Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 215820619
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|215820619 zinc finger protein 646 [Homo sapiens]
(1832 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|215820619 zinc finger protein 646 [Homo sapiens] 3885 0.0
gi|118600985 zinc finger protein 91 [Homo sapiens] 240 1e-62
gi|222418585 zinc finger protein 814 [Homo sapiens] 225 3e-58
gi|156627573 zinc finger protein 836 [Homo sapiens] 212 3e-54
gi|222831664 zinc finger protein 184 [Homo sapiens] 203 1e-51
gi|239747149 PREDICTED: hypothetical protein XP_002343926 isofor... 196 1e-49
gi|239747147 PREDICTED: hypothetical protein XP_002343925 isofor... 196 1e-49
gi|239747145 PREDICTED: hypothetical protein XP_002343927 isofor... 196 1e-49
gi|188497655 zinc finger protein 84 [Homo sapiens] 196 1e-49
gi|188497653 zinc finger protein 84 [Homo sapiens] 196 1e-49
gi|22095393 zinc finger protein 420 [Homo sapiens] 195 3e-49
gi|154800445 zinc finger protein 62 homolog [Homo sapiens] 190 1e-47
gi|122937229 zinc finger protein 629 [Homo sapiens] 188 4e-47
gi|6005976 zinc finger protein 208 [Homo sapiens] 186 2e-46
gi|153791350 replication initiator 1 isoform 1 [Homo sapiens] 184 7e-46
gi|153792539 replication initiator 1 isoform 1 [Homo sapiens] 184 7e-46
gi|153792647 replication initiator 1 isoform 3 [Homo sapiens] 184 7e-46
gi|153791994 replication initiator 1 isoform 1 [Homo sapiens] 184 7e-46
gi|34419633 zinc finger protein 135 [Homo sapiens] 178 5e-44
gi|68303809 zinc finger protein 43 [Homo sapiens] 177 6e-44
gi|154800449 zinc finger protein 132 [Homo sapiens] 173 2e-42
gi|52138523 zinc finger protein 418 [Homo sapiens] 172 3e-42
gi|122937213 zinc finger protein 99 [Homo sapiens] 172 4e-42
gi|24432013 zinc finger protein 668 [Homo sapiens] 172 4e-42
gi|74027276 zinc finger protein 226 isoform a [Homo sapiens] 171 5e-42
gi|74027274 zinc finger protein 226 isoform a [Homo sapiens] 171 5e-42
gi|209954795 zinc finger protein 761 [Homo sapiens] 164 1e-39
gi|55742736 zinc finger protein 700 [Homo sapiens] 163 1e-39
gi|209870092 hypothetical protein LOC345462 [Homo sapiens] 163 2e-39
gi|154091003 zinc finger protein 470 [Homo sapiens] 163 2e-39
>gi|215820619 zinc finger protein 646 [Homo sapiens]
Length = 1832
Score = 3885 bits (10074), Expect = 0.0
Identities = 1832/1832 (100%), Positives = 1832/1832 (100%)
Query: 1 MEDTPPSLSCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHP 60
MEDTPPSLSCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHP
Sbjct: 1 MEDTPPSLSCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHP 60
Query: 61 GSLVNHRRTHETGLFPCTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHLQGE 120
GSLVNHRRTHETGLFPCTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHLQGE
Sbjct: 61 GSLVNHRRTHETGLFPCTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHLQGE 120
Query: 121 TVSTDSWGQRLGSSEGWENQTKHTEETPDCESVPDPRAASGTWEDLPTRQREGLASHPGP 180
TVSTDSWGQRLGSSEGWENQTKHTEETPDCESVPDPRAASGTWEDLPTRQREGLASHPGP
Sbjct: 121 TVSTDSWGQRLGSSEGWENQTKHTEETPDCESVPDPRAASGTWEDLPTRQREGLASHPGP 180
Query: 181 EDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYK 240
EDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYK
Sbjct: 181 EDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYK 240
Query: 241 CSQCGKTYKHAGSLTNHRQSHTLGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCP 300
CSQCGKTYKHAGSLTNHRQSHTLGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCP
Sbjct: 241 CSQCGKTYKHAGSLTNHRQSHTLGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCP 300
Query: 301 RVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTS 360
RVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTS
Sbjct: 301 RVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTS 360
Query: 361 GELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTGVYPCSLCSKQLFNAAALKNHV 420
GELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTGVYPCSLCSKQLFNAAALKNHV
Sbjct: 361 GELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTGVYPCSLCSKQLFNAAALKNHV 420
Query: 421 RAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSL 480
RAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSL
Sbjct: 421 RAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSL 480
Query: 481 VNHRHSHRTGEYQCSLCPRKYPNLMALRNHVRVHCKAARRSADIGAEGAPSHLKVELPPD 540
VNHRHSHRTGEYQCSLCPRKYPNLMALRNHVRVHCKAARRSADIGAEGAPSHLKVELPPD
Sbjct: 481 VNHRHSHRTGEYQCSLCPRKYPNLMALRNHVRVHCKAARRSADIGAEGAPSHLKVELPPD 540
Query: 541 PVEAEAAPHTDQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAG 600
PVEAEAAPHTDQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAG
Sbjct: 541 PVEAEAAPHTDQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAG 600
Query: 601 EKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGDFSCGACAKHFHTMAAMK 660
EKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGDFSCGACAKHFHTMAAMK
Sbjct: 601 EKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGDFSCGACAKHFHTMAAMK 660
Query: 661 NHLRRHSRRRSRRHRKRAGGASGGREAKLLAAESWTRELEDNEGLESPQDPSGESPHGAE 720
NHLRRHSRRRSRRHRKRAGGASGGREAKLLAAESWTRELEDNEGLESPQDPSGESPHGAE
Sbjct: 661 NHLRRHSRRRSRRHRKRAGGASGGREAKLLAAESWTRELEDNEGLESPQDPSGESPHGAE 720
Query: 721 GNLESDGDCLQAESEGDKCGLERDETHFQGDKESGGTGEGLERKDASLLDNLDIPGEEGG 780
GNLESDGDCLQAESEGDKCGLERDETHFQGDKESGGTGEGLERKDASLLDNLDIPGEEGG
Sbjct: 721 GNLESDGDCLQAESEGDKCGLERDETHFQGDKESGGTGEGLERKDASLLDNLDIPGEEGG 780
Query: 781 GTHFCDSLTGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHTCSDCGHSFPHATGLLSHR 840
GTHFCDSLTGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHTCSDCGHSFPHATGLLSHR
Sbjct: 781 GTHFCDSLTGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHTCSDCGHSFPHATGLLSHR 840
Query: 841 PCHPPGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHR 900
PCHPPGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHR
Sbjct: 841 PCHPPGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHR 900
Query: 901 RQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSAGYGHIC 960
RQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSAGYGHIC
Sbjct: 901 RQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSAGYGHIC 960
Query: 961 GCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDIVNSVSGEGG 1020
GCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDIVNSVSGEGG
Sbjct: 961 GCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDIVNSVSGEGG 1020
Query: 1021 DAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGDFL 1080
DAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGDFL
Sbjct: 1021 DAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGDFL 1080
Query: 1081 CPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAAGSSELQVGPIPEGGSNKPQHMA 1140
CPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAAGSSELQVGPIPEGGSNKPQHMA
Sbjct: 1081 CPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAAGSSELQVGPIPEGGSNKPQHMA 1140
Query: 1141 EEGPGQAEVEKLQEELKVEPLEEVARVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSE 1200
EEGPGQAEVEKLQEELKVEPLEEVARVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSE
Sbjct: 1141 EEGPGQAEVEKLQEELKVEPLEEVARVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSE 1200
Query: 1201 RPFSCEVCGRSYKHAGSLINHRQSHQTGHFGCQACSKGFSNLMSLKNHRRIHADPRRFRC 1260
RPFSCEVCGRSYKHAGSLINHRQSHQTGHFGCQACSKGFSNLMSLKNHRRIHADPRRFRC
Sbjct: 1201 RPFSCEVCGRSYKHAGSLINHRQSHQTGHFGCQACSKGFSNLMSLKNHRRIHADPRRFRC 1260
Query: 1261 SECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRS 1320
SECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRS
Sbjct: 1261 SECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRS 1320
Query: 1321 HETGQYSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLE 1380
HETGQYSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLE
Sbjct: 1321 HETGQYSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLE 1380
Query: 1381 RHLREHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRPGERS 1440
RHLREHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRPGERS
Sbjct: 1381 RHLREHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRPGERS 1440
Query: 1441 QSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSPCHA 1500
QSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSPCHA
Sbjct: 1441 QSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSPCHA 1500
Query: 1501 GDCQLNGPTLSHMDSWDNRDNSSQLQPGSHSSCSQCGKTYCQSGSLLNHNTNKTDRHYCL 1560
GDCQLNGPTLSHMDSWDNRDNSSQLQPGSHSSCSQCGKTYCQSGSLLNHNTNKTDRHYCL
Sbjct: 1501 GDCQLNGPTLSHMDSWDNRDNSSQLQPGSHSSCSQCGKTYCQSGSLLNHNTNKTDRHYCL 1560
Query: 1561 LCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQVPAQMEE 1620
LCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQVPAQMEE
Sbjct: 1561 LCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQVPAQMEE 1620
Query: 1621 ARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVERARGGQAVTSMAAEDKERPFRCT 1680
ARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVERARGGQAVTSMAAEDKERPFRCT
Sbjct: 1621 ARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVERARGGQAVTSMAAEDKERPFRCT 1680
Query: 1681 QCGRSYRHAGSLLNHQKAHTTGLYPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKA 1740
QCGRSYRHAGSLLNHQKAHTTGLYPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKA
Sbjct: 1681 QCGRSYRHAGSLLNHQKAHTTGLYPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKA 1740
Query: 1741 FRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEEWTVAGSGAPVAPVT 1800
FRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEEWTVAGSGAPVAPVT
Sbjct: 1741 FRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEEWTVAGSGAPVAPVT 1800
Query: 1801 GRGDLPLPPPPTPTTPLLDPSPQWPADLSFSL 1832
GRGDLPLPPPPTPTTPLLDPSPQWPADLSFSL
Sbjct: 1801 GRGDLPLPPPPTPTTPLLDPSPQWPADLSFSL 1832
>gi|118600985 zinc finger protein 91 [Homo sapiens]
Length = 1191
Score = 240 bits (612), Expect = 1e-62
Identities = 251/1139 (22%), Positives = 440/1139 (38%), Gaps = 213/1139 (18%)
Query: 236 ERRYKCSQCGKTYKHAGSLTNHRQSHTLGI-YPCAICFKEFSNLMALKNHSRLHAQYRPY 294
E+ KC +C KT+ + +LTNH++ HT Y C C K F L L H + A+ + Y
Sbjct: 207 EKSCKCKECEKTFHWSSTLTNHKEIHTEDKPYKCEECGKAFKQLSTLTTHKIICAKEKIY 266
Query: 295 HCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGS 354
C C + F L H++ H GE+ + EE G ++ T L + ++
Sbjct: 267 KCEECGKAFLWSSTLTRHKRIHTGEKPY-KCEECGKAFSHSST-------LAKHKRIH-- 316
Query: 355 AELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTGV--YPCSLCSKQLFN 412
+GE +P++C +CG+ + + +L H++ H TG Y C C K N
Sbjct: 317 -----TGE---------KPYKCEECGKAFSRSSTLAKHKRIH-TGEKPYKCKECGKAFSN 361
Query: 413 AAALKNHVRAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGR 472
++ L NH H + + + L T HK + YKC ECG+
Sbjct: 362 SSTLANHKITHTEEKPYKCKECDKAFKRLSTL---TKHK-----IIHAGEKLYKCEECGK 413
Query: 473 AYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVH-------CKAARRSAD 523
A+ +L H+ H TGE Y+C C + + +L H R H CK + A
Sbjct: 414 AFNRSSNLTIHKFIH-TGEKPYKCEECGKAFNWSSSLTKHKRFHTREKPFKCKECGK-AF 471
Query: 524 IGAEGAPSHLKVELPPDPVEAEAAPHT--DQDHVCKHEEEATDITPAADKTAAHICSICG 581
I + H ++ P + E + KH+ T P + CG
Sbjct: 472 IWSSTLTRHKRIHTGEKPYKCEECGKAFRQSSTLTKHKIIHTGEKPYKFEE-------CG 524
Query: 582 LLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQT 641
F + +L +H + H S + + C++CGK+++ +L H+ H
Sbjct: 525 KAFRQSLTLNKHKIIH--------------SREKPYKCKECGKAFKQFSTLTTHKIIHAG 570
Query: 642 GD-FSCGACAKHFHTMAAMKNHLRRHSRRRSRRHRKRAGGASGGREAKLLAAESWTRELE 700
+ C C K F+ +++ H H+ +S + + A W+ L
Sbjct: 571 KKLYKCEECGKAFNHSSSLSTHKIIHTGEKSYKCEECG------------KAFLWSSTLR 618
Query: 701 DNEGLESPQDPSGESPHGAEGNLESDGDCLQAESEGDKCGLERDETHFQGDKESGGTGEG 760
++ + + GE P+ E +C +A S L + + G+K G
Sbjct: 619 RHKRIHT-----GEKPYKCE-------ECGKAFSHSS--ALAKHKRIHTGEKPYKCKECG 664
Query: 761 LERKDASLLDNLDIPGEEGGGTHFCDSLTGVDEDQKPATGQPNSSSHSANAVTGWQAGAA 820
++S L N I TH + E K + H AG
Sbjct: 665 KAFSNSSTLANHKI-------THTEEKPYKCKECDKTFKRLSTLTKHKII-----HAGEK 712
Query: 821 -HTCSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSA 878
+ C +CG +F ++ L H+ H Y+C C K F+ +L H + H T
Sbjct: 713 LYKCEECGKAFNRSSNLTIHKFIHTGEKPYKCEECGKAFNWSSSLTKHKRIH-----TRE 767
Query: 879 QPFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEA 938
+PF C CG F + H+R H+ + E A S L++
Sbjct: 768 KPFKCKECGKAFIWSSTLTRHKR-IHTGE----------KPYKCEECGKAFSRSSTLTKH 816
Query: 939 ELLNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGD 998
+ ++ ++ + C CG+ + +L +H + +G K G
Sbjct: 817 KTIHTGEKPYK----------CKECGKAFKHSSALAKH-KIIHAGEKLYKCEE----CGK 861
Query: 999 AMEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCG 1058
A + I+++ + +KS+E + S + + + + ++C +CG
Sbjct: 862 AFNQSSNLTTHKIIHT---KEKPSKSEECDKAFIWSSTLTE--HKRIHTREKTYKCEECG 916
Query: 1059 KTYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPE 1116
K + L H+++H TG+ + C C + + + H H
Sbjct: 917 KAFSQPSHLTTHKRMH-TGEKPYKCEECGKAFSQSSTLTTHKIIHT-------------- 961
Query: 1117 AAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKE--EVWEE 1174
KP E G + L E + E+ + +E + + +
Sbjct: 962 ----------------GEKPYKCEECGKAFRKSSTLTEHKIIHTGEKPYKCEECGKAFSQ 1005
Query: 1175 TTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGC 1232
++ R+ T EK P+ CE CG+++ + L H+ H TG + C
Sbjct: 1006 SSTLTRHT--RMHTGEK----------PYKCEECGKAFNRSSKLTTHKIIH-TGEKPYKC 1052
Query: 1233 QACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKA 1292
+ C K F + +L H+RIH + ++C ECGKAF L H+R+H
Sbjct: 1053 EECGKAFISSSTLNGHKRIHTREKPYKCEECGKAFSQSSTLTRHKRLH------------ 1100
Query: 1293 TREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHS 1349
++P++CG+CG+ ++ + +L H+ H TG+ Y C C K ++ L +H+++H+
Sbjct: 1101 -TGEKPYKCGECGKAFKESSALTKHKIIH-TGEKPYKCEKCGKAFNQSSILTNHKKIHT 1157
Score = 229 bits (585), Expect = 1e-59
Identities = 228/991 (23%), Positives = 375/991 (37%), Gaps = 150/991 (15%)
Query: 821 HTCSDCGHSFPHATGLLSHRP-CHPPGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQ 879
+ C +CG +F + L +H+ C IY+C C K F L H + H T +
Sbjct: 238 YKCEECGKAFKQLSTLTTHKIICAKEKIYKCEECGKAFLWSSTLTRHKRIH-----TGEK 292
Query: 880 PFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAE 939
P+ C CG F + H+R H+ + EE G A S +
Sbjct: 293 PYKCEECGKAFSHSSTLAKHKR-IHTGE-----KPYKCEECGKA-----------FSRSS 335
Query: 940 LLNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDA 999
L + +R + + + C CG+ + + +L H T ++ P A
Sbjct: 336 TLAKHKR----IHTGEKPYKCKECGKAFSNSSTLANHKI-----THTEEKPYKCKECDKA 386
Query: 1000 MEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGK 1059
+ + I+++ GE + G +L I + +P++C +CGK
Sbjct: 387 FKRLSTLTKHKIIHA--GEKLYKCEECGKAFNRSSNLTIH---KFIHTGEKPYKCEECGK 441
Query: 1060 TYRHGGSLVNHRKIH-QTGDFLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAA 1118
+ SL H++ H + F C C + + + H R H
Sbjct: 442 AFNWSSSLTKHKRFHTREKPFKCKECGKAFIWSSTLTRHKRIHT---------------- 485
Query: 1119 GSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKEEVWEETTVK 1178
KP E G + L + + E+ + +E
Sbjct: 486 --------------GEKPYKCEECGKAFRQSSTLTKHKIIHTGEKPYKFEE--------C 523
Query: 1179 GEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH-FGCQACSK 1237
G+ L + + S E+P+ C+ CG+++K +L H+ H + C+ C K
Sbjct: 524 GKAFRQSLTLNKH--KIIHSREKPYKCKECGKAFKQFSTLTTHKIIHAGKKLYKCEECGK 581
Query: 1238 GFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDR 1297
F++ SL H+ IH + ++C ECGKAF L H+R+H ++
Sbjct: 582 AFNHSSSLSTHKIIHTGEKSYKCEECGKAFLWSSTLRRHKRIHTG-------------EK 628
Query: 1298 PFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRR 1355
P++C +CG+ + H+ +L H+R H TG+ Y C C K +SN L +H+ H+E +
Sbjct: 629 PYKCEECGKAFSHSSALAKHKRIH-TGEKPYKCKECGKAFSNSSTLANHKITHTEEK--- 684
Query: 1356 AGRSRRTAVRCALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASEANLTGSQG 1415
+C C ++F +L +H H + G ++ NLT +
Sbjct: 685 -------PYKCKECDKTFKRLSTLTKHKIIHAGEKLYKCEECGKAFNRSS---NLTIHKF 734
Query: 1416 LETQLGGAEPVPHLEDGVPRPGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHS 1475
+ T G +P E G S + + + GKA W L H
Sbjct: 735 IHT---GEKPYKCEECGKAFNWSSSLTKHKRIHTREKPFKCKECGKAFIW--SSTLTRHK 789
Query: 1476 GGWVPQFLTRSEEPEDSVHRSPC-------HAGD----CQLNGPTLSHMDSWDNRDNSSQ 1524
+ + EE + RS H G+ C+ G H +
Sbjct: 790 RIHTGEKPYKCEECGKAFSRSSTLTKHKTIHTGEKPYKCKECGKAFKHSSALAKH---KI 846
Query: 1525 LQPGSHS-SCSQCGKTYCQSGSLLNHNTNKTDRHYCLL--CSKEFLNPVATKSHSHNHID 1581
+ G C +CGK + QS +L H T C K F+ H H
Sbjct: 847 IHAGEKLYKCEECGKAFNQSSNLTTHKIIHTKEKPSKSEECDKAFIWSSTLTEHKRIHTR 906
Query: 1582 AQTFACPDCGKAFESHQELASHLQAHARGHS-QVPAQMEE---ARDPKAGTGEDQVVLPG 1637
+T+ C +CGKAF SHL H R H+ + P + EE A + +++ G
Sbjct: 907 EKTYKCEECGKAFSQ----PSHLTTHKRMHTGEKPYKCEECGKAFSQSSTLTTHKIIHTG 962
Query: 1638 QGKAQEAPSETPRGPGESVERARGGQAVTS-MAAEDKERPFRCTQCGRSYRHAGSLLNHQ 1696
E P E + R +T E+P++C +CG+++ + +L H
Sbjct: 963 ---------EKPYKCEECGKAFRKSSTLTEHKIIHTGEKPYKCEECGKAFSQSSTLTRHT 1013
Query: 1697 KAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHA 1755
+ HT Y C C K L H HT K + C CGKAF +++ L GH R+H
Sbjct: 1014 RMHTGEKPYKCEECGKAFNRSSKLTTHKIIHTGEKPYKCEECGKAFISSSTLNGHKRIHT 1073
Query: 1756 PREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
RE P+ C C + F + + +H++ H E
Sbjct: 1074 -REKPYKCEECGKAFSQSSTLTRHKRLHTGE 1103
Score = 196 bits (499), Expect = 1e-49
Identities = 237/1131 (20%), Positives = 403/1131 (35%), Gaps = 249/1131 (22%)
Query: 4 TPPSLSCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSL 63
T S C +C++ F L+ H+E+ + +PY+C++CG+ ++ +L
Sbjct: 206 TEKSCKCKECEKTFHWSSTLTNHKEI------------HTEDKPYKCEECGKAFKQLSTL 253
Query: 64 VNHR-RTHETGLFPCTTCGKDFSNPMALKSHMRTHAPEGRRR---------HRPPRPKEA 113
H+ + ++ C CGK F L H R H E + H K
Sbjct: 254 TTHKIICAKEKIYKCEECGKAFLWSSTLTRHKRIHTGEKPYKCEECGKAFSHSSTLAKHK 313
Query: 114 TPHLQGETVSTDSWGQRLG-SSEGWENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQR 171
H + + G+ SS +++ HT E P C+ + S T
Sbjct: 314 RIHTGEKPYKCEECGKAFSRSSTLAKHKRIHTGEKPYKCKECGKAFSNSST--------- 364
Query: 172 EGLASHPGPEDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSP 231
LA+H T++ P L +++
Sbjct: 365 --LANH-----------KITHTEEKPYKCKECDKAFKRLSTLTKHKIIH----------- 400
Query: 232 PAEEERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQ 290
E+ YKC +CGK + + +LT H+ HT Y C C K F+ +L H R H +
Sbjct: 401 --AGEKLYKCEECGKAFNRSSNLTIHKFIHTGEKPYKCEECGKAFNWSSSLTKHKRFHTR 458
Query: 291 YRPYHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNG---------HTDESS 341
+P+ C C + F L H++ H GE+ + EE G HT E
Sbjct: 459 EKPFKCKECGKAFIWSSTLTRHKRIHTGEKPY-KCEECGKAFRQSSTLTKHKIIHTGEKP 517
Query: 342 QDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQ-TGV 400
+ S L+ + +P++C +CG+ ++ +L H+ H +
Sbjct: 518 YKFEECGKAFRQSLTLNKHKIIH----SREKPYKCKECGKAFKQFSTLTTHKIIHAGKKL 573
Query: 401 YPCSLCSKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTL 460
Y C C K ++++L H H GE L +T + + T
Sbjct: 574 YKCEECGKAFNHSSSLSTHKIIH------TGEKSYKCEECGKAFLWSSTLRRHKRIHT-- 625
Query: 461 DHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHCKAA 518
+PYKC ECG+A+ H +L H+ H TGE Y+C C + + N L NH H +
Sbjct: 626 GEKPYKCEECGKAFSHSSALAKHKRIH-TGEKPYKCKECGKAFSNSSTLANHKITHTE-- 682
Query: 519 RRSADIGAEGAPSHLKVELPPDPVEAEAAPHTDQDHVCKHEEEATDITPAADKTAAHICS 578
++ + CK
Sbjct: 683 --------------------------------EKPYKCKE-------------------- 690
Query: 579 ICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQT 638
C F+ +L +H + H AGEK + C +CGK++ S +L H+
Sbjct: 691 -CDKTFKRLSTLTKHKIIH-AGEK-------------LYKCEECGKAFNRSSNLTIHKFI 735
Query: 639 HQTGD--FSCGACAKHFHTMAAMKNHLRRHSRRRSRRHRKRAGGASGGREAKLLAAESWT 696
H TG+ + C C K F+ +++ H R H+R + + ++ A W+
Sbjct: 736 H-TGEKPYKCEECGKAFNWSSSLTKHKRIHTREKPFKCKECG------------KAFIWS 782
Query: 697 RELEDNEGLESPQDPSGESPHGAEGNLESDGDCLQAESEGDKCGLERDETHFQGDKESGG 756
L ++ + +GE P+ E +C +A S L + +T G+K
Sbjct: 783 STLTRHKRIH-----TGEKPYKCE-------ECGKAFSRSST--LTKHKTIHTGEKPYKC 828
Query: 757 TGEGLERKDASLLDNLDIPGEEGGGTHFCDSLTGVDEDQKPATGQPNSSSHSANAVTGWQ 816
G K +S L I H + L +E K N ++H
Sbjct: 829 KECGKAFKHSSALAKHKI-------IHAGEKLYKCEECGKAFNQSSNLTTHK-------- 873
Query: 817 AGAAHT------CSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQN 869
HT +C +F ++ L H+ H Y+C C K F L +H +
Sbjct: 874 --IIHTKEKPSKSEECDKAFIWSSTLTEHKRIHTREKTYKCEECGKAFSQPSHLTTHKRM 931
Query: 870 HRPGEATSAQPFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEE-GVAEAAPA 928
H T +P+ C CG F + SS+ T GE+ E A
Sbjct: 932 H-----TGEKPYKCEECGKAF------------SQSSTLTTHKIIHTGEKPYKCEECGKA 974
Query: 929 RSPPLQLSEAELLNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADK 988
L+E ++++ ++ + C CG+ + +L RH + + +
Sbjct: 975 FRKSSTLTEHKIIHTGEKPYK----------CEECGKAFSQSSTLTRHTRMHTG-----E 1019
Query: 989 APSPLGVAGDAMEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQ 1048
P G A I+++ G E G S + G + +
Sbjct: 1020 KPYKCEECGKAFNRSSKLTTHKIIHT----GEKPYKCEECGKAFISSSTL-NGHKRIHTR 1074
Query: 1049 PRPFRCNQCGKTYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNH 1097
+P++C +CGK + +L H+++H TG+ + C C + + +A H
Sbjct: 1075 EKPYKCEECGKAFSQSSTLTRHKRLH-TGEKPYKCGECGKAFKESSALTKH 1124
Score = 187 bits (474), Expect = 1e-46
Identities = 227/971 (23%), Positives = 368/971 (37%), Gaps = 177/971 (18%)
Query: 2 EDTPPSLSCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSI----------------P 45
ED P C +C + F L L+ H+ + EE
Sbjct: 234 EDKP--YKCEECGKAFKQLSTLTTHKIICAKEKIYKCEECGKAFLWSSTLTRHKRIHTGE 291
Query: 46 RPYRCQQCGRGYRHPGSLVNHRRTHETGLFP--CTTCGKDFSNPMALKSHMRTHAPEGRR 103
+PY+C++CG+ + H +L H+R H TG P C CGK FS L H R H E
Sbjct: 292 KPYKCEECGKAFSHSSTLAKHKRIH-TGEKPYKCEECGKAFSRSSTLAKHKRIHTGE--- 347
Query: 104 RHRPPRPKEATPHLQGETVSTDSWGQRLGSSEGWENQTKHTEETP-DCESVPDPRAASGT 162
+P + KE G+ S SS ++ HTEE P C +
Sbjct: 348 --KPYKCKEC-----GKAFS--------NSSTLANHKITHTEEKPYKC------KECDKA 386
Query: 163 WEDLPTRQREGLASHPGPEDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFT 222
++ L T + + + G + N R+ L I E F
Sbjct: 387 FKRLSTLTKHKIIHAGEKLYKCEECGKAFN--RSSNLTIHKFIHTGEKPYKCEECGKAFN 444
Query: 223 GGQEPTQSPPAE-EERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMA 280
T+ E+ +KC +CGK + + +LT H++ HT Y C C K F
Sbjct: 445 WSSSLTKHKRFHTREKPFKCKECGKAFIWSSTLTRHKRIHTGEKPYKCEECGKAFRQSST 504
Query: 281 LKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDES 340
L H +H +PY C + FR L +H+ H E+ + +E G T
Sbjct: 505 LTKHKIIHTGEKPYKFEECGKAFRQSLTLNKHKIIHSREKPY-KCKECGKAFKQFST--- 560
Query: 341 SQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG- 399
L + ++++ +L ++C +CG+ + H+ SL H+ H TG
Sbjct: 561 ----LTTHKIIHAGKKL----------------YKCEECGKAFNHSSSLSTHKIIH-TGE 599
Query: 400 -VYPCSLCSKQLFNAAALKNHVRAH--HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDP 456
Y C C K ++ L+ H R H +P + E G+ + L + H E
Sbjct: 600 KSYKCEECGKAFLWSSTLRRHKRIHTGEKPYK-CEECGKAFSHSSALAKHKRIHTGE--- 655
Query: 457 TTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE-YQCSLCPRKYPNLMALRNHVRVHC 515
+PYKC ECG+A+ + +L NH+ +H + Y+C C + + L L H +H
Sbjct: 656 ------KPYKCKECGKAFSNSSTLANHKITHTEEKPYKCKECDKTFKRLSTLTKHKIIHA 709
Query: 516 -----------KAARRSADIGAEGAPSHLKVELPPDPVEAE--AAPHTDQDHVCKHEEEA 562
KA RS+++ H + P + E + KH+
Sbjct: 710 GEKLYKCEECGKAFNRSSNL-----TIHKFIHTGEKPYKCEECGKAFNWSSSLTKHKRIH 764
Query: 563 TDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKEN---------------SRT 607
T P C CG F + +L RH H GEK ++
Sbjct: 765 TREKPFK-------CKECGKAFIWSSTLTRHKRIH-TGEKPYKCEECGKAFSRSSTLTKH 816
Query: 608 ETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRR 665
+T + + + C++CGK+++HS +L H+ H G+ + C C K F+ + + H
Sbjct: 817 KTIHTGEKPYKCKECGKAFKHSSALAKHKIIH-AGEKLYKCEECGKAFNQSSNLTTHKII 875
Query: 666 HSRR---RSRRHRKRAGGASGGREAKLLAAESWTRELED-NEGLESPQD-------PSGE 714
H++ +S K +S E K + T + E+ + P +GE
Sbjct: 876 HTKEKPSKSEECDKAFIWSSTLTEHKRIHTREKTYKCEECGKAFSQPSHLTTHKRMHTGE 935
Query: 715 SPHGAEGNLESDGDCLQAESEGDKCGLERDETHFQGDK--ESGGTGEGLERKDASLLDNL 772
P+ E +C +A S+ L + G+K + G+ RK ++L ++
Sbjct: 936 KPYKCE-------ECGKAFSQSST--LTTHKIIHTGEKPYKCEECGKAF-RKSSTLTEHK 985
Query: 773 DIPGEEGGGTHFCDSLTGVDEDQKPATGQPNSSSHSANAVTGWQAG-AAHTCSDCGHSFP 831
I G + C+ G+ S S + T G + C +CG +F
Sbjct: 986 II--HTGEKPYKCEE-----------CGKAFSQSSTLTRHTRMHTGEKPYKCEECGKAFN 1032
Query: 832 HATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIF 890
++ L +H+ H Y+C C K F S L H + H T +P+ C CG F
Sbjct: 1033 RSSKLTTHKIIHTGEKPYKCEECGKAFISSSTLNGHKRIH-----TREKPYKCEECGKAF 1087
Query: 891 PGRAGYRLHRR 901
+ H+R
Sbjct: 1088 SQSSTLTRHKR 1098
Score = 172 bits (435), Expect = 4e-42
Identities = 171/688 (24%), Positives = 267/688 (38%), Gaps = 136/688 (19%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C + F LS H+ ++H + Y+C++CG+ + +L H+R
Sbjct: 576 CEECGKAFNHSSSLSTHK-IIHTGE-----------KSYKCEECGKAFLWSSTLRRHKRI 623
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHLQGETVSTDSW 127
H TG P C CGK FS+ AL H R H E +P + KE G+ S
Sbjct: 624 H-TGEKPYKCEECGKAFSHSSALAKHKRIHTGE-----KPYKCKEC-----GKAFSN--- 669
Query: 128 GQRLGSSEGWENQTKHTEETP----DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDG 183
SS ++ HTEE P +C+ T++ L T + +
Sbjct: 670 -----SSTLANHKITHTEEKPYKCKECDK---------TFKRLSTLTKHKIIHAGEKLYK 715
Query: 184 ADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAE-EERRYKCS 242
+ G + N R+ L I E F T+ E+ +KC
Sbjct: 716 CEECGKAFN--RSSNLTIHKFIHTGEKPYKCEECGKAFNWSSSLTKHKRIHTREKPFKCK 773
Query: 243 QCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPR 301
+CGK + + +LT H++ HT Y C C K FS L H +H +PY C C +
Sbjct: 774 ECGKAFIWSSTLTRHKRIHTGEKPYKCEECGKAFSRSSTLTKHKTIHTGEKPYKCKECGK 833
Query: 302 VFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSG 361
F+ L +H+ H GE+ + EE G + N S+ L+T
Sbjct: 834 AFKHSSALAKHKIIHAGEKLY-KCEECG-------------------KAFNQSSNLTTHK 873
Query: 362 ELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSH-QTGVYPCSLCSKQLFNAAALKNHV 420
+ + +P + +C + + + +L H++ H + Y C C K + L H
Sbjct: 874 IIH----TKEKPSKSEECDKAFIWSSTLTEHKRIHTREKTYKCEECGKAFSQPSHLTTHK 929
Query: 421 RAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSL 480
R H + E + + L TTHK +PYKC ECG+A+R +L
Sbjct: 930 RMHTGEKPYKCEECGKAFSQSSTL---TTHK-----IIHTGEKPYKCEECGKAFRKSSTL 981
Query: 481 VNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHC-----------KAARRSADIGAE 527
H+ H TGE Y+C C + + L H R+H KA RS+ +
Sbjct: 982 TEHKIIH-TGEKPYKCEECGKAFSQSSTLTRHTRMHTGEKPYKCEECGKAFNRSSKL--- 1037
Query: 528 GAPSHLKVELPPDPVEAE------AAPHTDQDHVCKHEEEATDITPAADKTAAHICSICG 581
+H + P + E + T H H E + C CG
Sbjct: 1038 --TTHKIIHTGEKPYKCEECGKAFISSSTLNGHKRIHTRE-----------KPYKCEECG 1084
Query: 582 LLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQT 641
F + +L RH H GEK + C +CGK+++ S +L H+ H T
Sbjct: 1085 KAFSQSSTLTRHKRLH-TGEK-------------PYKCGECGKAFKESSALTKHKIIH-T 1129
Query: 642 GD--FSCGACAKHFHTMAAMKNHLRRHS 667
G+ + C C K F+ + + NH + H+
Sbjct: 1130 GEKPYKCEKCGKAFNQSSILTNHKKIHT 1157
Score = 163 bits (413), Expect = 1e-39
Identities = 218/1058 (20%), Positives = 383/1058 (36%), Gaps = 182/1058 (17%)
Query: 619 CRDCGKSYRHSGSLINHRQTH-QTGDFSCGACAKHFHTMAAMKNHLRRHSRRRSRRHRKR 677
C++C K++ S +L NH++ H + + C C K F ++ + H ++ + + +
Sbjct: 212 CKECEKTFHWSSTLTNHKEIHTEDKPYKCEECGKAFKQLSTLTTHKIICAKEKIYKCEEC 271
Query: 678 AGGASGGREAKLLAAESWTRELEDNEGLESPQDPSGESPHGAEGNLESDGDCLQAESEGD 737
A W+ L ++ + + GE P+ E +C +A S
Sbjct: 272 G------------KAFLWSSTLTRHKRIHT-----GEKPYKCE-------ECGKAFSHSS 307
Query: 738 KCGLERDETHFQGDK--ESGGTGEGLERKDASLLDNLDIPGEEGGGTHFCDSLTGVDEDQ 795
L + + G+K + G+ R GE+ C
Sbjct: 308 T--LAKHKRIHTGEKPYKCEECGKAFSRSSTLAKHKRIHTGEKPYKCKECGKAFS----- 360
Query: 796 KPATGQPNSSSHSANAVTGWQAGAAHTCSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCP 854
NSS+ + + +T + + C +C +F + L H+ H +Y+C C
Sbjct: 361 -------NSSTLANHKITHTEE-KPYKCKECDKAFKRLSTLTKHKIIHAGEKLYKCEECG 412
Query: 855 KEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSE 914
K F+ L H H T +P+ C CG F + H+R
Sbjct: 413 KAFNRSSNLTIHKFIH-----TGEKPYKCEECGKAFNWSSSLTKHKR------------- 454
Query: 915 EEGEEEGVAEAAPARSPPLQLSE---AELLNQLQREVEALDSAGYGHICGCCGQTYDDLG 971
R P + E A + + + + + + C CG+ +
Sbjct: 455 -----------FHTREKPFKCKECGKAFIWSSTLTRHKRIHTGEKPYKCEECGKAFRQSS 503
Query: 972 SLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDIVNSVSG-----EGGDAKSQE 1026
+L +H + + P G A + I++S E G A Q
Sbjct: 504 TLTKHKIIHTG-----EKPYKFEECGKAFRQSLTLNKHKIIHSREKPYKCKECGKAFKQF 558
Query: 1027 GAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGD--FLCPVC 1084
T ++ A + ++C +CGK + H SL H+ IH TG+ + C C
Sbjct: 559 STLTT----------HKIIHAGKKLYKCEECGKAFNHSSSLSTHKIIH-TGEKSYKCEEC 607
Query: 1085 SRCYPNLAAYRNHLRNHP-----RCKGSEPQVGPIPEAAGSSELQVGPIP----EGG--- 1132
+ + + R H R H +C+ A + G P E G
Sbjct: 608 GKAFLWSSTLRRHKRIHTGEKPYKCEECGKAFSHSSALAKHKRIHTGEKPYKCKECGKAF 667
Query: 1133 -------SNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKEEVWE-ETTVKGEEIEP 1184
++K H E+ E +K + L ++ E++++ E K
Sbjct: 668 SNSSTLANHKITHTEEKPYKCKECDKTFKRLSTLTKHKIIHAGEKLYKCEECGKAFNRSS 727
Query: 1185 RLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSH-QTGHFGCQACSKGFSNLM 1243
L T K T E+P+ CE CG+++ + SL H++ H + F C+ C K F
Sbjct: 728 NL-TIHKFIHT---GEKPYKCEECGKAFNWSSSLTKHKRIHTREKPFKCKECGKAFIWSS 783
Query: 1244 SLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQ 1303
+L H+RIH + ++C ECGKAF L H+ +H ++P++C +
Sbjct: 784 TLTRHKRIHTGEKPYKCEECGKAFSRSSTLTKHKTIH-------------TGEKPYKCKE 830
Query: 1304 CGRTYRHAGSLLNHRRSHETGQ-YSCPTCPKTYSNRMALKDHQRLHSENRRRRAG----- 1357
CG+ ++H+ +L H+ H + Y C C K ++ L H+ +H++ + ++
Sbjct: 831 CGKAFKHSSALAKHKIIHAGEKLYKCEECGKAFNQSSNLTTHKIIHTKEKPSKSEECDKA 890
Query: 1358 -------------RSRRTAVRCALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGTA 1404
+R +C CG++F L H R H T +P + G A
Sbjct: 891 FIWSSTLTEHKRIHTREKTYKCEECGKAFSQPSHLTTHKRMH--TGEKPYKCEE--CGKA 946
Query: 1405 ASEAN-LTGSQGLETQLGGAEPVPHLEDGVPRPGERSQSPIRAASSEAPEPLSWGAGKAG 1463
S+++ LT + + T G +P E G + + + + GKA
Sbjct: 947 FSQSSTLTTHKIIHT---GEKPYKCEECGKAFRKSSTLTEHKIIHTGEKPYKCEECGKA- 1002
Query: 1464 GWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSP-------CHAGD----CQLNGPTLSH 1512
+ L H+ + + EE + +RS H G+ C+ G
Sbjct: 1003 -FSQSSTLTRHTRMHTGEKPYKCEECGKAFNRSSKLTTHKIIHTGEKPYKCEECGKAFIS 1061
Query: 1513 MDSWDNRDN-SSQLQPGSHSSCSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNP 1569
+ + ++ +P C GK + QS +L H T + C C K F
Sbjct: 1062 SSTLNGHKRIHTREKPYKCEEC---GKAFSQSSTLTRHKRLHTGEKPYKCGECGKAFKES 1118
Query: 1570 VATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAH 1607
A H H + + C CGKAF L +H + H
Sbjct: 1119 SALTKHKIIHTGEKPYKCEKCGKAFNQSSILTNHKKIH 1156
Score = 159 bits (401), Expect = 3e-38
Identities = 163/726 (22%), Positives = 264/726 (36%), Gaps = 138/726 (19%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C + F L++H+ ++H +PY+ ++CG+ +R +L H+
Sbjct: 492 CEECGKAFRQSSTLTKHK-IIHTGE-----------KPYKFEECGKAFRQSLTLNKHKII 539
Query: 70 HETGL-FPCTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHLQG--------- 119
H + C CGK F L +H HA G++ ++ +A H
Sbjct: 540 HSREKPYKCKECGKAFKQFSTLTTHKIIHA--GKKLYKCEECGKAFNHSSSLSTHKIIHT 597
Query: 120 --ETVSTDSWGQR-LGSSEGWENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQREGLA 175
++ + G+ L SS ++ HT E P CE + S LA
Sbjct: 598 GEKSYKCEECGKAFLWSSTLRRHKRIHTGEKPYKCEECGKAFSHSSA-----------LA 646
Query: 176 SHPGPEDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEE 235
H G P + LA + T E
Sbjct: 647 KHKRIHTGEK------------PYKCKECGKAFSNSSTLANHKITHT------------E 682
Query: 236 ERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPY 294
E+ YKC +C KT+K +LT H+ H +Y C C K F+ L H +H +PY
Sbjct: 683 EKPYKCKECDKTFKRLSTLTKHKIIHAGEKLYKCEECGKAFNRSSNLTIHKFIHTGEKPY 742
Query: 295 HCPHCPRVFRLPRELLEHQQSHEGER--------QEPRWEEKGMPTTNGHTDESSQDQLP 346
C C + F L +H++ H E+ + W HT E
Sbjct: 743 KCEECGKAFNWSSSLTKHKRIHTREKPFKCKECGKAFIWSSTLTRHKRIHTGEKPYKCEE 802
Query: 347 SAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQ-TGVYPCSL 405
+ + S+ L+ + +P++C +CG+ ++H+ +L H+ H +Y C
Sbjct: 803 CGKAFSRSSTLTKHKTIHTG----EKPYKCKECGKAFKHSSALAKHKIIHAGEKLYKCEE 858
Query: 406 CSKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPY 465
C K ++ L H H + + E + + L T HK T Y
Sbjct: 859 CGKAFNQSSNLTTHKIIHTKEKPSKSEECDKAFIWSSTL---TEHKRIHTREKT-----Y 910
Query: 466 KCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHC-------- 515
KC ECG+A+ L H+ H TGE Y+C C + + L H +H
Sbjct: 911 KCEECGKAFSQPSHLTTHKRMH-TGEKPYKCEECGKAFSQSSTLTTHKIIHTGEKPYKCE 969
Query: 516 ---KAARRSADIGAEGAPSHLKVELPPDPVEAE--AAPHTDQDHVCKHEEEATDITPAAD 570
KA R+S+ + H + P + E + + +H T P
Sbjct: 970 ECGKAFRKSSTL-----TEHKIIHTGEKPYKCEECGKAFSQSSTLTRHTRMHTGEKP--- 1021
Query: 571 KTAAHICSICGLLFEDAESLERHGLTHGAGEKE------------------NSRTETTMS 612
+ C CG F + L H + H GEK + R T
Sbjct: 1022 ----YKCEECGKAFNRSSKLTTHKIIH-TGEKPYKCEECGKAFISSSTLNGHKRIHTREK 1076
Query: 613 PPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHSRRR 670
P + C +CGK++ S +L H++ H TG+ + CG C K F +A+ H H+ +
Sbjct: 1077 P---YKCEECGKAFSQSSTLTRHKRLH-TGEKPYKCGECGKAFKESSALTKHKIIHTGEK 1132
Query: 671 SRRHRK 676
+ K
Sbjct: 1133 PYKCEK 1138
Score = 149 bits (375), Expect = 3e-35
Identities = 130/606 (21%), Positives = 230/606 (37%), Gaps = 77/606 (12%)
Query: 1208 CGRSYKHAGSLINHRQSHQTGHFG-----CQACSKGFSNLMSLKNHRRIHADPRRFRCSE 1262
CG+ K +N + H H G C+ C K F + H+ ++ + +C E
Sbjct: 156 CGKYLKVFYKFLNSNR-HTIRHTGKKCFKCKKCVKSFCIRLHKTQHKCVYITEKSCKCKE 214
Query: 1263 CGKAFRLRKQLASHQRVHMERR-------GGGGTRKAT--------REDRPFRCGQCGRT 1307
C K F L +H+ +H E + G + +T +++ ++C +CG+
Sbjct: 215 CEKTFHWSSTLTNHKEIHTEDKPYKCEECGKAFKQLSTLTTHKIICAKEKIYKCEECGKA 274
Query: 1308 YRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVR 1365
+ + +L H+R H TG+ Y C C K +S+ L H+R+H+ + +
Sbjct: 275 FLWSSTLTRHKRIH-TGEKPYKCEECGKAFSHSSTLAKHKRIHTGEK----------PYK 323
Query: 1366 CALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEP 1425
C CG++F +L +H R H + G +++ AN
Sbjct: 324 CEECGKAFSRSSTLAKHKRIHTGEKPYKCKECGKAFSNSSTLAN--------------HK 369
Query: 1426 VPHLEDGVPRPGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTR 1485
+ H E+ + E ++ R ++ + + G G S + +F+
Sbjct: 370 ITHTEEKPYKCKECDKAFKRLSTLTKHKIIHAGEKLYKCEECGKAFNRSSNLTIHKFIHT 429
Query: 1486 SEEPEDSVHRSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHSSCSQCGKTYCQSGS 1545
E+P C+ G + S + C +CGK + S +
Sbjct: 430 GEKPY-----------KCEECGKAFNWSSSLTKHKRFHTRE--KPFKCKECGKAFIWSST 476
Query: 1546 LLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASH 1603
L H T + C C K F H H + + +CGKAF L H
Sbjct: 477 LTRHKRIHTGEKPYKCEECGKAFRQSSTLTKHKIIHTGEKPYKFEECGKAFRQSLTLNKH 536
Query: 1604 LQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQG--KAQEAPSETPRGPGESVERARG 1661
H+R + +A + +++ G+ K +E G++ +
Sbjct: 537 KIIHSREKPYKCKECGKAFKQFSTLTTHKIIHAGKKLYKCEEC--------GKAFNHS-- 586
Query: 1662 GQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLCPKLLPNLLSLK 1720
T E+ ++C +CG+++ + +L H++ HT Y C C K + +L
Sbjct: 587 SSLSTHKIIHTGEKSYKCEECGKAFLWSSTLRRHKRIHTGEKPYKCEECGKAFSHSSALA 646
Query: 1721 NHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQ 1780
H R HT K + C CGKAF ++ L H H E P+ C C + F+R + +H+
Sbjct: 647 KHKRIHTGEKPYKCKECGKAFSNSSTLANHKITHT-EEKPYKCKECDKTFKRLSTLTKHK 705
Query: 1781 QQHQEE 1786
H E
Sbjct: 706 IIHAGE 711
Score = 146 bits (368), Expect = 2e-34
Identities = 159/684 (23%), Positives = 261/684 (38%), Gaps = 88/684 (12%)
Query: 1134 NKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKEEVWEETTVKGEEIEPRLETAEK-- 1191
+KP + G+ Q E+ EP ++ W E +++ + L EK
Sbjct: 57 SKPDLITYLEQGKEPWNMKQHEMVDEPTGICPHFPQDFWPEQSMEDSFQKVLLRKYEKCG 116
Query: 1192 --GCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGHFGCQACSKGFSNLMSLKNHR 1249
Q + C+V Y + QS F C K F ++ H
Sbjct: 117 HENLQLRKGCKSVDECKVHKEGYNKLNQCLTTAQSKV---FQCGKYLKVFYKFLNSNRHT 173
Query: 1250 RIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYR 1309
H + F+C +C K+F +R H+ V++ ++ +C +C +T+
Sbjct: 174 IRHTGKKCFKCKKCVKSFCIRLHKTQHKCVYI-------------TEKSCKCKECEKTFH 220
Query: 1310 HAGSLLNHRRSH-ETGQYSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCAL 1368
+ +L NH+ H E Y C C K + L H+ + ++ + +C
Sbjct: 221 WSSTLTNHKEIHTEDKPYKCEECGKAFKQLSTLTTHKIICAKEK----------IYKCEE 270
Query: 1369 CGRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASEAN-LTGSQGLETQLGGAEPVP 1427
CG++F +L RH R H T +P + G A S ++ L + + T G +P
Sbjct: 271 CGKAFLWSSTLTRHKRIH--TGEKPYKCEE--CGKAFSHSSTLAKHKRIHT---GEKPYK 323
Query: 1428 HLEDGVPRPGERSQSPI---RAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLT 1484
E G + RS + R + E P GKA + L NH +
Sbjct: 324 CEECG--KAFSRSSTLAKHKRIHTGEKPYKCK-ECGKA--FSNSSTLANHKITHTEEKPY 378
Query: 1485 RSEEPEDSVHR-------SPCHAGD----CQLNGPTLSHMDSWDNRDNSSQLQPGSHS-- 1531
+ +E + + R HAG+ C+ G NR ++ + H+
Sbjct: 379 KCKECDKAFKRLSTLTKHKIIHAGEKLYKCEECGKAF-------NRSSNLTIHKFIHTGE 431
Query: 1532 ---SCSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFA 1586
C +CGK + S SL H T C C K F+ H H + +
Sbjct: 432 KPYKCEECGKAFNWSSSLTKHKRFHTREKPFKCKECGKAFIWSSTLTRHKRIHTGEKPYK 491
Query: 1587 CPDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGK---AQE 1643
C +CGKAF L H H + P + EE G Q + + K ++E
Sbjct: 492 CEECGKAFRQSSTLTKHKIIHT---GEKPYKFEE-----CGKAFRQSLTLNKHKIIHSRE 543
Query: 1644 APSETPRGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TG 1702
P + + G++ ++ T ++ ++C +CG+++ H+ SL H+ HT
Sbjct: 544 KPYKC-KECGKAFKQF--STLTTHKIIHAGKKLYKCEECGKAFNHSSSLSTHKIIHTGEK 600
Query: 1703 LYPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFT 1762
Y C C K +L+ H R HT K + C CGKAF ++ L H R+H E P+
Sbjct: 601 SYKCEECGKAFLWSSTLRRHKRIHTGEKPYKCEECGKAFSHSSALAKHKRIHT-GEKPYK 659
Query: 1763 CPHCPRHFRRRISFVQHQQQHQEE 1786
C C + F + H+ H EE
Sbjct: 660 CKECGKAFSNSSTLANHKITHTEE 683
Score = 75.9 bits (185), Expect = 3e-13
Identities = 54/198 (27%), Positives = 78/198 (39%), Gaps = 39/198 (19%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C +CGK + QS +L H T + C C K F +H H + + C +C
Sbjct: 996 CEECGKAFSQSSTLTRHTRMHTGEKPYKCEECGKAFNRSSKLTTHKIIHTGEKPYKCEEC 1055
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPR 1650
GKAF S L H + H R + P + EE GKA S R
Sbjct: 1056 GKAFISSSTLNGHKRIHTR---EKPYKCEEC-----------------GKAFSQSSTLTR 1095
Query: 1651 GPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLC 1709
+R G E+P++C +CG++++ + +L H+ HT Y C C
Sbjct: 1096 H-----KRLHTG-----------EKPYKCGECGKAFKESSALTKHKIIHTGEKPYKCEKC 1139
Query: 1710 PKLLPNLLSLKNHSRTHT 1727
K L NH + HT
Sbjct: 1140 GKAFNQSSILTNHKKIHT 1157
Score = 64.7 bits (156), Expect = 8e-10
Identities = 65/267 (24%), Positives = 99/267 (37%), Gaps = 61/267 (22%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C + F L+ H+ ++H +PY+C++CG+ +R +L H+
Sbjct: 940 CEECGKAFSQSSTLTTHK-IIHTGE-----------KPYKCEECGKAFRKSSTLTEHKII 987
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPE--------GRRRHRPPR-PKEATPHLQ 118
H TG P C CGK FS L H R H E G+ +R + H
Sbjct: 988 H-TGEKPYKCEECGKAFSQSSTLTRHTRMHTGEKPYKCEECGKAFNRSSKLTTHKIIHTG 1046
Query: 119 GETVSTDSWGQRLGSSEGWENQTK-HTEETP-DCESVPDPRAASGTWEDLPTRQREGLAS 176
+ + G+ SS + HT E P CE + S T TR +
Sbjct: 1047 EKPYKCEECGKAFISSSTLNGHKRIHTREKPYKCEECGKAFSQSSTL----TRHKRLHTG 1102
Query: 177 HPGPEDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEE 236
+ G G +SA L + + TG E
Sbjct: 1103 EKPYKCGECGKAFKESSA-------------------LTKHKIIHTG------------E 1131
Query: 237 RRYKCSQCGKTYKHAGSLTNHRQSHTL 263
+ YKC +CGK + + LTNH++ HT+
Sbjct: 1132 KPYKCEKCGKAFNQSSILTNHKKIHTI 1158
>gi|222418585 zinc finger protein 814 [Homo sapiens]
Length = 855
Score = 225 bits (574), Expect = 3e-58
Identities = 173/617 (28%), Positives = 263/617 (42%), Gaps = 116/617 (18%)
Query: 1198 SSERPFSCEVCGRSYKHAGSLINHRQSH-QTGHFGCQACSKGFSNLMSLKNHRRIHADPR 1256
+ +RP+ C CG+S+ S NH++ H + H+ C C K FS +S NH+R+H R
Sbjct: 319 TGKRPYECGECGKSFSKYASFSNHQRVHTEKKHYECGECGKSFSKYVSFSNHQRVHTGKR 378
Query: 1257 RFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLN 1316
+ C ECGK+F ++HQRVH +++ + CG+CG+++ SL+
Sbjct: 379 PYECGECGKSFSKYASFSNHQRVHTDKKH-------------YECGECGKSFSQKSSLIQ 425
Query: 1317 HRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRS------RRTAV---- 1364
H+R H TG+ Y C C K++S+ L+ HQR+H+ R + G +R+ V
Sbjct: 426 HQRFH-TGEKPYGCEECGKSFSSEGHLRSHQRVHAGERPFKCGECVKSFSHKRSLVHHQR 484
Query: 1365 --------RCALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASEANLTGSQGL 1416
+C CG+SF +G+L H R H T P G + +S+ +L Q +
Sbjct: 485 VHSGERPYQCGECGKSFSQKGNLVLHQRVH--TGARPYEC-GECGKSFSSKGHLRNHQQI 541
Query: 1417 ETQLGGAEPVPHLEDGVPRPGERSQS-----PIRAASSEAPEPLSWGAGKAG-GWPVGGG 1470
H D + GE +S + P S+G G+ G + G
Sbjct: 542 -----------HTGDRLYECGECGKSFSHKGTLILHQRVHPRERSYGCGECGKSFSSIGH 590
Query: 1471 LGNHSGGWVPQFLTRSEEPEDSVHRSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGSH 1530
L +H Q + E P + G+C G + SH S + ++ G
Sbjct: 591 LRSH------QRVHTGERPYE--------CGEC---GKSFSHKRSLVHHQ---RMHTGER 630
Query: 1531 S-SCSQCGKTYCQSGSLLNHN-TNKTDRHY-CLLCSKEFLNPVATKSHSHNHIDAQTFAC 1587
C CGK++ + G L NH + T+R + C C K F + H H H + + C
Sbjct: 631 PYKCGDCGKSFNEKGHLRNHQRVHTTERPFKCGECGKCFSHKGNLILHQHGHTGERPYVC 690
Query: 1588 PDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSE 1647
+CGK F+ SHL H R H+ GE A EA +
Sbjct: 691 RECGKLFKKK----SHLLVHQRIHN----------------GEKPY-------ACEACQK 723
Query: 1648 TPRGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPC 1706
R + + R ERP+ C CG+S+ H+ + H++ HT Y C
Sbjct: 724 FFRNKYQLIAHQR---------VHTGERPYECNDCGKSFTHSSTFCVHKRIHTGEKPYEC 774
Query: 1707 SLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHC 1766
S C K S H R HT K + CS CGK+F ++ L H RVH E P+ C C
Sbjct: 775 SECGKSFAESSSFTKHKRVHTGEKPYECSECGKSFAESSSLTKHKRVHT-GEKPYKCEKC 833
Query: 1767 PRHFRRRISFVQHQQQH 1783
+ F ++ + HQ H
Sbjct: 834 GKLFNKKSHLLVHQSSH 850
Score = 213 bits (542), Expect = 1e-54
Identities = 162/599 (27%), Positives = 248/599 (41%), Gaps = 77/599 (12%)
Query: 1199 SERPFSCEVCGRSYKHAGSLINHRQSHQTGHFGCQACSKGFSNLMSLKNHRRIHADPRRF 1258
+E+ C CG+S+ S NH++ H C C K FS +S NH+R+H R +
Sbjct: 265 TEKKHECGECGKSFSKYVSFSNHQRVHTEKKHECGECGKSFSKYVSFSNHQRVHTGKRPY 324
Query: 1259 RCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHR 1318
C ECGK+F ++HQRVH E++ + CG+CG+++ S NH+
Sbjct: 325 ECGECGKSFSKYASFSNHQRVHTEKKH-------------YECGECGKSFSKYVSFSNHQ 371
Query: 1319 RSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGR 1376
R H TG+ Y C C K++S + +HQR+H++ + C CG+SF +
Sbjct: 372 RVH-TGKRPYECGECGKSFSKYASFSNHQRVHTDKKH----------YECGECGKSFSQK 420
Query: 1377 GSLERHLREHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRP 1436
SL +H R H E G + +SE +L Q + G P E
Sbjct: 421 SSLIQHQRFHTG---EKPYGCEECGKSFSSEGHLRSHQRVHA---GERPFKCGECVKSFS 474
Query: 1437 GERSQ-SPIRAASSEAPEPLSWGAGKAG-GWPVGGGLGNHSGGWVPQFLTRSEEPEDSVH 1494
+RS R S E P + G+ G + G L H VH
Sbjct: 475 HKRSLVHHQRVHSGERP----YQCGECGKSFSQKGNLVLHQ----------------RVH 514
Query: 1495 RS--PCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHS-SCSQCGKTYCQSGSLLNHN- 1550
P G+C + + H+ N Q+ G C +CGK++ G+L+ H
Sbjct: 515 TGARPYECGECGKSFSSKGHLR------NHQQIHTGDRLYECGECGKSFSHKGTLILHQR 568
Query: 1551 TNKTDRHY-CLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHAR 1609
+ +R Y C C K F + +SH H + + C +CGK+F + L H + H
Sbjct: 569 VHPRERSYGCGECGKSFSSIGHLRSHQRVHTGERPYECGECGKSFSHKRSLVHHQRMHTG 628
Query: 1610 GHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVER-ARGGQAVTSM 1668
++ + K Q V +E P GE + + G +
Sbjct: 629 ERPYKCGDCGKSFNEKGHLRNHQRV---------HTTERPFKCGECGKCFSHKGNLILHQ 679
Query: 1669 AAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHT 1727
ERP+ C +CG+ ++ LL HQ+ H Y C C K N L H R HT
Sbjct: 680 HGHTGERPYVCRECGKLFKKKSHLLVHQRIHNGEKPYACEACQKFFRNKYQLIAHQRVHT 739
Query: 1728 DPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
+ + C+ CGK+F ++ H R+H E P+ C C + F SF +H++ H E
Sbjct: 740 GERPYECNDCGKSFTHSSTFCVHKRIHT-GEKPYECSECGKSFAESSSFTKHKRVHTGE 797
Score = 195 bits (496), Expect = 3e-49
Identities = 180/703 (25%), Positives = 280/703 (39%), Gaps = 126/703 (17%)
Query: 1054 CNQCGKTYRHGGSLVNHRKIHQTGDFLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGP 1113
C +CGK++ SL NH+++H C C + + ++ NH R H K + G
Sbjct: 244 CCECGKSFSKYASLSNHQRVHTEKKHECGECGKSFSKYVSFSNHQRVHTEKKHECGECGK 303
Query: 1114 ----IPEAAGSSELQVGPIP----EGGSNKPQHMAEEGPGQAEVEKLQEELKV--EPLEE 1163
+ + G P E G + ++ + + EK E + +
Sbjct: 304 SFSKYVSFSNHQRVHTGKRPYECGECGKSFSKYASFSNHQRVHTEKKHYECGECGKSFSK 363
Query: 1164 VARVKEEVWEETTVKGEEIEPRLETAEKGC-----QTEASSERPFSCEVCGRSYKHAGSL 1218
T + E ++ K Q + ++ + C CG+S+ SL
Sbjct: 364 YVSFSNHQRVHTGKRPYECGECGKSFSKYASFSNHQRVHTDKKHYECGECGKSFSQKSSL 423
Query: 1219 INHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASH 1276
I H++ H TG +GC+ C K FS+ L++H+R+HA R F+C EC K+F ++ L H
Sbjct: 424 IQHQRFH-TGEKPYGCEECGKSFSSEGHLRSHQRVHAGERPFKCGECVKSFSHKRSLVHH 482
Query: 1277 QRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ-YSCPTCPKTY 1335
QRVH +RP++CG+CG+++ G+L+ H+R H + Y C C K++
Sbjct: 483 QRVH-------------SGERPYQCGECGKSFSQKGNLVLHQRVHTGARPYECGECGKSF 529
Query: 1336 SNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHEETEREPAN 1395
S++ L++HQ++H+ +R C CG+SF +G+L H R H RE +
Sbjct: 530 SSKGHLRNHQQIHTGDR----------LYECGECGKSFSHKGTLILHQRVH---PRERSY 576
Query: 1396 GQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRPGERS-QSPIRAASSEAPEP 1454
G G + +S +L Q + T G P E G +RS R + E P
Sbjct: 577 GCGECGKSFSSIGHLRSHQRVHT---GERPYECGECGKSFSHKRSLVHHQRMHTGERP-- 631
Query: 1455 LSWGAGKAG-GWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRS--PCHAGDCQLNGPTLS 1511
+ G G + G L NH VH + P G+C G S
Sbjct: 632 --YKCGDCGKSFNEKGHLRNH----------------QRVHTTERPFKCGEC---GKCFS 670
Query: 1512 HMDSWDNRDNSSQLQPGSHSS----CSQCGKTYCQSGSLLNHNT--NKTDRHYCLLCSKE 1565
H + N Q G C +CGK + + LL H N + C C K
Sbjct: 671 H------KGNLILHQHGHTGERPYVCRECGKLFKKKSHLLVHQRIHNGEKPYACEACQKF 724
Query: 1566 FLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPK 1625
F N +H H + + C DCGK+F H + H
Sbjct: 725 FRNKYQLIAHQRVHTGERPYECNDCGKSFTHSSTFCVHKRIH------------------ 766
Query: 1626 AGTGEDQVVLPGQGKA-QEAPSETPRGPGESVERARGGQAVTSMAAEDKERPFRCTQCGR 1684
TGE GK+ E+ S T +R G E+P+ C++CG+
Sbjct: 767 --TGEKPYECSECGKSFAESSSFTKH------KRVHTG-----------EKPYECSECGK 807
Query: 1685 SYRHAGSLLNHQKAHT-TGLYPCSLCPKLLPNLLSLKNHSRTH 1726
S+ + SL H++ HT Y C C KL L H +H
Sbjct: 808 SFAESSSLTKHKRVHTGEKPYKCEKCGKLFNKKSHLLVHQSSH 850
Score = 193 bits (491), Expect = 1e-48
Identities = 173/677 (25%), Positives = 264/677 (38%), Gaps = 138/677 (20%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C + F S H+ + + RPY C +CG+ + S NH+R
Sbjct: 298 CGECGKSFSKYVSFSNHQRV------------HTGKRPYECGECGKSFSKYASFSNHQRV 345
Query: 70 H-ETGLFPCTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHLQGETVSTDSWG 128
H E + C CGK FS ++ +H R H G+R P+ GE + S
Sbjct: 346 HTEKKHYECGECGKSFSKYVSFSNHQRVHT--GKR-----------PYECGECGKSFSKY 392
Query: 129 QRLGSSEGWENQTKHTEETPDCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGADGWG 188
+ + KH E +C +++ + T ++ G ++G
Sbjct: 393 ASFSNHQRVHTDKKHYE-CGECGKSFSQKSSLIQHQRFHTGEKPYGCEECGKSFSSEGHL 451
Query: 189 PSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGKTY 248
S A P + + S+V+ ER Y+C +CGK++
Sbjct: 452 RSHQRVHAGERPFKCGECVKSFSH--KRSLVH--------HQRVHSGERPYQCGECGKSF 501
Query: 249 KHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPR 307
G+L H++ HT Y C C K FS+ L+NH ++H R Y C C + F
Sbjct: 502 SQKGNLVLHQRVHTGARPYECGECGKSFSSKGHLRNHQQIHTGDRLYECGECGKSFSHKG 561
Query: 308 ELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSGELEDSG 367
L+ HQ+ H ER E ++ GH L S Q ++ +GE
Sbjct: 562 TLILHQRVHPRERSYGCGECGKSFSSIGH--------LRSHQRVH-------TGE----- 601
Query: 368 LEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFNAAALKNHVRAHHR 425
RP+ CG+CG+++ H SL++H++ H TG Y C C K L+NH R H
Sbjct: 602 ----RPYECGECGKSFSHKRSLVHHQRMH-TGERPYKCGDCGKSFNEKGHLRNHQRVH-- 654
Query: 426 PRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRH 485
TT RP+KC ECG+ + H+G+L+ H+H
Sbjct: 655 ----------------------TT------------ERPFKCGECGKCFSHKGNLILHQH 680
Query: 486 SHRTGE--YQCSLCPRKYPNLMALRNHVRVH-------CKAARRSADIGAEGAPSHLKVE 536
H TGE Y C C + + L H R+H C+A ++ +H +V
Sbjct: 681 GH-TGERPYVCRECGKLFKKKSHLLVHQRIHNGEKPYACEACQKFFR-NKYQLIAHQRVH 738
Query: 537 LPPDPVEAE--AAPHTDQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHG 594
P E T C H+ T P + CS CG F ++ S +H
Sbjct: 739 TGERPYECNDCGKSFTHSSTFCVHKRIHTGEKP-------YECSECGKSFAESSSFTKHK 791
Query: 595 LTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKH 652
H GEK + C +CGKS+ S SL H++ H TG+ + C C K
Sbjct: 792 RVH-TGEK-------------PYECSECGKSFAESSSLTKHKRVH-TGEKPYKCEKCGKL 836
Query: 653 FHTMAAMKNHLRRHSRR 669
F+ + + H H R+
Sbjct: 837 FNKKSHLLVHQSSHWRK 853
Score = 164 bits (416), Expect = 6e-40
Identities = 140/577 (24%), Positives = 226/577 (39%), Gaps = 118/577 (20%)
Query: 821 HTCSDCGHSFPHATGLLSHRPCHPPGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQP 880
H C +CG SF +H+ H ++C C K F + +H + H T +P
Sbjct: 269 HECGECGKSFSKYVSFSNHQRVHTEKKHECGECGKSFSKYVSFSNHQRVH-----TGKRP 323
Query: 881 FLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAEL 940
+ C CG F A + H+R H+ E + E + S + S +
Sbjct: 324 YECGECGKSFSKYASFSNHQR-VHT----------EKKHYECGECGKSFSKYVSFSNHQR 372
Query: 941 LNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAM 1000
++ +R E CG CG+++ S H + + DK G G +
Sbjct: 373 VHTGKRPYE----------CGECGKSFSKYASFSNHQRVHT-----DKKHYECGECGKSF 417
Query: 1001 EMVVDSVLEDIVNSVSG-----EGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCN 1055
+ ++ E G + S EG L + GE RPF+C
Sbjct: 418 SQKSSLIQHQRFHTGEKPYGCEECGKSFSSEGH---LRSHQRVHAGE-------RPFKCG 467
Query: 1056 QCGKTYRHGGSLVNHRKIHQ-TGDFLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPI 1114
+C K++ H SLV+H+++H + C C + + H R H
Sbjct: 468 ECVKSFSHKRSLVHHQRVHSGERPYQCGECGKSFSQKGNLVLHQRVH------------- 514
Query: 1115 PEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARV-KEEVWE 1173
G+ + G + S+K + Q+ + L E K +
Sbjct: 515 ---TGARPYECGECGKSFSSK-----------GHLRNHQQIHTGDRLYECGECGKSFSHK 560
Query: 1174 ETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FG 1231
T + + + PR ER + C CG+S+ G L +H++ H TG +
Sbjct: 561 GTLILHQRVHPR--------------ERSYGCGECGKSFSSIGHLRSHQRVH-TGERPYE 605
Query: 1232 CQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRK 1291
C C K FS+ SL +H+R+H R ++C +CGK+F + L +HQRVH
Sbjct: 606 CGECGKSFSHKRSLVHHQRMHTGERPYKCGDCGKSFNEKGHLRNHQRVH----------- 654
Query: 1292 ATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHS 1349
+RPF+CG+CG+ + H G+L+ H+ H TG+ Y C C K + + L HQR+H+
Sbjct: 655 --TTERPFKCGECGKCFSHKGNLILHQHGH-TGERPYVCRECGKLFKKKSHLLVHQRIHN 711
Query: 1350 ENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREH 1386
+ C C + F + L H R H
Sbjct: 712 GEK----------PYACEACQKFFRNKYQLIAHQRVH 738
Score = 164 bits (415), Expect = 7e-40
Identities = 165/663 (24%), Positives = 261/663 (39%), Gaps = 134/663 (20%)
Query: 58 RHPGSLVNHRRTHETGLFPCTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHL 117
R P + V+ ++ H PC CG + + + H TH + + HR
Sbjct: 80 RTPMAGVSPKKAH-----PCEMCGPILGDILHVADHQGTHHKQ--KLHR----------- 121
Query: 118 QGETVSTDSWGQRLGSSEGW-ENQTKHTEETPDCESVPDPRAA--------------SGT 162
++WG +L S + ++Q +H E P SV + A S +
Sbjct: 122 ------CEAWGNKLYDSGNFHQHQNEHIGEKPYRGSVEEALFAKRCKLHVSGESSVFSES 175
Query: 163 WED-LPTRQREGL----ASHPGPEDGAD--------------GWGPSTNSARAPPLPIPA 203
+D LP R GL ASH G + + G S +
Sbjct: 176 GKDFLP---RSGLLQQEASHTGEKSNSKTECVSPIQCGGAHYSCGESMKHFSTKHILSQH 232
Query: 204 SSLLSNLEQYLA-ESVVNFTGGQEPTQSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSHT 262
LL+ E Y+ E +F+ + E++++C +CGK++ S +NH++ HT
Sbjct: 233 QRLLTREECYVCCECGKSFSKYASLSNHQRVHTEKKHECGECGKSFSKYVSFSNHQRVHT 292
Query: 263 LGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQE 322
+ C C K FS ++ NH R+H RPY C C + F HQ+ H ++
Sbjct: 293 EKKHECGECGKSFSKYVSFSNHQRVHTGKRPYECGECGKSFSKYASFSNHQRVHTEKKHY 352
Query: 323 PRWE-----EKGMPTTNG---HTDESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPF 374
E K + +N HT + + + + A S + + + +
Sbjct: 353 ECGECGKSFSKYVSFSNHQRVHTGKRPYECGECGKSFSKYASFSNHQRVH----TDKKHY 408
Query: 375 RCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFNAAALKNHVRAHHRPRQ-GVG 431
CG+CG+++ SLI H++ H TG Y C C K + L++H R H R G
Sbjct: 409 ECGECGKSFSQKSSLIQHQRFH-TGEKPYGCEECGKSFSSEGHLRSHQRVHAGERPFKCG 467
Query: 432 ENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTG- 490
E + L+ + H E RPY+C ECG+++ +G+LV H+ H TG
Sbjct: 468 ECVKSFSHKRSLVHHQRVHSGE---------RPYQCGECGKSFSQKGNLVLHQRVH-TGA 517
Query: 491 -EYQCSLCPRKYPNLMALRNHVRVHCKAARRSADIGAEGAPSHLKVELPPDPVEAEAAPH 549
Y+C C + + + LRNH ++H R + G G K L
Sbjct: 518 RPYECGECGKSFSSKGHLRNHQQIH--TGDRLYECGECGKSFSHKGTLIL---------- 565
Query: 550 TDQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTET 609
H H E ++ C CG F L H H GE
Sbjct: 566 ----HQRVHPRE-----------RSYGCGECGKSFSSIGHLRSHQRVH-TGE-------- 601
Query: 610 TMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHS 667
R + C +CGKS+ H SL++H++ H TG+ + CG C K F+ ++NH R H+
Sbjct: 602 -----RPYECGECGKSFSHKRSLVHHQRMH-TGERPYKCGDCGKSFNEKGHLRNHQRVHT 655
Query: 668 RRR 670
R
Sbjct: 656 TER 658
Score = 159 bits (402), Expect = 2e-38
Identities = 161/654 (24%), Positives = 242/654 (37%), Gaps = 122/654 (18%)
Query: 1171 VWEETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGHF 1230
V +E + I + ET + S ++ CE+CG + +H+ +H
Sbjct: 60 VEDEAAPSKQSIYIQRETQVRTPMAGVSPKKAHPCEMCGPILGDILHVADHQGTHHKQKL 119
Query: 1231 G-CQACSKGFSNLMSLKNHRRIHADPRRFR----------------------CSECGKAF 1267
C+A + + H+ H + +R SE GK F
Sbjct: 120 HRCEAWGNKLYDSGNFHQHQNEHIGEKPYRGSVEEALFAKRCKLHVSGESSVFSESGKDF 179
Query: 1268 RLRKQLASHQRVHMERRGGGGTRKATREDRPFRCG----QCGRTYRHAGS---LLNHRRS 1320
R L + H + T + P +CG CG + +H + L H+R
Sbjct: 180 LPRSGLLQQEASHTGEKSNSKTECVS----PIQCGGAHYSCGESMKHFSTKHILSQHQRL 235
Query: 1321 HETGQ-YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSL 1379
+ Y C C K++S +L +HQR+H+E + C CG+SF S
Sbjct: 236 LTREECYVCCECGKSFSKYASLSNHQRVHTEKKHE-----------CGECGKSFSKYVSF 284
Query: 1380 ERHLREHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRPGER 1439
H R H TE++ G+ G + + + + Q + T G P GE
Sbjct: 285 SNHQRVH--TEKKHECGECGK--SFSKYVSFSNHQRVHT---GKRPY--------ECGEC 329
Query: 1440 SQSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSPCH 1499
+S + AS NH VH H
Sbjct: 330 GKSFSKYAS----------------------FSNHQ----------------RVHTEKKH 351
Query: 1500 --AGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHS-SCSQCGKTYCQSGSLLNHNTNKTDR 1556
G+C G + S S+ N ++ G C +CGK++ + S NH TD+
Sbjct: 352 YECGEC---GKSFSKYVSFSNHQ---RVHTGKRPYECGECGKSFSKYASFSNHQRVHTDK 405
Query: 1557 -HY-CLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQV 1614
HY C C K F + H H + + C +CGK+F S L SH + HA
Sbjct: 406 KHYECGECGKSFSQKSSLIQHQRFHTGEKPYGCEECGKSFSSEGHLRSHQRVHAGERPFK 465
Query: 1615 PAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVER-ARGGQAVTSMAAEDK 1673
+ ++ K Q V G E P GE + ++ G V
Sbjct: 466 CGECVKSFSHKRSLVHHQRVHSG---------ERPYQCGECGKSFSQKGNLVLHQRVHTG 516
Query: 1674 ERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLCPKLLPNLLSLKNHSRTHTDPKRH 1732
RP+ C +CG+S+ G L NHQ+ HT LY C C K + +L H R H + +
Sbjct: 517 ARPYECGECGKSFSSKGHLRNHQQIHTGDRLYECGECGKSFSHKGTLILHQRVHPRERSY 576
Query: 1733 CCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
C CGK+F + L H RVH E P+ C C + F + S V HQ+ H E
Sbjct: 577 GCGECGKSFSSIGHLRSHQRVHT-GERPYECGECGKSFSHKRSLVHHQRMHTGE 629
Score = 148 bits (373), Expect = 5e-35
Identities = 158/712 (22%), Positives = 254/712 (35%), Gaps = 171/712 (24%)
Query: 266 YPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGER----- 320
+PC +C +++ + +H H + + + C +HQ H GE+
Sbjct: 92 HPCEMCGPILGDILHVADHQGTHHKQKLHRCEAWGNKLYDSGNFHQHQNEHIGEKPYRGS 151
Query: 321 -QEPRWEEKGMPTTNGHTD---ESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRC 376
+E + ++ +G + ES +D LP + +L E S +GE +S E P +C
Sbjct: 152 VEEALFAKRCKLHVSGESSVFSESGKDFLPRSGLLQ--QEASHTGEKSNSKTECVSPIQC 209
Query: 377 G-----------------------------------DCGRTYRHAGSLINHRKSHQTGVY 401
G +CG+++ SL NH++ H +
Sbjct: 210 GGAHYSCGESMKHFSTKHILSQHQRLLTREECYVCCECGKSFSKYASLSNHQRVHTEKKH 269
Query: 402 PCSLCSKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLD 461
C C K + NH R H + GE G+ + H +
Sbjct: 270 ECGECGKSFSKYVSFSNHQRVHTEKKHECGECGKSFSKYVSFSNHQRVHTGK-------- 321
Query: 462 HRPYKCSECGRAYRHRGSLVNHRHSHRTGE-YQCSLCPRKYPNLMALRNHVRVHCKAARR 520
RPY+C ECG+++ S NH+ H + Y+C C + + ++ NH RVH +R
Sbjct: 322 -RPYECGECGKSFSKYASFSNHQRVHTEKKHYECGECGKSFSKYVSFSNHQRVH--TGKR 378
Query: 521 SADIGAEGAPSHLKVELPPDPVEAEAAPHTDQDHVCKHEEEATDITPAADKTAAHICSIC 580
+ G G HTD+ H + C C
Sbjct: 379 PYECGECGKSFSKYASF-----SNHQRVHTDKKH--------------------YECGEC 413
Query: 581 GLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQ 640
G F SL +H H GEK + C +CGKS+ G L +H++ H
Sbjct: 414 GKSFSQKSSLIQHQRFH-TGEKP-------------YGCEECGKSFSSEGHLRSHQRVHA 459
Query: 641 -TGDFSCGACAKHFHTMAAMKNHLRRHSRRRSRRHRKRAGGASGGREAKLLAAESWTREL 699
F CG C K F ++ +H R HS R ++ G S ++ L+ +
Sbjct: 460 GERPFKCGECVKSFSHKRSLVHHQRVHSGERP--YQCGECGKSFSQKGNLVLHQ------ 511
Query: 700 EDNEGLESPQDPSGESPHGAEGNLESDGDCLQAESEGDKCGLERDETHFQGDK--ESGGT 757
+ +G P+ G+C +S K L + GD+ E G
Sbjct: 512 ---------RVHTGARPYEC-------GEC--GKSFSSKGHLRNHQQIHTGDRLYECGEC 553
Query: 758 GEGLERKDASLLDNLDIPGEEGGGTHFC----DSLTGVDEDQKPATGQPNSSSHSANAVT 813
G+ K +L P E G C S+ + Q+ TG+
Sbjct: 554 GKSFSHKGTLILHQRVHPRERSYGCGECGKSFSSIGHLRSHQRVHTGE------------ 601
Query: 814 GWQAGAAHTCSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNH-- 870
+ C +CG SF H L+ H+ H Y+C C K F+ LR+H + H
Sbjct: 602 -----RPYECGECGKSFSHKRSLVHHQRMHTGERPYKCGDCGKSFNEKGHLRNHQRVHTT 656
Query: 871 -RP---GEA-----------------TSAQPFLCCLCGMIFPGRAGYRLHRR 901
RP GE T +P++C CG +F ++ +H+R
Sbjct: 657 ERPFKCGECGKCFSHKGNLILHQHGHTGERPYVCRECGKLFKKKSHLLVHQR 708
Score = 148 bits (373), Expect = 5e-35
Identities = 209/924 (22%), Positives = 327/924 (35%), Gaps = 206/924 (22%)
Query: 375 RCGDCGRTYRHAGSLINHRKSHQTGVYPCSLCSKQLFNAAALKNHVRAHHRPRQGVGENG 434
RC G +G+ H+ H G P ++ A K HV E+G
Sbjct: 121 RCEAWGNKLYDSGNFHQHQNEH-IGEKPYRGSVEEALFAKRCKLHVSGESSV---FSESG 176
Query: 435 QPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCS----ECGRAYRHRGSLVNHRHSHRTG 490
+ +P + LL E +H E+ + T P +C CG + +H + H
Sbjct: 177 KDFLPRSGLLQQEASHTGEKSNSKTECVSPIQCGGAHYSCGESMKHFST------KHILS 230
Query: 491 EYQCSLCPRKYPNLMALRNHVRVHCKAARRSADIGAEGAPSHLKVELPPDPVEAEAAPHT 550
++Q L R V C+ + + + +H +V HT
Sbjct: 231 QHQRLLT----------REECYVCCECGKSFSKYAS--LSNHQRV-------------HT 265
Query: 551 DQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTETT 610
++ KHE C CG F S H H + E
Sbjct: 266 EK----KHE-----------------CGECGKSFSKYVSFSNHQRVHTEKKHE------- 297
Query: 611 MSPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHSR 668
C +CGKS+ S NH++ H TG + CG C K F A+ NH R H+
Sbjct: 298 --------CGECGKSFSKYVSFSNHQRVH-TGKRPYECGECGKSFSKYASFSNHQRVHTE 348
Query: 669 RRSRRHRKRAGGASGGREAKLLAAESWTRELEDNEGLESPQDPSGESPHGAEGNLESDGD 728
++ G G +K ++ + R E + S + + N +
Sbjct: 349 KKHYEC-----GECGKSFSKYVSFSNHQRVHTGKRPYECGECGKSFSKYASFSNHQR--- 400
Query: 729 CLQAESEGDKCGLERDETHFQGDKESGGTGEGLERKDASLLDNLDIPGEEGGGTHFCDSL 788
+ D+ H+ E G G+ +K + + GE+ G C
Sbjct: 401 ------------VHTDKKHY----ECGECGKSFSQKSSLIQHQRFHTGEKPYGCEEC--- 441
Query: 789 TGVDEDQKPATGQPNSSSHSANAVTGWQAGAA-HTCSDCGHSFPHATGLLSHRPCHP-PG 846
G+ SS + AG C +C SF H L+ H+ H
Sbjct: 442 -----------GKSFSSEGHLRSHQRVHAGERPFKCGECVKSFSHKRSLVHHQRVHSGER 490
Query: 847 IYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHRRQAHSS 906
YQC C K F L H + H T A+P+ C CG F + R H+ Q H+
Sbjct: 491 PYQCGECGKSFSQKGNLVLHQRVH-----TGARPYECGECGKSFSSKGHLRNHQ-QIHTG 544
Query: 907 SGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSAGYGHICGCCGQT 966
+ E E + S L + ++ +R YG CG CG++
Sbjct: 545 DRLYE----------CGECGKSFSHKGTLILHQRVHPRERS--------YG--CGECGKS 584
Query: 967 YDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDIVNSVSGEGGDAKSQE 1026
+ +G L R HQ +G + P G G + S +V+ G+ +
Sbjct: 585 FSSIGHL-RSHQRVHTG----ERPYECGECGKSF-----SHKRSLVHHQRMHTGERPYKC 634
Query: 1027 GAGTPLGDSLCIQG---GESLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGD--FLC 1081
G G S +G + RPF+C +CGK + H G+L+ H+ H TG+ ++C
Sbjct: 635 G---DCGKSFNEKGHLRNHQRVHTTERPFKCGECGKCFSHKGNLILHQHGH-TGERPYVC 690
Query: 1082 PVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAAGSSELQVGPIPEGGSNKPQHMAE 1141
C + + ++HL H R E P A + + + NK Q +A
Sbjct: 691 RECGKLFKK----KSHLLVHQRIHNGEK-----PYACEACQ-------KFFRNKYQLIAH 734
Query: 1142 EGPGQAEVEKLQEELKVEPLEEVARVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSER 1201
+ E P E K T + R+ T EK
Sbjct: 735 QRVHTGE----------RPYECNDCGKSFTHSSTFC----VHKRIHTGEK---------- 770
Query: 1202 PFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPRRFR 1259
P+ C CG+S+ + S H++ H TG + C C K F+ SL H+R+H + ++
Sbjct: 771 PYECSECGKSFAESSSFTKHKRVH-TGEKPYECSECGKSFAESSSLTKHKRVHTGEKPYK 829
Query: 1260 CSECGKAFRLRKQLASHQRVHMER 1283
C +CGK F + L HQ H +
Sbjct: 830 CEKCGKLFNKKSHLLVHQSSHWRK 853
Score = 61.2 bits (147), Expect = 9e-09
Identities = 33/96 (34%), Positives = 47/96 (48%), Gaps = 15/96 (15%)
Query: 7 SLSCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNH 66
S C +C + F S+ L H+ + + RPY C +CG+ + H SLV+H
Sbjct: 575 SYGCGECGKSFSSIGHLRSHQRV------------HTGERPYECGECGKSFSHKRSLVHH 622
Query: 67 RRTHETGLFP--CTTCGKDFSNPMALKSHMRTHAPE 100
+R H TG P C CGK F+ L++H R H E
Sbjct: 623 QRMH-TGERPYKCGDCGKSFNEKGHLRNHQRVHTTE 657
Score = 55.8 bits (133), Expect = 4e-07
Identities = 30/89 (33%), Positives = 42/89 (47%), Gaps = 12/89 (13%)
Query: 9 SCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRR 68
SC + +HF + LS+H+ LL EE Y C +CG+ + SL NH+R
Sbjct: 215 SCGESMKHFSTKHILSQHQRLL------TREEC------YVCCECGKSFSKYASLSNHQR 262
Query: 69 THETGLFPCTTCGKDFSNPMALKSHMRTH 97
H C CGK FS ++ +H R H
Sbjct: 263 VHTEKKHECGECGKSFSKYVSFSNHQRVH 291
Score = 52.8 bits (125), Expect = 3e-06
Identities = 28/94 (29%), Positives = 42/94 (44%), Gaps = 15/94 (15%)
Query: 9 SCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRR 68
+C CQ+ F + +L H+ + + RPY C CG+ + H + H+R
Sbjct: 717 ACEACQKFFRNKYQLIAHQRV------------HTGERPYECNDCGKSFTHSSTFCVHKR 764
Query: 69 THETGLFP--CTTCGKDFSNPMALKSHMRTHAPE 100
H TG P C+ CGK F+ + H R H E
Sbjct: 765 IH-TGEKPYECSECGKSFAESSSFTKHKRVHTGE 797
Score = 51.6 bits (122), Expect = 7e-06
Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 2/79 (2%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
CS+CGK++ +S S H T + C C K F + H H + + C C
Sbjct: 774 CSECGKSFAESSSFTKHKRVHTGEKPYECSECGKSFAESSSLTKHKRVHTGEKPYKCEKC 833
Query: 1591 GKAFESHQELASHLQAHAR 1609
GK F L H +H R
Sbjct: 834 GKLFNKKSHLLVHQSSHWR 852
>gi|156627573 zinc finger protein 836 [Homo sapiens]
Length = 936
Score = 212 bits (539), Expect = 3e-54
Identities = 187/791 (23%), Positives = 293/791 (37%), Gaps = 145/791 (18%)
Query: 1050 RPFRCNQCGKTYRHGGSLVNHRKIHQT-GDFLCPVCSRCYPNLAAYRNHLRNHPRCKGSE 1108
+P+ C CGK +R SL+NH+ +H T + C C + + + H H R G
Sbjct: 216 KPYMCKGCGKAFRVSSSLINHQMVHTTEKPYKCNECGKAFHRGSLLTIHQIVHTR--GKP 273
Query: 1109 PQVGPIPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVK 1168
Q G + + V KP E G ++ L ++ E+ +
Sbjct: 274 YQCGVCGKIFRQNSDLVNHRRSHTGEKPYKCNECGKSFSQSYNLAIHQRIHTGEKPYKCN 333
Query: 1169 EEVWEETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTG 1228
E +T +G + Q + E+P+ C++CG+ ++ +L+NH++ H TG
Sbjct: 334 E--CGKTFKQGSCLTTH--------QIIHTGEKPYQCDICGKVFRQNSNLVNHQRIH-TG 382
Query: 1229 H--FGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVH------ 1280
+ C C K FS +L H+ +H+ + ++C ECGK F+ L +HQ +H
Sbjct: 383 EKPYKCNICGKSFSQSSNLATHQTVHSGNKPYKCDECGKTFKRSSSLTTHQIIHTGEKPY 442
Query: 1281 ---------MERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCP 1329
+R +++ ++P++C +CG+ + L+ HRR H TG+ Y C
Sbjct: 443 TCDVCDKVFSQRSQLARHQRSHTGEKPYKCNECGKVFSQTSHLVGHRRIH-TGEKPYKCD 501
Query: 1330 TCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHEET 1389
C K + L H+ +H+ +R +C CG+ F L RHLR H
Sbjct: 502 KCGKAFKQGSLLTRHKIIHTREKR----------YQCGECGKVFSENSCLVRHLRIHTGE 551
Query: 1390 EREPANGQGGLDGTAASEANLTGSQGLETQL-GGAEPVPHLEDG-VPRPGERSQSPIRAA 1447
+ N G + N +G+ + ++ G +P E G V R +R
Sbjct: 552 QPYKCNVCGKV-------FNYSGNLSIHKRIHTGEKPFQCNECGTVFRNYSCLARHLRIH 604
Query: 1448 SSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSPCHAGDCQLNG 1507
+ + P + V G + N SG S P +C G
Sbjct: 605 TGQKPYKCN----------VCGKVFNDSG-------NLSNHKRIHTGEKPFQCNEC---G 644
Query: 1508 PTLSHMDSWDNRDNSSQLQPGSHS-SCSQCGKTYCQSGSLLNH----------------- 1549
S+ + ++ G C+ CGK Y Q SL H
Sbjct: 645 KVFSY---YSCLARHRKIHTGEKPYKCNDCGKAYTQRSSLTKHLIIHTGEKPYNCNEFGG 701
Query: 1550 -------------NTNKTDRHYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFES 1596
N H C C + F + H H + C +CG+ F S
Sbjct: 702 AFIQSSKLARYHRNPTGEKPHKCSHCGRTFSHITGLTYHQRRHTGEMPYKCIECGQVFNS 761
Query: 1597 HQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESV 1656
LA H + H TGE GK S R
Sbjct: 762 TSNLARHRRIH--------------------TGEKPYKCNECGKVFRHQSTLAR------ 795
Query: 1657 ERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPN 1715
+ E+P+ C +CG+++R L+NHQK HT Y C+ C K
Sbjct: 796 ----------HRSIHTGEKPYVCNECGKAFRVRSILVNHQKMHTGDKPYKCNECGKAFIE 845
Query: 1716 LLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRIS 1775
L H R HT K + C CGKAF + L H +H+ E P+ C C + F R
Sbjct: 846 RSKLVYHQRNHTGEKPYKCIECGKAFGRFSCLNKHQMIHS-GEKPYKCNECGKSFISRSG 904
Query: 1776 FVQHQQQHQEE 1786
+HQ +H E
Sbjct: 905 LTKHQTKHTAE 915
Score = 188 bits (477), Expect = 5e-47
Identities = 186/811 (22%), Positives = 321/811 (39%), Gaps = 133/811 (16%)
Query: 605 SRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGD-FSCGACAKHFHTMAAMKNHL 663
++ E T + + C+ CGK++R S SLINH+ H T + C C K FH + + H
Sbjct: 206 TQLEKTHIREKPYMCKGCGKAFRVSSSLINHQMVHTTEKPYKCNECGKAFHRGSLLTIHQ 265
Query: 664 RRHSRRRSRR----------------HRKRAGGASGGREAKLLAAESWTRELEDNEGLES 707
H+R + + HR+ G + + + S + L ++ +
Sbjct: 266 IVHTRGKPYQCGVCGKIFRQNSDLVNHRRSHTGEKPYKCNECGKSFSQSYNLAIHQRIH- 324
Query: 708 PQDPSGESPHGAE--GNLESDGDCLQAESEGDKCGLERDETHFQGDKESGGTGEGLERKD 765
+GE P+ G G CL + E +Q D + R++
Sbjct: 325 ----TGEKPYKCNECGKTFKQGSCLTTHQI-----IHTGEKPYQCD-----ICGKVFRQN 370
Query: 766 ASLLDNLDI-PGEEGGGTHFCDSLTGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHTCS 824
++L+++ I GE+ + C + AT Q + HS N + C
Sbjct: 371 SNLVNHQRIHTGEKPYKCNICGK--SFSQSSNLATHQ---TVHSGN--------KPYKCD 417
Query: 825 DCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLC 883
+CG +F ++ L +H+ H Y C +C K F L H ++H T +P+ C
Sbjct: 418 ECGKTFKRSSSLTTHQIIHTGEKPYTCDVCDKVFSQRSQLARHQRSH-----TGEKPYKC 472
Query: 884 CLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAE-AAPARSPPLQLSEAELLN 942
CG +F + + + R+ H+ GE+ + A L+ ++++
Sbjct: 473 NECGKVF-SQTSHLVGHRRIHT-----------GEKPYKCDKCGKAFKQGSLLTRHKIIH 520
Query: 943 QLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEM 1002
++ + CG CG+ + + L RH + + + P V G
Sbjct: 521 TREKRYQ----------CGECGKVFSENSCLVRHLRIHTG-----EQPYKCNVCGKVFNY 565
Query: 1003 VVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYR 1062
+ + +++ G GT + C+ + Q +P++CN CGK +
Sbjct: 566 SGNLSIHKRIHT----GEKPFQCNECGTVFRNYSCLARHLRIHTGQ-KPYKCNVCGKVFN 620
Query: 1063 HGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEP-QVGPIPEAAG 1119
G+L NH++IH TG+ F C C + + + H + H G +P + +A
Sbjct: 621 DSGNLSNHKRIH-TGEKPFQCNECGKVFSYYSCLARHRKIH---TGEKPYKCNDCGKAYT 676
Query: 1120 SSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKEEVWEETTVKG 1179
+ KP + E G + KL + E+ + + + G
Sbjct: 677 QRSSLTKHLIIHTGEKPYNCNEFGGAFIQSSKLARYHRNPTGEKPHKCSHCGRTFSHITG 736
Query: 1180 EEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSK 1237
R T E P+ C CG+ + +L HR+ H TG + C C K
Sbjct: 737 LTYHQRRHT----------GEMPYKCIECGQVFNSTSNLARHRRIH-TGEKPYKCNECGK 785
Query: 1238 GFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDR 1297
F + +L HR IH + + C+ECGKAFR+R L +HQ++H D+
Sbjct: 786 VFRHQSTLARHRSIHTGEKPYVCNECGKAFRVRSILVNHQKMH-------------TGDK 832
Query: 1298 PFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRR 1355
P++C +CG+ + L+ H+R+H TG+ Y C C K + L HQ +HS +
Sbjct: 833 PYKCNECGKAFIERSKLVYHQRNH-TGEKPYKCIECGKAFGRFSCLNKHQMIHSGEK--- 888
