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Search of human proteins with 217272851
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|217272851 prolyl 4-hydroxylase, alpha I subunit isoform 3
precursor [Homo sapiens]
(516 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|217272851 prolyl 4-hydroxylase, alpha I subunit isoform 3 pre... 1050 0.0
gi|63252886 prolyl 4-hydroxylase, alpha I subunit isoform 1 prec... 1039 0.0
gi|217272849 prolyl 4-hydroxylase, alpha I subunit isoform 2 pre... 1019 0.0
gi|63252888 prolyl 4-hydroxylase, alpha I subunit isoform 2 prec... 1019 0.0
gi|217272863 prolyl 4-hydroxylase, alpha II subunit isoform 1 pr... 663 0.0
gi|4758868 prolyl 4-hydroxylase, alpha II subunit isoform 1 prec... 663 0.0
gi|217272861 prolyl 4-hydroxylase, alpha II subunit isoform 2 pr... 643 0.0
gi|63252893 prolyl 4-hydroxylase, alpha II subunit isoform 2 pre... 643 0.0
gi|63252891 prolyl 4-hydroxylase, alpha II subunit isoform 2 pre... 643 0.0
gi|33589818 prolyl 4-hydroxylase, alpha III subunit precursor [H... 285 9e-77
gi|29570771 hypoxia-inducible factor prolyl 4-hydroxylase isofor... 59 8e-09
gi|64085083 hypoxia-inducible factor prolyl 4-hydroxylase isofor... 57 3e-08
gi|216548091 leucine zipper protein 1 [Homo sapiens] 39 0.015
gi|216548085 leucine zipper protein 1 [Homo sapiens] 39 0.015
gi|197313662 leprecan-like 1 isoform b [Homo sapiens] 34 0.37
gi|27764882 leprecan-like 1 isoform a [Homo sapiens] 34 0.37
gi|64276486 serologically defined colon cancer antigen 10 [Homo ... 33 0.48
gi|4826870 nucleobindin 2 [Homo sapiens] 32 1.1
gi|238859557 regulatory factor X1 [Homo sapiens] 32 1.4
gi|10337581 type I hair keratin 3B [Homo sapiens] 31 3.1
gi|186928835 leprecan 1 isoform 1 [Homo sapiens] 31 3.1
gi|226371643 leprecan 1 isoform 2 [Homo sapiens] 31 3.1
gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens] 31 3.1
gi|221316624 dystonin isoform 4 [Homo sapiens] 30 4.1
gi|221316622 dystonin isoform 3 [Homo sapiens] 30 4.1
gi|221316618 dystonin isoform 2 [Homo sapiens] 30 4.1
gi|34577047 dystonin isoform 1 [Homo sapiens] 30 4.1
gi|34577049 dystonin isoform 1eA precursor [Homo sapiens] 30 4.1
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 30 4.1
gi|157739936 chromosome 10 open reading frame 68 [Homo sapiens] 30 4.1
>gi|217272851 prolyl 4-hydroxylase, alpha I subunit isoform 3
precursor [Homo sapiens]
Length = 516
Score = 1050 bits (2715), Expect = 0.0
Identities = 516/516 (100%), Positives = 516/516 (100%)
Query: 1 MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA 60
MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA
Sbjct: 1 MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA 60
Query: 61 EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY 120
EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY
Sbjct: 61 EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY 120
Query: 121 FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY 180
FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY
Sbjct: 121 FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY 180
Query: 181 YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR 240
YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR
Sbjct: 181 YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR 240
Query: 241 ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGVAVDYLPERQKYEMLCRGEGIKM 300
ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGVAVDYLPERQKYEMLCRGEGIKM
Sbjct: 241 ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGVAVDYLPERQKYEMLCRGEGIKM 300
Query: 301 TPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRL 360
TPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRL
Sbjct: 301 TPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRL 360
Query: 361 SRATVHDPETGKLTTAQYRVSKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQKDEP 420
SRATVHDPETGKLTTAQYRVSKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQKDEP
Sbjct: 361 SRATVHDPETGKLTTAQYRVSKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQKDEP 420
Query: 421 DAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYST 480
DAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYST
Sbjct: 421 DAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYST 480
Query: 481 RHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE 516
RHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE
Sbjct: 481 RHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE 516
