPKYSTFWALMVGCWFASVYIVCQ 225
            FYA   +    F++++   LG LM   FV+L+    +P         V  W    YI   
Sbjct: 845  FYAFYHAPIVKFWFNTLAYLGFLMLYTFVVLVQMEQLPS--------VQEWIVIAYIFTY 896

Query: 226  LMEDLKWL--------------WYENRIYVLGYVLIVGFF-----------SFVVCYKHG 260
             +E ++ +              W+ +   +   + I+ FF           +F   Y + 
Sbjct: 897  AIEKVREIFMSEAGKVNQKIKVWFSDYFNISDTIAIISFFIGFGLRFGAKWNFANAYDNH 956

Query: 261  PLADDR---SRSLLMWMLRLLSLVLV---------YAGVAVPQFAYAAIILLMSSWSLHY 308
                 R     +++ W +RLL  + V           G  V    Y  +I+ +   S   
Sbjct: 957  VFVAGRLIYCLNIIFWYVRLLDFLAVNQQAGPYVMMIGKMVANMFYIVVIMALVLLSFGV 1016

Query: 309  PLRACSYMRWKMEQWFTSKELV 330
            P +A  Y   +   W  +K++V
Sbjct: 1017 PRKAILYPH-EAPSWTLAKDIV 1037


>gi|26051223 sperm-associated cation channel 2 isoform 2 [Homo
           sapiens]
          Length = 530

 Score = 31.6 bits (70), Expect = 1.4
 Identities = 27/124 (21%), Positives = 54/124 (43%), Gaps = 27/124 (21%)

Query: 151 DFKLFLVFVAGVFLFFYARTLSQSPTFYYSSGTVLGV---LMTLVFVLLLVKRFIPKYST 207
           +F +FLVF+  + L      L  + T  +     L V    + L+F+L ++ +++  +S 
Sbjct: 112 NFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILLKWLSNFSV 171

Query: 208 FW--------------------ALMVGCWFASVYI----VCQLMEDLKWLWYENRIYVLG 243
           FW                     ++VG    SV++    +C+++  LK L    +I ++ 
Sbjct: 172 FWKSAWNVFDFVVTMLSLLPEVVVLVGVTGQSVWLQLLRICRVLRSLKLLAQFRQIQIII 231

Query: 244 YVLI 247
            VL+
Sbjct: 232 LVLV 235


>gi|16876443 sperm-associated cation channel 2 isoform 1 [Homo
           sapiens]
          Length = 528

 Score = 31.6 bits (70), Expect = 1.4
 Identities = 27/124 (21%), Positives = 54/124 (43%), Gaps = 27/124 (21%)

Query: 151 DFKLFLVFVAGVFLFFYARTLSQSPTFYYSSGTVLGV---LMTLVFVLLLVKRFIPKYST 207
           +F +FLVF+  + L      L  + T  +     L V    + L+F+L ++ +++  +S 
Sbjct: 112 NFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILLKWLSNFSV 171

Query: 208 FW--------------------ALMVGCWFASVYI----VCQLMEDLKWLWYENRIYVLG 243
           FW                     ++VG    SV++    +C+++  LK L    +I ++ 
Sbjct: 172 FWKSAWNVFDFVVTMLSLLPEVVVLVGVTGQSVWLQLLRICRVLRSLKLLAQFRQIQIII 231

Query: 244 YVLI 247
            VL+
Sbjct: 232 LVLV 235


>gi|4557803 Niemann-Pick disease, type C1 precursor [Homo sapiens]
          Length = 1278

 Score = 30.8 bits (68), Expect = 2.4
 Identities = 21/80 (26%), Positives = 36/80 (45%), Gaps = 10/80 (12%)

Query: 155  FLVFVAGVFLFFYARTLSQSPTFYYSSGTVLGVLMTLVFVLLLVKRFIPKYSTFWALMVG 214
            + VF   VF  FY + L+      ++ G  LG +  +  VLL  +         W+ ++ 
Sbjct: 1076 YRVFPYSVFYVFYEQYLTIIDDTIFNLGVSLGAIFLVTMVLLGCE--------LWSAVIM 1127

Query: 215  CWFASVYIVCQLMEDLKWLW 234
            C  A++ +V   M  + WLW
Sbjct: 1128 C--ATIAMVLVNMFGVMWLW 1145


>gi|25282391 nurim [Homo sapiens]
          Length = 262

 Score = 30.0 bits (66), Expect = 4.1
 Identities = 23/101 (22%), Positives = 43/101 (42%), Gaps = 2/101 (1%)