Query: 1356 AGRSRRTAVRCALCGRSFPGRGSLERHLREH 1386
+C CG+SF R L +H +H
Sbjct: 889 -------PYKCNECGKSFISRSGLTKHQTKH 912
Score = 167 bits (423), Expect = 9e-41
Identities = 178/705 (25%), Positives = 257/705 (36%), Gaps = 174/705 (24%)
Query: 46 RPYRCQQCGRGYRHPGSLVNHRRTHETGLFP--CTTCGKDFSNPMALKSHMRTHAPEGRR 103
+PY+C CG+ +R LVNHRR+H TG P C CGK FS L H R H E
Sbjct: 272 KPYQCGVCGKIFRQNSDLVNHRRSH-TGEKPYKCNECGKSFSQSYNLAIHQRIHTGE--- 327
Query: 104 RHRPPRPKEATPHLQGETVSTDSWGQRLGSSEGWENQTKHTEETP-DCESVPDPRAASGT 162
P+ E T G L + +Q HT E P C+
Sbjct: 328 ----------KPYKCNECGKTFKQGSCLTT-----HQIIHTGEKPYQCDICGKV------ 366
Query: 163 WEDLPTRQREGLASHPGPEDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFT 222
RQ L +H G + + + S SNL +
Sbjct: 367 -----FRQNSNLVNHQRIHTGEKPYKCNICGK--------SFSQSSNLATHQTVH----- 408
Query: 223 GGQEPTQSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMAL 281
G +P YKC +CGKT+K + SLT H+ HT Y C +C K FS L
Sbjct: 409 SGNKP-----------YKCDECGKTFKRSSSLTTHQIIHTGEKPYTCDVCDKVFSQRSQL 457
Query: 282 KNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGER--------------------- 320
H R H +PY C C +VF L+ H++ H GE+
Sbjct: 458 ARHQRSHTGEKPYKCNECGKVFSQTSHLVGHRRIHTGEKPYKCDKCGKAFKQGSLLTRHK 517
Query: 321 ----QEPRWE--EKGMPTTNG---------HTDESSQDQLPSAQMLNGSAELSTSGELED 365
+E R++ E G + HT E ++ N S LS +
Sbjct: 518 IIHTREKRYQCGECGKVFSENSCLVRHLRIHTGEQPYKCNVCGKVFNYSGNLSIHKRIHT 577
Query: 366 SGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTGV--YPCSLCSKQLFNAAALKNHVRAH 423
+PF+C +CG +R+ L H + H TG Y C++C K ++ L NH R H
Sbjct: 578 GE----KPFQCNECGTVFRNYSCLARHLRIH-TGQKPYKCNVCGKVFNDSGNLSNHKRIH 632
Query: 424 --HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLV 481
+P Q E G+ + L H E +PYKC++CG+AY R SL
Sbjct: 633 TGEKPFQ-CNECGKVFSYYSCLARHRKIHTGE---------KPYKCNDCGKAYTQRSSLT 682
Query: 482 NHR---------------------------HSHRTGE--YQCSLCPRKYPNLMALRNHVR 512
H H + TGE ++CS C R + ++ L H R
Sbjct: 683 KHLIIHTGEKPYNCNEFGGAFIQSSKLARYHRNPTGEKPHKCSHCGRTFSHITGLTYHQR 742
Query: 513 VHC-KAARRSADIG-----AEGAPSHLKVELPPDPVEAEAAPHT--DQDHVCKHEEEATD 564
H + + + G H ++ P + Q + +H T
Sbjct: 743 RHTGEMPYKCIECGQVFNSTSNLARHRRIHTGEKPYKCNECGKVFRHQSTLARHRSIHTG 802
Query: 565 ITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGK 624
P ++C+ CG F L H H G+K + C +CGK
Sbjct: 803 EKP-------YVCNECGKAFRVRSILVNHQKMH-TGDKP-------------YKCNECGK 841
Query: 625 SYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHS 667
++ L+ H++ H TG+ + C C K F + + H HS
Sbjct: 842 AFIERSKLVYHQRNH-TGEKPYKCIECGKAFGRFSCLNKHQMIHS 885
Score = 165 bits (418), Expect = 3e-40
Identities = 174/687 (25%), Positives = 262/687 (38%), Gaps = 134/687 (19%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C++C + F L+ H +++H +PY+C CG+ +R +LVNH+R
Sbjct: 332 CNECGKTFKQGSCLTTH-QIIHTGE-----------KPYQCDICGKVFRQNSNLVNHQRI 379
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHLQGETVSTDSW 127
H TG P C CGK FS L +H H+ ++P + E G+T
Sbjct: 380 H-TGEKPYKCNICGKSFSQSSNLATHQTVHSG-----NKPYKCDEC-----GKTFKR--- 425
Query: 128 GQRLGSSEGWENQTKHTEETPDCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGADGW 187
SS +Q HT E P V D + QR LA H G
Sbjct: 426 -----SSSLTTHQIIHTGEKPYTCDVCDKVFS----------QRSQLARHQRSHTG---- 466
Query: 188 GPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGKT 247
P + S + ++ TG E+ YKC +CGK
Sbjct: 467 -------EKPYKCNECGKVFSQTSHLVGHRRIH-TG------------EKPYKCDKCGKA 506
Query: 248 YKHAGSLTNHRQSHTLGI-YPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLP 306
+K LT H+ HT Y C C K FS L H R+H +PY C C +VF
Sbjct: 507 FKQGSLLTRHKIIHTREKRYQCGECGKVFSENSCLVRHLRIHTGEQPYKCNVCGKVFNYS 566
Query: 307 RELLEHQQSHEGERQEPRWEEKGMPTTNG---------HTDESSQDQLPSAQMLNGSAEL 357
L H++ H GE+ + E G N HT + ++ N S L
Sbjct: 567 GNLSIHKRIHTGEKPF-QCNECGTVFRNYSCLARHLRIHTGQKPYKCNVCGKVFNDSGNL 625
Query: 358 STSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTGV--YPCSLCSKQLFNAAA 415
S + +PF+C +CG+ + + L HRK H TG Y C+ C K ++
Sbjct: 626 SNHKRIHTGE----KPFQCNECGKVFSYYSCLARHRKIH-TGEKPYKCNDCGKAYTQRSS 680
Query: 416 LKNHVRAHHRPRQ-GVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAY 474
L H+ H + E G + + L + +PT +P+KCS CGR +
Sbjct: 681 LTKHLIIHTGEKPYNCNEFGGAFIQSSKLA------RYHRNPT---GEKPHKCSHCGRTF 731
Query: 475 RHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHC-KAARRSADIGAEGAPS 531
H L H+ H TGE Y+C C + + + L H R+H + + + G
Sbjct: 732 SHITGLTYHQRRH-TGEMPYKCIECGQVFNSTSNLARHRRIHTGEKPYKCNECG------ 784
Query: 532 HLKVELPPDPVEAEAAPHT-DQDHVCKHEEEATDITP---------AADKTAAHICSICG 581
KV + + HT ++ +VC +A + DK + C+ CG
Sbjct: 785 --KVFRHQSTLARHRSIHTGEKPYVCNECGKAFRVRSILVNHQKMHTGDKP--YKCNECG 840
Query: 582 LLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQ- 640
F + L H H GEK + C +CGK++ L H+ H
Sbjct: 841 KAFIERSKLVYHQRNH-TGEKP-------------YKCIECGKAFGRFSCLNKHQMIHSG 886
Query: 641 TGDFSCGACAKHFHTMAAMKNHLRRHS 667
+ C C K F + + + H +H+
Sbjct: 887 EKPYKCNECGKSFISRSGLTKHQTKHT 913
Score = 153 bits (387), Expect = 1e-36
Identities = 133/518 (25%), Positives = 211/518 (40%), Gaps = 84/518 (16%)
Query: 204 SSLLSNLEQYLAESVVNFTGGQE--------PTQSPPAE-EERRYKCSQCGKTYKHAGSL 254
SSL+S L++ L N + E PTQ E+ Y C CGK ++ + SL
Sbjct: 174 SSLVSPLQRILPSVQTNISKKYENEFLQLSLPTQLEKTHIREKPYMCKGCGKAFRVSSSL 233
Query: 255 TNHRQSHTLGI-YPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQ 313
NH+ HT Y C C K F L H +H + +PY C C ++FR +L+ H+
Sbjct: 234 INHQMVHTTEKPYKCNECGKAFHRGSLLTIHQIVHTRGKPYQCGVCGKIFRQNSDLVNHR 293
Query: 314 QSHEGERQEPRWEEKGMPTTNG---------HTDESSQDQLPSAQMLNGSAELSTSGELE 364
+SH GE+ + E G + HT E + + L+T +
Sbjct: 294 RSHTGEKPY-KCNECGKSFSQSYNLAIHQRIHTGEKPYKCNECGKTFKQGSCLTTHQIIH 352
Query: 365 DSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFNAAALKNHVRA 422
+P++C CG+ +R +L+NH++ H TG Y C++C K ++ L H
Sbjct: 353 TG----EKPYQCDICGKVFRQNSNLVNHQRIH-TGEKPYKCNICGKSFSQSSNLATHQTV 407
Query: 423 H--HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTL-------------------D 461
H ++P + E G+ + L + H E+ T +
Sbjct: 408 HSGNKPYK-CDECGKTFKRSSSLTTHQIIHTGEKPYTCDVCDKVFSQRSQLARHQRSHTG 466
Query: 462 HRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHCKAAR 519
+PYKC+ECG+ + LV HR H TGE Y+C C + + L H +H + R
Sbjct: 467 EKPYKCNECGKVFSQTSHLVGHRRIH-TGEKPYKCDKCGKAFKQGSLLTRHKIIHTREKR 525
Query: 520 ----RSADIGAEGA--PSHLKVELPPDPVEAEAA--PHTDQDHVCKHEEEATDITPAADK 571
+ +E + HL++ P + ++ H+ T P
Sbjct: 526 YQCGECGKVFSENSCLVRHLRIHTGEQPYKCNVCGKVFNYSGNLSIHKRIHTGEKPFQ-- 583
Query: 572 TAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGS 631
C+ CG +F + L RH H G+K + C CGK + SG+
Sbjct: 584 -----CNECGTVFRNYSCLARHLRIH-TGQK-------------PYKCNVCGKVFNDSGN 624
Query: 632 LINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHS 667
L NH++ H TG+ F C C K F + + H + H+
Sbjct: 625 LSNHKRIH-TGEKPFQCNECGKVFSYYSCLARHRKIHT 661
Score = 134 bits (337), Expect = 8e-31
Identities = 115/481 (23%), Positives = 200/481 (41%), Gaps = 74/481 (15%)
Query: 949 EALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVL 1008
+ + + G + CG CG+ + L H +S + + P G + + +
Sbjct: 265 QIVHTRGKPYQCGVCGKIFRQNSDLVNHRRSHTG-----EKPYKCNECGKSFSQSYNLAI 319
Query: 1009 EDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYRHGGSLV 1068
+++ GE ++ G G L ++ +P++C+ CGK +R +LV
Sbjct: 320 HQRIHT--GEKPYKCNECGKTFKQGSCLTTH---QIIHTGEKPYQCDICGKVFRQNSNLV 374
Query: 1069 NHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEP----QVGPIPEAAGSSE 1122
NH++IH TG+ + C +C + + + H H G++P + G + SS
Sbjct: 375 NHQRIH-TGEKPYKCNICGKSFSQSSNLATHQTVH---SGNKPYKCDECGKTFKR--SSS 428
Query: 1123 LQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKE--EVWEETT-VKG 1179
L I G KP ++ +L + E+ + E +V+ +T+ + G
Sbjct: 429 LTTHQIIHTG-EKPYTCDVCDKVFSQRSQLARHQRSHTGEKPYKCNECGKVFSQTSHLVG 487
Query: 1180 EEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSH-QTGHFGCQACSKG 1238
R+ T EK P+ C+ CG+++K L H+ H + + C C K
Sbjct: 488 HR---RIHTGEK----------PYKCDKCGKAFKQGSLLTRHKIIHTREKRYQCGECGKV 534
Query: 1239 FSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRP 1298
FS L H RIH + ++C+ CGK F L+ H+R+H ++P
Sbjct: 535 FSENSCLVRHLRIHTGEQPYKCNVCGKVFNYSGNLSIHKRIH-------------TGEKP 581
Query: 1299 FRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENR---- 1352
F+C +CG +R+ L H R H TGQ Y C C K +++ L +H+R+H+ +
Sbjct: 582 FQCNECGTVFRNYSCLARHLRIH-TGQKPYKCNVCGKVFNDSGNLSNHKRIHTGEKPFQC 640
Query: 1353 --------------RRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHEETEREPANGQG 1398
R R + +C CG+++ R SL +HL H + N G
Sbjct: 641 NECGKVFSYYSCLARHRKIHTGEKPYKCNDCGKAYTQRSSLTKHLIIHTGEKPYNCNEFG 700
Query: 1399 G 1399
G
Sbjct: 701 G 701
Score = 82.0 bits (201), Expect = 5e-15
Identities = 42/115 (36%), Positives = 59/115 (51%), Gaps = 2/115 (1%)
Query: 1673 KERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKR 1731
+E+P+ C CG+++R + SL+NHQ HTT Y C+ C K L H HT K
Sbjct: 214 REKPYMCKGCGKAFRVSSSLINHQMVHTTEKPYKCNECGKAFHRGSLLTIHQIVHTRGKP 273
Query: 1732 HCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
+ C +CGK FR + L H R H E P+ C C + F + + HQ+ H E
Sbjct: 274 YQCGVCGKIFRQNSDLVNHRRSHT-GEKPYKCNECGKSFSQSYNLAIHQRIHTGE 327
Score = 75.9 bits (185), Expect = 3e-13
Identities = 73/319 (22%), Positives = 111/319 (34%), Gaps = 52/319 (16%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C++C + F L+RHR++ + +PY+C CG+ Y SL H
Sbjct: 640 CNECGKVFSYYSCLARHRKI------------HTGEKPYKCNDCGKAYTQRSSLTKHLII 687
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHLQGETVSTDSW 127
H TG P C G F L + R P G + H+ H+ G T
Sbjct: 688 H-TGEKPYNCNEFGGAFIQSSKLARYHRN--PTGEKPHKCSHCGRTFSHITGLTY----- 739
Query: 128 GQRLGSSEGWENQTKHTEETP----DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDG 183
+Q +HT E P +C V + + + T ++ + G
Sbjct: 740 -----------HQRRHTGEMPYKCIECGQVFNSTSNLARHRRIHTGEKPYKCNECGKVFR 788
Query: 184 ADGWGPSTNSARAPPLPIPASSL--LSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKC 241
S P + + L TG ++ YKC
Sbjct: 789 HQSTLARHRSIHTGEKPYVCNECGKAFRVRSILVNHQKMHTG------------DKPYKC 836
Query: 242 SQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCP 300
++CGK + L H+++HT Y C C K F L H +H+ +PY C C
Sbjct: 837 NECGKAFIERSKLVYHQRNHTGEKPYKCIECGKAFGRFSCLNKHQMIHSGEKPYKCNECG 896
Query: 301 RVFRLPRELLEHQQSHEGE 319
+ F L +HQ H E
Sbjct: 897 KSFISRSGLTKHQTKHTAE 915
Score = 51.2 bits (121), Expect = 9e-06
Identities = 30/96 (31%), Positives = 42/96 (43%), Gaps = 15/96 (15%)
Query: 9 SCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRR 68
+C C + F +L+RH + + + +PY+C +CG+ + LV HRR
Sbjct: 443 TCDVCDKVFSQRSQLARH------------QRSHTGEKPYKCNECGKVFSQTSHLVGHRR 490
Query: 69 THETGLFP--CTTCGKDFSNPMALKSHMRTHAPEGR 102
H TG P C CGK F L H H E R
Sbjct: 491 IH-TGEKPYKCDKCGKAFKQGSLLTRHKIIHTREKR 525
Score = 50.4 bits (119), Expect = 2e-05
Identities = 25/93 (26%), Positives = 39/93 (41%), Gaps = 2/93 (2%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C++CGK + + L+ H N T + C+ C K F H H + + C +C
Sbjct: 836 CNECGKAFIERSKLVYHQRNHTGEKPYKCIECGKAFGRFSCLNKHQMIHSGEKPYKCNEC 895
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARD 1623
GK+F S L H H + +E+ D
Sbjct: 896 GKSFISRSGLTKHQTKHTAESLKTKFNVEKPLD 928
Score = 47.8 bits (112), Expect = 1e-04
Identities = 30/91 (32%), Positives = 41/91 (45%), Gaps = 4/91 (4%)
Query: 11 SDCQRHFPSLP-ELSR--HRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHR 67
S QR PS+ +S+ E L S E+ +PY C+ CG+ +R SL+NH+
Sbjct: 178 SPLQRILPSVQTNISKKYENEFLQLSLPTQLEKTHIREKPYMCKGCGKAFRVSSSLINHQ 237
Query: 68 RTHETGL-FPCTTCGKDFSNPMALKSHMRTH 97
H T + C CGK F L H H
Sbjct: 238 MVHTTEKPYKCNECGKAFHRGSLLTIHQIVH 268
Score = 47.8 bits (112), Expect = 1e-04
Identities = 41/158 (25%), Positives = 63/158 (39%), Gaps = 41/158 (25%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQ-----------------DSEEADSIPRPYRCQQ 52
C++C + F L+RHR + H + ++ + +PY+C +
Sbjct: 780 CNECGKVFRHQSTLARHRSI-HTGEKPYVCNECGKAFRVRSILVNHQKMHTGDKPYKCNE 838
Query: 53 CGRGYRHPGSLVNHRRTHETGLFP--CTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRP 110
CG+ + LV H+R H TG P C CGK F L H H+ E +P +
Sbjct: 839 CGKAFIERSKLVYHQRNH-TGEKPYKCIECGKAFGRFSCLNKHQMIHSGE-----KPYKC 892
Query: 111 KEATPHLQGETVSTDSWGQRLGSSEG-WENQTKHTEET 147
E G+ S G ++QTKHT E+
Sbjct: 893 NEC--------------GKSFISRSGLTKHQTKHTAES 916
Score = 45.1 bits (105), Expect = 6e-04
Identities = 23/60 (38%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
Query: 1724 RTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQH 1783
+TH K + C CGKAFR ++ L H VH E P+ C C + F R HQ H
Sbjct: 210 KTHIREKPYMCKGCGKAFRVSSSLINHQMVHT-TEKPYKCNECGKAFHRGSLLTIHQIVH 268
Score = 45.1 bits (105), Expect = 6e-04
Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 13/92 (14%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C C + F L H +++H + +PY+C +CG+ + L H+
Sbjct: 220 CKGCGKAFRVSSSLINH-QMVHTTE-----------KPYKCNECGKAFHRGSLLTIHQIV 267
Query: 70 HETGL-FPCTTCGKDFSNPMALKSHMRTHAPE 100
H G + C CGK F L +H R+H E
Sbjct: 268 HTRGKPYQCGVCGKIFRQNSDLVNHRRSHTGE 299
Score = 42.0 bits (97), Expect = 0.005
Identities = 26/97 (26%), Positives = 44/97 (45%), Gaps = 6/97 (6%)
Query: 821 HTCSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQ 879
+ C++CG +F + L+ H+ H Y+C C K F L H H + +
Sbjct: 834 YKCNECGKAFIERSKLVYHQRNHTGEKPYKCIECGKAFGRFSCLNKHQMIH-----SGEK 888
Query: 880 PFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEE 916
P+ C CG F R+G H+ + + S T+ + E+
Sbjct: 889 PYKCNECGKSFISRSGLTKHQTKHTAESLKTKFNVEK 925
>gi|222831664 zinc finger protein 184 [Homo sapiens]
Length = 751
Score = 203 bits (516), Expect = 1e-51
Identities = 151/602 (25%), Positives = 241/602 (40%), Gaps = 106/602 (17%)
Query: 1194 QTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRI 1251
Q + E+P+ C C +++ + +LINH++ H TG + C C KGF SL H+RI
Sbjct: 241 QRTHTGEKPYKCNECEKAFSRSENLINHQRIH-TGDKPYKCDQCGKGFIEGPSLTQHQRI 299
Query: 1252 HADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHA 1311
H + ++C ECGKAF R L HQR+H ++P+ C +CG+ +
Sbjct: 300 HTGEKPYKCDECGKAFSQRTHLVQHQRIH-------------TGEKPYTCNECGKAFSQR 346
Query: 1312 GSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALC 1369
G + H++ H TG+ + C C KT++ L HQ++H+ + +C C
Sbjct: 347 GHFMEHQKIH-TGEKPFKCDECDKTFTRSTHLTQHQKIHTGEK----------TYKCNEC 395
Query: 1370 GRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHL 1429
G++F G + RH H + N G + +NLT Q T G +P
Sbjct: 396 GKAFNGPSTFIRHHMIHTGEKPYECNECG---KAFSQHSNLTQHQKTHT---GEKPYDCA 449
Query: 1430 EDGVPRPGERSQSP-IRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEE 1488
E G S + ++ + E P N G + ++
Sbjct: 450 ECGKSFSYWSSLAQHLKIHTGEKPYKC-----------------NECGKAFSYCSSLTQH 492
Query: 1489 PEDSVHRSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHSSCSQCGKTYCQSGSLLN 1548
P +C G S++ + N+ + Q ++ C +CGK + +S SL
Sbjct: 493 RRIHTREKPFECSEC---GKAFSYLSNL-NQHQKTHTQEKAY-ECKECGKAFIRSSSLAK 547
Query: 1549 HNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQA 1606
H T + C C K F + H H + + C +CG+AF + L H +
Sbjct: 548 HERIHTGEKPYQCHECGKTFSYGSSLIQHRKIHTGERPYKCNECGRAFNQNIHLTQHKRI 607
Query: 1607 HARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVERARGGQAVT 1666
H T P E E + + +
Sbjct: 608 H----------------------------------------TGAKPYECAECGKAFRHCS 627
Query: 1667 SMAAEDK----ERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLCPKLLPNLLSLKN 1721
S+A K E+P++C +C +++ + L HQ+ HT Y C+ C K L
Sbjct: 628 SLAQHQKTHTEEKPYQCNKCEKTFSQSSHLTQHQRIHTGEKPYKCNECDKAFSRSTHLTE 687
Query: 1722 HSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQ 1781
H THT K + C+ C K F + L H R+H+ E PF C C + FR R + +HQ+
Sbjct: 688 HQNTHTGEKPYNCNECRKTFSQSTYLIQHQRIHS-GEKPFGCNDCGKSFRYRSALNKHQR 746
Query: 1782 QH 1783
H
Sbjct: 747 LH 748
Score = 191 bits (484), Expect = 7e-48
Identities = 152/566 (26%), Positives = 215/566 (37%), Gaps = 77/566 (13%)
Query: 1232 CQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRK 1291
C C K FS +L H+R H + ++C+EC KAF + L +HQR+H
Sbjct: 224 CNECGKAFSYCSALIRHQRTHTGEKPYKCNECEKAFSRSENLINHQRIHTG--------- 274
Query: 1292 ATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHS 1349
D+P++C QCG+ + SL H+R H TG+ Y C C K +S R L HQR+H+
Sbjct: 275 ----DKPYKCDQCGKGFIEGPSLTQHQRIH-TGEKPYKCDECGKAFSQRTHLVQHQRIHT 329
Query: 1350 ENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASEAN 1409
+ C CG++F RG H + H T +P D T +
Sbjct: 330 GEK----------PYTCNECGKAFSQRGHFMEHQKIH--TGEKPFKCDE-CDKTFTRSTH 376
Query: 1410 LTGSQGLETQLGGAEPVPHLEDGVPRPGERSQSPIRAA-SSEAPEPLSWGAGKAGGWPVG 1468
LT Q + T G + E G G + + E P + G
Sbjct: 377 LTQHQKIHT---GEKTYKCNECGKAFNGPSTFIRHHMIHTGEKPYECN---------ECG 424
Query: 1469 GGLGNHSGGWVPQFLTRSEEPEDSVHRSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPG 1528
HS Q E+P D C G + S+ W + ++ G
Sbjct: 425 KAFSQHSNLTQHQKTHTGEKPYD-----------CAECGKSFSY---WSSLAQHLKIHTG 470
Query: 1529 SHS-SCSQCGKTYCQSGSLLNHNTNKTDRH--YCLLCSKEFLNPVATKSHSHNHIDAQTF 1585
C++CGK + SL H T C C K F H H + +
Sbjct: 471 EKPYKCNECGKAFSYCSSLTQHRRIHTREKPFECSECGKAFSYLSNLNQHQKTHTQEKAY 530
Query: 1586 ACPDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAP 1645
C +CGKAF LA H + H + P Q E + G Q
Sbjct: 531 ECKECGKAFIRSSSLAKHERIHT---GEKPYQCHEC---------GKTFSYGSSLIQHRK 578
Query: 1646 SETPRGPGESVERARGGQAVTSMAAEDK----ERPFRCTQCGRSYRHAGSLLNHQKAHTT 1701
T P + E R + + +P+ C +CG+++RH SL HQK HT
Sbjct: 579 IHTGERPYKCNECGRAFNQNIHLTQHKRIHTGAKPYECAECGKAFRHCSSLAQHQKTHTE 638
Query: 1702 GL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGP 1760
Y C+ C K L H R HT K + C+ C KAF + L H H E P
Sbjct: 639 EKPYQCNKCEKTFSQSSHLTQHQRIHTGEKPYKCNECDKAFSRSTHLTEHQNTHTG-EKP 697
Query: 1761 FTCPHCPRHFRRRISFVQHQQQHQEE 1786
+ C C + F + +QHQ+ H E
Sbjct: 698 YNCNECRKTFSQSTYLIQHQRIHSGE 723
Score = 167 bits (423), Expect = 9e-41
Identities = 173/693 (24%), Positives = 261/693 (37%), Gaps = 140/693 (20%)
Query: 2 EDTPPSLSCSDCQRHFPSLPELSRHRELLHPSPNQDSEEA----DSIP----RPYRCQQC 53
E T PS F +S + PSP + S + +S P + +C +C
Sbjct: 168 EKTIPSWEKGPVNNEFGKSVNVSSNLVTQEPSPEETSTKRSIKQNSNPVKKEKSCKCNEC 227
Query: 54 GRGYRHPGSLVNHRRTHETGLFP--CTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPK 111
G+ + + +L+ H+RTH TG P C C K FS L +H +R H +P
Sbjct: 228 GKAFSYCSALIRHQRTH-TGEKPYKCNECEKAFSRSENLINH--------QRIHTGDKPY 278
Query: 112 EATPHLQGETVSTDSWGQRLGSSEG---WENQTKHTEETP-DCESVPDPRAASGTWEDLP 167
+ D G+ G EG ++Q HT E P C+ +A S
Sbjct: 279 KC-----------DQCGK--GFIEGPSLTQHQRIHTGEKPYKCDECG--KAFS------- 316
Query: 168 TRQREGLASHPGPEDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEP 227
QR L H G P S ++ ++ TG
Sbjct: 317 --QRTHLVQHQRIHTG-----------EKPYTCNECGKAFSQRGHFMEHQKIH-TG---- 358
Query: 228 TQSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSR 286
E+ +KC +C KT+ + LT H++ HT Y C C K F+ H
Sbjct: 359 --------EKPFKCDECDKTFTRSTHLTQHQKIHTGEKTYKCNECGKAFNGPSTFIRHHM 410
Query: 287 LHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLP 346
+H +PY C C + F L +HQ++H GE+ P +S
Sbjct: 411 IHTGEKPYECNECGKAFSQHSNLTQHQKTHTGEK----------PYDCAECGKSFSYWSS 460
Query: 347 SAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSH-QTGVYPCSL 405
AQ L +GE +P++C +CG+ + + SL HR+ H + + CS
Sbjct: 461 LAQHLK-----IHTGE---------KPYKCNECGKAFSYCSSLTQHRRIHTREKPFECSE 506
Query: 406 CSKQLFNAAALKNHVRAHHRPRQ-GVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRP 464
C K + L H + H + + E G+ + + L E H E +P
Sbjct: 507 CGKAFSYLSNLNQHQKTHTQEKAYECKECGKAFIRSSSLAKHERIHTGE---------KP 557
Query: 465 YKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHCKAAR-RS 521
Y+C ECG+ + + SL+ HR H TGE Y+C+ C R + + L H R+H A
Sbjct: 558 YQCHECGKTFSYGSSLIQHRKIH-TGERPYKCNECGRAFNQNIHLTQHKRIHTGAKPYEC 616
Query: 522 ADIG-----AEGAPSHLKVELPPDPVEAEAAPHT--DQDHVCKHEEEATDITPAADKTAA 574
A+ G H K P + T H+ +H+ T P
Sbjct: 617 AECGKAFRHCSSLAQHQKTHTEEKPYQCNKCEKTFSQSSHLTQHQRIHTGEKP------- 669
Query: 575 HICSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLIN 634
+ C+ C F + L H TH GEK + C +C K++ S LI
Sbjct: 670 YKCNECDKAFSRSTHLTEHQNTH-TGEKP-------------YNCNECRKTFSQSTYLIQ 715
Query: 635 HRQTHQ-TGDFSCGACAKHFHTMAAMKNHLRRH 666
H++ H F C C K F +A+ H R H
Sbjct: 716 HQRIHSGEKPFGCNDCGKSFRYRSALNKHQRLH 748
Score = 161 bits (408), Expect = 5e-39
Identities = 148/593 (24%), Positives = 236/593 (39%), Gaps = 97/593 (16%)
Query: 823 CSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPF 881
C++CG +F + + L+ H+ H Y+C+ C K F L +H + H T +P+
Sbjct: 224 CNECGKAFSYCSALIRHQRTHTGEKPYKCNECEKAFSRSENLINHQRIH-----TGDKPY 278
Query: 882 LCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELL 941
C CG F H+R H+ + +E G A S+ L
Sbjct: 279 KCDQCGKGFIEGPSLTQHQR-IHTGE-----KPYKCDECGKA-----------FSQRTHL 321
Query: 942 NQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAME 1001
Q QR + + + C CG+ + G H + T +K P
Sbjct: 322 VQHQR----IHTGEKPYTCNECGKAFSQRGHFMEHQKIH----TGEK---PFKCDECDKT 370
Query: 1002 MVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTY 1061
+ L +GE K E G S I+ ++ +P+ CN+CGK +
Sbjct: 371 FTRSTHLTQHQKIHTGEK-TYKCNECGKAFNGPSTFIR--HHMIHTGEKPYECNECGKAF 427
Query: 1062 RHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAAG 1119
+L H+K H TG+ + C C + + ++ HL+ H K + +
Sbjct: 428 SQHSNLTQHQKTH-TGEKPYDCAECGKSFSYWSSLAQHLKIHTGEKPYKCNECGKAFSYC 486
Query: 1120 SSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKE----EVWEET 1175
SS Q I KP +E G + + L + K E+ KE + +
Sbjct: 487 SSLTQHRRIHT--REKPFECSECGKAFSYLSNLNQHQKTHTQEKAYECKECGKAFIRSSS 544
Query: 1176 TVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQ 1233
K E I + E+P+ C CG+++ + SLI HR+ H TG + C
Sbjct: 545 LAKHERIH--------------TGEKPYQCHECGKTFSYGSSLIQHRKIH-TGERPYKCN 589
Query: 1234 ACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKAT 1293
C + F+ + L H+RIH + + C+ECGKAFR LA HQ+ H
Sbjct: 590 ECGRAFNQNIHLTQHKRIHTGAKPYECAECGKAFRHCSSLAQHQKTH------------- 636
Query: 1294 REDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSEN 1351
E++P++C +C +T+ + L H+R H TG+ Y C C K +S L +HQ H+
Sbjct: 637 TEEKPYQCNKCEKTFSQSSHLTQHQRIH-TGEKPYKCNECDKAFSRSTHLTEHQNTHTGE 695
Query: 1352 RRRRAGRSRRTAVR------------------CALCGRSFPGRGSLERHLREH 1386
+ R+T + C CG+SF R +L +H R H
Sbjct: 696 KPYNCNECRKTFSQSTYLIQHQRIHSGEKPFGCNDCGKSFRYRSALNKHQRLH 748
Score = 158 bits (399), Expect = 5e-38
Identities = 140/583 (24%), Positives = 238/583 (40%), Gaps = 108/583 (18%)
Query: 108 PRPKEATPHLQGETV-----STDSWGQRLGSSEGWENQTKHTEETPDCESVPDPRAASGT 162
P P + L E + DSW L E WE + + + +++P + T
Sbjct: 112 PEPDISEEELSPEVIVEKHKRDDSWSSNL--LESWEYEGSLERQQANQQTLP--KEIKVT 167
Query: 163 WEDLPTRQREGLASHPGPEDGADGWGPSTNSARAPPLPIPA-SSLLSNLEQYLAESVVNF 221
+ +P+ ++ GP + G + +S P P +S +++Q
Sbjct: 168 EKTIPSWEK-------GPVNNEFGKSVNVSSNLVTQEPSPEETSTKRSIKQ--------- 211
Query: 222 TGGQEPTQSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMA 280
S P ++E+ KC++CGK + + +L H+++HT Y C C K FS
Sbjct: 212 -------NSNPVKKEKSCKCNECGKAFSYCSALIRHQRTHTGEKPYKCNECEKAFSRSEN 264
Query: 281 LKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDES 340
L NH R+H +PY C C + F L +HQ+ H GE+ + +E G S
Sbjct: 265 LINHQRIHTGDKPYKCDQCGKGFIEGPSLTQHQRIHTGEKPY-KCDECGKAF-------S 316
Query: 341 SQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTGV 400
+ L Q ++ +GE +P+ C +CG+ + G + H+K H TG
Sbjct: 317 QRTHLVQHQRIH-------TGE---------KPYTCNECGKAFSQRGHFMEHQKIH-TGE 359
Query: 401 YP--CSLCSKQLFNAAALKNHVRAHHRPR-QGVGENGQPSVPPAPLLLAETTHKEEEDPT 457
P C C K + L H + H + E G+ P+ + H E
Sbjct: 360 KPFKCDECDKTFTRSTHLTQHQKIHTGEKTYKCNECGKAFNGPSTFIRHHMIHTGE---- 415
Query: 458 TTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVH- 514
+PY+C+ECG+A+ +L H+ +H TGE Y C+ C + + +L H+++H
Sbjct: 416 -----KPYECNECGKAFSQHSNLTQHQKTH-TGEKPYDCAECGKSFSYWSSLAQHLKIHT 469
Query: 515 ------CKAARRSADIGAEGAPSHLKVELPPDPVEAE--AAPHTDQDHVCKHEEEATDIT 566
C ++ H ++ P E + ++ +H++ T
Sbjct: 470 GEKPYKCNECGKAFSY-CSSLTQHRRIHTREKPFECSECGKAFSYLSNLNQHQKTHT--- 525
Query: 567 PAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSY 626
+ A+ C CG F + SL +H H GEK + C +CGK++
Sbjct: 526 ----QEKAYECKECGKAFIRSSSLAKHERIH-TGEK-------------PYQCHECGKTF 567
Query: 627 RHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHS 667
+ SLI HR+ H TG+ + C C + F+ + H R H+
Sbjct: 568 SYGSSLIQHRKIH-TGERPYKCNECGRAFNQNIHLTQHKRIHT 609
Score = 154 bits (389), Expect = 8e-37
Identities = 116/455 (25%), Positives = 180/455 (39%), Gaps = 87/455 (19%)
Query: 236 ERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPY 294
++ YKC QCGK + SLT H++ HT Y C C K FS L H R+H +PY
Sbjct: 275 DKPYKCDQCGKGFIEGPSLTQHQRIHTGEKPYKCDECGKAFSQRTHLVQHQRIHTGEKPY 334
Query: 295 HCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNG---------HTDESSQDQL 345
C C + F +EHQ+ H GE+ + +E T HT E +
Sbjct: 335 TCNECGKAFSQRGHFMEHQKIHTGEKPF-KCDECDKTFTRSTHLTQHQKIHTGEKTYKCN 393
Query: 346 PSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPC 403
+ NG + + +P+ C +CG+ + +L H+K+H TG Y C
Sbjct: 394 ECGKAFNGPSTFIRHHMIHTG----EKPYECNECGKAFSQHSNLTQHQKTH-TGEKPYDC 448
Query: 404 SLCSKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHR 463
+ C K ++L H++ H GE +
Sbjct: 449 AECGKSFSYWSSLAQHLKIH------TGE------------------------------K 472
Query: 464 PYKCSECGRAYRHRGSLVNHRHSH-RTGEYQCSLCPRKYPNLMALRNHVRVH-------C 515
PYKC+ECG+A+ + SL HR H R ++CS C + + L L H + H C
Sbjct: 473 PYKCNECGKAFSYCSSLTQHRRIHTREKPFECSECGKAFSYLSNLNQHQKTHTQEKAYEC 532
Query: 516 KAARRSADIGAEGAPSHLKVELPPDPVEAEAAPHTDQ--DHVCKHEEEATDITPAADKTA 573
K + A I + H ++ P + T + +H + T P
Sbjct: 533 KECGK-AFIRSSSLAKHERIHTGEKPYQCHECGKTFSYGSSLIQHRKIHTGERP------ 585
Query: 574 AHICSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLI 633
+ C+ CG F L +H H + + + C +CGK++RH SL
Sbjct: 586 -YKCNECGRAFNQNIHLTQHKRIH--------------TGAKPYECAECGKAFRHCSSLA 630
Query: 634 NHRQTH-QTGDFSCGACAKHFHTMAAMKNHLRRHS 667
H++TH + + C C K F + + H R H+
Sbjct: 631 QHQKTHTEEKPYQCNKCEKTFSQSSHLTQHQRIHT 665
Score = 144 bits (362), Expect = 1e-33
Identities = 116/416 (27%), Positives = 183/416 (43%), Gaps = 73/416 (17%)
Query: 1050 RPFRCNQCGKTYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCK-G 1106
+P++C+QCGK + G SL H++IH TG+ + C C + + + R HL H R G
Sbjct: 276 KPYKCDQCGKGFIEGPSLTQHQRIH-TGEKPYKCDECGKAF----SQRTHLVQHQRIHTG 330
Query: 1107 SEPQVGPIPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEK-------LQEELKVE 1159
+P G + Q G E ++ H E+ E +K L + K+
Sbjct: 331 EKPYTC---NECGKAFSQRGHFME---HQKIHTGEKPFKCDECDKTFTRSTHLTQHQKIH 384
Query: 1160 PLEEVARVKE----EVWEETTVKGEEI---EPRLETAEKGC-----------QTEASSER 1201
E+ + E T ++ I E E E G Q + E+
Sbjct: 385 TGEKTYKCNECGKAFNGPSTFIRHHMIHTGEKPYECNECGKAFSQHSNLTQHQKTHTGEK 444
Query: 1202 PFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPRRFR 1259
P+ C CG+S+ + SL H + H TG + C C K FS SL HRRIH + F
Sbjct: 445 PYDCAECGKSFSYWSSLAQHLKIH-TGEKPYKCNECGKAFSYCSSLTQHRRIHTREKPFE 503
Query: 1260 CSECGKAFRLRKQLASHQRVHMERR-------GGGGTRKAT--------REDRPFRCGQC 1304
CSECGKAF L HQ+ H + + G R ++ ++P++C +C
Sbjct: 504 CSECGKAFSYLSNLNQHQKTHTQEKAYECKECGKAFIRSSSLAKHERIHTGEKPYQCHEC 563
Query: 1305 GRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRT 1362
G+T+ + SL+ HR+ H TG+ Y C C + ++ + L H+R+H+ +
Sbjct: 564 GKTFSYGSSLIQHRKIH-TGERPYKCNECGRAFNQNIHLTQHKRIHTGAK---------- 612
Query: 1363 AVRCALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASEANLTGSQGLET 1418
CA CG++F SL +H + H E + N + T + ++LT Q + T
Sbjct: 613 PYECAECGKAFRHCSSLAQHQKTHTEEKPYQCN---KCEKTFSQSSHLTQHQRIHT 665
Score = 111 bits (278), Expect = 6e-24
Identities = 84/319 (26%), Positives = 126/319 (39%), Gaps = 52/319 (16%)
Query: 1519 RDNSSQLQPGSHSSCSQCGK--TYC--------------------------QSGSLLNHN 1550
+ NS+ ++ C++CGK +YC +S +L+NH
Sbjct: 210 KQNSNPVKKEKSCKCNECGKAFSYCSALIRHQRTHTGEKPYKCNECEKAFSRSENLINHQ 269
Query: 1551 TNKT-DRHY-CLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHA 1608
T D+ Y C C K F+ + H H + + C +CGKAF L H + H
Sbjct: 270 RIHTGDKPYKCDQCGKGFIEGPSLTQHQRIHTGEKPYKCDECGKAFSQRTHLVQHQRIHT 329
Query: 1609 RGHSQVPAQMEEARDPKAGTGEDQVVLPGQG--KAQEAPSETPRG----------PGESV 1656
+ +A + E Q + G+ K E R GE
Sbjct: 330 GEKPYTCNECGKAFSQRGHFMEHQKIHTGEKPFKCDECDKTFTRSTHLTQHQKIHTGEKT 389
Query: 1657 ERARG-GQAVTSMAA-------EDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCS 1707
+ G+A + E+P+ C +CG+++ +L HQK HT Y C+
Sbjct: 390 YKCNECGKAFNGPSTFIRHHMIHTGEKPYECNECGKAFSQHSNLTQHQKTHTGEKPYDCA 449
Query: 1708 LCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCP 1767
C K SL H + HT K + C+ CGKAF + L H R+H RE PF C C
Sbjct: 450 ECGKSFSYWSSLAQHLKIHTGEKPYKCNECGKAFSYCSSLTQHRRIHT-REKPFECSECG 508
Query: 1768 RHFRRRISFVQHQQQHQEE 1786
+ F + QHQ+ H +E
Sbjct: 509 KAFSYLSNLNQHQKTHTQE 527
Score = 106 bits (265), Expect = 2e-22
Identities = 80/313 (25%), Positives = 131/313 (41%), Gaps = 44/313 (14%)
Query: 372 RPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFNAAALKNHVRAHHRPRQG 429
+P++C +C + + + +LINH++ H TG Y C C K +L H R H
Sbjct: 248 KPYKCNECEKAFSRSENLINHQRIH-TGDKPYKCDQCGKGFIEGPSLTQHQRIH------ 300
Query: 430 VGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRT 489
GE ++ TH + T +PY C+ECG+A+ RG + H+ H T
Sbjct: 301 TGEKPY-KCDECGKAFSQRTHLVQHQRIHT-GEKPYTCNECGKAFSQRGHFMEHQKIH-T 357
Query: 490 GE--YQCSLCPRKYPNLMALRNHVRVHC--KAARRSADIGAEGAPS----HLKVELPPDP 541
GE ++C C + + L H ++H K + + A PS H + P
Sbjct: 358 GEKPFKCDECDKTFTRSTHLTQHQKIHTGEKTYKCNECGKAFNGPSTFIRHHMIHTGEKP 417
Query: 542 VEAEAAPHTDQDH--VCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGA 599
E H + +H++ T P + C+ CG F SL +H H
Sbjct: 418 YECNECGKAFSQHSNLTQHQKTHTGEKP-------YDCAECGKSFSYWSSLAQHLKIH-T 469
Query: 600 GEKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTH-QTGDFSCGACAKHFHTMAA 658
GEK + C +CGK++ + SL HR+ H + F C C K F ++
Sbjct: 470 GEKP-------------YKCNECGKAFSYCSSLTQHRRIHTREKPFECSECGKAFSYLSN 516
Query: 659 MKNHLRRHSRRRS 671
+ H + H++ ++
Sbjct: 517 LNQHQKTHTQEKA 529
Score = 104 bits (260), Expect = 7e-22
Identities = 99/400 (24%), Positives = 165/400 (41%), Gaps = 88/400 (22%)
Query: 310 LEHQQSHEG---------ERQEPRWEEKGMPTTNGHTDESSQD---QLPSAQMLNGSAEL 357
LE QQ+++ E+ P WE+ + G + S + Q PS + E
Sbjct: 150 LERQQANQQTLPKEIKVTEKTIPSWEKGPVNNEFGKSVNVSSNLVTQEPSPE------ET 203
Query: 358 STSGELEDSG--LEEYRPFRCGDCGRTYRHAGSLINHRKSHQTGV--YPCSLCSKQLFNA 413
ST ++ + +++ + +C +CG+ + + +LI H+++H TG Y C+ C K +
Sbjct: 204 STKRSIKQNSNPVKKEKSCKCNECGKAFSYCSALIRHQRTH-TGEKPYKCNECEKAFSRS 262
Query: 414 AALKNHVRAHHRPRQ-GVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGR 472
L NH R H + + G+ + L + H E +PYKC ECG+
Sbjct: 263 ENLINHQRIHTGDKPYKCDQCGKGFIEGPSLTQHQRIHTGE---------KPYKCDECGK 313
Query: 473 AYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHCKAARRSADIGAEGAP 530
A+ R LV H+ H TGE Y C+ C + + H ++H D
Sbjct: 314 AFSQRTHLVQHQRIH-TGEKPYTCNECGKAFSQRGHFMEHQKIHTGEKPFKCD------- 365
Query: 531 SHLKVELPPDPVEAEAAPHTDQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESL 590
E + T H+ +H++ T +KT + C+ CG F +
Sbjct: 366 ------------ECDKT-FTRSTHLTQHQKIHT-----GEKT--YKCNECGKAFNGPSTF 405
Query: 591 ERHGLTHGAGEK------------------ENSRTETTMSPPRAFACRDCGKSYRHSGSL 632
RH + H GEK ++ +T T P + C +CGKS+ + SL
Sbjct: 406 IRHHMIH-TGEKPYECNECGKAFSQHSNLTQHQKTHTGEKP---YDCAECGKSFSYWSSL 461
Query: 633 INHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHSRRR 670
H + H TG+ + C C K F +++ H R H+R +
Sbjct: 462 AQHLKIH-TGEKPYKCNECGKAFSYCSSLTQHRRIHTREK 500
Score = 89.4 bits (220), Expect = 3e-17
Identities = 81/320 (25%), Positives = 125/320 (39%), Gaps = 56/320 (17%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C++C + F L++HR + + +P+ C +CG+ + + +L H++T
Sbjct: 476 CNECGKAFSYCSSLTQHRRI------------HTREKPFECSECGKAFSYLSNLNQHQKT 523
Query: 70 H-ETGLFPCTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHLQGETVSTDSWG 128
H + + C CGK F +L H R H E P+ E T S+G
Sbjct: 524 HTQEKAYECKECGKAFIRSSSLAKHERIHTGE-------------KPYQCHECGKTFSYG 570
Query: 129 QRLGSSEGWENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGADGW 187
L +++ HT E P C RA + Q L H GA +
Sbjct: 571 SSL-----IQHRKIHTGERPYKCNECG--RAFN---------QNIHLTQHKRIHTGAKPY 614
Query: 188 GPSTNSARAPPLPIPASSLLSNLEQYLAESVVN-------FTGGQEPTQSPPAEE-ERRY 239
A SSL + + + E F+ TQ E+ Y
Sbjct: 615 ----ECAECGKAFRHCSSLAQHQKTHTEEKPYQCNKCEKTFSQSSHLTQHQRIHTGEKPY 670
Query: 240 KCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPH 298
KC++C K + + LT H+ +HT Y C C K FS L H R+H+ +P+ C
Sbjct: 671 KCNECDKAFSRSTHLTEHQNTHTGEKPYNCNECRKTFSQSTYLIQHQRIHSGEKPFGCND 730
Query: 299 CPRVFRLPRELLEHQQSHEG 318
C + FR L +HQ+ H G
Sbjct: 731 CGKSFRYRSALNKHQRLHPG 750
Score = 84.7 bits (208), Expect = 7e-16
Identities = 123/580 (21%), Positives = 206/580 (35%), Gaps = 108/580 (18%)
Query: 577 CSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHR 636
C+ CG F +L RH TH GEK + C +C K++ S +LINH+
Sbjct: 224 CNECGKAFSYCSALIRHQRTH-TGEKP-------------YKCNECEKAFSRSENLINHQ 269
Query: 637 QTHQTGD--FSCGACAKHFHTMAAMKNHLRRHSRRR------------SRRHRKRAGGAS 682
+ H TGD + C C K F ++ H R H+ + R H +
Sbjct: 270 RIH-TGDKPYKCDQCGKGFIEGPSLTQHQRIHTGEKPYKCDECGKAFSQRTHLVQHQRIH 328
Query: 683 GGREAKLLAAESWTRELEDNEGLESPQDPSGESPHGAEGNLESDGDCLQAESEGDKCGLE 742
G E E + +E + +GE P + +C + + L
Sbjct: 329 TG-EKPYTCNECGKAFSQRGHFMEHQKIHTGEKPFKCD-------ECDKTFTRSTH--LT 378
Query: 743 RDETHFQGDK--ESGGTGEGLERKDASLLDNLDIPGEEGGGTHFCDSL----TGVDEDQK 796
+ + G+K + G+ + ++ GE+ + C + + + QK
Sbjct: 379 QHQKIHTGEKTYKCNECGKAFNGPSTFIRHHMIHTGEKPYECNECGKAFSQHSNLTQHQK 438
Query: 797 PATGQ-PNSSSHSANAVTGWQAGAAHT----------CSDCGHSFPHATGLLSHRPCHP- 844
TG+ P + + + W + A H C++CG +F + + L HR H
Sbjct: 439 THTGEKPYDCAECGKSFSYWSSLAQHLKIHTGEKPYKCNECGKAFSYCSSLTQHRRIHTR 498
Query: 845 PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIF-------------P 891
++CS C K F L L H + H T + + C CG F
Sbjct: 499 EKPFECSECGKAFSYLSNLNQHQKTH-----TQEKAYECKECGKAFIRSSSLAKHERIHT 553
Query: 892 GRAGYRLH---RRQAHSSSGMTEGSEEEGEEE-GVAEAAPARSPPLQLSEAELLNQLQRE 947
G Y+ H + ++ SS + GE E A + + L++ + ++ +
Sbjct: 554 GEKPYQCHECGKTFSYGSSLIQHRKIHTGERPYKCNECGRAFNQNIHLTQHKRIHTGAKP 613
Query: 948 VEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSV 1007
E C CG+ + SL +H + T ++ P S
Sbjct: 614 YE----------CAECGKAFRHCSSLAQHQK-----THTEEKPYQCNKCEKTFSQ--SSH 656
Query: 1008 LEDIVNSVSGEG----GDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYRH 1063
L +GE + T L + GE +P+ CN+C KT+
Sbjct: 657 LTQHQRIHTGEKPYKCNECDKAFSRSTHLTEHQNTHTGE-------KPYNCNECRKTFSQ 709
Query: 1064 GGSLVNHRKIHQ-TGDFLCPVCSRCYPNLAAYRNHLRNHP 1102
L+ H++IH F C C + + +A H R HP
Sbjct: 710 STYLIQHQRIHSGEKPFGCNDCGKSFRYRSALNKHQRLHP 749
Score = 84.7 bits (208), Expect = 7e-16
Identities = 42/116 (36%), Positives = 55/116 (47%), Gaps = 2/116 (1%)
Query: 1674 ERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRH 1732
++P++C QCG+ + SL HQ+ HT Y C C K L H R HT K +
Sbjct: 275 DKPYKCDQCGKGFIEGPSLTQHQRIHTGEKPYKCDECGKAFSQRTHLVQHQRIHTGEKPY 334
Query: 1733 CCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEEWT 1788
C+ CGKAF H ++H E PF C C + F R QHQ+ H E T
Sbjct: 335 TCNECGKAFSQRGHFMEHQKIHT-GEKPFKCDECDKTFTRSTHLTQHQKIHTGEKT 389
Score = 43.5 bits (101), Expect = 0.002
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 1/66 (1%)
Query: 1718 SLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFV 1777
S+K +S K C+ CGKAF + L H R H E P+ C C + F R + +
Sbjct: 208 SIKQNSNPVKKEKSCKCNECGKAFSYCSALIRHQRTHT-GEKPYKCNECEKAFSRSENLI 266
Query: 1778 QHQQQH 1783
HQ+ H
Sbjct: 267 NHQRIH 272
>gi|239747149 PREDICTED: hypothetical protein XP_002343926 isoform 2
[Homo sapiens]
Length = 738
Score = 196 bits (499), Expect = 1e-49
Identities = 160/612 (26%), Positives = 234/612 (38%), Gaps = 110/612 (17%)
Query: 1200 ERPFSCEVCGRSYKHAGSLINHRQSH-QTGHFGCQACSKGFSNLMSLKNHRRIHADPRRF 1258
E+ + C C + + SLI H+ H + FGC C K F H R H + +
Sbjct: 204 EKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPY 263
Query: 1259 RCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHR 1318
CS+CGKAF + QL SHQR H ++P+ CG+CG+ + L++H
Sbjct: 264 NCSQCGKAFSQKSQLTSHQRTH-------------TGEKPYECGECGKAFSRKSHLISHW 310
Query: 1319 RSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGR 1376
R+H TG+ Y C C + +S + L +HQR+H+ + C CG++F +
Sbjct: 311 RTH-TGEKPYGCNECGRAFSEKSNLINHQRIHTGEK----------PFECRECGKAFSRK 359
Query: 1377 GSLERHLREHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRP 1436
L H R H T+ G ++ L Q + T G +P E R
Sbjct: 360 SQLVTHHRTHTGTK---PFGCSDCRKAFFEKSELIRHQTIHT---GEKP---YECSECRK 410
Query: 1437 GERSQSPI----RAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEP--- 1489
R +S + R + E P G G S Q E+P
Sbjct: 411 AFRERSSLINHQRTHTGEKPH---------GCIQCGKAFSQKSHLISHQMTHTGEKPFIC 461
Query: 1490 ----------EDSVHRSPCHAG----DCQLNGPTLSHMDSWDNRDN-SSQLQPGSHSSCS 1534
V H G +C G S S N + +P S C
Sbjct: 462 SKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSEC- 520
Query: 1535 QCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGK 1592
GK +CQ L++H T + C C K F + +H H + + C DC K
Sbjct: 521 --GKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEK 578
Query: 1593 AFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGP 1652
AF +L +H + H TGE KA SE
Sbjct: 579 AFSQKSQLNTHQRIH--------------------TGEKPYECSLCRKAFFEKSE----- 613
Query: 1653 GESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLCPK 1711
+ + E+P+ C +C +++R SL+NHQ+ HT + CS C K
Sbjct: 614 -----------LIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGK 662
Query: 1712 LLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFR 1771
L H RTHT K + CS C KAF ++L H R+H E P+ C C + F
Sbjct: 663 AFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHT-GEKPYRCIECGKAFS 721
Query: 1772 RRISFVQHQQQH 1783
++ + HQ+ H
Sbjct: 722 QKSQLINHQRTH 733
Score = 169 bits (429), Expect = 2e-41
Identities = 166/670 (24%), Positives = 256/670 (38%), Gaps = 125/670 (18%)
Query: 30 LHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRTHETGLFPCTTCGKDFSNPMA 89
LH P E+ D+ + Y C + Y+ ++ HR L+ C+ C K FS
Sbjct: 166 LHSKP----EDTDTWLKYYDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSK--- 218
Query: 90 LKSHMRTHAPEGRRRHRPPRPKEATPHLQGETVSTDSWGQRLGS-SEGWENQTKHTEETP 148
+P K + H++ + G+ S+ + HT E P
Sbjct: 219 ----------------KPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKP 262
Query: 149 -DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGADGWGPSTNSARAPPLPIPASSLL 207
+C +A S Q+ L SH G P
Sbjct: 263 YNCSQCG--KAFS---------QKSQLTSHQRTHTGEK------------PYECGECGKA 299
Query: 208 SNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSHTLGIYP 267
+ + +L TG E+ Y C++CG+ + +L NH++ HT G P
Sbjct: 300 FSRKSHLISHWRTHTG------------EKPYGCNECGRAFSEKSNLINHQRIHT-GEKP 346
Query: 268 --CAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGE------ 319
C C K FS L H R H +P+ C C + F EL+ HQ H GE
Sbjct: 347 FECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECS 406
Query: 320 --RQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCG 377
R+ R + HT E + + + + L S ++ +G +PF C
Sbjct: 407 ECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHL-ISHQMTHTG---EKPFICS 462
Query: 378 DCGRTYRHAGSLINHRKSHQTGV--YPCSLCSKQLFNAAALKNHVRAHHRPRQGV-GENG 434
CG+ + L+ H+++H TG Y CS C K +L NH R H + V E G
Sbjct: 463 KCGKAFSRKSQLVRHQRTH-TGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECG 521
Query: 435 QPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--Y 492
+ + L+ + TH E +PY+CSECG+A+ + SL H+ +H TGE Y
Sbjct: 522 KAFCQKSHLISHQRTHTGE---------KPYECSECGKAFGEKSSLATHQRTH-TGEKPY 571
Query: 493 QCSLCPRKYPNLMALRNHVRVH-------CKAARRSADIGAEGAPSHLKVELPPDPVEAE 545
+C C + + L H R+H C R++ +E HL+ P E
Sbjct: 572 ECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSE-LIRHLRTHTGEKPYECN 630
Query: 546 AAPHT--DQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKE 603
++ + H+ T P CS CG F L H TH GEK
Sbjct: 631 ECRKAFREKSSLINHQRIHTGEKPFE-------CSECGKAFSRKSHLIPHQRTH-TGEKP 682
Query: 604 NSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKN 661
+ C +C K++ L+NH++ H TG+ + C C K F + + N
Sbjct: 683 -------------YGCSECRKAFSQKSQLVNHQRIH-TGEKPYRCIECGKAFSQKSQLIN 728
Query: 662 HLRRHSRRRS 671
H R H+ ++S
Sbjct: 729 HQRTHTVKKS 738
Score = 164 bits (414), Expect = 1e-39
Identities = 156/577 (27%), Positives = 230/577 (39%), Gaps = 124/577 (21%)
Query: 10 CSDCQRHFPSLPELSRHREL--------------LHPSPNQ--DSEEADSIPRPYRCQQC 53
CS+C++ F P L +H+ P +Q + +PY C QC
Sbjct: 209 CSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQC 268
Query: 54 GRGYRHPGSLVNHRRTHETGLFP--CTTCGKDFSNPMALKSHMRTHAPE--------GR- 102
G+ + L +H+RTH TG P C CGK FS L SH RTH E GR
Sbjct: 269 GKAFSQKSQLTSHQRTH-TGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRA 327
Query: 103 -----------RRHRPPRPKEA-------------TPHLQGETVS-----TDSWGQRLGS 133
R H +P E H + T + +D
Sbjct: 328 FSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEK 387
Query: 134 SEGWENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGADGWGPSTN 192
SE +QT HT E P +C + R A R+R L +H T+
Sbjct: 388 SELIRHQTIHTGEKPYECS---ECRKA--------FRERSSLINH-----------QRTH 425
Query: 193 SARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGKTYKHAG 252
+ P I S + +L + TG E+ + CS+CGK +
Sbjct: 426 TGEKPHGCIQCGKAFSQ-KSHLISHQMTHTG------------EKPFICSKCGKAFSRKS 472
Query: 253 SLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLE 311
L H+++HT Y C+ C K FS ++L NH R+H +PY C C + F L+
Sbjct: 473 QLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLIS 532
Query: 312 HQQSHEGERQEPRWE------EKGMPTTN--GHTDESSQDQLPSAQMLNGSAELSTSGEL 363
HQ++H GE+ E EK T+ HT E + + + ++L+T +
Sbjct: 533 HQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRI 592
Query: 364 EDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFNAAALKNHVR 421
+P+ C C + + LI H ++H TG Y C+ C K ++L NH R
Sbjct: 593 HTG----EKPYECSLCRKAFFEKSELIRHLRTH-TGEKPYECNECRKAFREKSSLINHQR 647
Query: 422 AH--HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGS 479
H +P + E G+ + L+ + TH E +PY CSEC +A+ +
Sbjct: 648 IHTGEKPFE-CSECGKAFSRKSHLIPHQRTHTGE---------KPYGCSECRKAFSQKSQ 697
Query: 480 LVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVH 514
LVNH+ H TGE Y+C C + + L NH R H
Sbjct: 698 LVNHQRIH-TGEKPYRCIECGKAFSQKSQLINHQRTH 733
Score = 159 bits (401), Expect = 3e-38
Identities = 152/624 (24%), Positives = 242/624 (38%), Gaps = 117/624 (18%)
Query: 786 DSLTGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHTCSDCGHSFPHATGLLSHRPCHP- 844
+ L E +K + +P+ H + + G C +CG +FP + ++H H
Sbjct: 204 EKLYECSECRKRFSKKPSLIKHQSRHIRDIAFG----CGNCGKTFPQKSQFITHHRTHTG 259
Query: 845 PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHRRQAH 904
Y CS C K F L SH + H T +P+ C CG F R + + + H
Sbjct: 260 EKPYNCSQCGKAFSQKSQLTSHQRTH-----TGEKPYECGECGKAF-SRKSHLISHWRTH 313
Query: 905 SSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSAGYGHICGCCG 964
+ + G E A S L + ++ ++ E C CG
Sbjct: 314 TGE----------KPYGCNECGRAFSEKSNLINHQRIHTGEKPFE----------CRECG 353
Query: 965 QTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDIVNSVSGEGGDAKS 1024
+ + L HH++ + GT P G + D +
Sbjct: 354 KAFSRKSQLVTHHRTHT-GT------KPFGCS------------------------DCRK 382
Query: 1025 QEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGD--FLCP 1082
+ L I GE +P+ C++C K +R SL+NH++ H TG+ C
Sbjct: 383 AFFEKSELIRHQTIHTGE-------KPYECSECRKAFRERSSLINHQRTH-TGEKPHGCI 434
Query: 1083 VCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAAGSSELQ-VGPIPEGGSNKPQHMAE 1141
C + + + +H H G +P + A S + Q V KP +E
Sbjct: 435 QCGKAFSQKSHLISHQMTH---TGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSE 491
Query: 1142 EGPGQAEVEKLQEELKVEPLEEVARVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSER 1201
G +E L ++ E+ V E + K I Q + E+
Sbjct: 492 CGKAFSEKLSLTNHQRIHTGEK-PYVCSECGKAFCQKSHLISH---------QRTHTGEK 541
Query: 1202 PFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPRRFR 1259
P+ C CG+++ SL H+++H TG + C+ C K FS L H+RIH + +
Sbjct: 542 PYECSECGKAFGEKSSLATHQRTH-TGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYE 600
Query: 1260 CSECGKAFRLRKQLASHQRVHMERR--GGGGTRKATRE-------------DRPFRCGQC 1304
CS C KAF + +L H R H + RKA RE ++PF C +C
Sbjct: 601 CSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSEC 660
Query: 1305 GRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRT 1362
G+ + L+ H+R+H TG+ Y C C K +S + L +HQR+H+ +
Sbjct: 661 GKAFSRKSHLIPHQRTH-TGEKPYGCSECRKAFSQKSQLVNHQRIHTGEK---------- 709
Query: 1363 AVRCALCGRSFPGRGSLERHLREH 1386
RC CG++F + L H R H
Sbjct: 710 PYRCIECGKAFSQKSQLINHQRTH 733
Score = 129 bits (324), Expect = 3e-29
Identities = 83/257 (32%), Positives = 108/257 (42%), Gaps = 12/257 (4%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C CGKT+ Q + H+ T + C C K F SH H + + C +C
Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPR 1650
GKAF L SH + H + A K+ Q + G E P E R
Sbjct: 297 GKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTG-----EKPFEC-R 350
Query: 1651 GPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLC 1709
G++ +R Q VT +PF C+ C +++ L+ HQ HT Y CS C
Sbjct: 351 ECGKAF--SRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSEC 408
Query: 1710 PKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRH 1769
K SL NH RTHT K H C CGKAF + L H H E PF C C +
Sbjct: 409 RKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHT-GEKPFICSKCGKA 467
Query: 1770 FRRRISFVQHQQQHQEE 1786
F R+ V+HQ+ H E
Sbjct: 468 FSRKSQLVRHQRTHTGE 484
Score = 129 bits (324), Expect = 3e-29
Identities = 87/295 (29%), Positives = 126/295 (42%), Gaps = 21/295 (7%)
Query: 1497 PCHAGDCQLNGPTLSHMDS-WDNRDNSSQLQPGSHSSCSQCGKTYCQSGSLLNHNTNKTD 1555
P G+C SH+ S W R ++ + G C++CG+ + + +L+NH T
Sbjct: 290 PYECGECGKAFSRKSHLISHW--RTHTGEKPYG----CNECGRAFSEKSNLINHQRIHTG 343
Query: 1556 RH--YCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQ 1613
C C K F +H H + F C DC KAF EL H H +
Sbjct: 344 EKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHT---GE 400
Query: 1614 VPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVER-ARGGQAVTSMAAED 1672
P + E R KA ++ + E P G + + ++ ++
Sbjct: 401 KPYECSECR--KAFRERSSLI----NHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHT 454
Query: 1673 KERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKR 1731
E+PF C++CG+++ L+ HQ+ HT Y CS C K LSL NH R HT K
Sbjct: 455 GEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKP 514
Query: 1732 HCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
+ CS CGKAF + L H R H E P+ C C + F + S HQ+ H E
Sbjct: 515 YVCSECGKAFCQKSHLISHQRTHT-GEKPYECSECGKAFGEKSSLATHQRTHTGE 568
Score = 129 bits (323), Expect = 3e-29
Identities = 85/277 (30%), Positives = 115/277 (41%), Gaps = 24/277 (8%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
CS+C K + + SL+NH T H C+ C K F SH H + F C C
Sbjct: 405 CSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKC 464
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAG--------TGEDQVVLPGQGKA- 1641
GKAF +L H + H ++ +A K TGE V GKA
Sbjct: 465 GKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAF 524
Query: 1642 -------QEAPSETPRGPGESVERARGGQAVTSMAAEDK----ERPFRCTQCGRSYRHAG 1690
+ T P E E + +S+A + E+P+ C C +++
Sbjct: 525 CQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKS 584
Query: 1691 SLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEG 1749
L HQ+ HT Y CSLC K L H RTHT K + C+ C KAFR + L
Sbjct: 585 QLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLIN 644
Query: 1750 HGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
H R+H E PF C C + F R+ + HQ+ H E
Sbjct: 645 HQRIHT-GEKPFECSECGKAFSRKSHLIPHQRTHTGE 680
Score = 124 bits (310), Expect = 1e-27
Identities = 158/692 (22%), Positives = 259/692 (37%), Gaps = 132/692 (19%)
Query: 604 NSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGDFSCGACAKHFHTMAAMKNHL 663
+S+ E T + + + C +SY+ S +I HR + C C K F ++ H
Sbjct: 167 HSKPEDTDTWLKYYDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKH- 225
Query: 664 RRHSRRRSRRHRKRAGGASGGREAKLLAAESWTRELEDNEGLESPQDPSGESPHGAEGNL 723
+SR R A G G K +S + + + +GE P+
Sbjct: 226 ------QSRHIRDIAFGC--GNCGKTFPQKS--------QFITHHRTHTGEKPYNCS--- 266
Query: 724 ESDGDCLQAESEGDKCGLERDETHFQGDK--ESGGTGEGLERKDASLLDNLDIPGEEGGG 781
C +A S+ K L + G+K E G G+ RK + GE+ G
Sbjct: 267 ----QCGKAFSQ--KSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYG 320
Query: 782 THFCDSLTGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHTCSDCGHSFPHATGLLSHRP 841
+ C A + ++ + TG + C +CG +F + L++H
Sbjct: 321 CNECGR----------AFSEKSNLINHQRIHTGEKP---FECRECGKAFSRKSQLVTHHR 367
Query: 842 CHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHR 900
H + CS C K F L H H T +P+ C C F R+ H+
Sbjct: 368 THTGTKPFGCSDCRKAFFEKSELIRHQTIH-----TGEKPYECSECRKAFRERSSLINHQ 422
Query: 901 RQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSAGYGHIC 960
R H+ + G + A S L ++ + ++ IC
Sbjct: 423 R-THTGE----------KPHGCIQCGKAFSQKSHLISHQMTHTGEKPF----------IC 461
Query: 961 GCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDIVNSVSGEGG 1020
CG+ + L RH ++ + + E G
Sbjct: 462 SKCGKAFSRKSQLVRHQRTHTGEKPYE----------------------------CSECG 493
Query: 1021 DAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGD-- 1078
A S++ L + I GE +P+ C++CGK + L++H++ H TG+
Sbjct: 494 KAFSEK---LSLTNHQRIHTGE-------KPYVCSECGKAFCQKSHLISHQRTH-TGEKP 542
Query: 1079 FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAAGSSELQVGPIPE-GGSNKPQ 1137
+ C C + + ++ H R H G +P E A S + Q+ KP
Sbjct: 543 YECSECGKAFGEKSSLATHQRTHT---GEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPY 599
Query: 1138 HMAEEGPGQAEVEKLQEELKVEPLE---EVARVKEEVWEETTVKGEEIEPRLETAEKGCQ 1194
+ E +L L+ E E ++ E++++ + R+ T EK
Sbjct: 600 ECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQ---RIHTGEK--- 653
Query: 1195 TEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIH 1252
PF C CG+++ LI H+++H TG +GC C K FS L NH+RIH
Sbjct: 654 -------PFECSECGKAFSRKSHLIPHQRTH-TGEKPYGCSECRKAFSQKSQLVNHQRIH 705
Query: 1253 ADPRRFRCSECGKAFRLRKQLASHQRVHMERR 1284
+ +RC ECGKAF + QL +HQR H ++
Sbjct: 706 TGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737
Score = 123 bits (308), Expect = 2e-27
Identities = 77/259 (29%), Positives = 114/259 (44%), Gaps = 14/259 (5%)
Query: 1532 SCSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPD 1589
+CSQCGK + Q L +H T + C C K F SH H + + C +
Sbjct: 264 NCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNE 323
Query: 1590 CGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETP 1649
CG+AF L +H + H + P + E KA + + Q+V + P
Sbjct: 324 CGRAFSEKSNLINHQRIHT---GEKPFECREC--GKAFSRKSQLVTHHRTHTGTKPFGCS 378
Query: 1650 RGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGLYP--CS 1707
E++ + + E+P+ C++C +++R SL+NHQ+ H TG P C
Sbjct: 379 DCRKAFFEKS---ELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTH-TGEKPHGCI 434
Query: 1708 LCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCP 1767
C K L +H THT K CS CGKAF ++L H R H E P+ C C
Sbjct: 435 QCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHT-GEKPYECSECG 493
Query: 1768 RHFRRRISFVQHQQQHQEE 1786
+ F ++S HQ+ H E
Sbjct: 494 KAFSEKLSLTNHQRIHTGE 512
Score = 113 bits (283), Expect = 1e-24
Identities = 73/257 (28%), Positives = 108/257 (42%), Gaps = 13/257 (5%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDRHY-CLLCSKEFLNPVATKSHSHNHIDAQTFACPDCG 1591
C + ++Y +S ++ H ++ Y C C K F + H HI F C +CG
Sbjct: 182 CDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCG 241
Query: 1592 KAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRG 1651
K F + +H + H +Q +A K+ Q G E P
Sbjct: 242 KTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTG---------EKPYE 292
Query: 1652 PGESVER-ARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLC 1709
GE + +R ++ E+P+ C +CGR++ +L+NHQ+ HT + C C
Sbjct: 293 CGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECREC 352
Query: 1710 PKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRH 1769
K L H RTHT K CS C KAF + L H +H E P+ C C +
Sbjct: 353 GKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHT-GEKPYECSECRKA 411
Query: 1770 FRRRISFVQHQQQHQEE 1786
FR R S + HQ+ H E
Sbjct: 412 FRERSSLINHQRTHTGE 428
Score = 111 bits (277), Expect = 7e-24
Identities = 66/229 (28%), Positives = 101/229 (44%), Gaps = 11/229 (4%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
CS+CGK +CQ L++H T + C C K F + +H H + + C DC
Sbjct: 517 CSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDC 576
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPR 1650
KAF +L +H + H + P + R KA + +++ + E P E
Sbjct: 577 EKAFSQKSQLNTHQRIHT---GEKPYECSLCR--KAFFEKSELIRHLRTHTGEKPYECNE 631
Query: 1651 GPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLC 1709
E++ + E+PF C++CG+++ L+ HQ+ HT Y CS C
Sbjct: 632 CRKAFREKS---SLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSEC 688
Query: 1710 PKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPRE 1758
K L NH R HT K + C CGKAF ++L H R H ++
Sbjct: 689 RKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737
Score = 58.9 bits (141), Expect = 4e-08
Identities = 38/138 (27%), Positives = 57/138 (41%), Gaps = 29/138 (21%)
Query: 1677 FRCTQCGRSYRHAGSLLNHQKAHTTGLYPCSLCPKLL---PNLLSLKN------------ 1721
+ C + SY+ + ++ H+ LY CS C K P+L+ ++
Sbjct: 180 YDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGN 239
Query: 1722 -------------HSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPR 1768
H RTHT K + CS CGKAF ++L H R H E P+ C C +
Sbjct: 240 CGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHT-GEKPYECGECGK 298
Query: 1769 HFRRRISFVQHQQQHQEE 1786
F R+ + H + H E
Sbjct: 299 AFSRKSHLISHWRTHTGE 316
>gi|239747147 PREDICTED: hypothetical protein XP_002343925 isoform 1
[Homo sapiens]
Length = 738
Score = 196 bits (499), Expect = 1e-49
Identities = 160/612 (26%), Positives = 234/612 (38%), Gaps = 110/612 (17%)
Query: 1200 ERPFSCEVCGRSYKHAGSLINHRQSH-QTGHFGCQACSKGFSNLMSLKNHRRIHADPRRF 1258
E+ + C C + + SLI H+ H + FGC C K F H R H + +
Sbjct: 204 EKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPY 263
Query: 1259 RCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHR 1318
CS+CGKAF + QL SHQR H ++P+ CG+CG+ + L++H
Sbjct: 264 NCSQCGKAFSQKSQLTSHQRTH-------------TGEKPYECGECGKAFSRKSHLISHW 310
Query: 1319 RSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGR 1376
R+H TG+ Y C C + +S + L +HQR+H+ + C CG++F +
Sbjct: 311 RTH-TGEKPYGCNECGRAFSEKSNLINHQRIHTGEK----------PFECRECGKAFSRK 359
Query: 1377 GSLERHLREHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRP 1436
L H R H T+ G ++ L Q + T G +P E R
Sbjct: 360 SQLVTHHRTHTGTK---PFGCSDCRKAFFEKSELIRHQTIHT---GEKP---YECSECRK 410
Query: 1437 GERSQSPI----RAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEP--- 1489
R +S + R + E P G G S Q E+P
Sbjct: 411 AFRERSSLINHQRTHTGEKPH---------GCIQCGKAFSQKSHLISHQMTHTGEKPFIC 461
Query: 1490 ----------EDSVHRSPCHAG----DCQLNGPTLSHMDSWDNRDN-SSQLQPGSHSSCS 1534
V H G +C G S S N + +P S C
Sbjct: 462 SKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSEC- 520
Query: 1535 QCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGK 1592
GK +CQ L++H T + C C K F + +H H + + C DC K
Sbjct: 521 --GKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEK 578
Query: 1593 AFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGP 1652
AF +L +H + H TGE KA SE
Sbjct: 579 AFSQKSQLNTHQRIH--------------------TGEKPYECSLCRKAFFEKSE----- 613
Query: 1653 GESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLCPK 1711
+ + E+P+ C +C +++R SL+NHQ+ HT + CS C K
Sbjct: 614 -----------LIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGK 662
Query: 1712 LLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFR 1771
L H RTHT K + CS C KAF ++L H R+H E P+ C C + F
Sbjct: 663 AFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHT-GEKPYRCIECGKAFS 721
Query: 1772 RRISFVQHQQQH 1783
++ + HQ+ H
Sbjct: 722 QKSQLINHQRTH 733
Score = 169 bits (429), Expect = 2e-41
Identities = 166/670 (24%), Positives = 256/670 (38%), Gaps = 125/670 (18%)
Query: 30 LHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRTHETGLFPCTTCGKDFSNPMA 89
LH P E+ D+ + Y C + Y+ ++ HR L+ C+ C K FS
Sbjct: 166 LHSKP----EDTDTWLKYYDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSK--- 218
Query: 90 LKSHMRTHAPEGRRRHRPPRPKEATPHLQGETVSTDSWGQRLGS-SEGWENQTKHTEETP 148
+P K + H++ + G+ S+ + HT E P
Sbjct: 219 ----------------KPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKP 262
Query: 149 -DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGADGWGPSTNSARAPPLPIPASSLL 207
+C +A S Q+ L SH G P
Sbjct: 263 YNCSQCG--KAFS---------QKSQLTSHQRTHTGEK------------PYECGECGKA 299
Query: 208 SNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSHTLGIYP 267
+ + +L TG E+ Y C++CG+ + +L NH++ HT G P
Sbjct: 300 FSRKSHLISHWRTHTG------------EKPYGCNECGRAFSEKSNLINHQRIHT-GEKP 346
Query: 268 --CAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGE------ 319
C C K FS L H R H +P+ C C + F EL+ HQ H GE
Sbjct: 347 FECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECS 406
Query: 320 --RQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCG 377
R+ R + HT E + + + + L S ++ +G +PF C
Sbjct: 407 ECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHL-ISHQMTHTG---EKPFICS 462
Query: 378 DCGRTYRHAGSLINHRKSHQTGV--YPCSLCSKQLFNAAALKNHVRAHHRPRQGV-GENG 434
CG+ + L+ H+++H TG Y CS C K +L NH R H + V E G
Sbjct: 463 KCGKAFSRKSQLVRHQRTH-TGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECG 521
Query: 435 QPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--Y 492
+ + L+ + TH E +PY+CSECG+A+ + SL H+ +H TGE Y
Sbjct: 522 KAFCQKSHLISHQRTHTGE---------KPYECSECGKAFGEKSSLATHQRTH-TGEKPY 571
Query: 493 QCSLCPRKYPNLMALRNHVRVH-------CKAARRSADIGAEGAPSHLKVELPPDPVEAE 545
+C C + + L H R+H C R++ +E HL+ P E
Sbjct: 572 ECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSE-LIRHLRTHTGEKPYECN 630
Query: 546 AAPHT--DQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKE 603
++ + H+ T P CS CG F L H TH GEK
Sbjct: 631 ECRKAFREKSSLINHQRIHTGEKPFE-------CSECGKAFSRKSHLIPHQRTH-TGEKP 682
Query: 604 NSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKN 661
+ C +C K++ L+NH++ H TG+ + C C K F + + N
Sbjct: 683 -------------YGCSECRKAFSQKSQLVNHQRIH-TGEKPYRCIECGKAFSQKSQLIN 728
Query: 662 HLRRHSRRRS 671
H R H+ ++S
Sbjct: 729 HQRTHTVKKS 738
Score = 164 bits (414), Expect = 1e-39
Identities = 156/577 (27%), Positives = 230/577 (39%), Gaps = 124/577 (21%)
Query: 10 CSDCQRHFPSLPELSRHREL--------------LHPSPNQ--DSEEADSIPRPYRCQQC 53
CS+C++ F P L +H+ P +Q + +PY C QC
Sbjct: 209 CSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQC 268
Query: 54 GRGYRHPGSLVNHRRTHETGLFP--CTTCGKDFSNPMALKSHMRTHAPE--------GR- 102
G+ + L +H+RTH TG P C CGK FS L SH RTH E GR
Sbjct: 269 GKAFSQKSQLTSHQRTH-TGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRA 327
Query: 103 -----------RRHRPPRPKEA-------------TPHLQGETVS-----TDSWGQRLGS 133
R H +P E H + T + +D
Sbjct: 328 FSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEK 387
Query: 134 SEGWENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGADGWGPSTN 192
SE +QT HT E P +C + R A R+R L +H T+
Sbjct: 388 SELIRHQTIHTGEKPYECS---ECRKA--------FRERSSLINH-----------QRTH 425
Query: 193 SARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGKTYKHAG 252
+ P I S + +L + TG E+ + CS+CGK +
Sbjct: 426 TGEKPHGCIQCGKAFSQ-KSHLISHQMTHTG------------EKPFICSKCGKAFSRKS 472
Query: 253 SLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLE 311
L H+++HT Y C+ C K FS ++L NH R+H +PY C C + F L+
Sbjct: 473 QLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLIS 532
Query: 312 HQQSHEGERQEPRWE------EKGMPTTN--GHTDESSQDQLPSAQMLNGSAELSTSGEL 363
HQ++H GE+ E EK T+ HT E + + + ++L+T +
Sbjct: 533 HQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRI 592
Query: 364 EDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFNAAALKNHVR 421
+P+ C C + + LI H ++H TG Y C+ C K ++L NH R
Sbjct: 593 HTG----EKPYECSLCRKAFFEKSELIRHLRTH-TGEKPYECNECRKAFREKSSLINHQR 647
Query: 422 AH--HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGS 479
H +P + E G+ + L+ + TH E +PY CSEC +A+ +
Sbjct: 648 IHTGEKPFE-CSECGKAFSRKSHLIPHQRTHTGE---------KPYGCSECRKAFSQKSQ 697
Query: 480 LVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVH 514
LVNH+ H TGE Y+C C + + L NH R H
Sbjct: 698 LVNHQRIH-TGEKPYRCIECGKAFSQKSQLINHQRTH 733
Score = 159 bits (401), Expect = 3e-38
Identities = 152/624 (24%), Positives = 242/624 (38%), Gaps = 117/624 (18%)
Query: 786 DSLTGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHTCSDCGHSFPHATGLLSHRPCHP- 844
+ L E +K + +P+ H + + G C +CG +FP + ++H H
Sbjct: 204 EKLYECSECRKRFSKKPSLIKHQSRHIRDIAFG----CGNCGKTFPQKSQFITHHRTHTG 259
Query: 845 PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHRRQAH 904
Y CS C K F L SH + H T +P+ C CG F R + + + H
Sbjct: 260 EKPYNCSQCGKAFSQKSQLTSHQRTH-----TGEKPYECGECGKAF-SRKSHLISHWRTH 313
Query: 905 SSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSAGYGHICGCCG 964
+ + G E A S L + ++ ++ E C CG
Sbjct: 314 TGE----------KPYGCNECGRAFSEKSNLINHQRIHTGEKPFE----------CRECG 353
Query: 965 QTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDIVNSVSGEGGDAKS 1024
+ + L HH++ + GT P G + D +
Sbjct: 354 KAFSRKSQLVTHHRTHT-GT------KPFGCS------------------------DCRK 382
Query: 1025 QEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGD--FLCP 1082
+ L I GE +P+ C++C K +R SL+NH++ H TG+ C
Sbjct: 383 AFFEKSELIRHQTIHTGE-------KPYECSECRKAFRERSSLINHQRTH-TGEKPHGCI 434
Query: 1083 VCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAAGSSELQ-VGPIPEGGSNKPQHMAE 1141
C + + + +H H G +P + A S + Q V KP +E
Sbjct: 435 QCGKAFSQKSHLISHQMTH---TGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSE 491
Query: 1142 EGPGQAEVEKLQEELKVEPLEEVARVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSER 1201
G +E L ++ E+ V E + K I Q + E+
Sbjct: 492 CGKAFSEKLSLTNHQRIHTGEK-PYVCSECGKAFCQKSHLISH---------QRTHTGEK 541
Query: 1202 PFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPRRFR 1259
P+ C CG+++ SL H+++H TG + C+ C K FS L H+RIH + +
Sbjct: 542 PYECSECGKAFGEKSSLATHQRTH-TGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYE 600
Query: 1260 CSECGKAFRLRKQLASHQRVHMERR--GGGGTRKATRE-------------DRPFRCGQC 1304
CS C KAF + +L H R H + RKA RE ++PF C +C
Sbjct: 601 CSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSEC 660
Query: 1305 GRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRT 1362
G+ + L+ H+R+H TG+ Y C C K +S + L +HQR+H+ +
Sbjct: 661 GKAFSRKSHLIPHQRTH-TGEKPYGCSECRKAFSQKSQLVNHQRIHTGEK---------- 709
Query: 1363 AVRCALCGRSFPGRGSLERHLREH 1386
RC CG++F + L H R H
Sbjct: 710 PYRCIECGKAFSQKSQLINHQRTH 733
Score = 129 bits (324), Expect = 3e-29
Identities = 83/257 (32%), Positives = 108/257 (42%), Gaps = 12/257 (4%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C CGKT+ Q + H+ T + C C K F SH H + + C +C
Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPR 1650
GKAF L SH + H + A K+ Q + G E P E R
Sbjct: 297 GKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTG-----EKPFEC-R 350
Query: 1651 GPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLC 1709
G++ +R Q VT +PF C+ C +++ L+ HQ HT Y CS C
Sbjct: 351 ECGKAF--SRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSEC 408
Query: 1710 PKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRH 1769
K SL NH RTHT K H C CGKAF + L H H E PF C C +
Sbjct: 409 RKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHT-GEKPFICSKCGKA 467
Query: 1770 FRRRISFVQHQQQHQEE 1786
F R+ V+HQ+ H E
Sbjct: 468 FSRKSQLVRHQRTHTGE 484
Score = 129 bits (324), Expect = 3e-29
Identities = 87/295 (29%), Positives = 126/295 (42%), Gaps = 21/295 (7%)
Query: 1497 PCHAGDCQLNGPTLSHMDS-WDNRDNSSQLQPGSHSSCSQCGKTYCQSGSLLNHNTNKTD 1555
P G+C SH+ S W R ++ + G C++CG+ + + +L+NH T
Sbjct: 290 PYECGECGKAFSRKSHLISHW--RTHTGEKPYG----CNECGRAFSEKSNLINHQRIHTG 343
Query: 1556 RH--YCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQ 1613
C C K F +H H + F C DC KAF EL H H +
Sbjct: 344 EKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHT---GE 400
Query: 1614 VPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVER-ARGGQAVTSMAAED 1672
P + E R KA ++ + E P G + + ++ ++
Sbjct: 401 KPYECSECR--KAFRERSSLI----NHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHT 454
Query: 1673 KERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKR 1731
E+PF C++CG+++ L+ HQ+ HT Y CS C K LSL NH R HT K
Sbjct: 455 GEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKP 514
Query: 1732 HCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
+ CS CGKAF + L H R H E P+ C C + F + S HQ+ H E
Sbjct: 515 YVCSECGKAFCQKSHLISHQRTHT-GEKPYECSECGKAFGEKSSLATHQRTHTGE 568
Score = 129 bits (323), Expect = 3e-29
Identities = 85/277 (30%), Positives = 115/277 (41%), Gaps = 24/277 (8%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
CS+C K + + SL+NH T H C+ C K F SH H + F C C
Sbjct: 405 CSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKC 464
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAG--------TGEDQVVLPGQGKA- 1641
GKAF +L H + H ++ +A K TGE V GKA
Sbjct: 465 GKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAF 524
Query: 1642 -------QEAPSETPRGPGESVERARGGQAVTSMAAEDK----ERPFRCTQCGRSYRHAG 1690
+ T P E E + +S+A + E+P+ C C +++
Sbjct: 525 CQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKS 584
Query: 1691 SLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEG 1749
L HQ+ HT Y CSLC K L H RTHT K + C+ C KAFR + L
Sbjct: 585 QLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLIN 644
Query: 1750 HGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
H R+H E PF C C + F R+ + HQ+ H E
Sbjct: 645 HQRIHT-GEKPFECSECGKAFSRKSHLIPHQRTHTGE 680
Score = 124 bits (310), Expect = 1e-27
Identities = 158/692 (22%), Positives = 259/692 (37%), Gaps = 132/692 (19%)
Query: 604 NSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGDFSCGACAKHFHTMAAMKNHL 663
+S+ E T + + + C +SY+ S +I HR + C C K F ++ H
Sbjct: 167 HSKPEDTDTWLKYYDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKH- 225
Query: 664 RRHSRRRSRRHRKRAGGASGGREAKLLAAESWTRELEDNEGLESPQDPSGESPHGAEGNL 723
+SR R A G G K +S + + + +GE P+
Sbjct: 226 ------QSRHIRDIAFGC--GNCGKTFPQKS--------QFITHHRTHTGEKPYNCS--- 266
Query: 724 ESDGDCLQAESEGDKCGLERDETHFQGDK--ESGGTGEGLERKDASLLDNLDIPGEEGGG 781
C +A S+ K L + G+K E G G+ RK + GE+ G
Sbjct: 267 ----QCGKAFSQ--KSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYG 320
Query: 782 THFCDSLTGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHTCSDCGHSFPHATGLLSHRP 841
+ C A + ++ + TG + C +CG +F + L++H
Sbjct: 321 CNECGR----------AFSEKSNLINHQRIHTGEKP---FECRECGKAFSRKSQLVTHHR 367
Query: 842 CHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHR 900
H + CS C K F L H H T +P+ C C F R+ H+
Sbjct: 368 THTGTKPFGCSDCRKAFFEKSELIRHQTIH-----TGEKPYECSECRKAFRERSSLINHQ 422
Query: 901 RQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSAGYGHIC 960
R H+ + G + A S L ++ + ++ IC
Sbjct: 423 R-THTGE----------KPHGCIQCGKAFSQKSHLISHQMTHTGEKPF----------IC 461
Query: 961 GCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDIVNSVSGEGG 1020
CG+ + L RH ++ + + E G
Sbjct: 462 SKCGKAFSRKSQLVRHQRTHTGEKPYE----------------------------CSECG 493
Query: 1021 DAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGD-- 1078
A S++ L + I GE +P+ C++CGK + L++H++ H TG+
Sbjct: 494 KAFSEK---LSLTNHQRIHTGE-------KPYVCSECGKAFCQKSHLISHQRTH-TGEKP 542
Query: 1079 FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAAGSSELQVGPIPE-GGSNKPQ 1137
+ C C + + ++ H R H G +P E A S + Q+ KP
Sbjct: 543 YECSECGKAFGEKSSLATHQRTHT---GEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPY 599
Query: 1138 HMAEEGPGQAEVEKLQEELKVEPLE---EVARVKEEVWEETTVKGEEIEPRLETAEKGCQ 1194
+ E +L L+ E E ++ E++++ + R+ T EK
Sbjct: 600 ECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQ---RIHTGEK--- 653
Query: 1195 TEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIH 1252
PF C CG+++ LI H+++H TG +GC C K FS L NH+RIH
Sbjct: 654 -------PFECSECGKAFSRKSHLIPHQRTH-TGEKPYGCSECRKAFSQKSQLVNHQRIH 705
Query: 1253 ADPRRFRCSECGKAFRLRKQLASHQRVHMERR 1284
+ +RC ECGKAF + QL +HQR H ++
Sbjct: 706 TGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737
Score = 123 bits (308), Expect = 2e-27