>gi|63252886 prolyl 4-hydroxylase, alpha I subunit isoform 1
precursor [Homo sapiens]
Length = 534
Score = 1039 bits (2686), Expect = 0.0
Identities = 516/534 (96%), Positives = 516/534 (96%), Gaps = 18/534 (3%)
Query: 1 MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA 60
MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA
Sbjct: 1 MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA 60
Query: 61 EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY 120
EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY
Sbjct: 61 EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY 120
Query: 121 FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY 180
FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY
Sbjct: 121 FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY 180
Query: 181 YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR 240
YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR
Sbjct: 181 YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR 240
Query: 241 ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGVAVDYLPERQKYEMLCRGEGIKM 300
ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGVAVDYLPERQKYEMLCRGEGIKM
Sbjct: 241 ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGVAVDYLPERQKYEMLCRGEGIKM 300
Query: 301 TPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRL 360
TPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRL
Sbjct: 301 TPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRL 360
Query: 361 SRATVHDPETGKLTTAQYRVSKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQ---- 416
SRATVHDPETGKLTTAQYRVSKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQ
Sbjct: 361 SRATVHDPETGKLTTAQYRVSKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQVANY 420
Query: 417 --------------KDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKG 462
KDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKG
Sbjct: 421 GVGGQYEPHFDFARKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKG 480
Query: 463 TAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE 516
TAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE
Sbjct: 481 TAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE 534
>gi|217272849 prolyl 4-hydroxylase, alpha I subunit isoform 2
precursor [Homo sapiens]
Length = 534
Score = 1019 bits (2636), Expect = 0.0
Identities = 506/534 (94%), Positives = 509/534 (95%), Gaps = 18/534 (3%)
Query: 1 MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA 60
MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA
Sbjct: 1 MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA 60
Query: 61 EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY 120
EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY
Sbjct: 61 EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY 120
Query: 121 FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY 180
FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY
Sbjct: 121 FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY 180
Query: 181 YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR 240
YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR
Sbjct: 181 YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR 240
Query: 241 ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGVAVDYLPERQKYEMLCRGEGIKM 300
ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGVAVDYLPERQKYEMLCRGEGIKM
Sbjct: 241 ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGVAVDYLPERQKYEMLCRGEGIKM 300
Query: 301 TPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRL 360
TPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRL
Sbjct: 301 TPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRL 360
Query: 361 SRATVHDPETGKLTTAQYRVSKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQ---- 416
RAT+ +P TG L T YR+SKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQ
Sbjct: 361 RRATISNPITGDLETVHYRISKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQVANY 420
Query: 417 --------------KDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKG 462
KDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKG
Sbjct: 421 GVGGQYEPHFDFARKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKG 480
Query: 463 TAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE 516
TAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE
Sbjct: 481 TAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE 534
>gi|63252888 prolyl 4-hydroxylase, alpha I subunit isoform 2
precursor [Homo sapiens]
Length = 534
