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Search of human proteins with 216548478
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|216548478 synaptotagmin XI [Homo sapiens]
(431 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|216548478 synaptotagmin XI [Homo sapiens] 865 0.0
gi|24308219 synaptotagmin IV [Homo sapiens] 446 e-125
gi|92859638 synaptotagmin V [Homo sapiens] 233 3e-61
gi|211059429 synaptotagmin II [Homo sapiens] 231 1e-60
gi|31543670 synaptotagmin II [Homo sapiens] 231 1e-60
gi|209447073 synaptotagmin I [Homo sapiens] 230 2e-60
gi|5032139 synaptotagmin I [Homo sapiens] 230 2e-60
gi|209447070 synaptotagmin I [Homo sapiens] 230 2e-60
gi|38570146 synaptotagmin VII [Homo sapiens] 228 6e-60
gi|45504376 synaptotagmin VI [Homo sapiens] 217 1e-56
gi|39752671 synaptotagmin X [Homo sapiens] 216 3e-56
gi|238550198 synaptotagmin III [Homo sapiens] 211 8e-55
gi|238550196 synaptotagmin III [Homo sapiens] 211 8e-55
gi|14150054 synaptotagmin III [Homo sapiens] 211 8e-55
gi|28376627 synaptotagmin IX [Homo sapiens] 207 1e-53
gi|40068038 B/K protein [Homo sapiens] 174 1e-43
gi|6005997 double C2-like domains, beta [Homo sapiens] 167 2e-41
gi|47078261 double C2-like domains, alpha [Homo sapiens] 140 3e-33
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens] 138 1e-32
gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens] 138 1e-32
gi|94536846 synaptotagmin VIII [Homo sapiens] 127 2e-29
gi|31881675 synaptotagmin XV isoform a [Homo sapiens] 127 3e-29
gi|29366828 synaptotagmin XII [Homo sapiens] 123 4e-28
gi|24308233 synaptotagmin XIII [Homo sapiens] 111 1e-24
gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens] 107 2e-23
gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens] 107 2e-23
gi|193804862 synaptotagmin-like 4 [Homo sapiens] 104 2e-22
gi|193804860 synaptotagmin-like 4 [Homo sapiens] 104 2e-22
gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo sap... 100 2e-21
gi|31881667 synaptotagmin XV isoform b [Homo sapiens] 100 4e-21
>gi|216548478 synaptotagmin XI [Homo sapiens]
Length = 431
Score = 865 bits (2235), Expect = 0.0
Identities = 431/431 (100%), Positives = 431/431 (100%)
Query: 1 MAEITNIRPSFDVSPVVAGLIGASVLVVCVSVTVFVWSCCHQQAEKKQKNPPYKFIHMLK 60
MAEITNIRPSFDVSPVVAGLIGASVLVVCVSVTVFVWSCCHQQAEKKQKNPPYKFIHMLK
Sbjct: 1 MAEITNIRPSFDVSPVVAGLIGASVLVVCVSVTVFVWSCCHQQAEKKQKNPPYKFIHMLK 60
Query: 61 GISIYPETLSNKKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCID 120
GISIYPETLSNKKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCID
Sbjct: 61 GISIYPETLSNKKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCID 120
Query: 121 QLPIKMDYGEELRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQE 180
QLPIKMDYGEELRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQE
Sbjct: 121 QLPIKMDYGEELRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQE 180
Query: 181 AHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDL 240
AHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDL
Sbjct: 181 AHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDL 240
Query: 241 VLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLS 300
VLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLS
Sbjct: 241 VLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLS 300
Query: 301 YQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFN 360
YQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFN
Sbjct: 301 YQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFN 360
Query: 361 ESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRK 420
ESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRK
Sbjct: 361 ESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRK 420
Query: 421 PVAKWHSLSEY 431
PVAKWHSLSEY
Sbjct: 421 PVAKWHSLSEY 431
>gi|24308219 synaptotagmin IV [Homo sapiens]
Length = 425
Score = 446 bits (1147), Expect = e-125
Identities = 228/432 (52%), Positives = 307/432 (71%), Gaps = 10/432 (2%)
Query: 1 MAEITNIRPSFDVSPVVAGLIGASVLVVCVSVTVFVWSCCHQQAEKKQKNPPYKFIHMLK 60
MA IT R FD P V G+ A LV VS+ F W CC +++ K K PPYKF+H+LK
Sbjct: 1 MAPITTSREEFDEIPTVVGIFSAFGLVFTVSL--FAWICCQRKSSKSNKTPPYKFVHVLK 58
Query: 61 GISIYPETLSNKKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSR-DKDPRGPSSGSCI 119
G+ IYPE L++KKK +++ + +L +D + L K P S S +
Sbjct: 59 GVDIYPENLNSKKKFGADDKNEVKNKPAVPKNSLHLDLEKRDLNGNFPKTNLKPGSPSDL 118
Query: 120 DQLPIKMDYGEELRSPITSLTPGESKT-TSPSSPEEDVMLGSLTFSVDYNFPKKALVVTI 178
+ K+ L S++P K+ TS +S E+ LG+L FS++YNF +KA VV I
Sbjct: 119 ENATPKLF----LEGEKESVSPESLKSSTSLTSEEKQEKLGTLFFSLEYNFERKAFVVNI 174
Query: 179 QEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQ 238
+EA GLP MD+Q+ SDPYIKMTILP+K+H+VKTRVLRKTLDP FDETFTFYGIPY+Q+Q
Sbjct: 175 KEARGLPAMDEQSMTSDPYIKMTILPEKKHKVKTRVLRKTLDPAFDETFTFYGIPYTQIQ 234
Query: 239 DLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVS 298
+L LHF +LSFDRFSRDD+IGEV++PL+G++ S GK+ + R+IIKRN++K RGEL +S
Sbjct: 235 ELALHFTILSFDRFSRDDIIGEVLIPLSGIELSEGKMLMNREIIKRNVRKSSGRGELLIS 294
Query: 299 LSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPI 358
L YQ +TVVVLKARHLPK D++GLS +PYVKVN+Y+ +KRI+KKKTHVKKCT N +
Sbjct: 295 LCYQSTTNTLTVVVLKARHLPKSDVSGLS-DPYVKVNLYHAKKRISKKKTHVKKCTPNAV 353
Query: 359 FNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESP 418
FNE F++DIP + L DIS+EFLV+D +R ++NEV+G+L+LGA + +G EHW+E+C+ P
Sbjct: 354 FNELFVFDIPCEGLEDISVEFLVLDSERGSRNEVIGQLVLGA-AAEGTGGEHWKEICDYP 412
Query: 419 RKPVAKWHSLSE 430
R+ +AKWH L +