Identities = 77/259 (29%), Positives = 114/259 (44%), Gaps = 14/259 (5%)
Query: 1532 SCSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPD 1589
+CSQCGK + Q L +H T + C C K F SH H + + C +
Sbjct: 264 NCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNE 323
Query: 1590 CGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETP 1649
CG+AF L +H + H + P + E KA + + Q+V + P
Sbjct: 324 CGRAFSEKSNLINHQRIHT---GEKPFECREC--GKAFSRKSQLVTHHRTHTGTKPFGCS 378
Query: 1650 RGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGLYP--CS 1707
E++ + + E+P+ C++C +++R SL+NHQ+ H TG P C
Sbjct: 379 DCRKAFFEKS---ELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTH-TGEKPHGCI 434
Query: 1708 LCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCP 1767
C K L +H THT K CS CGKAF ++L H R H E P+ C C
Sbjct: 435 QCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHT-GEKPYECSECG 493
Query: 1768 RHFRRRISFVQHQQQHQEE 1786
+ F ++S HQ+ H E
Sbjct: 494 KAFSEKLSLTNHQRIHTGE 512
Score = 113 bits (283), Expect = 1e-24
Identities = 73/257 (28%), Positives = 108/257 (42%), Gaps = 13/257 (5%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDRHY-CLLCSKEFLNPVATKSHSHNHIDAQTFACPDCG 1591
C + ++Y +S ++ H ++ Y C C K F + H HI F C +CG
Sbjct: 182 CDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCG 241
Query: 1592 KAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRG 1651
K F + +H + H +Q +A K+ Q G E P
Sbjct: 242 KTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTG---------EKPYE 292
Query: 1652 PGESVER-ARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLC 1709
GE + +R ++ E+P+ C +CGR++ +L+NHQ+ HT + C C
Sbjct: 293 CGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECREC 352
Query: 1710 PKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRH 1769
K L H RTHT K CS C KAF + L H +H E P+ C C +
Sbjct: 353 GKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHT-GEKPYECSECRKA 411
Query: 1770 FRRRISFVQHQQQHQEE 1786
FR R S + HQ+ H E
Sbjct: 412 FRERSSLINHQRTHTGE 428
Score = 111 bits (277), Expect = 7e-24
Identities = 66/229 (28%), Positives = 101/229 (44%), Gaps = 11/229 (4%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
CS+CGK +CQ L++H T + C C K F + +H H + + C DC
Sbjct: 517 CSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDC 576
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPR 1650
KAF +L +H + H + P + R KA + +++ + E P E
Sbjct: 577 EKAFSQKSQLNTHQRIHT---GEKPYECSLCR--KAFFEKSELIRHLRTHTGEKPYECNE 631
Query: 1651 GPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLC 1709
E++ + E+PF C++CG+++ L+ HQ+ HT Y CS C
Sbjct: 632 CRKAFREKS---SLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSEC 688
Query: 1710 PKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPRE 1758
K L NH R HT K + C CGKAF ++L H R H ++
Sbjct: 689 RKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737
Score = 58.9 bits (141), Expect = 4e-08
Identities = 38/138 (27%), Positives = 57/138 (41%), Gaps = 29/138 (21%)
Query: 1677 FRCTQCGRSYRHAGSLLNHQKAHTTGLYPCSLCPKLL---PNLLSLKN------------ 1721
+ C + SY+ + ++ H+ LY CS C K P+L+ ++
Sbjct: 180 YDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGN 239
Query: 1722 -------------HSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPR 1768
H RTHT K + CS CGKAF ++L H R H E P+ C C +
Sbjct: 240 CGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHT-GEKPYECGECGK 298
Query: 1769 HFRRRISFVQHQQQHQEE 1786
F R+ + H + H E
Sbjct: 299 AFSRKSHLISHWRTHTGE 316
>gi|239747145 PREDICTED: hypothetical protein XP_002343927 isoform 3
[Homo sapiens]
Length = 738
Score = 196 bits (499), Expect = 1e-49
Identities = 160/612 (26%), Positives = 234/612 (38%), Gaps = 110/612 (17%)
Query: 1200 ERPFSCEVCGRSYKHAGSLINHRQSH-QTGHFGCQACSKGFSNLMSLKNHRRIHADPRRF 1258
E+ + C C + + SLI H+ H + FGC C K F H R H + +
Sbjct: 204 EKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPY 263
Query: 1259 RCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHR 1318
CS+CGKAF + QL SHQR H ++P+ CG+CG+ + L++H
Sbjct: 264 NCSQCGKAFSQKSQLTSHQRTH-------------TGEKPYECGECGKAFSRKSHLISHW 310
Query: 1319 RSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGR 1376
R+H TG+ Y C C + +S + L +HQR+H+ + C CG++F +
Sbjct: 311 RTH-TGEKPYGCNECGRAFSEKSNLINHQRIHTGEK----------PFECRECGKAFSRK 359
Query: 1377 GSLERHLREHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRP 1436
L H R H T+ G ++ L Q + T G +P E R
Sbjct: 360 SQLVTHHRTHTGTK---PFGCSDCRKAFFEKSELIRHQTIHT---GEKP---YECSECRK 410
Query: 1437 GERSQSPI----RAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEP--- 1489
R +S + R + E P G G S Q E+P
Sbjct: 411 AFRERSSLINHQRTHTGEKPH---------GCIQCGKAFSQKSHLISHQMTHTGEKPFIC 461
Query: 1490 ----------EDSVHRSPCHAG----DCQLNGPTLSHMDSWDNRDN-SSQLQPGSHSSCS 1534
V H G +C G S S N + +P S C
Sbjct: 462 SKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSEC- 520
Query: 1535 QCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGK 1592
GK +CQ L++H T + C C K F + +H H + + C DC K
Sbjct: 521 --GKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEK 578
Query: 1593 AFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGP 1652
AF +L +H + H TGE KA SE
Sbjct: 579 AFSQKSQLNTHQRIH--------------------TGEKPYECSLCRKAFFEKSE----- 613
Query: 1653 GESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLCPK 1711
+ + E+P+ C +C +++R SL+NHQ+ HT + CS C K
Sbjct: 614 -----------LIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGK 662
Query: 1712 LLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFR 1771
L H RTHT K + CS C KAF ++L H R+H E P+ C C + F
Sbjct: 663 AFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHT-GEKPYRCIECGKAFS 721
Query: 1772 RRISFVQHQQQH 1783
++ + HQ+ H
Sbjct: 722 QKSQLINHQRTH 733
Score = 169 bits (429), Expect = 2e-41
Identities = 166/670 (24%), Positives = 256/670 (38%), Gaps = 125/670 (18%)
Query: 30 LHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRTHETGLFPCTTCGKDFSNPMA 89
LH P E+ D+ + Y C + Y+ ++ HR L+ C+ C K FS
Sbjct: 166 LHSKP----EDTDTWLKYYDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSK--- 218
Query: 90 LKSHMRTHAPEGRRRHRPPRPKEATPHLQGETVSTDSWGQRLGS-SEGWENQTKHTEETP 148
+P K + H++ + G+ S+ + HT E P
Sbjct: 219 ----------------KPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKP 262
Query: 149 -DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGADGWGPSTNSARAPPLPIPASSLL 207
+C +A S Q+ L SH G P
Sbjct: 263 YNCSQCG--KAFS---------QKSQLTSHQRTHTGEK------------PYECGECGKA 299
Query: 208 SNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSHTLGIYP 267
+ + +L TG E+ Y C++CG+ + +L NH++ HT G P
Sbjct: 300 FSRKSHLISHWRTHTG------------EKPYGCNECGRAFSEKSNLINHQRIHT-GEKP 346
Query: 268 --CAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGE------ 319
C C K FS L H R H +P+ C C + F EL+ HQ H GE
Sbjct: 347 FECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECS 406
Query: 320 --RQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCG 377
R+ R + HT E + + + + L S ++ +G +PF C
Sbjct: 407 ECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHL-ISHQMTHTG---EKPFICS 462
Query: 378 DCGRTYRHAGSLINHRKSHQTGV--YPCSLCSKQLFNAAALKNHVRAHHRPRQGV-GENG 434
CG+ + L+ H+++H TG Y CS C K +L NH R H + V E G
Sbjct: 463 KCGKAFSRKSQLVRHQRTH-TGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECG 521
Query: 435 QPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--Y 492
+ + L+ + TH E +PY+CSECG+A+ + SL H+ +H TGE Y
Sbjct: 522 KAFCQKSHLISHQRTHTGE---------KPYECSECGKAFGEKSSLATHQRTH-TGEKPY 571
Query: 493 QCSLCPRKYPNLMALRNHVRVH-------CKAARRSADIGAEGAPSHLKVELPPDPVEAE 545
+C C + + L H R+H C R++ +E HL+ P E
Sbjct: 572 ECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSE-LIRHLRTHTGEKPYECN 630
Query: 546 AAPHT--DQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKE 603
++ + H+ T P CS CG F L H TH GEK
Sbjct: 631 ECRKAFREKSSLINHQRIHTGEKPFE-------CSECGKAFSRKSHLIPHQRTH-TGEKP 682
Query: 604 NSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKN 661
+ C +C K++ L+NH++ H TG+ + C C K F + + N
Sbjct: 683 -------------YGCSECRKAFSQKSQLVNHQRIH-TGEKPYRCIECGKAFSQKSQLIN 728
Query: 662 HLRRHSRRRS 671
H R H+ ++S
Sbjct: 729 HQRTHTVKKS 738
Score = 164 bits (414), Expect = 1e-39
Identities = 156/577 (27%), Positives = 230/577 (39%), Gaps = 124/577 (21%)
Query: 10 CSDCQRHFPSLPELSRHREL--------------LHPSPNQ--DSEEADSIPRPYRCQQC 53
CS+C++ F P L +H+ P +Q + +PY C QC
Sbjct: 209 CSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQC 268
Query: 54 GRGYRHPGSLVNHRRTHETGLFP--CTTCGKDFSNPMALKSHMRTHAPE--------GR- 102
G+ + L +H+RTH TG P C CGK FS L SH RTH E GR
Sbjct: 269 GKAFSQKSQLTSHQRTH-TGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRA 327
Query: 103 -----------RRHRPPRPKEA-------------TPHLQGETVS-----TDSWGQRLGS 133
R H +P E H + T + +D
Sbjct: 328 FSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEK 387
Query: 134 SEGWENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGADGWGPSTN 192
SE +QT HT E P +C + R A R+R L +H T+
Sbjct: 388 SELIRHQTIHTGEKPYECS---ECRKA--------FRERSSLINH-----------QRTH 425
Query: 193 SARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGKTYKHAG 252
+ P I S + +L + TG E+ + CS+CGK +
Sbjct: 426 TGEKPHGCIQCGKAFSQ-KSHLISHQMTHTG------------EKPFICSKCGKAFSRKS 472
Query: 253 SLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLE 311
L H+++HT Y C+ C K FS ++L NH R+H +PY C C + F L+
Sbjct: 473 QLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLIS 532
Query: 312 HQQSHEGERQEPRWE------EKGMPTTN--GHTDESSQDQLPSAQMLNGSAELSTSGEL 363
HQ++H GE+ E EK T+ HT E + + + ++L+T +
Sbjct: 533 HQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRI 592
Query: 364 EDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFNAAALKNHVR 421
+P+ C C + + LI H ++H TG Y C+ C K ++L NH R
Sbjct: 593 HTG----EKPYECSLCRKAFFEKSELIRHLRTH-TGEKPYECNECRKAFREKSSLINHQR 647
Query: 422 AH--HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGS 479
H +P + E G+ + L+ + TH E +PY CSEC +A+ +
Sbjct: 648 IHTGEKPFE-CSECGKAFSRKSHLIPHQRTHTGE---------KPYGCSECRKAFSQKSQ 697
Query: 480 LVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVH 514
LVNH+ H TGE Y+C C + + L NH R H
Sbjct: 698 LVNHQRIH-TGEKPYRCIECGKAFSQKSQLINHQRTH 733
Score = 159 bits (401), Expect = 3e-38
Identities = 152/624 (24%), Positives = 242/624 (38%), Gaps = 117/624 (18%)
Query: 786 DSLTGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHTCSDCGHSFPHATGLLSHRPCHP- 844
+ L E +K + +P+ H + + G C +CG +FP + ++H H
Sbjct: 204 EKLYECSECRKRFSKKPSLIKHQSRHIRDIAFG----CGNCGKTFPQKSQFITHHRTHTG 259
Query: 845 PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHRRQAH 904
Y CS C K F L SH + H T +P+ C CG F R + + + H
Sbjct: 260 EKPYNCSQCGKAFSQKSQLTSHQRTH-----TGEKPYECGECGKAF-SRKSHLISHWRTH 313
Query: 905 SSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSAGYGHICGCCG 964
+ + G E A S L + ++ ++ E C CG
Sbjct: 314 TGE----------KPYGCNECGRAFSEKSNLINHQRIHTGEKPFE----------CRECG 353
Query: 965 QTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDIVNSVSGEGGDAKS 1024
+ + L HH++ + GT P G + D +
Sbjct: 354 KAFSRKSQLVTHHRTHT-GT------KPFGCS------------------------DCRK 382
Query: 1025 QEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGD--FLCP 1082
+ L I GE +P+ C++C K +R SL+NH++ H TG+ C
Sbjct: 383 AFFEKSELIRHQTIHTGE-------KPYECSECRKAFRERSSLINHQRTH-TGEKPHGCI 434
Query: 1083 VCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAAGSSELQ-VGPIPEGGSNKPQHMAE 1141
C + + + +H H G +P + A S + Q V KP +E
Sbjct: 435 QCGKAFSQKSHLISHQMTH---TGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSE 491
Query: 1142 EGPGQAEVEKLQEELKVEPLEEVARVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSER 1201
G +E L ++ E+ V E + K I Q + E+
Sbjct: 492 CGKAFSEKLSLTNHQRIHTGEK-PYVCSECGKAFCQKSHLISH---------QRTHTGEK 541
Query: 1202 PFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPRRFR 1259
P+ C CG+++ SL H+++H TG + C+ C K FS L H+RIH + +
Sbjct: 542 PYECSECGKAFGEKSSLATHQRTH-TGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYE 600
Query: 1260 CSECGKAFRLRKQLASHQRVHMERR--GGGGTRKATRE-------------DRPFRCGQC 1304
CS C KAF + +L H R H + RKA RE ++PF C +C
Sbjct: 601 CSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSEC 660
Query: 1305 GRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRT 1362
G+ + L+ H+R+H TG+ Y C C K +S + L +HQR+H+ +
Sbjct: 661 GKAFSRKSHLIPHQRTH-TGEKPYGCSECRKAFSQKSQLVNHQRIHTGEK---------- 709
Query: 1363 AVRCALCGRSFPGRGSLERHLREH 1386
RC CG++F + L H R H
Sbjct: 710 PYRCIECGKAFSQKSQLINHQRTH 733
Score = 129 bits (324), Expect = 3e-29
Identities = 83/257 (32%), Positives = 108/257 (42%), Gaps = 12/257 (4%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C CGKT+ Q + H+ T + C C K F SH H + + C +C
Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPR 1650
GKAF L SH + H + A K+ Q + G E P E R
Sbjct: 297 GKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTG-----EKPFEC-R 350
Query: 1651 GPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLC 1709
G++ +R Q VT +PF C+ C +++ L+ HQ HT Y CS C
Sbjct: 351 ECGKAF--SRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSEC 408
Query: 1710 PKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRH 1769
K SL NH RTHT K H C CGKAF + L H H E PF C C +
Sbjct: 409 RKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHT-GEKPFICSKCGKA 467
Query: 1770 FRRRISFVQHQQQHQEE 1786
F R+ V+HQ+ H E
Sbjct: 468 FSRKSQLVRHQRTHTGE 484
Score = 129 bits (324), Expect = 3e-29
Identities = 87/295 (29%), Positives = 126/295 (42%), Gaps = 21/295 (7%)
Query: 1497 PCHAGDCQLNGPTLSHMDS-WDNRDNSSQLQPGSHSSCSQCGKTYCQSGSLLNHNTNKTD 1555
P G+C SH+ S W R ++ + G C++CG+ + + +L+NH T
Sbjct: 290 PYECGECGKAFSRKSHLISHW--RTHTGEKPYG----CNECGRAFSEKSNLINHQRIHTG 343
Query: 1556 RH--YCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQ 1613
C C K F +H H + F C DC KAF EL H H +
Sbjct: 344 EKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHT---GE 400
Query: 1614 VPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVER-ARGGQAVTSMAAED 1672
P + E R KA ++ + E P G + + ++ ++
Sbjct: 401 KPYECSECR--KAFRERSSLI----NHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHT 454
Query: 1673 KERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKR 1731
E+PF C++CG+++ L+ HQ+ HT Y CS C K LSL NH R HT K
Sbjct: 455 GEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKP 514
Query: 1732 HCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
+ CS CGKAF + L H R H E P+ C C + F + S HQ+ H E
Sbjct: 515 YVCSECGKAFCQKSHLISHQRTHT-GEKPYECSECGKAFGEKSSLATHQRTHTGE 568
Score = 129 bits (323), Expect = 3e-29
Identities = 85/277 (30%), Positives = 115/277 (41%), Gaps = 24/277 (8%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
CS+C K + + SL+NH T H C+ C K F SH H + F C C
Sbjct: 405 CSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKC 464
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAG--------TGEDQVVLPGQGKA- 1641
GKAF +L H + H ++ +A K TGE V GKA
Sbjct: 465 GKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAF 524
Query: 1642 -------QEAPSETPRGPGESVERARGGQAVTSMAAEDK----ERPFRCTQCGRSYRHAG 1690
+ T P E E + +S+A + E+P+ C C +++
Sbjct: 525 CQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKS 584
Query: 1691 SLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEG 1749
L HQ+ HT Y CSLC K L H RTHT K + C+ C KAFR + L
Sbjct: 585 QLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLIN 644
Query: 1750 HGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
H R+H E PF C C + F R+ + HQ+ H E
Sbjct: 645 HQRIHT-GEKPFECSECGKAFSRKSHLIPHQRTHTGE 680
Score = 124 bits (310), Expect = 1e-27
Identities = 158/692 (22%), Positives = 259/692 (37%), Gaps = 132/692 (19%)
Query: 604 NSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGDFSCGACAKHFHTMAAMKNHL 663
+S+ E T + + + C +SY+ S +I HR + C C K F ++ H
Sbjct: 167 HSKPEDTDTWLKYYDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKH- 225
Query: 664 RRHSRRRSRRHRKRAGGASGGREAKLLAAESWTRELEDNEGLESPQDPSGESPHGAEGNL 723
+SR R A G G K +S + + + +GE P+
Sbjct: 226 ------QSRHIRDIAFGC--GNCGKTFPQKS--------QFITHHRTHTGEKPYNCS--- 266
Query: 724 ESDGDCLQAESEGDKCGLERDETHFQGDK--ESGGTGEGLERKDASLLDNLDIPGEEGGG 781
C +A S+ K L + G+K E G G+ RK + GE+ G
Sbjct: 267 ----QCGKAFSQ--KSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYG 320
Query: 782 THFCDSLTGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHTCSDCGHSFPHATGLLSHRP 841
+ C A + ++ + TG + C +CG +F + L++H
Sbjct: 321 CNECGR----------AFSEKSNLINHQRIHTGEKP---FECRECGKAFSRKSQLVTHHR 367
Query: 842 CHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHR 900
H + CS C K F L H H T +P+ C C F R+ H+
Sbjct: 368 THTGTKPFGCSDCRKAFFEKSELIRHQTIH-----TGEKPYECSECRKAFRERSSLINHQ 422
Query: 901 RQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSAGYGHIC 960
R H+ + G + A S L ++ + ++ IC
Sbjct: 423 R-THTGE----------KPHGCIQCGKAFSQKSHLISHQMTHTGEKPF----------IC 461
Query: 961 GCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDIVNSVSGEGG 1020
CG+ + L RH ++ + + E G
Sbjct: 462 SKCGKAFSRKSQLVRHQRTHTGEKPYE----------------------------CSECG 493
Query: 1021 DAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGD-- 1078
A S++ L + I GE +P+ C++CGK + L++H++ H TG+
Sbjct: 494 KAFSEK---LSLTNHQRIHTGE-------KPYVCSECGKAFCQKSHLISHQRTH-TGEKP 542
Query: 1079 FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAAGSSELQVGPIPE-GGSNKPQ 1137
+ C C + + ++ H R H G +P E A S + Q+ KP
Sbjct: 543 YECSECGKAFGEKSSLATHQRTHT---GEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPY 599
Query: 1138 HMAEEGPGQAEVEKLQEELKVEPLE---EVARVKEEVWEETTVKGEEIEPRLETAEKGCQ 1194
+ E +L L+ E E ++ E++++ + R+ T EK
Sbjct: 600 ECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQ---RIHTGEK--- 653
Query: 1195 TEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIH 1252
PF C CG+++ LI H+++H TG +GC C K FS L NH+RIH
Sbjct: 654 -------PFECSECGKAFSRKSHLIPHQRTH-TGEKPYGCSECRKAFSQKSQLVNHQRIH 705
Query: 1253 ADPRRFRCSECGKAFRLRKQLASHQRVHMERR 1284
+ +RC ECGKAF + QL +HQR H ++
Sbjct: 706 TGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737
Score = 123 bits (308), Expect = 2e-27
Identities = 77/259 (29%), Positives = 114/259 (44%), Gaps = 14/259 (5%)
Query: 1532 SCSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPD 1589
+CSQCGK + Q L +H T + C C K F SH H + + C +
Sbjct: 264 NCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNE 323
Query: 1590 CGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETP 1649
CG+AF L +H + H + P + E KA + + Q+V + P
Sbjct: 324 CGRAFSEKSNLINHQRIHT---GEKPFECREC--GKAFSRKSQLVTHHRTHTGTKPFGCS 378
Query: 1650 RGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGLYP--CS 1707
E++ + + E+P+ C++C +++R SL+NHQ+ H TG P C
Sbjct: 379 DCRKAFFEKS---ELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTH-TGEKPHGCI 434
Query: 1708 LCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCP 1767
C K L +H THT K CS CGKAF ++L H R H E P+ C C
Sbjct: 435 QCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHT-GEKPYECSECG 493
Query: 1768 RHFRRRISFVQHQQQHQEE 1786
+ F ++S HQ+ H E
Sbjct: 494 KAFSEKLSLTNHQRIHTGE 512
Score = 113 bits (283), Expect = 1e-24
Identities = 73/257 (28%), Positives = 108/257 (42%), Gaps = 13/257 (5%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDRHY-CLLCSKEFLNPVATKSHSHNHIDAQTFACPDCG 1591
C + ++Y +S ++ H ++ Y C C K F + H HI F C +CG
Sbjct: 182 CDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCG 241
Query: 1592 KAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRG 1651
K F + +H + H +Q +A K+ Q G E P
Sbjct: 242 KTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTG---------EKPYE 292
Query: 1652 PGESVER-ARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLC 1709
GE + +R ++ E+P+ C +CGR++ +L+NHQ+ HT + C C
Sbjct: 293 CGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECREC 352
Query: 1710 PKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRH 1769
K L H RTHT K CS C KAF + L H +H E P+ C C +
Sbjct: 353 GKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHT-GEKPYECSECRKA 411
Query: 1770 FRRRISFVQHQQQHQEE 1786
FR R S + HQ+ H E
Sbjct: 412 FRERSSLINHQRTHTGE 428
Score = 111 bits (277), Expect = 7e-24
Identities = 66/229 (28%), Positives = 101/229 (44%), Gaps = 11/229 (4%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
CS+CGK +CQ L++H T + C C K F + +H H + + C DC
Sbjct: 517 CSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDC 576
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPR 1650
KAF +L +H + H + P + R KA + +++ + E P E
Sbjct: 577 EKAFSQKSQLNTHQRIHT---GEKPYECSLCR--KAFFEKSELIRHLRTHTGEKPYECNE 631
Query: 1651 GPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLC 1709
E++ + E+PF C++CG+++ L+ HQ+ HT Y CS C
Sbjct: 632 CRKAFREKS---SLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSEC 688
Query: 1710 PKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPRE 1758
K L NH R HT K + C CGKAF ++L H R H ++
Sbjct: 689 RKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737
Score = 58.9 bits (141), Expect = 4e-08
Identities = 38/138 (27%), Positives = 57/138 (41%), Gaps = 29/138 (21%)
Query: 1677 FRCTQCGRSYRHAGSLLNHQKAHTTGLYPCSLCPKLL---PNLLSLKN------------ 1721
+ C + SY+ + ++ H+ LY CS C K P+L+ ++
Sbjct: 180 YDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGN 239
Query: 1722 -------------HSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPR 1768
H RTHT K + CS CGKAF ++L H R H E P+ C C +
Sbjct: 240 CGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHT-GEKPYECGECGK 298
Query: 1769 HFRRRISFVQHQQQHQEE 1786
F R+ + H + H E
Sbjct: 299 AFSRKSHLISHWRTHTGE 316
>gi|188497655 zinc finger protein 84 [Homo sapiens]
Length = 738
Score = 196 bits (499), Expect = 1e-49
Identities = 160/612 (26%), Positives = 234/612 (38%), Gaps = 110/612 (17%)
Query: 1200 ERPFSCEVCGRSYKHAGSLINHRQSH-QTGHFGCQACSKGFSNLMSLKNHRRIHADPRRF 1258
E+ + C C + + SLI H+ H + FGC C K F H R H + +
Sbjct: 204 EKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPY 263
Query: 1259 RCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHR 1318
CS+CGKAF + QL SHQR H ++P+ CG+CG+ + L++H
Sbjct: 264 NCSQCGKAFSQKSQLTSHQRTH-------------TGEKPYECGECGKAFSRKSHLISHW 310
Query: 1319 RSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGR 1376
R+H TG+ Y C C + +S + L +HQR+H+ + C CG++F +
Sbjct: 311 RTH-TGEKPYGCNECGRAFSEKSNLINHQRIHTGEK----------PFECRECGKAFSRK 359
Query: 1377 GSLERHLREHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRP 1436
L H R H T+ G ++ L Q + T G +P E R
Sbjct: 360 SQLVTHHRTHTGTK---PFGCSDCRKAFFEKSELIRHQTIHT---GEKP---YECSECRK 410
Query: 1437 GERSQSPI----RAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEP--- 1489
R +S + R + E P G G S Q E+P
Sbjct: 411 AFRERSSLINHQRTHTGEKPH---------GCIQCGKAFSQKSHLISHQMTHTGEKPFIC 461
Query: 1490 ----------EDSVHRSPCHAG----DCQLNGPTLSHMDSWDNRDN-SSQLQPGSHSSCS 1534
V H G +C G S S N + +P S C
Sbjct: 462 SKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSEC- 520
Query: 1535 QCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGK 1592
GK +CQ L++H T + C C K F + +H H + + C DC K
Sbjct: 521 --GKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEK 578
Query: 1593 AFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGP 1652
AF +L +H + H TGE KA SE
Sbjct: 579 AFSQKSQLNTHQRIH--------------------TGEKPYECSLCRKAFFEKSE----- 613
Query: 1653 GESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLCPK 1711
+ + E+P+ C +C +++R SL+NHQ+ HT + CS C K
Sbjct: 614 -----------LIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGK 662
Query: 1712 LLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFR 1771
L H RTHT K + CS C KAF ++L H R+H E P+ C C + F
Sbjct: 663 AFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHT-GEKPYRCIECGKAFS 721
Query: 1772 RRISFVQHQQQH 1783
++ + HQ+ H
Sbjct: 722 QKSQLINHQRTH 733
Score = 169 bits (429), Expect = 2e-41
Identities = 166/670 (24%), Positives = 256/670 (38%), Gaps = 125/670 (18%)
Query: 30 LHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRTHETGLFPCTTCGKDFSNPMA 89
LH P E+ D+ + Y C + Y+ ++ HR L+ C+ C K FS
Sbjct: 166 LHSKP----EDTDTWLKYYDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSK--- 218
Query: 90 LKSHMRTHAPEGRRRHRPPRPKEATPHLQGETVSTDSWGQRLGS-SEGWENQTKHTEETP 148
+P K + H++ + G+ S+ + HT E P
Sbjct: 219 ----------------KPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKP 262
Query: 149 -DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGADGWGPSTNSARAPPLPIPASSLL 207
+C +A S Q+ L SH G P
Sbjct: 263 YNCSQCG--KAFS---------QKSQLTSHQRTHTGEK------------PYECGECGKA 299
Query: 208 SNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSHTLGIYP 267
+ + +L TG E+ Y C++CG+ + +L NH++ HT G P
Sbjct: 300 FSRKSHLISHWRTHTG------------EKPYGCNECGRAFSEKSNLINHQRIHT-GEKP 346
Query: 268 --CAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGE------ 319
C C K FS L H R H +P+ C C + F EL+ HQ H GE
Sbjct: 347 FECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECS 406
Query: 320 --RQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCG 377
R+ R + HT E + + + + L S ++ +G +PF C
Sbjct: 407 ECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHL-ISHQMTHTG---EKPFICS 462
Query: 378 DCGRTYRHAGSLINHRKSHQTGV--YPCSLCSKQLFNAAALKNHVRAHHRPRQGV-GENG 434
CG+ + L+ H+++H TG Y CS C K +L NH R H + V E G
Sbjct: 463 KCGKAFSRKSQLVRHQRTH-TGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECG 521
Query: 435 QPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--Y 492
+ + L+ + TH E +PY+CSECG+A+ + SL H+ +H TGE Y
Sbjct: 522 KAFCQKSHLISHQRTHTGE---------KPYECSECGKAFGEKSSLATHQRTH-TGEKPY 571
Query: 493 QCSLCPRKYPNLMALRNHVRVH-------CKAARRSADIGAEGAPSHLKVELPPDPVEAE 545
+C C + + L H R+H C R++ +E HL+ P E
Sbjct: 572 ECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSE-LIRHLRTHTGEKPYECN 630
Query: 546 AAPHT--DQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKE 603
++ + H+ T P CS CG F L H TH GEK
Sbjct: 631 ECRKAFREKSSLINHQRIHTGEKPFE-------CSECGKAFSRKSHLIPHQRTH-TGEKP 682
Query: 604 NSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKN 661
+ C +C K++ L+NH++ H TG+ + C C K F + + N
Sbjct: 683 -------------YGCSECRKAFSQKSQLVNHQRIH-TGEKPYRCIECGKAFSQKSQLIN 728
Query: 662 HLRRHSRRRS 671
H R H+ ++S
Sbjct: 729 HQRTHTVKKS 738
Score = 164 bits (414), Expect = 1e-39
Identities = 156/577 (27%), Positives = 230/577 (39%), Gaps = 124/577 (21%)
Query: 10 CSDCQRHFPSLPELSRHREL--------------LHPSPNQ--DSEEADSIPRPYRCQQC 53
CS+C++ F P L +H+ P +Q + +PY C QC
Sbjct: 209 CSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQC 268
Query: 54 GRGYRHPGSLVNHRRTHETGLFP--CTTCGKDFSNPMALKSHMRTHAPE--------GR- 102
G+ + L +H+RTH TG P C CGK FS L SH RTH E GR
Sbjct: 269 GKAFSQKSQLTSHQRTH-TGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRA 327
Query: 103 -----------RRHRPPRPKEA-------------TPHLQGETVS-----TDSWGQRLGS 133
R H +P E H + T + +D
Sbjct: 328 FSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEK 387
Query: 134 SEGWENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGADGWGPSTN 192
SE +QT HT E P +C + R A R+R L +H T+
Sbjct: 388 SELIRHQTIHTGEKPYECS---ECRKA--------FRERSSLINH-----------QRTH 425
Query: 193 SARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGKTYKHAG 252
+ P I S + +L + TG E+ + CS+CGK +
Sbjct: 426 TGEKPHGCIQCGKAFSQ-KSHLISHQMTHTG------------EKPFICSKCGKAFSRKS 472
Query: 253 SLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLE 311
L H+++HT Y C+ C K FS ++L NH R+H +PY C C + F L+
Sbjct: 473 QLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLIS 532
Query: 312 HQQSHEGERQEPRWE------EKGMPTTN--GHTDESSQDQLPSAQMLNGSAELSTSGEL 363
HQ++H GE+ E EK T+ HT E + + + ++L+T +
Sbjct: 533 HQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRI 592
Query: 364 EDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFNAAALKNHVR 421
+P+ C C + + LI H ++H TG Y C+ C K ++L NH R
Sbjct: 593 HTG----EKPYECSLCRKAFFEKSELIRHLRTH-TGEKPYECNECRKAFREKSSLINHQR 647
Query: 422 AH--HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGS 479
H +P + E G+ + L+ + TH E +PY CSEC +A+ +
Sbjct: 648 IHTGEKPFE-CSECGKAFSRKSHLIPHQRTHTGE---------KPYGCSECRKAFSQKSQ 697
Query: 480 LVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVH 514
LVNH+ H TGE Y+C C + + L NH R H
Sbjct: 698 LVNHQRIH-TGEKPYRCIECGKAFSQKSQLINHQRTH 733
Score = 159 bits (401), Expect = 3e-38
Identities = 152/624 (24%), Positives = 242/624 (38%), Gaps = 117/624 (18%)
Query: 786 DSLTGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHTCSDCGHSFPHATGLLSHRPCHP- 844
+ L E +K + +P+ H + + G C +CG +FP + ++H H
Sbjct: 204 EKLYECSECRKRFSKKPSLIKHQSRHIRDIAFG----CGNCGKTFPQKSQFITHHRTHTG 259
Query: 845 PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHRRQAH 904
Y CS C K F L SH + H T +P+ C CG F R + + + H
Sbjct: 260 EKPYNCSQCGKAFSQKSQLTSHQRTH-----TGEKPYECGECGKAF-SRKSHLISHWRTH 313
Query: 905 SSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSAGYGHICGCCG 964
+ + G E A S L + ++ ++ E C CG
Sbjct: 314 TGE----------KPYGCNECGRAFSEKSNLINHQRIHTGEKPFE----------CRECG 353
Query: 965 QTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDIVNSVSGEGGDAKS 1024
+ + L HH++ + GT P G + D +
Sbjct: 354 KAFSRKSQLVTHHRTHT-GT------KPFGCS------------------------DCRK 382
Query: 1025 QEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGD--FLCP 1082
+ L I GE +P+ C++C K +R SL+NH++ H TG+ C
Sbjct: 383 AFFEKSELIRHQTIHTGE-------KPYECSECRKAFRERSSLINHQRTH-TGEKPHGCI 434
Query: 1083 VCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAAGSSELQ-VGPIPEGGSNKPQHMAE 1141
C + + + +H H G +P + A S + Q V KP +E
Sbjct: 435 QCGKAFSQKSHLISHQMTH---TGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSE 491
Query: 1142 EGPGQAEVEKLQEELKVEPLEEVARVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSER 1201
G +E L ++ E+ V E + K I Q + E+
Sbjct: 492 CGKAFSEKLSLTNHQRIHTGEK-PYVCSECGKAFCQKSHLISH---------QRTHTGEK 541
Query: 1202 PFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPRRFR 1259
P+ C CG+++ SL H+++H TG + C+ C K FS L H+RIH + +
Sbjct: 542 PYECSECGKAFGEKSSLATHQRTH-TGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYE 600
Query: 1260 CSECGKAFRLRKQLASHQRVHMERR--GGGGTRKATRE-------------DRPFRCGQC 1304
CS C KAF + +L H R H + RKA RE ++PF C +C
Sbjct: 601 CSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSEC 660
Query: 1305 GRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRT 1362
G+ + L+ H+R+H TG+ Y C C K +S + L +HQR+H+ +
Sbjct: 661 GKAFSRKSHLIPHQRTH-TGEKPYGCSECRKAFSQKSQLVNHQRIHTGEK---------- 709
Query: 1363 AVRCALCGRSFPGRGSLERHLREH 1386
RC CG++F + L H R H
Sbjct: 710 PYRCIECGKAFSQKSQLINHQRTH 733
Score = 129 bits (324), Expect = 3e-29
Identities = 83/257 (32%), Positives = 108/257 (42%), Gaps = 12/257 (4%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C CGKT+ Q + H+ T + C C K F SH H + + C +C
Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPR 1650
GKAF L SH + H + A K+ Q + G E P E R
Sbjct: 297 GKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTG-----EKPFEC-R 350
Query: 1651 GPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLC 1709
G++ +R Q VT +PF C+ C +++ L+ HQ HT Y CS C
Sbjct: 351 ECGKAF--SRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSEC 408
Query: 1710 PKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRH 1769
K SL NH RTHT K H C CGKAF + L H H E PF C C +
Sbjct: 409 RKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHT-GEKPFICSKCGKA 467
Query: 1770 FRRRISFVQHQQQHQEE 1786
F R+ V+HQ+ H E
Sbjct: 468 FSRKSQLVRHQRTHTGE 484
Score = 129 bits (324), Expect = 3e-29
Identities = 87/295 (29%), Positives = 126/295 (42%), Gaps = 21/295 (7%)
Query: 1497 PCHAGDCQLNGPTLSHMDS-WDNRDNSSQLQPGSHSSCSQCGKTYCQSGSLLNHNTNKTD 1555
P G+C SH+ S W R ++ + G C++CG+ + + +L+NH T
Sbjct: 290 PYECGECGKAFSRKSHLISHW--RTHTGEKPYG----CNECGRAFSEKSNLINHQRIHTG 343
Query: 1556 RH--YCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQ 1613
C C K F +H H + F C DC KAF EL H H +
Sbjct: 344 EKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHT---GE 400
Query: 1614 VPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVER-ARGGQAVTSMAAED 1672
P + E R KA ++ + E P G + + ++ ++
Sbjct: 401 KPYECSECR--KAFRERSSLI----NHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHT 454
Query: 1673 KERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKR 1731
E+PF C++CG+++ L+ HQ+ HT Y CS C K LSL NH R HT K
Sbjct: 455 GEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKP 514
Query: 1732 HCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
+ CS CGKAF + L H R H E P+ C C + F + S HQ+ H E
Sbjct: 515 YVCSECGKAFCQKSHLISHQRTHT-GEKPYECSECGKAFGEKSSLATHQRTHTGE 568
Score = 129 bits (323), Expect = 3e-29
Identities = 85/277 (30%), Positives = 115/277 (41%), Gaps = 24/277 (8%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
CS+C K + + SL+NH T H C+ C K F SH H + F C C
Sbjct: 405 CSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKC 464
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAG--------TGEDQVVLPGQGKA- 1641
GKAF +L H + H ++ +A K TGE V GKA
Sbjct: 465 GKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAF 524
Query: 1642 -------QEAPSETPRGPGESVERARGGQAVTSMAAEDK----ERPFRCTQCGRSYRHAG 1690
+ T P E E + +S+A + E+P+ C C +++
Sbjct: 525 CQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKS 584
Query: 1691 SLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEG 1749
L HQ+ HT Y CSLC K L H RTHT K + C+ C KAFR + L
Sbjct: 585 QLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLIN 644
Query: 1750 HGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
H R+H E PF C C + F R+ + HQ+ H E
Sbjct: 645 HQRIHT-GEKPFECSECGKAFSRKSHLIPHQRTHTGE 680
Score = 124 bits (310), Expect = 1e-27
Identities = 158/692 (22%), Positives = 259/692 (37%), Gaps = 132/692 (19%)
Query: 604 NSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGDFSCGACAKHFHTMAAMKNHL 663
+S+ E T + + + C +SY+ S +I HR + C C K F ++ H
Sbjct: 167 HSKPEDTDTWLKYYDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKH- 225
Query: 664 RRHSRRRSRRHRKRAGGASGGREAKLLAAESWTRELEDNEGLESPQDPSGESPHGAEGNL 723
+SR R A G G K +S + + + +GE P+
Sbjct: 226 ------QSRHIRDIAFGC--GNCGKTFPQKS--------QFITHHRTHTGEKPYNCS--- 266
Query: 724 ESDGDCLQAESEGDKCGLERDETHFQGDK--ESGGTGEGLERKDASLLDNLDIPGEEGGG 781
C +A S+ K L + G+K E G G+ RK + GE+ G
Sbjct: 267 ----QCGKAFSQ--KSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYG 320
Query: 782 THFCDSLTGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHTCSDCGHSFPHATGLLSHRP 841
+ C A + ++ + TG + C +CG +F + L++H
Sbjct: 321 CNECGR----------AFSEKSNLINHQRIHTGEKP---FECRECGKAFSRKSQLVTHHR 367
Query: 842 CHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHR 900
H + CS C K F L H H T +P+ C C F R+ H+
Sbjct: 368 THTGTKPFGCSDCRKAFFEKSELIRHQTIH-----TGEKPYECSECRKAFRERSSLINHQ 422
Query: 901 RQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSAGYGHIC 960
R H+ + G + A S L ++ + ++ IC
Sbjct: 423 R-THTGE----------KPHGCIQCGKAFSQKSHLISHQMTHTGEKPF----------IC 461
Query: 961 GCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDIVNSVSGEGG 1020
CG+ + L RH ++ + + E G
Sbjct: 462 SKCGKAFSRKSQLVRHQRTHTGEKPYE----------------------------CSECG 493
Query: 1021 DAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGD-- 1078
A S++ L + I GE +P+ C++CGK + L++H++ H TG+
Sbjct: 494 KAFSEK---LSLTNHQRIHTGE-------KPYVCSECGKAFCQKSHLISHQRTH-TGEKP 542
Query: 1079 FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAAGSSELQVGPIPE-GGSNKPQ 1137
+ C C + + ++ H R H G +P E A S + Q+ KP
Sbjct: 543 YECSECGKAFGEKSSLATHQRTHT---GEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPY 599
Query: 1138 HMAEEGPGQAEVEKLQEELKVEPLE---EVARVKEEVWEETTVKGEEIEPRLETAEKGCQ 1194
+ E +L L+ E E ++ E++++ + R+ T EK
Sbjct: 600 ECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQ---RIHTGEK--- 653
Query: 1195 TEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIH 1252
PF C CG+++ LI H+++H TG +GC C K FS L NH+RIH
Sbjct: 654 -------PFECSECGKAFSRKSHLIPHQRTH-TGEKPYGCSECRKAFSQKSQLVNHQRIH 705
Query: 1253 ADPRRFRCSECGKAFRLRKQLASHQRVHMERR 1284
+ +RC ECGKAF + QL +HQR H ++
Sbjct: 706 TGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737
Score = 123 bits (308), Expect = 2e-27
Identities = 77/259 (29%), Positives = 114/259 (44%), Gaps = 14/259 (5%)
Query: 1532 SCSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPD 1589
+CSQCGK + Q L +H T + C C K F SH H + + C +
Sbjct: 264 NCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNE 323
Query: 1590 CGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETP 1649
CG+AF L +H + H + P + E KA + + Q+V + P
Sbjct: 324 CGRAFSEKSNLINHQRIHT---GEKPFECREC--GKAFSRKSQLVTHHRTHTGTKPFGCS 378
Query: 1650 RGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGLYP--CS 1707
E++ + + E+P+ C++C +++R SL+NHQ+ H TG P C
Sbjct: 379 DCRKAFFEKS---ELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTH-TGEKPHGCI 434
Query: 1708 LCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCP 1767
C K L +H THT K CS CGKAF ++L H R H E P+ C C
Sbjct: 435 QCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHT-GEKPYECSECG 493
Query: 1768 RHFRRRISFVQHQQQHQEE 1786
+ F ++S HQ+ H E
Sbjct: 494 KAFSEKLSLTNHQRIHTGE 512
Score = 113 bits (283), Expect = 1e-24
Identities = 73/257 (28%), Positives = 108/257 (42%), Gaps = 13/257 (5%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDRHY-CLLCSKEFLNPVATKSHSHNHIDAQTFACPDCG 1591
C + ++Y +S ++ H ++ Y C C K F + H HI F C +CG
Sbjct: 182 CDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCG 241
Query: 1592 KAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRG 1651
K F + +H + H +Q +A K+ Q G E P
Sbjct: 242 KTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTG---------EKPYE 292
Query: 1652 PGESVER-ARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLC 1709
GE + +R ++ E+P+ C +CGR++ +L+NHQ+ HT + C C
Sbjct: 293 CGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECREC 352
Query: 1710 PKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRH 1769
K L H RTHT K CS C KAF + L H +H E P+ C C +
Sbjct: 353 GKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHT-GEKPYECSECRKA 411
Query: 1770 FRRRISFVQHQQQHQEE 1786
FR R S + HQ+ H E
Sbjct: 412 FRERSSLINHQRTHTGE 428
Score = 111 bits (277), Expect = 7e-24
Identities = 66/229 (28%), Positives = 101/229 (44%), Gaps = 11/229 (4%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
CS+CGK +CQ L++H T + C C K F + +H H + + C DC
Sbjct: 517 CSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDC 576
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPR 1650
KAF +L +H + H + P + R KA + +++ + E P E
Sbjct: 577 EKAFSQKSQLNTHQRIHT---GEKPYECSLCR--KAFFEKSELIRHLRTHTGEKPYECNE 631
Query: 1651 GPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLC 1709
E++ + E+PF C++CG+++ L+ HQ+ HT Y CS C
Sbjct: 632 CRKAFREKS---SLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSEC 688
Query: 1710 PKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPRE 1758
K L NH R HT K + C CGKAF ++L H R H ++
Sbjct: 689 RKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737
Score = 58.9 bits (141), Expect = 4e-08
Identities = 38/138 (27%), Positives = 57/138 (41%), Gaps = 29/138 (21%)
Query: 1677 FRCTQCGRSYRHAGSLLNHQKAHTTGLYPCSLCPKLL---PNLLSLKN------------ 1721
+ C + SY+ + ++ H+ LY CS C K P+L+ ++
Sbjct: 180 YDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGN 239
Query: 1722 -------------HSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPR 1768
H RTHT K + CS CGKAF ++L H R H E P+ C C +
Sbjct: 240 CGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHT-GEKPYECGECGK 298
Query: 1769 HFRRRISFVQHQQQHQEE 1786
F R+ + H + H E
Sbjct: 299 AFSRKSHLISHWRTHTGE 316
>gi|188497653 zinc finger protein 84 [Homo sapiens]
Length = 738
Score = 196 bits (499), Expect = 1e-49
Identities = 160/612 (26%), Positives = 234/612 (38%), Gaps = 110/612 (17%)
Query: 1200 ERPFSCEVCGRSYKHAGSLINHRQSH-QTGHFGCQACSKGFSNLMSLKNHRRIHADPRRF 1258
E+ + C C + + SLI H+ H + FGC C K F H R H + +
Sbjct: 204 EKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPY 263
Query: 1259 RCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHR 1318
CS+CGKAF + QL SHQR H ++P+ CG+CG+ + L++H
Sbjct: 264 NCSQCGKAFSQKSQLTSHQRTH-------------TGEKPYECGECGKAFSRKSHLISHW 310
Query: 1319 RSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGR 1376
R+H TG+ Y C C + +S + L +HQR+H+ + C CG++F +
Sbjct: 311 RTH-TGEKPYGCNECGRAFSEKSNLINHQRIHTGEK----------PFECRECGKAFSRK 359
Query: 1377 GSLERHLREHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRP 1436
L H R H T+ G ++ L Q + T G +P E R
Sbjct: 360 SQLVTHHRTHTGTK---PFGCSDCRKAFFEKSELIRHQTIHT---GEKP---YECSECRK 410
Query: 1437 GERSQSPI----RAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEP--- 1489
R +S + R + E P G G S Q E+P
Sbjct: 411 AFRERSSLINHQRTHTGEKPH---------GCIQCGKAFSQKSHLISHQMTHTGEKPFIC 461
Query: 1490 ----------EDSVHRSPCHAG----DCQLNGPTLSHMDSWDNRDN-SSQLQPGSHSSCS 1534
V H G +C G S S N + +P S C
Sbjct: 462 SKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSEC- 520
Query: 1535 QCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGK 1592
GK +CQ L++H T + C C K F + +H H + + C DC K
Sbjct: 521 --GKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEK 578
Query: 1593 AFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGP 1652
AF +L +H + H TGE KA SE
Sbjct: 579 AFSQKSQLNTHQRIH--------------------TGEKPYECSLCRKAFFEKSE----- 613
Query: 1653 GESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLCPK 1711
+ + E+P+ C +C +++R SL+NHQ+ HT + CS C K
Sbjct: 614 -----------LIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSECGK 662
Query: 1712 LLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFR 1771
L H RTHT K + CS C KAF ++L H R+H E P+ C C + F
Sbjct: 663 AFSRKSHLIPHQRTHTGEKPYGCSECRKAFSQKSQLVNHQRIHT-GEKPYRCIECGKAFS 721
Query: 1772 RRISFVQHQQQH 1783
++ + HQ+ H
Sbjct: 722 QKSQLINHQRTH 733
Score = 169 bits (429), Expect = 2e-41
Identities = 166/670 (24%), Positives = 256/670 (38%), Gaps = 125/670 (18%)
Query: 30 LHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRTHETGLFPCTTCGKDFSNPMA 89
LH P E+ D+ + Y C + Y+ ++ HR L+ C+ C K FS
Sbjct: 166 LHSKP----EDTDTWLKYYDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSK--- 218
Query: 90 LKSHMRTHAPEGRRRHRPPRPKEATPHLQGETVSTDSWGQRLGS-SEGWENQTKHTEETP 148
+P K + H++ + G+ S+ + HT E P
Sbjct: 219 ----------------KPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKP 262
Query: 149 -DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGADGWGPSTNSARAPPLPIPASSLL 207
+C +A S Q+ L SH G P
Sbjct: 263 YNCSQCG--KAFS---------QKSQLTSHQRTHTGEK------------PYECGECGKA 299
Query: 208 SNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSHTLGIYP 267
+ + +L TG E+ Y C++CG+ + +L NH++ HT G P
Sbjct: 300 FSRKSHLISHWRTHTG------------EKPYGCNECGRAFSEKSNLINHQRIHT-GEKP 346
Query: 268 --CAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGE------ 319
C C K FS L H R H +P+ C C + F EL+ HQ H GE
Sbjct: 347 FECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECS 406
Query: 320 --RQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCG 377
R+ R + HT E + + + + L S ++ +G +PF C
Sbjct: 407 ECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHL-ISHQMTHTG---EKPFICS 462
Query: 378 DCGRTYRHAGSLINHRKSHQTGV--YPCSLCSKQLFNAAALKNHVRAHHRPRQGV-GENG 434
CG+ + L+ H+++H TG Y CS C K +L NH R H + V E G
Sbjct: 463 KCGKAFSRKSQLVRHQRTH-TGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECG 521
Query: 435 QPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--Y 492
+ + L+ + TH E +PY+CSECG+A+ + SL H+ +H TGE Y
Sbjct: 522 KAFCQKSHLISHQRTHTGE---------KPYECSECGKAFGEKSSLATHQRTH-TGEKPY 571
Query: 493 QCSLCPRKYPNLMALRNHVRVH-------CKAARRSADIGAEGAPSHLKVELPPDPVEAE 545
+C C + + L H R+H C R++ +E HL+ P E
Sbjct: 572 ECRDCEKAFSQKSQLNTHQRIHTGEKPYECSLCRKAFFEKSE-LIRHLRTHTGEKPYECN 630
Query: 546 AAPHT--DQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKE 603
++ + H+ T P CS CG F L H TH GEK
Sbjct: 631 ECRKAFREKSSLINHQRIHTGEKPFE-------CSECGKAFSRKSHLIPHQRTH-TGEKP 682
Query: 604 NSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKN 661
+ C +C K++ L+NH++ H TG+ + C C K F + + N
Sbjct: 683 -------------YGCSECRKAFSQKSQLVNHQRIH-TGEKPYRCIECGKAFSQKSQLIN 728
Query: 662 HLRRHSRRRS 671
H R H+ ++S
Sbjct: 729 HQRTHTVKKS 738
Score = 164 bits (414), Expect = 1e-39
Identities = 156/577 (27%), Positives = 230/577 (39%), Gaps = 124/577 (21%)
Query: 10 CSDCQRHFPSLPELSRHREL--------------LHPSPNQ--DSEEADSIPRPYRCQQC 53
CS+C++ F P L +H+ P +Q + +PY C QC
Sbjct: 209 CSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCGKTFPQKSQFITHHRTHTGEKPYNCSQC 268
Query: 54 GRGYRHPGSLVNHRRTHETGLFP--CTTCGKDFSNPMALKSHMRTHAPE--------GR- 102
G+ + L +H+RTH TG P C CGK FS L SH RTH E GR
Sbjct: 269 GKAFSQKSQLTSHQRTH-TGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRA 327
Query: 103 -----------RRHRPPRPKEA-------------TPHLQGETVS-----TDSWGQRLGS 133
R H +P E H + T + +D
Sbjct: 328 FSEKSNLINHQRIHTGEKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEK 387
Query: 134 SEGWENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGADGWGPSTN 192
SE +QT HT E P +C + R A R+R L +H T+
Sbjct: 388 SELIRHQTIHTGEKPYECS---ECRKA--------FRERSSLINH-----------QRTH 425
Query: 193 SARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGKTYKHAG 252
+ P I S + +L + TG E+ + CS+CGK +
Sbjct: 426 TGEKPHGCIQCGKAFSQ-KSHLISHQMTHTG------------EKPFICSKCGKAFSRKS 472
Query: 253 SLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLE 311
L H+++HT Y C+ C K FS ++L NH R+H +PY C C + F L+
Sbjct: 473 QLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAFCQKSHLIS 532
Query: 312 HQQSHEGERQEPRWE------EKGMPTTN--GHTDESSQDQLPSAQMLNGSAELSTSGEL 363
HQ++H GE+ E EK T+ HT E + + + ++L+T +
Sbjct: 533 HQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKSQLNTHQRI 592
Query: 364 EDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFNAAALKNHVR 421
+P+ C C + + LI H ++H TG Y C+ C K ++L NH R
Sbjct: 593 HTG----EKPYECSLCRKAFFEKSELIRHLRTH-TGEKPYECNECRKAFREKSSLINHQR 647
Query: 422 AH--HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGS 479
H +P + E G+ + L+ + TH E +PY CSEC +A+ +
Sbjct: 648 IHTGEKPFE-CSECGKAFSRKSHLIPHQRTHTGE---------KPYGCSECRKAFSQKSQ 697
Query: 480 LVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVH 514
LVNH+ H TGE Y+C C + + L NH R H
Sbjct: 698 LVNHQRIH-TGEKPYRCIECGKAFSQKSQLINHQRTH 733
Score = 159 bits (401), Expect = 3e-38
Identities = 152/624 (24%), Positives = 242/624 (38%), Gaps = 117/624 (18%)
Query: 786 DSLTGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHTCSDCGHSFPHATGLLSHRPCHP- 844
+ L E +K + +P+ H + + G C +CG +FP + ++H H
Sbjct: 204 EKLYECSECRKRFSKKPSLIKHQSRHIRDIAFG----CGNCGKTFPQKSQFITHHRTHTG 259
Query: 845 PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHRRQAH 904
Y CS C K F L SH + H T +P+ C CG F R + + + H
Sbjct: 260 EKPYNCSQCGKAFSQKSQLTSHQRTH-----TGEKPYECGECGKAF-SRKSHLISHWRTH 313
Query: 905 SSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSAGYGHICGCCG 964
+ + G E A S L + ++ ++ E C CG
Sbjct: 314 TGE----------KPYGCNECGRAFSEKSNLINHQRIHTGEKPFE----------CRECG 353
Query: 965 QTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDIVNSVSGEGGDAKS 1024
+ + L HH++ + GT P G + D +
Sbjct: 354 KAFSRKSQLVTHHRTHT-GT------KPFGCS------------------------DCRK 382
Query: 1025 QEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGD--FLCP 1082
+ L I GE +P+ C++C K +R SL+NH++ H TG+ C
Sbjct: 383 AFFEKSELIRHQTIHTGE-------KPYECSECRKAFRERSSLINHQRTH-TGEKPHGCI 434
Query: 1083 VCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAAGSSELQ-VGPIPEGGSNKPQHMAE 1141
C + + + +H H G +P + A S + Q V KP +E
Sbjct: 435 QCGKAFSQKSHLISHQMTH---TGEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSE 491
Query: 1142 EGPGQAEVEKLQEELKVEPLEEVARVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSER 1201
G +E L ++ E+ V E + K I Q + E+
Sbjct: 492 CGKAFSEKLSLTNHQRIHTGEK-PYVCSECGKAFCQKSHLISH---------QRTHTGEK 541
Query: 1202 PFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPRRFR 1259
P+ C CG+++ SL H+++H TG + C+ C K FS L H+RIH + +
Sbjct: 542 PYECSECGKAFGEKSSLATHQRTH-TGEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPYE 600
Query: 1260 CSECGKAFRLRKQLASHQRVHMERR--GGGGTRKATRE-------------DRPFRCGQC 1304
CS C KAF + +L H R H + RKA RE ++PF C +C
Sbjct: 601 CSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQRIHTGEKPFECSEC 660
Query: 1305 GRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRT 1362
G+ + L+ H+R+H TG+ Y C C K +S + L +HQR+H+ +
Sbjct: 661 GKAFSRKSHLIPHQRTH-TGEKPYGCSECRKAFSQKSQLVNHQRIHTGEK---------- 709
Query: 1363 AVRCALCGRSFPGRGSLERHLREH 1386
RC CG++F + L H R H
Sbjct: 710 PYRCIECGKAFSQKSQLINHQRTH 733
Score = 129 bits (324), Expect = 3e-29
Identities = 83/257 (32%), Positives = 108/257 (42%), Gaps = 12/257 (4%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C CGKT+ Q + H+ T + C C K F SH H + + C +C
Sbjct: 237 CGNCGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTGEKPYECGEC 296
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPR 1650
GKAF L SH + H + A K+ Q + G E P E R
Sbjct: 297 GKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTG-----EKPFEC-R 350
Query: 1651 GPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLC 1709
G++ +R Q VT +PF C+ C +++ L+ HQ HT Y CS C
Sbjct: 351 ECGKAF--SRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHTGEKPYECSEC 408
Query: 1710 PKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRH 1769
K SL NH RTHT K H C CGKAF + L H H E PF C C +
Sbjct: 409 RKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHT-GEKPFICSKCGKA 467
Query: 1770 FRRRISFVQHQQQHQEE 1786
F R+ V+HQ+ H E
Sbjct: 468 FSRKSQLVRHQRTHTGE 484
Score = 129 bits (324), Expect = 3e-29
Identities = 87/295 (29%), Positives = 126/295 (42%), Gaps = 21/295 (7%)
Query: 1497 PCHAGDCQLNGPTLSHMDS-WDNRDNSSQLQPGSHSSCSQCGKTYCQSGSLLNHNTNKTD 1555
P G+C SH+ S W R ++ + G C++CG+ + + +L+NH T
Sbjct: 290 PYECGECGKAFSRKSHLISHW--RTHTGEKPYG----CNECGRAFSEKSNLINHQRIHTG 343
Query: 1556 RH--YCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQ 1613
C C K F +H H + F C DC KAF EL H H +
Sbjct: 344 EKPFECRECGKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHT---GE 400
Query: 1614 VPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVER-ARGGQAVTSMAAED 1672
P + E R KA ++ + E P G + + ++ ++
Sbjct: 401 KPYECSECR--KAFRERSSLI----NHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHT 454
Query: 1673 KERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKR 1731
E+PF C++CG+++ L+ HQ+ HT Y CS C K LSL NH R HT K
Sbjct: 455 GEKPFICSKCGKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKP 514
Query: 1732 HCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
+ CS CGKAF + L H R H E P+ C C + F + S HQ+ H E
Sbjct: 515 YVCSECGKAFCQKSHLISHQRTHT-GEKPYECSECGKAFGEKSSLATHQRTHTGE 568
Score = 129 bits (323), Expect = 3e-29
Identities = 85/277 (30%), Positives = 115/277 (41%), Gaps = 24/277 (8%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
CS+C K + + SL+NH T H C+ C K F SH H + F C C
Sbjct: 405 CSECRKAFRERSSLINHQRTHTGEKPHGCIQCGKAFSQKSHLISHQMTHTGEKPFICSKC 464
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAG--------TGEDQVVLPGQGKA- 1641
GKAF +L H + H ++ +A K TGE V GKA
Sbjct: 465 GKAFSRKSQLVRHQRTHTGEKPYECSECGKAFSEKLSLTNHQRIHTGEKPYVCSECGKAF 524
Query: 1642 -------QEAPSETPRGPGESVERARGGQAVTSMAAEDK----ERPFRCTQCGRSYRHAG 1690
+ T P E E + +S+A + E+P+ C C +++
Sbjct: 525 CQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDCEKAFSQKS 584
Query: 1691 SLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEG 1749
L HQ+ HT Y CSLC K L H RTHT K + C+ C KAFR + L
Sbjct: 585 QLNTHQRIHTGEKPYECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLIN 644
Query: 1750 HGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
H R+H E PF C C + F R+ + HQ+ H E
Sbjct: 645 HQRIHT-GEKPFECSECGKAFSRKSHLIPHQRTHTGE 680
Score = 124 bits (310), Expect = 1e-27
Identities = 158/692 (22%), Positives = 259/692 (37%), Gaps = 132/692 (19%)
Query: 604 NSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGDFSCGACAKHFHTMAAMKNHL 663
+S+ E T + + + C +SY+ S +I HR + C C K F ++ H
Sbjct: 167 HSKPEDTDTWLKYYDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKH- 225
Query: 664 RRHSRRRSRRHRKRAGGASGGREAKLLAAESWTRELEDNEGLESPQDPSGESPHGAEGNL 723
+SR R A G G K +S + + + +GE P+
Sbjct: 226 ------QSRHIRDIAFGC--GNCGKTFPQKS--------QFITHHRTHTGEKPYNCS--- 266
Query: 724 ESDGDCLQAESEGDKCGLERDETHFQGDK--ESGGTGEGLERKDASLLDNLDIPGEEGGG 781
C +A S+ K L + G+K E G G+ RK + GE+ G
Sbjct: 267 ----QCGKAFSQ--KSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYG 320
Query: 782 THFCDSLTGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHTCSDCGHSFPHATGLLSHRP 841
+ C A + ++ + TG + C +CG +F + L++H
Sbjct: 321 CNECGR----------AFSEKSNLINHQRIHTGEKP---FECRECGKAFSRKSQLVTHHR 367
Query: 842 CHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHR 900
H + CS C K F L H H T +P+ C C F R+ H+
Sbjct: 368 THTGTKPFGCSDCRKAFFEKSELIRHQTIH-----TGEKPYECSECRKAFRERSSLINHQ 422
Query: 901 RQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSAGYGHIC 960
R H+ + G + A S L ++ + ++ IC
Sbjct: 423 R-THTGE----------KPHGCIQCGKAFSQKSHLISHQMTHTGEKPF----------IC 461
Query: 961 GCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDIVNSVSGEGG 1020
CG+ + L RH ++ + + E G
Sbjct: 462 SKCGKAFSRKSQLVRHQRTHTGEKPYE----------------------------CSECG 493
Query: 1021 DAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGD-- 1078
A S++ L + I GE +P+ C++CGK + L++H++ H TG+
Sbjct: 494 KAFSEK---LSLTNHQRIHTGE-------KPYVCSECGKAFCQKSHLISHQRTH-TGEKP 542
Query: 1079 FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAAGSSELQVGPIPE-GGSNKPQ 1137
+ C C + + ++ H R H G +P E A S + Q+ KP
Sbjct: 543 YECSECGKAFGEKSSLATHQRTHT---GEKPYECRDCEKAFSQKSQLNTHQRIHTGEKPY 599
Query: 1138 HMAEEGPGQAEVEKLQEELKVEPLE---EVARVKEEVWEETTVKGEEIEPRLETAEKGCQ 1194
+ E +L L+ E E ++ E++++ + R+ T EK
Sbjct: 600 ECSLCRKAFFEKSELIRHLRTHTGEKPYECNECRKAFREKSSLINHQ---RIHTGEK--- 653
Query: 1195 TEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIH 1252
PF C CG+++ LI H+++H TG +GC C K FS L NH+RIH
Sbjct: 654 -------PFECSECGKAFSRKSHLIPHQRTH-TGEKPYGCSECRKAFSQKSQLVNHQRIH 705
Query: 1253 ADPRRFRCSECGKAFRLRKQLASHQRVHMERR 1284
+ +RC ECGKAF + QL +HQR H ++
Sbjct: 706 TGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737
Score = 123 bits (308), Expect = 2e-27
Identities = 77/259 (29%), Positives = 114/259 (44%), Gaps = 14/259 (5%)
Query: 1532 SCSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPD 1589
+CSQCGK + Q L +H T + C C K F SH H + + C +
Sbjct: 264 NCSQCGKAFSQKSQLTSHQRTHTGEKPYECGECGKAFSRKSHLISHWRTHTGEKPYGCNE 323
Query: 1590 CGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETP 1649
CG+AF L +H + H + P + E KA + + Q+V + P
Sbjct: 324 CGRAFSEKSNLINHQRIHT---GEKPFECREC--GKAFSRKSQLVTHHRTHTGTKPFGCS 378
Query: 1650 RGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGLYP--CS 1707
E++ + + E+P+ C++C +++R SL+NHQ+ H TG P C
Sbjct: 379 DCRKAFFEKS---ELIRHQTIHTGEKPYECSECRKAFRERSSLINHQRTH-TGEKPHGCI 434
Query: 1708 LCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCP 1767
C K L +H THT K CS CGKAF ++L H R H E P+ C C
Sbjct: 435 QCGKAFSQKSHLISHQMTHTGEKPFICSKCGKAFSRKSQLVRHQRTHT-GEKPYECSECG 493
Query: 1768 RHFRRRISFVQHQQQHQEE 1786
+ F ++S HQ+ H E
Sbjct: 494 KAFSEKLSLTNHQRIHTGE 512
Score = 113 bits (283), Expect = 1e-24
Identities = 73/257 (28%), Positives = 108/257 (42%), Gaps = 13/257 (5%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDRHY-CLLCSKEFLNPVATKSHSHNHIDAQTFACPDCG 1591
C + ++Y +S ++ H ++ Y C C K F + H HI F C +CG
Sbjct: 182 CDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGNCG 241
Query: 1592 KAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRG 1651
K F + +H + H +Q +A K+ Q G E P
Sbjct: 242 KTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHTG---------EKPYE 292
Query: 1652 PGESVER-ARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLC 1709
GE + +R ++ E+P+ C +CGR++ +L+NHQ+ HT + C C
Sbjct: 293 CGECGKAFSRKSHLISHWRTHTGEKPYGCNECGRAFSEKSNLINHQRIHTGEKPFECREC 352
Query: 1710 PKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRH 1769
K L H RTHT K CS C KAF + L H +H E P+ C C +
Sbjct: 353 GKAFSRKSQLVTHHRTHTGTKPFGCSDCRKAFFEKSELIRHQTIHT-GEKPYECSECRKA 411
Query: 1770 FRRRISFVQHQQQHQEE 1786
FR R S + HQ+ H E
Sbjct: 412 FRERSSLINHQRTHTGE 428
Score = 111 bits (277), Expect = 7e-24
Identities = 66/229 (28%), Positives = 101/229 (44%), Gaps = 11/229 (4%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
CS+CGK +CQ L++H T + C C K F + +H H + + C DC
Sbjct: 517 CSECGKAFCQKSHLISHQRTHTGEKPYECSECGKAFGEKSSLATHQRTHTGEKPYECRDC 576
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPR 1650
KAF +L +H + H + P + R KA + +++ + E P E
Sbjct: 577 EKAFSQKSQLNTHQRIHT---GEKPYECSLCR--KAFFEKSELIRHLRTHTGEKPYECNE 631
Query: 1651 GPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLC 1709
E++ + E+PF C++CG+++ L+ HQ+ HT Y CS C
Sbjct: 632 CRKAFREKS---SLINHQRIHTGEKPFECSECGKAFSRKSHLIPHQRTHTGEKPYGCSEC 688
Query: 1710 PKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPRE 1758
K L NH R HT K + C CGKAF ++L H R H ++
Sbjct: 689 RKAFSQKSQLVNHQRIHTGEKPYRCIECGKAFSQKSQLINHQRTHTVKK 737
Score = 58.9 bits (141), Expect = 4e-08
Identities = 38/138 (27%), Positives = 57/138 (41%), Gaps = 29/138 (21%)
Query: 1677 FRCTQCGRSYRHAGSLLNHQKAHTTGLYPCSLCPKLL---PNLLSLKN------------ 1721
+ C + SY+ + ++ H+ LY CS C K P+L+ ++
Sbjct: 180 YDCDKYKESYKKSQIIIYHRNRLGEKLYECSECRKRFSKKPSLIKHQSRHIRDIAFGCGN 239
Query: 1722 -------------HSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPR 1768
H RTHT K + CS CGKAF ++L H R H E P+ C C +
Sbjct: 240 CGKTFPQKSQFITHHRTHTGEKPYNCSQCGKAFSQKSQLTSHQRTHT-GEKPYECGECGK 298
Query: 1769 HFRRRISFVQHQQQHQEE 1786
F R+ + H + H E
Sbjct: 299 AFSRKSHLISHWRTHTGE 316
>gi|22095393 zinc finger protein 420 [Homo sapiens]
Length = 688
Score = 195 bits (496), Expect = 3e-49
Identities = 161/611 (26%), Positives = 239/611 (39%), Gaps = 98/611 (16%)
Query: 1198 SSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADP 1255
S+E+P+ C+ CG++++ A L H+ H TG + C+ C K FS L H+R+H
Sbjct: 134 STEKPYKCKECGKAFRRASHLTQHQSIH-TGEKPYECKQCGKAFSRDSQLSLHQRLHTGE 192
Query: 1256 RRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLL 1315
+ + C ECGKAF QL H R+H ++P++C +CG+ + + L
Sbjct: 193 KPYACKECGKAFTQSSQLILHHRIHTG-------------EKPYKCEECGKAFIRSSQLT 239
Query: 1316 NHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSF 1373
H++ H TG+ Y C C K ++ L HQRLH+ + C C + F
Sbjct: 240 RHQKVH-TGEKPYECKECGKAFTQNSQLTLHQRLHTGEK----------LYECKECRKVF 288
Query: 1374 PGRGSLERHLREHEETEREPANGQGGLDGTAASEANLTGSQGLETQL--GGAEPVPHLED 1431
L H R H G+ + +A + GSQ + Q G +P E
Sbjct: 289 TQLSQLILHKRIH--------TGEKPYECKECGKAFICGSQLSQHQKIHNGEKPYECKEC 340
Query: 1432 GVPR-PGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPE 1490
G G R + E P GKA + G L H Q + +E+P
Sbjct: 341 GRAFIRGSLLMQHQRIHTGEKPYKCE-ECGKA--FIRGSQLTQH------QRIHTNEKPY 391
Query: 1491 DSVHRSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHS-SCSQCGKTYCQSGSLLNH 1549
+ C+ G SH ++ G C +CGK + + L H
Sbjct: 392 E-----------CKECGKMFSHGSQLTQHQ---RIHTGEKPYQCKECGKAFNRGSLLTRH 437
Query: 1550 NTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAH 1607
T + C C K F H H + + C +CGK+F +L H + H
Sbjct: 438 QRIHTGEKPYECKECGKTFSRGSELTQHERIHTGEKPYECKECGKSFIRGSQLTQHQRIH 497
Query: 1608 ARGHSQVPAQMEEAR-----------DPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESV 1656
+ P + +E R + TGE V GKA
Sbjct: 498 T---GEKPYECKECRMAFTQSSHLSQHQRLHTGEKPYVCNECGKAF-------------- 540
Query: 1657 ERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPN 1715
ARG + E+P++C +CG+++ L HQ+ HT Y C C K +
Sbjct: 541 --ARGLLLIQHQRIHTGEKPYQCKECGKAFIRGSQLTQHQRIHTGEKPYECKECGKAFSH 598
Query: 1716 LLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRIS 1775
L H R HT K + C C KAF ++ L H R+H E P+ C C + F R
Sbjct: 599 GSQLTLHQRIHTGEKPYECRECRKAFTQSSHLSRHQRIHTG-EKPYQCKECGKAFTRGSQ 657
Query: 1776 FVQHQQQHQEE 1786
QHQ+ H E
Sbjct: 658 LTQHQRIHISE 668
Score = 157 bits (397), Expect = 9e-38
Identities = 181/775 (23%), Positives = 293/775 (37%), Gaps = 132/775 (17%)
Query: 945 QREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVV 1004
Q E E LDSA + Y +L SL+ + S + +K ++ M +
Sbjct: 17 QEEWECLDSAQRDLYRDVMLENYSNLVSLDLPSRCASKDLSPEKNTYETELSQWEMSDRL 76
Query: 1005 DSVLEDIVNS---VSGEGGDAKSQEGA------GTPLGDSLCIQGGESLLEAQPR----- 1050
++ + NS + +G K QE G + D + I + L R
Sbjct: 77 ENCDLEESNSRDYLEAKGKMEKQQENQKEYFRQGMIIYDKMSIFNQHTYLSQHSRCHSTE 136
Query: 1051 -PFRCNQCGKTYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGS 1107
P++C +CGK +R L H+ IH TG+ + C C + + + H R H
Sbjct: 137 KPYKCKECGKAFRRASHLTQHQSIH-TGEKPYECKQCGKAFSRDSQLSLHQRLHT----- 190
Query: 1108 EPQVGPIPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARV 1167
KP E G + +L ++ E+ +
Sbjct: 191 -------------------------GEKPYACKECGKAFTQSSQLILHHRIHTGEKPYKC 225
Query: 1168 KEEVWEETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQT 1227
+E + ++ ++ Q + E+P+ C+ CG+++ L H++ H T
Sbjct: 226 EE--CGKAFIRSSQLTRH--------QKVHTGEKPYECKECGKAFTQNSQLTLHQRLH-T 274
Query: 1228 GH--FGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRG 1285
G + C+ C K F+ L L H+RIH + + C ECGKAF QL+ HQ++H
Sbjct: 275 GEKLYECKECRKVFTQLSQLILHKRIHTGEKPYECKECGKAFICGSQLSQHQKIH----- 329
Query: 1286 GGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKD 1343
++P+ C +CGR + L+ H+R H TG+ Y C C K + L
Sbjct: 330 --------NGEKPYECKECGRAFIRGSLLMQHQRIH-TGEKPYKCEECGKAFIRGSQLTQ 380
Query: 1344 HQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGT 1403
HQR+H+ + C CG+ F L +H R H T +P Q G
Sbjct: 381 HQRIHTNEK----------PYECKECGKMFSHGSQLTQHQRIH--TGEKPY--QCKECGK 426
Query: 1404 AASEANL-TGSQGLETQLGGAEPVPHLEDG--VPRPGERSQSPIRAASSEAPEPLSWGAG 1460
A + +L T Q + T G +P E G R E +Q R + E P G
Sbjct: 427 AFNRGSLLTRHQRIHT---GEKPYECKECGKTFSRGSELTQHE-RIHTGEKPYECK-ECG 481
Query: 1461 KAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSPCHAGDCQLNGPTLSHMDSWDNRD 1520
K+ + G L H Q + E+P + +C++ SH+
Sbjct: 482 KS--FIRGSQLTQH------QRIHTGEKPYE--------CKECRMAFTQSSHLSQ----- 520
Query: 1521 NSSQLQPGSHSS-CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSH 1577
+L G C++CGK + + L+ H T + C C K F+ H
Sbjct: 521 -HQRLHTGEKPYVCNECGKAFARGLLLIQHQRIHTGEKPYQCKECGKAFIRGSQLTQHQR 579
Query: 1578 NHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPG 1637
H + + C +CGKAF +L H + H + P + E R KA T +
Sbjct: 580 IHTGEKPYECKECGKAFSHGSQLTLHQRIHT---GEKPYECRECR--KAFTQSSHLSRHQ 634
Query: 1638 QGKAQEAPSETPRGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSL 1692
+ E P + + G++ RG Q E+ F +CG + H +
Sbjct: 635 RIHTGEKPYQC-KECGKAF--TRGSQLTQHQRIHISEKSFEYKECGIDFSHGSQV 686
Score = 155 bits (391), Expect = 4e-37
Identities = 139/575 (24%), Positives = 223/575 (38%), Gaps = 113/575 (19%)
Query: 821 HTCSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQ 879
+ C +CG +F ++ L+ H H Y+C C K F L H + H T +
Sbjct: 195 YACKECGKAFTQSSQLILHHRIHTGEKPYKCEECGKAFIRSSQLTRHQKVH-----TGEK 249
Query: 880 PFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAE 939
P+ C CG F + LH+R H+ + E E R QLS+
Sbjct: 250 PYECKECGKAFTQNSQLTLHQR-LHTGEKLYECKE-------------CRKVFTQLSQLI 295
Query: 940 LLNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDA 999
L ++ + + C CG+ + GS HQ +G + P G A
Sbjct: 296 LHKRIHTGEKPYE-------CKECGKAFI-CGSQLSQHQKIHNG----EKPYECKECGRA 343
Query: 1000 MEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGK 1059
+ S+L +GE + G G L + +P+ C +CGK
Sbjct: 344 F--IRGSLLMQHQRIHTGEKPYKCEECGKAFIRGSQLT---QHQRIHTNEKPYECKECGK 398
Query: 1060 TYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEA 1117
+ HG L H++IH TG+ + C C + + + H R H
Sbjct: 399 MFSHGSQLTQHQRIH-TGEKPYQCKECGKAFNRGSLLTRHQRIHT--------------- 442
Query: 1118 AGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKEEVWEETTV 1177
KP E G + +L + ++ E+ KE ++ +
Sbjct: 443 ---------------GEKPYECKECGKTFSRGSELTQHERIHTGEKPYECKE--CGKSFI 485
Query: 1178 KGEEI--EPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQ 1233
+G ++ R+ T EK P+ C+ C ++ + L H++ H TG + C
Sbjct: 486 RGSQLTQHQRIHTGEK----------PYECKECRMAFTQSSHLSQHQRLH-TGEKPYVCN 534
Query: 1234 ACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKAT 1293
C K F+ + L H+RIH + ++C ECGKAF QL HQR+H
Sbjct: 535 ECGKAFARGLLLIQHQRIHTGEKPYQCKECGKAFIRGSQLTQHQRIHTG----------- 583
Query: 1294 REDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSEN 1351
++P+ C +CG+ + H L H+R H TG+ Y C C K ++ L HQR+H+
Sbjct: 584 --EKPYECKECGKAFSHGSQLTLHQRIH-TGEKPYECRECRKAFTQSSHLSRHQRIHTGE 640
Query: 1352 RRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREH 1386
+ +C CG++F L +H R H
Sbjct: 641 K----------PYQCKECGKAFTRGSQLTQHQRIH 665
Score = 153 bits (387), Expect = 1e-36
Identities = 128/468 (27%), Positives = 193/468 (41%), Gaps = 87/468 (18%)
Query: 236 ERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPY 294
E+ YKC +CGK + + LT H++ HT Y C C K F+ L H RLH + Y
Sbjct: 220 EKPYKCEECGKAFIRSSQLTRHQKVHTGEKPYECKECGKAFTQNSQLTLHQRLHTGEKLY 279
Query: 295 HCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGS 354
C C +VF +L+ H++ H GE+ +E G G QL Q ++
Sbjct: 280 ECKECRKVFTQLSQLILHKRIHTGEKPY-ECKECGKAFICG-------SQLSQHQKIH-- 329
Query: 355 AELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTGV--YPCSLCSKQLFN 412
+GE +P+ C +CGR + L+ H++ H TG Y C C K
Sbjct: 330 -----NGE---------KPYECKECGRAFIRGSLLMQHQRIH-TGEKPYKCEECGKAFIR 374
Query: 413 AAALKNHVRAHHRPRQ-GVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECG 471
+ L H R H + E G+ + L + H E +PY+C ECG
Sbjct: 375 GSQLTQHQRIHTNEKPYECKECGKMFSHGSQLTQHQRIHTGE---------KPYQCKECG 425
Query: 472 RAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVH-------CKAARRSA 522
+A+ +RGSL+ TGE Y+C C + + L H R+H CK +S
Sbjct: 426 KAF-NRGSLLTRHQRIHTGEKPYECKECGKTFSRGSELTQHERIHTGEKPYECKECGKSF 484
Query: 523 DIGAEGAPSHLKVELPPDPVEAEAA--PHTDQDHVCKHEEEATDITPAADKTAAHICSIC 580
G++ H ++ P E + T H+ +H+ T P ++C+ C
Sbjct: 485 IRGSQ-LTQHQRIHTGEKPYECKECRMAFTQSSHLSQHQRLHTGEKP-------YVCNEC 536
Query: 581 GLLFEDAESLERHGLTHGAGEK------------------ENSRTETTMSPPRAFACRDC 622
G F L +H H GEK ++ R T P + C++C
Sbjct: 537 GKAFARGLLLIQHQRIH-TGEKPYQCKECGKAFIRGSQLTQHQRIHTGEKP---YECKEC 592
Query: 623 GKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHSR 668
GK++ H L H++ H TG+ + C C K F +HL RH R
Sbjct: 593 GKAFSHGSQLTLHQRIH-TGEKPYECRECRKAF----TQSSHLSRHQR 635
Score = 133 bits (334), Expect = 2e-30
Identities = 113/458 (24%), Positives = 181/458 (39%), Gaps = 94/458 (20%)
Query: 236 ERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPY 294
E+ Y+C +CGK + LT H++ HT +Y C C K F+ L L H R+H +PY
Sbjct: 248 EKPYECKECGKAFTQNSQLTLHQRLHTGEKLYECKECRKVFTQLSQLILHKRIHTGEKPY 307
Query: 295 HCPHCPRVFRLPRELLEHQQSHEGER--------------------------QEP-RWEE 327
C C + F +L +HQ+ H GE+ ++P + EE
Sbjct: 308 ECKECGKAFICGSQLSQHQKIHNGEKPYECKECGRAFIRGSLLMQHQRIHTGEKPYKCEE 367
Query: 328 KGMPTTNG---------HTDESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCGD 378
G G HT+E + +M + ++L+ + +P++C +
Sbjct: 368 CGKAFIRGSQLTQHQRIHTNEKPYECKECGKMFSHGSQLTQHQRIHTGE----KPYQCKE 423
Query: 379 CGRTYRHAGSLINHRKSHQTGV--YPCSLCSKQLFNAAALKNHVRAH--HRPRQGVGENG 434
CG+ + L H++ H TG Y C C K + L H R H +P + E G
Sbjct: 424 CGKAFNRGSLLTRHQRIH-TGEKPYECKECGKTFSRGSELTQHERIHTGEKPYE-CKECG 481
Query: 435 QPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--Y 492
+ + + L + H E +PY+C EC A+ L H+ H TGE Y
Sbjct: 482 KSFIRGSQLTQHQRIHTGE---------KPYECKECRMAFTQSSHLSQHQRLH-TGEKPY 531
Query: 493 QCSLCPRKYPNLMALRNHVRVH-------CKAARRSADIGAEGAPSHLKVELPPDPVEAE 545
C+ C + + + L H R+H CK ++ G++ H ++ P E +
Sbjct: 532 VCNECGKAFARGLLLIQHQRIHTGEKPYQCKECGKAFIRGSQ-LTQHQRIHTGEKPYECK 590
Query: 546 ----AAPHTDQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGE 601
A H Q + H+ T P + C C F + L RH H GE
Sbjct: 591 ECGKAFSHGSQ--LTLHQRIHTGEKP-------YECRECRKAFTQSSHLSRHQRIH-TGE 640
Query: 602 KENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTH 639
K + C++CGK++ L H++ H