Score = 1019 bits (2636), Expect = 0.0
Identities = 506/534 (94%), Positives = 509/534 (95%), Gaps = 18/534 (3%)
Query: 1 MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA 60
MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA
Sbjct: 1 MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA 60
Query: 61 EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY 120
EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY
Sbjct: 61 EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY 120
Query: 121 FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY 180
FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY
Sbjct: 121 FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY 180
Query: 181 YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR 240
YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR
Sbjct: 181 YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR 240
Query: 241 ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGVAVDYLPERQKYEMLCRGEGIKM 300
ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGVAVDYLPERQKYEMLCRGEGIKM
Sbjct: 241 ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGVAVDYLPERQKYEMLCRGEGIKM 300
Query: 301 TPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRL 360
TPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRL
Sbjct: 301 TPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAKPRL 360
Query: 361 SRATVHDPETGKLTTAQYRVSKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQ---- 416
RAT+ +P TG L T YR+SKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQ
Sbjct: 361 RRATISNPITGDLETVHYRISKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQVANY 420
Query: 417 --------------KDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKG 462
KDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKG
Sbjct: 421 GVGGQYEPHFDFARKDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKKG 480
Query: 463 TAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE 516
TAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE
Sbjct: 481 TAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE 534
>gi|217272863 prolyl 4-hydroxylase, alpha II subunit isoform 1
precursor [Homo sapiens]
Length = 535
Score = 663 bits (1710), Expect = 0.0
Identities = 322/537 (59%), Positives = 407/537 (75%), Gaps = 32/537 (5%)
Query: 1 MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA 60
M W+ G+L S FFTSIG MTDLI+ EK+LV SLK+YI EE KL +IK WA
Sbjct: 10 MAWF----GVL---SCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWA 62
Query: 61 EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY 120
K++ LTS + D EG++ HPVNA+KL+KRLNT+W LE+LVL+D + GFI+NL++QRQ+
Sbjct: 63 NKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQRQF 122
Query: 121 FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY 180
FP DED++GAAKAL+RLQDTY LD TIS+G LPG K+++ L+ +DCF +G+ AY E DY
Sbjct: 123 FPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDY 182
Query: 181 YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR 240
YHT LWMEQ L+QLD GE +T K VLDYLSYAV+Q GDL +AL LT++LL LDP H+R
Sbjct: 183 YHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHER 242
Query: 241 ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGV---AVDYLPERQKYEMLCRGEG 297
A GNL+YFE ++ +E++ K+ ++ + TP +G+ VDYLPER YE LCRGEG
Sbjct: 243 AGGNLRYFEQLLEEERE--KTLTNQTEAELATP--EGIYERPVDYLPERDVYESLCRGEG 298
Query: 298 IKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAK 357
+K+TPRRQK+LFCRYH GNR P+ ++AP K+EDEWD P I+R++D++SD EIE +K++AK
Sbjct: 299 VKLTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAK 358
Query: 358 PRLSRATVHDPETGKLTTAQYRVSKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQ- 416
P+L+RATV DP+TG LT A YRVSKS+WL ++PVV+R+N R+Q +TGL V TAE LQ
Sbjct: 359 PKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQV 418
Query: 417 -----------------KDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWP 459
DE D FK LGTGNR+AT+L YMSDV AGGATVFP++GA++WP
Sbjct: 419 ANYGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWP 478
Query: 460 KKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE 516
KKGTAVFWYNL SGEGDY TRHAACPVLVG KWVSNKW HERGQEF RPC +E++
Sbjct: 479 KKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 535
>gi|4758868 prolyl 4-hydroxylase, alpha II subunit isoform 1
precursor [Homo sapiens]
Length = 535
Score = 663 bits (1710), Expect = 0.0
Identities = 322/537 (59%), Positives = 407/537 (75%), Gaps = 32/537 (5%)
Query: 1 MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA 60
