Guide to the Human Genome
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Name: MLKL Sequence: fasta or formatted (263aa) NCBI GI: 215820622
Description:

mixed lineage kinase domain-like isoform 2

Not currently referenced in the text

Other entries for this name:
alt prot {471aa} mixed lineage kinase domain-like isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.9         13           2
 C cysteine            2.7          7           1
 D aspartate           4.9         13           1
 E glutamate          10.3         27           2
 F phenylalanine       2.7          7           1
 G glycine             3.8         10           1
 H histidine           1.5          4           1
 I isoleucine          6.1         16           2
 K lysine             10.3         27           2
 L leucine            10.3         27           3
 M methionine          2.7          7           1
 N asparagine          3.8         10           1
 P proline             3.4          9           1
 Q glutamine           5.7         15           2
 R arginine            8.7         23           2
 S serine              9.5         25           3
 T threonine           2.7          7           2
 V valine              4.9         13           1
 W tryptophan          0.8          2           1
 Y tyrosine            0.4          1           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   mixed lineage kinase domain-like isoform 2 
MLKL                  0.677   mixed lineage kinase domain-like isoform 1 
KIF20B                0.024   M-phase phosphoprotein 1 
GOLGB1                0.024   golgi autoantigen, golgin subfamily b, macrogolgin ...
MYH2                  0.022   myosin, heavy chain 2, skeletal muscle, adult [Homo...
MYH2                  0.022   myosin, heavy chain 2, skeletal muscle, adult [Homo...
UPF2                  0.022   UPF2 regulator of nonsense transcripts homolog [Homo...
UPF2                  0.022   UPF2 regulator of nonsense transcripts homolog [Homo...
APOA1                 0.022   apolipoprotein A-I preproprotein 
KIAA1804              0.022   mixed lineage kinase 4 
OPTN                  0.020   optineurin 
OPTN                  0.020   optineurin 
OPTN                  0.020   optineurin 
OPTN                  0.020   optineurin 
PTK2                  0.020   PTK2 protein tyrosine kinase 2 isoform b 
PTK2                  0.020   PTK2 protein tyrosine kinase 2 isoform a 
RPGRIP1L              0.020   RPGRIP1-like isoform b 
RPGRIP1L              0.020   RPGRIP1-like isoform a 
LTK                   0.020   leukocyte receptor tyrosine kinase isoform 3 precur...
LTK                   0.020   leukocyte receptor tyrosine kinase isoform 1 precurs...
LTK                   0.020   leukocyte receptor tyrosine kinase isoform 2 precurs...
ROR1                  0.020   receptor tyrosine kinase-like orphan receptor 1 iso...
TNK2                  0.020   tyrosine kinase, non-receptor, 2 isoform 1 
TNK2                  0.020   tyrosine kinase, non-receptor, 2 isoform 2 
DDX46                 0.020   DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 
MAP3K9                0.020   mitogen-activated protein kinase kinase kinase 9 [Ho...
DSP                   0.018   desmoplakin isoform I 
KDM1                  0.018   amine oxidase (flavin containing) domain 2 isoform a...
MAP3K10               0.018   mitogen-activated protein kinase kinase kinase 10 [H...
KIAA1598              0.018   shootin1 isoform a 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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