Sbjct: 641 KP-------------YQCKECGKAFTRGSQLTQHQRIH 665
Score = 122 bits (307), Expect = 2e-27
Identities = 87/309 (28%), Positives = 122/309 (39%), Gaps = 58/309 (18%)
Query: 221 FTGGQEPTQSPPAE-EERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNL 278
F G + TQ E+ Y+C +CGK + H LT H++ HT Y C C K F+
Sbjct: 372 FIRGSQLTQHQRIHTNEKPYECKECGKMFSHGSQLTQHQRIHTGEKPYQCKECGKAFNRG 431
Query: 279 MALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNG--- 335
L H R+H +PY C C + F EL +H++ H GE+ +E G G
Sbjct: 432 SLLTRHQRIHTGEKPYECKECGKTFSRGSELTQHERIHTGEKPY-ECKECGKSFIRGSQL 490
Query: 336 ------HTDESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSL 389
HT E + S+ LS L +P+ C +CG+ + L
Sbjct: 491 TQHQRIHTGEKPYECKECRMAFTQSSHLSQHQRLHTGE----KPYVCNECGKAFARGLLL 546
Query: 390 INHRKSHQTGV--YPCSLCSKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAPLLLAE 447
I H++ H TG Y C C K + L H R H GE
Sbjct: 547 IQHQRIH-TGEKPYQCKECGKAFIRGSQLTQHQRIH------TGE--------------- 584
Query: 448 TTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLM 505
+PY+C ECG+A+ H L H+ H TGE Y+C C + +
Sbjct: 585 ---------------KPYECKECGKAFSHGSQLTLHQRIH-TGEKPYECRECRKAFTQSS 628
Query: 506 ALRNHVRVH 514
L H R+H
Sbjct: 629 HLSRHQRIH 637
Score = 116 bits (291), Expect = 2e-25
Identities = 114/485 (23%), Positives = 180/485 (37%), Gaps = 107/485 (22%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C++ F L +L H+ + + +PY C++CG+ + L H++
Sbjct: 281 CKECRKVFTQLSQLILHKRI------------HTGEKPYECKECGKAFICGSQLSQHQKI 328
Query: 70 HE-TGLFPCTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHLQGETVSTDSWG 128
H + C CG+ F L H R H E +P + +E
Sbjct: 329 HNGEKPYECKECGRAFIRGSLLMQHQRIHTGE-----KPYKCEECGKAF----------- 372
Query: 129 QRLGSSEGWENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGADGW 187
+ S+ ++Q HT E P +C+ + G+ R G + E G
Sbjct: 373 --IRGSQLTQHQRIHTNEKPYECKEC-GKMFSHGSQLTQHQRIHTGEKPYQCKECG---- 425
Query: 188 GPSTNSARAPPLPIPASSLLSNLEQY-LAESVVNFTGGQEPTQSPPAEE-ERRYKCSQCG 245
+ L + + + Y E F+ G E TQ E+ Y+C +CG
Sbjct: 426 ----KAFNRGSLLTRHQRIHTGEKPYECKECGKTFSRGSELTQHERIHTGEKPYECKECG 481
Query: 246 KTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFR 304
K++ LT H++ HT Y C C F+ L H RLH +PY C C + F
Sbjct: 482 KSFIRGSQLTQHQRIHTGEKPYECKECRMAFTQSSHLSQHQRLHTGEKPYVCNECGKAFA 541
Query: 305 LPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSGELE 364
L++HQ+ H GE+ + +E G G QL Q ++ +GE
Sbjct: 542 RGLLLIQHQRIHTGEKPY-QCKECGKAFIRG-------SQLTQHQRIH-------TGE-- 584
Query: 365 DSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFNAAALKNHVRA 422
+P+ C +CG+ + H L H++ H TG Y C C K ++ L H R
Sbjct: 585 -------KPYECKECGKAFSHGSQLTLHQRIH-TGEKPYECRECRKAFTQSSHLSRHQRI 636
Query: 423 HHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVN 482
H GE +PY+C ECG+A+ L
Sbjct: 637 H------TGE------------------------------KPYQCKECGKAFTRGSQLTQ 660
Query: 483 HRHSH 487
H+ H
Sbjct: 661 HQRIH 665
Score = 115 bits (288), Expect = 4e-25
Identities = 103/408 (25%), Positives = 154/408 (37%), Gaps = 100/408 (24%)
Query: 275 FSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTN 334
F+ L HSR H+ +PY C C + FR L +HQ H GE+ +E K
Sbjct: 120 FNQHTYLSQHSRCHSTEKPYKCKECGKAFRRASHLTQHQSIHTGEKP---YECKQCGKA- 175
Query: 335 GHTDESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRK 394
S QL Q L+ +GE +P+ C +CG+ + + LI H +
Sbjct: 176 ----FSRDSQLSLHQRLH-------TGE---------KPYACKECGKAFTQSSQLILHHR 215
Query: 395 SHQTG--VYPCSLCSKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAPLLLAETTHKE 452
H TG Y C C K ++ L H + H GE
Sbjct: 216 IH-TGEKPYKCEECGKAFIRSSQLTRHQKVH------TGE-------------------- 248
Query: 453 EEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNH 510
+PY+C ECG+A+ L H+ H TGE Y+C C + + L L H
Sbjct: 249 ----------KPYECKECGKAFTQNSQLTLHQRLH-TGEKLYECKECRKVFTQLSQLILH 297
Query: 511 VRVH-------CKAARRSADIGAEGAPSHLKVELPPDPVEAEAAPHT--DQDHVCKHEEE 561
R+H CK ++ G++ H K+ P E + + +H+
Sbjct: 298 KRIHTGEKPYECKECGKAFICGSQ-LSQHQKIHNGEKPYECKECGRAFIRGSLLMQHQRI 356
Query: 562 ATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRD 621
T P + C CG F L +H R T P + C++
Sbjct: 357 HTGEKP-------YKCEECGKAFIRGSQLTQH-----------QRIHTNEKP---YECKE 395
Query: 622 CGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHS 667
CGK + H L H++ H TG+ + C C K F+ + + H R H+
Sbjct: 396 CGKMFSHGSQLTQHQRIH-TGEKPYQCKECGKAFNRGSLLTRHQRIHT 442
Score = 98.2 bits (243), Expect = 6e-20
Identities = 91/343 (26%), Positives = 138/343 (40%), Gaps = 41/343 (11%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C + F +L++H+ + + +PY C++CG+ + H L H+R
Sbjct: 365 CEECGKAFIRGSQLTQHQRI------------HTNEKPYECKECGKMFSHGSQLTQHQRI 412
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPEGRRRHRP-----PRPKEATPHLQGETV 122
H TG P C CGK F+ L H R H E + R E T H + T
Sbjct: 413 H-TGEKPYQCKECGKAFNRGSLLTRHQRIHTGEKPYECKECGKTFSRGSELTQHERIHTG 471
Query: 123 STDSWGQRLGSS-----EGWENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQREGLAS 176
+ G S + ++Q HT E P +C+ R A L QR
Sbjct: 472 EKPYECKECGKSFIRGSQLTQHQRIHTGEKPYECKEC---RMAFTQSSHLSQHQR----L 524
Query: 177 HPGPEDGADGWGPSTNSARAPPLPIPASSLLSNLEQ--YLAESVVNFTGGQEPTQSPPAE 234
H G + A A L + + E+ E F G + TQ
Sbjct: 525 HTGEKPYVCN---ECGKAFARGLLLIQHQRIHTGEKPYQCKECGKAFIRGSQLTQHQRIH 581
Query: 235 E-ERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYR 292
E+ Y+C +CGK + H LT H++ HT Y C C K F+ L H R+H +
Sbjct: 582 TGEKPYECKECGKAFSHGSQLTLHQRIHTGEKPYECRECRKAFTQSSHLSRHQRIHTGEK 641
Query: 293 PYHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNG 335
PY C C + F +L +HQ+ H E+ ++E G+ ++G
Sbjct: 642 PYQCKECGKAFTRGSQLTQHQRIHISEKSF-EYKECGIDFSHG 683
Score = 53.9 bits (128), Expect = 1e-06
Identities = 27/68 (39%), Positives = 34/68 (50%), Gaps = 1/68 (1%)
Query: 1719 LKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQ 1778
L HSR H+ K + C CGKAFR A+ L H +H E P+ C C + F R
Sbjct: 126 LSQHSRCHSTEKPYKCKECGKAFRRASHLTQHQSIHT-GEKPYECKQCGKAFSRDSQLSL 184
Query: 1779 HQQQHQEE 1786
HQ+ H E
Sbjct: 185 HQRLHTGE 192
Score = 50.1 bits (118), Expect = 2e-05
Identities = 24/60 (40%), Positives = 31/60 (51%), Gaps = 3/60 (5%)
Query: 43 SIPRPYRCQQCGRGYRHPGSLVNHRRTHETGLFP--CTTCGKDFSNPMALKSHMRTHAPE 100
S +PY+C++CG+ +R L H+ H TG P C CGK FS L H R H E
Sbjct: 134 STEKPYKCKECGKAFRRASHLTQHQSIH-TGEKPYECKQCGKAFSRDSQLSLHQRLHTGE 192
Score = 48.5 bits (114), Expect = 6e-05
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 15/94 (15%)
Query: 9 SCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRR 68
+C +C + F +L H + + +PY+C++CG+ + L H++
Sbjct: 196 ACKECGKAFTQSSQLILHHRI------------HTGEKPYKCEECGKAFIRSSQLTRHQK 243
Query: 69 THETGLFP--CTTCGKDFSNPMALKSHMRTHAPE 100
H TG P C CGK F+ L H R H E
Sbjct: 244 VH-TGEKPYECKECGKAFTQNSQLTLHQRLHTGE 276
Score = 48.1 bits (113), Expect = 8e-05
Identities = 28/93 (30%), Positives = 39/93 (41%), Gaps = 15/93 (16%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C C + F +LS H+ L + +PY C++CG+ + L+ H R
Sbjct: 169 CKQCGKAFSRDSQLSLHQRL------------HTGEKPYACKECGKAFTQSSQLILHHRI 216
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPE 100
H TG P C CGK F L H + H E
Sbjct: 217 H-TGEKPYKCEECGKAFIRSSQLTRHQKVHTGE 248
>gi|154800445 zinc finger protein 62 homolog [Homo sapiens]
Length = 840
Score = 190 bits (483), Expect = 1e-47
Identities = 200/854 (23%), Positives = 346/854 (40%), Gaps = 146/854 (17%)
Query: 600 GEKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMA 657
G S + T + + C +CGKS++++ L+ H+ H TG+ + C C F + +
Sbjct: 64 GTSYPSLQQKTNAVKKLHKCDECGKSFKYNSRLVQHKIMH-TGEKRYECDDCGGTFRSSS 122
Query: 658 AMKNHLRRHSRRRSRRHRKRAGGASGGREAKLLAAESWTRELEDNEGLESPQDPSGESPH 717
+++ H R H+ + ++ G + + L+ + +S H
Sbjct: 123 SLRVHKRIHTGEKP--YKCEECGKAYMSYSSLI---------------------NHKSTH 159
Query: 718 GAEGNLESDGDCLQAESEGDKCGLERDETHFQGDK--ESGGTGEGLERKDASLLDNLDIP 775
E N + D +C +S L++ + G+K E G G+ +
Sbjct: 160 SGEKNCKCD-EC--GKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHKRIHT 216
Query: 776 GEEGGGTHFC----DSLTGVDEDQKPATGQ-PNSSSHSANAVTGWQAGAAHT-------- 822
GE+ C + +G+ ++ TG+ P A + H
Sbjct: 217 GEKPYECDICGKTFSNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSIHFGDKP 276
Query: 823 --CSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQ 879
C +C SF +++ L+ H+ H Y+C C K F + L H + H T +
Sbjct: 277 YKCDECEKSFNYSSLLIQHKVIHTGEKPYECDECGKAFRNSSGLIVHKRIH-----TGEK 331
Query: 880 PFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAE 939
P+ C +CG F +G +H+ H E E ++
Sbjct: 332 PYKCDVCGKAFSYSSGLAVHK-SIHPGKKAHECKE--------------------CGKSF 370
Query: 940 LLNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDA 999
N L + + + ++C CG+T+ + L+ H + + + P V G A
Sbjct: 371 SYNSLLLQHRTIHTGERPYVCDVCGKTFRNNAGLKVHRRLHTG-----EKPYKCDVCGKA 425
Query: 1000 MEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGE--SLLEAQPR------P 1051
+ S L++ GE P S C + S LE R P
Sbjct: 426 Y--ISRSSLKNHKGIHLGE-----------KPYKCSYCEKSFNYSSALEQHKRIHTREKP 472
Query: 1052 FRCNQCGKTYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEP 1109
F C++CGK +R+ L H++IH TG+ + C C + Y +L++ NH HP
Sbjct: 473 FGCDECGKAFRNNSGLKVHKRIH-TGERPYKCEECGKAYISLSSLINHKSVHP------- 524
Query: 1110 QVGPIPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEV-EKLQEELKVEPLEEVARVK 1168
G P E ++K H+ E+ P + +V EK + +
Sbjct: 525 --GEKPFKCDECEKAFITYRTLTNHKKVHLGEK-PYKCDVCEKSFNYTSLLSQHRRVHTR 581
Query: 1169 EEVWEETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSH--Q 1226
E+ +E + E++ R ++ K + + ERP+ C+VCG++Y SLINH+ +H +
Sbjct: 582 EKPYE--CDRCEKVF-RNNSSLKVHKRIHTGERPYECDVCGKAYISHSSLINHKSTHPGK 638
Query: 1227 TGHFGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHME---- 1282
T H C C K F + +L +H+R+H + F+C ECGK+F L+ H+R+H
Sbjct: 639 TPH-TCDECGKAFFSSRTLISHKRVHLGEKPFKCVECGKSFSYSSLLSQHKRIHTGEKPY 697
Query: 1283 ---------RRGGGGT--RKATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ-YSCPT 1330
R G T ++ ++P+ C +CG+ Y SL+NH+ H+ Q Y+C
Sbjct: 698 VCDRCGKAFRNSSGLTVHKRIHTGEKPYECDECGKAYISHSSLINHKSVHQGKQPYNC-E 756
Query: 1331 CPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHEETE 1390
C K+++ R L H+R+H+ + RC CG++F R +L +H R H E
Sbjct: 757 CGKSFNYRSVLDQHKRIHTGKK----------PYRCNECGKAFNIRSNLTKHKRTHTGEE 806
Query: 1391 REPANGQGGLDGTA 1404
G GT+
Sbjct: 807 SLNVIYVGSYSGTS 820
Score = 189 bits (479), Expect = 3e-47
Identities = 180/769 (23%), Positives = 309/769 (40%), Gaps = 114/769 (14%)
Query: 1053 RCNQCGKTYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQ 1110
+C++CGK++++ LV H+ +H TG+ + C C + + ++ R H R H G +P
Sbjct: 82 KCDECGKSFKYNSRLVQHKIMH-TGEKRYECDDCGGTFRSSSSLRVHKRIHT---GEKPY 137
Query: 1111 VGPIPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEK-------LQEELKVEPLEE 1163
E G + + + ++K H E+ E K L + ++ E+
Sbjct: 138 KC---EECGKAYMSYSSLI---NHKSTHSGEKNCKCDECGKSFNYSSVLDQHKRIHTGEK 191
Query: 1164 VARVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQ 1223
E G + R+ T EK P+ C++CG+++ ++ L H++
Sbjct: 192 PYECGECGKAFRNSSGLRVHKRIHTGEK----------PYECDICGKTFSNSSGLRVHKR 241
Query: 1224 SHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHM 1281
H TG + C C K F +L NH+ IH + ++C EC K+F L H+ +H
Sbjct: 242 IH-TGEKPYECDECGKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVIHT 300
Query: 1282 ERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRM 1339
++P+ C +CG+ +R++ L+ H+R H TG+ Y C C K +S
Sbjct: 301 G-------------EKPYECDECGKAFRNSSGLIVHKRIH-TGEKPYKCDVCGKAFSYSS 346
Query: 1340 ALKDHQRLH---------------SENRRRRAGRSRRTAVR---CALCGRSFPGRGSLE- 1380
L H+ +H S N R+ T R C +CG++F L+
Sbjct: 347 GLAVHKSIHPGKKAHECKECGKSFSYNSLLLQHRTIHTGERPYVCDVCGKTFRNNAGLKV 406
Query: 1381 -RHLREHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRPGER 1439
R L E+ + G+ + S ++L +G+ HL + +
Sbjct: 407 HRRLHTGEKPYKCDVCGKAYI-----SRSSLKNHKGI-----------HLGEKPYKCSYC 450
Query: 1440 SQSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSPCH 1499
+S +++ E + + G G N+SG V + + E P
Sbjct: 451 EKSFNYSSALEQHKRIHTREKPFGCDECGKAFRNNSGLKVHKRIHTGERPYK-------- 502
Query: 1500 AGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHS-SCSQCGKTYCQSGSLLNHN-TNKTDRH 1557
C+ G + S N + + PG C +C K + +L NH + ++
Sbjct: 503 ---CEECGKAYISLSSLINHKS---VHPGEKPFKCDECEKAFITYRTLTNHKKVHLGEKP 556
Query: 1558 Y-CLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQVPA 1616
Y C +C K F H H + + C C K F ++ L H + H + P
Sbjct: 557 YKCDVCEKSFNYTSLLSQHRRVHTREKPYECDRCEKVFRNNSSLKVHKRIHT---GERPY 613
Query: 1617 QMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVERARGGQAVTS-MAAEDKER 1675
+ + KA ++ P +TP E + + + S E+
Sbjct: 614 ECDVCG--KAYISHSSLI----NHKSTHPGKTPHTCDECGKAFFSSRTLISHKRVHLGEK 667
Query: 1676 PFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCC 1734
PF+C +CG+S+ ++ L H++ HT Y C C K N L H R HT K + C
Sbjct: 668 PFKCVECGKSFSYSSLLSQHKRIHTGEKPYVCDRCGKAFRNSSGLTVHKRIHTGEKPYEC 727
Query: 1735 SICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQH 1783
CGKA+ + + L H VH ++ P+ C C + F R QH++ H
Sbjct: 728 DECGKAYISHSSLINHKSVHQGKQ-PYNC-ECGKSFNYRSVLDQHKRIH 774
Score = 178 bits (451), Expect = 5e-44
Identities = 173/699 (24%), Positives = 259/699 (37%), Gaps = 130/699 (18%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C DC F S L H+ + + +PY+C++CG+ Y SL+NH+ T
Sbjct: 111 CDDCGGTFRSSSSLRVHKRI------------HTGEKPYKCEECGKAYMSYSSLINHKST 158
Query: 70 HE-TGLFPCTTCGKDFSNPMALKSHMRTHAPE--------GRR-RHRPPRPKEATPHLQG 119
H C CGK F+ L H R H E G+ R+ H
Sbjct: 159 HSGEKNCKCDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHKRIHTGE 218
Query: 120 ETVSTDSWGQRLGSSEGWE-NQTKHTEETP-DCESVPDPRAASGTWEDLPTRQREGLASH 177
+ D G+ +S G ++ HT E P +C+ T L +H
Sbjct: 219 KPYECDICGKTFSNSSGLRVHKRIHTGEKPYECDECGKAFITCRT-----------LLNH 267
Query: 178 PGPEDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEER 237
G P N L + V TG E+
Sbjct: 268 KSIHFG------------DKPYKCDECEKSFNYSSLLIQHKVIHTG------------EK 303
Query: 238 RYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHC 296
Y+C +CGK ++++ L H++ HT Y C +C K FS L H +H + + C
Sbjct: 304 PYECDECGKAFRNSSGLIVHKRIHTGEKPYKCDVCGKAFSYSSGLAVHKSIHPGKKAHEC 363
Query: 297 PHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAE 356
C + F LL+H+ H GER + G T ++ ++ G
Sbjct: 364 KECGKSFSYNSLLLQHRTIHTGERPY-------VCDVCGKTFRNNAGLKVHRRLHTGE-- 414
Query: 357 LSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSH-QTGVYPCSLCSKQLFNAAA 415
+P++C CG+ Y SL NH+ H Y CS C K ++A
Sbjct: 415 ---------------KPYKCDVCGKAYISRSSLKNHKGIHLGEKPYKCSYCEKSFNYSSA 459
Query: 416 LKNHVRAHHRPRQ-GVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAY 474
L+ H R H R + G E G+ + L + + H E RPYKC ECG+AY
Sbjct: 460 LEQHKRIHTREKPFGCDECGKAFRNNSGLKVHKRIHTGE---------RPYKCEECGKAY 510
Query: 475 RHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHCKAARRSADIGAEG---- 528
SL+NH+ H GE ++C C + + L NH +VH D+ +
Sbjct: 511 ISLSSLINHKSVH-PGEKPFKCDECEKAFITYRTLTNHKKVHLGEKPYKCDVCEKSFNYT 569
Query: 529 --APSHLKVELPPDPVEAEAAPHT--DQDHVCKHEEEATDITPAADKTAAHICSICGLLF 584
H +V P E + + + H+ T P + C +CG +
Sbjct: 570 SLLSQHRRVHTREKPYECDRCEKVFRNNSSLKVHKRIHTGERP-------YECDVCGKAY 622
Query: 585 EDAESLERHGLTHGAGE--------KENSRTETTMSPPRA------FACRDCGKSYRHSG 630
SL H TH K + T +S R F C +CGKS+ +S
Sbjct: 623 ISHSSLINHKSTHPGKTPHTCDECGKAFFSSRTLISHKRVHLGEKPFKCVECGKSFSYSS 682
Query: 631 SLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHS 667
L H++ H TG+ + C C K F + + H R H+
Sbjct: 683 LLSQHKRIH-TGEKPYVCDRCGKAFRNSSGLTVHKRIHT 720
Score = 157 bits (396), Expect = 1e-37
Identities = 158/647 (24%), Positives = 244/647 (37%), Gaps = 131/647 (20%)
Query: 46 RPYRCQQCGRGYRHPGSLVNHRRTHETGL-FPCTTCGKDFSNPMALKSHMRTHAPEGRRR 104
+PY C +CG+ + +L+NH+ H + C C K F+ L H H E
Sbjct: 247 KPYECDECGKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVIHTGE---- 302
Query: 105 HRPPRPKEATPHLQGETVSTDSWGQRLGSSEGW-ENQTKHTEETP-DCESVPDPRAASGT 162
+P E D G+ +S G ++ HT E P C+ + S
Sbjct: 303 ----KPYEC-----------DECGKAFRNSSGLIVHKRIHTGEKPYKCDVCGKAFSYSS- 346
Query: 163 WEDLPTRQREGLASHPGPEDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFT 222
GLA H G + + +SLL L ++ T
Sbjct: 347 ----------GLAVHKSIHPGK-----KAHECKECGKSFSYNSLL------LQHRTIH-T 384
Query: 223 GGQEPTQSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMAL 281
G ER Y C CGKT+++ L HR+ HT Y C +C K + + +L
Sbjct: 385 G------------ERPYVCDVCGKTFRNNAGLKVHRRLHTGEKPYKCDVCGKAYISRSSL 432
Query: 282 KNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESS 341
KNH +H +PY C +C + F L +H++ H E+
Sbjct: 433 KNHKGIHLGEKPYKCSYCEKSFNYSSALEQHKRIHTREKP------------------FG 474
Query: 342 QDQLPSAQMLNGSAELST---SGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQ- 397
D+ A N ++ +GE RP++C +CG+ Y SLINH+ H
Sbjct: 475 CDECGKAFRNNSGLKVHKRIHTGE---------RPYKCEECGKAYISLSSLINHKSVHPG 525
Query: 398 TGVYPCSLCSKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPT 457
+ C C K L NH + H + + + S LL E
Sbjct: 526 EKPFKCDECEKAFITYRTLTNHKKVHLGEKPYKCDVCEKSFNYTSLLSQHRRVHTRE--- 582
Query: 458 TTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHC 515
+PY+C C + +R+ SL H+ H TGE Y+C +C + Y + +L NH H
Sbjct: 583 -----KPYECDRCEKVFRNNSSLKVHKRIH-TGERPYECDVCGKAYISHSSLINHKSTHP 636
Query: 516 KAARRSAD------IGAEGAPSHLKVELPPDPVEAEAA--PHTDQDHVCKHEEEATDITP 567
+ D + SH +V L P + + + +H+ T P
Sbjct: 637 GKTPHTCDECGKAFFSSRTLISHKRVHLGEKPFKCVECGKSFSYSSLLSQHKRIHTGEKP 696
Query: 568 AADKTAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYR 627
++C CG F ++ L H H GEK + C +CGK+Y
Sbjct: 697 -------YVCDRCGKAFRNSSGLTVHKRIH-TGEKP-------------YECDECGKAYI 735
Query: 628 HSGSLINHRQTHQ-TGDFSCGACAKHFHTMAAMKNHLRRHSRRRSRR 673
SLINH+ HQ ++C C K F+ + + H R H+ ++ R
Sbjct: 736 SHSSLINHKSVHQGKQPYNC-ECGKSFNYRSVLDQHKRIHTGKKPYR 781
Score = 155 bits (391), Expect = 4e-37
Identities = 194/840 (23%), Positives = 314/840 (37%), Gaps = 109/840 (12%)
Query: 508 RNHVRVHCKAARRSADIGAE--GAPSHLKVELPPDPVEAEAAPHTDQDHVCKHEEE---A 562
++ +R A+ +A+I E G S + L P + + P + E
Sbjct: 5 KSSIREAISKAKSTANIKTEQEGEASEKSLHLSPQHITHQTMPIGQRGSEQGKRVENING 64
Query: 563 TDITPAADKTAA----HICSICGLLFEDAESLERHGLTHGAGEKENS--------RTETT 610
T KT A H C CG F+ L +H + H GEK R+ ++
Sbjct: 65 TSYPSLQQKTNAVKKLHKCDECGKSFKYNSRLVQHKIMH-TGEKRYECDDCGGTFRSSSS 123
Query: 611 M-------SPPRAFACRDCGKSYRHSGSLINHRQTHQ-TGDFSCGACAKHFHTMAAMKNH 662
+ + + + C +CGK+Y SLINH+ TH + C C K F+ + + H
Sbjct: 124 LRVHKRIHTGEKPYKCEECGKAYMSYSSLINHKSTHSGEKNCKCDECGKSFNYSSVLDQH 183
Query: 663 LRRHSRRR---SRRHRKRAGGASGGREAKLLAAESWTRELEDNEGLESPQDPSGESPHGA 719
R H+ + K +SG R K + + + E + ++ + SG H
Sbjct: 184 KRIHTGEKPYECGECGKAFRNSSGLRVHKRI--HTGEKPYECDICGKTFSNSSGLRVHKR 241
Query: 720 EGNLESDGDCLQAESEGDKCG---------LERDETHFQGDKESGGTGEGLERKDASLLD 770
E +C D+CG L HF GDK +SLL
Sbjct: 242 IHTGEKPYEC-------DECGKAFITCRTLLNHKSIHF-GDKPYKCDECEKSFNYSSLLI 293
Query: 771 NLDIPGEEGGGTHFCD-------SLTGVDEDQKPATGQPNSSSHSANAVTGWQAGAA--- 820
+ G + CD + +G+ ++ TG+ + +G A
Sbjct: 294 QHKVI-HTGEKPYECDECGKAFRNSSGLIVHKRIHTGEKPYKCDVCGKAFSYSSGLAVHK 352
Query: 821 --------HTCSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHR 871
H C +CG SF + + LL HR H Y C +C K F + L+ H + H
Sbjct: 353 SIHPGKKAHECKECGKSFSYNSLLLQHRTIHTGERPYVCDVCGKTFRNNAGLKVHRRLH- 411
Query: 872 PGEATSAQPFLCCLCGMIFPGRAGYR----LHRRQAHSSSGMTEGSEEEGEEEGVAEAAP 927
T +P+ C +CG + R+ + +H + E S +
Sbjct: 412 ----TGEKPYKCDVCGKAYISRSSLKNHKGIHLGEKPYKCSYCEKSFNYSSALEQHKRIH 467
Query: 928 ARSPPL---QLSEAELLNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGT 984
R P + +A N + + + + + C CG+ Y L SL +H+S G
Sbjct: 468 TREKPFGCDECGKAFRNNSGLKVHKRIHTGERPYKCEECGKAYISLSSL-INHKSVHPGE 526
Query: 985 TADKAPSPLGVAGDAMEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESL 1044
K D E + N G+ + + +
Sbjct: 527 KPFKC--------DECEKAF-ITYRTLTNHKKVHLGEKPYKCDVCEKSFNYTSLLSQHRR 577
Query: 1045 LEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHP 1102
+ + +P+ C++C K +R+ SL H++IH TG+ + C VC + Y + ++ NH HP
Sbjct: 578 VHTREKPYECDRCEKVFRNNSSLKVHKRIH-TGERPYECDVCGKAYISHSSLINHKSTHP 636
Query: 1103 RCKGSEPQV-GPIPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPL 1161
G P +A SS + KP E G + L + ++
Sbjct: 637 ---GKTPHTCDECGKAFFSSRTLISHKRVHLGEKPFKCVECGKSFSYSSLLSQHKRIHTG 693
Query: 1162 EEVARVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINH 1221
E+ G + R+ T EK P+ C+ CG++Y SLINH
Sbjct: 694 EKPYVCDRCGKAFRNSSGLTVHKRIHTGEK----------PYECDECGKAYISHSSLINH 743
Query: 1222 RQSHQTGH-FGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVH 1280
+ HQ + C+ C K F+ L H+RIH + +RC+ECGKAF +R L H+R H
Sbjct: 744 KSVHQGKQPYNCE-CGKSFNYRSVLDQHKRIHTGKKPYRCNECGKAFNIRSNLTKHKRTH 802
Score = 154 bits (389), Expect = 8e-37
Identities = 120/470 (25%), Positives = 195/470 (41%), Gaps = 74/470 (15%)
Query: 218 VVNFTGGQEPT-QSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEF 275
V N G P+ Q ++ +KC +CGK++K+ L H+ HT Y C C F
Sbjct: 59 VENINGTSYPSLQQKTNAVKKLHKCDECGKSFKYNSRLVQHKIMHTGEKRYECDDCGGTF 118
Query: 276 SNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNG 335
+ +L+ H R+H +PY C C + + L+ H+ +H GE+ N
Sbjct: 119 RSSSSLRVHKRIHTGEKPYKCEECGKAYMSYSSLINHKSTHSGEK-------------NC 165
Query: 336 HTDESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKS 395
DE + N S+ L + +P+ CG+CG+ +R++ L H++
Sbjct: 166 KCDECGKS-------FNYSSVLDQHKRIHTG----EKPYECGECGKAFRNSSGLRVHKRI 214
Query: 396 HQTG--VYPCSLCSKQLFNAAALKNHVRAH--HRPRQGVGENGQPSVPPAPLLLAETTHK 451
H TG Y C +C K N++ L+ H R H +P + E G+ + LL ++ H
Sbjct: 215 H-TGEKPYECDICGKTFSNSSGLRVHKRIHTGEKPYE-CDECGKAFITCRTLLNHKSIH- 271
Query: 452 EEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRN 509
+PYKC EC +++ + L+ H+ H TGE Y+C C + + N L
Sbjct: 272 --------FGDKPYKCDECEKSFNYSSLLIQHKVIH-TGEKPYECDECGKAFRNSSGLIV 322
Query: 510 HVRVHCKAARRSADI------GAEGAPSHLKVELPPDPVEAE--AAPHTDQDHVCKHEEE 561
H R+H D+ + G H + E + + + +H
Sbjct: 323 HKRIHTGEKPYKCDVCGKAFSYSSGLAVHKSIHPGKKAHECKECGKSFSYNSLLLQHRTI 382
Query: 562 ATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRD 621
T P ++C +CG F + L+ H H GEK + C
Sbjct: 383 HTGERP-------YVCDVCGKTFRNNAGLKVHRRLH-TGEK-------------PYKCDV 421
Query: 622 CGKSYRHSGSLINHRQTH-QTGDFSCGACAKHFHTMAAMKNHLRRHSRRR 670
CGK+Y SL NH+ H + C C K F+ +A++ H R H+R +
Sbjct: 422 CGKAYISRSSLKNHKGIHLGEKPYKCSYCEKSFNYSSALEQHKRIHTREK 471
Score = 128 bits (321), Expect = 6e-29
Identities = 113/442 (25%), Positives = 178/442 (40%), Gaps = 80/442 (18%)
Query: 236 ERRYKCSQCGKTYKHAGSLTNHRQSHTLGI--YPCAICFKEFSNLMALKNHSRLHAQYRP 293
E+ YKC CGK Y SL NH+ H LG Y C+ C K F+ AL+ H R+H + +P
Sbjct: 414 EKPYKCDVCGKAYISRSSLKNHKGIH-LGEKPYKCSYCEKSFNYSSALEQHKRIHTREKP 472
Query: 294 YHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMP------TTNGHTDESSQDQLPS 347
+ C C + FR L H++ H GER + EE G N + +
Sbjct: 473 FGCDECGKAFRNNSGLKVHKRIHTGERPY-KCEECGKAYISLSSLINHKSVHPGEKPFKC 531
Query: 348 AQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSH-QTGVYPCSLC 406
+ T + L E +P++C C +++ + L HR+ H + Y C C
Sbjct: 532 DECEKAFITYRTLTNHKKVHLGE-KPYKCDVCEKSFNYTSLLSQHRRVHTREKPYECDRC 590
Query: 407 SKQLFNAAALKNHVRAH--HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPT------- 457
K N ++LK H R H RP + G+ + + L+ ++TH + T
Sbjct: 591 EKVFRNNSSLKVHKRIHTGERPYE-CDVCGKAYISHSSLINHKSTHPGKTPHTCDECGKA 649
Query: 458 -----TTLDHR-------PYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPN 503
T + H+ P+KC ECG+++ + L H+ H TGE Y C C + + N
Sbjct: 650 FFSSRTLISHKRVHLGEKPFKCVECGKSFSYSSLLSQHKRIH-TGEKPYVCDRCGKAFRN 708
Query: 504 LMALRNHVRVHCKAARRSADIGAEGAPSHLKVELPPDPVEAEAAPHTDQDHVCKHEEEAT 563
L H R+H D + SH + + ++ Q + C+
Sbjct: 709 SSGLTVHKRIHTGEKPYECDECGKAYISHSSL------INHKSVHQGKQPYNCE------ 756
Query: 564 DITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCG 623
CG F L++H H G+K + C +CG
Sbjct: 757 ----------------CGKSFNYRSVLDQHKRIH-TGKKP-------------YRCNECG 786
Query: 624 KSYRHSGSLINHRQTHQTGDFS 645
K++ +L H++TH TG+ S
Sbjct: 787 KAFNIRSNLTKHKRTH-TGEES 807
Score = 107 bits (267), Expect = 1e-22
Identities = 66/261 (25%), Positives = 121/261 (46%), Gaps = 33/261 (12%)
Query: 1146 QAEVEKLQEELKVEPLEEVARVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSERPF-S 1204
+ E E ++ L + P + + + + + +G+ +E T+ Q + ++ +
Sbjct: 24 EQEGEASEKSLHLSP-QHITHQTMPIGQRGSEQGKRVENINGTSYPSLQQKTNAVKKLHK 82
Query: 1205 CEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPRRFRCSE 1262
C+ CG+S+K+ L+ H+ H TG + C C F + SL+ H+RIH + ++C E
Sbjct: 83 CDECGKSFKYNSRLVQHKIMH-TGEKRYECDDCGGTFRSSSSLRVHKRIHTGEKPYKCEE 141
Query: 1263 CGKAFRLRKQLASHQRVHMERRGG---------------GGTRKATREDRPFRCGQCGRT 1307
CGKA+ L +H+ H + ++ ++P+ CG+CG+
Sbjct: 142 CGKAYMSYSSLINHKSTHSGEKNCKCDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKA 201
Query: 1308 YRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVR 1365
+R++ L H+R H TG+ Y C C KT+SN L+ H+R+H+ +
Sbjct: 202 FRNSSGLRVHKRIH-TGEKPYECDICGKTFSNSSGLRVHKRIHTGEK----------PYE 250
Query: 1366 CALCGRSFPGRGSLERHLREH 1386
C CG++F +L H H
Sbjct: 251 CDECGKAFITCRTLLNHKSIH 271
Score = 106 bits (265), Expect = 2e-22
Identities = 73/277 (26%), Positives = 117/277 (42%), Gaps = 24/277 (8%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C +CGK + S L H T + C +C K F N + H H + + C +C
Sbjct: 195 CGECGKAFRNSSGLRVHKRIHTGEKPYECDICGKTFSNSSGLRVHKRIHTGEKPYECDEC 254
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQ--------GKAQ 1642
GKAF + + L +H H + E++ + + + +V+ G+ GKA
Sbjct: 255 GKAFITCRTLLNHKSIHFGDKPYKCDECEKSFNYSSLLIQHKVIHTGEKPYECDECGKAF 314
Query: 1643 EAPS--------ETPRGPGESVERARGGQAVTSMAAEDKERPFR----CTQCGRSYRHAG 1690
S T P + + + +A P + C +CG+S+ +
Sbjct: 315 RNSSGLIVHKRIHTGEKPYKCDVCGKAFSYSSGLAVHKSIHPGKKAHECKECGKSFSYNS 374
Query: 1691 SLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEG 1749
LL H+ HT Y C +C K N LK H R HT K + C +CGKA+ + + L+
Sbjct: 375 LLLQHRTIHTGERPYVCDVCGKTFRNNAGLKVHRRLHTGEKPYKCDVCGKAYISRSSLKN 434
Query: 1750 HGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
H +H E P+ C +C + F + QH++ H E
Sbjct: 435 HKGIHL-GEKPYKCSYCEKSFNYSSALEQHKRIHTRE 470
Score = 104 bits (259), Expect = 9e-22
Identities = 79/278 (28%), Positives = 114/278 (41%), Gaps = 26/278 (9%)
Query: 1533 CSQCGKTYCQSGSLLNHN-TNKTDRHY-CLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C CGK Y SL NH + ++ Y C C K F A + H H + F C +C
Sbjct: 419 CDVCGKAYISRSSLKNHKGIHLGEKPYKCSYCEKSFNYSSALEQHKRIHTREKPFGCDEC 478
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQG--KAQEAPS-- 1646
GKAF ++ L H + H + +A + + V PG+ K E
Sbjct: 479 GKAFRNNSGLKVHKRIHTGERPYKCEECGKAYISLSSLINHKSVHPGEKPFKCDECEKAF 538
Query: 1647 ---------------ETPRGPGESVERARGGQAVTSM--AAEDKERPFRCTQCGRSYRHA 1689
E P + E++ ++ S +E+P+ C +C + +R+
Sbjct: 539 ITYRTLTNHKKVHLGEKPY-KCDVCEKSFNYTSLLSQHRRVHTREKPYECDRCEKVFRNN 597
Query: 1690 GSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLE 1748
SL H++ HT Y C +C K + SL NH TH H C CGKAF ++ L
Sbjct: 598 SSLKVHKRIHTGERPYECDVCGKAYISHSSLINHKSTHPGKTPHTCDECGKAFFSSRTLI 657
Query: 1749 GHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
H RVH E PF C C + F QH++ H E
Sbjct: 658 SHKRVHL-GEKPFKCVECGKSFSYSSLLSQHKRIHTGE 694
Score = 102 bits (255), Expect = 3e-21
Identities = 112/487 (22%), Positives = 176/487 (36%), Gaps = 67/487 (13%)
Query: 1326 YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLRE 1385
+ C C K++ L H+ +H+ +R C CG +F SL H R
Sbjct: 81 HKCDECGKSFKYNSRLVQHKIMHTGEKR----------YECDDCGGTFRSSSSLRVHKRI 130
Query: 1386 HEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRPGERSQSPIR 1445
H + G + +S N + E + E +S
Sbjct: 131 HTGEKPYKCEECGKAYMSYSSLINHKSTHSGEKNC--------------KCDECGKSFNY 176
Query: 1446 AASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSPCHAGDCQL 1505
++ + + + G G N SG V + + E+P + C +
Sbjct: 177 SSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHKRIHTGEKPYE-----------CDI 225
Query: 1506 NGPTLSHMDSWDNRDNSSQLQPGSHS-SCSQCGKTYCQSGSLLNHNT-NKTDRHY-CLLC 1562
G T S+ ++ G C +CGK + +LLNH + + D+ Y C C
Sbjct: 226 CGKTFSNSSGLRVH---KRIHTGEKPYECDECGKAFITCRTLLNHKSIHFGDKPYKCDEC 282
Query: 1563 SKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQVPAQMEEAR 1622
K F H H + + C +CGKAF + L H + H +A
Sbjct: 283 EKSFNYSSLLIQHKVIHTGEKPYECDECGKAFRNSSGLIVHKRIHTGEKPYKCDVCGKAF 342
Query: 1623 DPKAGTGEDQVVLPGQ--------GKA--------QEAPSETPRGP------GESVERAR 1660
+G + + PG+ GK+ Q T P G++
Sbjct: 343 SYSSGLAVHKSIHPGKKAHECKECGKSFSYNSLLLQHRTIHTGERPYVCDVCGKTFRNNA 402
Query: 1661 GGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSL 1719
G + + E+P++C CG++Y SL NH+ H Y CS C K +L
Sbjct: 403 GLKVHRRL--HTGEKPYKCDVCGKAYISRSSLKNHKGIHLGEKPYKCSYCEKSFNYSSAL 460
Query: 1720 KNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQH 1779
+ H R HT K C CGKAFR + L+ H R+H E P+ C C + + S + H
Sbjct: 461 EQHKRIHTREKPFGCDECGKAFRNNSGLKVHKRIHT-GERPYKCEECGKAYISLSSLINH 519
Query: 1780 QQQHQEE 1786
+ H E
Sbjct: 520 KSVHPGE 526
Score = 100 bits (248), Expect = 2e-20
Identities = 64/255 (25%), Positives = 110/255 (43%), Gaps = 12/255 (4%)
Query: 1533 CSQCGKTYCQSGSLLNHNT-NKTDRHY-CLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C +CGK Y SL+NH + + ++ + C C K F+ +H H+ + + C C
Sbjct: 503 CEECGKAYISLSSLINHKSVHPGEKPFKCDECEKAFITYRTLTNHKKVHLGEKPYKCDVC 562
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPR 1650
K+F L+ H + H R + P + + R K + + + E P E
Sbjct: 563 EKSFNYTSLLSQHRRVHTR---EKPYECD--RCEKVFRNNSSLKVHKRIHTGERPYECDV 617
Query: 1651 GPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLC 1709
+ + + + + P C +CG+++ + +L++H++ H + C C
Sbjct: 618 CGKAYISHS---SLINHKSTHPGKTPHTCDECGKAFFSSRTLISHKRVHLGEKPFKCVEC 674
Query: 1710 PKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRH 1769
K L H R HT K + C CGKAFR ++ L H R+H E P+ C C +
Sbjct: 675 GKSFSYSSLLSQHKRIHTGEKPYVCDRCGKAFRNSSGLTVHKRIHT-GEKPYECDECGKA 733
Query: 1770 FRRRISFVQHQQQHQ 1784
+ S + H+ HQ
Sbjct: 734 YISHSSLINHKSVHQ 748
Score = 98.6 bits (244), Expect = 5e-20
Identities = 71/257 (27%), Positives = 111/257 (43%), Gaps = 12/257 (4%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKT-DRHY-CLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C +CGK + + L H T +R Y C C K +++ + +H H + F C +C
Sbjct: 475 CDECGKAFRNNSGLKVHKRIHTGERPYKCEECGKAYISLSSLINHKSVHPGEKPFKCDEC 534
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPR 1650
KAF +++ L +H + H E++ + + + + V +E P E R
Sbjct: 535 EKAFITYRTLTNHKKVHLGEKPYKCDVCEKSFNYTSLLSQHRRV-----HTREKPYECDR 589
Query: 1651 GPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLC 1709
E V R V ERP+ C CG++Y SL+NH+ H + C C
Sbjct: 590 C--EKVFRNNSSLKVHKRI-HTGERPYECDVCGKAYISHSSLINHKSTHPGKTPHTCDEC 646
Query: 1710 PKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRH 1769
K + +L +H R H K C CGK+F ++ L H R+H E P+ C C +
Sbjct: 647 GKAFFSSRTLISHKRVHLGEKPFKCVECGKSFSYSSLLSQHKRIHTG-EKPYVCDRCGKA 705
Query: 1770 FRRRISFVQHQQQHQEE 1786
FR H++ H E
Sbjct: 706 FRNSSGLTVHKRIHTGE 722
Score = 97.8 bits (242), Expect = 8e-20
Identities = 68/229 (29%), Positives = 90/229 (39%), Gaps = 40/229 (17%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C CGK Y SL+NH + + H C C K F + SH H+ + F C +C
Sbjct: 615 CDVCGKAYISHSSLINHKSTHPGKTPHTCDECGKAFFSSRTLISHKRVHLGEKPFKCVEC 674
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPR 1650
GK+F L+ H + H TGE V GKA S
Sbjct: 675 GKSFSYSSLLSQHKRIH--------------------TGEKPYVCDRCGKAFRNSS---- 710
Query: 1651 GPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLC 1709
G +V + E+P+ C +CG++Y SL+NH+ H Y C C
Sbjct: 711 --GLTVHKR----------IHTGEKPYECDECGKAYISHSSLINHKSVHQGKQPYNCE-C 757
Query: 1710 PKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPRE 1758
K L H R HT K + C+ CGKAF + L H R H E
Sbjct: 758 GKSFNYRSVLDQHKRIHTGKKPYRCNECGKAFNIRSNLTKHKRTHTGEE 806
Score = 89.4 bits (220), Expect = 3e-17
Identities = 63/239 (26%), Positives = 91/239 (38%), Gaps = 39/239 (16%)
Query: 1547 LNHNTNKTDR-HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQ 1605
L TN + H C C K F H H + + C DCG F S L H +
Sbjct: 70 LQQKTNAVKKLHKCDECGKSFKYNSRLVQHKIMHTGEKRYECDDCGGTFRSSSSLRVHKR 129
Query: 1606 AHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVERARGGQAV 1665
H + P + EE GKA + S +
Sbjct: 130 IHT---GEKPYKCEEC-----------------GKAYMSYSSL----------------I 153
Query: 1666 TSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSR 1724
+ E+ +C +CG+S+ ++ L H++ HT Y C C K N L+ H R
Sbjct: 154 NHKSTHSGEKNCKCDECGKSFNYSSVLDQHKRIHTGEKPYECGECGKAFRNSSGLRVHKR 213
Query: 1725 THTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQH 1783
HT K + C ICGK F ++ L H R+H E P+ C C + F + + H+ H
Sbjct: 214 IHTGEKPYECDICGKTFSNSSGLRVHKRIHT-GEKPYECDECGKAFITCRTLLNHKSIH 271
Score = 53.9 bits (128), Expect = 1e-06
Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 1/84 (1%)
Query: 1703 LYPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFT 1762
L+ C C K L H HT KR+ C CG FR+++ L H R+H E P+
Sbjct: 80 LHKCDECGKSFKYNSRLVQHKIMHTGEKRYECDDCGGTFRSSSSLRVHKRIHTG-EKPYK 138
Query: 1763 CPHCPRHFRRRISFVQHQQQHQEE 1786
C C + + S + H+ H E
Sbjct: 139 CEECGKAYMSYSSLINHKSTHSGE 162
Score = 47.4 bits (111), Expect = 1e-04
Identities = 29/94 (30%), Positives = 42/94 (44%), Gaps = 15/94 (15%)
Query: 9 SCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRR 68
+C +C + F S L H+ + H +P++C +CG+ + + L H+R
Sbjct: 642 TCDECGKAFFSSRTLISHKRV-HLGE-----------KPFKCVECGKSFSYSSLLSQHKR 689
Query: 69 THETGLFP--CTTCGKDFSNPMALKSHMRTHAPE 100
H TG P C CGK F N L H R H E
Sbjct: 690 IH-TGEKPYVCDRCGKAFRNSSGLTVHKRIHTGE 722
Score = 45.4 bits (106), Expect = 5e-04
Identities = 26/90 (28%), Positives = 42/90 (46%), Gaps = 15/90 (16%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C + F LS+H+ + + +PY C +CG+ +R+ L H+R
Sbjct: 671 CVECGKSFSYSSLLSQHKRI------------HTGEKPYVCDRCGKAFRNSSGLTVHKRI 718
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTH 97
H TG P C CGK + + +L +H H
Sbjct: 719 H-TGEKPYECDECGKAYISHSSLINHKSVH 747
Score = 44.3 bits (103), Expect = 0.001
Identities = 30/93 (32%), Positives = 42/93 (45%), Gaps = 16/93 (17%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C + + S L H+ S +Q + PY C+ CG+ + + L H+R
Sbjct: 727 CDECGKAYISHSSLINHK-----SVHQGKQ-------PYNCE-CGKSFNYRSVLDQHKRI 773
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPE 100
H TG P C CGK F+ L H RTH E
Sbjct: 774 H-TGKKPYRCNECGKAFNIRSNLTKHKRTHTGE 805
Score = 43.1 bits (100), Expect = 0.002
Identities = 18/64 (28%), Positives = 36/64 (56%), Gaps = 3/64 (4%)
Query: 39 EEADSIPRPYRCQQCGRGYRHPGSLVNHRRTHETG--LFPCTTCGKDFSNPMALKSHMRT 96
++ +++ + ++C +CG+ +++ LV H+ H TG + C CG F + +L+ H R
Sbjct: 72 QKTNAVKKLHKCDECGKSFKYNSRLVQHKIMH-TGEKRYECDDCGGTFRSSSSLRVHKRI 130
Query: 97 HAPE 100
H E
Sbjct: 131 HTGE 134
>gi|122937229 zinc finger protein 629 [Homo sapiens]
Length = 869
Score = 188 bits (478), Expect = 4e-47
Identities = 206/873 (23%), Positives = 325/873 (37%), Gaps = 167/873 (19%)
Query: 225 QEPTQSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSHTLGIYP--CAICFKEFSNLMALK 282
+E Q PA E+ Y C++CGK++ L H++ HT G P C+ C K F+ L
Sbjct: 136 RELVQGRPAGAEKPYICNECGKSFSQWSKLLRHQRIHT-GERPNTCSECGKSFTQSSHLV 194
Query: 283 NHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQ 342
H R H +PY CP C + F L++HQ++H GE+ E +
Sbjct: 195 QHQRTHTGEKPYKCPDCGKCFSWSSNLVQHQRTHTGEKPY-------------KCTECEK 241
Query: 343 DQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--V 400
S ++ + S +GE +P++CG+C R + + LI H+ +H TG
Sbjct: 242 AFTQSTNLI--KHQRSHTGE---------KPYKCGECRRAFYRSSDLIQHQATH-TGEKP 289
Query: 401 YPCSLCSKQLFNAAALKNHVRAH--HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTT 458
Y C C K+ L H + H +P + E G+ + + L + TH E
Sbjct: 290 YKCPECGKRFGQNHNLLKHQKIHAGEKPYR-CTECGKSFIQSSELTQHQRTHTGE----- 343
Query: 459 TLDHRPYKCSECGRAYRHRGSLVNHRHSH-RTGEYQCSLCPRKYPNLMALRNHVRVH--- 514
+PY+C ECG+++ H +L+ H+ +H R ++C +C + + L H R H
Sbjct: 344 ----KPYECLECGKSFGHSSTLIKHQRTHLREDPFKCPVCGKTFTLSATLLRHQRTHTGE 399
Query: 515 ----CKAARRSADIGAEGAPSHLKVELPPDPVEAE--AAPHTDQDHVCKHEEEATDITPA 568
C +S + + +H ++ P + +H+ T P
Sbjct: 400 RPYKCPECGKSFSV-SSNLINHQRIHRGERPYICADCGKSFIMSSTLIRHQRIHTGEKP- 457
Query: 569 ADKTAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRH 628
+ CS CG F + L +H TH GEK + C +CGKS+
Sbjct: 458 ------YKCSDCGKSFIRSSHLIQHRRTH-TGEK-------------PYKCPECGKSFSQ 497
Query: 629 SGSLINHRQTHQTGD-FSCGACAKHFHTMAAMKNHLRRHSRRRSRRHRKRAGGASGGREA 687
S +LI H +TH + F C C K F ++ H H R ++ R + G +
Sbjct: 498 SSNLITHVRTHMDENLFVCSDCGKAFLEAHELEQHRVIHERGKTPARRAQGDSLLGLGDP 557
Query: 688 KLLAAESWTRELEDNEGLESPQDPSGESPHGAEGNLESDGDCLQAESEGDKCGLERDETH 747
LL P G PH CL + G+
Sbjct: 558 SLLT------------------PPPGAKPH----------KCLVCGKGFNDEGIFMQHQR 589
Query: 748 FQGDKESGGTGEGLERKDASLLDNLDIPGEEGGGTHFCDSLTGVDEDQKPATGQPNSSSH 807
+ +GL A L P G +S G E + A GQP
Sbjct: 590 IHIGENPYKNADGLIAHAAPKPPQLRSPRLPFRG----NSYPGAAEGRAEAPGQPLKPPE 645
Query: 808 SANAVT---GWQAGAAHTCSDCGHSFPHATGLLSHRPCHPPGIYQCSLCPKEFDSLPALR 864
+ G + + CS CG SF + LL H+ H G + L P L
Sbjct: 646 GQEGFSQRRGLLSSKTYICSHCGESFLDRSVLLQHQLTH--GNEKPFLFPDYRIGLG--- 700
Query: 865 SHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAE 924
+ P S +PF C C F G + L ++ H+ ++
Sbjct: 701 ---EGAGPSPFLSGKPFKCPECKQSF-GLSSELLLHQKVHAGGKSSQ------------- 743
Query: 925 AAPARSPPLQLSEAELLNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGT 984
+SP L S + LL L+ + A + C C ++ D +L RH ++
Sbjct: 744 ----KSPELGKSSSVLLEHLRSPLGARP-----YRCSDCRASFLDRVALTRHQETH---- 790
Query: 985 TADKAPSPLGVAGDAMEMVVDSVLEDIVNSVSGEGGDAKSQEGAG---TPLGDSLCIQGG 1041
T +K P+P +A+ + D QEG G TP S +G
Sbjct: 791 TQEKPPNPEDPPPEAVTLSTD-------------------QEGEGETPTPTESSSHGEGQ 831
Query: 1042 ESLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIH 1074
+ +P+ C +CG + +L+ HR H
Sbjct: 832 NPKTLVEEKPYLCPECGAGFTEVAALLLHRSCH 864
Score = 172 bits (436), Expect = 3e-42
Identities = 180/775 (23%), Positives = 281/775 (36%), Gaps = 155/775 (20%)
Query: 1050 RPFRCNQCGKTYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGS 1107
+P++C CGK + +LV H++ H TG+ + C C + + H R+H G
Sbjct: 204 KPYKCPDCGKCFSWSSNLVQHQRTH-TGEKPYKCTECEKAFTQSTNLIKHQRSHT---GE 259
Query: 1108 EP-QVGPIPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVAR 1166
+P + G A S + KP E G + L + K+ E+ R
Sbjct: 260 KPYKCGECRRAFYRSSDLIQHQATHTGEKPYKCPECGKRFGQNHNLLKHQKIHAGEKPYR 319
Query: 1167 VKEEVWEETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSH- 1225
E ++ ++ E+ T + E+P+ C CG+S+ H+ +LI H+++H
Sbjct: 320 CTE--CGKSFIQSSELTQHQRTH--------TGEKPYECLECGKSFGHSSTLIKHQRTHL 369
Query: 1226 QTGHFGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERR- 1284
+ F C C K F+ +L H+R H R ++C ECGK+F + L +HQR+H R
Sbjct: 370 REDPFKCPVCGKTFTLSATLLRHQRTHTGERPYKCPECGKSFSVSSNLINHQRIHRGERP 429
Query: 1285 ------GGGGTRKAT--------REDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSC 1328
G +T ++P++C CG+++ + L+ HRR+H TG+ Y C
Sbjct: 430 YICADCGKSFIMSSTLIRHQRIHTGEKPYKCSDCGKSFIRSSHLIQHRRTH-TGEKPYKC 488
Query: 1329 PTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHEE 1388
P C K++S L H R H + C+ CG++F LE+H HE
Sbjct: 489 PECGKSFSQSSNLITHVRTHMD----------ENLFVCSDCGKAFLEAHELEQHRVIHER 538
Query: 1389 TEREPANGQG-GLDGTAASEANLTGSQGLETQLGGAEPVPHL-------EDGVPRPGER- 1439
+ QG L G G L T GA+P L ++G+ +R
Sbjct: 539 GKTPARRAQGDSLLG--------LGDPSLLTPPPGAKPHKCLVCGKGFNDEGIFMQHQRI 590
Query: 1440 --SQSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSP 1497
++P + A GL H+ PQ L P
Sbjct: 591 HIGENPYKNAD---------------------GLIAHAAPKPPQ-LRSPRLPFRGNSYPG 628
Query: 1498 CHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHSSCSQCGKTYCQSGSLLNHNTNKTDRH 1557
G + G L + + L CS CG+++ LL H +
Sbjct: 629 AAEGRAEAPGQPLKPPEGQEGFSQRRGLLSSKTYICSHCGESFLDRSVLLQHQLTHGN-- 686
Query: 1558 YCLLCSKEFLNP-----VATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHS 1612
K FL P + + + + F CP+C ++F EL H + HA G S
Sbjct: 687 -----EKPFLFPDYRIGLGEGAGPSPFLSGKPFKCPECKQSFGLSSELLLHQKVHAGGKS 741
Query: 1613 QVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVERARGGQAVTSMAAED 1672
+ P GK+ E R P +
Sbjct: 742 SQKS-------------------PELGKSSSVLLEHLRSPLGA----------------- 765
Query: 1673 KERPFRCTQCGRSYRHAGSLLNHQKAHTTGLYPCSLCPKLLPNLLSLKNHSRTHTDPKRH 1732
RP+RC+ C S+ +L HQ+ HT P P LS T
Sbjct: 766 --RPYRCSDCRASFLDRVALTRHQETHTQEKPPNPEDPPPEAVTLSTDQEGEGETP---- 819
Query: 1733 CCSICGKAFRTAARLEGHGRVHAPR----EGPFTCPHCPRHFRRRISFVQHQQQH 1783
T HG P+ E P+ CP C F + + H+ H
Sbjct: 820 ----------TPTESSSHGEGQNPKTLVEEKPYLCPECGAGFTEVAALLLHRSCH 864
Score = 164 bits (414), Expect = 1e-39
Identities = 212/894 (23%), Positives = 315/894 (35%), Gaps = 239/894 (26%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C++C + F +L RH+ + + RP C +CG+ + LV H+RT
Sbjct: 152 CNECGKSFSQWSKLLRHQRI------------HTGERPNTCSECGKSFTQSSHLVQHQRT 199
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHLQGETVSTDSW 127
H TG P C CGK FS L H RTH E +P + T + T ST+
Sbjct: 200 H-TGEKPYKCPDCGKCFSWSSNLVQHQRTHTGE--------KPYKCTECEKAFTQSTNLI 250
Query: 128 GQRLGSSEGWENQTKHTEETPDCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGADGW 187
++Q HT E P + R A DL Q A+H G +
Sbjct: 251 ----------KHQRSHTGEKP--YKCGECRRAFYRSSDLIQHQ----ATHTGEK------ 288
Query: 188 GPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGKT 247
P P L + G E+ Y+C++CGK+
Sbjct: 289 ----------PYKCPECGKRFGQNHNLLKHQKIHAG------------EKPYRCTECGKS 326
Query: 248 YKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLP 306
+ + LT H+++HT Y C C K F + L H R H + P+ CP C + F L
Sbjct: 327 FIQSSELTQHQRTHTGEKPYECLECGKSFGHSSTLIKHQRTHLREDPFKCPVCGKTFTLS 386
Query: 307 RELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSGELEDS 366
LL HQ++H GER E + S+ ++N + GE
Sbjct: 387 ATLLRHQRTHTGERPYK-------------CPECGKSFSVSSNLINH--QRIHRGE---- 427
Query: 367 GLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTGV--YPCSLCSKQLFNAAALKNHVRAH- 423
RP+ C DCG+++ + +LI H++ H TG Y CS C K ++ L H R H
Sbjct: 428 -----RPYICADCGKSFIMSSTLIRHQRIH-TGEKPYKCSDCGKSFIRSSHLIQHRRTHT 481
Query: 424 -HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVN 482
+P + E G+ + L+ TH +D + CS+CG+A+ L
Sbjct: 482 GEKPYK-CPECGKSFSQSSNLITHVRTH---------MDENLFVCSDCGKAFLEAHELEQ 531
Query: 483 HRHSHRTGE----------------------------YQCSLCPRKYPNLMALRNHVRVH 514
HR H G+ ++C +C + + + H R+H
Sbjct: 532 HRVIHERGKTPARRAQGDSLLGLGDPSLLTPPPGAKPHKCLVCGKGFNDEGIFMQHQRIH 591
Query: 515 C-KAARRSAD-IGAEGAPSHLKVELPPDPVEAEAAPHTDQDHVCKHEEEATDITPAADK- 571
+ ++AD + A AP ++ P P + P + E + P +
Sbjct: 592 IGENPYKNADGLIAHAAPKPPQLRSPRLPFRGNSYPGAAEGRA---EAPGQPLKPPEGQE 648
Query: 572 ----------TAAHICSICGLLFEDAESLERHGLTHG-----------AGEKENSRTETT 610
+ +ICS CG F D L +H LTHG G E +
Sbjct: 649 GFSQRRGLLSSKTYICSHCGESFLDRSVLLQHQLTHGNEKPFLFPDYRIGLGEGAGPSPF 708
Query: 611 MSPPRAFACRDCGKSYRHSGSLINHRQTHQTGDFSCGACAKHFHTMAAMKNHLRRHSRRR 670
+S + F C +C +S+ S L+ H++ H G S + + + + HLR R
Sbjct: 709 LSG-KPFKCPECKQSFGLSSELLLHQKVH-AGGKSSQKSPELGKSSSVLLEHLRSPLGAR 766
Query: 671 SRRHRKRAGGASGGREAKLLAAESWTRELEDNEGLESPQDPSGESPHGAEGNLESDGDCL 730
R A L + TR E + E P +P P L
Sbjct: 767 PYR--------CSDCRASFLDRVALTRHQETHTQ-EKPPNPEDPPPEAVT---------L 808
Query: 731 QAESEGDKCGLERDETHFQGDKESGGTGEGLERKDASLLDNLDIPGEEGGGTHFCDSLTG 790
+ EG E ES GEG K T
Sbjct: 809 STDQEG--------EGETPTPTESSSHGEGQNPK------------------------TL 836
Query: 791 VDEDQKPATGQPNSSSHSANAVTGWQAGAAHTCSDCGHSFPHATGLLSHRPCHP 844
V+E KP + C +CG F LL HR CHP
Sbjct: 837 VEE--KP-----------------------YLCPECGAGFTEVAALLLHRSCHP 865
Score = 157 bits (397), Expect = 9e-38
Identities = 191/771 (24%), Positives = 297/771 (38%), Gaps = 177/771 (22%)
Query: 46 RPYRCQQCGRGYRHPGSLVNHRRTHETGLFP--CTTCGKDFSNPMALKSHMRTHAPEGRR 103
+PY C +CG+ + L+ H+R H TG P C+ CGK F+ L H RTH E
Sbjct: 148 KPYICNECGKSFSQWSKLLRHQRIH-TGERPNTCSECGKSFTQSSHLVQHQRTHTGE--- 203
Query: 104 RHRPPRPKEATPHLQGETVSTDSWGQRLGSSEGWENQTKHTEETP----DCESVPDPRAA 159
P+ + SW SS ++Q HT E P +CE A
Sbjct: 204 ----------KPYKCPDCGKCFSW-----SSNLVQHQRTHTGEKPYKCTECEK------A 242
Query: 160 SGTWEDLPTRQREGLASHPGPEDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVV 219
+L QR SH G + G R A S+L Q+ A
Sbjct: 243 FTQSTNLIKHQR----SHTGEKPYKCG------ECRR------AFYRSSDLIQHQATHT- 285
Query: 220 NFTGGQEPTQSPPAEE-----------------ERRYKCSQCGKTYKHAGSLTNHRQSHT 262
G++P + P + E+ Y+C++CGK++ + LT H+++HT
Sbjct: 286 ----GEKPYKCPECGKRFGQNHNLLKHQKIHAGEKPYRCTECGKSFIQSSELTQHQRTHT 341
Query: 263 -LGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQ 321
Y C C K F + L H R H + P+ CP C + F L LL HQ++H GER
Sbjct: 342 GEKPYECLECGKSFGHSSTLIKHQRTHLREDPFKCPVCGKTFTLSATLLRHQRTHTGERP 401
Query: 322 EPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGR 381
E + S+ ++N + GE RP+ C DCG+
Sbjct: 402 Y-------------KCPECGKSFSVSSNLIN--HQRIHRGE---------RPYICADCGK 437
Query: 382 TYRHAGSLINHRKSHQTG--VYPCSLCSKQLFNAAALKNHVRAH--HRPRQGVGENGQPS 437
++ + +LI H++ H TG Y CS C K ++ L H R H +P + E G+
Sbjct: 438 SFIMSSTLIRHQRIH-TGEKPYKCSDCGKSFIRSSHLIQHRRTHTGEKPYK-CPECGKSF 495
Query: 438 VPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE------ 491
+ L+ TH +D + CS+CG+A+ L HR H G+
Sbjct: 496 SQSSNLITHVRTH---------MDENLFVCSDCGKAFLEAHELEQHRVIHERGKTPARRA 546
Query: 492 ----------------------YQCSLCPRKYPNLMALRNHVRVHC-KAARRSAD-IGAE 527
++C +C + + + H R+H + ++AD + A
Sbjct: 547 QGDSLLGLGDPSLLTPPPGAKPHKCLVCGKGFNDEGIFMQHQRIHIGENPYKNADGLIAH 606
Query: 528 GAPSHLKVELPPDPVEAEAAPHTDQDHVCKHEEEATDITPAADK-----------TAAHI 576
AP ++ P P + P + + E + P + + +I
Sbjct: 607 AAPKPPQLRSPRLPFRGNSYPGAAEG---RAEAPGQPLKPPEGQEGFSQRRGLLSSKTYI 663
Query: 577 CSICGLLFEDAESLERHGLTHG-----------AGEKENSRTETTMSPPRAFACRDCGKS 625
CS CG F D L +H LTHG G E + +S + F C +C +S
Sbjct: 664 CSHCGESFLDRSVLLQHQLTHGNEKPFLFPDYRIGLGEGAGPSPFLS-GKPFKCPECKQS 722
Query: 626 YRHSGSLINHRQTHQTGDFSCGACAKHFHTMAAMKNHLRRHSRRRSRRHRKRAGGASG-G 684
+ S L+ H++ H G S + + + + HLR S +R +R AS
Sbjct: 723 FGLSSELLLHQKVH-AGGKSSQKSPELGKSSSVLLEHLR--SPLGARPYRCSDCRASFLD 779
Query: 685 REAKLLAAESWTRELEDNE--------GLESPQDPSGESPHGAEGNLESDG 727
R A E+ T+E N L + Q+ GE+P E + +G
Sbjct: 780 RVALTRHQETHTQEKPPNPEDPPPEAVTLSTDQEGEGETPTPTESSSHGEG 830
Score = 143 bits (361), Expect = 1e-33
Identities = 151/613 (24%), Positives = 232/613 (37%), Gaps = 107/613 (17%)
Query: 1218 LINHRQSHQTGHFGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQ 1277
L+ R + + C C K FS L H+RIH R CSECGK+F L HQ
Sbjct: 138 LVQGRPAGAEKPYICNECGKSFSQWSKLLRHQRIHTGERPNTCSECGKSFTQSSHLVQHQ 197
Query: 1278 RVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTY 1335
R H ++P++C CG+ + + +L+ H+R+H TG+ Y C C K +
Sbjct: 198 RTH-------------TGEKPYKCPDCGKCFSWSSNLVQHQRTH-TGEKPYKCTECEKAF 243
Query: 1336 SNRMALKDHQRLHSENRRRRAGRSRRTAVR------------------CALCGRSFPGRG 1377
+ L HQR H+ + + G RR R C CG+ F
Sbjct: 244 TQSTNLIKHQRSHTGEKPYKCGECRRAFYRSSDLIQHQATHTGEKPYKCPECGKRFGQNH 303
Query: 1378 SLERHLREH--EETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPR 1435
+L +H + H E+ R G+ + + LT Q T G +P LE G +
Sbjct: 304 NLLKHQKIHAGEKPYRCTECGKSFI-----QSSELTQHQRTHT---GEKPYECLECG--K 353
Query: 1436 PGERSQSPIRAASSEAPE-PLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSVH 1494
S + I+ + E P PV G S + T + E
Sbjct: 354 SFGHSSTLIKHQRTHLREDPFK--------CPVCGKTFTLSATLLRHQRTHTGE------ 399
Query: 1495 RSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHS-SCSQCGKTYCQSGSLLNHNTNK 1553
P +C G + S N N ++ G C+ CGK++ S +L+ H
Sbjct: 400 -RPYKCPEC---GKSFSVS---SNLINHQRIHRGERPYICADCGKSFIMSSTLIRHQRIH 452
Query: 1554 TDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGH 1611
T + C C K F+ H H + + CP+CGK+F L +H++ H +
Sbjct: 453 TGEKPYKCSDCGKSFIRSSHLIQHRRTHTGEKPYKCPECGKSFSQSSNLITHVRTHMDEN 512
Query: 1612 SQVPAQMEEARDPKAGTGEDQVVLPGQGK--AQEAPSETPRGPGESVERARGGQAVTSMA 1669
V + +A +A E V+ +GK A+ A ++ G G+ + +
Sbjct: 513 LFVCSDCGKA-FLEAHELEQHRVIHERGKTPARRAQGDSLLGLGDP----------SLLT 561
Query: 1670 AEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGLYPCSLCPKLLPNLLSLKNHSRTHTDP 1729
+P +C CG+ + G + HQ+ H G P L+ + R+ P
Sbjct: 562 PPPGAKPHKCLVCGKGFNDEGIFMQHQRIH-IGENPYKNADGLIAHAAPKPPQLRSPRLP 620
Query: 1730 KRHCCSICGKAFRTAA--RLEGHGRVHAPREG--------------PFTCPHCPRHFRRR 1773
R G ++ AA R E G+ P EG + C HC F R
Sbjct: 621 FR------GNSYPGAAEGRAEAPGQPLKPPEGQEGFSQRRGLLSSKTYICSHCGESFLDR 674
Query: 1774 ISFVQHQQQHQEE 1786
+QHQ H E
Sbjct: 675 SVLLQHQLTHGNE 687
Score = 123 bits (309), Expect = 1e-27
Identities = 106/413 (25%), Positives = 160/413 (38%), Gaps = 30/413 (7%)
Query: 1387 EETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRPGERS-----Q 1441
EE+ R+ ++G+ + G A S E L + P + P P S Q
Sbjct: 32 EESPRQESSGEEIIMGDPAQSPESKDST--EMSLERSSQDPSVPQNPPTPLGHSNPLDHQ 89
Query: 1442 SPIRAASSEA-PEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPE--DSVHRSPC 1498
P+ + E P P W W G +S VP + EP + V P
Sbjct: 90 IPLDPPAPEVVPTPSDWTKACEASWQWGALTTWNSPPVVP-----ANEPSLRELVQGRPA 144
Query: 1499 HAGDCQLNGPTLSHMDSWDNRDNSSQLQPGSH-SSCSQCGKTYCQSGSLLNHNTNKTDR- 1556
A + W ++ G ++CS+CGK++ QS L+ H T
Sbjct: 145 GAEKPYICNECGKSFSQWSKLLRHQRIHTGERPNTCSECGKSFTQSSHLVQHQRTHTGEK 204
Query: 1557 -HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQVP 1615
+ C C K F H H + + C +C KAF L H ++H + P
Sbjct: 205 PYKCPDCGKCFSWSSNLVQHQRTHTGEKPYKCTECEKAFTQSTNLIKHQRSHT---GEKP 261
Query: 1616 AQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVER-ARGGQAVTSMAAEDKE 1674
+ E R +A ++ E P + P E +R + + E
Sbjct: 262 YKCGECR--RAFYRSSDLIQHQATHTGEKPYKCP----ECGKRFGQNHNLLKHQKIHAGE 315
Query: 1675 RPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLCPKLLPNLLSLKNHSRTHTDPKRHC 1733
+P+RCT+CG+S+ + L HQ+ HT Y C C K + +L H RTH
Sbjct: 316 KPYRCTECGKSFIQSSELTQHQRTHTGEKPYECLECGKSFGHSSTLIKHQRTHLREDPFK 375
Query: 1734 CSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
C +CGK F +A L H R H E P+ CP C + F + + HQ+ H+ E
Sbjct: 376 CPVCGKTFTLSATLLRHQRTHT-GERPYKCPECGKSFSVSSNLINHQRIHRGE 427
Score = 114 bits (286), Expect = 7e-25
Identities = 61/193 (31%), Positives = 95/193 (49%), Gaps = 29/193 (15%)
Query: 1198 SSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADP 1255
+ ERP +C CG+S+ + L+ H+++H TG + C C K FS +L H+R H
Sbjct: 173 TGERPNTCSECGKSFTQSSHLVQHQRTH-TGEKPYKCPDCGKCFSWSSNLVQHQRTHTGE 231
Query: 1256 RRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLL 1315
+ ++C+EC KAF L HQR H ++P++CG+C R + + L+
Sbjct: 232 KPYKCTECEKAFTQSTNLIKHQRSH-------------TGEKPYKCGECRRAFYRSSDLI 278
Query: 1316 NHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSF 1373
H+ +H TG+ Y CP C K + L HQ++H+ + RC CG+SF
Sbjct: 279 QHQATH-TGEKPYKCPECGKRFGQNHNLLKHQKIHAGEK----------PYRCTECGKSF 327
Query: 1374 PGRGSLERHLREH 1386
L +H R H
Sbjct: 328 IQSSELTQHQRTH 340
Score = 112 bits (280), Expect = 3e-24
Identities = 162/741 (21%), Positives = 273/741 (36%), Gaps = 127/741 (17%)
Query: 705 LESPQDPSGESPHGAEGNLESDGDCLQAESEGDKCGLERDETHFQGDKESGGTGEGLER- 763
L+ P+ ++ GAE E++ + + ES G++ + D K+S T LER
Sbjct: 12 LQGPEQSPNDAHRGAES--ENEEESPRQESSGEEI-IMGDPAQSPESKDS--TEMSLERS 66
Query: 764 -KDASLLDNLDIPGEEGGGTHFCDSLTGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHT 822
+D S+ N P G ++ D +D P+ + + A WQ GA T
Sbjct: 67 SQDPSVPQN---PPTPLGHSNPLDHQIPLDPPAPEVVPTPSDWTKACEA--SWQWGALTT 121
Query: 823 CSD---CGHSFPHATGLLSHRPCHPPGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQ 879
+ + P L+ RP Y C+ C K F L H + H T +
Sbjct: 122 WNSPPVVPANEPSLRELVQGRPAGAEKPYICNECGKSFSQWSKLLRHQRIH-----TGER 176
Query: 880 PFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAE 939
P C CG F ++ + + ++ H+ GE+ P + P +
Sbjct: 177 PNTCSECGKSFT-QSSHLVQHQRTHT-----------GEK-------PYKCPDCGKCFSW 217
Query: 940 LLNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDA 999
N +Q + Y C C + + +L +H +S + + P G A
Sbjct: 218 SSNLVQHQRTHTGEKPYK--CTECEKAFTQSTNLIKHQRSHTG-----EKPYKCGECRRA 270
Query: 1000 MEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGK 1059
D + ++ G G G + + + + A +P+RC +CGK
Sbjct: 271 FYRSSDLIQHQATHT----GEKPYKCPECGKRFGQNHNLLKHQKI-HAGEKPYRCTECGK 325
Query: 1060 TYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPI-PE 1116
++ L H++ H TG+ + C C + + + + H R H R +P P+ +
Sbjct: 326 SFIQSSELTQHQRTH-TGEKPYECLECGKSFGHSSTLIKHQRTHLR---EDPFKCPVCGK 381
Query: 1117 AAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKV----EPLEEVARVKEEVW 1172
S + +P E G + L ++ P K +
Sbjct: 382 TFTLSATLLRHQRTHTGERPYKCPECGKSFSVSSNLINHQRIHRGERPYICADCGKSFIM 441
Query: 1173 EETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--F 1230
T ++ + I + E+P+ C CG+S+ + LI HR++H TG +
Sbjct: 442 SSTLIRHQRIH--------------TGEKPYKCSDCGKSFIRSSHLIQHRRTH-TGEKPY 486
Query: 1231 GCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTR 1290
C C K FS +L H R H D F CS+CGKAF +L H+ +H RG R
Sbjct: 487 KCPECGKSFSQSSNLITHVRTHMDENLFVCSDCGKAFLEAHELEQHRVIH--ERGKTPAR 544
Query: 1291 KATRED----------------RPFRCGQCGRTYRHAGSLLNHRRSHETGQ--------- 1325
+A + +P +C CG+ + G + H+R H G+
Sbjct: 545 RAQGDSLLGLGDPSLLTPPPGAKPHKCLVCGKGFNDEGIFMQHQRIH-IGENPYKNADGL 603
Query: 1326 --YSCPTCPKTYSNRMALKDHQRLHSENRRRRA------------GRSRRTAVR------ 1365
++ P P+ S R+ + + + R A G S+R +
Sbjct: 604 IAHAAPKPPQLRSPRLPFRGNSYPGAAEGRAEAPGQPLKPPEGQEGFSQRRGLLSSKTYI 663
Query: 1366 CALCGRSFPGRGSLERHLREH 1386
C+ CG SF R L +H H
Sbjct: 664 CSHCGESFLDRSVLLQHQLTH 684
Score = 105 bits (263), Expect = 3e-22
Identities = 86/327 (26%), Positives = 115/327 (35%), Gaps = 68/327 (20%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C++CGK++ QS L H T + CL C K F + H H+ F CP C
Sbjct: 320 CTECGKSFIQSSELTQHQRTHTGEKPYECLECGKSFGHSSTLIKHQRTHLREDPFKCPVC 379
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSET-- 1648
GK F L H + H TGE P GK+ S
Sbjct: 380 GKTFTLSATLLRHQRTH--------------------TGERPYKCPECGKSFSVSSNLIN 419
Query: 1649 ----PRGPGESVERARGGQAVTSMAA------EDKERPFRCTQCGRSYRHAGSLLNHQKA 1698
RG + G + S E+P++C+ CG+S+ + L+ H++
Sbjct: 420 HQRIHRGERPYICADCGKSFIMSSTLIRHQRIHTGEKPYKCSDCGKSFIRSSHLIQHRRT 479
Query: 1699 HTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVH--- 1754
HT Y C C K +L H RTH D CS CGKAF A LE H +H
Sbjct: 480 HTGEKPYKCPECGKSFSQSSNLITHVRTHMDENLFVCSDCGKAFLEAHELEQHRVIHERG 539
Query: 1755 -----------------------APREGPFTCPHCPRHFRRRISFVQHQQQHQEEWTVAG 1791
P P C C + F F+QHQ+ H E
Sbjct: 540 KTPARRAQGDSLLGLGDPSLLTPPPGAKPHKCLVCGKGFNDEGIFMQHQRIHIGENPYKN 599
Query: 1792 SGAPVAPVTGRGDLPLPPPPTPTTPLL 1818
+ +A P PP +P L
Sbjct: 600 ADGLIAHAA-------PKPPQLRSPRL 619
Score = 75.5 bits (184), Expect = 4e-13
Identities = 83/368 (22%), Positives = 119/368 (32%), Gaps = 98/368 (26%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
CS CGK++ +S L+ H T + C C K F +H H+D F C DC
Sbjct: 460 CSDCGKSFIRSSHLIQHRRTHTGEKPYKCPECGKSFSQSSNLITHVRTHMDENLFVCSDC 519
Query: 1591 GKAFESHQELASHLQAH---------ARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKA 1641
GKAF EL H H A+G S + P G + ++ G+G
Sbjct: 520 GKAFLEAHELEQHRVIHERGKTPARRAQGDSLLGLGDPSLLTPPPGAKPHKCLVCGKGFN 579
Query: 1642 QE--------------------------APS----ETPR-----------------GPGE 1654
E AP +PR PG+
Sbjct: 580 DEGIFMQHQRIHIGENPYKNADGLIAHAAPKPPQLRSPRLPFRGNSYPGAAEGRAEAPGQ 639
Query: 1655 SVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGLYPCSLCPKLLP 1714
++ G + + + + C+ CG S+ LL HQ H P L P
Sbjct: 640 PLKPPEGQEGFSQRRGLLSSKTYICSHCGESFLDRSVLLQHQLTHGNEK------PFLFP 693
Query: 1715 NL---LSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHA--------PREG---- 1759
+ L K C C ++F ++ L H +VHA P G
Sbjct: 694 DYRIGLGEGAGPSPFLSGKPFKCPECKQSFGLSSELLLHQKVHAGGKSSQKSPELGKSSS 753
Query: 1760 -------------PFTCPHCPRHFRRRISFVQHQQQHQEEWTVAGSGAPVAPVT------ 1800
P+ C C F R++ +HQ+ H +E P VT
Sbjct: 754 VLLEHLRSPLGARPYRCSDCRASFLDRVALTRHQETHTQEKPPNPEDPPPEAVTLSTDQE 813
Query: 1801 GRGDLPLP 1808
G G+ P P
Sbjct: 814 GEGETPTP 821
Score = 63.5 bits (153), Expect = 2e-09
Identities = 101/452 (22%), Positives = 152/452 (33%), Gaps = 92/452 (20%)
Query: 821 HTCSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQ 879
+ CSDCG SF ++ L+ HR H Y+C C K F L +H + H
Sbjct: 458 YKCSDCGKSFIRSSHLIQHRRTHTGEKPYKCPECGKSFSQSSNLITHVRTH-----MDEN 512
Query: 880 PFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEE-EGVAEAAPARSPPLQLSEA 938
F+C CG F + L + + G T +G+ G+ + + PP
Sbjct: 513 LFVCSDCGKAF--LEAHELEQHRVIHERGKTPARRAQGDSLLGLGDPSLLTPPP------ 564
Query: 939 ELLNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQ--------SQSSGTTADKAP 990
H C CG+ ++D G +H + + G A AP
Sbjct: 565 ---------------GAKPHKCLVCGKGFNDEGIFMQHQRIHIGENPYKNADGLIAHAAP 609
Query: 991 SPLGVAGDAMEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEA--Q 1048
P + + +S G K EG Q G S
Sbjct: 610 KPPQLRSPRLPFRGNSYPGAAEGRAEAPGQPLKPPEG-----------QEGFSQRRGLLS 658
Query: 1049 PRPFRCNQCGKTYRHGGSLVNHRKIH-QTGDFLCPVCSRCYPNLAAYRNHLRNHP-RCKG 1106
+ + C+ CG+++ L+ H+ H FL P A L P +C
Sbjct: 659 SKTYICSHCGESFLDRSVLLQHQLTHGNEKPFLFPDYRIGLGEGAGPSPFLSGKPFKCPE 718
Query: 1107 SEPQVGPIPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAE-VEKLQEELKVEP----- 1160
+ G SSEL + G Q E G + +E L+ L P
Sbjct: 719 CKQSFGL------SSELLLHQKVHAGGKSSQKSPELGKSSSVLLEHLRSPLGARPYRCSD 772
Query: 1161 -----LEEVA--RVKEEVWEETTVKGEEIEPR---LETAEKG-----CQTEASS------ 1199
L+ VA R +E +E E+ P L T ++G TE+SS
Sbjct: 773 CRASFLDRVALTRHQETHTQEKPPNPEDPPPEAVTLSTDQEGEGETPTPTESSSHGEGQN 832
Query: 1200 ------ERPFSCEVCGRSYKHAGSLINHRQSH 1225
E+P+ C CG + +L+ HR H
Sbjct: 833 PKTLVEEKPYLCPECGAGFTEVAALLLHRSCH 864
>gi|6005976 zinc finger protein 208 [Homo sapiens]
Length = 1167
Score = 186 bits (471), Expect = 2e-46
Identities = 176/776 (22%), Positives = 291/776 (37%), Gaps = 115/776 (14%)
Query: 1050 RPFRCNQCGKTYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGS 1107
+P++C +CGK Y+ +L H+KIH TG+ + C C + + + H H K
Sbjct: 367 KPYKCEECGKAYKWPSTLSYHKKIH-TGEKPYKCEECGKGFSMFSILTKHEVIHTGEKPY 425
Query: 1108 EPQVGPIPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARV 1167
+ + S+ ++ I G + P E G G + L K+ +E+ +
Sbjct: 426 KCEECGKAFNWSSNLMEHKKIHTGET--PYKCEECGKGFSWSSTLSYHKKIHTVEKPYKC 483
Query: 1168 KE--EVWEETTVKGEEIEPRLETAEKGCQTEA------------------SSERPFSCEV 1207
+E + + ++ + + R+ T EK + E + E+P+ C+
Sbjct: 484 EECGKAFNQSAILIKH--KRIHTGEKPYKCEECGKTFSKVSTLTTHKAIHAGEKPYKCKE 541
Query: 1208 CGRSYKHAGSLINHRQSHQTGH-FGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKA 1266
CG+++ +L H+ H + C+ C K FS L H+ IH + ++C ECGKA
Sbjct: 542 CGKTFIKVSTLTTHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGKA 601
Query: 1267 FRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ- 1325
F L H+R+H ++P++C +CG+++ L H+ H TG+
Sbjct: 602 FNWSSNLMEHKRIH-------------TGEKPYKCEECGKSFSTFSVLTKHKVIH-TGEK 647
Query: 1326 -YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLR 1384
Y C C K Y L H+++H+ + +C CG++F L +H R
Sbjct: 648 PYKCEECGKAYKWSSTLSYHKKIHTVEK----------PYKCEECGKAFNRSAILIKHKR 697
Query: 1385 EHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRPGERSQSPI 1444
H T+ +P + T + + LT + + G +P E G +
Sbjct: 698 IH--TDEKPYKCE-ECGKTFSKVSTLTTHKAIH---AGEKPYKCKECGKAFSKFSILTKH 751
Query: 1445 RAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDS-------VHRSP 1497
+ + GKA WP L H + + EE
Sbjct: 752 KVIHTGEKPYKCEECGKAYKWP--STLSYHKKIHTGEKPYKCEECGKGFSMFSILTKHEV 809
Query: 1498 CHAGD----CQLNGPTLSHMDSWDNRDNSSQLQPGSHSSCSQCGKTYCQSGSLLNHNTNK 1553
H G+ C+ G S + + + + C CGK Y L H
Sbjct: 810 IHTGEKPYKCEECGKAFSWLSVFSKHKKTHAGE--KFYKCEACGKAYNTFSILTKHKVIH 867
Query: 1554 TDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGH 1611
T + C C K F H H + C +C KAF L H HA
Sbjct: 868 TGEKPYKCEECGKAFNWSSNLMEHKKIHTGETPYKCEECDKAFSWPSSLTEHKATHA--- 924
Query: 1612 SQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVERARGGQAVTSMAAE 1671
+ P + EE GKA PS + A
Sbjct: 925 GEKPYKCEEC-----------------GKAFSWPS----------------RLTEHKATH 951
Query: 1672 DKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLCPKLLPNLLSLKNHSRTHTDPK 1730
E P++C +CG+++ + +L+ H++ HT Y C C K L H HT K
Sbjct: 952 AGEEPYKCEECGKAFNWSSNLMEHKRIHTGEKPYKCEECGKSFSTFSILTKHKVIHTGEK 1011
Query: 1731 RHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
+ C CGKA++ ++ L H ++H E P+ C C + F +H+ H E
Sbjct: 1012 PYKCEECGKAYKWSSTLSYHKKIHTV-EKPYKCEECGKGFVMFSILAKHKVIHTGE 1066
Score = 182 bits (462), Expect = 3e-45
Identities = 208/902 (23%), Positives = 338/902 (37%), Gaps = 159/902 (17%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C + F L++H+ ++H +PY+C++CG+ Y+ P +L H++
Sbjct: 343 CKECGKAFSKFSILTKHK-VIHTGE-----------KPYKCEECGKAYKWPSTLSYHKKI 390
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHLQGETVSTDSW 127
H TG P C CGK FS L H H E P+ E +W
Sbjct: 391 H-TGEKPYKCEECGKGFSMFSILTKHEVIHTGE-------------KPYKCEECGKAFNW 436
Query: 128 GQRLGSSEGWENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGADG 186
SS E++ HT ETP CE + S T L ++ P +
Sbjct: 437 -----SSNLMEHKKIHTGETPYKCEECGKGFSWSST---LSYHKKIHTVEKPYK---CEE 485
Query: 187 WGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPA--EEERRYKCSQC 244
G + N + + I + + + Y E + A E+ YKC +C
Sbjct: 486 CGKAFNQS---AILIKHKRIHTGEKPYKCEECGKTFSKVSTLTTHKAIHAGEKPYKCKEC 542
Query: 245 GKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVF 303
GKT+ +LT H+ H Y C C K FS L H +H +PY C C + F
Sbjct: 543 GKTFIKVSTLTTHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGKAF 602
Query: 304 RLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSGEL 363
L+EH++ H GE+ + EE G S+ L ++++ +GE
Sbjct: 603 NWSSNLMEHKRIHTGEKPY-KCEECG-------KSFSTFSVLTKHKVIH-------TGE- 646
Query: 364 EDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQT-GVYPCSLCSKQLFNAAALKNHVRA 422
+P++C +CG+ Y+ + +L H+K H Y C C K +A L H R
Sbjct: 647 --------KPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKAFNRSAILIKHKRI 698
Query: 423 HHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVN 482
H + E + L TTHK +PYKC ECG+A+ L
Sbjct: 699 HTDEKPYKCEECGKTFSKVSTL---TTHK-----AIHAGEKPYKCKECGKAFSKFSILTK 750
Query: 483 HRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHCKAARRSADIGAEGAPSHLKVELPPD 540
H+ H TGE Y+C C + Y L H ++H + +G S + +
Sbjct: 751 HKVIH-TGEKPYKCEECGKAYKWPSTLSYHKKIHTGEKPYKCEECGKGF-SMFSILTKHE 808
Query: 541 PVEAEAAPHTDQDHVCKHEEEATDITPAADKTAA----HICSICGLLFEDAESLERHGLT 596
+ P+ ++ C + KT A + C CG + L +H +
Sbjct: 809 VIHTGEKPYKCEE--CGKAFSWLSVFSKHKKTHAGEKFYKCEACGKAYNTFSILTKHKVI 866
Query: 597 HGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFH 654
H GEK + C +CGK++ S +L+ H++ H TG+ + C C K F
Sbjct: 867 H-TGEK-------------PYKCEECGKAFNWSSNLMEHKKIH-TGETPYKCEECDKAFS 911
Query: 655 TMAAMKNHLRRHSRRRSRRHRKRAGGASGGREAKLLAAESWTRELEDNEGLESPQDPSGE 714
+++ H H+ + + + A SW L +++ +GE
Sbjct: 912 WPSSLTEHKATHAGEKPYKCEECG------------KAFSWPSRLTEHKATH-----AGE 954
Query: 715 SPHGAEGNLESDGDCLQAESEGDKCGLERDETHFQGDKESGGTGEGLERKDASLLDNLDI 774
P+ E +C +A + +E H G+K G S+L +
Sbjct: 955 EPYKCE-------ECGKAFNWSSNL-MEHKRIH-TGEKPYKCEECGKSFSTFSILTKHKV 1005
Query: 775 PGEEGGGTHFCDSLTGVDEDQKPATGQPNSSSHSANAVTGWQ-----AGAAHTCSDCGHS 829
+ +KP + ++ ++ + + C +CG
Sbjct: 1006 ----------------IHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKG 1049
Query: 830 FPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGM 888
F + L H+ H +Y+C C K + LR H + H T +P+ C CG
Sbjct: 1050 FVMFSILAKHKVIHTGEKLYKCEECGKAYKWPSTLRYHKKIH-----TGEKPYKCEECGK 1104
Query: 889 IF 890
F
Sbjct: 1105 AF 1106
Score = 166 bits (421), Expect = 1e-40
Identities = 144/608 (23%), Positives = 232/608 (38%), Gaps = 92/608 (15%)
Query: 1198 SSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADP 1255
+ E+P+ C+ CG+++ L H+ H TG + C+ C K F+ L H+ IH
Sbjct: 224 TGEKPYRCKECGKAFSKFSILTKHKVIH-TGEKSYKCEECGKAFNQSAILTKHKIIHTGE 282
Query: 1256 RRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLL 1315
+ +C ECGKAF L +H+ +H ++P++C +CG+ + +L+
Sbjct: 283 KPNKCEECGKAFSKVSTLTTHKAIH-------------AGEKPYKCKECGKAFSKVSTLI 329
Query: 1316 NHRRSHETGQ-YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFP 1374
H+ H + Y C C K +S L H+ +H+ + +C CG+++
Sbjct: 330 THKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTGEK----------PYKCEECGKAYK 379
Query: 1375 GRGSLERHLREHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVP 1434
+L H + H T +P + G + LT + + T G +P E G
Sbjct: 380 WPSTLSYHKKIH--TGEKPYKCEECGKGFSMFSI-LTKHEVIHT---GEKPYKCEECGKA 433
Query: 1435 -RPGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSV 1493
+ + E P GK W L H + + EE +
Sbjct: 434 FNWSSNLMEHKKIHTGETPYKCE-ECGKGFSW--SSTLSYHKKIHTVEKPYKCEECGKAF 490
Query: 1494 HRSP-------CHAGD----CQLNGPTLSHMDSWDNRDNSSQLQPGSHS-SCSQCGKTYC 1541
++S H G+ C+ G T S + + + G C +CGKT+
Sbjct: 491 NQSAILIKHKRIHTGEKPYKCEECGKTFSKVSTLTTH---KAIHAGEKPYKCKECGKTFI 547
Query: 1542 QSGSLLNHNT-NKTDRHY-CLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQE 1599
+ +L H + ++ Y C C K F H H + + C +CGKAF
Sbjct: 548 KVSTLTTHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGKAFNWSSN 607
Query: 1600 LASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVERA 1659
L H + H TGE GK+ S +
Sbjct: 608 LMEHKRIH--------------------TGEKPYKCEECGKSFSTFSVLTK--------- 638
Query: 1660 RGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLS 1718
E+P++C +CG++Y+ + +L H+K HT Y C C K
Sbjct: 639 -------HKVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKAFNRSAI 691
Query: 1719 LKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQ 1778
L H R HTD K + C CGK F + L H +HA E P+ C C + F + +
Sbjct: 692 LIKHKRIHTDEKPYKCEECGKTFSKVSTLTTHKAIHA-GEKPYKCKECGKAFSKFSILTK 750
Query: 1779 HQQQHQEE 1786
H+ H E
Sbjct: 751 HKVIHTGE 758
Score = 161 bits (408), Expect = 5e-39
Identities = 201/951 (21%), Positives = 333/951 (35%), Gaps = 229/951 (24%)
Query: 7 SLSCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNH 66
S C +C + F L++H+ ++H +P +C++CG+ + +L H
Sbjct: 256 SYKCEECGKAFNQSAILTKHK-IIHTGE-----------KPNKCEECGKAFSKVSTLTTH 303
Query: 67 RRTHE-TGLFPCTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHLQGETVSTD 125
+ H + C CGK FS L +H HA E +P + KE ++ T
Sbjct: 304 KAIHAGEKPYKCKECGKAFSKVSTLITHKAIHAGE-----KPYKCKECGKAFSKFSILT- 357
Query: 126 SWGQRLGSSEGWENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGA 184
+++ HT E P CE G P+ H G +
Sbjct: 358 ------------KHKVIHTGEKPYKCEE-------CGKAYKWPSTLSYHKKIHTGEK--- 395
Query: 185 DGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQC 244
P ++ L + V TG E+ YKC +C
Sbjct: 396 -------------PYKCEECGKGFSMFSILTKHEVIHTG------------EKPYKCEEC 430
Query: 245 GKTYKHAGSLTNHRQSHTLGI-YPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVF 303
GK + + +L H++ HT Y C C K FS L H ++H +PY C C + F
Sbjct: 431 GKAFNWSSNLMEHKKIHTGETPYKCEECGKGFSWSSTLSYHKKIHTVEKPYKCEECGKAF 490
Query: 304 RLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSGEL 363
L++H++ H GE+
Sbjct: 491 NQSAILIKHKRIHTGEK------------------------------------------- 507
Query: 364 EDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQ-TGVYPCSLCSKQLFNAAALKNH--V 420
P++C +CG+T+ +L H+ H Y C C K + L H +
Sbjct: 508 ---------PYKCEECGKTFSKVSTLTTHKAIHAGEKPYKCKECGKTFIKVSTLTTHKAI 558
Query: 421 RAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSL 480
A +P + E G+ + L + H E +PYKC ECG+A+ +L
Sbjct: 559 HAGEKPYK-CKECGKAFSKFSILTKHKVIHTGE---------KPYKCEECGKAFNWSSNL 608
Query: 481 VNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHC-----------KAARRSADIGAE 527
+ H+ H TGE Y+C C + + L H +H KA + S+ +
Sbjct: 609 MEHKRIH-TGEKPYKCEECGKSFSTFSVLTKHKVIHTGEKPYKCEECGKAYKWSSTLS-- 665
Query: 528 GAPSHLKVELPPDPVEAE--AAPHTDQDHVCKHEEEATDITPAADKTAAHICSICGLLFE 585
H K+ P + E + KH+ TD P + C CG F
Sbjct: 666 ---YHKKIHTVEKPYKCEECGKAFNRSAILIKHKRIHTDEKP-------YKCEECGKTFS 715
Query: 586 DAESLERHGLTHGAGEKEN---------------SRTETTMSPPRAFACRDCGKSYRHSG 630
+L H H AGEK ++ + + + + C +CGK+Y+
Sbjct: 716 KVSTLTTHKAIH-AGEKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGKAYKWPS 774
Query: 631 SLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHSRRRS----------------R 672
+L H++ H TG+ + C C K F + + H H+ +
Sbjct: 775 TLSYHKKIH-TGEKPYKCEECGKGFSMFSILTKHEVIHTGEKPYKCEECGKAFSWLSVFS 833
Query: 673 RHRKRAGGASGGREAKLLAAESWTRELEDNEGLESPQDPSGESPHGAEGNLESDGDCLQA 732
+H+K G + A + L ++ + +GE P+ E +C +A
Sbjct: 834 KHKKTHAGEKFYKCEACGKAYNTFSILTKHKVIH-----TGEKPYKCE-------ECGKA 881
Query: 733 ESEGDKCGLERDETHFQGDKESGGTGEGLERKDASLLDNLDIPGEEGGGTHFCDSLTGVD 792
+ +E + H +G T E D + + E TH + +