M W+ G+L S FFTSIG MTDLI+ EK+LV SLK+YI EE KL +IK WA
Sbjct: 10 MAWF----GVL---SCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWA 62
Query: 61 EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY 120
K++ LTS + D EG++ HPVNA+KL+KRLNT+W LE+LVL+D + GFI+NL++QRQ+
Sbjct: 63 NKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQRQF 122
Query: 121 FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY 180
FP DED++GAAKAL+RLQDTY LD TIS+G LPG K+++ L+ +DCF +G+ AY E DY
Sbjct: 123 FPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDY 182
Query: 181 YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR 240
YHT LWMEQ L+QLD GE +T K VLDYLSYAV+Q GDL +AL LT++LL LDP H+R
Sbjct: 183 YHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHER 242
Query: 241 ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGV---AVDYLPERQKYEMLCRGEG 297
A GNL+YFE ++ +E++ K+ ++ + TP +G+ VDYLPER YE LCRGEG
Sbjct: 243 AGGNLRYFEQLLEEERE--KTLTNQTEAELATP--EGIYERPVDYLPERDVYESLCRGEG 298
Query: 298 IKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAK 357
+K+TPRRQK+LFCRYH GNR P+ ++AP K+EDEWD P I+R++D++SD EIE +K++AK
Sbjct: 299 VKLTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAK 358
Query: 358 PRLSRATVHDPETGKLTTAQYRVSKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQ- 416
P+L+RATV DP+TG LT A YRVSKS+WL ++PVV+R+N R+Q +TGL V TAE LQ
Sbjct: 359 PKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQV 418
Query: 417 -----------------KDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWP 459
DE D FK LGTGNR+AT+L YMSDV AGGATVFP++GA++WP
Sbjct: 419 ANYGVGGQYEPHFDFSRNDERDTFKHLGTGNRVATFLNYMSDVEAGGATVFPDLGAAIWP 478
Query: 460 KKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE 516
KKGTAVFWYNL SGEGDY TRHAACPVLVG KWVSNKW HERGQEF RPC +E++
Sbjct: 479 KKGTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 535
>gi|217272861 prolyl 4-hydroxylase, alpha II subunit isoform 2
precursor [Homo sapiens]
Length = 533
Score = 643 bits (1658), Expect = 0.0
Identities = 315/535 (58%), Positives = 400/535 (74%), Gaps = 30/535 (5%)
Query: 1 MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA 60
M W+ G+L S FFTSIG MTDLI+ EK+LV SLK+YI EE KL +IK WA
Sbjct: 10 MAWF----GVL---SCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWA 62
Query: 61 EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY 120
K++ LTS + D EG++ HPVNA+KL+KRLNT+W LE+LVL+D + GFI+NL++QRQ+
Sbjct: 63 NKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQRQF 122
Query: 121 FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY 180
FP DED++GAAKAL+RLQDTY LD TIS+G LPG K+++ L+ +DCF +G+ AY E DY
Sbjct: 123 FPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDY 182
Query: 181 YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR 240
YHT LWMEQ L+QLD GE +T K VLDYLSYAV+Q GDL +AL LT++LL LDP H+R
Sbjct: 183 YHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHER 242
Query: 241 ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGV---AVDYLPERQKYEMLCRGEG 297
A GNL+YFE ++ +E++ K+ ++ + TP +G+ VDYLPER YE LCRGEG
Sbjct: 243 AGGNLRYFEQLLEEERE--KTLTNQTEAELATP--EGIYERPVDYLPERDVYESLCRGEG 298
Query: 298 IKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAK 357
+K+TPRRQK+LFCRYH GNR P+ ++AP K+EDEWD P I+R++D++SD EIE +K++AK
Sbjct: 299 VKLTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAK 358
Query: 358 PRLSRATVHDPETGKLTTAQYRVSKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQ- 416
P+L+RATV DP+TG LT A YRVSKS+WL ++PVV+R+N R+Q +TGL V TAE LQ
Sbjct: 359 PKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQV 418
Query: 417 ---------------KDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKK 461
P GNR+AT+L YMSDV AGGATVFP++GA++WPKK
Sbjct: 419 ANYGVGGQYEPHFDFSRRPFDSGLKTEGNRLATFLNYMSDVEAGGATVFPDLGAAIWPKK 478
Query: 462 GTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE 516
GTAVFWYNL SGEGDY TRHAACPVLVG KWVSNKW HERGQEF RPC +E++
Sbjct: 479 GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 533
>gi|63252893 prolyl 4-hydroxylase, alpha II subunit isoform 2
precursor [Homo sapiens]
Length = 533
Score = 643 bits (1658), Expect = 0.0
Identities = 315/535 (58%), Positives = 400/535 (74%), Gaps = 30/535 (5%)
Query: 1 MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA 60
M W+ G+L S FFTSIG MTDLI+ EK+LV SLK+YI EE KL +IK WA
Sbjct: 10 MAWF----GVL---SCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWA 62
Query: 61 EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY 120