Sbjct: 413 RRQIAKWHVLCD 424
>gi|92859638 synaptotagmin V [Homo sapiens]
Length = 386
Score = 233 bits (593), Expect = 3e-61
Identities = 126/290 (43%), Positives = 188/290 (64%), Gaps = 9/290 (3%)
Query: 143 ESKTTSPSSPEEDVM----LGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYI 198
E +PS P + V LG L +S+DY+F L+V I +A GL +D SDPY+
Sbjct: 90 EELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALD-LGGSSDPYV 148
Query: 199 KMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVI 258
++ +LPDKR R +T+V R+TL+P F ETF F +PY +L VL V FDRFSR+D I
Sbjct: 149 RVYLLPDKRRRYETKVHRQTLNPHFGETFAFK-VPYVELGGRVLVMAVYDFDRFSRNDAI 207
Query: 259 GEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHL 318
GEV VP++ VD VQ R++ ++ G++ SL Y P A ++TV+VL+A++L
Sbjct: 208 GEVRVPMSSVDLGR-PVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNL 266
Query: 319 PKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIE 378
KMD+ GLS +PYVKV++ G K++ KKKT +KK TLNP +NE+F +++P D + + +E
Sbjct: 267 KKMDVGGLS-DPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVE 325
Query: 379 FLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSL 428
V+D+D+ KNE +GR+ +GA + +G HW ++ +PR+P+A+WHSL
Sbjct: 326 LTVLDYDKLGKNEAIGRVAVGA-AAGGAGLRHWADMLANPRRPIAQWHSL 374
>gi|211059429 synaptotagmin II [Homo sapiens]
Length = 419
Score = 231 bits (589), Expect = 1e-60
Identities = 125/303 (41%), Positives = 190/303 (62%), Gaps = 8/303 (2%)
Query: 126 MDYGEELRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLP 185
M G++ T LT GE + PE LG L FS+DY+F L V + +A LP
Sbjct: 111 MKGGQDDDDAETGLTEGEGEGEEEKEPEN---LGKLQFSLDYDFQANQLTVGVLQAAELP 167
Query: 186 VMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFL 245
+D SDPY+K+ +LPDK+ + +T+V RKTL+P F+ETFTF +PY +L L
Sbjct: 168 ALD-MGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMA 225
Query: 246 VLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVA 305
+ FDRFS+ D+IGEV VP+ VD ++ RD+ ++ G++ SL Y P A
Sbjct: 226 IYDFDRFSKHDIIGEVKVPMNTVDLGQ-PIEEWRDLQGGEKEEPEKLGDICTSLRYVPTA 284
Query: 306 QRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIY 365
++TV +L+A++L KMD+ GLS +PYVK+++ KR+ KKKT VKK TLNP FNESF +
Sbjct: 285 GKLTVCILEAKNLKKMDVGGLS-DPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSF 343
Query: 366 DIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKW 425
+IP + + + + V+D+D+ KNE +G++ +G+++ T + HW ++ +PR+P+A+W
Sbjct: 344 EIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNA-TGTELRHWSDMLANPRRPIAQW 402
Query: 426 HSL 428
HSL
Sbjct: 403 HSL 405
>gi|31543670 synaptotagmin II [Homo sapiens]
Length = 419
Score = 231 bits (589), Expect = 1e-60
Identities = 125/303 (41%), Positives = 190/303 (62%), Gaps = 8/303 (2%)
Query: 126 MDYGEELRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLP 185
M G++ T LT GE + PE LG L FS+DY+F L V + +A LP
Sbjct: 111 MKGGQDDDDAETGLTEGEGEGEEEKEPEN---LGKLQFSLDYDFQANQLTVGVLQAAELP 167
Query: 186 VMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFL 245
+D SDPY+K+ +LPDK+ + +T+V RKTL+P F+ETFTF +PY +L L
Sbjct: 168 ALD-MGGTSDPYVKVFLLPDKKKKYETKVHRKTLNPAFNETFTFK-VPYQELGGKTLVMA 225
Query: 246 VLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVA 305
+ FDRFS+ D+IGEV VP+ VD ++ RD+ ++ G++ SL Y P A
Sbjct: 226 IYDFDRFSKHDIIGEVKVPMNTVDLGQ-PIEEWRDLQGGEKEEPEKLGDICTSLRYVPTA 284
Query: 306 QRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIY 365
++TV +L+A++L KMD+ GLS +PYVK+++ KR+ KKKT VKK TLNP FNESF +
Sbjct: 285 GKLTVCILEAKNLKKMDVGGLS-DPYVKIHLMQNGKRLKKKKTTVKKKTLNPYFNESFSF 343
Query: 366 DIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKW 425
+IP + + + + V+D+D+ KNE +G++ +G+++ T + HW ++ +PR+P+A+W
Sbjct: 344 EIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFVGSNA-TGTELRHWSDMLANPRRPIAQW 402
Query: 426 HSL 428
HSL
Sbjct: 403 HSL 405
>gi|209447073 synaptotagmin I [Homo sapiens]
Length = 422
Score = 230 bits (586), Expect = 2e-60
Identities = 136/358 (37%), Positives = 210/358 (58%), Gaps = 31/358 (8%)
Query: 72 KKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCIDQLPIKMDYGEE 131
KK + K + K G + G + D + G +D+ +K D E
Sbjct: 81 KKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQ--------------ALKDDDAE- 125
Query: 132 LRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQT 191
T LT GE K P+E+ LG L +S+DY+F L+V I +A LP +D
Sbjct: 126 -----TGLTDGEEK----EEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALD-MG 175
Query: 192 QGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDR 251
SDPY+K+ +LPDK+ + +T+V RKTL+PVF+E FTF +PYS+L L V FDR
Sbjct: 176 GTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDR 234
Query: 252 FSRDDVIGEVMVPLAGVDPSTGKV-QLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTV 310
FS+ D+IGE VP+ VD G V + RD+ ++ G++ SL Y P A ++TV
Sbjct: 235 FSKHDIIGEFKVPMNTVD--FGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTV 292
Query: 311 VVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTD 370
V+L+A++L KMD+ GLS +PYVK+++ KR+ KKKT +KK TLNP +NESF +++P +
Sbjct: 293 VILEAKNLKKMDVGGLS-DPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFE 351
Query: 371 LLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSL 428
+ + + V+D+D+ KN+ +G++ +G +S T + HW ++ +PR+P+A+WH+L
Sbjct: 352 QIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNS-TGAELRHWSDMLANPRRPIAQWHTL 408
>gi|5032139 synaptotagmin I [Homo sapiens]
Length = 422
Score = 230 bits (586), Expect = 2e-60
Identities = 136/358 (37%), Positives = 210/358 (58%), Gaps = 31/358 (8%)