Sbjct: 882 FNWSSNL-MEHKKIH------TGETPYKCEECDKAFSWPSSL--TEHKATHAGEKPYKCE 932
Query: 793 EDQKPATGQPNSSSHSANAVTGWQAG-AAHTCSDCGHSFPHATGLLSHRPCHP-PGIYQC 850
E K + + H A AG + C +CG +F ++ L+ H+ H Y+C
Sbjct: 933 ECGKAFSWPSRLTEHKAT-----HAGEEPYKCEECGKAFNWSSNLMEHKRIHTGEKPYKC 987
Query: 851 SLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHRR 901
C K F + L H H T +P+ C CG + + H++
Sbjct: 988 EECGKSFSTFSILTKHKVIH-----TGEKPYKCEECGKAYKWSSTLSYHKK 1033
Score = 158 bits (399), Expect = 5e-38
Identities = 160/675 (23%), Positives = 254/675 (37%), Gaps = 138/675 (20%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C + F L++H+ ++H +PY+C++CG+ + +L+ H+R
Sbjct: 567 CKECGKAFSKFSILTKHK-VIHTGE-----------KPYKCEECGKAFNWSSNLMEHKRI 614
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHLQGETVSTDSW 127
H TG P C CGK FS L H H E P+ E W
Sbjct: 615 H-TGEKPYKCEECGKSFSTFSVLTKHKVIHTGE-------------KPYKCEECGKAYKW 660
Query: 128 GQRLGSSEGWENQTKHTEETP----DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDG 183
L ++ HT E P +C + A + + T ++ G
Sbjct: 661 SSTLSY-----HKKIHTVEKPYKCEECGKAFNRSAILIKHKRIHTDEKPYKCEECGKTFS 715
Query: 184 ADGWGPSTNSARAPPLPIPASSLLSNLEQY--LAESVVNFTGGQEPTQSPPAEEERRYKC 241
+ + A P ++ L + V TG E+ YKC
Sbjct: 716 KVSTLTTHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTG------------EKPYKC 763
Query: 242 SQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCP 300
+CGK YK +L+ H++ HT Y C C K FS L H +H +PY C C
Sbjct: 764 EECGKAYKWPSTLSYHKKIHTGEKPYKCEECGKGFSMFSILTKHEVIHTGEKPYKCEECG 823
Query: 301 RVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTS 360
+ F +H+++H GE+ + E+ + +L + T
Sbjct: 824 KAFSWLSVFSKHKKTHAGEKF--------------YKCEACGKAYNTFSILTKHKVIHT- 868
Query: 361 GELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTGV--YPCSLCSKQLFNAAALKN 418
GE +P++C +CG+ + + +L+ H+K H TG Y C C K ++L
Sbjct: 869 GE---------KPYKCEECGKAFNWSSNLMEHKKIH-TGETPYKCEECDKAFSWPSSLTE 918
Query: 419 HVRAH--HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRH 476
H H +P + E G+ P+ L + TH EE PYKC ECG+A+
Sbjct: 919 HKATHAGEKPYK-CEECGKAFSWPSRLTEHKATHAGEE---------PYKCEECGKAFNW 968
Query: 477 RGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHCKAARRSADIGAEGAPSHLK 534
+L+ H+ H TGE Y+C C + + L H +H
Sbjct: 969 SSNLMEHKRIH-TGEKPYKCEECGKSFSTFSILTKHKVIHTGEK---------------- 1011
Query: 535 VELPPDPVEAEAAPHTDQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHG 594
P E + + H++ T P + C CG F L +H
Sbjct: 1012 ----PYKCEECGKAYKWSSTLSYHKKIHTVEKP-------YKCEECGKGFVMFSILAKHK 1060
Query: 595 LTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKH 652
+ H GEK + C +CGK+Y+ +L H++ H TG+ + C C K
Sbjct: 1061 VIH-TGEK-------------LYKCEECGKAYKWPSTLRYHKKIH-TGEKPYKCEECGKA 1105
Query: 653 FHTMAAMKNHLRRHS 667
F T + + H H+
Sbjct: 1106 FSTFSILTKHKVIHT 1120
Score = 140 bits (352), Expect = 1e-32
Identities = 132/544 (24%), Positives = 210/544 (38%), Gaps = 109/544 (20%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C + F + L+ H+ + + +PY+C++CG+ + L H+
Sbjct: 707 CEECGKTFSKVSTLTTHKAI------------HAGEKPYKCKECGKAFSKFSILTKHKVI 754
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHLQGETVSTDSW 127
H TG P C CGK + P L H + H E +P + +E ++ T
Sbjct: 755 H-TGEKPYKCEECGKAYKWPSTLSYHKKIHTGE-----KPYKCEECGKGFSMFSILT--- 805
Query: 128 GQRLGSSEGWENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGADG 186
+++ HT E P CE + +W + ++ ++ A + A G
Sbjct: 806 ----------KHEVIHTGEKPYKCEEC----GKAFSWLSVFSKHKKTHAGEKFYKCEACG 851
Query: 187 WGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGK 246
+T S L + V TG E+ YKC +CGK
Sbjct: 852 KAYNTFSI-------------------LTKHKVIHTG------------EKPYKCEECGK 880
Query: 247 TYKHAGSLTNHRQSHTLGI-YPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRL 305
+ + +L H++ HT Y C C K FS +L H HA +PY C C + F
Sbjct: 881 AFNWSSNLMEHKKIHTGETPYKCEECDKAFSWPSSLTEHKATHAGEKPYKCEECGKAFSW 940
Query: 306 PRELLEHQQSHEGERQEP----------RWEEKGMPTTNGHTDESSQDQLPSAQMLNGSA 355
P L EH+ +H GE EP W M HT E + + +
Sbjct: 941 PSRLTEHKATHAGE--EPYKCEECGKAFNWSSNLMEHKRIHTGEKPYKCEECGKSFS-TF 997
Query: 356 ELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQT-GVYPCSLCSKQLFNAA 414
+ T ++ +G +P++C +CG+ Y+ + +L H+K H Y C C K +
Sbjct: 998 SILTKHKVIHTG---EKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKGFVMFS 1054
Query: 415 ALKNHVRAHHRPR-QGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRA 473
L H H + E G+ P+ L + H E +PYKC ECG+A
Sbjct: 1055 ILAKHKVIHTGEKLYKCEECGKAYKWPSTLRYHKKIHTGE---------KPYKCEECGKA 1105
Query: 474 YRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHCKAARRSADIGAEGAPS 531
+ L H+ H TGE Y+C C + + L H ++H G P+
Sbjct: 1106 FSTFSILTKHKVIH-TGEKPYKCEECGKAFSWLSVFSKHKKIH---------TGVPNPPT 1155
Query: 532 HLKV 535
H K+
Sbjct: 1156 HKKI 1159
Score = 138 bits (347), Expect = 6e-32
Identities = 124/483 (25%), Positives = 198/483 (40%), Gaps = 87/483 (18%)
Query: 236 ERRYKCSQCGKTYKHAGSLTNHRQSHTLGIYP--CAICFKEFSNLMALKNHSRLHAQYRP 293
E+ YKC +CGK + + LT H+ HT G P C C K FS + L H +HA +P
Sbjct: 254 EKSYKCEECGKAFNQSAILTKHKIIHT-GEKPNKCEECGKAFSKVSTLTTHKAIHAGEKP 312
Query: 294 YHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNG 353
Y C C + F L+ H+ H GE+ + +E G +
Sbjct: 313 YKCKECGKAFSKVSTLITHKAIHAGEKPY-KCKECGKAFS-------------------- 351
Query: 354 SAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLF 411
+ T ++ +G +P++C +CG+ Y+ +L H+K H TG Y C C K
Sbjct: 352 KFSILTKHKVIHTG---EKPYKCEECGKAYKWPSTLSYHKKIH-TGEKPYKCEECGKGFS 407
Query: 412 NAAALKNHVRAH--HRPRQ----GVGENGQPS-VPPAPLLLAETTHKEEE-----DPTTT 459
+ L H H +P + G N + + + ET +K EE ++T
Sbjct: 408 MFSILTKHEVIHTGEKPYKCEECGKAFNWSSNLMEHKKIHTGETPYKCEECGKGFSWSST 467
Query: 460 LDH--------RPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRN 509
L + +PYKC ECG+A+ L+ H+ H TGE Y+C C + + + L
Sbjct: 468 LSYHKKIHTVEKPYKCEECGKAFNQSAILIKHKRIH-TGEKPYKCEECGKTFSKVSTLTT 526
Query: 510 HVRVH-------CKAARRSADIGAEGAPSHLKVELPPDPVEAE--AAPHTDQDHVCKHEE 560
H +H CK ++ I +H + P + + + + KH+
Sbjct: 527 HKAIHAGEKPYKCKECGKTF-IKVSTLTTHKAIHAGEKPYKCKECGKAFSKFSILTKHKV 585
Query: 561 EATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEK-----ENSRTETTMS--- 612
T P + C CG F + +L H H GEK E ++ +T S
Sbjct: 586 IHTGEKP-------YKCEECGKAFNWSSNLMEHKRIH-TGEKPYKCEECGKSFSTFSVLT 637
Query: 613 -------PPRAFACRDCGKSYRHSGSLINHRQTHQT-GDFSCGACAKHFHTMAAMKNHLR 664
+ + C +CGK+Y+ S +L H++ H + C C K F+ A + H R
Sbjct: 638 KHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKAFNRSAILIKHKR 697
Query: 665 RHS 667
H+
Sbjct: 698 IHT 700
Score = 135 bits (340), Expect = 4e-31
Identities = 125/589 (21%), Positives = 226/589 (38%), Gaps = 93/589 (15%)
Query: 821 HTCSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQ 879
+ C +CG +F + L H+ H Y+C C K F+ L H H T +
Sbjct: 229 YRCKECGKAFSKFSILTKHKVIHTGEKSYKCEECGKAFNQSAILTKHKIIH-----TGEK 283
Query: 880 PFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEA- 938
P C CG F + H+ A A P + E
Sbjct: 284 PNKCEECGKAFSKVSTLTTHK------------------------AIHAGEKPYKCKECG 319
Query: 939 ELLNQLQREV--EALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVA 996
+ +++ + +A+ + + C CG+ + L +H + + P
Sbjct: 320 KAFSKVSTLITHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTG-----EKPYKCEEC 374
Query: 997 GDAMEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQ 1056
G A + S L +GE + G G + I ++ +P++C +
Sbjct: 375 GKAYKW--PSTLSYHKKIHTGEKPYKCEECGKGFSM---FSILTKHEVIHTGEKPYKCEE 429
Query: 1057 CGKTYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPI 1114
CGK + +L+ H+KIH TG+ + C C + + + H + H K + +
Sbjct: 430 CGKAFNWSSNLMEHKKIH-TGETPYKCEECGKGFSWSSTLSYHKKIHTVEKPYKCE--EC 486
Query: 1115 PEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKEEVWEE 1174
+A S + + KP E G ++V L + E+ + KE
Sbjct: 487 GKAFNQSAILIKHKRIHTGEKPYKCEECGKTFSKVSTLTTHKAIHAGEKPYKCKECGKTF 546
Query: 1175 TTVKGEEIEPRLETAEKGCQTEA------------------SSERPFSCEVCGRSYKHAG 1216
V + EK + + + E+P+ CE CG+++ +
Sbjct: 547 IKVSTLTTHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGKAFNWSS 606
Query: 1217 SLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLA 1274
+L+ H++ H TG + C+ C K FS L H+ IH + ++C ECGKA++ L+
Sbjct: 607 NLMEHKRIH-TGEKPYKCEECGKSFSTFSVLTKHKVIHTGEKPYKCEECGKAYKWSSTLS 665
Query: 1275 SHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRSH-ETGQYSCPTCPK 1333
H+++H ++P++C +CG+ + + L+ H+R H + Y C C K
Sbjct: 666 YHKKIH-------------TVEKPYKCEECGKAFNRSAILIKHKRIHTDEKPYKCEECGK 712
Query: 1334 TYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERH 1382
T+S L H+ +H+ + +C CG++F L +H
Sbjct: 713 TFSKVSTLTTHKAIHAGEK----------PYKCKECGKAFSKFSILTKH 751
Score = 134 bits (337), Expect = 8e-31
Identities = 127/584 (21%), Positives = 223/584 (38%), Gaps = 67/584 (11%)
Query: 821 HTCSDCGHSFPHATGLLSHRPCHPPGI-YQCSLCPKEFDSLPALRSHFQNHRPGEATSAQ 879
+ C +CG +F ++ L+ H+ H Y+C C K F L H + H T +
Sbjct: 425 YKCEECGKAFNWSSNLMEHKKIHTGETPYKCEECGKGFSWSSTLSYHKKIH-----TVEK 479
Query: 880 PFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVA-----EAAPARSPPLQ 934
P+ C CG F A H+R H+ + E V+ +A A P +
Sbjct: 480 PYKCEECGKAFNQSAILIKHKR-IHTGEKPYKCEECGKTFSKVSTLTTHKAIHAGEKPYK 538
Query: 935 LSEAE---LLNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPS 991
E + +A+ + + C CG+ + L +H + + P
Sbjct: 539 CKECGKTFIKVSTLTTHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTG-----EKPY 593
Query: 992 PLGVAGDAMEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRP 1051
G A + + +++ G E G + + ++ +P
Sbjct: 594 KCEECGKAFNWSSNLMEHKRIHT----GEKPYKCEECGKSFS-TFSVLTKHKVIHTGEKP 648
Query: 1052 FRCNQCGKTYRHGGSLVNHRKIHQT-GDFLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQ 1110
++C +CGK Y+ +L H+KIH + C C + + A H R H K +
Sbjct: 649 YKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKAFNRSAILIKHKRIHTDEKPYK-- 706
Query: 1111 VGPIPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKEE 1170
E G + +V + ++K H E+ E K + + +V E+
Sbjct: 707 ----CEECGKTFSKVSTLT---THKAIHAGEKPYKCKECGKAFSKFSILTKHKVIHTGEK 759
Query: 1171 VWEETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH- 1229
++ P + K T E+P+ CE CG+ + L H H TG
Sbjct: 760 PYKCEECGKAYKWPSTLSYHKKIHT---GEKPYKCEECGKGFSMFSILTKHEVIH-TGEK 815
Query: 1230 -FGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGG 1288
+ C+ C K FS L H++ HA + ++C CGKA+ L H+ +H
Sbjct: 816 PYKCEECGKAFSWLSVFSKHKKTHAGEKFYKCEACGKAYNTFSILTKHKVIH-------- 867
Query: 1289 TRKATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQR 1346
++P++C +CG+ + + +L+ H++ H TG+ Y C C K +S +L +H+
Sbjct: 868 -----TGEKPYKCEECGKAFNWSSNLMEHKKIH-TGETPYKCEECDKAFSWPSSLTEHKA 921
Query: 1347 LHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHEETE 1390
H+ + +C CG++F L H H E
Sbjct: 922 THAGEK----------PYKCEECGKAFSWPSRLTEHKATHAGEE 955
Score = 133 bits (335), Expect = 1e-30
Identities = 130/620 (20%), Positives = 232/620 (37%), Gaps = 101/620 (16%)
Query: 821 HTCSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQ 879
+ C +CG +F ++ L+ H+ H Y+C C K F + L H H T +
Sbjct: 593 YKCEECGKAFNWSSNLMEHKRIHTGEKPYKCEECGKSFSTFSVLTKHKVIH-----TGEK 647
Query: 880 PFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAE 939
P+ C CG + + H++ H T + EE G A + +
Sbjct: 648 PYKCEECGKAYKWSSTLSYHKK-IH-----TVEKPYKCEECGKA-----------FNRSA 690
Query: 940 LLNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDA 999
+L + +R + + + C CG+T+ + +L H A + P G A
Sbjct: 691 ILIKHKR----IHTDEKPYKCEECGKTFSKVSTLTTH-----KAIHAGEKPYKCKECGKA 741
Query: 1000 MEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGK 1059
++++ GE + G +L + +P++C +CGK
Sbjct: 742 FSKFSILTKHKVIHT--GEKPYKCEECGKAYKWPSTLSYH---KKIHTGEKPYKCEECGK 796
Query: 1060 TYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHP-----RCKGSEPQVG 1112
+ L H IH TG+ + C C + + L+ + H + H +C+
Sbjct: 797 GFSMFSILTKHEVIH-TGEKPYKCEECGKAFSWLSVFSKHKKTHAGEKFYKCEACGKAYN 855
Query: 1113 PIPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKE--- 1169
+ G KP E G L E K+ E + +E
Sbjct: 856 TFSILTKHKVIHTG-------EKPYKCEECGKAFNWSSNLMEHKKIHTGETPYKCEECDK 908
Query: 1170 ------EVWEETTVKGEEIEPRLETAEKGCQTEA---------SSERPFSCEVCGRSYKH 1214
+ E E + E K + + E P+ CE CG+++
Sbjct: 909 AFSWPSSLTEHKATHAGEKPYKCEECGKAFSWPSRLTEHKATHAGEEPYKCEECGKAFNW 968
Query: 1215 AGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQ 1272
+ +L+ H++ H TG + C+ C K FS L H+ IH + ++C ECGKA++
Sbjct: 969 SSNLMEHKRIH-TGEKPYKCEECGKSFSTFSILTKHKVIHTGEKPYKCEECGKAYKWSST 1027
Query: 1273 LASHQRVH-------MERRGGGGT--------RKATREDRPFRCGQCGRTYRHAGSLLNH 1317
L+ H+++H E G G + ++ ++C +CG+ Y+ +L H
Sbjct: 1028 LSYHKKIHTVEKPYKCEECGKGFVMFSILAKHKVIHTGEKLYKCEECGKAYKWPSTLRYH 1087
Query: 1318 RRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPG 1375
++ H TG+ Y C C K +S L H+ +H+ + +C CG++F
Sbjct: 1088 KKIH-TGEKPYKCEECGKAFSTFSILTKHKVIHTGEK----------PYKCEECGKAFSW 1136
Query: 1376 RGSLERHLREHEETEREPAN 1395
+H + H P +
Sbjct: 1137 LSVFSKHKKIHTGVPNPPTH 1156
Score = 131 bits (330), Expect = 5e-30
Identities = 97/364 (26%), Positives = 157/364 (43%), Gaps = 58/364 (15%)
Query: 1050 RPFRCNQCGKTYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGS 1107
+P+RC +CGK + L H+ IH TG+ + C C + + A H H G
Sbjct: 227 KPYRCKECGKAFSKFSILTKHKVIH-TGEKSYKCEECGKAFNQSAILTKHKIIH---TGE 282
Query: 1108 EPQVGPIPEAAGSSELQVGPIPE----GGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEE 1163
+P E G + +V + KP E G ++V L + E+
Sbjct: 283 KPNK---CEECGKAFSKVSTLTTHKAIHAGEKPYKCKECGKAFSKVSTLITHKAIHAGEK 339
Query: 1164 VARVKE--EVWEETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINH 1221
+ KE + + + ++ T K T E+P+ CE CG++YK +L H
Sbjct: 340 PYKCKECGKAFSKFSIL---------TKHKVIHT---GEKPYKCEECGKAYKWPSTLSYH 387
Query: 1222 RQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRV 1279
++ H TG + C+ C KGFS L H IH + ++C ECGKAF L H+++
Sbjct: 388 KKIH-TGEKPYKCEECGKGFSMFSILTKHEVIHTGEKPYKCEECGKAFNWSSNLMEHKKI 446
Query: 1280 H-------MERRGGGGT--------RKATREDRPFRCGQCGRTYRHAGSLLNHRRSHETG 1324
H E G G + +K ++P++C +CG+ + + L+ H+R H TG
Sbjct: 447 HTGETPYKCEECGKGFSWSSTLSYHKKIHTVEKPYKCEECGKAFNQSAILIKHKRIH-TG 505
Query: 1325 Q--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERH 1382
+ Y C C KT+S L H+ +H+ + +C CG++F +L H
Sbjct: 506 EKPYKCEECGKTFSKVSTLTTHKAIHAGEK----------PYKCKECGKTFIKVSTLTTH 555
Query: 1383 LREH 1386
H
Sbjct: 556 KAIH 559
Score = 124 bits (311), Expect = 8e-28
Identities = 115/463 (24%), Positives = 181/463 (39%), Gaps = 75/463 (16%)
Query: 236 ERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPY 294
E YKC + GK + + +LT ++ +HT Y C C K FS L H +H + Y
Sbjct: 198 ENSYKCEEGGKAFNWSSTLTYYKSAHTGEKPYRCKECGKAFSKFSILTKHKVIHTGEKSY 257
Query: 295 HCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGS 354
C C + F L +H+ H GE+ + EE G + T L + + ++
Sbjct: 258 KCEECGKAFNQSAILTKHKIIHTGEKPN-KCEECGKAFSKVST-------LTTHKAIH-- 307
Query: 355 AELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQ-TGVYPCSLCSKQLFNA 413
+GE +P++C +CG+ + +LI H+ H Y C C K
Sbjct: 308 -----AGE---------KPYKCKECGKAFSKVSTLITHKAIHAGEKPYKCKECGKAFSKF 353
Query: 414 AALKNHVRAH--HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECG 471
+ L H H +P + E G+ P+ L + H E +PYKC ECG
Sbjct: 354 SILTKHKVIHTGEKPYK-CEECGKAYKWPSTLSYHKKIHTGE---------KPYKCEECG 403
Query: 472 RAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHCKAARRSADIGAEG- 528
+ + L H H TGE Y+C C + + L H ++H + +G
Sbjct: 404 KGFSMFSILTKHEVIH-TGEKPYKCEECGKAFNWSSNLMEHKKIHTGETPYKCEECGKGF 462
Query: 529 -----APSHLKVELPPDPVEAE--AAPHTDQDHVCKHEEEATDITPAADKTAAHICSICG 581
H K+ P + E + KH+ T P + C CG
Sbjct: 463 SWSSTLSYHKKIHTVEKPYKCEECGKAFNQSAILIKHKRIHTGEKP-------YKCEECG 515
Query: 582 LLFEDAESLERHGLTHGAGEKENSRTE--------TTMSPPRA-------FACRDCGKSY 626
F +L H H AGEK E +T++ +A + C++CGK++
Sbjct: 516 KTFSKVSTLTTHKAIH-AGEKPYKCKECGKTFIKVSTLTTHKAIHAGEKPYKCKECGKAF 574
Query: 627 RHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHS 667
L H+ H TG+ + C C K F+ + + H R H+
Sbjct: 575 SKFSILTKHKVIH-TGEKPYKCEECGKAFNWSSNLMEHKRIHT 616
Score = 102 bits (255), Expect = 3e-21
Identities = 75/277 (27%), Positives = 113/277 (40%), Gaps = 30/277 (10%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C +CGK + S +L+ H T + C C K F P + H H + + C +C
Sbjct: 875 CEECGKAFNWSSNLMEHKKIHTGETPYKCEECDKAFSWPSSLTEHKATHAGEKPYKCEEC 934
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEA-----------RDPKAGTGEDQVVLPGQG 1639
GKAF L H HA + P + EE + TGE G
Sbjct: 935 GKAFSWPSRLTEHKATHA---GEEPYKCEECGKAFNWSSNLMEHKRIHTGEKPYKCEECG 991
Query: 1640 KAQEAPS--------ETPRGPGESVERARGGQAVTSMAAEDK----ERPFRCTQCGRSYR 1687
K+ S T P + E + + ++++ K E+P++C +CG+ +
Sbjct: 992 KSFSTFSILTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEECGKGFV 1051
Query: 1688 HAGSLLNHQKAHT-TGLYPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAAR 1746
L H+ HT LY C C K +L+ H + HT K + C CGKAF T +
Sbjct: 1052 MFSILAKHKVIHTGEKLYKCEECGKAYKWPSTLRYHKKIHTGEKPYKCEECGKAFSTFSI 1111
Query: 1747 LEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQH 1783
L H +H E P+ C C + F F +H++ H
Sbjct: 1112 LTKHKVIHT-GEKPYKCEECGKAFSWLSVFSKHKKIH 1147
Score = 101 bits (252), Expect = 6e-21
Identities = 107/469 (22%), Positives = 177/469 (37%), Gaps = 75/469 (15%)
Query: 216 ESVVNFTGGQEPTQSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSHTLGIY-PCAICFKE 274
E V+ G + QS + + ++ + + + H+ HT + C +
Sbjct: 122 ECKVHKEGYNKLNQSLTTTQSKVFQRGKYANVFHKCSNSNRHKIRHTGKKHLQCKEYVRS 181
Query: 275 FSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTN 334
F L L H R++ + Y C + F L ++ +H GE+ R +E G +
Sbjct: 182 FCMLSHLSQHKRIYTRENSYKCEEGGKAFNWSSTLTYYKSAHTGEKPY-RCKECGKAFSK 240
Query: 335 G---------HTDESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRH 385
HT E S + N SA L T ++ +G +P +C +CG+ +
Sbjct: 241 FSILTKHKVIHTGEKSYKCEECGKAFNQSAIL-TKHKIIHTG---EKPNKCEECGKAFSK 296
Query: 386 AGSLINHRKSHQ-TGVYPCSLCSKQLFNAAALKNH--VRAHHRPRQGVGENGQPSVPPAP 442
+L H+ H Y C C K + L H + A +P + E G+ +
Sbjct: 297 VSTLTTHKAIHAGEKPYKCKECGKAFSKVSTLITHKAIHAGEKPYK-CKECGKAFSKFSI 355
Query: 443 LLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRK 500
L + H E +PYKC ECG+AY+ +L H+ H TGE Y+C C +
Sbjct: 356 LTKHKVIHTGE---------KPYKCEECGKAYKWPSTLSYHKKIH-TGEKPYKCEECGKG 405
Query: 501 YPNLMALRNHVRVHCKAARRSADIGAEGAPSHLKVELPPDPVEAEAAPHTDQDHVCKHEE 560
+ L H +H P E ++ +H++
Sbjct: 406 FSMFSILTKHEVIHTGE--------------------KPYKCEECGKAFNWSSNLMEHKK 445
Query: 561 EATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACR 620
T TP + C CG F + +L H H T+ P + C
Sbjct: 446 IHTGETP-------YKCEECGKGFSWSSTLSYHKKIH------------TVEKP--YKCE 484
Query: 621 DCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHS 667
+CGK++ S LI H++ H TG+ + C C K F ++ + H H+
Sbjct: 485 ECGKAFNQSAILIKHKRIH-TGEKPYKCEECGKTFSKVSTLTTHKAIHA 532
Score = 89.0 bits (219), Expect = 4e-17
Identities = 60/262 (22%), Positives = 103/262 (39%), Gaps = 16/262 (6%)
Query: 1530 HSSCSQCGKTYCQSGSLLNHNT--NKTDRHYCLLCSKEFLNPVATKSHSHNHIDAQTFAC 1587
H C + +++C L H + + + C K F + H + + C
Sbjct: 172 HLQCKEYVRSFCMLSHLSQHKRIYTRENSYKCEEGGKAFNWSSTLTYYKSAHTGEKPYRC 231
Query: 1588 PDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQ--GKAQEAP 1645
+CGKAF L H H S + +A + A + +++ G+ K +E
Sbjct: 232 KECGKAFSKFSILTKHKVIHTGEKSYKCEECGKAFNQSAILTKHKIIHTGEKPNKCEEC- 290
Query: 1646 SETPRGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-Y 1704
G++ + T A E+P++C +CG+++ +L+ H+ H Y
Sbjct: 291 -------GKAFSKV--STLTTHKAIHAGEKPYKCKECGKAFSKVSTLITHKAIHAGEKPY 341
Query: 1705 PCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCP 1764
C C K L H HT K + C CGKA++ + L H ++H E P+ C
Sbjct: 342 KCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGKAYKWPSTLSYHKKIHT-GEKPYKCE 400
Query: 1765 HCPRHFRRRISFVQHQQQHQEE 1786
C + F +H+ H E
Sbjct: 401 ECGKGFSMFSILTKHEVIHTGE 422
Score = 88.6 bits (218), Expect = 5e-17
Identities = 70/257 (27%), Positives = 101/257 (39%), Gaps = 31/257 (12%)
Query: 1533 CSQCGKTYCQSGSLLNHN-TNKTDRHY-CLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C +C K + SL H T+ ++ Y C C K F P H H + + C +C
Sbjct: 903 CEECDKAFSWPSSLTEHKATHAGEKPYKCEECGKAFSWPSRLTEHKATHAGEEPYKCEEC 962
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEA-----------RDPKAGTGEDQVVLPGQG 1639
GKAF L H + H + P + EE + TGE G
Sbjct: 963 GKAFNWSSNLMEHKRIHT---GEKPYKCEECGKSFSTFSILTKHKVIHTGEKPYKCEECG 1019
Query: 1640 KAQEAPS--------ETPRGPGESVERARGGQAVTSMAAEDK-----ERPFRCTQCGRSY 1686
KA + S T P + E +G + S+ A+ K E+ ++C +CG++Y
Sbjct: 1020 KAYKWSSTLSYHKKIHTVEKPYKCEECGKGF-VMFSILAKHKVIHTGEKLYKCEECGKAY 1078
Query: 1687 RHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAA 1745
+ +L H+K HT Y C C K L H HT K + C CGKAF +
Sbjct: 1079 KWPSTLRYHKKIHTGEKPYKCEECGKAFSTFSILTKHKVIHTGEKPYKCEECGKAFSWLS 1138
Query: 1746 RLEGHGRVHAPREGPFT 1762
H ++H P T
Sbjct: 1139 VFSKHKKIHTGVPNPPT 1155
Score = 70.1 bits (170), Expect = 2e-11
Identities = 45/177 (25%), Positives = 72/177 (40%), Gaps = 28/177 (15%)
Query: 1214 HAGSLINHRQSHQTG--HFGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRK 1271
H S N + TG H C+ + F L L H+RI+ ++C E GKAF
Sbjct: 155 HKCSNSNRHKIRHTGKKHLQCKEYVRSFCMLSHLSQHKRIYTRENSYKCEEGGKAFNWSS 214
Query: 1272 QLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCP 1329
L ++ H ++P+RC +CG+ + L H+ H TG+ Y C
Sbjct: 215 TLTYYKSAH-------------TGEKPYRCKECGKAFSKFSILTKHKVIH-TGEKSYKCE 260
Query: 1330 TCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREH 1386
C K ++ L H+ +H+ + +C CG++F +L H H
Sbjct: 261 ECGKAFNQSAILTKHKIIHTGEKPN----------KCEECGKAFSKVSTLTTHKAIH 307
Score = 46.6 bits (109), Expect = 2e-04
Identities = 31/111 (27%), Positives = 45/111 (40%), Gaps = 19/111 (17%)
Query: 8 LSCSDCQRHFPSLPELSRHRELLHPSPNQDSEE----------------ADSIPRPYRCQ 51
L C + R F L LS+H+ + + EE A + +PYRC+
Sbjct: 173 LQCKEYVRSFCMLSHLSQHKRIYTRENSYKCEEGGKAFNWSSTLTYYKSAHTGEKPYRCK 232
Query: 52 QCGRGYRHPGSLVNHRRTHETG--LFPCTTCGKDFSNPMALKSHMRTHAPE 100
+CG+ + L H+ H TG + C CGK F+ L H H E
Sbjct: 233 ECGKAFSKFSILTKHKVIH-TGEKSYKCEECGKAFNQSAILTKHKIIHTGE 282
>gi|153791350 replication initiator 1 isoform 1 [Homo sapiens]
Length = 567
Score = 184 bits (467), Expect = 7e-46
Identities = 168/636 (26%), Positives = 253/636 (39%), Gaps = 149/636 (23%)
Query: 789 TGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHT----------CSDCGHSFPHATGLLS 838
T V + A G+ + +H GW A HT C +CG F HA L
Sbjct: 43 TSVAQSGAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLAL 102
Query: 839 HRPCH----PPGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRA 894
HR H P + C LC + F AL H + H + + +P C C F R
Sbjct: 103 HRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAH----SAAKRPIACPKCERRFWRRK 158
Query: 895 GYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSA 954
R H R+ H + EA P
Sbjct: 159 QLRAHLRRCHPPA---------------PEARP--------------------------- 176
Query: 955 GYGHICGCCGQTY---DDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDI 1011
ICG CG+++ D L + +R H +++ A KA P A+
Sbjct: 177 ---FICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKALGPRPRGRPAV----------- 222
Query: 1012 VNSVSGEGGDAKSQEGAGTPLGDSLCIQG--------GESLLEAQPRPFRCNQCGKTYRH 1063
+ GGDA + P + C + + RP +C +CGK + +
Sbjct: 223 --TAPRPGGDAVDR-----PFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTN 275
Query: 1064 GGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAAGSS 1121
L +HR+IH TG+ + C C R + + +H + H R +GS Q P P GS
Sbjct: 276 KPYLTSHRRIH-TGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGS-AQAAPGP---GSP 330
Query: 1122 ELQVGP---IPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEP----LEEVARVKEEVWEE 1174
+L GP E P A+E P A E Q+ ++ P ++ R
Sbjct: 331 QLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGR-------- 382
Query: 1175 TTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH-FGCQ 1233
RLE + Q + + ERPF+C CG+++ L+ H + H F C+
Sbjct: 383 --------SFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACE 434
Query: 1234 ACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKAT 1293
C + FS L HRR HA R F C +CGKAFR + LA+H+R+H
Sbjct: 435 ECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIH------------- 481
Query: 1294 REDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSEN 1351
++P+ C CG+ + +L++HRR H TG+ Y+CP C +++S + L H++ H
Sbjct: 482 TGEKPYVCPDCGKAFSQKSNLVSHRRIH-TGERPYACPDCDRSFSQKSNLITHRKSH--- 537
Query: 1352 RRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHE 1387
R A CA+CG++F L H ++H+
Sbjct: 538 -------IRDGAFCCAICGQTFDDEERLLAHQKKHD 566
Score = 145 bits (366), Expect = 4e-34
Identities = 134/533 (25%), Positives = 209/533 (39%), Gaps = 107/533 (20%)
Query: 1197 ASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNH-RRIHA 1253
A+ + F+C +CG+S++ +L+ H ++H C C + F L+ H RR H
Sbjct: 110 ATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAHLRRCHP 169
Query: 1254 ---DPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATRE--------------- 1295
+ R F C CG++F QL +H+RVH+ KA
Sbjct: 170 PAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKALGPRPRGRPAVTAPRPGG 229
Query: 1296 ---DRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSE 1350
DRPF+C CG+ +RH +L+ HRR H TG+ + CP C K ++N+ L H+R+H+
Sbjct: 230 DAVDRPFQCACCGKRFRHKPNLIAHRRVH-TGERPHQCPECGKRFTNKPYLTSHRRIHTG 288
Query: 1351 NRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASEANL 1410
+ C CGR F + +L H + H+ +E G S
Sbjct: 289 EK----------PYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPG-----PGSPQLP 333
Query: 1411 TGSQGLETQLGGAEPVPHLEDGVP-RPGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGG 1469
G Q + A P+ ++ P P E Q PI EAP P + G
Sbjct: 334 AGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPI-----EAP-PSLYSCDDCG------ 381
Query: 1470 GLGNHSGGWVPQFLTRSEEPEDSVHRSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGS 1529
+ +FL R+ + + + R P +C N +H+ + S++ G
Sbjct: 382 -----RSFRLERFL-RAHQRQHTGER-PFTCAECGKNFGKKTHLVA------HSRVHSGE 428
Query: 1530 HS-SCSQCGKTYCQSGSLLNHNTNKT-DRHY-CLLCSKEFLNPVATKSHSHNHIDAQTFA 1586
+C +CG+ + Q L H + DR + C C K F + +H H + +
Sbjct: 429 RPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYV 488
Query: 1587 CPDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPS 1646
CPDCGKAF L SH + H TGE P ++ S
Sbjct: 489 CPDCGKAFSQKSNLVSHRRIH--------------------TGERPYACPDCDRSFSQKS 528
Query: 1647 ETPRGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAH 1699
+T + ++ F C CG+++ LL HQK H
Sbjct: 529 ----------------NLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 565
Score = 145 bits (365), Expect = 5e-34
Identities = 158/622 (25%), Positives = 215/622 (34%), Gaps = 149/622 (23%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C+ C+RHFP L H +P P C +CGR +RH L HR+
Sbjct: 59 CAHCRRHFPGWVALWLHTRRCQAR----------LPLP--CPECGRRFRHAPFLALHRQV 106
Query: 70 HETGL----FPCTTCGKDFSNPMALKSHMRTHAPEGR---------------------RR 104
H F C CG+ F +AL H+R H+ R RR
Sbjct: 107 HAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAHLRR 166
Query: 105 HRPPRPKEATPHLQGETVSTDSWGQRLGSSEGWENQTKHTEETPDCESVPDPRAASGTWE 164
PP P EA P + G S+ Q W+
Sbjct: 167 CHPPAP-EARPFICGNCGR--SFAQ---------------------------------WD 190
Query: 165 DLPTRQREGLASHPGPEDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGG 224
L +R +A E A GP A P P +
Sbjct: 191 QLVAHKRVHVAEAL-EEAAAKALGPRPRGRPAVTAPRPGGDAV----------------- 232
Query: 225 QEPTQSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSHTLGIYP--CAICFKEFSNLMALK 282
+R ++C+ CGK ++H +L HR+ HT G P C C K F+N L
Sbjct: 233 -----------DRPFQCACCGKRFRHKPNLIAHRRVHT-GERPHQCPECGKRFTNKPYLT 280
Query: 283 NHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHE-GERQEPRWEEKGMPTTNGHTDESS 341
+H R+H +PY C C R FR LL H + H+ E G P ES+
Sbjct: 281 SHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLPAGPQESA 340
Query: 342 QDQLPSAQMLNGSAELSTSGELEDSGLEEYRP--FRCGDCGRTYRHAGSLINHRKSHQTG 399
+ P+ + + E P + C DCGR++R L H++ H TG
Sbjct: 341 AEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQH-TG 399
Query: 400 VYP--CSLCSKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPT 457
P C+ C K L H R H R E L A H+ + P
Sbjct: 400 ERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAA---HRRDHAP- 455
Query: 458 TTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHC 515
RP+ C +CG+A+RH+ L HR H TGE Y C C + + L +H R+H
Sbjct: 456 ----DRPFVCPDCGKAFRHKPYLAAHRRIH-TGEKPYVCPDCGKAFSQKSNLVSHRRIHT 510
Query: 516 KAARRSADIGAEGAPSHLKVELPPDPVEAEAAPHTDQDHVCKHEEEATDITPAADKTAAH 575
E P A P D D + + + A
Sbjct: 511 G-------------------ERP------YACP--DCDRSFSQKSNLITHRKSHIRDGAF 543
Query: 576 ICSICGLLFEDAESLERHGLTH 597
C+ICG F+D E L H H
Sbjct: 544 CCAICGQTFDDEERLLAHQKKH 565
Score = 143 bits (360), Expect = 2e-33
Identities = 146/566 (25%), Positives = 210/566 (37%), Gaps = 97/566 (17%)
Query: 1202 PFSCEVCGRSYKHAGSLINHRQSHQTGH----FGCQACSKGFSNLMSLKNHRRIHADPRR 1257
P C CGR ++HA L HRQ H F C C + F ++L H R H+ +R
Sbjct: 84 PLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKR 143
Query: 1258 -FRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLN 1316
C +C + F RKQL +H R E RPF CG CGR++ L+
Sbjct: 144 PIACPKCERRFWRRKQLRAHLR---------RCHPPAPEARPFICGNCGRSFAQWDQLVA 194
Query: 1317 HRRSHETGQYSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGR 1376
H+R H + + + + R + R G + +CA CG+ F +
Sbjct: 195 HKRVHVA-----EALEEAAAKALGPRPRGR-PAVTAPRPGGDAVDRPFQCACCGKRFRHK 248
Query: 1377 GSLERHLREH--EETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVP 1434
+L H R H E + P G+ ++ LT + + T G +P P E G
Sbjct: 249 PNLIAHRRVHTGERPHQCPECGK-----RFTNKPYLTSHRRIHT---GEKPYPCKECGRR 300
Query: 1435 ---RPGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPED 1491
+P S S I S G A P G +G PQ + EP
Sbjct: 301 FRHKPNLLSHSKIHKRSE----------GSAQAAPGPGSPQLPAG---PQ--ESAAEPTP 345
Query: 1492 SVHRSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHSSCSQCGKTYCQSGSLLNHNT 1551
+V P A + P D + P S SC CG+++ L H
Sbjct: 346 AVPLKP--AQEPPPGAPPEHPQDPIE--------APPSLYSCDDCGRSFRLERFLRAHQR 395
Query: 1552 NKTDRH--YCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHAR 1609
T C C K F +HS H + FAC +CG+ F SHL AH R
Sbjct: 396 QHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQ----GSHLAAHRR 451
Query: 1610 GHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVERARGGQAVTSMA 1669
H+ + V P GKA P + R
Sbjct: 452 DHAP----------------DRPFVCPDCGKAFR------HKPYLAAHRR---------- 479
Query: 1670 AEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTD 1728
E+P+ C CG+++ +L++H++ HT Y C C + +L H ++H
Sbjct: 480 IHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIR 539
Query: 1729 PKRHCCSICGKAFRTAARLEGHGRVH 1754
CC+ICG+ F RL H + H
Sbjct: 540 DGAFCCAICGQTFDDEERLLAHQKKH 565
Score = 132 bits (333), Expect = 2e-30
Identities = 130/483 (26%), Positives = 184/483 (38%), Gaps = 109/483 (22%)
Query: 241 CSQCGKTYKHAGSLTNHRQSHTLGI----YPCAICFKEFSNLMALKNHSRLH-AQYRPYH 295
C +CG+ ++HA L HRQ H + C +C + F +AL H R H A RP
Sbjct: 87 CPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIA 146
Query: 296 CPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDES--SQDQLPSAQMLNG 353
CP C R F ++L H + E R P G+ S DQL + + ++
Sbjct: 147 CPKCERRFWRRKQLRAHLRRCHPPAPEAR------PFICGNCGRSFAQWDQLVAHKRVHV 200
Query: 354 SAELSTSGEL---------------EDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQT 398
+ L + G RPF+C CG+ +RH +LI HR+ H T
Sbjct: 201 AEALEEAAAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVH-T 259
Query: 399 GVYP--CSLCSKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDP 456
G P C C K+ N L +H R H GE
Sbjct: 260 GERPHQCPECGKRFTNKPYLTSHRRIH------TGE------------------------ 289
Query: 457 TTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGEYQCSLCPRK-YPNLMALRNHVRVHC 515
+PY C ECGR +RH+ +L++H H+ E P P L A
Sbjct: 290 ------KPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLPAGPQESAAEP 343
Query: 516 KAA--RRSADIGAEGAPSHLKVELPPDPVEAEAAPHTDQD---------HVCKHEEEATD 564
A + A GAP E P DP+EA + ++ D + H+ + T
Sbjct: 344 TPAVPLKPAQEPPPGAPP----EHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTG 399
Query: 565 ITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTETTM------------- 611
P C+ CG F L H H +GE+ + E
Sbjct: 400 ERPFT-------CAECGKNFGKKTHLVAHSRVH-SGERPFACEECGRRFSQGSHLAAHRR 451
Query: 612 --SPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHS 667
+P R F C DCGK++RH L HR+ H TG+ + C C K F + + +H R H+
Sbjct: 452 DHAPDRPFVCPDCGKAFRHKPYLAAHRRIH-TGEKPYVCPDCGKAFSQKSNLVSHRRIHT 510
Query: 668 RRR 670
R
Sbjct: 511 GER 513
Score = 116 bits (291), Expect = 2e-25
Identities = 74/262 (28%), Positives = 105/262 (40%), Gaps = 23/262 (8%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C+ CGK + +L+ H T H C C K F N SH H + + C +C
Sbjct: 238 CACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKEC 297
Query: 1591 GKAFESHQELASHLQAHARGHSQV-----PAQMEEARDPKAGTGEDQVVLPGQGKAQEAP 1645
G+ F L SH + H R P + P+ E +P + + P
Sbjct: 298 GRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEPPP 357
Query: 1646 SETPRGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLY 1704
P P + +E A S+ + C CGRS+R L HQ+ HT +
Sbjct: 358 GAPPEHPQDPIE------APPSL--------YSCDDCGRSFRLERFLRAHQRQHTGERPF 403
Query: 1705 PCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCP 1764
C+ C K L HSR H+ + C CG+ F + L H R HAP + PF CP
Sbjct: 404 TCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAP-DRPFVCP 462
Query: 1765 HCPRHFRRRISFVQHQQQHQEE 1786
C + FR + H++ H E
Sbjct: 463 DCGKAFRHKPYLAAHRRIHTGE 484
Score = 100 bits (248), Expect = 2e-20
Identities = 123/490 (25%), Positives = 175/490 (35%), Gaps = 83/490 (16%)
Query: 8 LSCSDCQRHFPSLPELSRHRELLHPSPNQDSEEA---------------------DSIPR 46
L C +C R F P L+ HR++ H + D A + R
Sbjct: 85 LPCPECGRRFRHAPFLALHRQV-HAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKR 143
Query: 47 PYRCQQCGRGYRHPGSLVNH-RRTH----ETGLFPCTTCGKDFSNPMALKSHMRTHAPEG 101
P C +C R + L H RR H E F C CG+ F+ L +H R H E
Sbjct: 144 PIACPKCERRFWRRKQLRAHLRRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEA 203
Query: 102 RRR-------HRP-PRPKEATPHLQGETVSTD----SWGQRLGSSEGW-ENQTKHTEETP 148
RP RP P G+ V G+R ++ HT E P
Sbjct: 204 LEEAAAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERP 263
Query: 149 DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDG------------ADGWGPSTNSARA 196
R + + R G +P E G + S SA+A
Sbjct: 264 HQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQA 323
Query: 197 PPLP----IPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEER--------RYKCSQC 244
P P +PA S E A V QEP P E + Y C C
Sbjct: 324 APGPGSPQLPAGPQESAAEPTPA---VPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDC 380
Query: 245 GKTYKHAGSLTNHRQSHTLGIYP--CAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRV 302
G++++ L H++ HT G P CA C K F L HSR+H+ RP+ C C R
Sbjct: 381 GRSFRLERFLRAHQRQHT-GERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRR 439
Query: 303 FRLPRELLEHQQSHEGER--------QEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGS 354
F L H++ H +R + R + HT E + +
Sbjct: 440 FSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQK 499
Query: 355 AELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSH-QTGVYPCSLCSKQLFNA 413
+ L + + RP+ C DC R++ +LI HRKSH + G + C++C + +
Sbjct: 500 SNLVSHRRIHTG----ERPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDE 555
Query: 414 AALKNHVRAH 423
L H + H
Sbjct: 556 ERLLAHQKKH 565
Score = 97.1 bits (240), Expect = 1e-19
Identities = 87/313 (27%), Positives = 121/313 (38%), Gaps = 55/313 (17%)
Query: 1533 CSQCGKTYCQSGSLLNHN----TNKTDRHY-CLLCSKEFLNPVATKSHSHNHIDAQT-FA 1586
C +CG+ + + L H D + C LC + F VA H H A+ A
Sbjct: 87 CPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIA 146
Query: 1587 CPDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGE------DQVVLPGQGK 1640
CP C + F ++L +HL+ R H P EAR G DQ+V +
Sbjct: 147 CPKCERRFWRRKQLRAHLR---RCHPPAP----EARPFICGNCGRSFAQWDQLVAHKRVH 199
Query: 1641 AQEAPSETPR---GPGESVERARGGQAVTSM--AAEDKERPFRCTQCGRSYRHAGSLLNH 1695
EA E GP R RG AVT+ + +RPF+C CG+ +RH +L+ H
Sbjct: 200 VAEALEEAAAKALGP-----RPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAH 254
Query: 1696 QKAHT-TGLYPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVH 1754
++ HT + C C K N L +H R HT K + C CG+ FR L H ++H
Sbjct: 255 RRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIH 314
Query: 1755 APREGPFTCPHCPRHFRRRISFVQHQQQHQEEWTVAGSGAPVAPVTGRGDLPLPPPPTPT 1814
EG G G+P P + P P P
Sbjct: 315 KRSEG-------------------------SAQAAPGPGSPQLPAGPQESAAEPTPAVPL 349
Query: 1815 TPLLDPSPQWPAD 1827
P +P P P +
Sbjct: 350 KPAQEPPPGAPPE 362
Score = 94.7 bits (234), Expect = 7e-19
Identities = 125/522 (23%), Positives = 182/522 (34%), Gaps = 74/522 (14%)
Query: 1297 RPFRCGQCGRTYRHAGSLLNH-RRSHETGQYSCPTCPKTYSNRMALKDHQRLHSENRRRR 1355
R RC C R + +L H RR CP C + + + L H+++H
Sbjct: 55 RAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVH------- 107
Query: 1356 AGRSRRTAVRCALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASEANLTGSQG 1415
A + C LCG+SF G +L HLR H +R A E +
Sbjct: 108 AAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIA--------CPKCERRFWRRKQ 159
Query: 1416 LETQLGGAEPV-----PHLEDGVPRPGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGGG 1470
L L P P + R + + E L A KA
Sbjct: 160 LRAHLRRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKA-------- 211
Query: 1471 LGNHSGGWVPQFLTRSEEPEDSVHRSPCHAGDCQLNGPTLSHMDSW-DNRDNSSQLQPGS 1529
LG G +T D+V R C G H + +R + +P
Sbjct: 212 LGPRPRG--RPAVTAPRPGGDAVDR----PFQCACCGKRFRHKPNLIAHRRVHTGERPHQ 265
Query: 1530 HSSCSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHS--HNHIDAQTF 1585
C GK + L +H T + C C + F + SHS H +
Sbjct: 266 CPEC---GKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQ 322
Query: 1586 ACPDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGT----GEDQVVLPGQ--- 1638
A P G S Q A ++ A VP ++ A++P G +D + P
Sbjct: 323 AAPGPG----SPQLPAGPQESAAEPTPAVP--LKPAQEPPPGAPPEHPQDPIEAPPSLYS 376
Query: 1639 ----GKA--------QEAPSETPRGPGESVERARGGQAVTSMAAEDK----ERPFRCTQC 1682
G++ T P E + T + A + ERPF C +C
Sbjct: 377 CDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEEC 436
Query: 1683 GRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAF 1741
GR + L H++ H + C C K + L H R HT K + C CGKAF
Sbjct: 437 GRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAF 496
Query: 1742 RTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQH 1783
+ L H R+H E P+ CP C R F ++ + + H++ H
Sbjct: 497 SQKSNLVSHRRIHT-GERPYACPDCDRSFSQKSNLITHRKSH 537
Score = 64.7 bits (156), Expect = 8e-10
Identities = 44/144 (30%), Positives = 62/144 (43%), Gaps = 9/144 (6%)
Query: 1676 PFRCTQCGRSYRHAGSLLNHQKAHTTGL----YPCSLCPKLLPNLLSLKNHSRTHTDPKR 1731
P C +CGR +RHA L H++ H + C LC + ++L H R H+ KR
Sbjct: 84 PLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKR 143
Query: 1732 H-CCSICGKAFRTAARLEGH-GRVH--APREGPFTCPHCPRHFRRRISFVQHQQQHQEEW 1787
C C + F +L H R H AP PF C +C R F + V H++ H E
Sbjct: 144 PIACPKCERRFWRRKQLRAHLRRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEA 203
Query: 1788 TVAGSGAPVAP-VTGRGDLPLPPP 1810
+ + P GR + P P
Sbjct: 204 LEEAAAKALGPRPRGRPAVTAPRP 227
Score = 57.8 bits (138), Expect = 1e-07
Identities = 42/145 (28%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Query: 1639 GKAQEAPSETPRGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKA 1698
G +QE+P + ES + G +V A+ R RC C R + +L H +
Sbjct: 22 GPSQESPQTLGK---ESRGLRQQGTSVAQSGAQAPGRAHRCAHCRRHFPGWVALWLHTRR 78
Query: 1699 HTTGL-YPCSLCPKLLPNLLSLKNHSRTH---TDPKRHCCSICGKAFRTAARLEGHGRVH 1754
L PC C + + L H + H T C +CG++FR L H R H
Sbjct: 79 CQARLPLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAH 138
Query: 1755 APREGPFTCPHCPRHFRRRISFVQH 1779
+ + P CP C R F RR H
Sbjct: 139 SAAKRPIACPKCERRFWRRKQLRAH 163
Score = 57.8 bits (138), Expect = 1e-07
Identities = 36/100 (36%), Positives = 45/100 (45%), Gaps = 14/100 (14%)
Query: 3 DTPPSL-SCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPG 61
+ PPSL SC DC R F R L Q + E RP+ C +CG+ +
Sbjct: 369 EAPPSLYSCDDCGRSF-------RLERFLRAHQRQHTGE-----RPFTCAECGKNFGKKT 416
Query: 62 SLVNHRRTHE-TGLFPCTTCGKDFSNPMALKSHMRTHAPE 100
LV H R H F C CG+ FS L +H R HAP+
Sbjct: 417 HLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPD 456
>gi|153792539 replication initiator 1 isoform 1 [Homo sapiens]
Length = 567
Score = 184 bits (467), Expect = 7e-46
Identities = 168/636 (26%), Positives = 253/636 (39%), Gaps = 149/636 (23%)
Query: 789 TGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHT----------CSDCGHSFPHATGLLS 838
T V + A G+ + +H GW A HT C +CG F HA L
Sbjct: 43 TSVAQSGAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLAL 102
Query: 839 HRPCH----PPGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRA 894
HR H P + C LC + F AL H + H + + +P C C F R
Sbjct: 103 HRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAH----SAAKRPIACPKCERRFWRRK 158
Query: 895 GYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSA 954
R H R+ H + EA P
Sbjct: 159 QLRAHLRRCHPPA---------------PEARP--------------------------- 176
Query: 955 GYGHICGCCGQTY---DDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDI 1011
ICG CG+++ D L + +R H +++ A KA P A+
Sbjct: 177 ---FICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKALGPRPRGRPAV----------- 222
Query: 1012 VNSVSGEGGDAKSQEGAGTPLGDSLCIQG--------GESLLEAQPRPFRCNQCGKTYRH 1063
+ GGDA + P + C + + RP +C +CGK + +
Sbjct: 223 --TAPRPGGDAVDR-----PFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTN 275
Query: 1064 GGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAAGSS 1121
L +HR+IH TG+ + C C R + + +H + H R +GS Q P P GS
Sbjct: 276 KPYLTSHRRIH-TGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGS-AQAAPGP---GSP 330
Query: 1122 ELQVGP---IPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEP----LEEVARVKEEVWEE 1174
+L GP E P A+E P A E Q+ ++ P ++ R
Sbjct: 331 QLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGR-------- 382
Query: 1175 TTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH-FGCQ 1233
RLE + Q + + ERPF+C CG+++ L+ H + H F C+
Sbjct: 383 --------SFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACE 434
Query: 1234 ACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKAT 1293
C + FS L HRR HA R F C +CGKAFR + LA+H+R+H
Sbjct: 435 ECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIH------------- 481
Query: 1294 REDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSEN 1351
++P+ C CG+ + +L++HRR H TG+ Y+CP C +++S + L H++ H
Sbjct: 482 TGEKPYVCPDCGKAFSQKSNLVSHRRIH-TGERPYACPDCDRSFSQKSNLITHRKSH--- 537
Query: 1352 RRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHE 1387
R A CA+CG++F L H ++H+
Sbjct: 538 -------IRDGAFCCAICGQTFDDEERLLAHQKKHD 566
Score = 145 bits (366), Expect = 4e-34
Identities = 134/533 (25%), Positives = 209/533 (39%), Gaps = 107/533 (20%)
Query: 1197 ASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNH-RRIHA 1253
A+ + F+C +CG+S++ +L+ H ++H C C + F L+ H RR H
Sbjct: 110 ATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAHLRRCHP 169
Query: 1254 ---DPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATRE--------------- 1295
+ R F C CG++F QL +H+RVH+ KA
Sbjct: 170 PAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKALGPRPRGRPAVTAPRPGG 229
Query: 1296 ---DRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSE 1350
DRPF+C CG+ +RH +L+ HRR H TG+ + CP C K ++N+ L H+R+H+
Sbjct: 230 DAVDRPFQCACCGKRFRHKPNLIAHRRVH-TGERPHQCPECGKRFTNKPYLTSHRRIHTG 288
Query: 1351 NRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASEANL 1410
+ C CGR F + +L H + H+ +E G S
Sbjct: 289 EK----------PYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPG-----PGSPQLP 333
Query: 1411 TGSQGLETQLGGAEPVPHLEDGVP-RPGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGG 1469
G Q + A P+ ++ P P E Q PI EAP P + G
Sbjct: 334 AGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPI-----EAP-PSLYSCDDCG------ 381
Query: 1470 GLGNHSGGWVPQFLTRSEEPEDSVHRSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGS 1529
+ +FL R+ + + + R P +C N +H+ + S++ G
Sbjct: 382 -----RSFRLERFL-RAHQRQHTGER-PFTCAECGKNFGKKTHLVA------HSRVHSGE 428
Query: 1530 HS-SCSQCGKTYCQSGSLLNHNTNKT-DRHY-CLLCSKEFLNPVATKSHSHNHIDAQTFA 1586
+C +CG+ + Q L H + DR + C C K F + +H H + +
Sbjct: 429 RPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYV 488
Query: 1587 CPDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPS 1646
CPDCGKAF L SH + H TGE P ++ S
Sbjct: 489 CPDCGKAFSQKSNLVSHRRIH--------------------TGERPYACPDCDRSFSQKS 528
Query: 1647 ETPRGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAH 1699
+T + ++ F C CG+++ LL HQK H
Sbjct: 529 ----------------NLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 565
Score = 145 bits (365), Expect = 5e-34
Identities = 158/622 (25%), Positives = 215/622 (34%), Gaps = 149/622 (23%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C+ C+RHFP L H +P P C +CGR +RH L HR+
Sbjct: 59 CAHCRRHFPGWVALWLHTRRCQAR----------LPLP--CPECGRRFRHAPFLALHRQV 106
Query: 70 HETGL----FPCTTCGKDFSNPMALKSHMRTHAPEGR---------------------RR 104
H F C CG+ F +AL H+R H+ R RR
Sbjct: 107 HAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAHLRR 166
Query: 105 HRPPRPKEATPHLQGETVSTDSWGQRLGSSEGWENQTKHTEETPDCESVPDPRAASGTWE 164
PP P EA P + G S+ Q W+
Sbjct: 167 CHPPAP-EARPFICGNCGR--SFAQ---------------------------------WD 190
Query: 165 DLPTRQREGLASHPGPEDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGG 224
L +R +A E A GP A P P +
Sbjct: 191 QLVAHKRVHVAEAL-EEAAAKALGPRPRGRPAVTAPRPGGDAV----------------- 232
Query: 225 QEPTQSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSHTLGIYP--CAICFKEFSNLMALK 282
+R ++C+ CGK ++H +L HR+ HT G P C C K F+N L
Sbjct: 233 -----------DRPFQCACCGKRFRHKPNLIAHRRVHT-GERPHQCPECGKRFTNKPYLT 280
Query: 283 NHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHE-GERQEPRWEEKGMPTTNGHTDESS 341
+H R+H +PY C C R FR LL H + H+ E G P ES+
Sbjct: 281 SHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLPAGPQESA 340
Query: 342 QDQLPSAQMLNGSAELSTSGELEDSGLEEYRP--FRCGDCGRTYRHAGSLINHRKSHQTG 399
+ P+ + + E P + C DCGR++R L H++ H TG
Sbjct: 341 AEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQH-TG 399
Query: 400 VYP--CSLCSKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPT 457
P C+ C K L H R H R E L A H+ + P
Sbjct: 400 ERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAA---HRRDHAP- 455
Query: 458 TTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHC 515
RP+ C +CG+A+RH+ L HR H TGE Y C C + + L +H R+H
Sbjct: 456 ----DRPFVCPDCGKAFRHKPYLAAHRRIH-TGEKPYVCPDCGKAFSQKSNLVSHRRIHT 510
Query: 516 KAARRSADIGAEGAPSHLKVELPPDPVEAEAAPHTDQDHVCKHEEEATDITPAADKTAAH 575
E P A P D D + + + A
Sbjct: 511 G-------------------ERP------YACP--DCDRSFSQKSNLITHRKSHIRDGAF 543
Query: 576 ICSICGLLFEDAESLERHGLTH 597
C+ICG F+D E L H H
Sbjct: 544 CCAICGQTFDDEERLLAHQKKH 565
Score = 143 bits (360), Expect = 2e-33
Identities = 146/566 (25%), Positives = 210/566 (37%), Gaps = 97/566 (17%)
Query: 1202 PFSCEVCGRSYKHAGSLINHRQSHQTGH----FGCQACSKGFSNLMSLKNHRRIHADPRR 1257
P C CGR ++HA L HRQ H F C C + F ++L H R H+ +R
Sbjct: 84 PLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKR 143
Query: 1258 -FRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLN 1316
C +C + F RKQL +H R E RPF CG CGR++ L+
Sbjct: 144 PIACPKCERRFWRRKQLRAHLR---------RCHPPAPEARPFICGNCGRSFAQWDQLVA 194
Query: 1317 HRRSHETGQYSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGR 1376
H+R H + + + + R + R G + +CA CG+ F +
Sbjct: 195 HKRVHVA-----EALEEAAAKALGPRPRGR-PAVTAPRPGGDAVDRPFQCACCGKRFRHK 248
Query: 1377 GSLERHLREH--EETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVP 1434
+L H R H E + P G+ ++ LT + + T G +P P E G
Sbjct: 249 PNLIAHRRVHTGERPHQCPECGK-----RFTNKPYLTSHRRIHT---GEKPYPCKECGRR 300
Query: 1435 ---RPGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPED 1491
+P S S I S G A P G +G PQ + EP
Sbjct: 301 FRHKPNLLSHSKIHKRSE----------GSAQAAPGPGSPQLPAG---PQ--ESAAEPTP 345
Query: 1492 SVHRSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHSSCSQCGKTYCQSGSLLNHNT 1551
+V P A + P D + P S SC CG+++ L H
Sbjct: 346 AVPLKP--AQEPPPGAPPEHPQDPIE--------APPSLYSCDDCGRSFRLERFLRAHQR 395
Query: 1552 NKTDRH--YCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHAR 1609
T C C K F +HS H + FAC +CG+ F SHL AH R
Sbjct: 396 QHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQ----GSHLAAHRR 451
Query: 1610 GHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVERARGGQAVTSMA 1669
H+ + V P GKA P + R
Sbjct: 452 DHAP----------------DRPFVCPDCGKAFR------HKPYLAAHRR---------- 479
Query: 1670 AEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTD 1728
E+P+ C CG+++ +L++H++ HT Y C C + +L H ++H
Sbjct: 480 IHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIR 539
Query: 1729 PKRHCCSICGKAFRTAARLEGHGRVH 1754
CC+ICG+ F RL H + H
Sbjct: 540 DGAFCCAICGQTFDDEERLLAHQKKH 565
Score = 132 bits (333), Expect = 2e-30
Identities = 130/483 (26%), Positives = 184/483 (38%), Gaps = 109/483 (22%)
Query: 241 CSQCGKTYKHAGSLTNHRQSHTLGI----YPCAICFKEFSNLMALKNHSRLH-AQYRPYH 295
C +CG+ ++HA L HRQ H + C +C + F +AL H R H A RP
Sbjct: 87 CPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIA 146
Query: 296 CPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDES--SQDQLPSAQMLNG 353
CP C R F ++L H + E R P G+ S DQL + + ++
Sbjct: 147 CPKCERRFWRRKQLRAHLRRCHPPAPEAR------PFICGNCGRSFAQWDQLVAHKRVHV 200
Query: 354 SAELSTSGEL---------------EDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQT 398
+ L + G RPF+C CG+ +RH +LI HR+ H T
Sbjct: 201 AEALEEAAAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVH-T 259
Query: 399 GVYP--CSLCSKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDP 456
G P C C K+ N L +H R H GE
Sbjct: 260 GERPHQCPECGKRFTNKPYLTSHRRIH------TGE------------------------ 289
Query: 457 TTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGEYQCSLCPRK-YPNLMALRNHVRVHC 515
+PY C ECGR +RH+ +L++H H+ E P P L A
Sbjct: 290 ------KPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLPAGPQESAAEP 343
Query: 516 KAA--RRSADIGAEGAPSHLKVELPPDPVEAEAAPHTDQD---------HVCKHEEEATD 564
A + A GAP E P DP+EA + ++ D + H+ + T
Sbjct: 344 TPAVPLKPAQEPPPGAPP----EHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTG 399
Query: 565 ITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTETTM------------- 611
P C+ CG F L H H +GE+ + E
Sbjct: 400 ERPFT-------CAECGKNFGKKTHLVAHSRVH-SGERPFACEECGRRFSQGSHLAAHRR 451
Query: 612 --SPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHS 667
+P R F C DCGK++RH L HR+ H TG+ + C C K F + + +H R H+
Sbjct: 452 DHAPDRPFVCPDCGKAFRHKPYLAAHRRIH-TGEKPYVCPDCGKAFSQKSNLVSHRRIHT 510
Query: 668 RRR 670
R
Sbjct: 511 GER 513
Score = 116 bits (291), Expect = 2e-25
Identities = 74/262 (28%), Positives = 105/262 (40%), Gaps = 23/262 (8%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C+ CGK + +L+ H T H C C K F N SH H + + C +C
Sbjct: 238 CACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKEC 297
Query: 1591 GKAFESHQELASHLQAHARGHSQV-----PAQMEEARDPKAGTGEDQVVLPGQGKAQEAP 1645
G+ F L SH + H R P + P+ E +P + + P
Sbjct: 298 GRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEPPP 357
Query: 1646 SETPRGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLY 1704
P P + +E A S+ + C CGRS+R L HQ+ HT +
Sbjct: 358 GAPPEHPQDPIE------APPSL--------YSCDDCGRSFRLERFLRAHQRQHTGERPF 403
Query: 1705 PCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCP 1764
C+ C K L HSR H+ + C CG+ F + L H R HAP + PF CP
Sbjct: 404 TCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAP-DRPFVCP 462
Query: 1765 HCPRHFRRRISFVQHQQQHQEE 1786
C + FR + H++ H E
Sbjct: 463 DCGKAFRHKPYLAAHRRIHTGE 484
Score = 100 bits (248), Expect = 2e-20
Identities = 123/490 (25%), Positives = 175/490 (35%), Gaps = 83/490 (16%)
Query: 8 LSCSDCQRHFPSLPELSRHRELLHPSPNQDSEEA---------------------DSIPR 46
L C +C R F P L+ HR++ H + D A + R
Sbjct: 85 LPCPECGRRFRHAPFLALHRQV-HAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKR 143
Query: 47 PYRCQQCGRGYRHPGSLVNH-RRTH----ETGLFPCTTCGKDFSNPMALKSHMRTHAPEG 101
P C +C R + L H RR H E F C CG+ F+ L +H R H E
Sbjct: 144 PIACPKCERRFWRRKQLRAHLRRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEA 203
Query: 102 RRR-------HRP-PRPKEATPHLQGETVSTD----SWGQRLGSSEGW-ENQTKHTEETP 148
RP RP P G+ V G+R ++ HT E P
Sbjct: 204 LEEAAAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERP 263
Query: 149 DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDG------------ADGWGPSTNSARA 196
R + + R G +P E G + S SA+A
Sbjct: 264 HQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQA 323
Query: 197 PPLP----IPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEER--------RYKCSQC 244
P P +PA S E A V QEP P E + Y C C
Sbjct: 324 APGPGSPQLPAGPQESAAEPTPA---VPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDC 380
Query: 245 GKTYKHAGSLTNHRQSHTLGIYP--CAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRV 302
G++++ L H++ HT G P CA C K F L HSR+H+ RP+ C C R
Sbjct: 381 GRSFRLERFLRAHQRQHT-GERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRR 439
Query: 303 FRLPRELLEHQQSHEGER--------QEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGS 354
F L H++ H +R + R + HT E + +
Sbjct: 440 FSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQK 499
Query: 355 AELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSH-QTGVYPCSLCSKQLFNA 413
+ L + + RP+ C DC R++ +LI HRKSH + G + C++C + +
Sbjct: 500 SNLVSHRRIHTG----ERPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDE 555
Query: 414 AALKNHVRAH 423
L H + H
Sbjct: 556 ERLLAHQKKH 565
Score = 97.1 bits (240), Expect = 1e-19
Identities = 87/313 (27%), Positives = 121/313 (38%), Gaps = 55/313 (17%)
Query: 1533 CSQCGKTYCQSGSLLNHN----TNKTDRHY-CLLCSKEFLNPVATKSHSHNHIDAQT-FA 1586
C +CG+ + + L H D + C LC + F VA H H A+ A
Sbjct: 87 CPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIA 146
Query: 1587 CPDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGE------DQVVLPGQGK 1640
CP C + F ++L +HL+ R H P EAR G DQ+V +
Sbjct: 147 CPKCERRFWRRKQLRAHLR---RCHPPAP----EARPFICGNCGRSFAQWDQLVAHKRVH 199
Query: 1641 AQEAPSETPR---GPGESVERARGGQAVTSM--AAEDKERPFRCTQCGRSYRHAGSLLNH 1695
EA E GP R RG AVT+ + +RPF+C CG+ +RH +L+ H
Sbjct: 200 VAEALEEAAAKALGP-----RPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAH 254
Query: 1696 QKAHT-TGLYPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVH 1754
++ HT + C C K N L +H R HT K + C CG+ FR L H ++H
Sbjct: 255 RRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIH 314
Query: 1755 APREGPFTCPHCPRHFRRRISFVQHQQQHQEEWTVAGSGAPVAPVTGRGDLPLPPPPTPT 1814
EG G G+P P + P P P
Sbjct: 315 KRSEG-------------------------SAQAAPGPGSPQLPAGPQESAAEPTPAVPL 349
Query: 1815 TPLLDPSPQWPAD 1827
P +P P P +
Sbjct: 350 KPAQEPPPGAPPE 362
Score = 94.7 bits (234), Expect = 7e-19
Identities = 125/522 (23%), Positives = 182/522 (34%), Gaps = 74/522 (14%)
Query: 1297 RPFRCGQCGRTYRHAGSLLNH-RRSHETGQYSCPTCPKTYSNRMALKDHQRLHSENRRRR 1355
R RC C R + +L H RR CP C + + + L H+++H
Sbjct: 55 RAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVH------- 107
Query: 1356 AGRSRRTAVRCALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASEANLTGSQG 1415
A + C LCG+SF G +L HLR H +R A E +
Sbjct: 108 AAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIA--------CPKCERRFWRRKQ 159
Query: 1416 LETQLGGAEPV-----PHLEDGVPRPGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGGG 1470
L L P P + R + + E L A KA
Sbjct: 160 LRAHLRRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKA-------- 211
Query: 1471 LGNHSGGWVPQFLTRSEEPEDSVHRSPCHAGDCQLNGPTLSHMDSW-DNRDNSSQLQPGS 1529
LG G +T D+V R C G H + +R + +P
Sbjct: 212 LGPRPRG--RPAVTAPRPGGDAVDR----PFQCACCGKRFRHKPNLIAHRRVHTGERPHQ 265
Query: 1530 HSSCSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHS--HNHIDAQTF 1585
C GK + L +H T + C C + F + SHS H +
Sbjct: 266 CPEC---GKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQ 322
Query: 1586 ACPDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGT----GEDQVVLPGQ--- 1638
A P G S Q A ++ A VP ++ A++P G +D + P
Sbjct: 323 AAPGPG----SPQLPAGPQESAAEPTPAVP--LKPAQEPPPGAPPEHPQDPIEAPPSLYS 376
Query: 1639 ----GKA--------QEAPSETPRGPGESVERARGGQAVTSMAAEDK----ERPFRCTQC 1682
G++ T P E + T + A + ERPF C +C
Sbjct: 377 CDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEEC 436
Query: 1683 GRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAF 1741
GR + L H++ H + C C K + L H R HT K + C CGKAF
Sbjct: 437 GRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAF 496
Query: 1742 RTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQH 1783
+ L H R+H E P+ CP C R F ++ + + H++ H
Sbjct: 497 SQKSNLVSHRRIHT-GERPYACPDCDRSFSQKSNLITHRKSH 537
Score = 64.7 bits (156), Expect = 8e-10
Identities = 44/144 (30%), Positives = 62/144 (43%), Gaps = 9/144 (6%)
Query: 1676 PFRCTQCGRSYRHAGSLLNHQKAHTTGL----YPCSLCPKLLPNLLSLKNHSRTHTDPKR 1731
P C +CGR +RHA L H++ H + C LC + ++L H R H+ KR
Sbjct: 84 PLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKR 143
Query: 1732 H-CCSICGKAFRTAARLEGH-GRVH--APREGPFTCPHCPRHFRRRISFVQHQQQHQEEW 1787
C C + F +L H R H AP PF C +C R F + V H++ H E
Sbjct: 144 PIACPKCERRFWRRKQLRAHLRRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEA 203
Query: 1788 TVAGSGAPVAP-VTGRGDLPLPPP 1810
+ + P GR + P P
Sbjct: 204 LEEAAAKALGPRPRGRPAVTAPRP 227
Score = 57.8 bits (138), Expect = 1e-07
Identities = 42/145 (28%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Query: 1639 GKAQEAPSETPRGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKA 1698
G +QE+P + ES + G +V A+ R RC C R + +L H +
Sbjct: 22 GPSQESPQTLGK---ESRGLRQQGTSVAQSGAQAPGRAHRCAHCRRHFPGWVALWLHTRR 78
Query: 1699 HTTGL-YPCSLCPKLLPNLLSLKNHSRTH---TDPKRHCCSICGKAFRTAARLEGHGRVH 1754
L PC C + + L H + H T C +CG++FR L H R H
Sbjct: 79 CQARLPLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAH 138
Query: 1755 APREGPFTCPHCPRHFRRRISFVQH 1779
+ + P CP C R F RR H
Sbjct: 139 SAAKRPIACPKCERRFWRRKQLRAH 163
Score = 57.8 bits (138), Expect = 1e-07
Identities = 36/100 (36%), Positives = 45/100 (45%), Gaps = 14/100 (14%)
Query: 3 DTPPSL-SCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPG 61
+ PPSL SC DC R F R L Q + E RP+ C +CG+ +
Sbjct: 369 EAPPSLYSCDDCGRSF-------RLERFLRAHQRQHTGE-----RPFTCAECGKNFGKKT 416
Query: 62 SLVNHRRTHE-TGLFPCTTCGKDFSNPMALKSHMRTHAPE 100
LV H R H F C CG+ FS L +H R HAP+
Sbjct: 417 HLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPD 456
>gi|153792647 replication initiator 1 isoform 3 [Homo sapiens]
Length = 624
Score = 184 bits (467), Expect = 7e-46
Identities = 168/636 (26%), Positives = 253/636 (39%), Gaps = 149/636 (23%)
Query: 789 TGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHT----------CSDCGHSFPHATGLLS 838
T V + A G+ + +H GW A HT C +CG F HA L
Sbjct: 100 TSVAQSGAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLAL 159
Query: 839 HRPCH----PPGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRA 894
HR H P + C LC + F AL H + H + + +P C C F R
Sbjct: 160 HRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAH----SAAKRPIACPKCERRFWRRK 215
Query: 895 GYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSA 954
R H R+ H + EA P
Sbjct: 216 QLRAHLRRCHPPA---------------PEARP--------------------------- 233
Query: 955 GYGHICGCCGQTY---DDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDI 1011
ICG CG+++ D L + +R H +++ A KA P A+
Sbjct: 234 ---FICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKALGPRPRGRPAV----------- 279
Query: 1012 VNSVSGEGGDAKSQEGAGTPLGDSLCIQG--------GESLLEAQPRPFRCNQCGKTYRH 1063
+ GGDA + P + C + + RP +C +CGK + +
Sbjct: 280 --TAPRPGGDAVDR-----PFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTN 332
Query: 1064 GGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAAGSS 1121
L +HR+IH TG+ + C C R + + +H + H R +GS Q P P GS
Sbjct: 333 KPYLTSHRRIH-TGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGS-AQAAPGP---GSP 387
Query: 1122 ELQVGP---IPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEP----LEEVARVKEEVWEE 1174
+L GP E P A+E P A E Q+ ++ P ++ R
Sbjct: 388 QLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGR-------- 439
Query: 1175 TTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH-FGCQ 1233
RLE + Q + + ERPF+C CG+++ L+ H + H F C+
Sbjct: 440 --------SFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACE 491
Query: 1234 ACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKAT 1293
C + FS L HRR HA R F C +CGKAFR + LA+H+R+H
Sbjct: 492 ECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIH------------- 538
Query: 1294 REDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSEN 1351
++P+ C CG+ + +L++HRR H TG+ Y+CP C +++S + L H++ H
Sbjct: 539 TGEKPYVCPDCGKAFSQKSNLVSHRRIH-TGERPYACPDCDRSFSQKSNLITHRKSH--- 594
Query: 1352 RRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHE 1387
R A CA+CG++F L H ++H+
Sbjct: 595 -------IRDGAFCCAICGQTFDDEERLLAHQKKHD 623
Score = 145 bits (366), Expect = 4e-34
Identities = 134/533 (25%), Positives = 209/533 (39%), Gaps = 107/533 (20%)
Query: 1197 ASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNH-RRIHA 1253
A+ + F+C +CG+S++ +L+ H ++H C C + F L+ H RR H
Sbjct: 167 ATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAHLRRCHP 226
Query: 1254 ---DPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATRE--------------- 1295
+ R F C CG++F QL +H+RVH+ KA
Sbjct: 227 PAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKALGPRPRGRPAVTAPRPGG 286
Query: 1296 ---DRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSE 1350
DRPF+C CG+ +RH +L+ HRR H TG+ + CP C K ++N+ L H+R+H+
Sbjct: 287 DAVDRPFQCACCGKRFRHKPNLIAHRRVH-TGERPHQCPECGKRFTNKPYLTSHRRIHTG 345
Query: 1351 NRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASEANL 1410
+ C CGR F + +L H + H+ +E G S
Sbjct: 346 EK----------PYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPG-----PGSPQLP 390
Query: 1411 TGSQGLETQLGGAEPVPHLEDGVP-RPGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGG 1469
G Q + A P+ ++ P P E Q PI EAP P + G
Sbjct: 391 AGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPI-----EAP-PSLYSCDDCG------ 438
Query: 1470 GLGNHSGGWVPQFLTRSEEPEDSVHRSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGS 1529
+ +FL R+ + + + R P +C N +H+ + S++ G
Sbjct: 439 -----RSFRLERFL-RAHQRQHTGER-PFTCAECGKNFGKKTHLVA------HSRVHSGE 485
Query: 1530 HS-SCSQCGKTYCQSGSLLNHNTNKT-DRHY-CLLCSKEFLNPVATKSHSHNHIDAQTFA 1586
+C +CG+ + Q L H + DR + C C K F + +H H + +
Sbjct: 486 RPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYV 545
Query: 1587 CPDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPS 1646
CPDCGKAF L SH + H TGE P ++ S
Sbjct: 546 CPDCGKAFSQKSNLVSHRRIH--------------------TGERPYACPDCDRSFSQKS 585
Query: 1647 ETPRGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAH 1699
+T + ++ F C CG+++ LL HQK H
Sbjct: 586 ----------------NLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 622
Score = 145 bits (365), Expect = 5e-34
Identities = 158/622 (25%), Positives = 215/622 (34%), Gaps = 149/622 (23%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C+ C+RHFP L H +P P C +CGR +RH L HR+
Sbjct: 116 CAHCRRHFPGWVALWLHTRRCQAR----------LPLP--CPECGRRFRHAPFLALHRQV 163
Query: 70 HETGL----FPCTTCGKDFSNPMALKSHMRTHAPEGR---------------------RR 104
H F C CG+ F +AL H+R H+ R RR
Sbjct: 164 HAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAHLRR 223
Query: 105 HRPPRPKEATPHLQGETVSTDSWGQRLGSSEGWENQTKHTEETPDCESVPDPRAASGTWE 164
PP P EA P + G S+ Q W+
Sbjct: 224 CHPPAP-EARPFICGNCGR--SFAQ---------------------------------WD 247
Query: 165 DLPTRQREGLASHPGPEDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGG 224
L +R +A E A GP A P P +
Sbjct: 248 QLVAHKRVHVAEAL-EEAAAKALGPRPRGRPAVTAPRPGGDAV----------------- 289
Query: 225 QEPTQSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSHTLGIYP--CAICFKEFSNLMALK 282
+R ++C+ CGK ++H +L HR+ HT G P C C K F+N L
Sbjct: 290 -----------DRPFQCACCGKRFRHKPNLIAHRRVHT-GERPHQCPECGKRFTNKPYLT 337
Query: 283 NHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHE-GERQEPRWEEKGMPTTNGHTDESS 341
+H R+H +PY C C R FR LL H + H+ E G P ES+
Sbjct: 338 SHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLPAGPQESA 397
Query: 342 QDQLPSAQMLNGSAELSTSGELEDSGLEEYRP--FRCGDCGRTYRHAGSLINHRKSHQTG 399
+ P+ + + E P + C DCGR++R L H++ H TG
Sbjct: 398 AEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQH-TG 456
Query: 400 VYP--CSLCSKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPT 457
P C+ C K L H R H R E L A H+ + P
Sbjct: 457 ERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAA---HRRDHAP- 512
Query: 458 TTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHC 515
RP+ C +CG+A+RH+ L HR H TGE Y C C + + L +H R+H
Sbjct: 513 ----DRPFVCPDCGKAFRHKPYLAAHRRIH-TGEKPYVCPDCGKAFSQKSNLVSHRRIHT 567
Query: 516 KAARRSADIGAEGAPSHLKVELPPDPVEAEAAPHTDQDHVCKHEEEATDITPAADKTAAH 575
E P A P D D + + + A
Sbjct: 568 G-------------------ERP------YACP--DCDRSFSQKSNLITHRKSHIRDGAF 600
Query: 576 ICSICGLLFEDAESLERHGLTH 597
C+ICG F+D E L H H
Sbjct: 601 CCAICGQTFDDEERLLAHQKKH 622
Score = 143 bits (360), Expect = 2e-33
Identities = 146/566 (25%), Positives = 210/566 (37%), Gaps = 97/566 (17%)
Query: 1202 PFSCEVCGRSYKHAGSLINHRQSHQTGH----FGCQACSKGFSNLMSLKNHRRIHADPRR 1257
P C CGR ++HA L HRQ H F C C + F ++L H R H+ +R
Sbjct: 141 PLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKR 200
Query: 1258 -FRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLN 1316
C +C + F RKQL +H R E RPF CG CGR++ L+
Sbjct: 201 PIACPKCERRFWRRKQLRAHLR---------RCHPPAPEARPFICGNCGRSFAQWDQLVA 251
Query: 1317 HRRSHETGQYSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGR 1376
H+R H + + + + R + R G + +CA CG+ F +
Sbjct: 252 HKRVHVA-----EALEEAAAKALGPRPRGR-PAVTAPRPGGDAVDRPFQCACCGKRFRHK 305
Query: 1377 GSLERHLREH--EETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVP 1434
+L H R H E + P G+ ++ LT + + T G +P P E G
Sbjct: 306 PNLIAHRRVHTGERPHQCPECGK-----RFTNKPYLTSHRRIHT---GEKPYPCKECGRR 357
Query: 1435 ---RPGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPED 1491
+P S S I S G A P G +G PQ + EP
Sbjct: 358 FRHKPNLLSHSKIHKRSE----------GSAQAAPGPGSPQLPAG---PQ--ESAAEPTP 402
Query: 1492 SVHRSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHSSCSQCGKTYCQSGSLLNHNT 1551
+V P A + P D + P S SC CG+++ L H
Sbjct: 403 AVPLKP--AQEPPPGAPPEHPQDPIE--------APPSLYSCDDCGRSFRLERFLRAHQR 452
Query: 1552 NKTDRH--YCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHAR 1609
T C C K F +HS H + FAC +CG+ F SHL AH R
Sbjct: 453 QHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQ----GSHLAAHRR 508
Query: 1610 GHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVERARGGQAVTSMA 1669
H+ + V P GKA P + R
Sbjct: 509 DHAP----------------DRPFVCPDCGKAFR------HKPYLAAHRR---------- 536
Query: 1670 AEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTD 1728
E+P+ C CG+++ +L++H++ HT Y C C + +L H ++H
Sbjct: 537 IHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIR 596
Query: 1729 PKRHCCSICGKAFRTAARLEGHGRVH 1754
CC+ICG+ F RL H + H
Sbjct: 597 DGAFCCAICGQTFDDEERLLAHQKKH 622
Score = 132 bits (333), Expect = 2e-30
Identities = 130/483 (26%), Positives = 184/483 (38%), Gaps = 109/483 (22%)
Query: 241 CSQCGKTYKHAGSLTNHRQSHTLGI----YPCAICFKEFSNLMALKNHSRLH-AQYRPYH 295
C +CG+ ++HA L HRQ H + C +C + F +AL H R H A RP
Sbjct: 144 CPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIA 203
Query: 296 CPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDES--SQDQLPSAQMLNG 353
CP C R F ++L H + E R P G+ S DQL + + ++
Sbjct: 204 CPKCERRFWRRKQLRAHLRRCHPPAPEAR------PFICGNCGRSFAQWDQLVAHKRVHV 257
Query: 354 SAELSTSGEL---------------EDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQT 398
+ L + G RPF+C CG+ +RH +LI HR+ H T
Sbjct: 258 AEALEEAAAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVH-T 316
Query: 399 GVYP--CSLCSKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDP 456
G P C C K+ N L +H R H GE
Sbjct: 317 GERPHQCPECGKRFTNKPYLTSHRRIH------TGE------------------------ 346
Query: 457 TTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGEYQCSLCPRK-YPNLMALRNHVRVHC 515