K++ LTS + D EG++ HPVNA+KL+KRLNT+W LE+LVL+D + GFI+NL++QRQ+
Sbjct: 63 NKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQRQF 122
Query: 121 FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY 180
FP DED++GAAKAL+RLQDTY LD TIS+G LPG K+++ L+ +DCF +G+ AY E DY
Sbjct: 123 FPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDY 182
Query: 181 YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR 240
YHT LWMEQ L+QLD GE +T K VLDYLSYAV+Q GDL +AL LT++LL LDP H+R
Sbjct: 183 YHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHER 242
Query: 241 ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGV---AVDYLPERQKYEMLCRGEG 297
A GNL+YFE ++ +E++ K+ ++ + TP +G+ VDYLPER YE LCRGEG
Sbjct: 243 AGGNLRYFEQLLEEERE--KTLTNQTEAELATP--EGIYERPVDYLPERDVYESLCRGEG 298
Query: 298 IKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAK 357
+K+TPRRQK+LFCRYH GNR P+ ++AP K+EDEWD P I+R++D++SD EIE +K++AK
Sbjct: 299 VKLTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAK 358
Query: 358 PRLSRATVHDPETGKLTTAQYRVSKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQ- 416
P+L+RATV DP+TG LT A YRVSKS+WL ++PVV+R+N R+Q +TGL V TAE LQ
Sbjct: 359 PKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQV 418
Query: 417 ---------------KDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKK 461
P GNR+AT+L YMSDV AGGATVFP++GA++WPKK
Sbjct: 419 ANYGVGGQYEPHFDFSRRPFDSGLKTEGNRLATFLNYMSDVEAGGATVFPDLGAAIWPKK 478
Query: 462 GTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE 516
GTAVFWYNL SGEGDY TRHAACPVLVG KWVSNKW HERGQEF RPC +E++
Sbjct: 479 GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 533
>gi|63252891 prolyl 4-hydroxylase, alpha II subunit isoform 2
precursor [Homo sapiens]
Length = 533
Score = 643 bits (1658), Expect = 0.0
Identities = 315/535 (58%), Positives = 400/535 (74%), Gaps = 30/535 (5%)
Query: 1 MIWYILIIGILLPQSLAHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWA 60
M W+ G+L S FFTSIG MTDLI+ EK+LV SLK+YI EE KL +IK WA
Sbjct: 10 MAWF----GVL---SCVQAEFFTSIGHMTDLIYAEKELVQSLKEYILVEEAKLSKIKSWA 62
Query: 61 EKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLVLKDMSDGFISNLTIQRQY 120
K++ LTS + D EG++ HPVNA+KL+KRLNT+W LE+LVL+D + GFI+NL++QRQ+
Sbjct: 63 NKMEALTSKSAADAEGYLAHPVNAYKLVKRLNTDWPALEDLVLQDSAAGFIANLSVQRQF 122
Query: 121 FPNDEDQVGAAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADY 180
FP DED++GAAKAL+RLQDTY LD TIS+G LPG K+++ L+ +DCF +G+ AY E DY
Sbjct: 123 FPTDEDEIGAAKALMRLQDTYRLDPGTISRGELPGTKYQAMLSVDDCFGMGRSAYNEGDY 182
Query: 181 YHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQR 240
YHT LWMEQ L+QLD GE +T K VLDYLSYAV+Q GDL +AL LT++LL LDP H+R
Sbjct: 183 YHTVLWMEQVLKQLDAGEEATTTKSQVLDYLSYAVFQLGDLHRALELTRRLLSLDPSHER 242
Query: 241 ANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGV---AVDYLPERQKYEMLCRGEG 297
A GNL+YFE ++ +E++ K+ ++ + TP +G+ VDYLPER YE LCRGEG
Sbjct: 243 AGGNLRYFEQLLEEERE--KTLTNQTEAELATP--EGIYERPVDYLPERDVYESLCRGEG 298
Query: 298 IKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHDIISDAEIEIVKDLAK 357
+K+TPRRQK+LFCRYH GNR P+ ++AP K+EDEWD P I+R++D++SD EIE +K++AK
Sbjct: 299 VKLTPRRQKRLFCRYHHGNRAPQLLIAPFKEEDEWDSPHIVRYYDVMSDEEIERIKEIAK 358
Query: 358 PRLSRATVHDPETGKLTTAQYRVSKSAWLSGYENPVVSRINMRIQDLTGLDVSTAEELQ- 416
P+L+RATV DP+TG LT A YRVSKS+WL ++PVV+R+N R+Q +TGL V TAE LQ
Sbjct: 359 PKLARATVRDPKTGVLTVASYRVSKSSWLEEDDDPVVARVNRRMQHITGLTVKTAELLQV 418
Query: 417 ---------------KDEPDAFKELGTGNRIATWLFYMSDVSAGGATVFPEVGASVWPKK 461
P GNR+AT+L YMSDV AGGATVFP++GA++WPKK
Sbjct: 419 ANYGVGGQYEPHFDFSRRPFDSGLKTEGNRLATFLNYMSDVEAGGATVFPDLGAAIWPKK 478
Query: 462 GTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERGQEFRRPCTLSELE 516
GTAVFWYNL SGEGDY TRHAACPVLVG KWVSNKW HERGQEF RPC +E++
Sbjct: 479 GTAVFWYNLLRSGEGDYRTRHAACPVLVGCKWVSNKWFHERGQEFLRPCGSTEVD 533
>gi|33589818 prolyl 4-hydroxylase, alpha III subunit precursor [Homo
sapiens]
Length = 544
Score = 285 bits (728), Expect = 9e-77
Identities = 188/550 (34%), Positives = 293/550 (53%), Gaps = 62/550 (11%)
Query: 5 ILIIGILLPQSLAHPG-FFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWAEKL 63
+L +G P+ A G F+++ + + E+ L+ L+ Y++ EE +L + ++ +K+
Sbjct: 13 VLALGTGDPERAAARGDTFSALTSVARALAPERRLLGLLRRYLRGEEARLRDLTRFYDKV 72
Query: 64 DRLTSTATKDPEGFVGHPVNAFKLMKRLNTEWSELENLV-----LKDMSDGFISNLTIQR 118
L +T V +P+ AF L+KRL ++W + + + ++ + DG+
Sbjct: 73 LSLHEDSTTP----VANPLLAFTLIKRLQSDWRNVVHSLEASENIRALKDGYEK----VE 124
Query: 119 QYFPNDEDQVGAAKALLRLQDTYNLDTDTISKG-----------NLPGVKHKSFLTAEDC 167
Q P ED GAA+AL+RLQD Y L+ +++G +L K LT +DC