Query: 72 KKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCIDQLPIKMDYGEE 131
KK + K + K G + G + D + G +D+ +K D E
Sbjct: 81 KKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQ--------------ALKDDDAE- 125
Query: 132 LRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQT 191
T LT GE K P+E+ LG L +S+DY+F L+V I +A LP +D
Sbjct: 126 -----TGLTDGEEK----EEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALD-MG 175
Query: 192 QGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDR 251
SDPY+K+ +LPDK+ + +T+V RKTL+PVF+E FTF +PYS+L L V FDR
Sbjct: 176 GTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDR 234
Query: 252 FSRDDVIGEVMVPLAGVDPSTGKV-QLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTV 310
FS+ D+IGE VP+ VD G V + RD+ ++ G++ SL Y P A ++TV
Sbjct: 235 FSKHDIIGEFKVPMNTVD--FGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTV 292
Query: 311 VVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTD 370
V+L+A++L KMD+ GLS +PYVK+++ KR+ KKKT +KK TLNP +NESF +++P +
Sbjct: 293 VILEAKNLKKMDVGGLS-DPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFE 351
Query: 371 LLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSL 428
+ + + V+D+D+ KN+ +G++ +G +S T + HW ++ +PR+P+A+WH+L
Sbjct: 352 QIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNS-TGAELRHWSDMLANPRRPIAQWHTL 408
>gi|209447070 synaptotagmin I [Homo sapiens]
Length = 422
Score = 230 bits (586), Expect = 2e-60
Identities = 136/358 (37%), Positives = 210/358 (58%), Gaps = 31/358 (8%)
Query: 72 KKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCIDQLPIKMDYGEE 131
KK + K + K G + G + D + G +D+ +K D E
Sbjct: 81 KKCLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQ--------------ALKDDDAE- 125
Query: 132 LRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQT 191
T LT GE K P+E+ LG L +S+DY+F L+V I +A LP +D
Sbjct: 126 -----TGLTDGEEK----EEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALD-MG 175
Query: 192 QGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDR 251
SDPY+K+ +LPDK+ + +T+V RKTL+PVF+E FTF +PYS+L L V FDR
Sbjct: 176 GTSDPYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFK-VPYSELGGKTLVMAVYDFDR 234
Query: 252 FSRDDVIGEVMVPLAGVDPSTGKV-QLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTV 310
FS+ D+IGE VP+ VD G V + RD+ ++ G++ SL Y P A ++TV
Sbjct: 235 FSKHDIIGEFKVPMNTVD--FGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTV 292
Query: 311 VVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTD 370
V+L+A++L KMD+ GLS +PYVK+++ KR+ KKKT +KK TLNP +NESF +++P +
Sbjct: 293 VILEAKNLKKMDVGGLS-DPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFE 351
Query: 371 LLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSL 428
+ + + V+D+D+ KN+ +G++ +G +S T + HW ++ +PR+P+A+WH+L
Sbjct: 352 QIQKVQVVVTVLDYDKIGKNDAIGKVFVGYNS-TGAELRHWSDMLANPRRPIAQWHTL 408
>gi|38570146 synaptotagmin VII [Homo sapiens]
Length = 403
Score = 228 bits (582), Expect = 6e-60
Identities = 156/427 (36%), Positives = 236/427 (55%), Gaps = 45/427 (10%)
Query: 9 PSFDVSPVVAGLIGASVLVVCVSVTVFVWSCCHQQAEKKQKNPPYKFIHMLKGISIYPET 68
PS DV L+ ++++ V +SVTV + CH K K ++ + L+ + P++
Sbjct: 13 PSRDV------LLVSAIITVSLSVTVVLCGLCHWCQRKLGK----RYKNSLETVGT-PDS 61
Query: 69 --LSNKKKIIKVRRDKDGPGREGGRRNLLVDAAEAGLLSRDKDPRGPSSGSCIDQLPIKM 126
++KK IK+ GG+ + A G D+ R S +
Sbjct: 62 GRGRSEKKAIKL--------PAGGK--AVNTAPVPGQTPHDESDRRTEPRSSVS------ 105
Query: 127 DYGEELRSPITSLTPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPV 186
D L S + L+PG + + + LG + FSV YNF + L V I +A LP
Sbjct: 106 DLVNSLTSEMLMLSPGSEEDEAHEGCSRE-NLGRIQFSVGYNFQESTLTVKIMKAQELPA 164
Query: 187 MDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLV 246
D + SDP++K+ +LPDK+H+++T+V RK L+P ++ETF F G PY ++ +L+ V
Sbjct: 165 -KDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQV 223
Query: 247 LSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTR-DIIKRNIQKCI----SRGELQVSLSY 301
L +DRFSR+D IGEV +PL KV LT+ ++++ C SRGEL +SL Y
Sbjct: 224 LDYDRFSRNDPIGEVSIPL-------NKVDLTQMQTFWKDLKPCSDGSGSRGELLLSLCY 276
Query: 302 QPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNE 361
P A + V ++KAR+L MDI G S +PYVKV + Y KR+ KKKT K LNPIFNE
Sbjct: 277 NPSANSIIVNIIKARNLKAMDIGGTS-DPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNE 335
Query: 362 SFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKP 421
SF +DIPT+ L + +I V+D D+ ++N+V+G++ L S +HW+++ PR+P
Sbjct: 336 SFAFDIPTEKLRETTIIITVMDKDKLSRNDVIGKIYLSWKSGPGE-VKHWKDMIARPRQP 394
Query: 422 VAKWHSL 428
VA+WH L
Sbjct: 395 VAQWHQL 401
>gi|45504376 synaptotagmin VI [Homo sapiens]
Length = 425
Score = 217 bits (553), Expect = 1e-56
Identities = 127/316 (40%), Positives = 187/316 (59%), Gaps = 16/316 (5%)
Query: 126 MDYGEELR------SPITSLTPGESKTTS----PSSPEEDVMLGSLTFSVDYNFPKKALV 175
+DYG EL + I + P K S + E G + FS+ Y++ + L+
Sbjct: 103 VDYGNELPPAAEQPTSIGRIKPELYKQKSVDGEDAKSEATKSCGKINFSLRYDYETETLI 162
Query: 176 VTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYS 235
V I +A LP D SDPY+K+ +LPD++ +++TRV RKTL+P FDE F F +PY
Sbjct: 163 VRILKAFDLPAKDF-CGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHF-PVPYE 220
Query: 236 QLQDLVLHFLVLSFDRFSRDDVIGEVMVP-LAGVDPSTGKVQLTRDIIKRNIQKCISRGE 294
+L D LH V FDRFSR D+IGEV++ L + + + +DI + + + GE
Sbjct: 221 ELADRKLHLSVFDFDRFSRHDMIGEVILDNLFEASDLSRETSIWKDI-QYATSESVDLGE 279
Query: 295 LQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCT 354
+ SL Y P A R+T+ V+K R+L MDITG S +PYVKV++ +R+ KKKT +KK T