+PY C ECGR +RH+ +L++H H+ E P P L A
Sbjct: 347 ------KPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLPAGPQESAAEP 400
Query: 516 KAA--RRSADIGAEGAPSHLKVELPPDPVEAEAAPHTDQD---------HVCKHEEEATD 564
A + A GAP E P DP+EA + ++ D + H+ + T
Sbjct: 401 TPAVPLKPAQEPPPGAPP----EHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTG 456
Query: 565 ITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTETTM------------- 611
P C+ CG F L H H +GE+ + E
Sbjct: 457 ERPFT-------CAECGKNFGKKTHLVAHSRVH-SGERPFACEECGRRFSQGSHLAAHRR 508
Query: 612 --SPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHS 667
+P R F C DCGK++RH L HR+ H TG+ + C C K F + + +H R H+
Sbjct: 509 DHAPDRPFVCPDCGKAFRHKPYLAAHRRIH-TGEKPYVCPDCGKAFSQKSNLVSHRRIHT 567
Query: 668 RRR 670
R
Sbjct: 568 GER 570
Score = 116 bits (291), Expect = 2e-25
Identities = 74/262 (28%), Positives = 105/262 (40%), Gaps = 23/262 (8%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C+ CGK + +L+ H T H C C K F N SH H + + C +C
Sbjct: 295 CACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKEC 354
Query: 1591 GKAFESHQELASHLQAHARGHSQV-----PAQMEEARDPKAGTGEDQVVLPGQGKAQEAP 1645
G+ F L SH + H R P + P+ E +P + + P
Sbjct: 355 GRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEPPP 414
Query: 1646 SETPRGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLY 1704
P P + +E A S+ + C CGRS+R L HQ+ HT +
Sbjct: 415 GAPPEHPQDPIE------APPSL--------YSCDDCGRSFRLERFLRAHQRQHTGERPF 460
Query: 1705 PCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCP 1764
C+ C K L HSR H+ + C CG+ F + L H R HAP + PF CP
Sbjct: 461 TCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAP-DRPFVCP 519
Query: 1765 HCPRHFRRRISFVQHQQQHQEE 1786
C + FR + H++ H E
Sbjct: 520 DCGKAFRHKPYLAAHRRIHTGE 541
Score = 100 bits (248), Expect = 2e-20
Identities = 123/490 (25%), Positives = 175/490 (35%), Gaps = 83/490 (16%)
Query: 8 LSCSDCQRHFPSLPELSRHRELLHPSPNQDSEEA---------------------DSIPR 46
L C +C R F P L+ HR++ H + D A + R
Sbjct: 142 LPCPECGRRFRHAPFLALHRQV-HAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKR 200
Query: 47 PYRCQQCGRGYRHPGSLVNH-RRTH----ETGLFPCTTCGKDFSNPMALKSHMRTHAPEG 101
P C +C R + L H RR H E F C CG+ F+ L +H R H E
Sbjct: 201 PIACPKCERRFWRRKQLRAHLRRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEA 260
Query: 102 RRR-------HRP-PRPKEATPHLQGETVSTD----SWGQRLGSSEGW-ENQTKHTEETP 148
RP RP P G+ V G+R ++ HT E P
Sbjct: 261 LEEAAAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERP 320
Query: 149 DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDG------------ADGWGPSTNSARA 196
R + + R G +P E G + S SA+A
Sbjct: 321 HQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQA 380
Query: 197 PPLP----IPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEER--------RYKCSQC 244
P P +PA S E A V QEP P E + Y C C
Sbjct: 381 APGPGSPQLPAGPQESAAEPTPA---VPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDC 437
Query: 245 GKTYKHAGSLTNHRQSHTLGIYP--CAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRV 302
G++++ L H++ HT G P CA C K F L HSR+H+ RP+ C C R
Sbjct: 438 GRSFRLERFLRAHQRQHT-GERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRR 496
Query: 303 FRLPRELLEHQQSHEGER--------QEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGS 354
F L H++ H +R + R + HT E + +
Sbjct: 497 FSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQK 556
Query: 355 AELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSH-QTGVYPCSLCSKQLFNA 413
+ L + + RP+ C DC R++ +LI HRKSH + G + C++C + +
Sbjct: 557 SNLVSHRRIHTG----ERPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDE 612
Query: 414 AALKNHVRAH 423
L H + H
Sbjct: 613 ERLLAHQKKH 622
Score = 97.1 bits (240), Expect = 1e-19
Identities = 87/313 (27%), Positives = 121/313 (38%), Gaps = 55/313 (17%)
Query: 1533 CSQCGKTYCQSGSLLNHN----TNKTDRHY-CLLCSKEFLNPVATKSHSHNHIDAQT-FA 1586
C +CG+ + + L H D + C LC + F VA H H A+ A
Sbjct: 144 CPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIA 203
Query: 1587 CPDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGE------DQVVLPGQGK 1640
CP C + F ++L +HL+ R H P EAR G DQ+V +
Sbjct: 204 CPKCERRFWRRKQLRAHLR---RCHPPAP----EARPFICGNCGRSFAQWDQLVAHKRVH 256
Query: 1641 AQEAPSETPR---GPGESVERARGGQAVTSM--AAEDKERPFRCTQCGRSYRHAGSLLNH 1695
EA E GP R RG AVT+ + +RPF+C CG+ +RH +L+ H
Sbjct: 257 VAEALEEAAAKALGP-----RPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAH 311
Query: 1696 QKAHT-TGLYPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVH 1754
++ HT + C C K N L +H R HT K + C CG+ FR L H ++H
Sbjct: 312 RRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIH 371
Query: 1755 APREGPFTCPHCPRHFRRRISFVQHQQQHQEEWTVAGSGAPVAPVTGRGDLPLPPPPTPT 1814
EG G G+P P + P P P
Sbjct: 372 KRSEG-------------------------SAQAAPGPGSPQLPAGPQESAAEPTPAVPL 406
Query: 1815 TPLLDPSPQWPAD 1827
P +P P P +
Sbjct: 407 KPAQEPPPGAPPE 419
Score = 94.7 bits (234), Expect = 7e-19
Identities = 125/522 (23%), Positives = 182/522 (34%), Gaps = 74/522 (14%)
Query: 1297 RPFRCGQCGRTYRHAGSLLNH-RRSHETGQYSCPTCPKTYSNRMALKDHQRLHSENRRRR 1355
R RC C R + +L H RR CP C + + + L H+++H
Sbjct: 112 RAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVH------- 164
Query: 1356 AGRSRRTAVRCALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASEANLTGSQG 1415
A + C LCG+SF G +L HLR H +R A E +
Sbjct: 165 AAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIA--------CPKCERRFWRRKQ 216
Query: 1416 LETQLGGAEPV-----PHLEDGVPRPGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGGG 1470
L L P P + R + + E L A KA
Sbjct: 217 LRAHLRRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKA-------- 268
Query: 1471 LGNHSGGWVPQFLTRSEEPEDSVHRSPCHAGDCQLNGPTLSHMDSW-DNRDNSSQLQPGS 1529
LG G +T D+V R C G H + +R + +P
Sbjct: 269 LGPRPRG--RPAVTAPRPGGDAVDR----PFQCACCGKRFRHKPNLIAHRRVHTGERPHQ 322
Query: 1530 HSSCSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHS--HNHIDAQTF 1585
C GK + L +H T + C C + F + SHS H +
Sbjct: 323 CPEC---GKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQ 379
Query: 1586 ACPDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGT----GEDQVVLPGQ--- 1638
A P G S Q A ++ A VP ++ A++P G +D + P
Sbjct: 380 AAPGPG----SPQLPAGPQESAAEPTPAVP--LKPAQEPPPGAPPEHPQDPIEAPPSLYS 433
Query: 1639 ----GKA--------QEAPSETPRGPGESVERARGGQAVTSMAAEDK----ERPFRCTQC 1682
G++ T P E + T + A + ERPF C +C
Sbjct: 434 CDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEEC 493
Query: 1683 GRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAF 1741
GR + L H++ H + C C K + L H R HT K + C CGKAF
Sbjct: 494 GRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAF 553
Query: 1742 RTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQH 1783
+ L H R+H E P+ CP C R F ++ + + H++ H
Sbjct: 554 SQKSNLVSHRRIHT-GERPYACPDCDRSFSQKSNLITHRKSH 594
Score = 64.7 bits (156), Expect = 8e-10
Identities = 44/144 (30%), Positives = 62/144 (43%), Gaps = 9/144 (6%)
Query: 1676 PFRCTQCGRSYRHAGSLLNHQKAHTTGL----YPCSLCPKLLPNLLSLKNHSRTHTDPKR 1731
P C +CGR +RHA L H++ H + C LC + ++L H R H+ KR
Sbjct: 141 PLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKR 200
Query: 1732 H-CCSICGKAFRTAARLEGH-GRVH--APREGPFTCPHCPRHFRRRISFVQHQQQHQEEW 1787
C C + F +L H R H AP PF C +C R F + V H++ H E
Sbjct: 201 PIACPKCERRFWRRKQLRAHLRRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEA 260
Query: 1788 TVAGSGAPVAP-VTGRGDLPLPPP 1810
+ + P GR + P P
Sbjct: 261 LEEAAAKALGPRPRGRPAVTAPRP 284
Score = 57.8 bits (138), Expect = 1e-07
Identities = 42/145 (28%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Query: 1639 GKAQEAPSETPRGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKA 1698
G +QE+P + ES + G +V A+ R RC C R + +L H +
Sbjct: 79 GPSQESPQTLGK---ESRGLRQQGTSVAQSGAQAPGRAHRCAHCRRHFPGWVALWLHTRR 135
Query: 1699 HTTGL-YPCSLCPKLLPNLLSLKNHSRTH---TDPKRHCCSICGKAFRTAARLEGHGRVH 1754
L PC C + + L H + H T C +CG++FR L H R H
Sbjct: 136 CQARLPLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAH 195
Query: 1755 APREGPFTCPHCPRHFRRRISFVQH 1779
+ + P CP C R F RR H
Sbjct: 196 SAAKRPIACPKCERRFWRRKQLRAH 220
Score = 57.8 bits (138), Expect = 1e-07
Identities = 36/100 (36%), Positives = 45/100 (45%), Gaps = 14/100 (14%)
Query: 3 DTPPSL-SCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPG 61
+ PPSL SC DC R F R L Q + E RP+ C +CG+ +
Sbjct: 426 EAPPSLYSCDDCGRSF-------RLERFLRAHQRQHTGE-----RPFTCAECGKNFGKKT 473
Query: 62 SLVNHRRTHE-TGLFPCTTCGKDFSNPMALKSHMRTHAPE 100
LV H R H F C CG+ FS L +H R HAP+
Sbjct: 474 HLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPD 513
>gi|153791994 replication initiator 1 isoform 1 [Homo sapiens]
Length = 567
Score = 184 bits (467), Expect = 7e-46
Identities = 168/636 (26%), Positives = 253/636 (39%), Gaps = 149/636 (23%)
Query: 789 TGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHT----------CSDCGHSFPHATGLLS 838
T V + A G+ + +H GW A HT C +CG F HA L
Sbjct: 43 TSVAQSGAQAPGRAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLAL 102
Query: 839 HRPCH----PPGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRA 894
HR H P + C LC + F AL H + H + + +P C C F R
Sbjct: 103 HRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAH----SAAKRPIACPKCERRFWRRK 158
Query: 895 GYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSA 954
R H R+ H + EA P
Sbjct: 159 QLRAHLRRCHPPA---------------PEARP--------------------------- 176
Query: 955 GYGHICGCCGQTY---DDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDI 1011
ICG CG+++ D L + +R H +++ A KA P A+
Sbjct: 177 ---FICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKALGPRPRGRPAV----------- 222
Query: 1012 VNSVSGEGGDAKSQEGAGTPLGDSLCIQG--------GESLLEAQPRPFRCNQCGKTYRH 1063
+ GGDA + P + C + + RP +C +CGK + +
Sbjct: 223 --TAPRPGGDAVDR-----PFQCACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTN 275
Query: 1064 GGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAAGSS 1121
L +HR+IH TG+ + C C R + + +H + H R +GS Q P P GS
Sbjct: 276 KPYLTSHRRIH-TGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGS-AQAAPGP---GSP 330
Query: 1122 ELQVGP---IPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEP----LEEVARVKEEVWEE 1174
+L GP E P A+E P A E Q+ ++ P ++ R
Sbjct: 331 QLPAGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGR-------- 382
Query: 1175 TTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH-FGCQ 1233
RLE + Q + + ERPF+C CG+++ L+ H + H F C+
Sbjct: 383 --------SFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACE 434
Query: 1234 ACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKAT 1293
C + FS L HRR HA R F C +CGKAFR + LA+H+R+H
Sbjct: 435 ECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIH------------- 481
Query: 1294 REDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSEN 1351
++P+ C CG+ + +L++HRR H TG+ Y+CP C +++S + L H++ H
Sbjct: 482 TGEKPYVCPDCGKAFSQKSNLVSHRRIH-TGERPYACPDCDRSFSQKSNLITHRKSH--- 537
Query: 1352 RRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHE 1387
R A CA+CG++F L H ++H+
Sbjct: 538 -------IRDGAFCCAICGQTFDDEERLLAHQKKHD 566
Score = 145 bits (366), Expect = 4e-34
Identities = 134/533 (25%), Positives = 209/533 (39%), Gaps = 107/533 (20%)
Query: 1197 ASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNH-RRIHA 1253
A+ + F+C +CG+S++ +L+ H ++H C C + F L+ H RR H
Sbjct: 110 ATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAHLRRCHP 169
Query: 1254 ---DPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATRE--------------- 1295
+ R F C CG++F QL +H+RVH+ KA
Sbjct: 170 PAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKALGPRPRGRPAVTAPRPGG 229
Query: 1296 ---DRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSE 1350
DRPF+C CG+ +RH +L+ HRR H TG+ + CP C K ++N+ L H+R+H+
Sbjct: 230 DAVDRPFQCACCGKRFRHKPNLIAHRRVH-TGERPHQCPECGKRFTNKPYLTSHRRIHTG 288
Query: 1351 NRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASEANL 1410
+ C CGR F + +L H + H+ +E G S
Sbjct: 289 EK----------PYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPG-----PGSPQLP 333
Query: 1411 TGSQGLETQLGGAEPVPHLEDGVP-RPGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGG 1469
G Q + A P+ ++ P P E Q PI EAP P + G
Sbjct: 334 AGPQESAAEPTPAVPLKPAQEPPPGAPPEHPQDPI-----EAP-PSLYSCDDCG------ 381
Query: 1470 GLGNHSGGWVPQFLTRSEEPEDSVHRSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGS 1529
+ +FL R+ + + + R P +C N +H+ + S++ G
Sbjct: 382 -----RSFRLERFL-RAHQRQHTGER-PFTCAECGKNFGKKTHLVA------HSRVHSGE 428
Query: 1530 HS-SCSQCGKTYCQSGSLLNHNTNKT-DRHY-CLLCSKEFLNPVATKSHSHNHIDAQTFA 1586
+C +CG+ + Q L H + DR + C C K F + +H H + +
Sbjct: 429 RPFACEECGRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYV 488
Query: 1587 CPDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPS 1646
CPDCGKAF L SH + H TGE P ++ S
Sbjct: 489 CPDCGKAFSQKSNLVSHRRIH--------------------TGERPYACPDCDRSFSQKS 528
Query: 1647 ETPRGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAH 1699
+T + ++ F C CG+++ LL HQK H
Sbjct: 529 ----------------NLITHRKSHIRDGAFCCAICGQTFDDEERLLAHQKKH 565
Score = 145 bits (365), Expect = 5e-34
Identities = 158/622 (25%), Positives = 215/622 (34%), Gaps = 149/622 (23%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C+ C+RHFP L H +P P C +CGR +RH L HR+
Sbjct: 59 CAHCRRHFPGWVALWLHTRRCQAR----------LPLP--CPECGRRFRHAPFLALHRQV 106
Query: 70 HETGL----FPCTTCGKDFSNPMALKSHMRTHAPEGR---------------------RR 104
H F C CG+ F +AL H+R H+ R RR
Sbjct: 107 HAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIACPKCERRFWRRKQLRAHLRR 166
Query: 105 HRPPRPKEATPHLQGETVSTDSWGQRLGSSEGWENQTKHTEETPDCESVPDPRAASGTWE 164
PP P EA P + G S+ Q W+
Sbjct: 167 CHPPAP-EARPFICGNCGR--SFAQ---------------------------------WD 190
Query: 165 DLPTRQREGLASHPGPEDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGG 224
L +R +A E A GP A P P +
Sbjct: 191 QLVAHKRVHVAEAL-EEAAAKALGPRPRGRPAVTAPRPGGDAV----------------- 232
Query: 225 QEPTQSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSHTLGIYP--CAICFKEFSNLMALK 282
+R ++C+ CGK ++H +L HR+ HT G P C C K F+N L
Sbjct: 233 -----------DRPFQCACCGKRFRHKPNLIAHRRVHT-GERPHQCPECGKRFTNKPYLT 280
Query: 283 NHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHE-GERQEPRWEEKGMPTTNGHTDESS 341
+H R+H +PY C C R FR LL H + H+ E G P ES+
Sbjct: 281 SHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLPAGPQESA 340
Query: 342 QDQLPSAQMLNGSAELSTSGELEDSGLEEYRP--FRCGDCGRTYRHAGSLINHRKSHQTG 399
+ P+ + + E P + C DCGR++R L H++ H TG
Sbjct: 341 AEPTPAVPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQH-TG 399
Query: 400 VYP--CSLCSKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPT 457
P C+ C K L H R H R E L A H+ + P
Sbjct: 400 ERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAA---HRRDHAP- 455
Query: 458 TTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHC 515
RP+ C +CG+A+RH+ L HR H TGE Y C C + + L +H R+H
Sbjct: 456 ----DRPFVCPDCGKAFRHKPYLAAHRRIH-TGEKPYVCPDCGKAFSQKSNLVSHRRIHT 510
Query: 516 KAARRSADIGAEGAPSHLKVELPPDPVEAEAAPHTDQDHVCKHEEEATDITPAADKTAAH 575
E P A P D D + + + A
Sbjct: 511 G-------------------ERP------YACP--DCDRSFSQKSNLITHRKSHIRDGAF 543
Query: 576 ICSICGLLFEDAESLERHGLTH 597
C+ICG F+D E L H H
Sbjct: 544 CCAICGQTFDDEERLLAHQKKH 565
Score = 143 bits (360), Expect = 2e-33
Identities = 146/566 (25%), Positives = 210/566 (37%), Gaps = 97/566 (17%)
Query: 1202 PFSCEVCGRSYKHAGSLINHRQSHQTGH----FGCQACSKGFSNLMSLKNHRRIHADPRR 1257
P C CGR ++HA L HRQ H F C C + F ++L H R H+ +R
Sbjct: 84 PLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKR 143
Query: 1258 -FRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLN 1316
C +C + F RKQL +H R E RPF CG CGR++ L+
Sbjct: 144 PIACPKCERRFWRRKQLRAHLR---------RCHPPAPEARPFICGNCGRSFAQWDQLVA 194
Query: 1317 HRRSHETGQYSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGR 1376
H+R H + + + + R + R G + +CA CG+ F +
Sbjct: 195 HKRVHVA-----EALEEAAAKALGPRPRGR-PAVTAPRPGGDAVDRPFQCACCGKRFRHK 248
Query: 1377 GSLERHLREH--EETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVP 1434
+L H R H E + P G+ ++ LT + + T G +P P E G
Sbjct: 249 PNLIAHRRVHTGERPHQCPECGK-----RFTNKPYLTSHRRIHT---GEKPYPCKECGRR 300
Query: 1435 ---RPGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPED 1491
+P S S I S G A P G +G PQ + EP
Sbjct: 301 FRHKPNLLSHSKIHKRSE----------GSAQAAPGPGSPQLPAG---PQ--ESAAEPTP 345
Query: 1492 SVHRSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHSSCSQCGKTYCQSGSLLNHNT 1551
+V P A + P D + P S SC CG+++ L H
Sbjct: 346 AVPLKP--AQEPPPGAPPEHPQDPIE--------APPSLYSCDDCGRSFRLERFLRAHQR 395
Query: 1552 NKTDRH--YCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHAR 1609
T C C K F +HS H + FAC +CG+ F SHL AH R
Sbjct: 396 QHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQ----GSHLAAHRR 451
Query: 1610 GHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVERARGGQAVTSMA 1669
H+ + V P GKA P + R
Sbjct: 452 DHAP----------------DRPFVCPDCGKAFR------HKPYLAAHRR---------- 479
Query: 1670 AEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTD 1728
E+P+ C CG+++ +L++H++ HT Y C C + +L H ++H
Sbjct: 480 IHTGEKPYVCPDCGKAFSQKSNLVSHRRIHTGERPYACPDCDRSFSQKSNLITHRKSHIR 539
Query: 1729 PKRHCCSICGKAFRTAARLEGHGRVH 1754
CC+ICG+ F RL H + H
Sbjct: 540 DGAFCCAICGQTFDDEERLLAHQKKH 565
Score = 132 bits (333), Expect = 2e-30
Identities = 130/483 (26%), Positives = 184/483 (38%), Gaps = 109/483 (22%)
Query: 241 CSQCGKTYKHAGSLTNHRQSHTLGI----YPCAICFKEFSNLMALKNHSRLH-AQYRPYH 295
C +CG+ ++HA L HRQ H + C +C + F +AL H R H A RP
Sbjct: 87 CPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIA 146
Query: 296 CPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDES--SQDQLPSAQMLNG 353
CP C R F ++L H + E R P G+ S DQL + + ++
Sbjct: 147 CPKCERRFWRRKQLRAHLRRCHPPAPEAR------PFICGNCGRSFAQWDQLVAHKRVHV 200
Query: 354 SAELSTSGEL---------------EDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQT 398
+ L + G RPF+C CG+ +RH +LI HR+ H T
Sbjct: 201 AEALEEAAAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVH-T 259
Query: 399 GVYP--CSLCSKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDP 456
G P C C K+ N L +H R H GE
Sbjct: 260 GERPHQCPECGKRFTNKPYLTSHRRIH------TGE------------------------ 289
Query: 457 TTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGEYQCSLCPRK-YPNLMALRNHVRVHC 515
+PY C ECGR +RH+ +L++H H+ E P P L A
Sbjct: 290 ------KPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLPAGPQESAAEP 343
Query: 516 KAA--RRSADIGAEGAPSHLKVELPPDPVEAEAAPHTDQD---------HVCKHEEEATD 564
A + A GAP E P DP+EA + ++ D + H+ + T
Sbjct: 344 TPAVPLKPAQEPPPGAPP----EHPQDPIEAPPSLYSCDDCGRSFRLERFLRAHQRQHTG 399
Query: 565 ITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTETTM------------- 611
P C+ CG F L H H +GE+ + E
Sbjct: 400 ERPFT-------CAECGKNFGKKTHLVAHSRVH-SGERPFACEECGRRFSQGSHLAAHRR 451
Query: 612 --SPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHS 667
+P R F C DCGK++RH L HR+ H TG+ + C C K F + + +H R H+
Sbjct: 452 DHAPDRPFVCPDCGKAFRHKPYLAAHRRIH-TGEKPYVCPDCGKAFSQKSNLVSHRRIHT 510
Query: 668 RRR 670
R
Sbjct: 511 GER 513
Score = 116 bits (291), Expect = 2e-25
Identities = 74/262 (28%), Positives = 105/262 (40%), Gaps = 23/262 (8%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C+ CGK + +L+ H T H C C K F N SH H + + C +C
Sbjct: 238 CACCGKRFRHKPNLIAHRRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKEC 297
Query: 1591 GKAFESHQELASHLQAHARGHSQV-----PAQMEEARDPKAGTGEDQVVLPGQGKAQEAP 1645
G+ F L SH + H R P + P+ E +P + + P
Sbjct: 298 GRRFRHKPNLLSHSKIHKRSEGSAQAAPGPGSPQLPAGPQESAAEPTPAVPLKPAQEPPP 357
Query: 1646 SETPRGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLY 1704
P P + +E A S+ + C CGRS+R L HQ+ HT +
Sbjct: 358 GAPPEHPQDPIE------APPSL--------YSCDDCGRSFRLERFLRAHQRQHTGERPF 403
Query: 1705 PCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCP 1764
C+ C K L HSR H+ + C CG+ F + L H R HAP + PF CP
Sbjct: 404 TCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAP-DRPFVCP 462
Query: 1765 HCPRHFRRRISFVQHQQQHQEE 1786
C + FR + H++ H E
Sbjct: 463 DCGKAFRHKPYLAAHRRIHTGE 484
Score = 100 bits (248), Expect = 2e-20
Identities = 123/490 (25%), Positives = 175/490 (35%), Gaps = 83/490 (16%)
Query: 8 LSCSDCQRHFPSLPELSRHRELLHPSPNQDSEEA---------------------DSIPR 46
L C +C R F P L+ HR++ H + D A + R
Sbjct: 85 LPCPECGRRFRHAPFLALHRQV-HAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKR 143
Query: 47 PYRCQQCGRGYRHPGSLVNH-RRTH----ETGLFPCTTCGKDFSNPMALKSHMRTHAPEG 101
P C +C R + L H RR H E F C CG+ F+ L +H R H E
Sbjct: 144 PIACPKCERRFWRRKQLRAHLRRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEA 203
Query: 102 RRR-------HRP-PRPKEATPHLQGETVSTD----SWGQRLGSSEGW-ENQTKHTEETP 148
RP RP P G+ V G+R ++ HT E P
Sbjct: 204 LEEAAAKALGPRPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAHRRVHTGERP 263
Query: 149 DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDG------------ADGWGPSTNSARA 196
R + + R G +P E G + S SA+A
Sbjct: 264 HQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQA 323
Query: 197 PPLP----IPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEER--------RYKCSQC 244
P P +PA S E A V QEP P E + Y C C
Sbjct: 324 APGPGSPQLPAGPQESAAEPTPA---VPLKPAQEPPPGAPPEHPQDPIEAPPSLYSCDDC 380
Query: 245 GKTYKHAGSLTNHRQSHTLGIYP--CAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRV 302
G++++ L H++ HT G P CA C K F L HSR+H+ RP+ C C R
Sbjct: 381 GRSFRLERFLRAHQRQHT-GERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEECGRR 439
Query: 303 FRLPRELLEHQQSHEGER--------QEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGS 354
F L H++ H +R + R + HT E + +
Sbjct: 440 FSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAFSQK 499
Query: 355 AELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSH-QTGVYPCSLCSKQLFNA 413
+ L + + RP+ C DC R++ +LI HRKSH + G + C++C + +
Sbjct: 500 SNLVSHRRIHTG----ERPYACPDCDRSFSQKSNLITHRKSHIRDGAFCCAICGQTFDDE 555
Query: 414 AALKNHVRAH 423
L H + H
Sbjct: 556 ERLLAHQKKH 565
Score = 97.1 bits (240), Expect = 1e-19
Identities = 87/313 (27%), Positives = 121/313 (38%), Gaps = 55/313 (17%)
Query: 1533 CSQCGKTYCQSGSLLNHN----TNKTDRHY-CLLCSKEFLNPVATKSHSHNHIDAQT-FA 1586
C +CG+ + + L H D + C LC + F VA H H A+ A
Sbjct: 87 CPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIA 146
Query: 1587 CPDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGE------DQVVLPGQGK 1640
CP C + F ++L +HL+ R H P EAR G DQ+V +
Sbjct: 147 CPKCERRFWRRKQLRAHLR---RCHPPAP----EARPFICGNCGRSFAQWDQLVAHKRVH 199
Query: 1641 AQEAPSETPR---GPGESVERARGGQAVTSM--AAEDKERPFRCTQCGRSYRHAGSLLNH 1695
EA E GP R RG AVT+ + +RPF+C CG+ +RH +L+ H
Sbjct: 200 VAEALEEAAAKALGP-----RPRGRPAVTAPRPGGDAVDRPFQCACCGKRFRHKPNLIAH 254
Query: 1696 QKAHT-TGLYPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVH 1754
++ HT + C C K N L +H R HT K + C CG+ FR L H ++H
Sbjct: 255 RRVHTGERPHQCPECGKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIH 314
Query: 1755 APREGPFTCPHCPRHFRRRISFVQHQQQHQEEWTVAGSGAPVAPVTGRGDLPLPPPPTPT 1814
EG G G+P P + P P P
Sbjct: 315 KRSEG-------------------------SAQAAPGPGSPQLPAGPQESAAEPTPAVPL 349
Query: 1815 TPLLDPSPQWPAD 1827
P +P P P +
Sbjct: 350 KPAQEPPPGAPPE 362
Score = 94.7 bits (234), Expect = 7e-19
Identities = 125/522 (23%), Positives = 182/522 (34%), Gaps = 74/522 (14%)
Query: 1297 RPFRCGQCGRTYRHAGSLLNH-RRSHETGQYSCPTCPKTYSNRMALKDHQRLHSENRRRR 1355
R RC C R + +L H RR CP C + + + L H+++H
Sbjct: 55 RAHRCAHCRRHFPGWVALWLHTRRCQARLPLPCPECGRRFRHAPFLALHRQVH------- 107
Query: 1356 AGRSRRTAVRCALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASEANLTGSQG 1415
A + C LCG+SF G +L HLR H +R A E +
Sbjct: 108 AAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKRPIA--------CPKCERRFWRRKQ 159
Query: 1416 LETQLGGAEPV-----PHLEDGVPRPGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGGG 1470
L L P P + R + + E L A KA
Sbjct: 160 LRAHLRRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEALEEAAAKA-------- 211
Query: 1471 LGNHSGGWVPQFLTRSEEPEDSVHRSPCHAGDCQLNGPTLSHMDSW-DNRDNSSQLQPGS 1529
LG G +T D+V R C G H + +R + +P
Sbjct: 212 LGPRPRG--RPAVTAPRPGGDAVDR----PFQCACCGKRFRHKPNLIAHRRVHTGERPHQ 265
Query: 1530 HSSCSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHS--HNHIDAQTF 1585
C GK + L +H T + C C + F + SHS H +
Sbjct: 266 CPEC---GKRFTNKPYLTSHRRIHTGEKPYPCKECGRRFRHKPNLLSHSKIHKRSEGSAQ 322
Query: 1586 ACPDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGT----GEDQVVLPGQ--- 1638
A P G S Q A ++ A VP ++ A++P G +D + P
Sbjct: 323 AAPGPG----SPQLPAGPQESAAEPTPAVP--LKPAQEPPPGAPPEHPQDPIEAPPSLYS 376
Query: 1639 ----GKA--------QEAPSETPRGPGESVERARGGQAVTSMAAEDK----ERPFRCTQC 1682
G++ T P E + T + A + ERPF C +C
Sbjct: 377 CDDCGRSFRLERFLRAHQRQHTGERPFTCAECGKNFGKKTHLVAHSRVHSGERPFACEEC 436
Query: 1683 GRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAF 1741
GR + L H++ H + C C K + L H R HT K + C CGKAF
Sbjct: 437 GRRFSQGSHLAAHRRDHAPDRPFVCPDCGKAFRHKPYLAAHRRIHTGEKPYVCPDCGKAF 496
Query: 1742 RTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQH 1783
+ L H R+H E P+ CP C R F ++ + + H++ H
Sbjct: 497 SQKSNLVSHRRIHT-GERPYACPDCDRSFSQKSNLITHRKSH 537
Score = 64.7 bits (156), Expect = 8e-10
Identities = 44/144 (30%), Positives = 62/144 (43%), Gaps = 9/144 (6%)
Query: 1676 PFRCTQCGRSYRHAGSLLNHQKAHTTGL----YPCSLCPKLLPNLLSLKNHSRTHTDPKR 1731
P C +CGR +RHA L H++ H + C LC + ++L H R H+ KR
Sbjct: 84 PLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAHSAAKR 143
Query: 1732 H-CCSICGKAFRTAARLEGH-GRVH--APREGPFTCPHCPRHFRRRISFVQHQQQHQEEW 1787
C C + F +L H R H AP PF C +C R F + V H++ H E
Sbjct: 144 PIACPKCERRFWRRKQLRAHLRRCHPPAPEARPFICGNCGRSFAQWDQLVAHKRVHVAEA 203
Query: 1788 TVAGSGAPVAP-VTGRGDLPLPPP 1810
+ + P GR + P P
Sbjct: 204 LEEAAAKALGPRPRGRPAVTAPRP 227
Score = 57.8 bits (138), Expect = 1e-07
Identities = 42/145 (28%), Positives = 59/145 (40%), Gaps = 7/145 (4%)
Query: 1639 GKAQEAPSETPRGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKA 1698
G +QE+P + ES + G +V A+ R RC C R + +L H +
Sbjct: 22 GPSQESPQTLGK---ESRGLRQQGTSVAQSGAQAPGRAHRCAHCRRHFPGWVALWLHTRR 78
Query: 1699 HTTGL-YPCSLCPKLLPNLLSLKNHSRTH---TDPKRHCCSICGKAFRTAARLEGHGRVH 1754
L PC C + + L H + H T C +CG++FR L H R H
Sbjct: 79 CQARLPLPCPECGRRFRHAPFLALHRQVHAAATPDLGFACHLCGQSFRGWVALVLHLRAH 138
Query: 1755 APREGPFTCPHCPRHFRRRISFVQH 1779
+ + P CP C R F RR H
Sbjct: 139 SAAKRPIACPKCERRFWRRKQLRAH 163
Score = 57.8 bits (138), Expect = 1e-07
Identities = 36/100 (36%), Positives = 45/100 (45%), Gaps = 14/100 (14%)
Query: 3 DTPPSL-SCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPG 61
+ PPSL SC DC R F R L Q + E RP+ C +CG+ +
Sbjct: 369 EAPPSLYSCDDCGRSF-------RLERFLRAHQRQHTGE-----RPFTCAECGKNFGKKT 416
Query: 62 SLVNHRRTHE-TGLFPCTTCGKDFSNPMALKSHMRTHAPE 100
LV H R H F C CG+ FS L +H R HAP+
Sbjct: 417 HLVAHSRVHSGERPFACEECGRRFSQGSHLAAHRRDHAPD 456
>gi|34419633 zinc finger protein 135 [Homo sapiens]
Length = 658
Score = 178 bits (451), Expect = 5e-44
Identities = 132/480 (27%), Positives = 202/480 (42%), Gaps = 79/480 (16%)
Query: 235 EERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRP 293
+E+ YKC +CGK + H+ +L H ++HT Y C C K F N AL H R+H +P
Sbjct: 210 KEKPYKCQECGKAFSHSSALIEHHRTHTGERPYECHECLKGFRNSSALTKHQRIHTGEKP 269
Query: 294 YHCPHCPRVFRLPRELLEHQQSHEGER--------QEPRWEEKGMPTTNGHTDESSQDQL 345
Y C C R F L++HQ++H GE+ + + HT E +
Sbjct: 270 YKCTQCGRTFNQIAPLIQHQRTHTGEKPYECSECGKSFSFRSSFSQHERTHTGEKPYECS 329
Query: 346 PSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPC 403
+ S L+ + +P++CG+CG+ + H+ SL H++ H TG Y C
Sbjct: 330 ECGKAFRQSIHLTQHLRIHTG----EKPYQCGECGKAFSHSSSLTKHQRIH-TGEKPYEC 384
Query: 404 SLCSKQLFNAAALKNHVRAH--HRPRQGVGENGQPSVPPAPLLLAETTHKEE-------- 453
C K L H R H +P + GE G+ L H E
Sbjct: 385 HECGKAFTQITPLIQHQRTHTGEKPYE-CGECGKAFSQSTLLTEHRRIHTGEKPYGCNEC 443
Query: 454 -----------EDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRK 500
+ T +PY+CS+CG+A+R L H+ H TGE Y+C+ C +
Sbjct: 444 GKTFSHSSSLSQHERTHTGEKPYECSQCGKAFRQSTHLTQHQRIH-TGEKPYECNDCGKA 502
Query: 501 YPNLMALRNHVRVH-------CKAARRSADIGAEGAP--SHLKVELPPDPVEAE--AAPH 549
+ + +L H R+H C R+ ++ AP H ++ P E
Sbjct: 503 FSHSSSLTKHQRIHTGEKPYECNQCGRAF---SQLAPLIQHQRIHTGEKPYECNQCGRAF 559
Query: 550 TDQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTET 609
+ + +H+ T K + C+ CG F + SL +H TH GEK
Sbjct: 560 SQSSLLIEHQRIHT-------KEKPYGCNECGKSFSHSSSLSQHERTH-TGEK------- 604
Query: 610 TMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHS 667
+ C DCGKS+R S L HR+ H TG+ ++C C K F +++ H R H+
Sbjct: 605 ------PYECHDCGKSFRQSTHLTQHRRIH-TGEKPYACRDCGKAFTHSSSLTKHQRTHT 657
Score = 162 bits (409), Expect = 4e-39
Identities = 138/547 (25%), Positives = 213/547 (38%), Gaps = 106/547 (19%)
Query: 1178 KGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQAC 1235
+G+ +P L +K C E+P+ C+ CG+++ H+ +LI H ++H TG + C C
Sbjct: 193 RGKREKPDLNVLQKTCV----KEKPYKCQECGKAFSHSSALIEHHRTH-TGERPYECHEC 247
Query: 1236 SKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHME------------- 1282
KGF N +L H+RIH + ++C++CG+ F L HQR H
Sbjct: 248 LKGFRNSSALTKHQRIHTGEKPYKCTQCGRTFNQIAPLIQHQRTHTGEKPYECSECGKSF 307
Query: 1283 --RRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNR 1338
R + ++P+ C +CG+ +R + L H R H TG+ Y C C K +S+
Sbjct: 308 SFRSSFSQHERTHTGEKPYECSECGKAFRQSIHLTQHLRIH-TGEKPYQCGECGKAFSHS 366
Query: 1339 MALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHEETEREPANGQG 1398
+L HQR+H+ + C CG++F L +H R H T +P +
Sbjct: 367 SSLTKHQRIHTGEK----------PYECHECGKAFTQITPLIQHQRTH--TGEKPY--EC 412
Query: 1399 GLDGTAASEAN-LTGSQGLETQLGGAEPVPHLEDGVPRPGERSQSP-IRAASSEAPEPLS 1456
G G A S++ LT + + T G +P E G S S R + E P S
Sbjct: 413 GECGKAFSQSTLLTEHRRIHT---GEKPYGCNECGKTFSHSSSLSQHERTHTGEKPYECS 469
Query: 1457 WGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSPCHAGDCQLNGPTLSHMDSW 1516
GKA Q ++ P DC G SH S
Sbjct: 470 -QCGKA----------------FRQSTHLTQHQRIHTGEKPYECNDC---GKAFSHSSSL 509
Query: 1517 DNRDNSSQLQPGSHS-SCSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATK 1573
++ G C+QCG+ + Q L+ H T + C C + F
Sbjct: 510 TKH---QRIHTGEKPYECNQCGRAFSQLAPLIQHQRIHTGEKPYECNQCGRAFSQSSLLI 566
Query: 1574 SHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQV 1633
H H + + C +CGK+F L+ H + H TGE
Sbjct: 567 EHQRIHTKEKPYGCNECGKSFSHSSSLSQHERTH--------------------TGEKPY 606
Query: 1634 VLPGQGKAQEAPSETPRGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLL 1693
GK+ + + R G E+P+ C CG+++ H+ SL
Sbjct: 607 ECHDCGKSFRQSTHLTQH-----RRIHTG-----------EKPYACRDCGKAFTHSSSLT 650
Query: 1694 NHQKAHT 1700
HQ+ HT
Sbjct: 651 KHQRTHT 657
Score = 158 bits (400), Expect = 4e-38
Identities = 135/496 (27%), Positives = 200/496 (40%), Gaps = 78/496 (15%)
Query: 46 RPYRCQQCGRGYRHPGSLVNHRRTHETGLFP--CTTCGKDFSNPMALKSHMRTHAPE--- 100
+PY+CQ+CG+ + H +L+ H RTH TG P C C K F N AL H R H E
Sbjct: 212 KPYKCQECGKAFSHSSALIEHHRTH-TGERPYECHECLKGFRNSSALTKHQRIHTGEKPY 270
Query: 101 -----GRRRHR-PPRPKEATPHLQGETVSTDSWGQRLGSSEGW-ENQTKHTEETP-DCES 152
GR ++ P + H + G+ + +++ HT E P +C
Sbjct: 271 KCTQCGRTFNQIAPLIQHQRTHTGEKPYECSECGKSFSFRSSFSQHERTHTGEKPYECSE 330
Query: 153 VPDPRAASGTWEDLPTRQREGLASHPGPEDGADGWGPSTNSARAPPLPIPASSLLSNLEQ 212
S + L H G + G S +SSL +
Sbjct: 331 CGKAFRQS-------IHLTQHLRIHTGEKPYQCGECGKAFS--------HSSSLTKHQRI 375
Query: 213 YLAESVVN-FTGGQEPTQSPPAEEERR-------YKCSQCGKTYKHAGSLTNHRQSHT-L 263
+ E G+ TQ P + +R Y+C +CGK + + LT HR+ HT
Sbjct: 376 HTGEKPYECHECGKAFTQITPLIQHQRTHTGEKPYECGECGKAFSQSTLLTEHRRIHTGE 435
Query: 264 GIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQEP 323
Y C C K FS+ +L H R H +PY C C + FR L +HQ+ H GE+
Sbjct: 436 KPYGCNECGKTFSHSSSLSQHERTHTGEKPYECSQCGKAFRQSTHLTQHQRIHTGEKP-- 493
Query: 324 RWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTY 383
+E H+ ++ Q +GE +P+ C CGR +
Sbjct: 494 -YECNDCGKAFSHSSSLTKHQ------------RIHTGE---------KPYECNQCGRAF 531
Query: 384 RHAGSLINHRKSHQTG--VYPCSLCSKQLFNAAALKNHVRAHHRPR-QGVGENGQPSVPP 440
LI H++ H TG Y C+ C + ++ L H R H + + G E G+
Sbjct: 532 SQLAPLIQHQRIH-TGEKPYECNQCGRAFSQSSLLIEHQRIHTKEKPYGCNECGKSFSHS 590
Query: 441 APLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCP 498
+ L E TH E +PY+C +CG+++R L HR H TGE Y C C
Sbjct: 591 SSLSQHERTHTGE---------KPYECHDCGKSFRQSTHLTQHRRIH-TGEKPYACRDCG 640
Query: 499 RKYPNLMALRNHVRVH 514
+ + + +L H R H
Sbjct: 641 KAFTHSSSLTKHQRTH 656
Score = 146 bits (369), Expect = 2e-34
Identities = 99/362 (27%), Positives = 157/362 (43%), Gaps = 54/362 (14%)
Query: 1050 RPFRCNQCGKTYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGS 1107
+P++C QCG+T+ L+ H++ H TG+ + C C + + +++ H R H G
Sbjct: 268 KPYKCTQCGRTFNQIAPLIQHQRTH-TGEKPYECSECGKSFSFRSSFSQHERTHT---GE 323
Query: 1108 EP-QVGPIPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVAR 1166
+P + +A S + KP E G + L + ++ E
Sbjct: 324 KPYECSECGKAFRQSIHLTQHLRIHTGEKPYQCGECGKAFSHSSSLTKHQRIHTGE---- 379
Query: 1167 VKEEVWEETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQ 1226
K E +I P ++ Q + E+P+ C CG+++ + L HR+ H
Sbjct: 380 -KPYECHECGKAFTQITPLIQH-----QRTHTGEKPYECGECGKAFSQSTLLTEHRRIH- 432
Query: 1227 TGH--FGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERR 1284
TG +GC C K FS+ SL H R H + + CS+CGKAFR L HQR+H
Sbjct: 433 TGEKPYGCNECGKTFSHSSSLSQHERTHTGEKPYECSQCGKAFRQSTHLTQHQRIH---- 488
Query: 1285 GGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALK 1342
++P+ C CG+ + H+ SL H+R H TG+ Y C C + +S L
Sbjct: 489 ---------TGEKPYECNDCGKAFSHSSSLTKHQRIH-TGEKPYECNQCGRAFSQLAPLI 538
Query: 1343 DHQRLHSENRR---RRAGR---------------SRRTAVRCALCGRSFPGRGSLERHLR 1384
HQR+H+ + + GR ++ C CG+SF SL +H R
Sbjct: 539 QHQRIHTGEKPYECNQCGRAFSQSSLLIEHQRIHTKEKPYGCNECGKSFSHSSSLSQHER 598
Query: 1385 EH 1386
H
Sbjct: 599 TH 600
Score = 139 bits (351), Expect = 2e-32
Identities = 101/381 (26%), Positives = 165/381 (43%), Gaps = 64/381 (16%)
Query: 1050 RPFRCNQCGKTYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGS 1107
+P+ C++CGK++ S H + H TG+ + C C + + HLR H G
Sbjct: 296 KPYECSECGKSFSFRSSFSQHERTH-TGEKPYECSECGKAFRQSIHLTQHLRIHT---GE 351
Query: 1108 EP-QVGPIPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVAR 1166
+P Q G +A S KP E G ++ L + + E+
Sbjct: 352 KPYQCGECGKAFSHSSSLTKHQRIHTGEKPYECHECGKAFTQITPLIQHQRTHTGEKPYE 411
Query: 1167 VKE--EVWEETTVKGEEIEPRLETAEK--GCQ------TEASS----------ERPFSCE 1206
E + + ++T+ E R+ T EK GC + +SS E+P+ C
Sbjct: 412 CGECGKAFSQSTLLTEH--RRIHTGEKPYGCNECGKTFSHSSSLSQHERTHTGEKPYECS 469
Query: 1207 VCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECG 1264
CG++++ + L H++ H TG + C C K FS+ SL H+RIH + + C++CG
Sbjct: 470 QCGKAFRQSTHLTQHQRIH-TGEKPYECNDCGKAFSHSSSLTKHQRIHTGEKPYECNQCG 528
Query: 1265 KAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRSHETG 1324
+AF L HQR+H ++P+ C QCGR + + L+ H+R H
Sbjct: 529 RAFSQLAPLIQHQRIHTG-------------EKPYECNQCGRAFSQSSLLIEHQRIHTKE 575
Query: 1325 Q-YSCPTCPKTYSNRMALKDHQRLHSENRR---RRAGRSRRTAVR--------------- 1365
+ Y C C K++S+ +L H+R H+ + G+S R +
Sbjct: 576 KPYGCNECGKSFSHSSSLSQHERTHTGEKPYECHDCGKSFRQSTHLTQHRRIHTGEKPYA 635
Query: 1366 CALCGRSFPGRGSLERHLREH 1386
C CG++F SL +H R H
Sbjct: 636 CRDCGKAFTHSSSLTKHQRTH 656
Score = 139 bits (350), Expect = 3e-32
Identities = 123/524 (23%), Positives = 204/524 (38%), Gaps = 102/524 (19%)
Query: 848 YQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHRRQAHSSS 907
Y+C C K F AL H + H T +P+ C C F + H+R H+
Sbjct: 214 YKCQECGKAFSHSSALIEHHRTH-----TGERPYECHECLKGFRNSSALTKHQR-IHT-- 265
Query: 908 GMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSAGYGHICGCCGQTY 967
GE+ P + + ++ +Q + Y C CG+++
Sbjct: 266 ---------GEK-------PYKCTQCGRTFNQIAPLIQHQRTHTGEKPYE--CSECGKSF 307
Query: 968 DDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDIVNSVSGEGGDAKSQEG 1027
S +H ++ + + P G A +
Sbjct: 308 SFRSSFSQHERTHTG-----EKPYECSECGKAFRQSIH---------------------- 340
Query: 1028 AGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGD--FLCPVCS 1085
L L I GE +P++C +CGK + H SL H++IH TG+ + C C
Sbjct: 341 ----LTQHLRIHTGE-------KPYQCGECGKAFSHSSSLTKHQRIH-TGEKPYECHECG 388
Query: 1086 RCYPNLAAYRNHLRNHPRCKGSEP-QVGPIPEAAGSSELQVGPIPEGGSNKPQHMAEEGP 1144
+ + + H R H G +P + G +A S L ++ H E+
Sbjct: 389 KAFTQITPLIQHQRTHT---GEKPYECGECGKAFSQSTLLT-------EHRRIHTGEKPY 438
Query: 1145 GQAEVEKLQEELKVEPLEEVARVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSERPFS 1204
G E K E E+ +E + G+ + Q + E+P+
Sbjct: 439 GCNECGKTFSHSSSLSQHERTHTGEKPYECSQC-GKAFRQSTHLTQH--QRIHTGEKPYE 495
Query: 1205 CEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPRRFRCSE 1262
C CG+++ H+ SL H++ H TG + C C + FS L L H+RIH + + C++
Sbjct: 496 CNDCGKAFSHSSSLTKHQRIH-TGEKPYECNQCGRAFSQLAPLIQHQRIHTGEKPYECNQ 554
Query: 1263 CGKAFRLRKQLASHQRVHMERRGGGGTR---------------KATREDRPFRCGQCGRT 1307
CG+AF L HQR+H + + G + ++P+ C CG++
Sbjct: 555 CGRAFSQSSLLIEHQRIHTKEKPYGCNECGKSFSHSSSLSQHERTHTGEKPYECHDCGKS 614
Query: 1308 YRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHS 1349
+R + L HRR H TG+ Y+C C K +++ +L HQR H+
Sbjct: 615 FRQSTHLTQHRRIH-TGEKPYACRDCGKAFTHSSSLTKHQRTHT 657
Score = 131 bits (329), Expect = 7e-30
Identities = 124/483 (25%), Positives = 174/483 (36%), Gaps = 65/483 (13%)
Query: 1326 YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLRE 1385
Y C C K +S+ AL +H R H+ R C C + F +L +H R
Sbjct: 214 YKCQECGKAFSHSSALIEHHRTHTGER----------PYECHECLKGFRNSSALTKHQRI 263
Query: 1386 HEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRPGERSQSPI- 1444
H + G T A L Q T G +P E G S S
Sbjct: 264 HTGEKPYKCTQCGR---TFNQIAPLIQHQRTHT---GEKPYECSECGKSFSFRSSFSQHE 317
Query: 1445 RAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSPCHAGDCQ 1504
R + E P S GKA Q + ++ P G+C
Sbjct: 318 RTHTGEKPYECS-ECGKA----------------FRQSIHLTQHLRIHTGEKPYQCGEC- 359
Query: 1505 LNGPTLSHMDSWDNRDNSSQLQPGSHS-SCSQCGKTYCQSGSLLNHNTNKTDR--HYCLL 1561
G SH S ++ G C +CGK + Q L+ H T + C
Sbjct: 360 --GKAFSHSSSLTKHQ---RIHTGEKPYECHECGKAFTQITPLIQHQRTHTGEKPYECGE 414
Query: 1562 CSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQVPAQMEEA 1621
C K F H H + + C +CGK F L+ H + H +Q +A
Sbjct: 415 CGKAFSQSTLLTEHRRIHTGEKPYGCNECGKTFSHSSSLSQHERTHTGEKPYECSQCGKA 474
Query: 1622 --------RDPKAGTGEDQVVLPGQGKAQEAPSE--------TPRGPGESVERARGGQAV 1665
+ + TGE GKA S T P E + R +
Sbjct: 475 FRQSTHLTQHQRIHTGEKPYECNDCGKAFSHSSSLTKHQRIHTGEKPYECNQCGRAFSQL 534
Query: 1666 TSMAAEDK----ERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLK 1720
+ + E+P+ C QCGR++ + L+ HQ+ HT Y C+ C K + SL
Sbjct: 535 APLIQHQRIHTGEKPYECNQCGRAFSQSSLLIEHQRIHTKEKPYGCNECGKSFSHSSSLS 594
Query: 1721 NHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQ 1780
H RTHT K + C CGK+FR + L H R+H E P+ C C + F S +HQ
Sbjct: 595 QHERTHTGEKPYECHDCGKSFRQSTHLTQHRRIHT-GEKPYACRDCGKAFTHSSSLTKHQ 653
Query: 1781 QQH 1783
+ H
Sbjct: 654 RTH 656
Score = 129 bits (325), Expect = 2e-29
Identities = 107/422 (25%), Positives = 162/422 (38%), Gaps = 76/422 (18%)
Query: 266 YPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQEPRW 325
Y C C K FS+ AL H R H RPY C C + FR L +HQ+
Sbjct: 214 YKCQECGKAFSHSSALIEHHRTHTGERPYECHECLKGFRNSSALTKHQRI---------- 263
Query: 326 EEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRH 385
HT E + N A L +P+ C +CG+++
Sbjct: 264 ----------HTGEKPYKCTQCGRTFNQIAPLIQHQRTHTGE----KPYECSECGKSFSF 309
Query: 386 AGSLINHRKSHQTGV--YPCSLCSKQLFNAAALKNHVRAH--HRPRQGVGENGQPSVPPA 441
S H ++H TG Y CS C K + L H+R H +P Q GE G+ +
Sbjct: 310 RSSFSQHERTH-TGEKPYECSECGKAFRQSIHLTQHLRIHTGEKPYQ-CGECGKAFSHSS 367
Query: 442 PLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPR 499
L + H E +PY+C ECG+A+ L+ H+ +H TGE Y+C C +
Sbjct: 368 SLTKHQRIHTGE---------KPYECHECGKAFTQITPLIQHQRTH-TGEKPYECGECGK 417
Query: 500 KYPNLMALRNHVRVH-------CKAARRSADIGAEGAPSHLKVELPPDPVEAEAAPHT-- 550
+ L H R+H C ++ + H + P E
Sbjct: 418 AFSQSTLLTEHRRIHTGEKPYGCNECGKTFS-HSSSLSQHERTHTGEKPYECSQCGKAFR 476
Query: 551 DQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTETT 610
H+ +H+ T P + C+ CG F + SL +H H GEK
Sbjct: 477 QSTHLTQHQRIHTGEKP-------YECNDCGKAFSHSSSLTKHQRIH-TGEKP------- 521
Query: 611 MSPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHSR 668
+ C CG+++ LI H++ H TG+ + C C + F + + H R H++
Sbjct: 522 ------YECNQCGRAFSQLAPLIQHQRIH-TGEKPYECNQCGRAFSQSSLLIEHQRIHTK 574
Query: 669 RR 670
+
Sbjct: 575 EK 576
Score = 128 bits (322), Expect = 4e-29
Identities = 83/280 (29%), Positives = 118/280 (42%), Gaps = 30/280 (10%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C+QCG+T+ Q L+ H T + C C K F + H H + + C +C
Sbjct: 272 CTQCGRTFNQIAPLIQHQRTHTGEKPYECSECGKSFSFRSSFSQHERTHTGEKPYECSEC 331
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEA-----------RDPKAGTGEDQVVLPGQG 1639
GKAF L HL+ H + P Q E + + TGE G
Sbjct: 332 GKAFRQSIHLTQHLRIHT---GEKPYQCGECGKAFSHSSSLTKHQRIHTGEKPYECHECG 388
Query: 1640 KA--------QEAPSETPRGPGESVERARGGQAVTSMAAEDK----ERPFRCTQCGRSYR 1687
KA Q + T P E E + T + + E+P+ C +CG+++
Sbjct: 389 KAFTQITPLIQHQRTHTGEKPYECGECGKAFSQSTLLTEHRRIHTGEKPYGCNECGKTFS 448
Query: 1688 HAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAAR 1746
H+ SL H++ HT Y CS C K L H R HT K + C+ CGKAF ++
Sbjct: 449 HSSSLSQHERTHTGEKPYECSQCGKAFRQSTHLTQHQRIHTGEKPYECNDCGKAFSHSSS 508
Query: 1747 LEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
L H R+H E P+ C C R F + +QHQ+ H E
Sbjct: 509 LTKHQRIHTG-EKPYECNQCGRAFSQLAPLIQHQRIHTGE 547
Score = 124 bits (311), Expect = 8e-28
Identities = 116/429 (27%), Positives = 172/429 (40%), Gaps = 87/429 (20%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
CS+C + F S+H E + +PY C +CG+ +R L H R
Sbjct: 300 CSECGKSFSFRSSFSQH------------ERTHTGEKPYECSECGKAFRQSIHLTQHLRI 347
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHLQGETVSTDSW 127
H TG P C CGK FS+ +L H R H E +P E H G+ +
Sbjct: 348 H-TGEKPYQCGECGKAFSHSSSLTKHQRIHTGE--------KPYEC--HECGKAFTQ--- 393
Query: 128 GQRLGSSEGWENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQREGLASHPGPED-GAD 185
+ ++Q HT E P +C G T E H G + G +
Sbjct: 394 -----ITPLIQHQRTHTGEKPYEC-------GECGKAFSQSTLLTEHRRIHTGEKPYGCN 441
Query: 186 GWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTG-GQEPTQSPPAEEERR------ 238
G + + +SSL + + E + G+ QS + +R
Sbjct: 442 ECGKTFSH---------SSSLSQHERTHTGEKPYECSQCGKAFRQSTHLTQHQRIHTGEK 492
Query: 239 -YKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHC 296
Y+C+ CGK + H+ SLT H++ HT Y C C + FS L L H R+H +PY C
Sbjct: 493 PYECNDCGKAFSHSSSLTKHQRIHTGEKPYECNQCGRAFSQLAPLIQHQRIHTGEKPYEC 552
Query: 297 PHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAE 356
C R F L+EHQ+ H E+ + + H+ SQ E
Sbjct: 553 NQCGRAFSQSSLLIEHQRIHTKEKP---YGCNECGKSFSHSSSLSQH------------E 597
Query: 357 LSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFNAA 414
+ +GE +P+ C DCG+++R + L HR+ H TG Y C C K +++
Sbjct: 598 RTHTGE---------KPYECHDCGKSFRQSTHLTQHRRIH-TGEKPYACRDCGKAFTHSS 647
Query: 415 ALKNHVRAH 423
+L H R H
Sbjct: 648 SLTKHQRTH 656
Score = 121 bits (303), Expect = 7e-27
Identities = 74/257 (28%), Positives = 115/257 (44%), Gaps = 12/257 (4%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKT-DRHY-CLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C +CGK + S +L+ H+ T +R Y C C K F N A H H + + C C
Sbjct: 216 CQECGKAFSHSSALIEHHRTHTGERPYECHECLKGFRNSSALTKHQRIHTGEKPYKCTQC 275
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPR 1650
G+ F L H + H ++ ++ ++ + + G+ K E SE +
Sbjct: 276 GRTFNQIAPLIQHQRTHTGEKPYECSECGKSFSFRSSFSQHERTHTGE-KPYEC-SECGK 333
Query: 1651 GPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLC 1709
+S+ + + E+P++C +CG+++ H+ SL HQ+ HT Y C C
Sbjct: 334 AFRQSIHLTQ------HLRIHTGEKPYQCGECGKAFSHSSSLTKHQRIHTGEKPYECHEC 387
Query: 1710 PKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRH 1769
K + L H RTHT K + C CGKAF + L H R+H E P+ C C +
Sbjct: 388 GKAFTQITPLIQHQRTHTGEKPYECGECGKAFSQSTLLTEHRRIHT-GEKPYGCNECGKT 446
Query: 1770 FRRRISFVQHQQQHQEE 1786
F S QH++ H E
Sbjct: 447 FSHSSSLSQHERTHTGE 463
Score = 118 bits (295), Expect = 6e-26
Identities = 78/280 (27%), Positives = 119/280 (42%), Gaps = 30/280 (10%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
CS+CGK++ S H T + C C K F + H H + + C +C
Sbjct: 300 CSECGKSFSFRSSFSQHERTHTGEKPYECSECGKAFRQSIHLTQHLRIHTGEKPYQCGEC 359
Query: 1591 GKAFESHQELASHLQAHA-----------RGHSQVPAQMEEARDPKAGTGEDQVVLPGQG 1639
GKAF L H + H + +Q+ ++ R TGE G
Sbjct: 360 GKAFSHSSSLTKHQRIHTGEKPYECHECGKAFTQITPLIQHQR---THTGEKPYECGECG 416
Query: 1640 KA--------QEAPSETPRGPGESVERARGGQAVTSMAAEDK----ERPFRCTQCGRSYR 1687
KA + T P E + +S++ ++ E+P+ C+QCG+++R
Sbjct: 417 KAFSQSTLLTEHRRIHTGEKPYGCNECGKTFSHSSSLSQHERTHTGEKPYECSQCGKAFR 476
Query: 1688 HAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAAR 1746
+ L HQ+ HT Y C+ C K + SL H R HT K + C+ CG+AF A
Sbjct: 477 QSTHLTQHQRIHTGEKPYECNDCGKAFSHSSSLTKHQRIHTGEKPYECNQCGRAFSQLAP 536
Query: 1747 LEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
L H R+H E P+ C C R F + ++HQ+ H +E
Sbjct: 537 LIQHQRIHTG-EKPYECNQCGRAFSQSSLLIEHQRIHTKE 575
Score = 110 bits (274), Expect = 2e-23
Identities = 132/536 (24%), Positives = 199/536 (37%), Gaps = 104/536 (19%)
Query: 427 RQGVGENGQ--PSVPPAPLLLAET------THKEEEDPT------TTLDHRPYKCSECGR 472
R G GEN P +P P+ T + E P T + +PYKC ECG+
Sbjct: 162 RNGFGENISLNPDLPHQPMTPERQSPHTWGTRGKREKPDLNVLQKTCVKEKPYKCQECGK 221
Query: 473 AYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVH-------CKAARRSAD 523
A+ H +L+ H +H TGE Y+C C + + N AL H R+H C R+ +
Sbjct: 222 AFSHSSALIEHHRTH-TGERPYECHECLKGFRNSSALTKHQRIHTGEKPYKCTQCGRTFN 280
Query: 524 IGAEGAP--SHLKVELPPDPVEAE--AAPHTDQDHVCKHEEEATDITPAADKTAAHICSI 579
+ AP H + P E + + +HE T P + CS
Sbjct: 281 ---QIAPLIQHQRTHTGEKPYECSECGKSFSFRSSFSQHERTHTGEKP-------YECSE 330
Query: 580 CGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTH 639
CG F + L +H H GEK + C +CGK++ HS SL H++ H
Sbjct: 331 CGKAFRQSIHLTQHLRIH-TGEK-------------PYQCGECGKAFSHSSSLTKHQRIH 376
Query: 640 QTGD--FSCGACAKHFHTMAAMKNHLRRHSRRRSRRHRKRAGGASGGREAKLLAAESWTR 697
TG+ + C C K F + + H R H+ + G G A S +
Sbjct: 377 -TGEKPYECHECGKAFTQITPLIQHQRTHTGEKPYE-----CGECG-------KAFSQST 423
Query: 698 ELEDNEGLESPQDPSGESPHGAEGNLESDGDCLQAESEGDK------CGLE-RDETHF-- 748
L ++ + + + P G + G + S + G+K CG R TH
Sbjct: 424 LLTEHRRIHTGEKPYGCNECGKTFSHSSSLSQHERTHTGEKPYECSQCGKAFRQSTHLTQ 483
Query: 749 -----QGDK--ESGGTGEGLERKDASLLDNLDIPGEEGGGTHFC----DSLTGVDEDQKP 797
G+K E G+ + GE+ + C L + + Q+
Sbjct: 484 HQRIHTGEKPYECNDCGKAFSHSSSLTKHQRIHTGEKPYECNQCGRAFSQLAPLIQHQRI 543
Query: 798 ATGQ-PNSSSHSANAVTGWQAGAAHT----------CSDCGHSFPHATGLLSHRPCHP-P 845
TG+ P + A + H C++CG SF H++ L H H
Sbjct: 544 HTGEKPYECNQCGRAFSQSSLLIEHQRIHTKEKPYGCNECGKSFSHSSSLSQHERTHTGE 603
Query: 846 GIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHRR 901
Y+C C K F L H + H T +P+ C CG F + H+R
Sbjct: 604 KPYECHDCGKSFRQSTHLTQHRRIH-----TGEKPYACRDCGKAFTHSSSLTKHQR 654
Score = 93.6 bits (231), Expect = 2e-18
Identities = 104/438 (23%), Positives = 151/438 (34%), Gaps = 113/438 (25%)
Query: 821 HTCSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQ 879
+ CS+CG +F + L H H YQC C K F +L H + H T +
Sbjct: 326 YECSECGKAFRQSIHLTQHLRIHTGEKPYQCGECGKAFSHSSSLTKHQRIH-----TGEK 380
Query: 880 PFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAE 939
P+ C CG F H+R T E+ E E A S L+E
Sbjct: 381 PYECHECGKAFTQITPLIQHQR--------THTGEKPYE---CGECGKAFSQSTLLTEHR 429
Query: 940 LLNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDA 999
++ ++ YG C CG+T+ SL +H + T + P G A
Sbjct: 430 RIHTGEKP--------YG--CNECGKTFSHSSSLSQHER-----THTGEKPYECSQCGKA 474
Query: 1000 MEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGK 1059
T L I GE +P+ CN CGK
Sbjct: 475 FRQ--------------------------STHLTQHQRIHTGE-------KPYECNDCGK 501
Query: 1060 TYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEP-QVGPIPE 1116
+ H SL H++IH TG+ + C C R + LA H R H G +P +
Sbjct: 502 AFSHSSSLTKHQRIH-TGEKPYECNQCGRAFSQLAPLIQHQRIH---TGEKPYECNQCGR 557
Query: 1117 AAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKEEVWEETT 1176
A S L + KP E G + L + +
Sbjct: 558 AFSQSSLLIEHQRIHTKEKPYGCNECGKSFSHSSSLSQHERTH----------------- 600
Query: 1177 VKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQA 1234
+ E+P+ C CG+S++ + L HR+ H TG + C+
Sbjct: 601 ---------------------TGEKPYECHDCGKSFRQSTHLTQHRRIH-TGEKPYACRD 638
Query: 1235 CSKGFSNLMSLKNHRRIH 1252
C K F++ SL H+R H
Sbjct: 639 CGKAFTHSSSLTKHQRTH 656
Score = 93.6 bits (231), Expect = 2e-18
Identities = 87/331 (26%), Positives = 127/331 (38%), Gaps = 50/331 (15%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C + F L++H+ + + +PY C +CG+ + L+ H+RT
Sbjct: 356 CGECGKAFSHSSSLTKHQRI------------HTGEKPYECHECGKAFTQITPLIQHQRT 403
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHA---PEGRRR------HRPPRPKEATPHLQ 118
H TG P C CGK FS L H R H P G H + H
Sbjct: 404 H-TGEKPYECGECGKAFSQSTLLTEHRRIHTGEKPYGCNECGKTFSHSSSLSQHERTHTG 462
Query: 119 GETVSTDSWGQRLGSSEGW-ENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQREGLAS 176
+ G+ S ++Q HT E P +C D A L QR
Sbjct: 463 EKPYECSQCGKAFRQSTHLTQHQRIHTGEKPYECN---DCGKAFSHSSSLTKHQR----I 515
Query: 177 HPGPEDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTG-GQEPTQSPPAEE 235
H G + S AP L+ + + E G+ +QS E
Sbjct: 516 HTGEKPYECNQCGRAFSQLAP--------LIQHQRIHTGEKPYECNQCGRAFSQSSLLIE 567
Query: 236 ERR-------YKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRL 287
+R Y C++CGK++ H+ SL+ H ++HT Y C C K F L H R+
Sbjct: 568 HQRIHTKEKPYGCNECGKSFSHSSSLSQHERTHTGEKPYECHDCGKSFRQSTHLTQHRRI 627
Query: 288 HAQYRPYHCPHCPRVFRLPRELLEHQQSHEG 318
H +PY C C + F L +HQ++H G
Sbjct: 628 HTGEKPYACRDCGKAFTHSSSLTKHQRTHTG 658
Score = 90.1 bits (222), Expect = 2e-17
Identities = 43/115 (37%), Positives = 62/115 (53%), Gaps = 2/115 (1%)
Query: 1673 KERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLCPKLLPNLLSLKNHSRTHTDPKR 1731
KE+P++C +CG+++ H+ +L+ H + HT Y C C K N +L H R HT K
Sbjct: 210 KEKPYKCQECGKAFSHSSALIEHHRTHTGERPYECHECLKGFRNSSALTKHQRIHTGEKP 269
Query: 1732 HCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
+ C+ CG+ F A L H R H E P+ C C + F R SF QH++ H E
Sbjct: 270 YKCTQCGRTFNQIAPLIQHQRTHT-GEKPYECSECGKSFSFRSSFSQHERTHTGE 323
Score = 87.8 bits (216), Expect = 9e-17
Identities = 117/516 (22%), Positives = 192/516 (37%), Gaps = 89/516 (17%)
Query: 596 THGAGEKENSRT-ETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKH 652
T G EK + + T + + C++CGK++ HS +LI H +TH TG+ + C C K
Sbjct: 192 TRGKREKPDLNVLQKTCVKEKPYKCQECGKAFSHSSALIEHHRTH-TGERPYECHECLKG 250
Query: 653 FHTMAAMKNHLRRHSRRRSRRHRKRAGGASGGREAKLLAAESWTRELEDNEGLESPQDPS 712
F +A L +H +R K GR +A ++ + +
Sbjct: 251 FRNSSA----LTKH--QRIHTGEKPYKCTQCGRTFNQIAPL-----------IQHQRTHT 293
Query: 713 GESPHGAEGNLESDGDCLQAESEGDKCGLERDETHFQGDK--ESGGTGEGLERKDASLLD 770
GE P+ +C +S + + E G+K E G+ R+ L
Sbjct: 294 GEKPYECS-------EC--GKSFSFRSSFSQHERTHTGEKPYECSECGKAF-RQSIHLTQ 343
Query: 771 NLDIPGEEGGGTHFCDSLTGVDEDQKPATGQPNSSSHSANAVTGWQAGAA-HTCSDCGHS 829
+L I TG Q G+ S S S G + C +CG +
Sbjct: 344 HLRIH-------------TGEKPYQCGECGKAFSHSSSLTKHQRIHTGEKPYECHECGKA 390
Query: 830 FPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGM 888
F T L+ H+ H Y+C C K F L H + H T +P+ C CG
Sbjct: 391 FTQITPLIQHQRTHTGEKPYECGECGKAFSQSTLLTEHRRIH-----TGEKPYGCNECGK 445
Query: 889 IFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEE-GVAEAAPARSPPLQLSEAELLNQLQRE 947
F +HSSS GE+ ++ A L++ + ++ ++
Sbjct: 446 TF------------SHSSSLSQHERTHTGEKPYECSQCGKAFRQSTHLTQHQRIHTGEKP 493
Query: 948 VEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSV 1007
E C CG+ + SL +H + + + P G A + +
Sbjct: 494 YE----------CNDCGKAFSHSSSLTKHQRIHTG-----EKPYECNQCGRAFSQLAPLI 538
Query: 1008 LEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYRHGGSL 1067
+++ GE +Q G SL I+ + + +P+ CN+CGK++ H SL
Sbjct: 539 QHQRIHT--GEKPYECNQCGRAFSQS-SLLIE--HQRIHTKEKPYGCNECGKSFSHSSSL 593
Query: 1068 VNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNH 1101
H + H TG+ + C C + + H R H
Sbjct: 594 SQHERTH-TGEKPYECHDCGKSFRQSTHLTQHRRIH 628
Score = 87.0 bits (214), Expect = 1e-16
Identities = 62/221 (28%), Positives = 87/221 (39%), Gaps = 29/221 (13%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C++CGKT+ S SL H T + C C K F H H + + C DC
Sbjct: 440 CNECGKTFSHSSSLSQHERTHTGEKPYECSQCGKAFRQSTHLTQHQRIHTGEKPYECNDC 499
Query: 1591 GKAFESHQELASHLQAHA-----------RGHSQVPAQMEEARDPKAGTGEDQVVLPGQG 1639
GKAF L H + H R SQ+ ++ R TGE G
Sbjct: 500 GKAFSHSSSLTKHQRIHTGEKPYECNQCGRAFSQLAPLIQHQR---IHTGEKPYECNQCG 556
Query: 1640 KAQEAPS--------ETPRGPGESVERARGGQAVTSMAAEDK----ERPFRCTQCGRSYR 1687
+A S T P E + +S++ ++ E+P+ C CG+S+R
Sbjct: 557 RAFSQSSLLIEHQRIHTKEKPYGCNECGKSFSHSSSLSQHERTHTGEKPYECHDCGKSFR 616
Query: 1688 HAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHT 1727
+ L H++ HT Y C C K + SL H RTHT
Sbjct: 617 QSTHLTQHRRIHTGEKPYACRDCGKAFTHSSSLTKHQRTHT 657
Score = 57.8 bits (138), Expect = 1e-07
Identities = 31/93 (33%), Positives = 46/93 (49%), Gaps = 15/93 (16%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C + F + L++H+ + + +PY+C QCGR + L+ H+RT
Sbjct: 244 CHECLKGFRNSSALTKHQRI------------HTGEKPYKCTQCGRTFNQIAPLIQHQRT 291
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPE 100
H TG P C+ CGK FS + H RTH E
Sbjct: 292 H-TGEKPYECSECGKSFSFRSSFSQHERTHTGE 323
>gi|68303809 zinc finger protein 43 [Homo sapiens]
Length = 809
Score = 177 bits (450), Expect = 6e-44
Identities = 139/610 (22%), Positives = 236/610 (38%), Gaps = 106/610 (17%)
Query: 1203 FSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPRRFRC 1260
+ CE CG+++ + L H+ +TG + C+ C+K F+ +L H++IH + ++C
Sbjct: 258 YKCEECGKAFNKSSILTTHKII-RTGEKFYKCKECAKAFNQSSNLTEHKKIHPGEKPYKC 316
Query: 1261 SECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRS 1320
ECGKAF L H+R+H ++P+ C +CG+ + +L H+R
Sbjct: 317 EECGKAFNWPSTLTKHKRIHTG-------------EKPYTCEECGKAFNQFSNLTTHKRI 363
Query: 1321 HETGQ-YSCPTCPKTYSNRMALKDHQRLHSENR------------------RRRAGRSRR 1361
H + Y C C + +S L H+++H+E + + +
Sbjct: 364 HTAEKFYKCTECGEAFSRSSNLTKHKKIHTEKKPYKCEECGKAFKWSSKLTEHKLTHTGE 423
Query: 1362 TAVRCALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASE-ANLTGSQGLETQL 1420
+C CG++F +L +H R H T +P + + G A ++ +NLT + + T
Sbjct: 424 KPYKCEECGKAFNWPSTLTKHNRIH--TGEKPYKCE--VCGKAFNQFSNLTTHKRIHT-- 477
Query: 1421 GGAEPVPHLEDGVPRPGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVP 1480
+P E G + + + E GKA W
Sbjct: 478 -AEKPYKCEECGKAFSRSSNLTKHKKIHIEKKPYKCEECGKAFKWS-------------- 522
Query: 1481 QFLTRSEEPEDSVHRSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHS-SCSQCGKT 1539
S+ E + + C+ G +H ++ G C +CGK
Sbjct: 523 -----SKLTEHKITHTGEKPYKCEECGKAFNHFSILTKH---KRIHTGEKPYKCEECGKA 574
Query: 1540 YCQSGSLLNHNTNKTDRHY--CLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESH 1597
+ QS +L H T + C C K F +H H + + C +CGKAF
Sbjct: 575 FTQSSNLTTHKKIHTGEKFYKCEECGKAFTQSSNLTTHKKIHTGGKPYKCEECGKAFNQF 634
Query: 1598 QELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVE 1657
L H H + P + EE GKA + S +
Sbjct: 635 STLTKHKIIHTE---EKPYKCEEC-----------------GKAFKWSSTLTK------- 667
Query: 1658 RARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNL 1716
E+P++C +CG++++ + +L H+ HT Y C C K
Sbjct: 668 ---------HKIIHTGEKPYKCEECGKAFKLSSTLSTHKIIHTGEKPYKCEKCGKAFNRS 718
Query: 1717 LSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISF 1776
+L H + HT + + C CGKAF ++ L H R+H +E P+ C C + F + +
Sbjct: 719 SNLIEHKKIHTGEQPYKCEECGKAFNYSSHLNTHKRIHT-KEQPYKCKECGKAFNQYSNL 777
Query: 1777 VQHQQQHQEE 1786
H + H E
Sbjct: 778 TTHNKIHTGE 787
Score = 164 bits (416), Expect = 6e-40
Identities = 154/671 (22%), Positives = 262/671 (39%), Gaps = 132/671 (19%)
Query: 48 YRCQQCGRGYRHPGSLVNHRRTHETGLF-PCTTCGKDFSNPMALKSHMRTHAPEGRRRHR 106
++C++CG+ + L H+ H F C CGK F+ P + H R + E
Sbjct: 174 FKCKECGKSFCMLPHLAQHKIIHTRVNFCKCEKCGKAFNCPSIITKHKRINTGE------ 227
Query: 107 PPRPKEATPHLQGETVSTDSWGQRLGSSEGWENQTKHT-EETPDCESVPDPRAASGTWED 165
P+ E +W RL + + +N T++ + +C + + T +
Sbjct: 228 -------KPYTCEECGKVFNWSSRLTTHK--KNYTRYKLYKCEECGKAFNKSSILTTHKI 278
Query: 166 LPTRQREGLASHPGPEDGADGWGPSTNSAR-------APPLPIPASSLLSNLEQYLAESV 218
+ T ++ ++ A + S+N P N L +
Sbjct: 279 IRTGEKFYKC-----KECAKAFNQSSNLTEHKKIHPGEKPYKCEECGKAFNWPSTLTKHK 333
Query: 219 VNFTGGQEPTQSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSHTLG-IYPCAICFKEFSN 277
TG E+ Y C +CGK + +LT H++ HT Y C C + FS
Sbjct: 334 RIHTG------------EKPYTCEECGKAFNQFSNLTTHKRIHTAEKFYKCTECGEAFSR 381
Query: 278 LMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGM----PTT 333
L H ++H + +PY C C + F+ +L EH+ +H GE+ + EE G P+T
Sbjct: 382 SSNLTKHKKIHTEKKPYKCEECGKAFKWSSKLTEHKLTHTGEKPY-KCEECGKAFNWPST 440
Query: 334 -----NGHTDESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGS 388
HT E + N + L+T + + +P++C +CG+ + + +
Sbjct: 441 LTKHNRIHTGEKPYKCEVCGKAFNQFSNLTTHKRIHTAE----KPYKCEECGKAFSRSSN 496
Query: 389 LINHRKSH-QTGVYPCSLCSKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAPLLLAE 447
L H+K H + Y C C K ++ L H +
Sbjct: 497 LTKHKKIHIEKKPYKCEECGKAFKWSSKLTEH---------------------------K 529
Query: 448 TTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLM 505
TH E +PYKC ECG+A+ H L H+ H TGE Y+C C + +
Sbjct: 530 ITHTGE---------KPYKCEECGKAFNHFSILTKHKRIH-TGEKPYKCEECGKAFTQSS 579
Query: 506 ALRNHVRVH-------CKAARRSADIGAEGAPSHLKVELPPDPVEAEAAPHTDQDH--VC 556
L H ++H C+ + A + +H K+ P + E +
Sbjct: 580 NLTTHKKIHTGEKFYKCEECGK-AFTQSSNLTTHKKIHTGGKPYKCEECGKAFNQFSTLT 638
Query: 557 KHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTE-------- 608
KH+ T+ P + C CG F+ + +L +H + H GEK E
Sbjct: 639 KHKIIHTEEKP-------YKCEECGKAFKWSSTLTKHKIIH-TGEKPYKCEECGKAFKLS 690
Query: 609 TTMSP-------PRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAM 659
+T+S + + C CGK++ S +LI H++ H TG+ + C C K F+ + +
Sbjct: 691 STLSTHKIIHTGEKPYKCEKCGKAFNRSSNLIEHKKIH-TGEQPYKCEECGKAFNYSSHL 749
Query: 660 KNHLRRHSRRR 670
H R H++ +
Sbjct: 750 NTHKRIHTKEQ 760
Score = 157 bits (398), Expect = 7e-38
Identities = 135/533 (25%), Positives = 214/533 (40%), Gaps = 88/533 (16%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C + F L+ H+++ HP +PY+C++CG+ + P +L H+R
Sbjct: 288 CKECAKAFNQSSNLTEHKKI-HPGE-----------KPYKCEECGKAFNWPSTLTKHKRI 335
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPEGRRR-----HRPPRPKEATPHLQGETV 122
H TG P C CGK F+ L +H R H E + R T H + T
Sbjct: 336 H-TGEKPYTCEECGKAFNQFSNLTTHKRIHTAEKFYKCTECGEAFSRSSNLTKHKKIHTE 394
Query: 123 STDSWGQRLGSSEGW-----ENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQREGLAS 176
+ G + W E++ HT E P CE + W T+
Sbjct: 395 KKPYKCEECGKAFKWSSKLTEHKLTHTGEKPYKCEEC----GKAFNWPSTLTKHNR---I 447
Query: 177 HPGPED-GADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVN-------FTGGQEPT 228
H G + + G + N S+L ++ + AE F+ T
Sbjct: 448 HTGEKPYKCEVCGKAFNQ---------FSNLTTHKRIHTAEKPYKCEECGKAFSRSSNLT 498
Query: 229 QSPPAE-EERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSR 286
+ E++ YKC +CGK +K + LT H+ +HT Y C C K F++ L H R
Sbjct: 499 KHKKIHIEKKPYKCEECGKAFKWSSKLTEHKITHTGEKPYKCEECGKAFNHFSILTKHKR 558
Query: 287 LHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLP 346
+H +PY C C + F L H++ H GE+ + EE G T
Sbjct: 559 IHTGEKPYKCEECGKAFTQSSNLTTHKKIHTGEKFY-KCEECGKAFTQ------------ 605
Query: 347 SAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSH-QTGVYPCSL 405
S+ L+T ++ G +P++C +CG+ + +L H+ H + Y C
Sbjct: 606 -------SSNLTTHKKIHTGG----KPYKCEECGKAFNQFSTLTKHKIIHTEEKPYKCEE 654
Query: 406 CSKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPY 465
C K ++ L H H + E + + L +THK +PY
Sbjct: 655 CGKAFKWSSTLTKHKIIHTGEKPYKCEECGKAFKLSSTL---STHK-----IIHTGEKPY 706
Query: 466 KCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHCK 516
KC +CG+A+ +L+ H+ H TGE Y+C C + + L H R+H K
Sbjct: 707 KCEKCGKAFNRSSNLIEHKKIH-TGEQPYKCEECGKAFNYSSHLNTHKRIHTK 758
Score = 150 bits (378), Expect = 1e-35
Identities = 158/682 (23%), Positives = 258/682 (37%), Gaps = 124/682 (18%)
Query: 10 CSDCQRHFPSLPELSRHRELLH-----------------PSPNQDSEEADSIPRPYRCQQ 52
C +C + F LP L++H+ ++H PS + ++ +PY C++
Sbjct: 176 CKECGKSFCMLPHLAQHK-IIHTRVNFCKCEKCGKAFNCPSIITKHKRINTGEKPYTCEE 234
Query: 53 CGRGYRHPGSLVNHRRTH-ETGLFPCTTCGKDFSNPMALKSH--MRT------------- 96
CG+ + L H++ + L+ C CGK F+ L +H +RT
Sbjct: 235 CGKVFNWSSRLTTHKKNYTRYKLYKCEECGKAFNKSSILTTHKIIRTGEKFYKCKECAKA 294
Query: 97 -HAPEGRRRHRPPRPKEATPHLQGETVSTDSWGQRLGSSEGWENQTKHTEETP-DCESVP 154
+ H+ P E P+ E +W L +++ HT E P CE
Sbjct: 295 FNQSSNLTEHKKIHPGE-KPYKCEECGKAFNWPSTL-----TKHKRIHTGEKPYTCE--- 345
Query: 155 DPRAASGTWEDLPTRQREGLAS--HPGPEDGADGWGPSTNSAR-------APPLPIPASS 205
+ A + +L T +R A + E G + + S+N + P
Sbjct: 346 ECGKAFNQFSNLTTHKRIHTAEKFYKCTECG-EAFSRSSNLTKHKKIHTEKKPYKCEECG 404
Query: 206 LLSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSHT-LG 264
L E + TG E+ YKC +CGK + +LT H + HT
Sbjct: 405 KAFKWSSKLTEHKLTHTG------------EKPYKCEECGKAFNWPSTLTKHNRIHTGEK 452
Query: 265 IYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGER---- 320
Y C +C K F+ L H R+H +PY C C + F L +H++ H ++
Sbjct: 453 PYKCEVCGKAFNQFSNLTTHKRIHTAEKPYKCEECGKAFSRSSNLTKHKKIHIEKKPYKC 512
Query: 321 ----QEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRC 376
+ +W K HT E + N + L+ + +P++C
Sbjct: 513 EECGKAFKWSSKLTEHKITHTGEKPYKCEECGKAFNHFSILTKHKRIHTG----EKPYKC 568
Query: 377 GDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFNAAALKNHVRAHHRPR-QGVGEN 433
+CG+ + + +L H+K H TG Y C C K ++ L H + H + E
Sbjct: 569 EECGKAFTQSSNLTTHKKIH-TGEKFYKCEECGKAFTQSSNLTTHKKIHTGGKPYKCEEC 627
Query: 434 GQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE-- 491
G+ + L + H EE +PYKC ECG+A++ +L H+ H TGE
Sbjct: 628 GKAFNQFSTLTKHKIIHTEE---------KPYKCEECGKAFKWSSTLTKHKIIH-TGEKP 677
Query: 492 YQCSLCPRKYPNLMALRNHVRVHC-----------KAARRSADIGAEGAPSHLKVELPPD 540
Y+C C + + L H +H KA RS+++ H K+
Sbjct: 678 YKCEECGKAFKLSSTLSTHKIIHTGEKPYKCEKCGKAFNRSSNL-----IEHKKIHTGEQ 732
Query: 541 PVEAE--AAPHTDQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHG 598
P + E H+ H+ T K + C CG F +L H H
Sbjct: 733 PYKCEECGKAFNYSSHLNTHKRIHT-------KEQPYKCKECGKAFNQYSNLTTHNKIH- 784
Query: 599 AGEKENSRTETT--MSPPRAFA 618
GEK + T ++ P+ F+
Sbjct: 785 TGEKLYKPEDVTVILTTPQTFS 806
Score = 149 bits (376), Expect = 2e-35
Identities = 140/634 (22%), Positives = 238/634 (37%), Gaps = 86/634 (13%)
Query: 1197 ASSERPFSCEVCGRSYKHAGSLINHRQSH-QTGHFGCQACSKGFSNLMSLKNHRRIHADP 1255
A+ + F + C +++ + H+ SH + F C+ C K F L L H+ IH
Sbjct: 140 ATQSKIFLFDKCVKAFHKFSNSNRHKISHTEKKLFKCKECGKSFCMLPHLAQHKIIHTRV 199
Query: 1256 RRFRCSECGKAFRLRKQLASHQRVHMERRG----------GGGTRKATRED-----RPFR 1300
+C +CGKAF + H+R++ + +R T + + ++
Sbjct: 200 NFCKCEKCGKAFNCPSIITKHKRINTGEKPYTCEECGKVFNWSSRLTTHKKNYTRYKLYK 259
Query: 1301 CGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGR 1358
C +CG+ + + L H + TG+ Y C C K ++ L +H+++H +
Sbjct: 260 CEECGKAFNKSSILTTH-KIIRTGEKFYKCKECAKAFNQSSNLTEHKKIHPGEK------ 312
Query: 1359 SRRTAVRCALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASE-ANLTGSQGLE 1417
+C CG++F +L +H R H T +P + G A ++ +NLT + +
Sbjct: 313 ----PYKCEECGKAFNWPSTLTKHKRIH--TGEKPYTCEE--CGKAFNQFSNLTTHKRIH 364
Query: 1418 TQLGGAEPVPHLEDGVPRPGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGG 1477
T + E G + + + +E GKA W L H
Sbjct: 365 T---AEKFYKCTECGEAFSRSSNLTKHKKIHTEKKPYKCEECGKAFKW--SSKLTEHKLT 419
Query: 1478 WVPQFLTRSEE-------PEDSVHRSPCHAGD----CQLNGPTLSHMDSWDNRDNSSQLQ 1526
+ + EE P + H G+ C++ G + + +
Sbjct: 420 HTGEKPYKCEECGKAFNWPSTLTKHNRIHTGEKPYKCEVCGKAFNQFSNLTTHKRIHTAE 479
Query: 1527 PGSHSSCSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQT 1584
C +CGK + +S +L H ++ + C C K F H H +
Sbjct: 480 --KPYKCEECGKAFSRSSNLTKHKKIHIEKKPYKCEECGKAFKWSSKLTEHKITHTGEKP 537
Query: 1585 FACPDCGKAFESHQELASHLQAHARGHSQVPAQMEE-----------ARDPKAGTGEDQV 1633
+ C +CGKAF L H + H + P + EE K TGE
Sbjct: 538 YKCEECGKAFNHFSILTKHKRIHT---GEKPYKCEECGKAFTQSSNLTTHKKIHTGEKFY 594
Query: 1634 VLPGQGKAQEAPSETPRGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLL 1693
GKA + T +P++C +CG+++ +L
Sbjct: 595 KCEECGKA----------------FTQSSNLTTHKKIHTGGKPYKCEECGKAFNQFSTLT 638
Query: 1694 NHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGR 1752
H+ HT Y C C K +L H HT K + C CGKAF+ ++ L H
Sbjct: 639 KHKIIHTEEKPYKCEECGKAFKWSSTLTKHKIIHTGEKPYKCEECGKAFKLSSTLSTHKI 698
Query: 1753 VHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
+H E P+ C C + F R + ++H++ H E
Sbjct: 699 IHT-GEKPYKCEKCGKAFNRSSNLIEHKKIHTGE 731
Score = 142 bits (359), Expect = 2e-33
Identities = 121/593 (20%), Positives = 226/593 (38%), Gaps = 121/593 (20%)
Query: 821 HTCSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQ 879
+ C +C +F ++ L H+ HP Y+C C K F+ L H + H T +
Sbjct: 286 YKCKECAKAFNQSSNLTEHKKIHPGEKPYKCEECGKAFNWPSTLTKHKRIH-----TGEK 340
Query: 880 PFLCCLCGMIFPGRAGYRLHRR--------------QAHS-SSGMTEGSEEEGEEEGVA- 923
P+ C CG F + H+R +A S SS +T+ + E++
Sbjct: 341 PYTCEECGKAFNQFSNLTTHKRIHTAEKFYKCTECGEAFSRSSNLTKHKKIHTEKKPYKC 400
Query: 924 -EAAPARSPPLQLSEAELLNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSS 982
E A +L+E +L + ++ + C CG+ ++ +L +H++ +
Sbjct: 401 EECGKAFKWSSKLTEHKLTHTGEKPYK----------CEECGKAFNWPSTLTKHNRIHTG 450
Query: 983 GTTADKAPSPLGVAGDAMEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGE 1042
+ P V G A + +++
Sbjct: 451 -----EKPYKCEVCGKAFNQFSNLTTHKRIHTAE-------------------------- 479
Query: 1043 SLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIH-QTGDFLCPVCSRCYPNLAAYRNHLRNH 1101
+P++C +CGK + +L H+KIH + + C C + + + H H
Sbjct: 480 -------KPYKCEECGKAFSRSSNLTKHKKIHIEKKPYKCEECGKAFKWSSKLTEHKITH 532
Query: 1102 P-----RCKGSEPQVGPIPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEEL 1156
+C+ + G KP E G + L
Sbjct: 533 TGEKPYKCEECGKAFNHFSILTKHKRIHTG-------EKPYKCEECGKAFTQSSNLTTHK 585
Query: 1157 KVEPLEEVARVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAG 1216
K+ E+ + +E T ++ T K P+ CE CG+++
Sbjct: 586 KIHTGEKFYKCEECGKAFTQSSNLTTHKKIHTGGK----------PYKCEECGKAFNQFS 635
Query: 1217 SLINHRQSH-QTGHFGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLAS 1275
+L H+ H + + C+ C K F +L H+ IH + ++C ECGKAF+L L++
Sbjct: 636 TLTKHKIIHTEEKPYKCEECGKAFKWSSTLTKHKIIHTGEKPYKCEECGKAFKLSSTLST 695
Query: 1276 HQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPK 1333
H+ +H ++P++C +CG+ + + +L+ H++ H TG+ Y C C K
Sbjct: 696 HKIIH-------------TGEKPYKCEKCGKAFNRSSNLIEHKKIH-TGEQPYKCEECGK 741
Query: 1334 TYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREH 1386
++ L H+R+H++ + +C CG++F +L H + H
Sbjct: 742 AFNYSSHLNTHKRIHTKEQ----------PYKCKECGKAFNQYSNLTTHNKIH 784
Score = 140 bits (353), Expect = 1e-32
Identities = 130/585 (22%), Positives = 233/585 (39%), Gaps = 93/585 (15%)
Query: 821 HTCSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQ 879
+ C +CG +F ++ L +H+ Y+C C K F+ L H + H PGE +
Sbjct: 258 YKCEECGKAFNKSSILTTHKIIRTGEKFYKCKECAKAFNQSSNLTEHKKIH-PGE----K 312
Query: 880 PFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAE 939
P+ C CG F + H+R H+ GE+ E +
Sbjct: 313 PYKCEECGKAFNWPSTLTKHKR-IHT-----------GEKPYTCEEC-----------GK 349
Query: 940 LLNQLQREV--EALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAG 997
NQ + + +A + C CG+ + +L +H + + +K P G
Sbjct: 350 AFNQFSNLTTHKRIHTAEKFYKCTECGEAFSRSSNLTKHKKIHT-----EKKPYKCEECG 404
Query: 998 DAMEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQC 1057
A + S L + + +GE + G +L + + +P++C C
Sbjct: 405 KAFKW--SSKLTEHKLTHTGEKPYKCEECGKAFNWPSTLT---KHNRIHTGEKPYKCEVC 459
Query: 1058 GKTYRHGGSLVNHRKIHQTGD-FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPE 1116
GK + +L H++IH + C C + + + H + H K + E
Sbjct: 460 GKAFNQFSNLTTHKRIHTAEKPYKCEECGKAFSRSSNLTKHKKIHIEKKPYKC------E 513
Query: 1117 AAG-----SSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKEEV 1171
G SS+L I G KP E G L + ++ E+ + +E
Sbjct: 514 ECGKAFKWSSKLTEHKITHTGE-KPYKCEECGKAFNHFSILTKHKRIHTGEKPYKCEECG 572
Query: 1172 WEETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH-F 1230
T ++ T EK + CE CG+++ + +L H++ H G +
Sbjct: 573 KAFTQSSNLTTHKKIHTGEKF----------YKCEECGKAFTQSSNLTTHKKIHTGGKPY 622
Query: 1231 GCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTR 1290
C+ C K F+ +L H+ IH + + ++C ECGKAF+ L H+ +H
Sbjct: 623 KCEECGKAFNQFSTLTKHKIIHTEEKPYKCEECGKAFKWSSTLTKHKIIHTG-------- 674