Sbjct: 125 QDLPAFEDLEGAARALMRLQDVYMLNVKGLARGVFQRVTGSAITDLYSPKRLFSLTGDDC 184
Query: 168 FELGKVAYTEADYYHTELWMEQALRQL--DEGEISTIDKVSV---LDYLSYAVYQQGDLD 222
F++GKVAY DYYH W+E+A+ GE T D+ S+ LD+L++A ++ G++
Sbjct: 185 FQVGKVAYDMGDYYHAIPWLEEAVSLFRGSYGEWKTEDEASLEDALDHLAFAYFRAGNVS 244
Query: 223 KALLLTKKLLELDPEHQRANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKKGVAVDY 282
AL L+++ L P+++R N+ +E ++A+ N ++ + P +
Sbjct: 245 CALSLSREFLLYSPDNKRMARNVLKYERLLAESP--NHVVAEAVIQRPNIP--------H 294
Query: 283 LPERQKYEMLCRGEGIKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPRIIRFHD 342
L R YE LC+ G + T + L+C Y + N N +L P ++E +P I +HD
Sbjct: 295 LQTRDTYEGLCQTLGSQPTLYQIPSLYCSY-ETNSNAYLLLQPIRKEVIHLEPYIALYHD 353
Query: 343 IISDAEIEIVKDLAKPRLSRATVHDPETGKLTTAQYRVSKSAWLSGYENPVVSRINMRIQ 402
+SD+E + +++LA+P L R+ V E K +YR+SKSAWL +P + +N RI
Sbjct: 354 FVSDSEAQKIRELAEPWLQRSVVASGE--KQLQVEYRISKSAWLKDTVDPKLVTLNHRIA 411
Query: 403 DLTGLDVST--AEELQ-----------------KDEPDAFKELGTGNRIATWLFYMSDVS 443
LTGLDV AE LQ + +GNR+AT++ Y+S V
Sbjct: 412 ALTGLDVRPPYAEYLQVVNYGIGGHYEPHFDHATSPSSPLYRMKSGNRVATFMIYLSSVE 471
Query: 444 AGGATVFPEVGASVWPKKGTAVFWYNLFASGEGDYSTRHAACPVLVGNKWVSNKWLHERG 503
AGGAT F SV + A+FW+NL SGEGD T HA CPVLVG+KWV+NKW+HE G
Sbjct: 472 AGGATAFIYANLSVPVVRNAALFWWNLHRSGEGDSDTLHAGCPVLVGDKWVANKWIHEYG 531
Query: 504 QEFRRPCTLS 513
QEFRRPC+ S
Sbjct: 532 QEFRRPCSSS 541
>gi|29570771 hypoxia-inducible factor prolyl 4-hydroxylase isoform a
[Homo sapiens]
Length = 502
Score = 59.3 bits (142), Expect = 8e-09
Identities = 36/106 (33%), Positives = 47/106 (44%), Gaps = 34/106 (32%)
Query: 428 TGNRIATWLFYMSDVSAGGATVFPEV---------------------------GASVWPK 460
T R T LFY+++V+ GG TVFP V P+
Sbjct: 355 TSCRYMTVLFYLNNVTGGGETVFPVADNRTYDEMSLIQDDVDLRDTRRHCDKGNLRVKPQ 414
Query: 461 KGTAVFWYNLFASGEG------DYSTRHAACPVLVGNKWVSNKWLH 500
+GTAVFWYN G+G DYS H C V G KW++N W++
Sbjct: 415 QGTAVFWYNYLPDGQGWVGDVDDYSL-HGGCLVTRGTKWIANNWIN 459
>gi|64085083 hypoxia-inducible factor prolyl 4-hydroxylase isoform c
[Homo sapiens]
Length = 563
Score = 57.4 bits (137), Expect = 3e-08
Identities = 34/100 (34%), Positives = 45/100 (45%), Gaps = 34/100 (34%)
Query: 434 TWLFYMSDVSAGGATVFPEV---------------------------GASVWPKKGTAVF 466
T LFY+++V+ GG TVFP V P++GTAVF
Sbjct: 422 TVLFYLNNVTGGGETVFPVADNRTYDEMSLIQDDVDLRDTRRHCDKGNLRVKPQQGTAVF 481
Query: 467 WYNLFASGEG------DYSTRHAACPVLVGNKWVSNKWLH 500
WYN G+G DYS H C V G KW++N W++
Sbjct: 482 WYNYLPDGQGWVGDVDDYSL-HGGCLVTRGTKWIANNWIN 520
>gi|216548091 leucine zipper protein 1 [Homo sapiens]
Length = 1076
Score = 38.5 bits (88), Expect = 0.015
Identities = 64/291 (21%), Positives = 124/291 (42%), Gaps = 33/291 (11%)
Query: 32 IHTEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRL 91
I +DL +K+ ++ EE+ ++K E+L + + K E F + +L L
Sbjct: 82 IKRAEDLCRLMKEKLEEEENLTRELKSEIERLQKRMAELEKLEEAFSRSKNDCTQLCLSL 141
Query: 92 NTEWSELENLVLKDMSDGFISNLTIQRQYFPNDEDQVGAAKALL--RLQDTYNLDTDTIS 149
N E NL K S+ + L ++ + + ED++ + L L+ +L +S
Sbjct: 142 NEE----RNLTKKISSE--LEMLRVKVKELESSEDRLDKTEQSLASELEKLKSLTLSFVS 195
Query: 150 KGNLPGVKHK--SFLTAEDCFELGKVAYTEADYYHTELWMEQALRQLDEGEISTID---- 203
+ K K L E +L + DY +E+ ++++G ST+
Sbjct: 196 ERKYLNEKEKENEKLIKELTQKLEQNKKMNRDYTRNASNLERNDLRIEDGISSTLPSKES 255
Query: 204 -KVSVLDYLSYAVYQQGDLDK----ALLLTKKLLELDPEHQRANGNLKYFEYIMAKEKDV 258
+ LDYL + + + K+ +L+ E ++ +K+FE + + K +
Sbjct: 256 RRKGGLDYLKQVENETRNKSENEKNRNQEDNKVKDLNQEIEKLKTQIKHFESLEEELKKM 315
Query: 259 NKSASDDQSDQKTTPKKKGVAVDYLPERQKYEMLC-RGEGIKMTPRRQKKL 308
KS ++D D +YL E+ K ++L + E IK+ ++QK+L
Sbjct: 316 -KSKNNDLQD------------NYLSEQNKNKLLASQLEEIKLQIKKQKEL 353
>gi|216548085 leucine zipper protein 1 [Homo sapiens]
Length = 1076
Score = 38.5 bits (88), Expect = 0.015
Identities = 64/291 (21%), Positives = 124/291 (42%), Gaps = 33/291 (11%)
Query: 32 IHTEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRL 91
I +DL +K+ ++ EE+ ++K E+L + + K E F + +L L
Sbjct: 82 IKRAEDLCRLMKEKLEEEENLTRELKSEIERLQKRMAELEKLEEAFSRSKNDCTQLCLSL 141
Query: 92 NTEWSELENLVLKDMSDGFISNLTIQRQYFPNDEDQVGAAKALL--RLQDTYNLDTDTIS 149
N E NL K S+ + L ++ + + ED++ + L L+ +L +S
Sbjct: 142 NEE----RNLTKKISSE--LEMLRVKVKELESSEDRLDKTEQSLASELEKLKSLTLSFVS 195
Query: 150 KGNLPGVKHK--SFLTAEDCFELGKVAYTEADYYHTELWMEQALRQLDEGEISTID---- 203
+ K K L E +L + DY +E+ ++++G ST+
Sbjct: 196 ERKYLNEKEKENEKLIKELTQKLEQNKKMNRDYTRNASNLERNDLRIEDGISSTLPSKES 255
Query: 204 -KVSVLDYLSYAVYQQGDLDK----ALLLTKKLLELDPEHQRANGNLKYFEYIMAKEKDV 258
+ LDYL + + + K+ +L+ E ++ +K+FE + + K +