Sbjct: 280 IMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYS-DPYVKVSLLCDGRRLKKKKTTIKKNT 338
Query: 355 LNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREV 414
LNP++NE+ I+DIP + + +S+ V+D+DR NE++G +G + G +HW E+
Sbjct: 339 LNPVYNEAIIFDIPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGI-TAEGLGRDHWNEM 397
Query: 415 CESPRKPVAKWHSLSE 430
PRKP+A WHSL E
Sbjct: 398 LAYPRKPIAHWHSLVE 413
>gi|39752671 synaptotagmin X [Homo sapiens]
Length = 523
Score = 216 bits (550), Expect = 3e-56
Identities = 125/290 (43%), Positives = 176/290 (60%), Gaps = 7/290 (2%)
Query: 143 ESKTTSPSSPEEDVML-GSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMT 201
+ S + EDV + G L F++ Y++ + LVV I +A LP D T SDPY+KM
Sbjct: 216 QKSVDSEGNQNEDVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDF-TGTSDPYVKMY 274
Query: 202 ILPDKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEV 261
+LPD++ + +TRV RKTL+P+FDETF F + Y QL + LHF V FDRFSR D+IGEV
Sbjct: 275 LLPDRKKKFQTRVHRKTLNPLFDETFQF-PVAYDQLSNRKLHFSVYDFDRFSRHDMIGEV 333
Query: 262 MVP-LAGVDPSTGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPK 320
++ L V + + + +DI + I GE+ SL Y P A RMT+ V+K R+L
Sbjct: 334 ILDNLFEVSDLSREATVWKDIHCATTES-IDLGEIMFSLCYLPTAGRMTLTVIKCRNLKA 392
Query: 321 MDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFL 380
MDITG S +PYVKV++ +R+ K+KT KK TLNP++NE+ I+DIP + + +S+
Sbjct: 393 MDITG-SSDPYVKVSLMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIA 451
Query: 381 VIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSLSE 430
V+D+DR NEV+G G G +HW E+ RKP+ WH L E
Sbjct: 452 VMDYDRVGHNEVIGVCRTGL-DAEGLGRDHWNEMLAYHRKPITHWHPLLE 500
>gi|238550198 synaptotagmin III [Homo sapiens]
Length = 590
Score = 211 bits (538), Expect = 8e-55
Identities = 128/333 (38%), Positives = 186/333 (55%), Gaps = 22/333 (6%)
Query: 113 PSSGSCIDQLPIKMDYGEELRSPITSLTP---------GESKTTSPSSPEEDV--MLGSL 161
PSS LP+ + GEE I + P G P S E G +
Sbjct: 244 PSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCGRI 303
Query: 162 TFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDP 221
+F++ Y + LVV I +A LP D SDPY+K+ +LPD++ + +T+V RKTL+P
Sbjct: 304 SFALRYLYGSDQLVVRILQALDLPAKDSNGF-SDPYVKIYLLPDRKKKFQTKVHRKTLNP 362
Query: 222 VFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEV----MVPLAGVDPSTGKVQL 277
VF+ETF F +P ++L LHF V FDRFSR D+IG+V ++ LA P L
Sbjct: 363 VFNETFQF-SVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDR---PL 418
Query: 278 TRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVY 337
RDI++ +K GEL SL Y P A R+TV ++KA +L MD+TG S +PYVK ++
Sbjct: 419 WRDIVEGGSEKA-DLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFS-DPYVKASLI 476
Query: 338 YGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLI 397
+R+ K+KT +KK TLNP +NE+ ++D+ + + ++ + V+D+D NEV+G
Sbjct: 477 SEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCR 536
Query: 398 LGAHSVTASGAEHWREVCESPRKPVAKWHSLSE 430
+G + G EHW E+ +PRKPV WH L E
Sbjct: 537 VGPDAADPHGREHWAEMLANPRKPVEHWHQLVE 569
>gi|238550196 synaptotagmin III [Homo sapiens]
Length = 590
Score = 211 bits (538), Expect = 8e-55
Identities = 128/333 (38%), Positives = 186/333 (55%), Gaps = 22/333 (6%)
Query: 113 PSSGSCIDQLPIKMDYGEELRSPITSLTP---------GESKTTSPSSPEEDV--MLGSL 161
PSS LP+ + GEE I + P G P S E G +
Sbjct: 244 PSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCGRI 303
Query: 162 TFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDP 221
+F++ Y + LVV I +A LP D SDPY+K+ +LPD++ + +T+V RKTL+P
Sbjct: 304 SFALRYLYGSDQLVVRILQALDLPAKDSNGF-SDPYVKIYLLPDRKKKFQTKVHRKTLNP 362
Query: 222 VFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEV----MVPLAGVDPSTGKVQL 277
VF+ETF F +P ++L LHF V FDRFSR D+IG+V ++ LA P L
Sbjct: 363 VFNETFQF-SVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDR---PL 418
Query: 278 TRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVY 337
RDI++ +K GEL SL Y P A R+TV ++KA +L MD+TG S +PYVK ++
Sbjct: 419 WRDIVEGGSEKA-DLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFS-DPYVKASLI 476
Query: 338 YGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLI 397
+R+ K+KT +KK TLNP +NE+ ++D+ + + ++ + V+D+D NEV+G
Sbjct: 477 SEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCR 536
Query: 398 LGAHSVTASGAEHWREVCESPRKPVAKWHSLSE 430
+G + G EHW E+ +PRKPV WH L E
Sbjct: 537 VGPDAADPHGREHWAEMLANPRKPVEHWHQLVE 569
>gi|14150054 synaptotagmin III [Homo sapiens]
Length = 590
Score = 211 bits (538), Expect = 8e-55
Identities = 128/333 (38%), Positives = 186/333 (55%), Gaps = 22/333 (6%)
Query: 113 PSSGSCIDQLPIKMDYGEELRSPITSLTP---------GESKTTSPSSPEEDV--MLGSL 161
PSS LP+ + GEE I + P G P S E G +
Sbjct: 244 PSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGTGAPCGRI 303
Query: 162 TFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKTLDP 221
+F++ Y + LVV I +A LP D SDPY+K+ +LPD++ + +T+V RKTL+P
Sbjct: 304 SFALRYLYGSDQLVVRILQALDLPAKDSNGF-SDPYVKIYLLPDRKKKFQTKVHRKTLNP 362
Query: 222 VFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEV----MVPLAGVDPSTGKVQL 277
VF+ETF F +P ++L LHF V FDRFSR D+IG+V ++ LA P L
Sbjct: 363 VFNETFQF-SVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDR---PL 418
Query: 278 TRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVY 337
RDI++ +K GEL SL Y P A R+TV ++KA +L MD+TG S +PYVK ++
Sbjct: 419 WRDIVEGGSEKA-DLGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFS-DPYVKASLI 476
Query: 338 YGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLI 397
+R+ K+KT +KK TLNP +NE+ ++D+ + + ++ + V+D+D NEV+G