Query: 1291 KATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLH 1348
++P++C +CG+ ++ + +L H+ H TG+ Y C C K ++ L +H+++H
Sbjct: 675 -----EKPYKCEECGKAFKLSSTLSTHKIIH-TGEKPYKCEKCGKAFNRSSNLIEHKKIH 728
Query: 1349 SENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHEETEREP 1393
+ + +C CG++F L H R H T+ +P
Sbjct: 729 TGEQ----------PYKCEECGKAFNYSSHLNTHKRIH--TKEQP 761
Score = 136 bits (342), Expect = 2e-31
Identities = 129/592 (21%), Positives = 235/592 (39%), Gaps = 119/592 (20%)
Query: 821 HTCSDCGHSFPHATGLLSHRPCHPP-GIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQ 879
+TC +CG F ++ L +H+ + +Y+C C K F+ L +H + R GE +
Sbjct: 230 YTCEECGKVFNWSSRLTTHKKNYTRYKLYKCEECGKAFNKSSILTTH-KIIRTGE----K 284
Query: 880 PFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEE--GVAEAAPARSPPLQLSE 937
+ C C F + SS +TE + E+ E A + P L++
Sbjct: 285 FYKCKECAKAF-------------NQSSNLTEHKKIHPGEKPYKCEECGKAFNWPSTLTK 331
Query: 938 AELLNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAG 997
+ ++ ++ + C CG+ ++ +L H + TA+K G
Sbjct: 332 HKRIHTGEKP----------YTCEECGKAFNQFSNLTTHKRIH----TAEKF-YKCTECG 376
Query: 998 DAMEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQC 1057
+A + +++ E K +E S + L +P++C +C
Sbjct: 377 EAFSRSSNLTKHKKIHT---EKKPYKCEECGKAFKWSSKLTE--HKLTHTGEKPYKCEEC 431
Query: 1058 GKTYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIP 1115
GK + +L H +IH TG+ + C VC + + + H R H
Sbjct: 432 GKAFNWPSTLTKHNRIH-TGEKPYKCEVCGKAFNQFSNLTTHKRIHT------------- 477
Query: 1116 EAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKEEVWEET 1175
+ KP E G + L + K+ E+
Sbjct: 478 -----------------AEKPYKCEECGKAFSRSSNLTKHKKIH------------IEKK 508
Query: 1176 TVKGEEIEPRLETAEKGCQTEA--SSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FG 1231
K EE + + K + + + E+P+ CE CG+++ H L H++ H TG +
Sbjct: 509 PYKCEECGKAFKWSSKLTEHKITHTGEKPYKCEECGKAFNHFSILTKHKRIH-TGEKPYK 567
Query: 1232 CQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVH-------MERR 1284
C+ C K F+ +L H++IH + ++C ECGKAF L +H+++H E
Sbjct: 568 CEECGKAFTQSSNLTTHKKIHTGEKFYKCEECGKAFTQSSNLTTHKKIHTGGKPYKCEEC 627
Query: 1285 GGGGTRKAT--------REDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKT 1334
G + +T E++P++C +CG+ ++ + +L H+ H TG+ Y C C K
Sbjct: 628 GKAFNQFSTLTKHKIIHTEEKPYKCEECGKAFKWSSTLTKHKIIH-TGEKPYKCEECGKA 686
Query: 1335 YSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREH 1386
+ L H+ +H+ + +C CG++F +L H + H
Sbjct: 687 FKLSSTLSTHKIIHTGEK----------PYKCEKCGKAFNRSSNLIEHKKIH 728
Score = 134 bits (336), Expect = 1e-30
Identities = 120/533 (22%), Positives = 214/533 (40%), Gaps = 83/533 (15%)
Query: 821 HTCSDCGHSFPHATGLLSHRPCHPPG-IYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQ 879
+TC +CG +F + L +H+ H Y+C+ C + F L H + H T +
Sbjct: 342 YTCEECGKAFNQFSNLTTHKRIHTAEKFYKCTECGEAFSRSSNLTKHKKIH-----TEKK 396
Query: 880 PFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAE 939
P+ C CG F + H+ +T E+ + E E A + P L++
Sbjct: 397 PYKCEECGKAFKWSSKLTEHK--------LTHTGEKPYKCE---ECGKAFNWPSTLTKHN 445
Query: 940 LLNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDA 999
++ ++ + C CG+ ++ +L H + TA+K P G A
Sbjct: 446 RIHTGEKPYK----------CEVCGKAFNQFSNLTTHKRIH----TAEK-PYKCEECGKA 490
Query: 1000 MEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGK 1059
+ ++ E K +E S + + +P++C +CGK
Sbjct: 491 FSRSSNLTKHKKIHI---EKKPYKCEECGKAFKWSSKLTE--HKITHTGEKPYKCEECGK 545
Query: 1060 TYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEA 1117
+ H L H++IH TG+ + C C + + + H + H K + +
Sbjct: 546 AFNHFSILTKHKRIH-TGEKPYKCEECGKAFTQSSNLTTHKKIHTGEKFYKCEECGKAFT 604
Query: 1118 AGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKE----EVWE 1173
S+ I GG KP E G + L + + E+ + +E W
Sbjct: 605 QSSNLTTHKKIHTGG--KPYKCEECGKAFNQFSTLTKHKIIHTEEKPYKCEECGKAFKWS 662
Query: 1174 ETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FG 1231
T K + I + E+P+ CE CG+++K + +L H+ H TG +
Sbjct: 663 STLTKHKIIH--------------TGEKPYKCEECGKAFKLSSTLSTHKIIH-TGEKPYK 707
Query: 1232 CQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRK 1291
C+ C K F+ +L H++IH + ++C ECGKAF L +H+R+H
Sbjct: 708 CEKCGKAFNRSSNLIEHKKIHTGEQPYKCEECGKAFNYSSHLNTHKRIH----------- 756
Query: 1292 ATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQYSCP-------TCPKTYSN 1337
+++P++C +CG+ + +L H + H + P T P+T+SN
Sbjct: 757 --TKEQPYKCKECGKAFNQYSNLTTHNKIHTGEKLYKPEDVTVILTTPQTFSN 807
Score = 127 bits (319), Expect = 1e-28
Identities = 111/487 (22%), Positives = 191/487 (39%), Gaps = 81/487 (16%)
Query: 229 QSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRL 287
Q PA + + + +C K + + H+ SHT ++ C C K F L L H +
Sbjct: 136 QCLPATQSKIFLFDKCVKAFHKFSNSNRHKISHTEKKLFKCKECGKSFCMLPHLAQHKII 195
Query: 288 HAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQEP--------RWEEKGMPTTNGHTDE 339
H + C C + F P + +H++ + GE+ W + +T
Sbjct: 196 HTRVNFCKCEKCGKAFNCPSIITKHKRINTGEKPYTCEECGKVFNWSSRLTTHKKNYTRY 255
Query: 340 SSQDQLPSAQMLNGSAELST-----SGEL------------EDSGLEEY-------RPFR 375
+ N S+ L+T +GE + S L E+ +P++
Sbjct: 256 KLYKCEECGKAFNKSSILTTHKIIRTGEKFYKCKECAKAFNQSSNLTEHKKIHPGEKPYK 315
Query: 376 CGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFNAAALKNHVRAHHRPR-QGVGE 432
C +CG+ + +L H++ H TG Y C C K + L H R H + E
Sbjct: 316 CEECGKAFNWPSTLTKHKRIH-TGEKPYTCEECGKAFNQFSNLTTHKRIHTAEKFYKCTE 374
Query: 433 NGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE- 491
G+ + L + H E+ +PYKC ECG+A++ L H+ +H TGE
Sbjct: 375 CGEAFSRSSNLTKHKKIHTEK---------KPYKCEECGKAFKWSSKLTEHKLTH-TGEK 424
Query: 492 -YQCSLCPRKYPNLMALRNHVRVHCKAARRSADIGAE------GAPSHLKVELPPDPVEA 544
Y+C C + + L H R+H ++ + +H ++ P +
Sbjct: 425 PYKCEECGKAFNWPSTLTKHNRIHTGEKPYKCEVCGKAFNQFSNLTTHKRIHTAEKPYKC 484
Query: 545 E--AAPHTDQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEK 602
E + ++ KH++ + P + C CG F+ + L H +TH GEK
Sbjct: 485 EECGKAFSRSSNLTKHKKIHIEKKP-------YKCEECGKAFKWSSKLTEHKITH-TGEK 536
Query: 603 ENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMK 660
+ C +CGK++ H L H++ H TG+ + C C K F + +
Sbjct: 537 -------------PYKCEECGKAFNHFSILTKHKRIH-TGEKPYKCEECGKAFTQSSNLT 582
Query: 661 NHLRRHS 667
H + H+
Sbjct: 583 THKKIHT 589
Score = 104 bits (259), Expect = 9e-22
Identities = 56/213 (26%), Positives = 101/213 (47%), Gaps = 32/213 (15%)
Query: 1184 PRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH-FGCQACSKGFSNL 1242
P + T K T E+P++CE CG+ + + L H++++ + C+ C K F+
Sbjct: 214 PSIITKHKRINT---GEKPYTCEECGKVFNWSSRLTTHKKNYTRYKLYKCEECGKAFNKS 270
Query: 1243 MSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCG 1302
L H+ I + ++C EC KAF L H+++H ++P++C
Sbjct: 271 SILTTHKIIRTGEKFYKCKECAKAFNQSSNLTEHKKIHPG-------------EKPYKCE 317
Query: 1303 QCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSR 1360
+CG+ + +L H+R H TG+ Y+C C K ++ L H+R+H+ +
Sbjct: 318 ECGKAFNWPSTLTKHKRIH-TGEKPYTCEECGKAFNQFSNLTTHKRIHTAEK-------- 368
Query: 1361 RTAVRCALCGRSFPGRGSLERHLREHEETEREP 1393
+C CG +F +L +H + H TE++P
Sbjct: 369 --FYKCTECGEAFSRSSNLTKHKKIH--TEKKP 397
>gi|154800449 zinc finger protein 132 [Homo sapiens]
Length = 706
Score = 173 bits (438), Expect = 2e-42
Identities = 163/660 (24%), Positives = 263/660 (39%), Gaps = 103/660 (15%)
Query: 34 PNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRTH-ETGLFPCTTCGKDFSNPMALKS 92
PN D S + C CG + L H+ T E + C CG+DF L
Sbjct: 104 PNADP----STKKANSCDMCGPFLKDILHLAEHQGTQSEEKPYTCGACGRDFWLNANLHQ 159
Query: 93 HMRTHA---PEGRRRHRPPRPKEATPHLQGETVSTDSWGQR-LGSSEGWENQTKHTEETP 148
H + H+ P + R K + HL + G+ LGS + + Q
Sbjct: 160 HQKEHSGGKPFRWYKDRDALMKSSKVHLSENPFTCREGGKVILGSCDLLQLQA------- 212
Query: 149 DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGADGWGPSTNSARAPPLPIPASSLLS 208
+S P + G ++ T Q+ S+ G P+ + +P + +
Sbjct: 213 -VDSGQKPYSNLGQLPEVCTTQKLFECSNCGKAFLKSSTLPNHLRTHSEEIPFTCPTGGN 271
Query: 209 NLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYP 267
LE+ F G+ P + C +CGK + H+ L H++ HT + Y
Sbjct: 272 FLEEKSILGNKKFHTGEIP-----------HVCKECGKAFSHSSKLRKHQKFHTEVKYYE 320
Query: 268 CAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEE 327
C C K F++ + +H R+H+ RPY C C + F L+ H++ H GER
Sbjct: 321 CIACGKTFNHKLTFVHHQRIHSGERPYECDECGKAFSNRSHLIRHEKVHTGER------- 373
Query: 328 KGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSGELEDSGLE-EYRPFRCGDCGRTYRHA 386
P + G A +S L + + RP+ C CG+++ +
Sbjct: 374 ------------------PFECLKCGRAFSQSSNFLRHQKVHTQVRPYECSQCGKSFSRS 415
Query: 387 GSLINHRKSHQTGV--YPCSLCSKQLFNAAALKNHVRAH--HRPRQGVGENGQPSVPPAP 442
+LI H + H TG Y CS C + N + L H + H RP + E G+ +
Sbjct: 416 SALIQHWRVH-TGERPYECSECGRAFNNNSNLAQHQKVHTGERPFE-CSECGRDFSQSSH 473
Query: 443 LLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRK 500
LL + H E RP++C +CG+A+ + +L+ H+ H TG+ Y+CS C +
Sbjct: 474 LLRHQKVHTGE---------RPFECCDCGKAFSNSSTLIQHQKVH-TGQRPYECSECRKS 523
Query: 501 YPNLMALRNHVRVHC-KAARRSADIGAEGAPS-----HLKVELPPDPVEA-EAAPHTDQD 553
+ +L H R+H + ++ G A S H +V P E E Q+
Sbjct: 524 FSRSSSLIQHWRIHTGEKPYECSECGKAFAHSSTLIEHWRVHTKERPYECNECGKFFSQN 583
Query: 554 HVC-KHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTETTMS 612
+ KH++ T P + CS CG F SL H H GE
Sbjct: 584 SILIKHQKVHTGEKP-------YKCSECGKFFSRKSSLICHWRVH-TGE----------- 624
Query: 613 PPRAFACRDCGKSYRHSGSLINHRQTH-QTGDFSCGACAKHFHTMAAMKNHLRRHSRRRS 671
R + C +CG+++ + L+ H++ H Q + C C K F + + H + H+R R+
Sbjct: 625 --RPYECSECGRAFSSNSHLVRHQRVHTQERPYECIQCGKAFSERSTLVRHQKVHTRERT 682
Score = 157 bits (398), Expect = 7e-38
Identities = 148/633 (23%), Positives = 220/633 (34%), Gaps = 132/633 (20%)
Query: 1194 QTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH-----------------------F 1230
Q S E+P++C CGR + +L H++ H G F
Sbjct: 133 QGTQSEEKPYTCGACGRDFWLNANLHQHQKEHSGGKPFRWYKDRDALMKSSKVHLSENPF 192
Query: 1231 GC----------------QACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLA 1274
C QA G +L + + F CS CGKAF L
Sbjct: 193 TCREGGKVILGSCDLLQLQAVDSGQKPYSNLGQLPEVCTTQKLFECSNCGKAFLKSSTLP 252
Query: 1275 SHQRVHMER------RGGG--------GTRKATREDRPFRCGQCGRTYRHAGSLLNHRRS 1320
+H R H E GG G +K + P C +CG+ + H+ L H++
Sbjct: 253 NHLRTHSEEIPFTCPTGGNFLEEKSILGNKKFHTGEIPHVCKECGKAFSHSSKLRKHQKF 312
Query: 1321 H-ETGQYSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSL 1379
H E Y C C KT+++++ HQR+HS R C CG++F R L
Sbjct: 313 HTEVKYYECIACGKTFNHKLTFVHHQRIHSGER----------PYECDECGKAFSNRSHL 362
Query: 1380 ERHLREHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRPGER 1439
RH + H G+ + A S L Q + P+ + R
Sbjct: 363 IRHEKVH--------TGERPFECLKCGRAFSQSSNFLRHQKVHTQVRPYECSQCGKSFSR 414
Query: 1440 SQSPI---RAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRS 1496
S + I R + E P S G N+S Q + E P +
Sbjct: 415 SSALIQHWRVHTGERPYECS---------ECGRAFNNNSNLAQHQKVHTGERPFE----- 460
Query: 1497 PCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHS-SCSQCGKTYCQSGSLLNHNTNKTD 1555
+C + SH+ ++ G C CGK + S +L+ H T
Sbjct: 461 ---CSECGRDFSQSSHLL------RHQKVHTGERPFECCDCGKAFSNSSTLIQHQKVHTG 511
Query: 1556 R--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQ 1613
+ + C C K F + H H + + C +CGKAF L H + H + +
Sbjct: 512 QRPYECSECRKSFSRSSSLIQHWRIHTGEKPYECSECGKAFAHSSTLIEHWRVHTK---E 568
Query: 1614 VPAQMEEA-----------RDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVERARGG 1662
P + E + K TGE GK +R
Sbjct: 569 RPYECNECGKFFSQNSILIKHQKVHTGEKPYKCSECGKFF----------------SRKS 612
Query: 1663 QAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKN 1721
+ ERP+ C++CGR++ L+ HQ+ HT Y C C K +L
Sbjct: 613 SLICHWRVHTGERPYECSECGRAFSSNSHLVRHQRVHTQERPYECIQCGKAFSERSTLVR 672
Query: 1722 HSRTHTDPKRHCCSICGKAFRTAARLEGHGRVH 1754
H + HT + + CS CGK F L H ++H
Sbjct: 673 HQKVHTRERTYECSQCGKLFSHLCNLAQHKKIH 705
Score = 157 bits (397), Expect = 9e-38
Identities = 169/683 (24%), Positives = 271/683 (39%), Gaps = 140/683 (20%)
Query: 1046 EAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGDFLCPVCSRCYPN----LAAYRNHLRNH 1101
+++ +P+ C CG+ + +L H+K H G R Y + + + + HL +
Sbjct: 136 QSEEKPYTCGACGRDFWLNANLHQHQKEHSGGKPF-----RWYKDRDALMKSSKVHLSEN 190
Query: 1102 P-RCKGSEPQVGPIPEAAGSSE-LQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQE----- 1154
P C+ + GS + LQ+ + G KP + P +KL E
Sbjct: 191 PFTCREGGKVI------LGSCDLLQLQAVDSG--QKPYSNLGQLPEVCTTQKLFECSNCG 242
Query: 1155 --ELKVEPLEEVARV-KEEVWEETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRS 1211
LK L R EE+ G +E + K T E P C+ CG++
Sbjct: 243 KAFLKSSTLPNHLRTHSEEIPFTCPTGGNFLEEKSILGNKKFHT---GEIPHVCKECGKA 299
Query: 1212 YKHAGSLINHRQSH-QTGHFGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLR 1270
+ H+ L H++ H + ++ C AC K F++ ++ +H+RIH+ R + C ECGKAF R
Sbjct: 300 FSHSSKLRKHQKFHTEVKYYECIACGKTFNHKLTFVHHQRIHSGERPYECDECGKAFSNR 359
Query: 1271 KQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRSH-ETGQYSCP 1329
L H++VH +RPF C +CGR + + + L H++ H + Y C
Sbjct: 360 SHLIRHEKVH-------------TGERPFECLKCGRAFSQSSNFLRHQKVHTQVRPYECS 406
Query: 1330 TCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHEET 1389
C K++S AL H R+H+ R C+ CGR+F +L +H + H
Sbjct: 407 QCGKSFSRSSALIQHWRVHTGER----------PYECSECGRAFNNNSNLAQHQKVH-TG 455
Query: 1390 EREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVP----------RPGER 1439
ER + G D + +S +L Q + T G P + G +
Sbjct: 456 ERPFECSECGRDFSQSS--HLLRHQKVHT---GERPFECCDCGKAFSNSSTLIQHQKVHT 510
Query: 1440 SQSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSPCH 1499
Q P SE + S + W + H+G E+P + S C
Sbjct: 511 GQRPYEC--SECRKSFSRSSSLIQHWRI------HTG----------EKPYEC---SEC- 548
Query: 1500 AGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHSSCSQCGKTYCQSGSLLNHNTNKTDR--H 1557
G + TL ++ W R ++ + +P + C GK + Q+ L+ H T +
Sbjct: 549 -GKAFAHSSTL--IEHW--RVHTKE-RPYECNEC---GKFFSQNSILIKHQKVHTGEKPY 599
Query: 1558 YCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQVPAQ 1617
C C K F + H H + + C +CG+AF S+ SHL H R H+
Sbjct: 600 KCSECGKFFSRKSSLICHWRVHTGERPYECSECGRAFSSN----SHLVRHQRVHT----- 650
Query: 1618 MEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVERARGGQAVTSMAAEDKERPF 1677
QE P E + ER+ V +ER +
Sbjct: 651 ------------------------QERPYECIQCGKAFSERS---TLVRHQKVHTRERTY 683
Query: 1678 RCTQCGRSYRHAGSLLNHQKAHT 1700
C+QCG+ + H +L H+K HT
Sbjct: 684 ECSQCGKLFSHLCNLAQHKKIHT 706
Score = 149 bits (376), Expect = 2e-35
Identities = 115/411 (27%), Positives = 173/411 (42%), Gaps = 84/411 (20%)
Query: 236 ERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPY 294
ER ++C +CG+ + + + H++ HT + Y C+ C K FS AL H R+H RPY
Sbjct: 372 ERPFECLKCGRAFSQSSNFLRHQKVHTQVRPYECSQCGKSFSRSSALIQHWRVHTGERPY 431
Query: 295 HCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGS 354
C C R F L +HQ+ H GER E +D S+ +L
Sbjct: 432 ECSECGRAFNNNSNLAQHQKVHTGERP-------------FECSECGRDFSQSSHLLR-- 476
Query: 355 AELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFN 412
+ +GE RPF C DCG+ + ++ +LI H+K H TG Y CS C K
Sbjct: 477 HQKVHTGE---------RPFECCDCGKAFSNSSTLIQHQKVH-TGQRPYECSECRKSFSR 526
Query: 413 AAALKNHVRAH--HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSEC 470
+++L H R H +P + E G+ + L+ H +E RPY+C+EC
Sbjct: 527 SSSLIQHWRIHTGEKPYE-CSECGKAFAHSSTLIEHWRVHTKE---------RPYECNEC 576
Query: 471 GRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHCKAARRSADIGAEG 528
G+ + L+ H+ H TGE Y+CS C + + +L H RVH
Sbjct: 577 GKFFSQNSILIKHQKVH-TGEKPYKCSECGKFFSRKSSLICHWRVHTG------------ 623
Query: 529 APSHLKVELPPDPVEAEAAPHTDQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAE 588
E P + E A + H+ +H+ T P + C CG F +
Sbjct: 624 -------ERPYECSECGRA-FSSNSHLVRHQRVHTQERP-------YECIQCGKAFSERS 668
Query: 589 SLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTH 639
+L RH H + R + C CGK + H +L H++ H
Sbjct: 669 TLVRHQKVH--------------TRERTYECSQCGKLFSHLCNLAQHKKIH 705
Score = 142 bits (358), Expect = 3e-33
Identities = 134/515 (26%), Positives = 198/515 (38%), Gaps = 112/515 (21%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C + F +L +H++ + + Y C CG+ + H + V+H+R
Sbjct: 293 CKECGKAFSHSSKLRKHQKF------------HTEVKYYECIACGKTFNHKLTFVHHQRI 340
Query: 70 HE-TGLFPCTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHLQGETVSTDSWG 128
H + C CGK FSN L H + H E RP E G S
Sbjct: 341 HSGERPYECDECGKAFSNRSHLIRHEKVHTGE--------RPFECLK--CGRAFSQ---- 386
Query: 129 QRLGSSEGWENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGADGW 187
SS +Q HT+ P +C + S L H W
Sbjct: 387 ----SSNFLRHQKVHTQVRPYECSQCGKSFSRS-----------SALIQH---------W 422
Query: 188 GPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGKT 247
T P N LA+ TG ER ++CS+CG+
Sbjct: 423 RVHTGER---PYECSECGRAFNNNSNLAQHQKVHTG------------ERPFECSECGRD 467
Query: 248 YKHAGSLTNHRQSHTLGIYP--CAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRL 305
+ + L H++ HT G P C C K FSN L H ++H RPY C C + F
Sbjct: 468 FSQSSHLLRHQKVHT-GERPFECCDCGKAFSNSSTLIQHQKVHTGQRPYECSECRKSFSR 526
Query: 306 PRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSGELED 365
L++H + H GE+ P G A +S +E
Sbjct: 527 SSSLIQHWRIHTGEK-------------------------PYECSECGKAFAHSSTLIEH 561
Query: 366 SGLE-EYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFNAAALKNHVRA 422
+ + RP+ C +CG+ + LI H+K H TG Y CS C K ++L H R
Sbjct: 562 WRVHTKERPYECNECGKFFSQNSILIKHQKVH-TGEKPYKCSECGKFFSRKSSLICHWRV 620
Query: 423 H--HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSL 480
H RP + E G+ + L+ + H +E RPY+C +CG+A+ R +L
Sbjct: 621 HTGERPYE-CSECGRAFSSNSHLVRHQRVHTQE---------RPYECIQCGKAFSERSTL 670
Query: 481 VNHRHSH-RTGEYQCSLCPRKYPNLMALRNHVRVH 514
V H+ H R Y+CS C + + +L L H ++H
Sbjct: 671 VRHQKVHTRERTYECSQCGKLFSHLCNLAQHKKIH 705
Score = 141 bits (355), Expect = 7e-33
Identities = 142/572 (24%), Positives = 216/572 (37%), Gaps = 108/572 (18%)
Query: 1232 CQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHM---------E 1282
C C +++ L H+ ++ + + C CG+ F L L HQ+ H +
Sbjct: 116 CDMCGPFLKDILHLAEHQGTQSEEKPYTCGACGRDFWLNANLHQHQKEHSGGKPFRWYKD 175
Query: 1283 RRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQYSCPTCPKTYSNRMALK 1342
R + K + PF C + G+ + LL ++ ++GQ K YSN L
Sbjct: 176 RDALMKSSKVHLSENPFTCREGGKVILGSCDLLQ-LQAVDSGQ-------KPYSNLGQLP 227
Query: 1343 DHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHEETEREPANGQGGLDG 1402
+ + + C+ CG++F +L HLR H +E P G G
Sbjct: 228 EVC-------------TTQKLFECSNCGKAFLKSSTLPNHLRTH--SEEIPFTCPTG--G 270
Query: 1403 TAASEANLTGSQGLETQLGGAEPVPHLEDGVPRPGERSQSPIRAASSEAPEPLSWGAGKA 1462
E ++ G++ T +PH+ + S S +R E +
Sbjct: 271 NFLEEKSILGNKKFHTG-----EIPHVCKECGKAFSHS-SKLRKHQKFHTEVKYYECIAC 324
Query: 1463 GGWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSPCHAGD----CQLNGPTLSHMDSWDN 1518
G NH LT VH H+G+ C G S+
Sbjct: 325 GK------TFNHK-------LT-------FVHHQRIHSGERPYECDECGKAFSNRSHLIR 364
Query: 1519 RDNSSQLQPGSHS-SCSQCGKTYCQSGSLLNHNTNKTD-RHY-CLLCSKEFLNPVATKSH 1575
+ ++ G C +CG+ + QS + L H T R Y C C K F A H
Sbjct: 365 HE---KVHTGERPFECLKCGRAFSQSSNFLRHQKVHTQVRPYECSQCGKSFSRSSALIQH 421
Query: 1576 SHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVL 1635
H + + C +CG+AF ++ LA H + H
Sbjct: 422 WRVHTGERPYECSECGRAFNNNSNLAQHQKVHT--------------------------- 454
Query: 1636 PGQGKAQEAPSETPRGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNH 1695
G+ SE R +S R + T ERPF C CG+++ ++ +L+ H
Sbjct: 455 ---GERPFECSECGRDFSQSSHLLRHQKVHTG------ERPFECCDCGKAFSNSSTLIQH 505
Query: 1696 QKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVH 1754
QK HT Y CS C K SL H R HT K + CS CGKAF ++ L H RVH
Sbjct: 506 QKVHTGQRPYECSECRKSFSRSSSLIQHWRIHTGEKPYECSECGKAFAHSSTLIEHWRVH 565
Query: 1755 APREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
+E P+ C C + F + ++HQ+ H E
Sbjct: 566 T-KERPYECNECGKFFSQNSILIKHQKVHTGE 596
Score = 134 bits (338), Expect = 6e-31
Identities = 90/346 (26%), Positives = 147/346 (42%), Gaps = 40/346 (11%)
Query: 1045 LEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHP 1102
+ Q RP+ C+QCGK++ +L+ H ++H TG+ + C C R + N + H + H
Sbjct: 396 VHTQVRPYECSQCGKSFSRSSALIQHWRVH-TGERPYECSECGRAFNNNSNLAQHQKVHT 454
Query: 1103 RCKGSEPQVGPIPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLE 1162
+ E + S L+ + G +P + G + L + KV +
Sbjct: 455 GERPFECSECGRDFSQSSHLLRHQKVHTG--ERPFECCDCGKAFSNSSTLIQHQKVHTGQ 512
Query: 1163 EVARVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHR 1222
E + R+ T EK P+ C CG+++ H+ +LI H
Sbjct: 513 RPYECSECRKSFSRSSSLIQHWRIHTGEK----------PYECSECGKAFAHSSTLIEHW 562
Query: 1223 QSH-QTGHFGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHM 1281
+ H + + C C K FS L H+++H + ++CSECGK F + L H RVH
Sbjct: 563 RVHTKERPYECNECGKFFSQNSILIKHQKVHTGEKPYKCSECGKFFSRKSSLICHWRVH- 621
Query: 1282 ERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRSH-ETGQYSCPTCPKTYSNRMA 1340
+RP+ C +CGR + L+ H+R H + Y C C K +S R
Sbjct: 622 ------------TGERPYECSECGRAFSSNSHLVRHQRVHTQERPYECIQCGKAFSERST 669
Query: 1341 LKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREH 1386
L HQ++H+ R C+ CG+ F +L +H + H
Sbjct: 670 LVRHQKVHTRER----------TYECSQCGKLFSHLCNLAQHKKIH 705
Score = 125 bits (315), Expect = 3e-28
Identities = 80/259 (30%), Positives = 115/259 (44%), Gaps = 12/259 (4%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDRH--YCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
CS+CG+ + + +L H T C C ++F H H + F C DC
Sbjct: 433 CSECGRAFNNNSNLAQHQKVHTGERPFECSECGRDFSQSSHLLRHQKVHTGERPFECCDC 492
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPR 1650
GKAF + L H + H Q P + E R K+ + ++ + E P E
Sbjct: 493 GKAFSNSSTLIQHQKVHT---GQRPYECSECR--KSFSRSSSLIQHWRIHTGEKPYECSE 547
Query: 1651 GPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLC 1709
G++ A + KERP+ C +CG+ + L+ HQK HT Y CS C
Sbjct: 548 C-GKAF--AHSSTLIEHWRVHTKERPYECNECGKFFSQNSILIKHQKVHTGEKPYKCSEC 604
Query: 1710 PKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRH 1769
K SL H R HT + + CS CG+AF + + L H RVH +E P+ C C +
Sbjct: 605 GKFFSRKSSLICHWRVHTGERPYECSECGRAFSSNSHLVRHQRVHT-QERPYECIQCGKA 663
Query: 1770 FRRRISFVQHQQQHQEEWT 1788
F R + V+HQ+ H E T
Sbjct: 664 FSERSTLVRHQKVHTRERT 682
Score = 101 bits (251), Expect = 8e-21
Identities = 156/730 (21%), Positives = 251/730 (34%), Gaps = 189/730 (25%)
Query: 268 CAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEE 327
C +C +++ L H ++ +PY C C R F L L +HQ+ H G + +++
Sbjct: 116 CDMCGPFLKDILHLAEHQGTQSEEKPYTCGACGRDFWLNANLHQHQKEHSGGKPFRWYKD 175
Query: 328 KG--MPTTNGHTDESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRH 385
+ M ++ H E+ +++ GS +L + DSG + Y +
Sbjct: 176 RDALMKSSKVHLSENPFTCREGGKVILGSCDLLQL-QAVDSGQ------------KPYSN 222
Query: 386 AGSLINHRKSHQTGVYPCSLCSKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAPLLL 445
G L + + ++ CS C K ++ L NH+R
Sbjct: 223 LGQLPEVCTTQK--LFECSNCGKAFLKSSTLPNHLR------------------------ 256
Query: 446 AETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPN 503
TH EE P+ C G + L N + TGE + C C + + +
Sbjct: 257 ---THSEEI---------PFTCPTGGNFLEEKSILGNKKF--HTGEIPHVCKECGKAFSH 302
Query: 504 LMALRNHVRVHCKAARRSADIGAEGAPSHLKVELPPDPVEAEAAPHTDQDHVCKHEEEAT 563
LR H + H + + + A G + K+ H + H + E
Sbjct: 303 SSKLRKHQKFHTEV--KYYECIACGKTFNHKLTFV----------HHQRIHSGERPYE-- 348
Query: 564 DITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCG 623
C CG F + L RH H GE R F C CG
Sbjct: 349 -------------CDECGKAFSNRSHLIRHEKVH-TGE-------------RPFECLKCG 381
Query: 624 KSYRHSGSLINHRQTH-QTGDFSCGACAKHFHTMAAMKNHLRRHSRRRSRRHRKRAGGAS 682
+++ S + + H++ H Q + C C K F +A+ H R H+ R
Sbjct: 382 RAFSQSSNFLRHQKVHTQVRPYECSQCGKSFSRSSALIQHWRVHTGERPYE--------- 432
Query: 683 GGREAKLLAAESWTRELEDNEGLESPQDP-SGESPHGAEGNLESDGDCLQAESEGDKCGL 741
R +N L Q +GE P E +CG
Sbjct: 433 ---------CSECGRAFNNNSNLAQHQKVHTGERPF-----------------ECSECGR 466
Query: 742 ERDETHFQGDKESGGTGEG-LERKDASLLDNLDIPGEEGGGTHFCDSLTGVDEDQKPATG 800
+ ++ + TGE E D G F +S T + + QK TG
Sbjct: 467 DFSQSSHLLRHQKVHTGERPFECCDC--------------GKAFSNSSTLI-QHQKVHTG 511
Query: 801 QP--------NSSSHSANAVTGWQAGAA---HTCSDCGHSFPHATGLLSHRPCH-PPGIY 848
Q S S S++ + W+ + CS+CG +F H++ L+ H H Y
Sbjct: 512 QRPYECSECRKSFSRSSSLIQHWRIHTGEKPYECSECGKAFAHSSTLIEHWRVHTKERPY 571
Query: 849 QCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHRRQAHSSSG 908
+C+ C K F L H + H T +P+ C CG F ++ H R H+
Sbjct: 572 ECNECGKFFSQNSILIKHQKVH-----TGEKPYKCSECGKFFSRKSSLICHWR-VHTGER 625
Query: 909 MTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSAGYGHICGCCGQTYD 968
E S E A S L + ++ +R E C CG+ +
Sbjct: 626 PYECS----------ECGRAFSSNSHLVRHQRVHTQERPYE----------CIQCGKAFS 665
Query: 969 DLGSLERHHQ 978
+ +L RH +
Sbjct: 666 ERSTLVRHQK 675
Score = 38.5 bits (88), Expect = 0.061
Identities = 14/27 (51%), Positives = 19/27 (70%)
Query: 236 ERRYKCSQCGKTYKHAGSLTNHRQSHT 262
ER Y+CSQCGK + H +L H++ HT
Sbjct: 680 ERTYECSQCGKLFSHLCNLAQHKKIHT 706
Score = 33.5 bits (75), Expect = 2.0
Identities = 17/51 (33%), Positives = 24/51 (47%), Gaps = 1/51 (1%)
Query: 821 HTCSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNH 870
+ C CG +F + L+ H+ H Y+CS C K F L L H + H
Sbjct: 655 YECIQCGKAFSERSTLVRHQKVHTRERTYECSQCGKLFSHLCNLAQHKKIH 705
>gi|52138523 zinc finger protein 418 [Homo sapiens]
Length = 676
Score = 172 bits (436), Expect = 3e-42
Identities = 170/635 (26%), Positives = 249/635 (39%), Gaps = 117/635 (18%)
Query: 60 PGSLVNHRRTHETGLFPCTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHLQG 119
PG+ V+ ++ H C CG + + L H TH + + HR
Sbjct: 72 PGAGVSPKKAHS-----CEMCGAILGDILHLADHQGTHHKQ--KLHR------------- 111
Query: 120 ETVSTDSWGQRLGSSEGWENQTKHTEETPDCESVPDP----RAASGTWEDLPTRQREGLA 175
++WG +L S +Q ++ E P SV + R E+ + G
Sbjct: 112 ----CEAWGNKLYDSSNRPHQNQYLGEKPYRSSVEEALFVKRCKFHVSEESSIFIQSGKD 167
Query: 176 SHPGPE---DGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPP 232
P A G +NS P + + + S Q+ Q P
Sbjct: 168 FLPSSGLLLQEATHTGEKSNSKPECESPFQWGDTHYSCGECMKHSSTKHVFVQQ--QRLP 225
Query: 233 AEEERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQY 291
+ EE C +CGK++ S++NH++ HT Y C C K FS+ +L H R+H
Sbjct: 226 SREE--CYCWECGKSFSKYDSVSNHQRVHTGKRPYECGECGKSFSHKGSLVQHQRVHTGK 283
Query: 292 RPYHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQML 351
RPY C C + F L++HQ+ H GER P G +S
Sbjct: 284 RPYECGECGKSFSHKGSLVQHQRVHTGER----------PYECGECGKSFSQ-------- 325
Query: 352 NGSA---ELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQT-GVYPCSLCS 407
NG+ + +GE RP+ C +CG+ + G+LI H++ H + Y C C
Sbjct: 326 NGTLIKHQRVHTGE---------RPYECEECGKCFTQKGNLIQHQRGHTSERPYECEECG 376
Query: 408 KQLFNAAALKNHVRAHHRPR-QGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYK 466
K L H R H R R GE G+ L + H E RPY+
Sbjct: 377 KCFSQKGTLTEHHRVHTRERPYECGECGKSFSRKGHLRNHQRGHTGE---------RPYE 427
Query: 467 CSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVH-------CKA 517
C ECG+++ +G+L+ H+ SH TGE Y+C C + + L H RVH C
Sbjct: 428 CGECGKSFSRKGNLIQHQRSH-TGERPYECRECRKLFRGKSHLIEHQRVHTGERPYECNE 486
Query: 518 ARRSADIGAEGAPSHLKVELPPDPVE-AEAAPHTDQD-HVCKHEEEATDITPAADKTAAH 575
+S + G H +V P E +E Q + +H T P +
Sbjct: 487 CGKSFQ-DSSGFRVHQRVHTGEKPFECSECGKSFPQSCSLLRHRRVHTGERP-------Y 538
Query: 576 ICSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLINH 635
C CG F + SL RH TH A R + CR+CGK + SL+ H
Sbjct: 539 ECGECGKSFHQSSSLLRHQKTHTA--------------ERPYECRECGKFF---SSLLEH 581
Query: 636 RQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHSR 668
R+ H TG+ + C C K F +A H R H+R
Sbjct: 582 RRVH-TGERPYECRECGKTFTRRSAHFKHQRLHTR 615
Score = 152 bits (385), Expect = 2e-36
Identities = 121/467 (25%), Positives = 184/467 (39%), Gaps = 85/467 (18%)
Query: 960 CGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDIVNSVS--- 1016
CG CG+++ GSL +H + + K P G G + V V++
Sbjct: 260 CGECGKSFSHKGSLVQHQRVHTG-----KRPYECGECGKSFSHKGSLVQHQRVHTGERPY 314
Query: 1017 --GEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIH 1074
GE G + SQ G L + GE RP+ C +CGK + G+L+ H++ H
Sbjct: 315 ECGECGKSFSQNGT---LIKHQRVHTGE-------RPYECEECGKCFTQKGNLIQHQRGH 364
Query: 1075 QTG-DFLCPVCSRCYPNLAAYRNHLRNHPR--------CKGSEPQVGPIPEA----AGSS 1121
+ + C C +C+ H R H R C S + G + G
Sbjct: 365 TSERPYECEECGKCFSQKGTLTEHHRVHTRERPYECGECGKSFSRKGHLRNHQRGHTGER 424
Query: 1122 ELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKEEVWEETTVKGEE 1181
+ G + S K + + E + ++ R K + E V
Sbjct: 425 PYECGECGKSFSRKGNLIQHQRSHTGE-----RPYECRECRKLFRGKSHLIEHQRVH--- 476
Query: 1182 IEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGF 1239
+ ERP+ C CG+S++ + H++ H TG F C C K F
Sbjct: 477 ----------------TGERPYECNECGKSFQDSSGFRVHQRVH-TGEKPFECSECGKSF 519
Query: 1240 SNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGG------------ 1287
SL HRR+H R + C ECGK+F L HQ+ H R
Sbjct: 520 PQSCSLLRHRRVHTGERPYECGECGKSFHQSSSLLRHQKTHTAERPYECRECGKFFSSLL 579
Query: 1288 GTRKATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ-YSCPTCPKTYSNRMALKDHQR 1346
R+ +RP+ C +CG+T+ + H+R H G+ Y C C K+++ +L +H+R
Sbjct: 580 EHRRVHTGERPYECRECGKTFTRRSAHFKHQRLHTRGKPYECSECGKSFAETFSLTEHRR 639
Query: 1347 LHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHEETEREP 1393
+H+ R C+ CG+SF SL RH R H TER P
Sbjct: 640 VHTGER----------PYECSECGKSFHRSSSLLRHQRVH--TERSP 674
Score = 150 bits (379), Expect = 1e-35
Identities = 138/517 (26%), Positives = 204/517 (39%), Gaps = 90/517 (17%)
Query: 9 SCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRR 68
SC +C +H + + + L P+++ C +CG+ + S+ NH+R
Sbjct: 204 SCGECMKHSSTKHVFVQQQRL----PSREE---------CYCWECGKSFSKYDSVSNHQR 250
Query: 69 THETGLFP--CTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHLQGETVSTDS 126
H TG P C CGK FS+ +L H R H RP E GE + S
Sbjct: 251 VH-TGKRPYECGECGKSFSHKGSLVQHQRV--------HTGKRPYEC-----GECGKSFS 296
Query: 127 WGQRLGSSEGWENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGAD 185
L ++Q HT E P +C + +GT L QR P +
Sbjct: 297 HKGSLV-----QHQRVHTGERPYECGECGKSFSQNGT---LIKHQRVHTGERPYECEECG 348
Query: 186 GWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCG 245
+ NL Q+ ER Y+C +CG
Sbjct: 349 ----------------KCFTQKGNLIQHQRGHT----------------SERPYECEECG 376
Query: 246 KTYKHAGSLTNHRQSHTLGI-YPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFR 304
K + G+LT H + HT Y C C K FS L+NH R H RPY C C + F
Sbjct: 377 KCFSQKGTLTEHHRVHTRERPYECGECGKSFSRKGHLRNHQRGHTGERPYECGECGKSFS 436
Query: 305 LPRELLEHQQSHEGER----QEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTS 360
L++HQ+SH GER +E R +G H + ++ S + S+
Sbjct: 437 RKGNLIQHQRSHTGERPYECRECRKLFRGKSHLIEHQRVHTGERPYECNECGKSFQDSSG 496
Query: 361 GELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFNAAALKN 418
+ +PF C +CG+++ + SL+ HR+ H TG Y C C K +++L
Sbjct: 497 FRVHQRVHTGEKPFECSECGKSFPQSCSLLRHRRVH-TGERPYECGECGKSFHQSSSLLR 555
Query: 419 HVRAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRG 478
H + H R E + + LL H E RPY+C ECG+ + R
Sbjct: 556 HQKTHTAERP--YECRECGKFFSSLLEHRRVHTGE---------RPYECRECGKTFTRRS 604
Query: 479 SLVNHRHSHRTGE-YQCSLCPRKYPNLMALRNHVRVH 514
+ H+ H G+ Y+CS C + + +L H RVH
Sbjct: 605 AHFKHQRLHTRGKPYECSECGKSFAETFSLTEHRRVH 641
Score = 149 bits (376), Expect = 2e-35
Identities = 159/604 (26%), Positives = 229/604 (37%), Gaps = 135/604 (22%)
Query: 1158 VEPLEEVARVKEEVWEETTV-----------KGEEIEPRLETAEKGCQTEASSERPFSCE 1206
VE V R K V EE+++ G ++ T EK ++ E PF
Sbjct: 141 VEEALFVKRCKFHVSEESSIFIQSGKDFLPSSGLLLQEATHTGEKS-NSKPECESPFQWG 199
Query: 1207 ----VCGRSYKHAGS---LINHRQSHQTGHFGCQACSKGFSNLMSLKNHRRIHADPRRFR 1259
CG KH+ + + ++ C C K FS S+ NH+R+H R +
Sbjct: 200 DTHYSCGECMKHSSTKHVFVQQQRLPSREECYCWECGKSFSKYDSVSNHQRVHTGKRPYE 259
Query: 1260 CSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRR 1319
C ECGK+F + L HQRVH + RP+ CG+CG+++ H GSL+ H+R
Sbjct: 260 CGECGKSFSHKGSLVQHQRVHTGK-------------RPYECGECGKSFSHKGSLVQHQR 306
Query: 1320 SHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENR------------------RRRAGRS 1359
H TG+ Y C C K++S L HQR+H+ R + + G +
Sbjct: 307 VH-TGERPYECGECGKSFSQNGTLIKHQRVHTGERPYECEECGKCFTQKGNLIQHQRGHT 365
Query: 1360 RRTAVRCALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASEANLTGSQGLETQ 1419
C CG+ F +G+L H R H RE G + + + +L Q T
Sbjct: 366 SERPYECEECGKCFSQKGTLTEHHRVH---TRERPYECGECGKSFSRKGHLRNHQRGHT- 421
Query: 1420 LGGAEPVPHLEDG--VPRPGERSQSPIRAASSEAP----EPLSWGAGKA----------G 1463
G P E G R G Q R+ + E P E GK+ G
Sbjct: 422 --GERPYECGECGKSFSRKGNLIQHQ-RSHTGERPYECRECRKLFRGKSHLIEHQRVHTG 478
Query: 1464 GWP-----VGGGLGNHSGGWVPQFLTRSEEPEDSVHRSPCHAGDCQLNGPTLSHMDSWDN 1518
P G + SG V Q + E+P + C L L H
Sbjct: 479 ERPYECNECGKSFQDSSGFRVHQRVHTGEKPFECSECGKSFPQSCSL----LRH------ 528
Query: 1519 RDNSSQLQPGSHSSCSQCGKTYCQSGSLLNH-NTNKTDRHY-CLLCSKEFLNPVATKSHS 1576
R + +P C GK++ QS SLL H T+ +R Y C C K F + + H
Sbjct: 529 RRVHTGERPYECGEC---GKSFHQSSSLLRHQKTHTAERPYECRECGKFFSSLL---EHR 582
Query: 1577 HNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLP 1636
H + + C +CGK F H + H R
Sbjct: 583 RVHTGERPYECRECGKTFTRRSAHFKHQRLHTR--------------------------- 615
Query: 1637 GQGKAQEAPSETPRGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQ 1696
GK E SE + E+ + T ERP+ C++CG+S+ + SLL HQ
Sbjct: 616 --GKPYEC-SECGKSFAETFSLTEHRRVHTG------ERPYECSECGKSFHRSSSLLRHQ 666
Query: 1697 KAHT 1700
+ HT
Sbjct: 667 RVHT 670
Score = 145 bits (367), Expect = 3e-34
Identities = 98/342 (28%), Positives = 146/342 (42%), Gaps = 70/342 (20%)
Query: 1050 RPFRCNQCGKTYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGS 1107
RP+ C +CGK++ H GSLV H+++H TG + C C + + + + H R H
Sbjct: 256 RPYECGECGKSFSHKGSLVQHQRVH-TGKRPYECGECGKSFSHKGSLVQHQRVHT----- 309
Query: 1108 EPQVGPIPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARV 1167
+P E G ++ L + +V E
Sbjct: 310 -------------------------GERPYECGECGKSFSQNGTLIKHQRVHTGERPYEC 344
Query: 1168 KEEVWEETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQT 1227
EE + T KG I+ Q +SERP+ CE CG+ + G+L H + H
Sbjct: 345 -EECGKCFTQKGNLIQH---------QRGHTSERPYECEECGKCFSQKGTLTEHHRVHTR 394
Query: 1228 GH-FGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGG 1286
+ C C K FS L+NH+R H R + C ECGK+F + L HQR H
Sbjct: 395 ERPYECGECGKSFSRKGHLRNHQRGHTGERPYECGECGKSFSRKGNLIQHQRSH------ 448
Query: 1287 GGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDH 1344
+RP+ C +C + +R L+ H+R H TG+ Y C C K++ + + H
Sbjct: 449 -------TGERPYECRECRKLFRGKSHLIEHQRVH-TGERPYECNECGKSFQDSSGFRVH 500
Query: 1345 QRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREH 1386
QR+H+ + C+ CG+SFP SL RH R H
Sbjct: 501 QRVHTGEK----------PFECSECGKSFPQSCSLLRHRRVH 532
Score = 143 bits (360), Expect = 2e-33
Identities = 133/524 (25%), Positives = 201/524 (38%), Gaps = 78/524 (14%)
Query: 1258 FRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNH 1317
+ C EC K + QR+ +RE+ C +CG+++ S+ NH
Sbjct: 203 YSCGECMKHSSTKHVFVQQQRL------------PSREE--CYCWECGKSFSKYDSVSNH 248
Query: 1318 RRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPG 1375
+R H TG+ Y C C K++S++ +L HQR+H+ R C CG+SF
Sbjct: 249 QRVH-TGKRPYECGECGKSFSHKGSLVQHQRVHTGKR----------PYECGECGKSFSH 297
Query: 1376 RGSLERHLREHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDG--V 1433
+GSL +H R H ER G+ G + + L Q + T G P E G
Sbjct: 298 KGSLVQHQRVHTG-ERPYECGECGK--SFSQNGTLIKHQRVHT---GERPYECEECGKCF 351
Query: 1434 PRPGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSV 1493
+ G Q R +SE P G Q T +E
Sbjct: 352 TQKGNLIQHQ-RGHTSERPYECE-----------------ECGKCFSQKGTLTEHHRVHT 393
Query: 1494 HRSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHSSCSQCGKTYCQSGSLLNHNTNK 1553
P G+C + H+ + + C +CGK++ + G+L+ H +
Sbjct: 394 RERPYECGECGKSFSRKGHLRNHQRGHTGERPY-----ECGECGKSFSRKGNLIQHQRSH 448
Query: 1554 T-DRHY-CLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAH---- 1607
T +R Y C C K F H H + + C +CGK+F+ H + H
Sbjct: 449 TGERPYECRECRKLFRGKSHLIEHQRVHTGERPYECNECGKSFQDSSGFRVHQRVHTGEK 508
Query: 1608 ----ARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKA--------QEAPSETPRGPGES 1655
+ P R + TGE GK+ + + T P E
Sbjct: 509 PFECSECGKSFPQSCSLLRHRRVHTGERPYECGECGKSFHQSSSLLRHQKTHTAERPYEC 568
Query: 1656 VERARGGQAVTS-MAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLL 1713
E + ++ ERP+ C +CG+++ + HQ+ HT G Y CS C K
Sbjct: 569 RECGKFFSSLLEHRRVHTGERPYECRECGKTFTRRSAHFKHQRLHTRGKPYECSECGKSF 628
Query: 1714 PNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPR 1757
SL H R HT + + CS CGK+F ++ L H RVH R
Sbjct: 629 AETFSLTEHRRVHTGERPYECSECGKSFHRSSSLLRHQRVHTER 672
Score = 141 bits (355), Expect = 7e-33
Identities = 171/704 (24%), Positives = 264/704 (37%), Gaps = 112/704 (15%)
Query: 210 LEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSHTLGIYPCA 269
LE ++ S + G E ++P + + SQ G+ + +++H+ C
Sbjct: 35 LENWVLISSLGCWCGSEDEEAPSKKSISIQRVSQVSTP----GAGVSPKKAHS-----CE 85
Query: 270 ICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKG 329
+C +++ L +H H + + + C HQ + GE+ E+
Sbjct: 86 MCGAILGDILHLADHQGTHHKQKLHRCEAWGNKL-YDSSNRPHQNQYLGEKPYRSSVEEA 144
Query: 330 M--PTTNGHTDESS-------QDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCGD-- 378
+ H E S +D LPS+ +L E + +GE +S E PF+ GD
Sbjct: 145 LFVKRCKFHVSEESSIFIQSGKDFLPSSGLL--LQEATHTGEKSNSKPECESPFQWGDTH 202
Query: 379 --CGRTYRHAGS---LINHRKSHQTGVYPCSLCSKQLFNAAALKNHVRAH--HRPRQGVG 431
CG +H+ + + ++ C C K ++ NH R H RP + G
Sbjct: 203 YSCGECMKHSSTKHVFVQQQRLPSREECYCWECGKSFSKYDSVSNHQRVHTGKRPYE-CG 261
Query: 432 ENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE 491
E G+ L+ + H + RPY+C ECG+++ H+GSLV H+ H TGE
Sbjct: 262 ECGKSFSHKGSLVQHQRVHTGK---------RPYECGECGKSFSHKGSLVQHQRVH-TGE 311
Query: 492 --YQCSLCPRKYPNLMALRNHVRVHCKAARRSADIGAEGAPSHLKVELPPDPVEAEAAPH 549
Y+C C + + L H RVH P E E
Sbjct: 312 RPYECGECGKSFSQNGTLIKHQRVHTGER----------------------PYECEECGK 349
Query: 550 --TDQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKENSRT 607
T + ++ +H+ T P + C CG F +L H H
Sbjct: 350 CFTQKGNLIQHQRGHTSERP-------YECEECGKCFSQKGTLTEHHRVH---------- 392
Query: 608 ETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRR 665
+ R + C +CGKS+ G L NH++ H TG+ + CG C K F + H R
Sbjct: 393 ----TRERPYECGECGKSFSRKGHLRNHQRGH-TGERPYECGECGKSFSRKGNLIQHQRS 447
Query: 666 HSRRRS---RRHRKRAGGASGGREAKLLAAESWTRELEDNEGLESPQDPSGESPHGAEGN 722
H+ R R RK G S E + + + R E NE +S QD SG H
Sbjct: 448 HTGERPYECRECRKLFRGKSHLIEHQRV--HTGERPYECNECGKSFQDSSGFRVHQRVHT 505
Query: 723 LESDGDCLQA-ESEGDKCGLERDETHFQGDK--ESGGTGEGLERKDASLLDNLDIPGEEG 779
E +C + +S C L R G++ E G G+ + + L E
Sbjct: 506 GEKPFECSECGKSFPQSCSLLRHRRVHTGERPYECGECGKSFHQSSSLLRHQKTHTAERP 565
Query: 780 GGTHFCDSL-TGVDEDQKPATGQ-PNSSSHSANAVTGWQA----------GAAHTCSDCG 827
C + + E ++ TG+ P T A G + CS+CG
Sbjct: 566 YECRECGKFFSSLLEHRRVHTGERPYECRECGKTFTRRSAHFKHQRLHTRGKPYECSECG 625
Query: 828 HSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNH 870
SF L HR H Y+CS C K F +L H + H
Sbjct: 626 KSFAETFSLTEHRRVHTGERPYECSECGKSFHRSSSLLRHQRVH 669
Score = 137 bits (344), Expect = 1e-31
Identities = 158/649 (24%), Positives = 240/649 (36%), Gaps = 115/649 (17%)
Query: 1198 SSERPFSCEVCGRSYKHAGSLINHRQSHQTGHFG-CQACSKGFSNLMSLKNHRRIHADPR 1256
S ++ SCE+CG L +H+ +H C+A + S + H+ + +
Sbjct: 77 SPKKAHSCEMCGAILGDILHLADHQGTHHKQKLHRCEAWGNKLYD-SSNRPHQNQYLGEK 135
Query: 1257 RFRCS----------------------ECGKAFRLRKQLASHQRVHMERRGGGGTRKATR 1294
+R S + GK F L + H G +
Sbjct: 136 PYRSSVEEALFVKRCKFHVSEESSIFIQSGKDFLPSSGLLLQEATHT----GEKSNSKPE 191
Query: 1295 EDRPFRCGQ----CGRTYRHAGS---LLNHRRSHETGQYSCPTCPKTYSNRMALKDHQRL 1347
+ PF+ G CG +H+ + + +R + C C K++S ++ +HQR+
Sbjct: 192 CESPFQWGDTHYSCGECMKHSSTKHVFVQQQRLPSREECYCWECGKSFSKYDSVSNHQRV 251
Query: 1348 HSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASE 1407
H+ R C CG+SF +GSL +H R H T + P G + + +
Sbjct: 252 HTGKR----------PYECGECGKSFSHKGSLVQHQRVH--TGKRPYEC-GECGKSFSHK 298
Query: 1408 ANLTGSQGLETQLGGAEPVPHLEDGVPRPGERSQSPI---RAASSEAPEPLSWGAGKAGG 1464
+L Q + T G P E G + ++ + I R + E P GK
Sbjct: 299 GSLVQHQRVHT---GERPYECGECG--KSFSQNGTLIKHQRVHTGERPYECE-ECGKC-- 350
Query: 1465 WPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSPCHAGDCQLNGPTLSHMDSWDNRDNSSQ 1524
+ G L H G + EE G C TL+ R+ +
Sbjct: 351 FTQKGNLIQHQRGHTSERPYECEE-----------CGKCFSQKGTLTEHHRVHTRERPYE 399
Query: 1525 LQPGSHSSCSQCGKTYCQSGSLLNHNTNKT-DRHY-CLLCSKEFLNPVATKSHSHNHIDA 1582
C +CGK++ + G L NH T +R Y C C K F H +H
Sbjct: 400 --------CGECGKSFSRKGHLRNHQRGHTGERPYECGECGKSFSRKGNLIQHQRSHTGE 451
Query: 1583 QTFACPDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQ 1642
+ + C +C K F L H + H + ++ +G Q V G+ K
Sbjct: 452 RPYECRECRKLFRGKSHLIEHQRVHTGERPYECNECGKSFQDSSGFRVHQRVHTGE-KPF 510
Query: 1643 EAPSETPRGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTG 1702
E SE + +S R + T ERP+ C +CG+S+ + SLL HQK HT
Sbjct: 511 EC-SECGKSFPQSCSLLRHRRVHTG------ERPYECGECGKSFHQSSSLLRHQKTHTAE 563
Query: 1703 L-YPCSLCPKLLPNLLSLKN-------------------------HSRTHTDPKRHCCSI 1736
Y C C K +LL + H R HT K + CS
Sbjct: 564 RPYECRECGKFFSSLLEHRRVHTGERPYECRECGKTFTRRSAHFKHQRLHTRGKPYECSE 623
Query: 1737 CGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQE 1785
CGK+F L H RVH E P+ C C + F R S ++HQ+ H E
Sbjct: 624 CGKSFAETFSLTEHRRVHTG-ERPYECSECGKSFHRSSSLLRHQRVHTE 671
Score = 132 bits (333), Expect = 2e-30
Identities = 166/700 (23%), Positives = 249/700 (35%), Gaps = 130/700 (18%)
Query: 611 MSPPRAFACRDCGKSYRHSGSLINHRQTHQTGDFSCGACAKHFHTMAAMKNHLRRHSRR- 669
+SP +A +C CG L +H+ TH + H A N L S R
Sbjct: 76 VSPKKAHSCEMCGAILGDILHLADHQGTHHK---------QKLHRCEAWGNKLYDSSNRP 126
Query: 670 RSRRHRKRAGGASGGREAKLLAAESWTRELEDNEGLESPQDPSGESPHGAEGNLESDGDC 729
++ S EA + + E + ++S +D L S G
Sbjct: 127 HQNQYLGEKPYRSSVEEALFVKRCKFHVSEESSIFIQSGKD-----------FLPSSGLL 175
Query: 730 LQ-AESEGDKCGLERD-ETHFQGDKESGGTGEGLERKDAS--LLDNLDIPGEEGGGTHFC 785
LQ A G+K + + E+ FQ GE ++ + +P E C
Sbjct: 176 LQEATHTGEKSNSKPECESPFQWGDTHYSCGECMKHSSTKHVFVQQQRLPSREECYCWEC 235
Query: 786 ----DSLTGVDEDQKPATGQP--------NSSSHSANAVTGWQAGAAHT------CSDCG 827
V Q+ TG+ S SH + V Q HT C +CG
Sbjct: 236 GKSFSKYDSVSNHQRVHTGKRPYECGECGKSFSHKGSLV---QHQRVHTGKRPYECGECG 292
Query: 828 HSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLC 886
SF H L+ H+ H Y+C C K F L H + H T +P+ C C
Sbjct: 293 KSFSHKGSLVQHQRVHTGERPYECGECGKSFSQNGTLIKHQRVH-----TGERPYECEEC 347
Query: 887 GMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQR 946
G F + H+R G T E EE G + L+E ++ +R
Sbjct: 348 GKCFTQKGNLIQHQR------GHTSERPYECEECGKCFSQKGT-----LTEHHRVHTRER 396
Query: 947 EVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDS 1006
E CG CG+++ G L H + G T ++ P G G + +
Sbjct: 397 PYE----------CGECGKSFSRKGHLRNHQR----GHTGER-PYECGECGKSFSRKGNL 441
Query: 1007 VLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYRHGGS 1066
+ S +GE + +E G S I+ + RP+ CN+CGK+++
Sbjct: 442 IQHQ--RSHTGER-PYECRECRKLFRGKSHLIE--HQRVHTGERPYECNECGKSFQDSSG 496
Query: 1067 LVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAAGSSELQ 1124
H+++H TG+ F C C + +P + H R H
Sbjct: 497 FRVHQRVH-TGEKPFECSECGKSFPQSCSLLRHRRVHT---------------------- 533
Query: 1125 VGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKEEVWEETTVKGEEIEP 1184
+P E G + L K E +E G+
Sbjct: 534 --------GERPYECGECGKSFHQSSSLLRHQKTHTAERPYECRE--------CGKFFSS 577
Query: 1185 RLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH-FGCQACSKGFSNLM 1243
LE + + ERP+ C CG+++ + H++ H G + C C K F+
Sbjct: 578 LLEH-----RRVHTGERPYECRECGKTFTRRSAHFKHQRLHTRGKPYECSECGKSFAETF 632
Query: 1244 SLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMER 1283
SL HRR+H R + CSECGK+F L HQRVH ER
Sbjct: 633 SLTEHRRVHTGERPYECSECGKSFHRSSSLLRHQRVHTER 672
Score = 127 bits (318), Expect = 1e-28
Identities = 86/296 (29%), Positives = 128/296 (43%), Gaps = 19/296 (6%)
Query: 1495 RSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHS-SCSQCGKTYCQSGSLLNHNTNK 1553
R C+ +C G + S DS N ++ G C +CGK++ GSL+ H
Sbjct: 227 REECYCWEC---GKSFSKYDSVSNHQ---RVHTGKRPYECGECGKSFSHKGSLVQHQRVH 280
Query: 1554 TDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGH 1611
T + + C C K F + + H H + + C +CGK+F + L H + H
Sbjct: 281 TGKRPYECGECGKSFSHKGSLVQHQRVHTGERPYECGECGKSFSQNGTLIKHQRVHT--- 337
Query: 1612 SQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVERARGGQAVTSMAAE 1671
+ P + EE K T + ++ +G E P E G+ + G
Sbjct: 338 GERPYECEECG--KCFTQKGNLIQHQRGHTSERPYECEEC-GKCFSQK--GTLTEHHRVH 392
Query: 1672 DKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLCPKLLPNLLSLKNHSRTHTDPK 1730
+ERP+ C +CG+S+ G L NHQ+ HT Y C C K +L H R+HT +
Sbjct: 393 TRERPYECGECGKSFSRKGHLRNHQRGHTGERPYECGECGKSFSRKGNLIQHQRSHTGER 452
Query: 1731 RHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
+ C C K FR + L H RVH E P+ C C + F+ F HQ+ H E
Sbjct: 453 PYECRECRKLFRGKSHLIEHQRVHT-GERPYECNECGKSFQDSSGFRVHQRVHTGE 507
Score = 124 bits (311), Expect = 8e-28
Identities = 85/296 (28%), Positives = 125/296 (42%), Gaps = 19/296 (6%)
Query: 1495 RSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHS-SCSQCGKTYCQSGSLLNHNTNK 1553
+ P G+C G + SH S ++ G C +CGK++ Q+G+L+ H
Sbjct: 283 KRPYECGEC---GKSFSHKGSLVQHQ---RVHTGERPYECGECGKSFSQNGTLIKHQRVH 336
Query: 1554 T-DRHY-CLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGH 1611
T +R Y C C K F H H + + C +CGK F L H + H R
Sbjct: 337 TGERPYECEECGKCFTQKGNLIQHQRGHTSERPYECEECGKCFSQKGTLTEHHRVHTRER 396
Query: 1612 SQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVERARGGQAVTSMAAE 1671
+ ++ K Q +G E P E G+S R G + +
Sbjct: 397 PYECGECGKSFSRKGHLRNHQ-----RGHTGERPYECGEC-GKSFSRK--GNLIQHQRSH 448
Query: 1672 DKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPK 1730
ERP+ C +C + +R L+ HQ+ HT Y C+ C K + + H R HT K
Sbjct: 449 TGERPYECRECRKLFRGKSHLIEHQRVHTGERPYECNECGKSFQDSSGFRVHQRVHTGEK 508
Query: 1731 RHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
CS CGK+F + L H RVH E P+ C C + F + S ++HQ+ H E
Sbjct: 509 PFECSECGKSFPQSCSLLRHRRVHTG-ERPYECGECGKSFHQSSSLLRHQKTHTAE 563
Score = 52.8 bits (125), Expect = 3e-06
Identities = 24/57 (42%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Query: 239 YKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPY 294
Y+CS+CGK++ SLT HR+ HT Y C+ C K F +L H R+H + PY
Sbjct: 619 YECSECGKSFAETFSLTEHRRVHTGERPYECSECGKSFHRSSSLLRHQRVHTERSPY 675
Score = 52.0 bits (123), Expect = 5e-06
Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 16/92 (17%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C + F SL E HR + + RPY C++CG+ + + H+R
Sbjct: 568 CRECGKFFSSLLE---HRRV------------HTGERPYECRECGKTFTRRSAHFKHQRL 612
Query: 70 HETGL-FPCTTCGKDFSNPMALKSHMRTHAPE 100
H G + C+ CGK F+ +L H R H E
Sbjct: 613 HTRGKPYECSECGKSFAETFSLTEHRRVHTGE 644
Score = 40.8 bits (94), Expect = 0.012
Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 12/61 (19%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
CS+C + F L+ HR + + RPY C +CG+ + SL+ H+R
Sbjct: 621 CSECGKSFAETFSLTEHRRV------------HTGERPYECSECGKSFHRSSSLLRHQRV 668
Query: 70 H 70
H
Sbjct: 669 H 669
Score = 32.7 bits (73), Expect = 3.3
Identities = 21/72 (29%), Positives = 35/72 (48%), Gaps = 8/72 (11%)
Query: 1670 AEDKERPFRCT---QCGRSYRHAGSLLNHQKAHTTGLYPCSLCPKLLPNLLSLKNHSRTH 1726
+ED+E P + + Q G+ ++ +KAH+ C +C +L ++L L +H TH
Sbjct: 50 SEDEEAPSKKSISIQRVSQVSTPGAGVSPKKAHS-----CEMCGAILGDILHLADHQGTH 104
Query: 1727 TDPKRHCCSICG 1738
K H C G
Sbjct: 105 HKQKLHRCEAWG 116
>gi|122937213 zinc finger protein 99 [Homo sapiens]
Length = 1036
Score = 172 bits (435), Expect = 4e-42
Identities = 210/974 (21%), Positives = 352/974 (36%), Gaps = 224/974 (22%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C + F L+RH+ + + +PY+C++CG+ + H +L H+
Sbjct: 196 CEECGKAFKQSSHLTRHKAI------------HTGEKPYKCEECGKAFNHFSALRKHQII 243
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPEGRRRHR---------PPRPKEATPHLQ 118
H TG P C CGK FS L+ H H E ++ K H
Sbjct: 244 H-TGKKPYKCEECGKAFSQSSTLRKHEIIHTEEKPYKYEECGKAFSNLSALRKHEIIHTG 302
Query: 119 GETVSTDSWGQRL-GSSEGWENQTKHTEETPDCESVPDPRAASGTWEDLPTRQREGLASH 177
+ + G+ SS+ ++ HT E P C+ +A ++ L H
Sbjct: 303 QKPYKCEECGKAFKWSSKLTVHKVIHTAEKP-CKCEECGKA---------FKRFSALRKH 352
Query: 178 PGPEDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEER 237
++ + P S SN +++ G++P
Sbjct: 353 -----------KIIHTGKQPYKCEECSKAFSNFSALRKHEIIH--TGEKP---------- 389
Query: 238 RYKCSQCGKTYKHAGSLTNHRQSHTLGIYPCAI--CFKEFSNLMALKNHSRLHAQYRPYH 295
YKC +CGK +K + LT H+ H + PC C K F + AL+ H +H +PY
Sbjct: 390 -YKCEECGKAFKWSSKLTVHKVIH-MEEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYK 447
Query: 296 CPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSA 355
C C + F L++H+ H G++ + EE G + S+
Sbjct: 448 CEECGKAFNNSSTLMKHKIIHTGKKPY-KCEECG-------------------KAFKQSS 487
Query: 356 ELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFNA 413
L+ + +P++C +CG+ + H +L H+ H TG Y C C K +
Sbjct: 488 HLTRHKAIHTG----EKPYKCEECGKAFNHFSALRKHQIIH-TGKKPYKCEECGKAFSQS 542
Query: 414 AALKNHVRAH--HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECG 471
+ L+ H H +P + E G+ + L + H EE +PYKC ECG
Sbjct: 543 STLRKHEIIHTGEKPYK-CEECGKAFKWSSHLTRHKVIHTEE---------KPYKCEECG 592
Query: 472 RAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVH-------CKAARRSA 522
+A+ H +L H+ H TG+ Y+C C + + LR H +H C+ ++
Sbjct: 593 KAFNHFSALRKHKIIH-TGKKPYKCEECGKAFSQSSTLRKHEIIHTGEKPYKCEECGKAF 651
Query: 523 DIGAEGAPSHLKVELPPDPVEAEAAPHTDQ--DHVCKHEEEATDITPAADKTAAHICSIC 580
++ H + P + E + + KH+ T P + C C
Sbjct: 652 KWSSK-LTVHKVIHTAEKPCKCEECGKAFKHFSALRKHKIIHTGKKP-------YKCEEC 703
Query: 581 GLLFEDAESLERHGLTHGAGEK-------------------------------ENSRT-- 607
G F ++ +L +H + H GEK NS T
Sbjct: 704 GKAFNNSSTLRKHEIIH-TGEKSYKCEECALRKHEIIHTGKKPYKCEECGKAFNNSSTLR 762
Query: 608 --ETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHL 663
+ + + + C +CGK+++ S L H+ H TG+ + CG C K F+ + +K H
Sbjct: 763 KHKIIYTGKKPYKCEECGKAFKQSSHLTRHKAVH-TGEKPYKCGECGKAFNNSSTLKKHK 821
Query: 664 RRHSRRRSRRHR---KRAGGASGGREAKLLAAESWTRELEDNEGLESPQDPSGESPHGAE 720
H+R +S + K S R+ K++ +GE P+ E
Sbjct: 822 LIHTREKSYKCEECGKAFSNFSALRKHKII--------------------HTGEKPYKCE 861
Query: 721 GNLESDGDCLQAESEGDKCGLERDETHFQGDK--ESGGTGEGLERKDASLLDNLDIPGEE 778
+C ++ + L + + G+K + G+G + + GE+
Sbjct: 862 -------ECECGKAFNNSSTLMKHKIIHTGEKPYKCEECGKGFNNFSTLMKHKIIHTGEK 914
Query: 779 GGGTHFCDSLTGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHTCSDCGHSFPHATGLLS 838
C SSH + + C + G +F H + L
Sbjct: 915 PYKCEECGKAF-------------KQSSHLTKHKSIHTGEKPYKCEERGKAFSHFSRLTK 961
Query: 839 HR------------PCHPPGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLC 886
HR C P Y+C C K F+ L H H T + + C C
Sbjct: 962 HRIIHTGKKPYKCEECEKP--YKCEECGKAFNQSSHLTQHKTIH-----TGGKTYKCEEC 1014
Query: 887 GMIFPGRAGYRLHR 900
G F + H+
Sbjct: 1015 GKAFNHLSALTKHK 1028
Score = 171 bits (434), Expect = 5e-42
Identities = 193/859 (22%), Positives = 322/859 (37%), Gaps = 160/859 (18%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C + F +L+ H+ ++H + +P +C++CG+ ++ +L H+
Sbjct: 308 CEECGKAFKWSSKLTVHK-VIHTAE-----------KPCKCEECGKAFKRFSALRKHKII 355
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHLQGETVSTDSW 127
H TG P C C K FSN AL+ H H E P+ E W
Sbjct: 356 H-TGKQPYKCEECSKAFSNFSALRKHEIIHTGE-------------KPYKCEECGKAFKW 401
Query: 128 GQRLGSSEGWENQTKHTEETPDCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGADGW 187
+L ++ H EE P C+ +A + L H
Sbjct: 402 SSKLTV-----HKVIHMEEKP-CKCEECGKAF---------KHFSALRKHK--------- 437
Query: 188 GPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGKT 247
++ + P +N + +++ G++P YKC +CGK
Sbjct: 438 --IIHTGKKPYKCEECGKAFNNSSTLMKHKIIHT--GKKP-----------YKCEECGKA 482
Query: 248 YKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLP 306
+K + LT H+ HT Y C C K F++ AL+ H +H +PY C C + F
Sbjct: 483 FKQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSALRKHQIIHTGKKPYKCEECGKAFSQS 542
Query: 307 RELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSGELEDS 366
L +H+ H GE+ + EE G + S+ L+ +
Sbjct: 543 STLRKHEIIHTGEKPY-KCEECG-------------------KAFKWSSHLTRHKVIHT- 581
Query: 367 GLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTGV--YPCSLCSKQLFNAAALKNHVRAH- 423
E +P++C +CG+ + H +L H+ H TG Y C C K ++ L+ H H
Sbjct: 582 ---EEKPYKCEECGKAFNHFSALRKHKIIH-TGKKPYKCEECGKAFSQSSTLRKHEIIHT 637
Query: 424 -HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVN 482
+P + E G+ + L + + H E +P KC ECG+A++H +L
Sbjct: 638 GEKPYK-CEECGKAFKWSSKLTVHKVIHTAE---------KPCKCEECGKAFKHFSALRK 687
Query: 483 HRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHCKAARRSADIGAEGAPSHLKVELPPD 540
H+ H TG+ Y+C C + + N LR H +H + A + P
Sbjct: 688 HKIIH-TGKKPYKCEECGKAFNNSSTLRKHEIIHTGEKSYKCEECALRKHEIIHTGKKPY 746
Query: 541 PVEAEAAPHTDQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAG 600
E + + KH+ T P + C CG F+ + L RH H G
Sbjct: 747 KCEECGKAFNNSSTLRKHKIIYTGKKP-------YKCEECGKAFKQSSHLTRHKAVH-TG 798
Query: 601 EKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTH-QTGDFSCGACAKHFHTMAAM 659
EK + C +CGK++ +S +L H+ H + + C C K F +A+
Sbjct: 799 EKP-------------YKCGECGKAFNNSSTLKKHKLIHTREKSYKCEECGKAFSNFSAL 845
Query: 660 KNHLRRHSRRRSRRHRKRAGGASGGREAKLL------AAESWTRELEDNEGLESPQD--- 710
+ H H+ + + + G + + L+ E + E +G +
Sbjct: 846 RKHKIIHTGEKPYKCEECECGKAFNNSSTLMKHKIIHTGEKPYKCEECGKGFNNFSTLMK 905
Query: 711 ----PSGESPHGAEGNLESDGDCLQAESEGDKCGLERDETHFQGDKESGGTGEGLERKDA 766
+GE P+ E +C +A + L + ++ G+K G
Sbjct: 906 HKIIHTGEKPYKCE-------ECGKAFKQSSH--LTKHKSIHTGEKPYKCEERGKAFSHF 956
Query: 767 SLLDNLDI--PGEEGGGTHFCDSLTGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHTCS 824
S L I G++ C+ +E K N SSH T G + C
Sbjct: 957 SRLTKHRIIHTGKKPYKCEECEKPYKCEECGKAF----NQSSHLTQHKTIHTGGKTYKCE 1012
Query: 825 DCGHSFPHATGLLSHRPCH 843
+CG +F H + L H+ H
Sbjct: 1013 ECGKAFNHLSALTKHKIIH 1031
Score = 168 bits (426), Expect = 4e-41
Identities = 161/670 (24%), Positives = 247/670 (36%), Gaps = 125/670 (18%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C + F L+RH+ + + +PY+C++CG+ + H +L H+
Sbjct: 476 CEECGKAFKQSSHLTRHKAI------------HTGEKPYKCEECGKAFNHFSALRKHQII 523
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHLQGETVSTDSW 127
H TG P C CGK FS L+ H H E P+ E W
Sbjct: 524 H-TGKKPYKCEECGKAFSQSSTLRKHEIIHTGE-------------KPYKCEECGKAFKW 569
Query: 128 GQRLGSSEGWENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGADG 186
L ++ HTEE P CE G + + R+ H G +
Sbjct: 570 SSHLT-----RHKVIHTEEKPYKCEEC-------GKAFNHFSALRKHKIIHTGKK----- 612
Query: 187 WGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGK 246
P + L + + TG E+ YKC +CGK
Sbjct: 613 -----------PYKCEECGKAFSQSSTLRKHEIIHTG------------EKPYKCEECGK 649
Query: 247 TYKHAGSLTNHRQSHTLGI-YPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRL 305
+K + LT H+ HT C C K F + AL+ H +H +PY C C + F
Sbjct: 650 AFKWSSKLTVHKVIHTAEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNN 709
Query: 306 PRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSGELED 365
L +H+ H GE+ E HT + + N S+ L +
Sbjct: 710 SSTLRKHEIIHTGEKSYKCEECALRKHEIIHTGKKPYKCEECGKAFNNSSTLRKHKIIYT 769
Query: 366 SGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTGV--YPCSLCSKQLFNAAALKNHVRAH 423
+P++C +CG+ ++ + L H+ H TG Y C C K N++ LK H H
Sbjct: 770 GK----KPYKCEECGKAFKQSSHLTRHKAVH-TGEKPYKCGECGKAFNNSSTLKKHKLIH 824
Query: 424 HRPRQGVGEN-GQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSEC--GRAYRHRGSL 480
R + E G+ + L + H E +PYKC EC G+A+ + +L
Sbjct: 825 TREKSYKCEECGKAFSNFSALRKHKIIHTGE---------KPYKCEECECGKAFNNSSTL 875
Query: 481 VNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHCKAARRSADIGAEGAPSHLKVELP 538
+ H+ H TGE Y+C C + + N L H +H
Sbjct: 876 MKHKIIH-TGEKPYKCEECGKGFNNFSTLMKHKIIHTGEK-------------------- 914
Query: 539 PDPVEAEAAPHTDQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHG 598
P E H+ KH+ T P + C G F L +H + H
Sbjct: 915 PYKCEECGKAFKQSSHLTKHKSIHTGEKP-------YKCEERGKAFSHFSRLTKHRIIHT 967
Query: 599 AGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTG-DFSCGACAKHFHTMA 657
K+ + E P + C +CGK++ S L H+ H G + C C K F+ ++
Sbjct: 968 G--KKPYKCEECEKP---YKCEECGKAFNQSSHLTQHKTIHTGGKTYKCEECGKAFNHLS 1022
Query: 658 AMKNHLRRHS 667
A+ H H+
Sbjct: 1023 ALTKHKIIHT 1032
Score = 167 bits (424), Expect = 7e-41
Identities = 204/968 (21%), Positives = 346/968 (35%), Gaps = 184/968 (19%)
Query: 821 HTCSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQ 879
+ C +CG +F ++ L H+ H Y+C C K F+ ALR H H T +
Sbjct: 194 YKCEECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSALRKHQIIH-----TGKK 248
Query: 880 PFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVA----------EAAPAR 929
P+ C CG F + R H H TE + EE G A E
Sbjct: 249 PYKCEECGKAFSQSSTLRKH-EIIH-----TEEKPYKYEECGKAFSNLSALRKHEIIHTG 302
Query: 930 SPPLQLSEAELLNQLQREV---EALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTA 986
P + E + ++ + + +A C CG+ + +L +H +
Sbjct: 303 QKPYKCEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGKAFKRFSALRKHKIIHTG---- 358
Query: 987 DKAPSPLGVAGDAMEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLE 1046
K P A +I++ +GE + G L + ++
Sbjct: 359 -KQPYKCEECSKAFSNFSALRKHEIIH--TGEKPYKCEECGKAFKWSSKLTV---HKVIH 412
Query: 1047 AQPRPFRCNQCGKTYRHGGSLVNHRKIHQTG--DFLCPVCSRCYPNLAAYRNHLRNHPRC 1104
+ +P +C +CGK ++H +L H+ IH TG + C C + + N + H H
Sbjct: 413 MEEKPCKCEECGKAFKHFSALRKHKIIH-TGKKPYKCEECGKAFNNSSTLMKHKIIH--- 468
Query: 1105 KGSEPQVGPIPEAAGSSELQVGPIPEGGS----NKPQHMAEEGPGQAEVEKLQEELKVEP 1160
G +P E G + Q + + KP E G L++ +
Sbjct: 469 TGKKPYK---CEECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSALRKHQIIHT 525
Query: 1161 LEEVARVKE---EVWEETTVKGEEIEPRLETAEKGCQTEA------------------SS 1199
++ + +E + +T++ EI + T EK + E +
Sbjct: 526 GKKPYKCEECGKAFSQSSTLRKHEI---IHTGEKPYKCEECGKAFKWSSHLTRHKVIHTE 582
Query: 1200 ERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPRR 1257
E+P+ CE CG+++ H +L H+ H TG + C+ C K FS +L+ H IH +
Sbjct: 583 EKPYKCEECGKAFNHFSALRKHKIIH-TGKKPYKCEECGKAFSQSSTLRKHEIIHTGEKP 641
Query: 1258 FRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNH 1317
++C ECGKAF+ +L H+ +H ++P +C +CG+ ++H +L H
Sbjct: 642 YKCEECGKAFKWSSKLTVHKVIH-------------TAEKPCKCEECGKAFKHFSALRKH 688
Query: 1318 RRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSEN----------RRRRAGRSRRTAVR 1365
+ H TG+ Y C C K ++N L+ H+ +H+ R+ + + +
Sbjct: 689 KIIH-TGKKPYKCEECGKAFNNSSTLRKHEIIHTGEKSYKCEECALRKHEIIHTGKKPYK 747
Query: 1366 CALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEP 1425
C CG++F +L +H + T ++P + ++LT + + T G +P
Sbjct: 748 CEECGKAFNNSSTLRKHKIIY--TGKKPYKCE-ECGKAFKQSSHLTRHKAVHT---GEKP 801
Query: 1426 VPHLEDGVPRPGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTR 1485
E G + + + GKA N S + +
Sbjct: 802 YKCGECGKAFNNSSTLKKHKLIHTREKSYKCEECGKA--------FSNFSALRKHKIIHT 853
Query: 1486 SEEPEDSVHRSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHSSCSQCGKTYCQSGS 1545
E+P C G N TL ++ + +P C GK + +
Sbjct: 854 GEKPYKC---EECECGKAFNNSSTL-----MKHKIIHTGEKPYKCEEC---GKGFNNFST 902
Query: 1546 LLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASH 1603
L+ H T + C C K F H H + + C + GKAF L H
Sbjct: 903 LMKHKIIHTGEKPYKCEECGKAFKQSSHLTKHKSIHTGEKPYKCEERGKAFSHFSRLTKH 962
Query: 1604 LQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVERARGGQ 1663
H + P + EE P
Sbjct: 963 RIIHT---GKKPYKCEECEKP--------------------------------------- 980
Query: 1664 AVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTG-LYPCSLCPKLLPNLLSLKNH 1722
++C +CG+++ + L H+ HT G Y C C K +L +L H
Sbjct: 981 -------------YKCEECGKAFNQSSHLTQHKTIHTGGKTYKCEECGKAFNHLSALTKH 1027
Query: 1723 SRTHTDPK 1730
HT K
Sbjct: 1028 KIIHTGEK 1035
Score = 152 bits (383), Expect = 4e-36
Identities = 122/462 (26%), Positives = 202/462 (43%), Gaps = 67/462 (14%)
Query: 236 ERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPY 294
++ YKC +CGK +K + LT H+ HT Y C C K F++ AL+ H +H +PY
Sbjct: 191 KKPYKCEECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSALRKHQIIHTGKKPY 250
Query: 295 HCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTN---------GHTDESSQDQL 345
C C + F L +H+ H E + ++EE G +N HT +
Sbjct: 251 KCEECGKAFSQSSTLRKHEIIHT-EEKPYKYEECGKAFSNLSALRKHEIIHTGQKPYKCE 309
Query: 346 PSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPC 403
+ S++L+ + + +P +C +CG+ ++ +L H+ H TG Y C
Sbjct: 310 ECGKAFKWSSKLTVHKVIHTA----EKPCKCEECGKAFKRFSALRKHKIIH-TGKQPYKC 364
Query: 404 SLCSKQLFNAAALKNHVRAH--HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLD 461
CSK N +AL+ H H +P + E G+ + L + + H EE
Sbjct: 365 EECSKAFSNFSALRKHEIIHTGEKPYK-CEECGKAFKWSSKLTVHKVIHMEE-------- 415
Query: 462 HRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHC-KAA 518
+P KC ECG+A++H +L H+ H TG+ Y+C C + + N L H +H K
Sbjct: 416 -KPCKCEECGKAFKHFSALRKHKIIH-TGKKPYKCEECGKAFNNSSTLMKHKIIHTGKKP 473
Query: 519 RRSADIG-AEGAPSHLKVELPPDPVEAEAAPHT-DQDHVCKHEEEATDITPAADK----- 571
+ + G A SHL A HT ++ + C+ +A + A K
Sbjct: 474 YKCEECGKAFKQSSHL---------TRHKAIHTGEKPYKCEECGKAFNHFSALRKHQIIH 524
Query: 572 --TAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHS 629
+ C CG F + +L +H + H GEK + C +CGK+++ S
Sbjct: 525 TGKKPYKCEECGKAFSQSSTLRKHEIIH-TGEK-------------PYKCEECGKAFKWS 570
Query: 630 GSLINHRQTH-QTGDFSCGACAKHFHTMAAMKNHLRRHSRRR 670
L H+ H + + C C K F+ +A++ H H+ ++
Sbjct: 571 SHLTRHKVIHTEEKPYKCEECGKAFNHFSALRKHKIIHTGKK 612
Score = 140 bits (354), Expect = 9e-33
Identities = 95/350 (27%), Positives = 161/350 (46%), Gaps = 46/350 (13%)
Query: 1044 LLEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNH 1101
++ +P++C +CGK ++ L H+ IH TG+ + C C + + + +A R H H
Sbjct: 186 IIHTGKKPYKCEECGKAFKQSSHLTRHKAIH-TGEKPYKCEECGKAFNHFSALRKHQIIH 244
Query: 1102 PRCKGSEPQVGPIPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPL 1161
G +P E G + Q + + ++ H E+ E K L
Sbjct: 245 T---GKKPYKC---EECGKAFSQSSTLRK---HEIIHTEEKPYKYEECGKAFSNLSALRK 295
Query: 1162 EEVARVKEEVWE-ETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLIN 1220
E+ ++ ++ E K + +L T K T +E+P CE CG+++K +L
Sbjct: 296 HEIIHTGQKPYKCEECGKAFKWSSKL-TVHKVIHT---AEKPCKCEECGKAFKRFSALRK 351
Query: 1221 HRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQR 1278
H+ H TG + C+ CSK FSN +L+ H IH + ++C ECGKAF+ +L H+
Sbjct: 352 HKIIH-TGKQPYKCEECSKAFSNFSALRKHEIIHTGEKPYKCEECGKAFKWSSKLTVHKV 410
Query: 1279 VHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYS 1336
+HM E++P +C +CG+ ++H +L H+ H TG+ Y C C K ++
Sbjct: 411 IHM-------------EEKPCKCEECGKAFKHFSALRKHKIIH-TGKKPYKCEECGKAFN 456
Query: 1337 NRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREH 1386
N L H+ +H+ + +C CG++F L RH H
Sbjct: 457 NSSTLMKHKIIHTGKK----------PYKCEECGKAFKQSSHLTRHKAIH 496
Score = 139 bits (350), Expect = 3e-32
Identities = 179/800 (22%), Positives = 303/800 (37%), Gaps = 114/800 (14%)
Query: 235 EERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRP 293
EE+ YK +CGK + + +L H HT Y C C K F L H +H +P
Sbjct: 274 EEKPYKYEECGKAFSNLSALRKHEIIHTGQKPYKCEECGKAFKWSSKLTVHKVIHTAEKP 333
Query: 294 YHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNG---------HTDESSQDQ 344
C C + F+ L +H+ H G +Q + EE +N HT E
Sbjct: 334 CKCEECGKAFKRFSALRKHKIIHTG-KQPYKCEECSKAFSNFSALRKHEIIHTGEKPYKC 392
Query: 345 LPSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYP 402
+ S++L+ + E +P +C +CG+ ++H +L H+ H TG Y
Sbjct: 393 EECGKAFKWSSKLTVHKVIH----MEEKPCKCEECGKAFKHFSALRKHKIIH-TGKKPYK 447
Query: 403 CSLCSKQLFNAAALKNHVRAH-HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLD 461
C C K N++ L H H + E G+ + L + H E
Sbjct: 448 CEECGKAFNNSSTLMKHKIIHTGKKPYKCEECGKAFKQSSHLTRHKAIHTGE-------- 499
Query: 462 HRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHC-KAA 518
+PYKC ECG+A+ H +L H+ H TG+ Y+C C + + LR H +H +
Sbjct: 500 -KPYKCEECGKAFNHFSALRKHQIIH-TGKKPYKCEECGKAFSQSSTLRKHEIIHTGEKP 557
Query: 519 RRSADIG-AEGAPSHL------KVELPPDPVEAEAAPHTDQDHVCKHEEEATDITPAADK 571
+ + G A SHL E P E + KH+ T P
Sbjct: 558 YKCEECGKAFKWSSHLTRHKVIHTEEKPYKCEECGKAFNHFSALRKHKIIHTGKKP---- 613
Query: 572 TAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGS 631
+ C CG F + +L +H + H GEK + C +CGK+++ S
Sbjct: 614 ---YKCEECGKAFSQSSTLRKHEIIH-TGEK-------------PYKCEECGKAFKWSSK 656
Query: 632 LINHRQTHQT-GDFSCGACAKHFHTMAAMKNHLRRHSRRRSRRHR---KRAGGASGGREA 687
L H+ H C C K F +A++ H H+ ++ + K +S R+
Sbjct: 657 LTVHKVIHTAEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNNSSTLRKH 716
Query: 688 KLLAAESWTRELEDNEGLESPQDPSGESPHGAE--GNLESDGDCLQAES---------EG 736
+++ + + E+ + +G+ P+ E G ++ L+ +
Sbjct: 717 EIIHTGEKSYKCEECALRKHEIIHTGKKPYKCEECGKAFNNSSTLRKHKIIYTGKKPYKC 776
Query: 737 DKCG--------LERDETHFQGDK--ESGGTGEGLERKDASLLDNLDIPGEEGGGTHFCD 786
++CG L R + G+K + G G+ L H +
Sbjct: 777 EECGKAFKQSSHLTRHKAVHTGEKPYKCGECGKAFNNSSTLKKHKL---------IHTRE 827
Query: 787 SLTGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHTCSDCGHSFPHATGLLSHRPCHP-P 845
+E K + H TG + C +CG +F +++ L+ H+ H
Sbjct: 828 KSYKCEECGKAFSNFSALRKHKI-IHTGEKPYKCEEC-ECGKAFNNSSTLMKHKIIHTGE 885
Query: 846 GIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHRRQAHS 905
Y+C C K F++ L H H T +P+ C CG F + H+
Sbjct: 886 KPYKCEECGKGFNNFSTLMKHKIIH-----TGEKPYKCEECGKAFKQSSHLTKHK----- 935
Query: 906 SSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSAGYGHICGCCGQ 965
S T + EE G A + +R L++ +++ ++ + + + C CG+
Sbjct: 936 -SIHTGEKPYKCEERGKAFSHFSR-----LTKHRIIHTGKKPYKC-EECEKPYKCEECGK 988
Query: 966 TYDDLGSLERHHQSQSSGTT 985
++ L +H + G T
Sbjct: 989 AFNQSSHLTQHKTIHTGGKT 1008
Score = 123 bits (308), Expect = 2e-27
Identities = 117/565 (20%), Positives = 206/565 (36%), Gaps = 77/565 (13%)
Query: 1258 FRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNH 1317
F+C++ K F ++ +H ++ P++C +CG+ ++ + L H
Sbjct: 166 FQCNKYVKVFHKYSNSNRYKIIHTGKK-------------PYKCEECGKAFKQSSHLTRH 212
Query: 1318 RRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPG 1375
+ H TG+ Y C C K +++ AL+ HQ +H+ + +C CG++F
Sbjct: 213 KAIH-TGEKPYKCEECGKAFNHFSALRKHQIIHTGKK----------PYKCEECGKAFSQ 261
Query: 1376 RGSLER----HLREHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGG--------- 1422
+L + H E E L E TG + + + G
Sbjct: 262 SSTLRKHEIIHTEEKPYKYEECGKAFSNLSALRKHEIIHTGQKPYKCEECGKAFKWSSKL 321
Query: 1423 -AEPVPHLEDGVPRPGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQ 1481
V H + + E ++ R ++ + + G N S +
Sbjct: 322 TVHKVIHTAEKPCKCEECGKAFKRFSALRKHKIIHTGKQPYKCEECSKAFSNFSALRKHE 381
Query: 1482 FLTRSEEPEDSVHRSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHSSCSQCGKTYC 1541
+ E+P +L + HM+ C +CGK +
Sbjct: 382 IIHTGEKPYKCEECGKAFKWSSKLTVHKVIHMEE-------------KPCKCEECGKAFK 428
Query: 1542 QSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQE 1599
+L H T + + C C K F N H H + + C +CGKAF+
Sbjct: 429 HFSALRKHKIIHTGKKPYKCEECGKAFNNSSTLMKHKIIHTGKKPYKCEECGKAFKQSSH 488
Query: 1600 LASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQ--------GKAQEAPS----- 1646
L H H + +A + + + Q++ G+ GKA S
Sbjct: 489 LTRHKAIHTGEKPYKCEECGKAFNHFSALRKHQIIHTGKKPYKCEECGKAFSQSSTLRKH 548
Query: 1647 ------ETPRGPGESVERARGGQAVTS-MAAEDKERPFRCTQCGRSYRHAGSLLNHQKAH 1699
E P E + + +T +E+P++C +CG+++ H +L H+ H
Sbjct: 549 EIIHTGEKPYKCEECGKAFKWSSHLTRHKVIHTEEKPYKCEECGKAFNHFSALRKHKIIH 608
Query: 1700 TTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPRE 1758
T Y C C K +L+ H HT K + C CGKAF+ +++L H +H E
Sbjct: 609 TGKKPYKCEECGKAFSQSSTLRKHEIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHT-AE 667
Query: 1759 GPFTCPHCPRHFRRRISFVQHQQQH 1783
P C C + F+ + +H+ H
Sbjct: 668 KPCKCEECGKAFKHFSALRKHKIIH 692
Score = 110 bits (276), Expect = 1e-23
Identities = 102/443 (23%), Positives = 180/443 (40%), Gaps = 75/443 (16%)
Query: 245 GKTYKHAGSLTNHRQSHTLG-IYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVF 303
GK ++ A + N + T G I+ C K F + +H +PY C C + F
Sbjct: 144 GKMHEEAYNKLNQCWTTTQGKIFQCNKYVKVFHKYSNSNRYKIIHTGKKPYKCEECGKAF 203
Query: 304 RLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSGEL 363
+ L H+ H GE+ + EE G + L Q+++
Sbjct: 204 KQSSHLTRHKAIHTGEKPY-KCEECGKAFNH-------FSALRKHQIIHTGK-------- 247
Query: 364 EDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSH-QTGVYPCSLCSKQLFNAAALKNHVRA 422
+P++C +CG+ + + +L H H + Y C K N +AL+ H
Sbjct: 248 --------KPYKCEECGKAFSQSSTLRKHEIIHTEEKPYKYEECGKAFSNLSALRKHEII 299
Query: 423 H--HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSL 480
H +P + E G+ + L + + H E +P KC ECG+A++ +L
Sbjct: 300 HTGQKPYK-CEECGKAFKWSSKLTVHKVIHTAE---------KPCKCEECGKAFKRFSAL 349
Query: 481 VNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVH-------CKAARRSADIGAEGAPS 531