Sbjct: 256 RRKGGLDYLKQVENETRNKSENEKNRNQEDNKVKDLNQEIEKLKTQIKHFESLEEELKKM 315
Query: 259 NKSASDDQSDQKTTPKKKGVAVDYLPERQKYEMLC-RGEGIKMTPRRQKKL 308
KS ++D D +YL E+ K ++L + E IK+ ++QK+L
Sbjct: 316 -KSKNNDLQD------------NYLSEQNKNKLLASQLEEIKLQIKKQKEL 353
>gi|197313662 leprecan-like 1 isoform b [Homo sapiens]
Length = 527
Score = 33.9 bits (76), Expect = 0.37
Identities = 25/80 (31%), Positives = 41/80 (51%), Gaps = 5/80 (6%)
Query: 178 ADYYHTELWME-QALRQLDE--GEISTIDKVSVL--DYLSYAVYQQGDLDKALLLTKKLL 232
AD+Y L + + +R+L G +S I+ L DYL +A Y+ G+ KAL K L
Sbjct: 93 ADHYMQVLVCQHECVRELATRPGRLSPIENFLPLHYDYLQFAYYRVGEYVKALECAKAYL 152
Query: 233 ELDPEHQRANGNLKYFEYIM 252
P+ + N+ Y+E ++
Sbjct: 153 LCHPDDEDVLDNVDYYESLL 172
>gi|27764882 leprecan-like 1 isoform a [Homo sapiens]
Length = 708
Score = 33.9 bits (76), Expect = 0.37
Identities = 25/80 (31%), Positives = 41/80 (51%), Gaps = 5/80 (6%)
Query: 178 ADYYHTELWME-QALRQLDE--GEISTIDKVSVL--DYLSYAVYQQGDLDKALLLTKKLL 232
AD+Y L + + +R+L G +S I+ L DYL +A Y+ G+ KAL K L
Sbjct: 274 ADHYMQVLVCQHECVRELATRPGRLSPIENFLPLHYDYLQFAYYRVGEYVKALECAKAYL 333
Query: 233 ELDPEHQRANGNLKYFEYIM 252
P+ + N+ Y+E ++
Sbjct: 334 LCHPDDEDVLDNVDYYESLL 353
>gi|64276486 serologically defined colon cancer antigen 10 [Homo
sapiens]
Length = 472
Score = 33.5 bits (75), Expect = 0.48
Identities = 26/82 (31%), Positives = 43/82 (52%), Gaps = 4/82 (4%)
Query: 229 KKLLELDPEHQRANGNLKYFEYIMAKEKDVNKSA--SDDQSDQKTTPKKKGVAVDYLPER 286
KK + E ++ LK E + AK+K V +A ++ +S+++ P VA +Y E+
Sbjct: 307 KKSVSRSEELRKEARQLKR-ELLAAKQKKVENAAKQAEKRSEEEEAPPDGAVA-EYRREK 364
Query: 287 QKYEMLCRGEGIKMTPRRQKKL 308
QKYE L + + K T R + L
Sbjct: 365 QKYEALRKQQSKKGTSREDQTL 386
>gi|4826870 nucleobindin 2 [Homo sapiens]
Length = 420
Score = 32.3 bits (72), Expect = 1.1
Identities = 57/249 (22%), Positives = 100/249 (40%), Gaps = 61/249 (24%)
Query: 33 HTEKDLVTSL-KDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRL 91
H ++ + +L ++ K EE K E++KK E ++ +KD +L
Sbjct: 186 HERREYLKTLNEEKRKEEESKFEEMKKKHENHPKVNHPGSKD----------------QL 229
Query: 92 NTEWSELENLVLKDM------------SDGFIS--------NLTIQRQYFPNDE--DQVG 129
W E + L D SDGF+ +++ Y P +E D V
Sbjct: 230 KEVWEETDGLDPNDFDPKTFFKLHDVNSDGFLDEQELEALFTKELEKVYDPKNEEDDMVE 289
Query: 130 AAKALLRLQDTYNLDTDTISKGNLPGVKHKSFLTAEDCFELGKVAYTEADYYHTELWMEQ 189
+ LR+++ + DT +K L V + FL A + K + E D + T
Sbjct: 290 MEEERLRMREHVMNEVDT-NKDRL--VTLEEFLKATE-----KKEFLEPDSWET------ 335
Query: 190 ALRQLDEGEISTIDKVSVLDYLSYAVYQQGDL-DKALLLTKKLLELDPEHQRANG-NLKY 247
LD+ + T +++ +Y + Q+ +L KA L K+ EL +H + L+Y
Sbjct: 336 ----LDQQQFFTEEELK--EYENIIALQENELKKKADELQKQKEELQRQHDQLEAQKLEY 389
Query: 248 FEYIMAKEK 256
+ I E+
Sbjct: 390 HQVIQQMEQ 398
>gi|238859557 regulatory factor X1 [Homo sapiens]
Length = 979
Score = 32.0 bits (71), Expect = 1.4
Identities = 19/73 (26%), Positives = 34/73 (46%), Gaps = 4/73 (5%)
Query: 35 EKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRLNTE 94
E +V L+ K + +++WA LD + S K +G G P K K +
Sbjct: 797 EDRVVQRLEQDFKVTLQQQNSLEQWAAWLDGVVSQVLKPYQGSAGFP----KAAKLFLLK 852
Query: 95 WSELENLVLKDMS 107
WS ++V++D++
Sbjct: 853 WSFYSSMVIRDLT 865
>gi|10337581 type I hair keratin 3B [Homo sapiens]
Length = 404
Score = 30.8 bits (68), Expect = 3.1
Identities = 22/70 (31%), Positives = 40/70 (57%), Gaps = 6/70 (8%)
Query: 178 ADYYHTELWMEQALRQLDEGEISTIDKVSVLDYLSYAVYQQGDLDKAL-LLTKKLLELDP 236
AD + T+ EQ+LRQL E +I+++ + +LD L+ + DL+ + L ++LL L
Sbjct: 138 ADDFRTKYQTEQSLRQLVESDINSLRR--ILDELTLC---RSDLEAQMESLKEELLSLKQ 192
Query: 237 EHQRANGNLK 246
H++ L+
Sbjct: 193 NHEQEVNTLR 202
>gi|186928835 leprecan 1 isoform 1 [Homo sapiens]
Length = 736
Score = 30.8 bits (68), Expect = 3.1
Identities = 23/107 (21%), Positives = 40/107 (37%), Gaps = 15/107 (14%)
Query: 204 KVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLKYFEYIM-AKEKDVNKSA 262
K S +YL A ++ L+KA+ +PEH NL Y++ + KE D
Sbjct: 142 KRSPYNYLQVAYFKINKLEKAVAAAHTFFVGNPEHMEMQQNLDYYQTMSGVKEADFKDLE 201
Query: 263 S--------------DDQSDQKTTPKKKGVAVDYLPERQKYEMLCRG 295
+ ++ Q+ P + +Y ++ LC G
Sbjct: 202 TQPHMQEFRLGVRLYSEEQPQEAVPHLEAALQEYFVAYEECRALCEG 248
>gi|226371643 leprecan 1 isoform 2 [Homo sapiens]
Length = 697
Score = 30.8 bits (68), Expect = 3.1
Identities = 23/107 (21%), Positives = 40/107 (37%), Gaps = 15/107 (14%)
Query: 204 KVSVLDYLSYAVYQQGDLDKALLLTKKLLELDPEHQRANGNLKYFEYIM-AKEKDVNKSA 262
K S +YL A ++ L+KA+ +PEH NL Y++ + KE D
Sbjct: 142 KRSPYNYLQVAYFKINKLEKAVAAAHTFFVGNPEHMEMQQNLDYYQTMSGVKEADFKDLE 201
Query: 263 S--------------DDQSDQKTTPKKKGVAVDYLPERQKYEMLCRG 295