Sbjct: 477 SEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIGVCR 536
Query: 398 LGAHSVTASGAEHWREVCESPRKPVAKWHSLSE 430
+G + G EHW E+ +PRKPV WH L E
Sbjct: 537 VGPDAADPHGREHWAEMLANPRKPVEHWHQLVE 569
>gi|28376627 synaptotagmin IX [Homo sapiens]
Length = 491
Score = 207 bits (527), Expect = 1e-53
Identities = 115/277 (41%), Positives = 171/277 (61%), Gaps = 14/277 (5%)
Query: 159 GSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLRKT 218
G L F + Y+ + L+V I +A LP D SDPY+K+ +LPD++ + +T+V RKT
Sbjct: 222 GKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGT-SDPYVKIYLLPDRKTKHQTKVHRKT 280
Query: 219 LDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLT 278
L+PVFDE F F +PY+ L+ LHF V FDRFSR D+IG+V+V D
Sbjct: 281 LNPVFDEVFLF-PVPYNDLEARKLHFSVYDFDRFSRHDLIGQVVV-----DHFLDLADFP 334
Query: 279 RD-IIKRNIQKC----ISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVK 333
R+ I+ ++I+ + GEL SL Y P A R+T+ ++KAR+L MDITG S +PYVK
Sbjct: 335 RECILWKDIEYVTNDNVDLGELMFSLCYLPTAGRLTITIIKARNLKAMDITGAS-DPYVK 393
Query: 334 VNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVV 393
V++ +R+ K+KT K+ TLNP++NE+ ++D+P + + I + V+D+DR NE++
Sbjct: 394 VSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQIHLSIAVMDYDRVGHNEII 453
Query: 394 GRLILGAHSVTASGAEHWREVCESPRKPVAKWHSLSE 430
G +G + G +HW E+ PRKP+A WHSL E
Sbjct: 454 GVCQVG-NEAERLGRDHWSEMLSYPRKPIAHWHSLVE 489
Score = 62.8 bits (151), Expect = 6e-10
Identities = 39/112 (34%), Positives = 61/112 (54%), Gaps = 4/112 (3%)
Query: 154 EDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRH--RVK 211
++V LG L FS+ Y L +TI +A L M D T SDPY+K++++ D R + K
Sbjct: 349 DNVDLGELMFSLCYLPTAGRLTITIIKARNLKAM-DITGASDPYVKVSLMCDGRRLKKRK 407
Query: 212 TRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMV 263
T R TL+PV++E F +P + + L V+ +DR +++IG V
Sbjct: 408 TSTKRNTLNPVYNEAIVF-DVPPENIDQIHLSIAVMDYDRVGHNEIIGVCQV 458
>gi|40068038 B/K protein [Homo sapiens]
Length = 474
Score = 174 bits (441), Expect = 1e-43
Identities = 116/337 (34%), Positives = 182/337 (54%), Gaps = 15/337 (4%)
Query: 100 EAGLLSRDKDPRGPSSGSCIDQLPIKMDYGEELRSPITSLTPGESKTTSPSSPE--EDVM 157
E G+LS K+P PS + + DY + + SL S + E
Sbjct: 128 EFGVLSAKKEPIQPS---VLRRTYNPDDYFRKFEPHLYSLDSNSDDVDSLTDEEILSKYQ 184
Query: 158 LGSLTFSVDYNFPKKALVVTIQEAHGLP--VMDDQTQG----SDPYIKMTILPDKRHRVK 211
LG L FS Y+ L V + EA LP + D ++ S+PY+K+ +LPD+++ +
Sbjct: 185 LGMLHFSTQYDLLHNHLTVRVIEARDLPPPISHDGSRQDMAHSNPYVKICLLPDQKNSKQ 244
Query: 212 TRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPS 271
T V RKT PVF+E +TF IP+ + Q L V+ FD+FSR VIG+V VPL VD
Sbjct: 245 TGVKRKTQKPVFEERYTFE-IPFLEAQRRTLLLTVVDFDKFSRHCVIGKVSVPLCEVDLV 303
Query: 272 TGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPY 331
G + +I + Q + GEL +SL+Y P A R+ V V++A+ L + D++ S +P+
Sbjct: 304 KGG-HWWKALIPSS-QNEVELGELLLSLNYLPSAGRLNVDVIRAKQLLQTDVSQGS-DPF 360
Query: 332 VKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNE 391
VK+ + +G K + KKT + T++P +NESF + +P + L + S+ F V + + N+
Sbjct: 361 VKIQLVHGLKLVKTKKTSFLRGTIDPFYNESFSFKVPQEELENASLVFTVFGHNMKSSND 420
Query: 392 VVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSL 428
+GR+++G +S S HWR + + R V +WHSL
Sbjct: 421 FIGRIVIGQYSSGPSETNHWRRMLNTHRTAVEQWHSL 457
>gi|6005997 double C2-like domains, beta [Homo sapiens]
Length = 412
Score = 167 bits (422), Expect = 2e-41
Identities = 113/338 (33%), Positives = 170/338 (50%), Gaps = 24/338 (7%)
Query: 111 RGPSSGSCIDQLPIKMDYGEELRSPITSLTPGESKTTSPSSPEED------------VML 158
R PS G+ D + +G SP S PG S P+ P ED L
Sbjct: 70 RSPSDGAREDDEDVDQLFGAYGSSPGPS--PGPSPARPPAKPPEDEPDADGYESDDCTAL 127
Query: 159 GSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILP--DKRHRVKTRVLR 216
G+L FS+ Y+ AL TI +A GL MD +DPY+K+ +LP K ++++T+ LR
Sbjct: 128 GTLDFSLLYDQENNALHCTITKAKGLKPMDHNGL-ADPYVKLHLLPGASKANKLRTKTLR 186
Query: 217 KTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGK-- 274
TL+P ++ET T+YGI + L V D+F ++ IGE VPL + P+ K
Sbjct: 187 NTLNPTWNETLTYYGITDEDMIRKTLRISVCDEDKFRHNEFIGETRVPLKKLKPNHTKTF 246
Query: 275 ---VQLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPY 331
++ + K + RG + +SL Y Q + V +++ HL MD G S +PY
Sbjct: 247 NICLEKQLPVDKTEDKSLEERGRILISLKYSSQKQGLLVGIVRCAHLAAMDANGYS-DPY 305
Query: 332 VKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNE 391
VK + + +K KT VKK TLNP FNE F Y+I L S+E V D+D N+
Sbjct: 306 VKTYLRPDVDKKSKHKTAVKKKTLNPEFNEEFCYEIKHGDLAKKSLEVTVWDYDIGKSND 365
Query: 392 VVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSLS 429
+G ++LG H+ +HW + ++ K + +WH+L+
Sbjct: 366 FIGGVVLGIHA-KGERLKHWFDCLKNKDKRIERWHTLT 402
>gi|47078261 double C2-like domains, alpha [Homo sapiens]
Length = 400
Score = 140 bits (352), Expect = 3e-33
Identities = 99/319 (31%), Positives = 152/319 (47%), Gaps = 32/319 (10%)
Query: 140 TPGESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIK 199
TP + ++ LG+L F + Y+ L +I A GL MD +DPY+K
Sbjct: 72 TPEDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGL-ADPYVK 130
Query: 200 MTILPD--KRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDV 257
+ +LP K +++KT+ R TL+PV++E T+ GI + VL V D+ S ++
Sbjct: 131 LHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEF 190
Query: 258 IGEVMVPLAGVDPSTGK---VQLTRDI----------IKRNIQKCIS------------- 291
IGE+ VPL + PS K + L R + R I +
Sbjct: 191 IGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLE 250
Query: 292 -RGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHV 350
RG + +SLSY + + V +L+ HL MD+ G S +PYVK + + +K KT V