Query: 151 DFKLFLVFVAGVFLFFYARTLSQSPTFYYSSGTVLGVLMTLVFVLLLVKRF--IPKYSTF 208
           D  L L+FV    L    R  + +  ++      L V  T + + L+++ +  IPK    
Sbjct: 66  DLGLLLLFVGQHSLMAAERVKAWTSRYFGVLQRSLYVACTALALQLVMRYWEPIPKGPVL 125

Query: 209 WALMVGCWFASVYIVCQLMEDLKWLWYENRIYVLGYVLIVG 249
           W      W   V ++C ++  + WL   + + V  Y  ++G
Sbjct: 126 WEARAEPWATWVPLLCFVLHVISWLLIFSILLVFDYAELMG 166


>gi|26051227 sperm-associated cation channel 2 isoform 4 [Homo
           sapiens]
          Length = 199

 Score = 29.6 bits (65), Expect = 5.3
 Identities = 19/80 (23%), Positives = 37/80 (46%), Gaps = 6/80 (7%)

Query: 151 DFKLFLVFVAGVFLFFYARTLSQSPTFYYSSGTVLGV---LMTLVFVLLLVKRFIPKYST 207
           +F +FLVF+  + L      L  + T  +     L V    + L+F+L ++ +++  +S 
Sbjct: 112 NFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILLKWLSNFSV 171

Query: 208 FWALMVGCWFASVYIVCQLM 227
           FW      W    ++V  L+
Sbjct: 172 FWK---SAWNVFDFVVTMLV 188


>gi|4506813 sodium channel, voltage-gated, type IX, alpha [Homo
            sapiens]
          Length = 1977

 Score = 29.3 bits (64), Expect = 6.9
 Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 3/54 (5%)

Query: 128  VCFSVEPVKKIFN---YMIHVNRNIMDFKLFLVFVAGVFLFFYARTLSQSPTFY 178
            + F+ E V K+ +   Y   V  NI DF + ++ + G+FL     T   SPT +
Sbjct: 1545 ILFTGECVLKLISLRHYYFTVGWNIFDFVVVIISIVGMFLADLIETYFVSPTLF 1598


>gi|4507011 glucose transporter 4 [Homo sapiens]
          Length = 509

 Score = 28.9 bits (63), Expect = 9.0
 Identities = 27/103 (26%), Positives = 46/103 (44%), Gaps = 14/103 (13%)

Query: 164 LFFYARTLSQS-----PTFYYSSGTVLGVLMTLVFVLLLVKRFIPKYSTFWALMVGCWFA 218
           +F+Y+ ++ ++     P +      V+  + TLV VLL V+R   +      L   C  A
Sbjct: 306 VFYYSTSIFETAGVGQPAYATIGAGVVNTVFTLVSVLL-VERAGRRTLHLLGLAGMCGCA 364

Query: 219 SVYIVCQLMEDLKWLWYENRIYVLGYVLIVGFFSFVVCYKHGP 261
            +  V  L+ +        R+  + YV IV  F FV  ++ GP
Sbjct: 365 ILMTVALLLLE--------RVPAMSYVSIVAIFGFVAFFEIGP 399


>gi|9507173 taste receptor T2R5 [Homo sapiens]
          Length = 299

 Score = 28.9 bits (63), Expect = 9.0
 Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 7/72 (9%)

Query: 187 VLMTLVFVLLLVKRFIPKYSTFWALM--VGCWFASVYIV--CQLMEDLK---WLWYENRI 239
           +L   +F L    R++   S FW L+     WFA+   V  C+ +       +LW + R 
Sbjct: 63  ILDLSLFPLFQSSRWLRYLSIFWVLVSQASLWFATFLSVFYCKKITTFDRPAYLWLKQRA 122

Query: 240 YVLGYVLIVGFF 251
           Y L    ++G+F
Sbjct: 123 YNLSLWCLLGYF 134


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.139    0.454 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,943,716
Number of Sequences: 37866
Number of extensions: 658238
Number of successful extensions: 1960
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1950
Number of HSP's gapped (non-prelim): 13
length of query: 417
length of database: 18,247,518
effective HSP length: 105
effective length of query: 312
effective length of database: 14,271,588
effective search space: 4452735456
effective search space used: 4452735456
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.