+ ++ Q+ P + +Y ++ LC G
Sbjct: 202 TQPHMQEFRLGVRLYSEEQPQEAVPHLEAALQEYFVAYEECRALCEG 248
>gi|190194412 thyroid hormone receptor interactor 11 [Homo sapiens]
Length = 1979
Score = 30.8 bits (68), Expect = 3.1
Identities = 45/197 (22%), Positives = 79/197 (40%), Gaps = 25/197 (12%)
Query: 169 ELGKVAYTEADYYHTELWMEQALRQLDEGEISTIDKVSVLDYLSYA-----VYQQG---- 219
EL + E D + E+ + Q Q EIS + + DY + QQG
Sbjct: 220 ELKQNRSQEIDDHQHEMSVLQNAHQQKLTEISRRHREELSDYEERIEELENLLQQGGSGV 279
Query: 220 ---DLDKALLLTKKLLELDPEHQRANGNLKYFEYIMAKEKDVNKSASDDQSDQKTTPKKK 276
DL K + K + L E + K E + K KD+NK S ++D+ +++
Sbjct: 280 IETDLSKIYEMQKTIQVLQIEKVEST---KKMEQLEDKIKDINKKLSSAENDRDILRREQ 336
Query: 277 GVAVDYLPERQKYEMLCRGEGIKMTPRRQKKLFCRYHDGNRNPKFILAPAKQEDEWDKPR 336
+K +++ E +K+ + + + D + ILA + +E
Sbjct: 337 EQL-----NVEKRQIMEECENLKLECSKLQPSAVKQSDTMTEKERILAQSASVEE----- 386
Query: 337 IIRFHDIISDAEIEIVK 353
+ R +SDAE EI++
Sbjct: 387 VFRLQQALSDAENEIMR 403
>gi|221316624 dystonin isoform 4 [Homo sapiens]
Length = 5526
Score = 30.4 bits (67), Expect = 4.1
Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 7/63 (11%)
Query: 17 AHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWAEK-------LDRLTST 69
A+ G + MTD+ H +DL LKD I KL +++K E+ L ++ T
Sbjct: 2419 ANKGLTSIKKDMTDISHGYEDLGLLLKDKIAELNTKLSKLQKAQEESSAMMQWLQKMNKT 2478
Query: 70 ATK 72
ATK
Sbjct: 2479 ATK 2481
>gi|221316622 dystonin isoform 3 [Homo sapiens]
Length = 5537
Score = 30.4 bits (67), Expect = 4.1
Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 7/63 (11%)
Query: 17 AHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWAEK-------LDRLTST 69
A+ G + MTD+ H +DL LKD I KL +++K E+ L ++ T
Sbjct: 2430 ANKGLTSIKKDMTDISHGYEDLGLLLKDKIAELNTKLSKLQKAQEESSAMMQWLQKMNKT 2489
Query: 70 ATK 72
ATK
Sbjct: 2490 ATK 2492
>gi|221316618 dystonin isoform 2 [Homo sapiens]
Length = 5675
Score = 30.4 bits (67), Expect = 4.1
Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 7/63 (11%)
Query: 17 AHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWAEK-------LDRLTST 69
A+ G + MTD+ H +DL LKD I KL +++K E+ L ++ T
Sbjct: 2568 ANKGLTSIKKDMTDISHGYEDLGLLLKDKIAELNTKLSKLQKAQEESSAMMQWLQKMNKT 2627
Query: 70 ATK 72
ATK
Sbjct: 2628 ATK 2630
>gi|34577047 dystonin isoform 1 [Homo sapiens]
Length = 5497
Score = 30.4 bits (67), Expect = 4.1
Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 7/63 (11%)
Query: 17 AHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWAEK-------LDRLTST 69
A+ G + MTD+ H +DL LKD I KL +++K E+ L ++ T
Sbjct: 2390 ANKGLTSIKKDMTDISHGYEDLGLLLKDKIAELNTKLSKLQKAQEESSAMMQWLQKMNKT 2449
Query: 70 ATK 72
ATK
Sbjct: 2450 ATK 2452
>gi|34577049 dystonin isoform 1eA precursor [Homo sapiens]
Length = 5171
Score = 30.4 bits (67), Expect = 4.1
Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 7/63 (11%)
Query: 17 AHPGFFTSIGQMTDLIHTEKDLVTSLKDYIKAEEDKLEQIKKWAEK-------LDRLTST 69
A+ G + MTD+ H +DL LKD I KL +++K E+ L ++ T
Sbjct: 2064 ANKGLTSIKKDMTDISHGYEDLGLLLKDKIAELNTKLSKLQKAQEESSAMMQWLQKMNKT 2123
Query: 70 ATK 72
ATK
Sbjct: 2124 ATK 2126
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 30.4 bits (67), Expect = 4.1
Identities = 26/108 (24%), Positives = 45/108 (41%), Gaps = 14/108 (12%)
Query: 32 IHTEKDLVTSLKDYIKAEEDKLEQIKKWAEKLDRLTSTATKDPEGFVGHPVNAFKLMKRL 91
+ EK LKD +K EE++L+ K++ EK +L S + G H N KL ++
Sbjct: 1186 VEQEKRNQQILKDQVKKEEEELK--KEFIEKEAKLHSEIKEKEVGMKKHEENEAKLTMQI 1243
Query: 92 NT----------EWSELENLV--LKDMSDGFISNLTIQRQYFPNDEDQ 127
EW + V L+ +D + + N++D+
Sbjct: 1244 TALNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDE 1291
>gi|157739936 chromosome 10 open reading frame 68 [Homo sapiens]
Length = 628
Score = 30.4 bits (67), Expect = 4.1
Identities = 16/55 (29%), Positives = 29/55 (52%)
Query: 329 EDEWDKPRIIRFHDIISDAEIEIVKDLAKPRLSRATVHDPETGKLTTAQYRVSKS 383
++E K ++ D +S E++I K PR R + HD E+G+ +++ S S
Sbjct: 91 DEEPGKNLVLEHQDSVSKLEMQIEKTKKLPREKRHSTHDEESGENPMLKHQDSVS 145
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,946,978
Number of Sequences: 37866
Number of extensions: 886225
Number of successful extensions: 2517
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 2438
Number of HSP's gapped (non-prelim): 83
length of query: 516
length of database: 18,247,518
effective HSP length: 107
effective length of query: 409
effective length of database: 14,195,856
effective search space: 5806105104
effective search space used: 5806105104
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.