Sbjct: 251 ERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYS-DPYVKTYLRPDVDKKSKHKTCV 309
Query: 351 KKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEH 410
KK TLNP FNE F Y+I L ++E V D+D N+ +G + LG +H
Sbjct: 310 KKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGP-GARGEARKH 368
Query: 411 WREVCESPRKPVAKWHSLS 429
W + + P + +WH+L+
Sbjct: 369 WSDCLQQPDAALERWHTLT 387
>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
Length = 694
Score = 138 bits (347), Expect = 1e-32
Identities = 98/311 (31%), Positives = 152/311 (48%), Gaps = 28/311 (9%)
Query: 143 ESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTI 202
E + + +E LG+L FS+ Y+ +L TI +A GL MD +DPY+K+ +
Sbjct: 378 EEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGL-ADPYVKLHL 436
Query: 203 LP--DKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGE 260
LP K ++++T+ LR T +P+++ET ++GI +Q L V D+F ++ IGE
Sbjct: 437 LPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGE 496
Query: 261 VMVPLAGVDPSTGK---VQLTRDI-IKR-------------------NIQKCISRGELQV 297
L + P+ K + L R I +KR + RG++ V
Sbjct: 497 TRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILV 556
Query: 298 SLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNP 357
SL Y + V +++ HL MD G S +P+VK+ + + AK KT +KK TLNP
Sbjct: 557 SLMYSTQQGGLIVGIIRCVHLAAMDANGYS-DPFVKLWLKPDMGKKAKHKTQIKKKTLNP 615
Query: 358 IFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCES 417
FNE F YDI L S++ V D+D N+ +G LG S +HW E ++
Sbjct: 616 EFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGI-SAKGERLKHWYECLKN 674
Query: 418 PRKPVAKWHSL 428
K + +WH L
Sbjct: 675 KDKKIERWHQL 685
>gi|45267837 rabphilin 3A homolog isoform 2 [Homo sapiens]
Length = 690
Score = 138 bits (347), Expect = 1e-32
Identities = 98/311 (31%), Positives = 152/311 (48%), Gaps = 28/311 (9%)
Query: 143 ESKTTSPSSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTI 202
E + + +E LG+L FS+ Y+ +L TI +A GL MD +DPY+K+ +
Sbjct: 374 EEEEANSYDSDEATTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGL-ADPYVKLHL 432
Query: 203 LP--DKRHRVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGE 260
LP K ++++T+ LR T +P+++ET ++GI +Q L V D+F ++ IGE
Sbjct: 433 LPGASKSNKLRTKTLRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGE 492
Query: 261 VMVPLAGVDPSTGK---VQLTRDI-IKR-------------------NIQKCISRGELQV 297
L + P+ K + L R I +KR + RG++ V
Sbjct: 493 TRFSLKKLKPNQRKNFNICLERVIPMKRAGTTGSARGMALYEEEQVERVGDIEERGKILV 552
Query: 298 SLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNP 357
SL Y + V +++ HL MD G S +P+VK+ + + AK KT +KK TLNP
Sbjct: 553 SLMYSTQQGGLIVGIIRCVHLAAMDANGYS-DPFVKLWLKPDMGKKAKHKTQIKKKTLNP 611
Query: 358 IFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCES 417
FNE F YDI L S++ V D+D N+ +G LG S +HW E ++
Sbjct: 612 EFNEEFFYDIKHSDLAKKSLDISVWDYDIGKSNDYIGGCQLGI-SAKGERLKHWYECLKN 670
Query: 418 PRKPVAKWHSL 428
K + +WH L
Sbjct: 671 KDKKIERWHQL 681
>gi|94536846 synaptotagmin VIII [Homo sapiens]
Length = 401
Score = 127 bits (319), Expect = 2e-29
Identities = 94/288 (32%), Positives = 149/288 (51%), Gaps = 30/288 (10%)
Query: 150 SSPEEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGS-DPYIKMTILPDKRH 208
SSP + G L S++++F + + V +++A L + G+ DPY ++++ H
Sbjct: 110 SSPGDAQQWGRLQLSLEFDFGSQEIRVGLRQAADL-----RPGGTVDPYARVSVSTQAGH 164
Query: 209 RVKTRVLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGV 268
R +T+V R TL PVFDET F+ IP ++L L + +F RFS + +GE+ +PL V
Sbjct: 165 RHETKVHRGTLCPVFDETCCFH-IPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTV 223
Query: 269 DPS--------TGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPK 320
D G T+ GEL SL Y P + R+TVVVL+AR L
Sbjct: 224 DLQHVLEHWYLLGPPAATQPE---------QVGELCFSLRYVPSSGRLTVVVLEARGLRP 274
Query: 321 MDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFL 380
GL+ PYVKV + +++ K+KT KK T P FNE+F + +P + ++ +
Sbjct: 275 ----GLA-EPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLA 329
Query: 381 VIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSL 428
V D + E VG++ LGA + + +HW ++ R+P+A+ H L
Sbjct: 330 VWDRSLPLRTEPVGKVHLGARA-SGQPLQHWADMLAHARRPIAQRHPL 376
>gi|31881675 synaptotagmin XV isoform a [Homo sapiens]
Length = 421
Score = 127 bits (318), Expect = 3e-29
Identities = 84/277 (30%), Positives = 145/277 (52%), Gaps = 9/277 (3%)
Query: 155 DVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRV 214
D LG L FSV+Y + L+V + +A L ++ P +K+ +LPD+R ++++
Sbjct: 145 DGCLGRLWFSVEYEQEAERLLVGLIKAQHLQA---PSETCSPLVKLYLLPDERRFLQSKT 201
Query: 215 LRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGK 274
RKT +P FDE F F + + VL F V DR + ++G+V+ PL + G
Sbjct: 202 KRKTSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKN-ETLVGD 259
Query: 275 VQ--LTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYV 332
+ + RD+ +++ G+LQ LSY R+TVVVL+A+ L + G+ + +V
Sbjct: 260 CRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIV-SVFV 318
Query: 333 KVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEV 392
KV++ K + KKT ++NP++NE+F + L S+ V+ K++
Sbjct: 319 KVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVVQNMEGDKSQQ 378
Query: 393 VGRLILGAHSVT-ASGAEHWREVCESPRKPVAKWHSL 428
+GR+++G + T EHW E+ P++ V +WH+L
Sbjct: 379 LGRVVVGPYMYTRGRELEHWDEMLSKPKELVKRWHAL 415
>gi|29366828 synaptotagmin XII [Homo sapiens]
Length = 421
Score = 123 bits (308), Expect = 4e-28
Identities = 81/279 (29%), Positives = 151/279 (54%), Gaps = 13/279 (4%)
Query: 154 EDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTR 213
+D LG + S++Y+ L V + + L + ++ ++++++LPD++ +R
Sbjct: 149 QDFTLGQVEVSMEYDTASHTLNVAVMQGKDL-LEREEASFESCFMRVSLLPDEQIVGISR 207
Query: 214 VLRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVD---- 269
+ R FDE F+ P + L++ L F V D R+ G V + L+ +D
Sbjct: 208 IQRNAYSIFFDEKFSIPLDP-TALEEKSLRFSVFGIDEDERNVSTGVVELKLSVLDLPLQ 266
Query: 270 PSTGKVQLTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGN 329
P +G + L + + + GE+ +SLSY P A+R+TVVV+KA++L + + +
Sbjct: 267 PFSGWLYL-----QDQNKAADAVGEILLSLSYLPTAERLTVVVVKAKNLIWTN-DKTTAD 320
Query: 330 PYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTK 389
P+VKV + ++++KKKT VK+ NP+FNE+ I+ +P +L D+S+ V + +
Sbjct: 321 PFVKVYLLQDGRKMSKKKTAVKRDDPNPVFNEAMIFSVPAIVLQDLSLRVTVAESSSDGR 380
Query: 390 NEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSL 428
+ VG +I+G S + G HW ++ + R+PV+ WH++
Sbjct: 381 GDNVGHVIIGP-SASGMGTTHWNQMLATLRRPVSMWHAV 418
>gi|24308233 synaptotagmin XIII [Homo sapiens]
Length = 426
Score = 111 bits (277), Expect = 1e-24
Identities = 79/271 (29%), Positives = 137/271 (50%), Gaps = 11/271 (4%)
Query: 161 LTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRH-RVKTRVLRKTL 219
L + +DY+ K L VT EA V + G D Y++ ++ +T + ++ L
Sbjct: 162 LHYCLDYDCQKAELFVTRLEA----VTSNHDGGCDCYVQGSVANRTGSVEAQTALKKRQL 217
Query: 220 DPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQLTR 279
++E + +L L + + DRFSR V GE+ + L G G Q
Sbjct: 218 HTTWEEGLVL-PLAEEELPTATLTLTLRTCDRFSRHSVAGELRLGLDGTSVPLGAAQWGE 276
Query: 280 DIIKRNIQK-CISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPY-VKVNVY 337
+K + ++ GE+ +S+SY P A R+ VV++KA++L L G VKV +
Sbjct: 277 --LKTSAKEPSAGAGEVLLSISYLPAANRLLVVLIKAKNLHSNQSKELLGKDVSVKVTLK 334
Query: 338 YGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLI 397
+ +++ KK+T K +NP++NE ++++P DLL S+E V+ D + ++ +G
Sbjct: 335 HQARKLKKKQTKRAKHKINPVWNEMIMFELPDDLLQASSVELEVLGQDDSGQSCALGHCS 394
Query: 398 LGAHSVTASGAEHWREVCESPRKPVAKWHSL 428
LG H+ + S HW E+ ++PR+ +A WH L
Sbjct: 395 LGLHT-SGSERSHWEEMLKNPRRQIAMWHQL 424
>gi|226342962 synaptotagmin XIV isoform 2 [Homo sapiens]
Length = 600
Score = 107 bits (267), Expect = 2e-23
Identities = 85/358 (23%), Positives = 160/358 (44%), Gaps = 36/358 (10%)
Query: 105 SRDKDPRGPSSGSCIDQLPIKMDYGEELRSPITSLTPGE--------SKTTSPSSPEEDV 156
S +K P S+G I+ K Y E++ S T++ E S+ P PE +
Sbjct: 246 SYNKCPSEGSTGHEIESFHNK-GYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEA 304
Query: 157 MLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLR 216
G+L + DY+ ++ L+VT+ +P + +T G+ + + +LP K+ R KT + R
Sbjct: 305 KYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYN-RTGGNSWQVHLVLLPIKKQRAKTSIQR 363
Query: 217 KTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGV-------- 268
PVF ETF F + + + + F + R ++ ++GE + L +
Sbjct: 364 GPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSL 422
Query: 269 ----DPS------TGKVQLTRDIIKRNIQKCISRG-----ELQVSLSYQPVAQRMTVVVL 313
+PS ++ ++ + C S E+ + L Y R++ V+
Sbjct: 423 PVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVI 482
Query: 314 KARHLPKMDITGLSGNPYVKVNVYYGR-KRIAKKKTHVKKCTLNPIFNESFIYDIPTDLL 372
K H + N YVK+ + + ++K KT +++ NP++ E+F++ + L
Sbjct: 483 KGSHFKNL-AANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQL 541
Query: 373 PDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSLSE 430
D+++ V + + E++G + LG +S HW E+ ES + V +WH+L E
Sbjct: 542 SDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 599
>gi|144226225 synaptotagmin XIV isoform 4 [Homo sapiens]
Length = 555
Score = 107 bits (267), Expect = 2e-23
Identities = 85/358 (23%), Positives = 160/358 (44%), Gaps = 36/358 (10%)
Query: 105 SRDKDPRGPSSGSCIDQLPIKMDYGEELRSPITSLTPGE--------SKTTSPSSPEEDV 156
S +K P S+G I+ K Y E++ S T++ E S+ P PE +
Sbjct: 201 SYNKCPSEGSTGHEIESFHNK-GYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEA 259
Query: 157 MLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRVLR 216
G+L + DY+ ++ L+VT+ +P + +T G+ + + +LP K+ R KT + R
Sbjct: 260 KYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYN-RTGGNSWQVHLVLLPIKKQRAKTSIQR 318
Query: 217 KTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGV-------- 268
PVF ETF F + + + + F + R ++ ++GE + L +
Sbjct: 319 GPC-PVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSL 377
Query: 269 ----DPS------TGKVQLTRDIIKRNIQKCISRG-----ELQVSLSYQPVAQRMTVVVL 313
+PS ++ ++ + C S E+ + L Y R++ V+
Sbjct: 378 PVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVI 437
Query: 314 KARHLPKMDITGLSGNPYVKVNVYYGR-KRIAKKKTHVKKCTLNPIFNESFIYDIPTDLL 372
K H + N YVK+ + + ++K KT +++ NP++ E+F++ + L
Sbjct: 438 KGSHFKNL-AANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQL 496
Query: 373 PDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSLSE 430
D+++ V + + E++G + LG +S HW E+ ES + V +WH+L E
Sbjct: 497 SDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLE 554
>gi|193804862 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 104 bits (259), Expect = 2e-22
Identities = 84/309 (27%), Positives = 145/309 (46%), Gaps = 53/309 (17%)
Query: 159 GSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDK--RHRVKTRVLR 216
G + FS+ Y ++LVV ++E H L D+ + S+PY+K +LPDK + + KT + R
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
Query: 217 KTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQ 276
T++P++DET Y IP S L L F V RF R+ +GE ++Q
Sbjct: 418 DTINPLYDETLR-YEIPESLLAQRTLQFSVWHHGRFGRNTFLGE------------AEIQ 464
Query: 277 LTRDIIKRNIQKCI----------------SRGELQVSLSYQPVAQ-------------- 306
+ + + + C+ +GEL VSL Y P ++
Sbjct: 465 MDSWKLDKKLDHCLPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGE 524
Query: 307 --RMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFI 364
+ V + +A++L G S + +VK + R + +K+KT V K TLNP +N +F+
Sbjct: 525 GGELQVWIKEAKNLTAAKAGGTS-DSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFV 583
Query: 365 YD-IPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASG-AEHWREVCESPRKPV 422
Y+ + + L + +E V D + N+ +G + LG + ++G W +S + V
Sbjct: 584 YNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDW---MDSTGEEV 640
Query: 423 AKWHSLSEY 431
+ W + +Y
Sbjct: 641 SLWQKMRQY 649
>gi|193804860 synaptotagmin-like 4 [Homo sapiens]
Length = 671
Score = 104 bits (259), Expect = 2e-22
Identities = 84/309 (27%), Positives = 145/309 (46%), Gaps = 53/309 (17%)
Query: 159 GSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDK--RHRVKTRVLR 216
G + FS+ Y ++LVV ++E H L D+ + S+PY+K +LPDK + + KT + R
Sbjct: 358 GRIAFSLKYEQQTQSLVVHVKECHQLAYADEAKKRSNPYVKTYLLPDKSRQGKRKTSIKR 417
Query: 217 KTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGKVQ 276
T++P++DET Y IP S L L F V RF R+ +GE ++Q
Sbjct: 418 DTINPLYDETLR-YEIPESLLAQRTLQFSVWHHGRFGRNTFLGE------------AEIQ 464
Query: 277 LTRDIIKRNIQKCI----------------SRGELQVSLSYQPVAQ-------------- 306
+ + + + C+ +GEL VSL Y P ++
Sbjct: 465 MDSWKLDKKLDHCLPLHGKISAESPTGLPSHKGELVVSLKYIPASKTPVGGDRKKSKGGE 524
Query: 307 --RMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFI 364
+ V + +A++L G S + +VK + R + +K+KT V K TLNP +N +F+
Sbjct: 525 GGELQVWIKEAKNLTAAKAGGTS-DSFVKGYLLPMRNKASKRKTPVMKKTLNPHYNHTFV 583
Query: 365 YD-IPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASG-AEHWREVCESPRKPV 422
Y+ + + L + +E V D + N+ +G + LG + ++G W +S + V
Sbjct: 584 YNGVRLEDLQHMCLELTVWDREPLASNDFLGGVRLGVGTGISNGEVVDW---MDSTGEEV 640
Query: 423 AKWHSLSEY 431
+ W + +Y
Sbjct: 641 SLWQKMRQY 649
>gi|239744413 PREDICTED: hypothetical protein LOC390213 [Homo
sapiens]
Length = 431
Score = 100 bits (250), Expect = 2e-21
Identities = 84/296 (28%), Positives = 140/296 (47%), Gaps = 27/296 (9%)
Query: 153 EEDVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILP--DKRHRV 210
++ LG+L F++ + AL T A GL + + +D Y+K +LP K ++
Sbjct: 134 DDSTALGTLEFTLLFEADNSALHCTAHRAKGLKPL--ASGSADAYVKANLLPGASKASQL 191
Query: 211 KTRVLRKTLDPVFDETFTFYGIPYSQLQ------DLVLHFLVL----SFDRFSRDDVIGE 260
+T +R T PV++ET T++G + DL H V R + +GE
Sbjct: 192 RTHTVRGTRVPVWEETLTYHGFTRQDAECKTLRSDLGGHQAVCVRGPMVQRQWQAPSLGE 251
Query: 261 VMVPLAGVDPSTGKVQLTRDII--KRNIQKCISR------GELQVSLSYQPVAQRMTVVV 312
+ VPL + P+ + + DI KR +++ + G + +SL Y + V V
Sbjct: 252 LRVPLRKLVPNRAR---SFDICLEKRRLEEVETEVAWEECGHVLLSLCYSSQQGGLLVGV 308
Query: 313 LKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLL 372
L+ HL MD G S +P+V++ ++ + +K KT V + TLNP FNE F Y P + L
Sbjct: 309 LRCAHLAPMDANGYS-DPFVRLFLHPNAGKKSKFKTSVHRKTLNPEFNEEFFYSGPREEL 367
Query: 373 PDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASGAEHWREVCESPRKPVAKWHSL 428
++ V D+D T ++ +G + LG+H+ + HW E + WH L
Sbjct: 368 AQKTLLVSVWDYDLGTADDFIGGVQLGSHA-SGERLRHWLECLGHSDHRLKLWHPL 422
>gi|31881667 synaptotagmin XV isoform b [Homo sapiens]
Length = 390
Score = 99.8 bits (247), Expect = 4e-21
Identities = 70/230 (30%), Positives = 119/230 (51%), Gaps = 8/230 (3%)
Query: 155 DVMLGSLTFSVDYNFPKKALVVTIQEAHGLPVMDDQTQGSDPYIKMTILPDKRHRVKTRV 214
D LG L FSV+Y + L+V + +A L ++ P +K+ +LPD+R ++++
Sbjct: 145 DGCLGRLWFSVEYEQEAERLLVGLIKAQHLQA---PSETCSPLVKLYLLPDERRFLQSKT 201
Query: 215 LRKTLDPVFDETFTFYGIPYSQLQDLVLHFLVLSFDRFSRDDVIGEVMVPLAGVDPSTGK 274
RKT +P FDE F F + + VL F V DR + ++G+V+ PL + G
Sbjct: 202 KRKTSNPQFDEHFIFQ-VSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKN-ETLVGD 259
Query: 275 VQ--LTRDIIKRNIQKCISRGELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYV 332
+ + RD+ +++ G+LQ LSY R+TVVVL+A+ L + G+ + +V
Sbjct: 260 CRRVIWRDLEAESLEPPSEFGDLQFCLSYNDYLSRLTVVVLRAKGLRLQEDRGIV-SVFV 318
Query: 333 KVNVYYGRKRIAKKKTHVKKCTLNPIFNESFIYDIPTDLLPDISIEFLVI 382
KV++ K + KKT ++NP++NE+F + L S+ V+
Sbjct: 319 KVSLMNHNKFVKCKKTSAVLGSINPVYNETFSFKADATELDTASLSLTVV 368
Score = 55.5 bits (132), Expect = 9e-08
Identities = 38/139 (27%), Positives = 72/139 (51%), Gaps = 8/139 (5%)
Query: 293 GELQVSLSYQPVAQRMTVVVLKARHLPKMDITGLSGNPYVKVNVYYGRKRIAKKKTHVKK 352
G L S+ Y+ A+R+ V ++KA+HL T +P VK+ + +R + KT K+
Sbjct: 149 GRLWFSVEYEQEAERLLVGLIKAQHLQAPSETC---SPLVKLYLLPDERRFLQSKT--KR 203
Query: 353 CTLNPIFNESFIYDIPTDLLPDISIEFLVIDFDRTTKNEVVGRLILGAHSVTASG---AE 409
T NP F+E FI+ + + + ++F V DR K++++G+++ + T G
Sbjct: 204 KTSNPQFDEHFIFQVSSKTITQRVLKFSVYHVDRQRKHQLLGQVLFPLKNETLVGDCRRV 263
Query: 410 HWREVCESPRKPVAKWHSL 428
WR++ +P +++ L
Sbjct: 264 IWRDLEAESLEPPSEFGDL 282
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.137 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,899,787
Number of Sequences: 37866
Number of extensions: 784770
Number of successful extensions: 2520
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 89
Number of HSP's successfully gapped in prelim test: 67
Number of HSP's that attempted gapping in prelim test: 1864
Number of HSP's gapped (non-prelim): 403
length of query: 431
length of database: 18,247,518
effective HSP length: 105
effective length of query: 326
effective length of database: 14,271,588
effective search space: 4652537688
effective search space used: 4652537688
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.