H+ H TG+ Y+C C + + N ALR H +H C+ ++ ++
Sbjct: 350 RKHKIIH-TGKQPYKCEECSKAFSNFSALRKHEIIHTGEKPYKCEECGKAFKWSSK-LTV 407
Query: 532 HLKVELPPDPVEAEAAPHTDQ--DHVCKHEEEATDITPAADKTAAHICSICGLLFEDAES 589
H + + P + E + + KH+ T P + C CG F ++ +
Sbjct: 408 HKVIHMEEKPCKCEECGKAFKHFSALRKHKIIHTGKKP-------YKCEECGKAFNNSST 460
Query: 590 LERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCG 647
L +H + H G+K + C +CGK+++ S L H+ H TG+ + C
Sbjct: 461 LMKHKIIH-TGKK-------------PYKCEECGKAFKQSSHLTRHKAIH-TGEKPYKCE 505
Query: 648 ACAKHFHTMAAMKNHLRRHSRRR 670
C K F+ +A++ H H+ ++
Sbjct: 506 ECGKAFNHFSALRKHQIIHTGKK 528
Score = 103 bits (257), Expect = 2e-21
Identities = 68/258 (26%), Positives = 110/258 (42%), Gaps = 14/258 (5%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C +CGK + + +L H T + + C CSK F N A + H H + + C +C
Sbjct: 336 CEECGKAFKRFSALRKHKIIHTGKQPYKCEECSKAFSNFSALRKHEIIHTGEKPYKCEEC 395
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDP-KAGTGEDQVVLPGQGKAQEAPSETP 1649
GKAF+ +L H H + P + EE K + + + GK E
Sbjct: 396 GKAFKWSSKLTVHKVIHME---EKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECG 452
Query: 1650 RGPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSL 1708
+ S + ++P++C +CG++++ + L H+ HT Y C
Sbjct: 453 KAFNNS------STLMKHKIIHTGKKPYKCEECGKAFKQSSHLTRHKAIHTGEKPYKCEE 506
Query: 1709 CPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPR 1768
C K + +L+ H HT K + C CGKAF ++ L H +H E P+ C C +
Sbjct: 507 CGKAFNHFSALRKHQIIHTGKKPYKCEECGKAFSQSSTLRKHEIIHTG-EKPYKCEECGK 565
Query: 1769 HFRRRISFVQHQQQHQEE 1786
F+ +H+ H EE
Sbjct: 566 AFKWSSHLTRHKVIHTEE 583
Score = 101 bits (252), Expect = 6e-21
Identities = 55/200 (27%), Positives = 97/200 (48%), Gaps = 31/200 (15%)
Query: 1198 SSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADP 1255
+ ++P+ CE CG+++K + L H+ H TG + C+ C K F++ +L+ H+ IH
Sbjct: 189 TGKKPYKCEECGKAFKQSSHLTRHKAIH-TGEKPYKCEECGKAFNHFSALRKHQIIHTGK 247
Query: 1256 RRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLL 1315
+ ++C ECGKAF L H+ +H E++P++ +CG+ + + +L
Sbjct: 248 KPYKCEECGKAFSQSSTLRKHEIIH-------------TEEKPYKYEECGKAFSNLSALR 294
Query: 1316 NHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSF 1373
H H TGQ Y C C K + L H+ +H+ + +C CG++F
Sbjct: 295 KHEIIH-TGQKPYKCEECGKAFKWSSKLTVHKVIHTAEK----------PCKCEECGKAF 343
Query: 1374 PGRGSLERHLREHEETEREP 1393
+L +H H T ++P
Sbjct: 344 KRFSALRKHKIIH--TGKQP 361
Score = 99.8 bits (247), Expect = 2e-20
Identities = 71/271 (26%), Positives = 111/271 (40%), Gaps = 18/271 (6%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDRHYCLL--CSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C +CGK + S L H T C C K F + A + H H + + C +C
Sbjct: 644 CEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEEC 703
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSE--- 1647
GKAF + L H H S + + TG+ GKA S
Sbjct: 704 GKAFNNSSTLRKHEIIHTGEKSYKCEECALRKHEIIHTGKKPYKCEECGKAFNNSSTLRK 763
Query: 1648 -----TPRGPGESVERARGGQAVTSM----AAEDKERPFRCTQCGRSYRHAGSLLNHQKA 1698
T + P + E + + + + A E+P++C +CG+++ ++ +L H+
Sbjct: 764 HKIIYTGKKPYKCEECGKAFKQSSHLTRHKAVHTGEKPYKCGECGKAFNNSSTLKKHKLI 823
Query: 1699 HT-TGLYPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCS--ICGKAFRTAARLEGHGRVHA 1755
HT Y C C K N +L+ H HT K + C CGKAF ++ L H +H
Sbjct: 824 HTREKSYKCEECGKAFSNFSALRKHKIIHTGEKPYKCEECECGKAFNNSSTLMKHKIIHT 883
Query: 1756 PREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
E P+ C C + F + ++H+ H E
Sbjct: 884 -GEKPYKCEECGKGFNNFSTLMKHKIIHTGE 913
Score = 97.4 bits (241), Expect = 1e-19
Identities = 64/262 (24%), Positives = 102/262 (38%), Gaps = 17/262 (6%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C +CGK + S +L H T + + C C K F H H + + C +C
Sbjct: 748 CEECGKAFNNSSTLRKHKIIYTGKKPYKCEECGKAFKQSSHLTRHKAVHTGEKPYKCGEC 807
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPR 1650
GKAF + L H H R S + +A + + +++ G+ + E +
Sbjct: 808 GKAFNNSSTLKKHKLIHTREKSYKCEECGKAFSNFSALRKHKIIHTGEKPYKCEECECGK 867
Query: 1651 GPGESVERARGGQAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLC 1709
S + E+P++C +CG+ + + +L+ H+ HT Y C C
Sbjct: 868 AFNNS------STLMKHKIIHTGEKPYKCEECGKGFNNFSTLMKHKIIHTGEKPYKCEEC 921
Query: 1710 PKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPR--------EGPF 1761
K L H HT K + C GKAF +RL H +H + E P+
Sbjct: 922 GKAFKQSSHLTKHKSIHTGEKPYKCEERGKAFSHFSRLTKHRIIHTGKKPYKCEECEKPY 981
Query: 1762 TCPHCPRHFRRRISFVQHQQQH 1783
C C + F + QH+ H
Sbjct: 982 KCEECGKAFNQSSHLTQHKTIH 1003
Score = 89.0 bits (219), Expect = 4e-17
Identities = 67/260 (25%), Positives = 102/260 (39%), Gaps = 30/260 (11%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C +CGK + QS L H T + C C K F + A + H H + + C +C
Sbjct: 476 CEECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSALRKHQIIHTGKKPYKCEEC 535
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEA-----------RDPKAGTGEDQVVLPGQG 1639
GKAF L H H + P + EE R T E G
Sbjct: 536 GKAFSQSSTLRKHEIIHT---GEKPYKCEECGKAFKWSSHLTRHKVIHTEEKPYKCEECG 592
Query: 1640 KAQEAPS--------ETPRGPGESVERARGGQAVTSMAAED----KERPFRCTQCGRSYR 1687
KA S T + P + E + +++ + E+P++C +CG++++
Sbjct: 593 KAFNHFSALRKHKIIHTGKKPYKCEECGKAFSQSSTLRKHEIIHTGEKPYKCEECGKAFK 652
Query: 1688 HAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAAR 1746
+ L H+ HT C C K + +L+ H HT K + C CGKAF ++
Sbjct: 653 WSSKLTVHKVIHTAEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNNSST 712
Query: 1747 LEGHGRVHAPREGPFTCPHC 1766
L H +H E + C C
Sbjct: 713 LRKHEIIHT-GEKSYKCEEC 731
Score = 84.0 bits (206), Expect = 1e-15
Identities = 64/266 (24%), Positives = 95/266 (35%), Gaps = 54/266 (20%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C +CGK + QS L H T + C C K F N K H H +++ C +C
Sbjct: 776 CEECGKAFKQSSHLTRHKAVHTGEKPYKCGECGKAFNNSSTLKKHKLIHTREKSYKCEEC 835
Query: 1591 GKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPR 1650
GKAF + L H H + P + EE KA ++ + T
Sbjct: 836 GKAFSNFSALRKHKIIHT---GEKPYKCEECECGKAFNNSSTLM-------KHKIIHTGE 885
Query: 1651 GPGESVERARGGQAVTSMAAED----KERPFRCTQCGRSYRHAGSLLNHQKAHT------ 1700
P + E +G +++ E+P++C +CG++++ + L H+ HT
Sbjct: 886 KPYKCEECGKGFNNFSTLMKHKIIHTGEKPYKCEECGKAFKQSSHLTKHKSIHTGEKPYK 945
Query: 1701 ---------------------TGL-----------YPCSLCPKLLPNLLSLKNHSRTHTD 1728
TG Y C C K L H HT
Sbjct: 946 CEERGKAFSHFSRLTKHRIIHTGKKPYKCEECEKPYKCEECGKAFNQSSHLTQHKTIHTG 1005
Query: 1729 PKRHCCSICGKAFRTAARLEGHGRVH 1754
K + C CGKAF + L H +H
Sbjct: 1006 GKTYKCEECGKAFNHLSALTKHKIIH 1031
Score = 80.1 bits (196), Expect = 2e-14
Identities = 51/233 (21%), Positives = 98/233 (42%), Gaps = 27/233 (11%)
Query: 1153 QEELKVEPLEEVARVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSY 1212
+ E+ +P + ++ W + ++K E L T + + G+ +
Sbjct: 88 RHEMVTKPPVISSHFTQDFWPDQSIKDSFQEIILRTYARCGHKNLRLRKDCESVNEGKMH 147
Query: 1213 KHAGSLINHRQSHQTGH-FGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRK 1271
+ A + +N + G F C K F + ++ IH + ++C ECGKAF+
Sbjct: 148 EEAYNKLNQCWTTTQGKIFQCNKYVKVFHKYSNSNRYKIIHTGKKPYKCEECGKAFKQSS 207
Query: 1272 QLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCP 1329
L H+ +H ++P++C +CG+ + H +L H+ H TG+ Y C
Sbjct: 208 HLTRHKAIH-------------TGEKPYKCEECGKAFNHFSALRKHQIIH-TGKKPYKCE 253
Query: 1330 TCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERH 1382
C K +S L+ H+ +H+E + + CG++F +L +H
Sbjct: 254 ECGKAFSQSSTLRKHEIIHTEEK----------PYKYEECGKAFSNLSALRKH 296
Score = 77.0 bits (188), Expect = 2e-13
Identities = 54/229 (23%), Positives = 94/229 (41%), Gaps = 22/229 (9%)
Query: 1579 HIDAQTFACPDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQ 1638
H + + C +CGKAF+ L H H + +A + + + Q++ G+
Sbjct: 188 HTGKKPYKCEECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSALRKHQIIHTGK 247
Query: 1639 --------GKAQEAPS-----ETPRGPGESVERARGGQAVTSMAAEDK-------ERPFR 1678
GKA S E + + G+A ++++A K ++P++
Sbjct: 248 KPYKCEECGKAFSQSSTLRKHEIIHTEEKPYKYEECGKAFSNLSALRKHEIIHTGQKPYK 307
Query: 1679 CTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSIC 1737
C +CG++++ + L H+ HT C C K +L+ H HT + + C C
Sbjct: 308 CEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGKAFKRFSALRKHKIIHTGKQPYKCEEC 367
Query: 1738 GKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
KAF + L H +H E P+ C C + F+ H+ H EE
Sbjct: 368 SKAFSNFSALRKHEIIHT-GEKPYKCEECGKAFKWSSKLTVHKVIHMEE 415
Score = 77.0 bits (188), Expect = 2e-13
Identities = 69/299 (23%), Positives = 114/299 (38%), Gaps = 53/299 (17%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C + F L+RH+ + + +PY+C +CG+ + + +L H+
Sbjct: 776 CEECGKAFKQSSHLTRHKAV------------HTGEKPYKCGECGKAFNNSSTLKKHKLI 823
Query: 70 H-ETGLFPCTTCGKDFSNPMALKSHMRTHAPEGRRR-----------HRPPRPKEATPHL 117
H + C CGK FSN AL+ H H E + + K H
Sbjct: 824 HTREKSYKCEECGKAFSNFSALRKHKIIHTGEKPYKCEECECGKAFNNSSTLMKHKIIHT 883
Query: 118 QGETVSTDSWGQRLGS-SEGWENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQREGLA 175
+ + G+ + S +++ HT E P CE +Q L
Sbjct: 884 GEKPYKCEECGKGFNNFSTLMKHKIIHTGEKPYKCEECGKA-----------FKQSSHLT 932
Query: 176 SHPGPEDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEE 235
H S ++ P S+ + +++ G++P + E
Sbjct: 933 KHK-----------SIHTGEKPYKCEERGKAFSHFSRLTKHRIIHT--GKKPYKCE--EC 977
Query: 236 ERRYKCSQCGKTYKHAGSLTNHRQSHTLG-IYPCAICFKEFSNLMALKNHSRLHAQYRP 293
E+ YKC +CGK + + LT H+ HT G Y C C K F++L AL H +H +P
Sbjct: 978 EKPYKCEECGKAFNQSSHLTQHKTIHTGGKTYKCEECGKAFNHLSALTKHKIIHTGEKP 1036
Score = 55.8 bits (133), Expect = 4e-07
Identities = 30/95 (31%), Positives = 40/95 (42%), Gaps = 10/95 (10%)
Query: 236 ERRYKCSQCGKTYKHAGSLTNHRQSHT----------LGIYPCAICFKEFSNLMALKNHS 285
E+ YKC + GK + H LT HR HT Y C C K F+ L H
Sbjct: 941 EKPYKCEERGKAFSHFSRLTKHRIIHTGKKPYKCEECEKPYKCEECGKAFNQSSHLTQHK 1000
Query: 286 RLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGER 320
+H + Y C C + F L +H+ H GE+
Sbjct: 1001 TIHTGGKTYKCEECGKAFNHLSALTKHKIIHTGEK 1035
Score = 54.3 bits (129), Expect = 1e-06
Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 4/112 (3%)
Query: 1677 FRCTQCGRSYRHAGSLLNHQKAHTTGL--YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCC 1734
F+C + + + H S N K TG Y C C K L H HT K + C
Sbjct: 166 FQCNKYVKVF-HKYSNSNRYKIIHTGKKPYKCEECGKAFKQSSHLTRHKAIHTGEKPYKC 224
Query: 1735 SICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
CGKAF + L H +H ++ P+ C C + F + + +H+ H EE
Sbjct: 225 EECGKAFNHFSALRKHQIIHTGKK-PYKCEECGKAFSQSSTLRKHEIIHTEE 275
Score = 47.8 bits (112), Expect = 1e-04
Identities = 28/102 (27%), Positives = 46/102 (45%), Gaps = 2/102 (1%)
Query: 1683 GRSYRHAGSLLNHQKAHTTG-LYPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAF 1741
G+ + A + LN T G ++ C+ K+ + + HT K + C CGKAF
Sbjct: 144 GKMHEEAYNKLNQCWTTTQGKIFQCNKYVKVFHKYSNSNRYKIIHTGKKPYKCEECGKAF 203
Query: 1742 RTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQH 1783
+ ++ L H +H E P+ C C + F + +HQ H
Sbjct: 204 KQSSHLTRHKAIHT-GEKPYKCEECGKAFNHFSALRKHQIIH 244
Score = 47.8 bits (112), Expect = 1e-04
Identities = 29/114 (25%), Positives = 47/114 (41%), Gaps = 21/114 (18%)
Query: 7 SLSCSDCQRHFPSLPELSRHRELLHPSPNQDSEEAD------------------SIPRPY 48
S C +C + F + L +H+ + EE + + +PY
Sbjct: 829 SYKCEECGKAFSNFSALRKHKIIHTGEKPYKCEECECGKAFNNSSTLMKHKIIHTGEKPY 888
Query: 49 RCQQCGRGYRHPGSLVNHRRTHETGLFP--CTTCGKDFSNPMALKSHMRTHAPE 100
+C++CG+G+ + +L+ H+ H TG P C CGK F L H H E
Sbjct: 889 KCEECGKGFNNFSTLMKHKIIH-TGEKPYKCEECGKAFKQSSHLTKHKSIHTGE 941
>gi|24432013 zinc finger protein 668 [Homo sapiens]
Length = 619
Score = 172 bits (435), Expect = 4e-42
Identities = 167/624 (26%), Positives = 240/624 (38%), Gaps = 111/624 (17%)
Query: 1162 EEVARVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINH 1221
EEVA VK + ET K EE + EK A+ RP++C +C ++YK A L +H
Sbjct: 51 EEVAEVKPK--PETEAKAEEA-----SGEK-VSGSAAKPRPYACPLCPKAYKTAPELRSH 102
Query: 1222 RQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRV 1279
+SH TG F C C + F + L+ H HA FRC+ C KA+ +L HQR
Sbjct: 103 GRSH-TGEKPFPCPECGRRFMQPVCLRVHLASHAGELPFRCAHCPKAYGALSKLKIHQRG 161
Query: 1280 HMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRSHE-TGQYSCPTCPKTYSNR 1338
H +RP+ C CG+++ HRR+H YSC C K Y+
Sbjct: 162 HTG-------------ERPYACADCGKSFADPSVFRKHRRTHAGLRPYSCERCGKAYAEL 208
Query: 1339 MALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREH--EETEREPANG 1396
L++H+R H+ R C+ CG+SF SL H R H ++ R PA G
Sbjct: 209 KDLRNHERSHTGER----------PFLCSECGKSFSRSSSLTCHQRIHAAQKPYRCPACG 258
Query: 1397 QGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRPGERSQSP--IRAASSEAPEP 1454
+G L+ Q E G +P PR G P R E
Sbjct: 259 KGF--------TQLSSYQSHERTHSGEKPFL-----CPRCGRMFSDPSSFRRHQRAHEEV 305
Query: 1455 LSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSPCHAGD----CQLNGPTL 1510
+ K G +P D H GD C T
Sbjct: 306 KPYHCEKCG--------------------KDFRQPADLAMHRRVHTGDRPFKCLQCDKTF 345
Query: 1511 SHMDSWDNRDNSSQLQPGSHSSCSQCGKTYCQSGSLLNHNTNKTDRH--YCLLCSKEFLN 1568
+ SWD + ++ C +CG+ + + SL H+ + +C C K F+
Sbjct: 346 --VASWDLKRHALVHSGQRPFRCEECGRAFAERASLTKHSRVHSGERPFHCNACGKSFVV 403
Query: 1569 PVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAH---ARGHSQVPAQMEEARDPK 1625
+ + H H ++ P QEL L A S PA DP
Sbjct: 404 SSSLRKHERTHRSSEAAGVPPA-------QELVVGLALPVGVAGESSAAPAAGAGLGDPP 456
Query: 1626 AGT----GEDQVVLPGQGKA----------QEAPSETPRGPGESVERARGGQAVTSMAAE 1671
AG E V+ Q + Q+A GP E A G +A +
Sbjct: 457 AGLLGLPPESGGVMATQWQVVGMTVEHVECQDAGVREAPGPLEGAGEAGGEEA------D 510
Query: 1672 DKERPFRCTQCGRSYRHAGSLLNHQKAHTT-GLYPCSLCPKLLPNLLSLKNHSRTHTDPK 1730
+K F C +C ++ L H+++H +PC+ C K + L+ HSRTH+ +
Sbjct: 511 EKPPQFVCRECKETFSTMTLLRRHERSHPELRPFPCTQCGKSFSDRAGLRKHSRTHSSVR 570
Query: 1731 RHCCSICGKAFRTAARLEGHGRVH 1754
+ C C KAF +A+ L H R H
Sbjct: 571 PYTCPHCPKAFLSASDLRKHERTH 594
Score = 160 bits (405), Expect = 1e-38
Identities = 151/593 (25%), Positives = 220/593 (37%), Gaps = 84/593 (14%)
Query: 1079 FLCPVCSRCYPNLAAYRNHLRNH--PRCKGSEPQVGPIPEAAGSSELQVGPIPEGGSNKP 1136
+ C C++ +PN H H C +V P PE +E G G + KP
Sbjct: 22 YKCLSCTKTFPNAPRAARHAATHGPADCSEEVAEVKPKPETEAKAEEASGEKVSGSAAKP 81
Query: 1137 QHMAEEGPGQAEVEKLQEELKVE----------PLEEVAR-VKEEVWEETTVKGEEIEPR 1185
+ A P + K EL+ P E R + V + E
Sbjct: 82 RPYA--CPLCPKAYKTAPELRSHGRSHTGEKPFPCPECGRRFMQPVCLRVHLASHAGELP 139
Query: 1186 LETAE-----------KGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQ-TGHFGCQ 1233
A K Q + ERP++C CG+S+ HR++H + C+
Sbjct: 140 FRCAHCPKAYGALSKLKIHQRGHTGERPYACADCGKSFADPSVFRKHRRTHAGLRPYSCE 199
Query: 1234 ACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERR-------GG 1286
C K ++ L L+NH R H R F CSECGK+F L HQR+H ++ G
Sbjct: 200 RCGKAYAELKDLRNHERSHTGERPFLCSECGKSFSRSSSLTCHQRIHAAQKPYRCPACGK 259
Query: 1287 GGTRKATRE--------DRPFRCGQCGRTYRHAGSLLNHRRSH-ETGQYSCPTCPKTYSN 1337
G T+ ++ + ++PF C +CGR + S H+R+H E Y C C K +
Sbjct: 260 GFTQLSSYQSHERTHSGEKPFLCPRCGRMFSDPSSFRRHQRAHEEVKPYHCEKCGKDFRQ 319
Query: 1338 RMALKDHQRLHSENR------------------RRRAGRSRRTAVRCALCGRSFPGRGSL 1379
L H+R+H+ +R R S + RC CGR+F R SL
Sbjct: 320 PADLAMHRRVHTGDRPFKCLQCDKTFVASWDLKRHALVHSGQRPFRCEECGRAFAERASL 379
Query: 1380 ERHLREHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRPGER 1439
+H R H ER G +S ++ G P L G+ P
Sbjct: 380 TKHSRVH-SGERPFHCNACGKSFVVSSSLRKHERTHRSSEAAGVPPAQELVVGLALP--- 435
Query: 1440 SQSPIRAASSEAPEPLSWGAGKAGGWPVGG--GLGNHSGGWVPQFLTRSEEPEDSVHRSP 1497
+ SS AP AG G P G GL SGG T+ + +V
Sbjct: 436 --VGVAGESSAAP-----AAGAGLGDPPAGLLGLPPESGG---VMATQWQVVGMTVEHVE 485
Query: 1498 CH-AGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHSSCSQCGKTYCQSGSLLNHNTNKTDR 1556
C AG + GP ++ + C +C +T+ L H + +
Sbjct: 486 CQDAGVREAPGP----LEGAGEAGGEEADEKPPQFVCRECKETFSTMTLLRRHERSHPEL 541
Query: 1557 H--YCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAH 1607
C C K F + + HS H + + CP C KAF S +L H + H
Sbjct: 542 RPFPCTQCGKSFSDRAGLRKHSRTHSSVRPYTCPHCPKAFLSASDLRKHERTH 594
Score = 148 bits (373), Expect = 5e-35
Identities = 169/723 (23%), Positives = 245/723 (33%), Gaps = 154/723 (21%)
Query: 237 RRYKCSQCGKTYKHAGSLTNHRQSHTLGIYPCAICFKEFSNLMAL------------KNH 284
RRYKC C KT+ +A H +H A C +E + + +
Sbjct: 20 RRYKCLSCTKTFPNAPRAARHAATHGP-----ADCSEEVAEVKPKPETEAKAEEASGEKV 74
Query: 285 SRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQEPRWE---EKGMPTTNGHTDESS 341
S A+ RPY CP CP+ ++ EL H +SH GE+ P E P S
Sbjct: 75 SGSAAKPRPYACPLCPKAYKTAPELRSHGRSHTGEKPFPCPECGRRFMQPVCLRVHLASH 134
Query: 342 QDQLP--SAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQ-T 398
+LP A LS ++ G RP+ C DCG+++ HR++H
Sbjct: 135 AGELPFRCAHCPKAYGALSKL-KIHQRGHTGERPYACADCGKSFADPSVFRKHRRTHAGL 193
Query: 399 GVYPCSLCSKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTT 458
Y C C K L+NH R+H GE
Sbjct: 194 RPYSCERCGKAYAELKDLRNHERSH------TGE-------------------------- 221
Query: 459 TLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE-YQCSLCPRKYPNLMALRNHVRVHC-- 515
RP+ CSECG+++ SL H+ H + Y+C C + + L + ++H R H
Sbjct: 222 ----RPFLCSECGKSFSRSSSLTCHQRIHAAQKPYRCPACGKGFTQLSSYQSHERTHSGE 277
Query: 516 ------KAARRSADIGAEGAPSHLKVELPPDPVEAEAAPHTDQDHVCKHEEEATDITPAA 569
+ R +D + E+ P E + H T P
Sbjct: 278 KPFLCPRCGRMFSDPSSFRRHQRAHEEVKPYHCEKCGKDFRQPADLAMHRRVHTGDRPFK 337
Query: 570 DKTAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHS 629
C C F + L+RH L H S R F C +CG+++
Sbjct: 338 -------CLQCDKTFVASWDLKRHALVH--------------SGQRPFRCEECGRAFAER 376
Query: 630 GSLINHRQTHQ-TGDFSCGACAKHFHTMAAMKNHLRRHSRRRSRRHRKRAGGASGGREAK 688
SL H + H F C AC K F ++++ H R H R+ A+G A+
Sbjct: 377 ASLTKHSRVHSGERPFHCNACGKSFVVSSSLRKHERTH----------RSSEAAGVPPAQ 426
Query: 689 LLAAESWTRELEDNEGLESPQDPS--GESPHGAEGNLESDGDCLQAESEGDKCGLERDET 746
L E +P + G+ P G G G + + + +E E
Sbjct: 427 ELVVGLALPVGVAGESSAAPAAGAGLGDPPAGLLGLPPESGGVMATQWQVVGMTVEHVEC 486
Query: 747 HFQGDKESGGTGEGLERKDASLLDNLDIPGEEGGGTHFCDSLTGVDEDQKPATGQPNSSS 806
G +E+ G EG GE G G + D+KP
Sbjct: 487 QDAGVREAPGPLEG--------------AGEAG----------GEEADEKP--------- 513
Query: 807 HSANAVTGWQAGAAHTCSDCGHSFPHATGLLSHRPCHPP-GIYQCSLCPKEFDSLPALRS 865
C +C +F T L H HP + C+ C K F LR
Sbjct: 514 ------------PQFVCRECKETFSTMTLLRRHERSHPELRPFPCTQCGKSFSDRAGLRK 561
Query: 866 HFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEA 925
H + H +S +P+ C C F + R H R G E G+ E
Sbjct: 562 HSRTH-----SSVRPYTCPHCPKAFLSASDLRKHERTHPVPMGTPTPLEPLVALLGMPEE 616
Query: 926 APA 928
PA
Sbjct: 617 GPA 619
Score = 145 bits (367), Expect = 3e-34
Identities = 131/460 (28%), Positives = 186/460 (40%), Gaps = 51/460 (11%)
Query: 236 ERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPY 294
E ++C+ C K Y L H++ HT Y CA C K F++ + H R HA RPY
Sbjct: 137 ELPFRCAHCPKAYGALSKLKIHQRGHTGERPYACADCGKSFADPSVFRKHRRTHAGLRPY 196
Query: 295 HCPHCPRVFRLPRELLEHQQSHEGER-----QEPRWEEKGMPTTNGHTDESSQDQLPSAQ 349
C C + + ++L H++SH GER + + + T ++Q
Sbjct: 197 SCERCGKAYAELKDLRNHERSHTGERPFLCSECGKSFSRSSSLTCHQRIHAAQKPYRCPA 256
Query: 350 MLNGSAELST--SGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSH-QTGVYPCSLC 406
G +LS+ S E SG +PF C CGR + S H+++H + Y C C
Sbjct: 257 CGKGFTQLSSYQSHERTHSG---EKPFLCPRCGRMFSDPSSFRRHQRAHEEVKPYHCEKC 313
Query: 407 SKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEED-PTTTLDH--- 462
K A L H R H R P L + T D L H
Sbjct: 314 GKDFRQPADLAMHRRVHTGDR------------PFKCLQCDKTFVASWDLKRHALVHSGQ 361
Query: 463 RPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHCKAARR 520
RP++C ECGRA+ R SL H H +GE + C+ C + + +LR H R H R
Sbjct: 362 RPFRCEECGRAFAERASLTKHSRVH-SGERPFHCNACGKSFVVSSSLRKHERTH-----R 415
Query: 521 SADIGAEGAPSHLKVELPPDPV----EAEAAPHTDQDHVCKHEEEATDITPAADKTAAHI 576
S++ L V L PV E+ AAP + + P + A
Sbjct: 416 SSEAAGVPPAQELVVGLAL-PVGVAGESSAAPAAGAG-LGDPPAGLLGLPPESGGVMATQ 473
Query: 577 CSICGLLFE-----DAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGS 631
+ G+ E DA E G GAGE E PP+ F CR+C +++
Sbjct: 474 WQVVGMTVEHVECQDAGVREAPGPLEGAGEAGGE--EADEKPPQ-FVCRECKETFSTMTL 530
Query: 632 LINHRQTH-QTGDFSCGACAKHFHTMAAMKNHLRRHSRRR 670
L H ++H + F C C K F A ++ H R HS R
Sbjct: 531 LRRHERSHPELRPFPCTQCGKSFSDRAGLRKHSRTHSSVR 570
Score = 126 bits (317), Expect = 2e-28
Identities = 125/518 (24%), Positives = 185/518 (35%), Gaps = 108/518 (20%)
Query: 821 HTCSDCGHSFPHATGLLSHRPCHPPGI--YQCSLCPKEFDSLPALRSHFQNHRPGEATSA 878
+ C+DCG SF + HR H G+ Y C C K + L LR+H ++H T
Sbjct: 168 YACADCGKSFADPSVFRKHRRTHA-GLRPYSCERCGKAYAELKDLRNHERSH-----TGE 221
Query: 879 QPFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEA 938
+PFLC CG F + H+R H++ P R P
Sbjct: 222 RPFLCSECGKSFSRSSSLTCHQR-IHAAQ------------------KPYRCPACGKGFT 262
Query: 939 ELLNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGD 998
+L + E S +C CG+ + D S RH ++ + P G
Sbjct: 263 QLSSYQSHE--RTHSGEKPFLCPRCGRMFSDPSSFRRHQRAHE-----EVKPYHCEKCGK 315
Query: 999 AMEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGES-----------LLEA 1047
D + V++ GD + C+Q ++ L+ +
Sbjct: 316 DFRQPADLAMHRRVHT-----GDRPFK-----------CLQCDKTFVASWDLKRHALVHS 359
Query: 1048 QPRPFRCNQCGKTYRHGGSLVNHRKIHQ-TGDFLCPVCSRCYPNLAAYRNHLRNHPRCKG 1106
RPFRC +CG+ + SL H ++H F C C + + ++ R H R H
Sbjct: 360 GQRPFRCEECGRAFAERASLTKHSRVHSGERPFHCNACGKSFVVSSSLRKHERTH----- 414
Query: 1107 SEPQVGPIPEAAGSSELQVG---PIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEE 1163
+ +P A EL VG P+ G + A G G L + P E
Sbjct: 415 RSSEAAGVPPA---QELVVGLALPVGVAGESSAAPAAGAGLGDPPAGLLG----LPP--E 465
Query: 1164 VARVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQ 1223
V W+ + E +E CQ E P E AG
Sbjct: 466 SGGVMATQWQVVGMTVEHVE---------CQDAGVREAPGPLE-------GAGEAGGEEA 509
Query: 1224 SHQTGHFGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMER 1283
+ F C+ C + FS + L+ H R H + R F C++CGK+F R L H R H
Sbjct: 510 DEKPPQFVCRECKETFSTMTLLRRHERSHPELRPFPCTQCGKSFSDRAGLRKHSRTH--- 566
Query: 1284 RGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRSH 1321
RP+ C C + + A L H R+H
Sbjct: 567 ----------SSVRPYTCPHCPKAFLSASDLRKHERTH 594
Score = 114 bits (284), Expect = 1e-24
Identities = 147/640 (22%), Positives = 219/640 (34%), Gaps = 126/640 (19%)
Query: 1256 RRFRCSECGKAFRLRKQLASHQRVH---------------------MERRGGGGTRKATR 1294
RR++C C K F + A H H E G +
Sbjct: 20 RRYKCLSCTKTFPNAPRAARHAATHGPADCSEEVAEVKPKPETEAKAEEASGEKVSGSAA 79
Query: 1295 EDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLH---- 1348
+ RP+ C C + Y+ A L +H RSH TG+ + CP C + + + L+ H H
Sbjct: 80 KPRPYACPLCPKAYKTAPELRSHGRSH-TGEKPFPCPECGRRFMQPVCLRVHLASHAGEL 138
Query: 1349 --------------SENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHEETEREPA 1394
S+ + + G + CA CG+SF +H R H
Sbjct: 139 PFRCAHCPKAYGALSKLKIHQRGHTGERPYACADCGKSFADPSVFRKHRRTHAGLRPYSC 198
Query: 1395 NGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRPGERSQSPIRAASSEAPEP 1454
G + A L + E G P E G +S R++S +
Sbjct: 199 ERCG------KAYAELKDLRNHERSHTGERPFLCSECG--------KSFSRSSSLTCHQR 244
Query: 1455 LSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSPCHAGD----CQLNGPTL 1510
+ A K P G G+ +S E H+G+ C G
Sbjct: 245 IH-AAQKPYRCPACG------KGFTQLSSYQSHE--------RTHSGEKPFLCPRCGRMF 289
Query: 1511 SHMDSWDNRDNS-SQLQPGSHSSCSQCGKTYCQSGSLLNHNTNKT-DRHY-CLLCSKEFL 1567
S S+ + +++P C GK + Q L H T DR + CL C K F+
Sbjct: 290 SDPSSFRRHQRAHEEVKPYHCEKC---GKDFRQPADLAMHRRVHTGDRPFKCLQCDKTFV 346
Query: 1568 NPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHA------------------- 1608
K H+ H + F C +CG+AF L H + H+
Sbjct: 347 ASWDLKRHALVHSGQRPFRCEECGRAFAERASLTKHSRVHSGERPFHCNACGKSFVVSSS 406
Query: 1609 -RGHSQVPAQMEEARDPKAGTGEDQVVLP--GQGKAQEAPS------ETPRG----PGES 1655
R H + E A P A + LP G++ AP+ + P G P ES
Sbjct: 407 LRKHERTHRSSEAAGVPPAQELVVGLALPVGVAGESSAAPAAGAGLGDPPAGLLGLPPES 466
Query: 1656 VERARGGQAVTSMAAEDKERPFRCTQCG-----RSYRHAGSLLNHQKAHTTGLYPCSLCP 1710
V M E E C G AG + + C C
Sbjct: 467 GGVMATQWQVVGMTVEHVE----CQDAGVREAPGPLEGAGEAGGEEADEKPPQFVCRECK 522
Query: 1711 KLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHF 1770
+ + L+ H R+H + + C+ CGK+F A L H R H+ P+TCPHCP+ F
Sbjct: 523 ETFSTMTLLRRHERSHPELRPFPCTQCGKSFSDRAGLRKHSRTHSSVR-PYTCPHCPKAF 581
Query: 1771 RRRISFVQHQQQHQEEWTVAGSGAPVAPVTGRGDLPLPPP 1810
+H++ H G+ P+ P+ +P P
Sbjct: 582 LSASDLRKHERTHP---VPMGTPTPLEPLVALLGMPEEGP 618
Score = 108 bits (269), Expect = 6e-23
Identities = 142/645 (22%), Positives = 202/645 (31%), Gaps = 169/645 (26%)
Query: 816 QAGAAHTCSDCGHSFPHATGLLSHRPCHPPG----------------------------- 846
++G + C C +FP+A H H P
Sbjct: 17 RSGRRYKCLSCTKTFPNAPRAARHAATHGPADCSEEVAEVKPKPETEAKAEEASGEKVSG 76
Query: 847 ------IYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHR 900
Y C LCPK + + P LRSH ++H T +PF C CG F R+H
Sbjct: 77 SAAKPRPYACPLCPKAYKTAPELRSHGRSH-----TGEKPFPCPECGRRFMQPVCLRVHL 131
Query: 901 ---------RQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEAL 951
R AH S+ + + G P
Sbjct: 132 ASHAGELPFRCAHCPKAYGALSKLKIHQRGHTGERP------------------------ 167
Query: 952 DSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDI 1011
+ C CG+++ D +H + T A P G A + D L +
Sbjct: 168 ------YACADCGKSFADPSVFRKHRR-----THAGLRPYSCERCGKAYAELKD--LRNH 214
Query: 1012 VNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYRHGGSLVNHR 1071
S +GE S+ G SL + A +P+RC CGK + S +H
Sbjct: 215 ERSHTGERPFLCSECGKSFSRSSSLTC---HQRIHAAQKPYRCPACGKGFTQLSSYQSHE 271
Query: 1072 KIHQ-TGDFLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAAGSSELQVGPIPE 1130
+ H FLCP C R + + +++R H R H
Sbjct: 272 RTHSGEKPFLCPRCGRMFSDPSSFRRHQRAHEEV-------------------------- 305
Query: 1131 GGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKEEVWEETTVKGEEIEPRLETAE 1190
KP H + G + L +V + + + ++T V +++ R
Sbjct: 306 ----KPYHCEKCGKDFRQPADLAMHRRVHTGDRPFKCLQ--CDKTFVASWDLK-RHALVH 358
Query: 1191 KGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH-FGCQACSKGFSNLMSLKNHR 1249
G +RPF CE CGR++ SL H + H F C AC K F SL+ H
Sbjct: 359 SG-------QRPFRCEECGRAFAERASLTKHSRVHSGERPFHCNACGKSFVVSSSLRKHE 411
Query: 1250 RIHADPRRF---RCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCG---- 1302
R H E L +A G G A P G
Sbjct: 412 RTHRSSEAAGVPPAQELVVGLALPVGVAGESSAAPAAGAGLGDPPAGLLGLPPESGGVMA 471
Query: 1303 ----QCGRTYRH-----------------AGSLLNHRRSHETGQYSCPTCPKTYSNRMAL 1341
G T H AG + Q+ C C +T+S L
Sbjct: 472 TQWQVVGMTVEHVECQDAGVREAPGPLEGAGEAGGEEADEKPPQFVCRECKETFSTMTLL 531
Query: 1342 KDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREH 1386
+ H+R H E R C CG+SF R L +H R H
Sbjct: 532 RRHERSHPELR----------PFPCTQCGKSFSDRAGLRKHSRTH 566
Score = 107 bits (267), Expect = 1e-22
Identities = 154/681 (22%), Positives = 228/681 (33%), Gaps = 161/681 (23%)
Query: 10 CSDCQRHFPSLPELSRHREL------------LHPSPNQDS--EEAD--------SIPRP 47
C C + FP+ P +RH + P P ++ EEA + PRP
Sbjct: 24 CLSCTKTFPNAPRAARHAATHGPADCSEEVAEVKPKPETEAKAEEASGEKVSGSAAKPRP 83
Query: 48 YRCQQCGRGYRHPGSLVNHRRTHETGL--FPCTTCGKDFSNPMALKSHMRTHAPE--GRR 103
Y C C + Y+ L +H R+H TG FPC CG+ F P+ L+ H+ +HA E R
Sbjct: 84 YACPLCPKAYKTAPELRSHGRSH-TGEKPFPCPECGRRFMQPVCLRVHLASHAGELPFRC 142
Query: 104 RHRPP---RPKEATPHLQGET-----VSTDSWGQRLGSSEGWENQTKHTEETP-DCESVP 154
H P + H +G T D S +++ H P CE
Sbjct: 143 AHCPKAYGALSKLKIHQRGHTGERPYACADCGKSFADPSVFRKHRRTHAGLRPYSCERC- 201
Query: 155 DPRAASGTWEDLPTRQREGLASHP--GPEDGADGWGPSTNS------ARAPPLPIPASSL 206
A +DL +R P E G S+ + A P PA
Sbjct: 202 --GKAYAELKDLRNHERSHTGERPFLCSECGKSFSRSSSLTCHQRIHAAQKPYRCPACGK 259
Query: 207 -LSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSH-TLG 264
+ L Y +S G++P P +CG+ + S H+++H +
Sbjct: 260 GFTQLSSY--QSHERTHSGEKPFLCP-----------RCGRMFSDPSSFRRHQRAHEEVK 306
Query: 265 IYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQEPR 324
Y C C K+F L H R+H RP+ C C + F +L H H G+R
Sbjct: 307 PYHCEKCGKDFRQPADLAMHRRVHTGDRPFKCLQCDKTFVASWDLKRHALVHSGQR---- 362
Query: 325 WEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYR 384
PFRC +CGR +
Sbjct: 363 ------------------------------------------------PFRCEECGRAFA 374
Query: 385 HAGSLINHRKSHQTGVYP--CSLCSKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAP 442
SL H + H +G P C+ C K +++L+ H R HR + G VPPA
Sbjct: 375 ERASLTKHSRVH-SGERPFHCNACGKSFVVSSSLRKHERT-HRSSEAAG------VPPAQ 426
Query: 443 LLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGEYQCSLCPRKYP 502
L+ P + A G+ + + G P +
Sbjct: 427 ELVVGLA-------------LPVGVAGESSAAPAAGAGLGDPPAGLLG------LPPESG 467
Query: 503 NLMALRNHVRVHCKAARRSADIGAEGAPSHLKVELPPDPVEAEAAPHTDQDHVCKHEEEA 562
+MA + V D G AP L+ EA+ P CK
Sbjct: 468 GVMATQWQVVGMTVEHVECQDAGVREAPGPLEGAGEAGGEEADEKPPQFVCRECKETFST 527
Query: 563 TDITPAADKTAAHI----CSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFA 618
+ +++ + C+ CG F D L +H TH S R +
Sbjct: 528 MTLLRRHERSHPELRPFPCTQCGKSFSDRAGLRKHSRTH--------------SSVRPYT 573
Query: 619 CRDCGKSYRHSGSLINHRQTH 639
C C K++ + L H +TH
Sbjct: 574 CPHCPKAFLSASDLRKHERTH 594
Score = 107 bits (267), Expect = 1e-22
Identities = 137/572 (23%), Positives = 196/572 (34%), Gaps = 120/572 (20%)
Query: 5 PPSLSCSDCQRHFPSLPELSRH----------------RELLHPSPNQDSEEADSIPRPY 48
P +C C + + + PEL H R + P + + + P+
Sbjct: 81 PRPYACPLCPKAYKTAPELRSHGRSHTGEKPFPCPECGRRFMQPVCLRVHLASHAGELPF 140
Query: 49 RCQQCGRGYRHPGSLVNHRRTHETGLFP--CTTCGKDFSNPMALKSHMRTHAPEGRRRHR 106
RC C + Y L H+R H TG P C CGK F++P + H RT H
Sbjct: 141 RCAHCPKAYGALSKLKIHQRGH-TGERPYACADCGKSFADPSVFRKHRRT--------HA 191
Query: 107 PPRPKEATPHLQGETVSTDSWGQRLGSSEGWENQTK-HTEETPD-CESVPDPRAASGTWE 164
RP S + G+ + N + HT E P C + S +
Sbjct: 192 GLRP-----------YSCERCGKAYAELKDLRNHERSHTGERPFLCSECGKSFSRSSS-- 238
Query: 165 DLPTRQREGLASHPGPEDGADGWG----------PSTNSARAPPLPIPASSLLSNLEQYL 214
L QR A P A G G T+S P L + S+ +
Sbjct: 239 -LTCHQRIHAAQKPY-RCPACGKGFTQLSSYQSHERTHSGEKPFLCPRCGRMFSDPSSFR 296
Query: 215 AESVVNFTGGQEPTQSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSHTLGIYP--CAICF 272
+ EE + Y C +CGK ++ L HR+ HT G P C C
Sbjct: 297 RHQRAH-------------EEVKPYHCEKCGKDFRQPADLAMHRRVHT-GDRPFKCLQCD 342
Query: 273 KEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQ------EPRWE 326
K F LK H+ +H+ RP+ C C R F L +H + H GER +
Sbjct: 343 KTFVASWDLKRHALVHSGQRPFRCEECGRAFAERASLTKHSRVHSGERPFHCNACGKSFV 402
Query: 327 EKGMPTTNGHTDESSQDQ-LPSAQML------------NGSAELSTSGELED--SGLEEY 371
+ T SS+ +P AQ L SA + L D +GL
Sbjct: 403 VSSSLRKHERTHRSSEAAGVPPAQELVVGLALPVGVAGESSAAPAAGAGLGDPPAGLLGL 462
Query: 372 RPFRCGDCGRTYRHAGSLINHRKSHQTGVYPCSLCSKQLFNAAALKNHVRAHHRPRQGVG 431
P G ++ G + H + GV R P +G G
Sbjct: 463 PPESGGVMATQWQVVGMTVEHVECQDAGV--------------------REAPGPLEGAG 502
Query: 432 ENGQPSVPPAPLLLAETTHKEEEDPTTTL--------DHRPYKCSECGRAYRHRGSLVNH 483
E G P KE T L + RP+ C++CG+++ R L H
Sbjct: 503 EAGGEEADEKPPQFVCRECKETFSTMTLLRRHERSHPELRPFPCTQCGKSFSDRAGLRKH 562
Query: 484 RHSHRTGE-YQCSLCPRKYPNLMALRNHVRVH 514
+H + Y C CP+ + + LR H R H
Sbjct: 563 SRTHSSVRPYTCPHCPKAFLSASDLRKHERTH 594
Score = 95.9 bits (237), Expect = 3e-19
Identities = 147/679 (21%), Positives = 226/679 (33%), Gaps = 133/679 (19%)
Query: 492 YQCSLCPRKYPNLMALRNHVRVHCKAARRSADIGAEGAPSHLKVELPPDPVEAEAAPHTD 551
Y+C C + +PN H H AD E A E+ P P E EA
Sbjct: 22 YKCLSCTKTFPNAPRAARHAATH-----GPADCSEEVA------EVKPKP-ETEAKAE-- 67
Query: 552 QDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTETTM 611
E ++ +A K + C +C ++ A L HG +H GEK
Sbjct: 68 -------EASGEKVSGSAAKPRPYACPLCPKAYKTAPELRSHGRSH-TGEKP-------- 111
Query: 612 SPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHSRR 669
F C +CG+ + L H +H G+ F C C K + ++ +K H R H+
Sbjct: 112 -----FPCPECGRRFMQPVCLRVHLASH-AGELPFRCAHCPKAYGALSKLKIHQRGHTGE 165
Query: 670 RS----------------RRHRKRAGGASGGREAKLLAAESWTRELEDNEGLESPQDPSG 713
R R+HR+ G + A + ++L ++E + + P
Sbjct: 166 RPYACADCGKSFADPSVFRKHRRTHAGLRPYSCERCGKAYAELKDLRNHERSHTGERPFL 225
Query: 714 ESPHGAEGNLESDGDCLQAESEGDKCGLERDETHFQGDKESGGTGEGLERKDASLLDNLD 773
S G + S C Q K G+G + +
Sbjct: 226 CSECGKSFSRSSSLTCHQRIHAAQK------------PYRCPACGKGFTQLSSYQSHERT 273
Query: 774 IPGEEGGGTHFCDSLTGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHTCSDCGHSFPHA 833
GE+ C + D P++ + + +H + + C CG F
Sbjct: 274 HSGEK---PFLCPRCGRMFSD--PSSFRRHQRAH--------EEVKPYHCEKCGKDFRQP 320
Query: 834 TGLLSHRPCHPPGI-YQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPG 892
L HR H ++C C K F + L+ H H + +PF C CG F
Sbjct: 321 ADLAMHRRVHTGDRPFKCLQCDKTFVASWDLKRHALVH-----SGQRPFRCEECGRAFAE 375
Query: 893 RAGYRLHRRQAHSSS----------GMTEGSEEEGEEEGVAEAAPARSPPLQ--LSEAEL 940
RA H R HS S E + A PP Q + L
Sbjct: 376 RASLTKHSR-VHSGERPFHCNACGKSFVVSSSLRKHERTHRSSEAAGVPPAQELVVGLAL 434
Query: 941 LNQLQREVEALDSAGYG-------------HICGCCGQTYDDLGSLERHHQSQSSGTTAD 987
+ E A +AG G G + +G H + Q +G
Sbjct: 435 PVGVAGESSAAPAAGAGLGDPPAGLLGLPPESGGVMATQWQVVGMTVEHVECQDAGVR-- 492
Query: 988 KAPSPLGVAGDAMEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDS---LCIQGGESL 1044
+AP PL AG+A GE D K + ++ + +
Sbjct: 493 EAPGPLEGAGEA----------------GGEEADEKPPQFVCRECKETFSTMTLLRRHER 536
Query: 1045 LEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQT-GDFLCPVCSRCYPNLAAYRNHLRNHPR 1103
+ RPF C QCGK++ L H + H + + CP C + + + + R H R HP
Sbjct: 537 SHPELRPFPCTQCGKSFSDRAGLRKHSRTHSSVRPYTCPHCPKAFLSASDLRKHERTHPV 596
Query: 1104 CKGSEPQVGPIPEAAGSSE 1122
G+ + P+ G E
Sbjct: 597 PMGTPTPLEPLVALLGMPE 615
Score = 91.3 bits (225), Expect = 8e-18
Identities = 97/437 (22%), Positives = 158/437 (36%), Gaps = 66/437 (15%)
Query: 1354 RRAGRSRRTAVRCALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASEANLTGS 1413
+R+GR +C C ++FP RH H + + + +EA +
Sbjct: 16 KRSGRR----YKCLSCTKTFPNAPRAARHAATHGPADCSEEVAE--VKPKPETEAKAEEA 69
Query: 1414 QGLETQLGGAEPVPHLEDGVPRPGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGN 1473
G + A+P P+ P+ A APE S G G P
Sbjct: 70 SGEKVSGSAAKPRPYACPLCPK-----------AYKTAPELRSHGRSHTGEKPFP----- 113
Query: 1474 HSGGWVPQFLTRSEEPEDSVHRSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHS-- 1531
P+ R +P HAG+ +H + ++ H+
Sbjct: 114 -----CPECGRRFMQPVCLRVHLASHAGELPFR---CAHCPKAYGALSKLKIHQRGHTGE 165
Query: 1532 ---SCSQCGKTYCQSGSLLNHN-TNKTDRHY-CLLCSKEFLNPVATKSHSHNHIDAQTFA 1586
+C+ CGK++ H T+ R Y C C K + ++H +H + F
Sbjct: 166 RPYACADCGKSFADPSVFRKHRRTHAGLRPYSCERCGKAYAELKDLRNHERSHTGERPFL 225
Query: 1587 CPDCGKAFESHQELASHLQAHA-----------RGHSQVPAQMEEARDPKAGTGEDQVVL 1635
C +CGK+F L H + HA +G +Q+ + R +GE +
Sbjct: 226 CSECGKSFSRSSSLTCHQRIHAAQKPYRCPACGKGFTQLSSYQSHER---THSGEKPFLC 282
Query: 1636 PGQGKAQEAPSETPRG--------PGESVERARGGQAVTSMAAEDK----ERPFRCTQCG 1683
P G+ PS R P + + + +A + +RPF+C QC
Sbjct: 283 PRCGRMFSDPSSFRRHQRAHEEVKPYHCEKCGKDFRQPADLAMHRRVHTGDRPFKCLQCD 342
Query: 1684 RSYRHAGSLLNHQKAHTTGLYP--CSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAF 1741
+++ + L H H+ G P C C + SL HSR H+ + C+ CGK+F
Sbjct: 343 KTFVASWDLKRHALVHS-GQRPFRCEECGRAFAERASLTKHSRVHSGERPFHCNACGKSF 401
Query: 1742 RTAARLEGHGRVHAPRE 1758
++ L H R H E
Sbjct: 402 VVSSSLRKHERTHRSSE 418
Score = 55.8 bits (133), Expect = 4e-07
Identities = 31/97 (31%), Positives = 44/97 (45%), Gaps = 13/97 (13%)
Query: 2 EDTPPSLSCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPG 61
++ PP C +C+ F ++ L RH E HP RP+ C QCG+ +
Sbjct: 510 DEKPPQFVCRECKETFSTMTLLRRH-ERSHPEL-----------RPFPCTQCGKSFSDRA 557
Query: 62 SLVNHRRTHET-GLFPCTTCGKDFSNPMALKSHMRTH 97
L H RTH + + C C K F + L+ H RTH
Sbjct: 558 GLRKHSRTHSSVRPYTCPHCPKAFLSASDLRKHERTH 594
>gi|74027276 zinc finger protein 226 isoform a [Homo sapiens]
Length = 803
Score = 171 bits (434), Expect = 5e-42
Identities = 148/585 (25%), Positives = 235/585 (40%), Gaps = 110/585 (18%)
Query: 1198 SSERPFSCEVCGRSYKHAGSLINHRQSHQTGHFGCQACSKGFSNLMSLKNHRRIHADPRR 1257
S E+ +C G+ + ++ L H++ H C C K FS L+ H+++H +
Sbjct: 275 SGEKSLTCVERGKGFCYSPVLPVHQKVHVGEKLKCDECGKEFSQGAHLQTHQKVHVIEKP 334
Query: 1258 FRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNH 1317
++C +CGK F R L H +VH ++P+ C +CGR + A L +H
Sbjct: 335 YKCKQCGKGFSRRSALNVHCKVHTA-------------EKPYNCEECGRAFSQASHLQDH 381
Query: 1318 RRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPG 1375
+R H TG+ + C C K++S L+ HQR+H+ + +C CG+ F
Sbjct: 382 QRLH-TGEKPFKCDACGKSFSRNSHLQSHQRVHTGEK----------PYKCEECGKGFIC 430
Query: 1376 RGSLERHLREH--EETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGV 1433
+L H R H E+ + G+G + ++L QG+ T
Sbjct: 431 SSNLYIHQRVHTGEKPYKCEECGKG-----FSRPSSLQAHQGVHT--------------- 470
Query: 1434 PRPGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSV 1493
GE+S + GK G+ + L H + + E S
Sbjct: 471 ---GEKSY-------------ICTVCGK--GFTLSSNLQAHQRVHTGEKPYKCNECGKSF 512
Query: 1494 HRSP-------CHAGD----CQLNGPTLSHMDSWDNRDNSSQLQPGSHS-----SCSQCG 1537
R+ H G+ C++ G S + + Q+ +HS C +CG
Sbjct: 513 RRNSHYQVHLVVHTGEKPYKCEICGKGFS-------QSSYLQIHQKAHSIEKPFKCEECG 565
Query: 1538 KTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFE 1595
+ + QS L H T + C C K F K H H + + C +CGK F
Sbjct: 566 QGFNQSSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFR 625
Query: 1596 SHQELASHLQAHARGHS-QVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGE 1654
AS+L AH R HS + P + EE + Q T P +
Sbjct: 626 Q----ASNLLAHQRVHSGEKPFKCEECGKSFGRSAHLQA---------HQKVHTGDKPYK 672
Query: 1655 SVERARGGQAVTSMAAEDK----ERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLC 1709
E +G + ++ + E+P++C +CG+ + A SL HQ HT Y C +C
Sbjct: 673 CDECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKYFSQASSLQLHQSVHTGEKPYKCDVC 732
Query: 1710 PKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVH 1754
K+ L++H R HT K + C ICGK+F + L H R+H
Sbjct: 733 GKVFSRSSQLQSHQRVHTGEKPYKCEICGKSFSWRSNLTVHHRIH 777
Score = 169 bits (429), Expect = 2e-41
Identities = 157/602 (26%), Positives = 240/602 (39%), Gaps = 102/602 (16%)
Query: 1220 NHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQ 1277
+H TG + C C K FS+L S H+++ + + C E GK F L HQ
Sbjct: 240 DHNSMIHTGQKSYQCNECKKPFSDLSSFDLHQQLQSGEKSLTCVERGKGFCYSPVLPVHQ 299
Query: 1278 RVHM---------ERRGGGGTRKATRE-----DRPFRCGQCGRTYRHAGSLLNHRRSHET 1323
+VH+ + G T + ++P++C QCG+ + +L H + H
Sbjct: 300 KVHVGEKLKCDECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGFSRRSALNVHCKVHTA 359
Query: 1324 GQ-YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERH 1382
+ Y+C C + +S L+DHQRLH+ + +C CG+SF L+ H
Sbjct: 360 EKPYNCEECGRAFSQASHLQDHQRLHTGEK----------PFKCDACGKSFSRNSHLQSH 409
Query: 1383 LREHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRPGERSQS 1442
R H T +P + G S +NL Q + T G +P E G G S
Sbjct: 410 QRVH--TGEKPYKCEECGKGFICS-SNLYIHQRVHT---GEKPYKCEECG---KGFSRPS 460
Query: 1443 PIRAASSEAPEPLSWGAGKAG-GWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSP---- 1497
++A S+ G G+ + L H + + E S R+
Sbjct: 461 SLQAHQGVHTGEKSYICTVCGKGFTLSSNLQAHQRVHTGEKPYKCNECGKSFRRNSHYQV 520
Query: 1498 ---CHAGD----CQLNGPTLSHMDSWDNRDNSSQLQPGSHS-----SCSQCGKTYCQSGS 1545
H G+ C++ G S + + Q+ +HS C +CG+ + QS
Sbjct: 521 HLVVHTGEKPYKCEICGKGFS-------QSSYLQIHQKAHSIEKPFKCEECGQGFNQSSR 573
Query: 1546 LLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASH 1603
L H T + C C K F K H H + + C +CGK F AS+
Sbjct: 574 LQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQ----ASN 629
Query: 1604 LQAHARGHS-QVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVERARGG 1662
L AH R HS + P + EE G+S R+
Sbjct: 630 LLAHQRVHSGEKPFKCEEC-------------------------------GKSFGRSAHL 658
Query: 1663 QAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLCPKLLPNLLSLKN 1721
QA + DK P++C +CG+ ++ + +L HQ+ HT Y C C K SL+
Sbjct: 659 QAHQKVHTGDK--PYKCDECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKYFSQASSLQL 716
Query: 1722 HSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQ 1781
H HT K + C +CGK F +++L+ H RVH E P+ C C + F R + H +
Sbjct: 717 HQSVHTGEKPYKCDVCGKVFSRSSQLQSHQRVHT-GEKPYKCEICGKSFSWRSNLTVHHR 775
Query: 1782 QH 1783
H
Sbjct: 776 IH 777
Score = 159 bits (402), Expect = 2e-38
Identities = 152/584 (26%), Positives = 240/584 (41%), Gaps = 82/584 (14%)
Query: 822 TCSDCGHSFPHATGLLSHRPCHPPGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPF 881
TC + G F ++ L H+ H +C C KEF L++H + H +P+
Sbjct: 281 TCVERGKGFCYSPVLPVHQKVHVGEKLKCDECGKEFSQGAHLQTHQKVH-----VIEKPY 335
Query: 882 LCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELL 941
C CG F R+ +H + H T EE G A S+A L
Sbjct: 336 KCKQCGKGFSRRSALNVHCK-VH-----TAEKPYNCEECGRA-----------FSQASHL 378
Query: 942 NQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAME 1001
QR L + C CG+++ S H QS T +K P G
Sbjct: 379 QDHQR----LHTGEKPFKCDACGKSF----SRNSHLQSHQRVHTGEK-PYKCEECGKGFI 429
Query: 1002 MVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTY 1061
+ + V+ +GE + G G SL G + + + C CGK +
Sbjct: 430 CSSNLYIHQRVH--TGEKPYKCEECGKGFSRPSSLQAHQG---VHTGEKSYICTVCGKGF 484
Query: 1062 RHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPI--PEA 1117
+L H+++H TG+ + C C + + + Y+ HL H G +P I
Sbjct: 485 TLSSNLQAHQRVH-TGEKPYKCNECGKSFRRNSHYQVHLVVH---TGEKPYKCEICGKGF 540
Query: 1118 AGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKEEVWEETTV 1177
+ SS LQ+ KP E G G + +LQ + E+ + +E +
Sbjct: 541 SQSSYLQIHQ-KAHSIEKPFKCEECGQGFNQSSRLQIHQLIHTGEKPYKCEECGKGFSRR 599
Query: 1178 KGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQ-TGHFGCQACS 1236
+I R+ T EK P++CE CG+ ++ A +L+ H++ H F C+ C
Sbjct: 600 ADLKIHCRIHTGEK----------PYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEECG 649
Query: 1237 KGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATRED 1296
K F L+ H+++H + ++C ECGK F+ L HQRVH +
Sbjct: 650 KSFGRSAHLQAHQKVHTGDKPYKCDECGKGFKWSLNLDMHQRVH-------------TGE 696
Query: 1297 RPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRR 1354
+P++CG+CG+ + A SL H+ H TG+ Y C C K +S L+ HQR+H+ +
Sbjct: 697 KPYKCGECGKYFSQASSLQLHQSVH-TGEKPYKCDVCGKVFSRSSQLQSHQRVHTGEK-- 753
Query: 1355 RAGRSRRTAVRCALCGRSFPGRGSLERHLREHEETEREPANGQG 1398
+C +CG+SF R +L H R H + +N G
Sbjct: 754 --------PYKCEICGKSFSWRSNLTVHHRIHVGDKSYKSNRGG 789
Score = 140 bits (354), Expect = 9e-33
Identities = 125/468 (26%), Positives = 192/468 (41%), Gaps = 61/468 (13%)
Query: 236 ERRYKCSQCGKTYKHAGSLTNHRQSHTLGIYP--CAICFKEFSNLMALKNHSRLHAQYRP 293
E+ Y C +CG+ + A L +H++ HT G P C C K FS L++H R+H +P
Sbjct: 360 EKPYNCEECGRAFSQASHLQDHQRLHT-GEKPFKCDACGKSFSRNSHLQSHQRVHTGEKP 418
Query: 294 YHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGM-----PTTNGHTDESSQDQLPSA 348
Y C C + F L HQ+ H GE+ + EE G + H + ++
Sbjct: 419 YKCEECGKGFICSSNLYIHQRVHTGEKPY-KCEECGKGFSRPSSLQAHQGVHTGEKSYIC 477
Query: 349 QMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTGV--YPCSLC 406
+ LS++ + +P++C +CG+++R H H TG Y C +C
Sbjct: 478 TVCGKGFTLSSNLQAHQRVHTGEKPYKCNECGKSFRRNSHYQVHLVVH-TGEKPYKCEIC 536
Query: 407 SKQLFNAAALKNHVRAHHRPRQGVGEN-GQPSVPPAPLLLAETTHKEEEDPTTTLDHRPY 465
K ++ L+ H +AH + E GQ + L + + H E +PY
Sbjct: 537 GKGFSQSSYLQIHQKAHSIEKPFKCEECGQGFNQSSRLQIHQLIHTGE---------KPY 587
Query: 466 KCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVH-------CK 516
KC ECG+ + R L H H TGE Y C C + + L H RVH C+
Sbjct: 588 KCEECGKGFSRRADLKIHCRIH-TGEKPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCE 646
Query: 517 AARRSADIGAEGAPSHLKVELPPDPVEAEAAPHTDQD--HVCKHEEEATDITPAADKTAA 574
+S A +H KV P + + + ++ H+ T P
Sbjct: 647 ECGKSFGRSAH-LQAHQKVHTGDKPYKCDECGKGFKWSLNLDMHQRVHTGEKP------- 698
Query: 575 HICSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLIN 634
+ C CG F A SL+ H H GEK + C CGK + S L +
Sbjct: 699 YKCGECGKYFSQASSLQLHQSVH-TGEKP-------------YKCDVCGKVFSRSSQLQS 744
Query: 635 HRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHSRRRSRRHRKRAGG 680
H++ H TG+ + C C K F + + H R H +S ++ GG
Sbjct: 745 HQRVH-TGEKPYKCEICGKSFSWRSNLTVHHRIHVGDKS--YKSNRGG 789
Score = 139 bits (351), Expect = 2e-32
Identities = 142/568 (25%), Positives = 223/568 (39%), Gaps = 102/568 (17%)
Query: 1242 LMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRC 1301
+++ ++ IH + ++C+EC K F HQ++ G + T C
Sbjct: 236 ILTFDHNSMIHTGQKSYQCNECKKPFSDLSSFDLHQQLQ------SGEKSLT-------C 282
Query: 1302 GQCGRTYRHAGSLLNHRRSHETGQYSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRR 1361
+ G+ + ++ L H++ H + C C K +S L+ HQ++H +
Sbjct: 283 VERGKGFCYSPVLPVHQKVHVGEKLKCDECGKEFSQGAHLQTHQKVHVIEK--------- 333
Query: 1362 TAVRCALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASEAN-LTGSQGLETQL 1420
+C CG+ F R +L H + H T +P N + G A S+A+ L Q L T
Sbjct: 334 -PYKCKQCGKGFSRRSALNVHCKVH--TAEKPYNCEEC--GRAFSQASHLQDHQRLHT-- 386
Query: 1421 GGAEPVPHLEDGVPRPGERS---QSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGG 1477
G +P D + R+ QS R + E P G G S
Sbjct: 387 -GEKPFKC--DACGKSFSRNSHLQSHQRVHTGEKPYKCE---------ECGKGFICSSNL 434
Query: 1478 WVPQFLTRSEEPEDSVHRSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHSS----- 1532
++ Q + E+P C+ G S R +S Q G H+
Sbjct: 435 YIHQRVHTGEKPYK-----------CEECGKGFS-------RPSSLQAHQGVHTGEKSYI 476
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C+ CGK + S +L H T + C C K F + H H + + C C
Sbjct: 477 CTVCGKGFTLSSNLQAHQRVHTGEKPYKCNECGKSFRRNSHYQVHLVVHTGEKPYKCEIC 536
Query: 1591 GKAFESHQELASHLQAHARGHS-QVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSE-- 1647
GK F +S+LQ H + HS + P + EE GQG Q + +
Sbjct: 537 GKGFSQ----SSYLQIHQKAHSIEKPFKCEEC---------------GQGFNQSSRLQIH 577
Query: 1648 ----TPRGPGESVERARGGQAVTSMAAEDK----ERPFRCTQCGRSYRHAGSLLNHQKAH 1699
T P + E +G + + E+P+ C +CG+ +R A +LL HQ+ H
Sbjct: 578 QLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVH 637
Query: 1700 TTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPRE 1758
+ + C C K L+ H + HT K + C CGK F+ + L+ H RVH E
Sbjct: 638 SGEKPFKCEECGKSFGRSAHLQAHQKVHTGDKPYKCDECGKGFKWSLNLDMHQRVHTG-E 696
Query: 1759 GPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
P+ C C ++F + S HQ H E
Sbjct: 697 KPYKCGECGKYFSQASSLQLHQSVHTGE 724
Score = 134 bits (338), Expect = 6e-31
Identities = 135/538 (25%), Positives = 210/538 (39%), Gaps = 98/538 (18%)
Query: 8 LSCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHR 67
L C +C + F L H+++ I +PY+C+QCG+G+ +L H
Sbjct: 307 LKCDECGKEFSQGAHLQTHQKV------------HVIEKPYKCKQCGKGFSRRSALNVHC 354
Query: 68 RTHETGL-FPCTTCGKDFSNPMALKSHMRTHAPE------------GRRRHRPPRPKEAT 114
+ H + C CG+ FS L+ H R H E R H +
Sbjct: 355 KVHTAEKPYNCEECGRAFSQASHLQDHQRLHTGEKPFKCDACGKSFSRNSHLQSHQR--- 411
Query: 115 PHLQGETVSTDSWGQR-LGSSEGWENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQRE 172
H + + G+ + SS + +Q HT E P CE G P+
Sbjct: 412 VHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKPYKCEE-------CGKGFSRPS---- 460
Query: 173 GLASHPGPEDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPP 232
L +H G G + + +L SNL+ + TG
Sbjct: 461 SLQAHQGVHTGEKSYICTVCG--------KGFTLSSNLQAHQRV----HTG--------- 499
Query: 233 AEEERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQY 291
E+ YKC++CGK+++ H HT Y C IC K FS L+ H + H+
Sbjct: 500 ---EKPYKCNECGKSFRRNSHYQVHLVVHTGEKPYKCEICGKGFSQSSYLQIHQKAHSIE 556
Query: 292 RPYHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNG---------HTDESSQ 342
+P+ C C + F L HQ H GE+ + EE G + HT E
Sbjct: 557 KPFKCEECGQGFNQSSRLQIHQLIHTGEKPY-KCEECGKGFSRRADLKIHCRIHTGEKPY 615
Query: 343 DQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--V 400
+ ++ ++ L + +PF+C +CG+++ + L H+K H TG
Sbjct: 616 NCEECGKVFRQASNLLAHQRVHSG----EKPFKCEECGKSFGRSAHLQAHQKVH-TGDKP 670
Query: 401 YPCSLCSKQLFNAAALKNHVRAH--HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTT 458
Y C C K + L H R H +P + GE G+ + L L ++ H E
Sbjct: 671 YKCDECGKGFKWSLNLDMHQRVHTGEKPYK-CGECGKYFSQASSLQLHQSVHTGE----- 724
Query: 459 TLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVH 514
+PYKC CG+ + L +H+ H TGE Y+C +C + + L H R+H
Sbjct: 725 ----KPYKCDVCGKVFSRSSQLQSHQRVH-TGEKPYKCEICGKSFSWRSNLTVHHRIH 777
Score = 130 bits (327), Expect = 1e-29
Identities = 150/657 (22%), Positives = 238/657 (36%), Gaps = 143/657 (21%)
Query: 7 SLSCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNH 66
S C++C++ F L H++L Q E++ C + G+G+ + L H
Sbjct: 251 SYQCNECKKPFSDLSSFDLHQQL------QSGEKS------LTCVERGKGFCYSPVLPVH 298
Query: 67 RRTHETGLFPCTTCGKDFSNPMALKSHMRTHAPEGRRR---------HRPPRPKEATPHL 117
++ H C CGK+FS L++H + H E + R H
Sbjct: 299 QKVHVGEKLKCDECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGFSRRSALNVHCKVHT 358
Query: 118 QGETVSTDSWGQRLG-SSEGWENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQREGLA 175
+ + + G+ +S ++Q HT E P C++ + + L + QR
Sbjct: 359 AEKPYNCEECGRAFSQASHLQDHQRLHTGEKPFKCDACGKSFSRN---SHLQSHQRVHTG 415
Query: 176 SHPGP-EDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAE 234
P E+ G+ S+N Y+ + V TG
Sbjct: 416 EKPYKCEECGKGFICSSN-------------------LYIHQRV--HTG----------- 443
Query: 235 EERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRP 293
E+ YKC +CGK + SL H+ HT Y C +C K F+ L+ H R+H +P
Sbjct: 444 -EKPYKCEECGKGFSRPSSLQAHQGVHTGEKSYICTVCGKGFTLSSNLQAHQRVHTGEKP 502
Query: 294 YHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNG 353
Y C C + FR H H GE+ ++
Sbjct: 503 YKCNECGKSFRRNSHYQVHLVVHTGEKPY------------------------KCEICGK 538
Query: 354 SAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLF 411
S+ ++ +PF+C +CG+ + + L H+ H TG Y C C K
Sbjct: 539 GFSQSSYLQIHQKAHSIEKPFKCEECGQGFNQSSRLQIHQLIH-TGEKPYKCEECGKGFS 597
Query: 412 NAAALKNHVRAHHRPR-QGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSEC 470
A LK H R H + E G+ + LL + H E +P+KC EC
Sbjct: 598 RRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVHSGE---------KPFKCEEC 648
Query: 471 GRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHCKAARRSADIGAEG 528
G+++ L H+ H TG+ Y+C C + + + L H RVH + G G
Sbjct: 649 GKSFGRSAHLQAHQKVH-TGDKPYKCDECGKGFKWSLNLDMHQRVH--TGEKPYKCGECG 705
Query: 529 APSHLKVELPPDPVEAEAAPHTDQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAE 588
K ++ + HT + + C +CG +F +
Sbjct: 706 -----KYFSQASSLQLHQSVHTGE--------------------KPYKCDVCGKVFSRSS 740
Query: 589 SLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGDFS 645
L+ H H GEK + C CGKS+ +L H + H GD S
Sbjct: 741 QLQSHQRVH-TGEK-------------PYKCEICGKSFSWRSNLTVHHRIH-VGDKS 782
Score = 119 bits (299), Expect = 2e-26
Identities = 144/624 (23%), Positives = 236/624 (37%), Gaps = 129/624 (20%)
Query: 1043 SLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGDFLCPVCSR----CY-PNLAAYRN- 1096
S++ + ++CN+C K + S H+++ Q+G+ R CY P L ++
Sbjct: 243 SMIHTGQKSYQCNECKKPFSDLSSFDLHQQL-QSGEKSLTCVERGKGFCYSPVLPVHQKV 301
Query: 1097 HLRNHPRCKGSEPQVGPIPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEEL 1156
H+ +C + ++ V KP + G G + L
Sbjct: 302 HVGEKLKCDECGKEFSQGAHLQTHQKVHV-------IEKPYKCKQCGKGFSRRSALNVHC 354
Query: 1157 KVEPLEEVARVKEEVWEETTVKGEEIEPRLETAEKGCQTEA------------------S 1198
KV E+ +E + + RL T EK + +A +
Sbjct: 355 KVHTAEKPYNCEECGRAFSQASHLQDHQRLHTGEKPFKCDACGKSFSRNSHLQSHQRVHT 414
Query: 1199 SERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPR 1256
E+P+ CE CG+ + + +L H++ H TG + C+ C KGFS SL+ H+ +H +
Sbjct: 415 GEKPYKCEECGKGFICSSNLYIHQRVH-TGEKPYKCEECGKGFSRPSSLQAHQGVHTGEK 473
Query: 1257 RFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLN 1316
+ C+ CGK F L L +HQRVH ++P++C +CG+++R
Sbjct: 474 SYICTVCGKGFTLSSNLQAHQRVH-------------TGEKPYKCNECGKSFRRNSHYQV 520
Query: 1317 HRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHS-------ENRRRRAGRSRRTAV--- 1364
H H TG+ Y C C K +S L+ HQ+ HS E + +S R +
Sbjct: 521 HLVVH-TGEKPYKCEICGKGFSQSSYLQIHQKAHSIEKPFKCEECGQGFNQSSRLQIHQL 579
Query: 1365 --------RCALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASEANLTGSQGL 1416
+C CG+ F R L+ H R H T +P N + +NL Q +
Sbjct: 580 IHTGEKPYKCEECGKGFSRRADLKIHCRIH--TGEKPYNCE-ECGKVFRQASNLLAHQRV 636
Query: 1417 ETQLGGAEPVPHLEDGVPRPGERSQSPIRAASSEAPEPLSWG--------AGKAGGWPVG 1468
+ G +P E G +S R+A +A + + G GK W +
Sbjct: 637 HS---GEKPFKCEECG--------KSFGRSAHLQAHQKVHTGDKPYKCDECGKGFKWSLN 685
Query: 1469 GGLGN--HSGGWVPQFLTRSEEPEDSVHRSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQ 1526
+ H+G P G+C + ++ +S QL
Sbjct: 686 LDMHQRVHTG------------------EKPYKCGEC----------GKYFSQASSLQLH 717
Query: 1527 PGSHS-----SCSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNH 1579
H+ C CGK + +S L +H T + C +C K F H H
Sbjct: 718 QSVHTGEKPYKCDVCGKVFSRSSQLQSHQRVHTGEKPYKCEICGKSFSWRSNLTVHHRIH 777
Query: 1580 IDAQTFACPDCGKAF-ESHQELAS 1602
+ +++ GK ES QE S
Sbjct: 778 VGDKSYKSNRGGKNIRESTQEKKS 801
Score = 115 bits (288), Expect = 4e-25
Identities = 118/495 (23%), Positives = 200/495 (40%), Gaps = 69/495 (13%)
Query: 821 HTCSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQ 879
+ C +CG +F A+ L H+ H ++C C K F L+SH + H T +
Sbjct: 363 YNCEECGRAFSQASHLQDHQRLHTGEKPFKCDACGKSFSRNSHLQSHQRVH-----TGEK 417
Query: 880 PFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAE 939
P+ C CG F + +H+R H+ + EE G + P+
Sbjct: 418 PYKCEECGKGFICSSNLYIHQR-VHTGE-----KPYKCEECGKGFSRPS----------- 460
Query: 940 LLNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDA 999
LQ + + + +IC CG+ + +L+ H + + + P G +
Sbjct: 461 ---SLQAH-QGVHTGEKSYICTVCGKGFTLSSNLQAHQRVHTG-----EKPYKCNECGKS 511
Query: 1000 MEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGK 1059
+ +V++ G E G S +Q + + +PF+C +CG+
Sbjct: 512 FRRNSHYQVHLVVHT----GEKPYKCEICGKGFSQSSYLQIHQKAHSIE-KPFKCEECGQ 566
Query: 1060 TYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEP----QVGP 1113
+ L H+ IH TG+ + C C + + A + H R H G +P + G
Sbjct: 567 GFNQSSRLQIHQLIH-TGEKPYKCEECGKGFSRRADLKIHCRIHT---GEKPYNCEECGK 622
Query: 1114 IPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKEEVWE 1173
+ A S+ L + G KP E G LQ KV ++ + E
Sbjct: 623 VFRQA-SNLLAHQRVHSG--EKPFKCEECGKSFGRSAHLQAHQKVHTGDKPYKCDE---- 675
Query: 1174 ETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FG 1231
KG + L+ ++ + E+P+ C CG+ + A SL H+ H TG +
Sbjct: 676 --CGKGFKWSLNLDMHQR----VHTGEKPYKCGECGKYFSQASSLQLHQSVH-TGEKPYK 728
Query: 1232 CQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHM------ERRG 1285
C C K FS L++H+R+H + ++C CGK+F R L H R+H+ RG
Sbjct: 729 CDVCGKVFSRSSQLQSHQRVHTGEKPYKCEICGKSFSWRSNLTVHHRIHVGDKSYKSNRG 788
Query: 1286 GGGTRKATREDRPFR 1300
G R++T+E + +
Sbjct: 789 GKNIRESTQEKKSIK 803
Score = 115 bits (287), Expect = 5e-25
Identities = 120/468 (25%), Positives = 182/468 (38%), Gaps = 86/468 (18%)
Query: 236 ERRYKCSQCGKTYKHAGSLTNHRQSHTLGIYPCAICFKEFSNLMALKNHSRLHAQYRPYH 295
E+ C + GK + ++ L H++ H C C KEFS L+ H ++H +PY
Sbjct: 277 EKSLTCVERGKGFCYSPVLPVHQKVHVGEKLKCDECGKEFSQGAHLQTHQKVHVIEKPYK 336
Query: 296 CPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSA 355
C C + F L H + H E+ EE G S L Q L+
Sbjct: 337 CKQCGKGFSRRSALNVHCKVHTAEKPY-NCEECGRAF-------SQASHLQDHQRLH--- 385
Query: 356 ELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFNA 413
+GE +PF+C CG+++ L +H++ H TG Y C C K +
Sbjct: 386 ----TGE---------KPFKCDACGKSFSRNSHLQSHQRVH-TGEKPYKCEECGKGFICS 431
Query: 414 AALKNHVRAH--HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTL----------- 460
+ L H R H +P + E G+ P+ L + H E+ T+
Sbjct: 432 SNLYIHQRVHTGEKPYK-CEECGKGFSRPSSLQAHQGVHTGEKSYICTVCGKGFTLSSNL 490
Query: 461 --------DHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNH 510
+PYKC+ECG+++R H H TGE Y+C +C + + L+ H
Sbjct: 491 QAHQRVHTGEKPYKCNECGKSFRRNSHYQVHLVVH-TGEKPYKCEICGKGFSQSSYLQIH 549
Query: 511 VRVHCKAARRSADIGAEGAPSHLKVELPPDPVEAEAAPHTDQDHVCKHEEEATDITPAAD 570
+ H + +G ++++ HT + K EE + AD
Sbjct: 550 QKAHSIEKPFKCEECGQGFNQSSRLQI-------HQLIHTGEKPY-KCEECGKGFSRRAD 601
Query: 571 -KTAAHI--------CSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRD 621
K I C CG +F A +L H H +GEK F C +
Sbjct: 602 LKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVH-SGEK-------------PFKCEE 647
Query: 622 CGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHS 667
CGKS+ S L H++ H TGD + C C K F + H R H+
Sbjct: 648 CGKSFGRSAHLQAHQKVH-TGDKPYKCDECGKGFKWSLNLDMHQRVHT 694
Score = 107 bits (268), Expect = 8e-23
Identities = 110/449 (24%), Positives = 179/449 (39%), Gaps = 81/449 (18%)
Query: 266 YPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQEPRW 325
Y C C K FS+L + H +L + + C + F L HQ+ H GE+ +
Sbjct: 252 YQCNECKKPFSDLSSFDLHQQLQSGEKSLTCVERGKGFCYSPVLPVHQKVHVGEKL--KC 309
Query: 326 EEKGMPTTNG---------HTDESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRC 376
+E G + G H E + + + L+ ++ + +P+ C
Sbjct: 310 DECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGFSRRSALNVHCKVHTA----EKPYNC 365
Query: 377 GDCGRTYRHAGSLINHRKSHQTGVYP--CSLCSKQLFNAAALKNHVRAH--HRPRQGVGE 432
+CGR + A L +H++ H TG P C C K + L++H R H +P + E
Sbjct: 366 EECGRAFSQASHLQDHQRLH-TGEKPFKCDACGKSFSRNSHLQSHQRVHTGEKPYK-CEE 423
Query: 433 NGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE- 491
G+ + + L + + H E +PYKC ECG+ + SL H+ H TGE
Sbjct: 424 CGKGFICSSNLYIHQRVHTGE---------KPYKCEECGKGFSRPSSLQAHQGVH-TGEK 473
Query: 492 -YQCSLCPRKYPNLMALRNHVRVHC-----------KAARRSADIGAEGAPSHLKVELPP 539
Y C++C + + L+ H RVH K+ RR++ HL V
Sbjct: 474 SYICTVCGKGFTLSSNLQAHQRVHTGEKPYKCNECGKSFRRNSHYQV-----HLVVHTGE 528
Query: 540 DPVEAE--AAPHTDQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTH 597
P + E + ++ H++ + P C CG F + L+ H L H
Sbjct: 529 KPYKCEICGKGFSQSSYLQIHQKAHSIEKPFK-------CEECGQGFNQSSRLQIHQLIH 581
Query: 598 GAGEKE------------------NSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTH 639
GEK + R T P + C +CGK +R + +L+ H++ H
Sbjct: 582 -TGEKPYKCEECGKGFSRRADLKIHCRIHTGEKP---YNCEECGKVFRQASNLLAHQRVH 637
Query: 640 Q-TGDFSCGACAKHFHTMAAMKNHLRRHS 667
F C C K F A ++ H + H+
Sbjct: 638 SGEKPFKCEECGKSFGRSAHLQAHQKVHT 666
Score = 67.4 bits (163), Expect = 1e-10
Identities = 118/611 (19%), Positives = 205/611 (33%), Gaps = 146/611 (23%)
Query: 619 CRDCGKSYRHSGSLINHRQTHQTGD-FSCGACAKHFHTMAAMKNHLRRHSRRRSRRHRKR 677
C +CGK + L H++ H + C C K F +A+ H + H+ K
Sbjct: 309 CDECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGFSRRSALNVHCKVHTA------EKP 362
Query: 678 AGGASGGREAKLLAAESWTRELEDNEGLESPQDPSGESPHGAEGNLESDGDCLQAESEGD 737
GR A S L+D++ L +GE P + D
Sbjct: 363 YNCEECGR------AFSQASHLQDHQRLH-----TGEKPF-----------------KCD 394
Query: 738 KCGLERDETHFQGDKESGGTGEGLERKDASLLDNLDIPGEEGGGTHFCDSLTGVDEDQKP 797
CG + TGE EE G C S + Q+
Sbjct: 395 ACGKSFSRNSHLQSHQRVHTGE------------KPYKCEECGKGFICSSNLYI--HQRV 440
Query: 798 ATGQPNSSSHSANAVTGWQAGAAHTCSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKE 856
TG+ + C +CG F + L +H+ H Y C++C K
Sbjct: 441 HTGE-----------------KPYKCEECGKGFSRPSSLQAHQGVHTGEKSYICTVCGKG 483
Query: 857 FDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEE 916
F L++H + H T +P+ C CG F RR +H + + E+
Sbjct: 484 FTLSSNLQAHQRVH-----TGEKPYKCNECGKSF---------RRNSHYQVHLVVHTGEK 529
Query: 917 GEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERH 976
+ + ++S LQ+ + + +++ + C CGQ ++ L+ H
Sbjct: 530 PYKCEICGKGFSQSSYLQIHQK--AHSIEKPFK----------CEECGQGFNQSSRLQIH 577
Query: 977 HQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSL 1036
+ + P G D + +++ G + E G +
Sbjct: 578 QLIHTG-----EKPYKCEECGKGFSRRADLKIHCRIHT----GEKPYNCEECGKVFRQAS 628
Query: 1037 CIQGGESLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAY 1094
+ + + + +PF+C +CGK++ L H+K+H TGD + C C + +
Sbjct: 629 NLLAHQRVHSGE-KPFKCEECGKSFGRSAHLQAHQKVH-TGDKPYKCDECGKGFKWSLNL 686
Query: 1095 RNHLRNHPRCKGSEPQVGPIPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQE 1154
H R H KP E G ++ LQ
Sbjct: 687 DMHQRVHT------------------------------GEKPYKCGECGKYFSQASSLQL 716
Query: 1155 ELKVEPLEEVARVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKH 1214
V E+ K +V + + +++ Q + E+P+ CE+CG+S+
Sbjct: 717 HQSVHTGEK--PYKCDVCGKVFSRSSQLQSH--------QRVHTGEKPYKCEICGKSFSW 766
Query: 1215 AGSLINHRQSH 1225
+L H + H
Sbjct: 767 RSNLTVHHRIH 777
>gi|74027274 zinc finger protein 226 isoform a [Homo sapiens]
Length = 803
Score = 171 bits (434), Expect = 5e-42
Identities = 148/585 (25%), Positives = 235/585 (40%), Gaps = 110/585 (18%)
Query: 1198 SSERPFSCEVCGRSYKHAGSLINHRQSHQTGHFGCQACSKGFSNLMSLKNHRRIHADPRR 1257
S E+ +C G+ + ++ L H++ H C C K FS L+ H+++H +
Sbjct: 275 SGEKSLTCVERGKGFCYSPVLPVHQKVHVGEKLKCDECGKEFSQGAHLQTHQKVHVIEKP 334
Query: 1258 FRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNH 1317
++C +CGK F R L H +VH ++P+ C +CGR + A L +H
Sbjct: 335 YKCKQCGKGFSRRSALNVHCKVHTA-------------EKPYNCEECGRAFSQASHLQDH 381
Query: 1318 RRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPG 1375
+R H TG+ + C C K++S L+ HQR+H+ + +C CG+ F
Sbjct: 382 QRLH-TGEKPFKCDACGKSFSRNSHLQSHQRVHTGEK----------PYKCEECGKGFIC 430
Query: 1376 RGSLERHLREH--EETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGV 1433
+L H R H E+ + G+G + ++L QG+ T
Sbjct: 431 SSNLYIHQRVHTGEKPYKCEECGKG-----FSRPSSLQAHQGVHT--------------- 470
Query: 1434 PRPGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSV 1493
GE+S + GK G+ + L H + + E S
Sbjct: 471 ---GEKSY-------------ICTVCGK--GFTLSSNLQAHQRVHTGEKPYKCNECGKSF 512
Query: 1494 HRSP-------CHAGD----CQLNGPTLSHMDSWDNRDNSSQLQPGSHS-----SCSQCG 1537
R+ H G+ C++ G S + + Q+ +HS C +CG
Sbjct: 513 RRNSHYQVHLVVHTGEKPYKCEICGKGFS-------QSSYLQIHQKAHSIEKPFKCEECG 565
Query: 1538 KTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFE 1595
+ + QS L H T + C C K F K H H + + C +CGK F
Sbjct: 566 QGFNQSSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFR 625
Query: 1596 SHQELASHLQAHARGHS-QVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGE 1654
AS+L AH R HS + P + EE + Q T P +
Sbjct: 626 Q----ASNLLAHQRVHSGEKPFKCEECGKSFGRSAHLQA---------HQKVHTGDKPYK 672
Query: 1655 SVERARGGQAVTSMAAEDK----ERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLC 1709
E +G + ++ + E+P++C +CG+ + A SL HQ HT Y C +C
Sbjct: 673 CDECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKYFSQASSLQLHQSVHTGEKPYKCDVC 732
Query: 1710 PKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVH 1754
K+ L++H R HT K + C ICGK+F + L H R+H
Sbjct: 733 GKVFSRSSQLQSHQRVHTGEKPYKCEICGKSFSWRSNLTVHHRIH 777
Score = 169 bits (429), Expect = 2e-41
Identities = 157/602 (26%), Positives = 240/602 (39%), Gaps = 102/602 (16%)
Query: 1220 NHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQ 1277
+H TG + C C K FS+L S H+++ + + C E GK F L HQ
Sbjct: 240 DHNSMIHTGQKSYQCNECKKPFSDLSSFDLHQQLQSGEKSLTCVERGKGFCYSPVLPVHQ 299
Query: 1278 RVHM---------ERRGGGGTRKATRE-----DRPFRCGQCGRTYRHAGSLLNHRRSHET 1323
+VH+ + G T + ++P++C QCG+ + +L H + H
Sbjct: 300 KVHVGEKLKCDECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGFSRRSALNVHCKVHTA 359
Query: 1324 GQ-YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERH 1382
+ Y+C C + +S L+DHQRLH+ + +C CG+SF L+ H
Sbjct: 360 EKPYNCEECGRAFSQASHLQDHQRLHTGEK----------PFKCDACGKSFSRNSHLQSH 409
Query: 1383 LREHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRPGERSQS 1442
R H T +P + G S +NL Q + T G +P E G G S
Sbjct: 410 QRVH--TGEKPYKCEECGKGFICS-SNLYIHQRVHT---GEKPYKCEECG---KGFSRPS 460
Query: 1443 PIRAASSEAPEPLSWGAGKAG-GWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSP---- 1497
++A S+ G G+ + L H + + E S R+
Sbjct: 461 SLQAHQGVHTGEKSYICTVCGKGFTLSSNLQAHQRVHTGEKPYKCNECGKSFRRNSHYQV 520
Query: 1498 ---CHAGD----CQLNGPTLSHMDSWDNRDNSSQLQPGSHS-----SCSQCGKTYCQSGS 1545
H G+ C++ G S + + Q+ +HS C +CG+ + QS
Sbjct: 521 HLVVHTGEKPYKCEICGKGFS-------QSSYLQIHQKAHSIEKPFKCEECGQGFNQSSR 573
Query: 1546 LLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASH 1603
L H T + C C K F K H H + + C +CGK F AS+
Sbjct: 574 LQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQ----ASN 629
Query: 1604 LQAHARGHS-QVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVERARGG 1662
L AH R HS + P + EE G+S R+
Sbjct: 630 LLAHQRVHSGEKPFKCEEC-------------------------------GKSFGRSAHL 658
Query: 1663 QAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLCPKLLPNLLSLKN 1721
QA + DK P++C +CG+ ++ + +L HQ+ HT Y C C K SL+
Sbjct: 659 QAHQKVHTGDK--PYKCDECGKGFKWSLNLDMHQRVHTGEKPYKCGECGKYFSQASSLQL 716
Query: 1722 HSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQ 1781
H HT K + C +CGK F +++L+ H RVH E P+ C C + F R + H +
Sbjct: 717 HQSVHTGEKPYKCDVCGKVFSRSSQLQSHQRVHT-GEKPYKCEICGKSFSWRSNLTVHHR 775
Query: 1782 QH 1783
H
Sbjct: 776 IH 777
Score = 159 bits (402), Expect = 2e-38
Identities = 152/584 (26%), Positives = 240/584 (41%), Gaps = 82/584 (14%)
Query: 822 TCSDCGHSFPHATGLLSHRPCHPPGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPF 881
TC + G F ++ L H+ H +C C KEF L++H + H +P+
Sbjct: 281 TCVERGKGFCYSPVLPVHQKVHVGEKLKCDECGKEFSQGAHLQTHQKVH-----VIEKPY 335
Query: 882 LCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELL 941
C CG F R+ +H + H T EE G A S+A L
Sbjct: 336 KCKQCGKGFSRRSALNVHCK-VH-----TAEKPYNCEECGRA-----------FSQASHL 378
Query: 942 NQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAME 1001
QR L + C CG+++ S H QS T +K P G
Sbjct: 379 QDHQR----LHTGEKPFKCDACGKSF----SRNSHLQSHQRVHTGEK-PYKCEECGKGFI 429
Query: 1002 MVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTY 1061
+ + V+ +GE + G G SL G + + + C CGK +
Sbjct: 430 CSSNLYIHQRVH--TGEKPYKCEECGKGFSRPSSLQAHQG---VHTGEKSYICTVCGKGF 484
Query: 1062 RHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPI--PEA 1117
+L H+++H TG+ + C C + + + Y+ HL H G +P I
Sbjct: 485 TLSSNLQAHQRVH-TGEKPYKCNECGKSFRRNSHYQVHLVVH---TGEKPYKCEICGKGF 540
Query: 1118 AGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKEEVWEETTV 1177
+ SS LQ+ KP E G G + +LQ + E+ + +E +
Sbjct: 541 SQSSYLQIHQ-KAHSIEKPFKCEECGQGFNQSSRLQIHQLIHTGEKPYKCEECGKGFSRR 599
Query: 1178 KGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQ-TGHFGCQACS 1236
+I R+ T EK P++CE CG+ ++ A +L+ H++ H F C+ C
Sbjct: 600 ADLKIHCRIHTGEK----------PYNCEECGKVFRQASNLLAHQRVHSGEKPFKCEECG 649
Query: 1237 KGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATRED 1296
K F L+ H+++H + ++C ECGK F+ L HQRVH +
Sbjct: 650 KSFGRSAHLQAHQKVHTGDKPYKCDECGKGFKWSLNLDMHQRVH-------------TGE 696
Query: 1297 RPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRR 1354
+P++CG+CG+ + A SL H+ H TG+ Y C C K +S L+ HQR+H+ +
Sbjct: 697 KPYKCGECGKYFSQASSLQLHQSVH-TGEKPYKCDVCGKVFSRSSQLQSHQRVHTGEK-- 753
Query: 1355 RAGRSRRTAVRCALCGRSFPGRGSLERHLREHEETEREPANGQG 1398
+C +CG+SF R +L H R H + +N G
Sbjct: 754 --------PYKCEICGKSFSWRSNLTVHHRIHVGDKSYKSNRGG 789
Score = 140 bits (354), Expect = 9e-33
Identities = 125/468 (26%), Positives = 192/468 (41%), Gaps = 61/468 (13%)
Query: 236 ERRYKCSQCGKTYKHAGSLTNHRQSHTLGIYP--CAICFKEFSNLMALKNHSRLHAQYRP 293
E+ Y C +CG+ + A L +H++ HT G P C C K FS L++H R+H +P
Sbjct: 360 EKPYNCEECGRAFSQASHLQDHQRLHT-GEKPFKCDACGKSFSRNSHLQSHQRVHTGEKP 418
Query: 294 YHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGM-----PTTNGHTDESSQDQLPSA 348
Y C C + F L HQ+ H GE+ + EE G + H + ++
Sbjct: 419 YKCEECGKGFICSSNLYIHQRVHTGEKPY-KCEECGKGFSRPSSLQAHQGVHTGEKSYIC 477
Query: 349 QMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTGV--YPCSLC 406
+ LS++ + +P++C +CG+++R H H TG Y C +C
Sbjct: 478 TVCGKGFTLSSNLQAHQRVHTGEKPYKCNECGKSFRRNSHYQVHLVVH-TGEKPYKCEIC 536
Query: 407 SKQLFNAAALKNHVRAHHRPRQGVGEN-GQPSVPPAPLLLAETTHKEEEDPTTTLDHRPY 465
K ++ L+ H +AH + E GQ + L + + H E +PY
Sbjct: 537 GKGFSQSSYLQIHQKAHSIEKPFKCEECGQGFNQSSRLQIHQLIHTGE---------KPY 587
Query: 466 KCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVH-------CK 516
KC ECG+ + R L H H TGE Y C C + + L H RVH C+
Sbjct: 588 KCEECGKGFSRRADLKIHCRIH-TGEKPYNCEECGKVFRQASNLLAHQRVHSGEKPFKCE 646
Query: 517 AARRSADIGAEGAPSHLKVELPPDPVEAEAAPHTDQD--HVCKHEEEATDITPAADKTAA 574
+S A +H KV P + + + ++ H+ T P
Sbjct: 647 ECGKSFGRSAH-LQAHQKVHTGDKPYKCDECGKGFKWSLNLDMHQRVHTGEKP------- 698
Query: 575 HICSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLIN 634
+ C CG F A SL+ H H GEK + C CGK + S L +
Sbjct: 699 YKCGECGKYFSQASSLQLHQSVH-TGEKP-------------YKCDVCGKVFSRSSQLQS 744
Query: 635 HRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHSRRRSRRHRKRAGG 680
H++ H TG+ + C C K F + + H R H +S ++ GG
Sbjct: 745 HQRVH-TGEKPYKCEICGKSFSWRSNLTVHHRIHVGDKS--YKSNRGG 789
Score = 139 bits (351), Expect = 2e-32
Identities = 142/568 (25%), Positives = 223/568 (39%), Gaps = 102/568 (17%)
Query: 1242 LMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRC 1301
+++ ++ IH + ++C+EC K F HQ++ G + T C
Sbjct: 236 ILTFDHNSMIHTGQKSYQCNECKKPFSDLSSFDLHQQLQ------SGEKSLT-------C 282
Query: 1302 GQCGRTYRHAGSLLNHRRSHETGQYSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRR 1361
+ G+ + ++ L H++ H + C C K +S L+ HQ++H +
Sbjct: 283 VERGKGFCYSPVLPVHQKVHVGEKLKCDECGKEFSQGAHLQTHQKVHVIEK--------- 333
Query: 1362 TAVRCALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASEAN-LTGSQGLETQL 1420
+C CG+ F R +L H + H T +P N + G A S+A+ L Q L T
Sbjct: 334 -PYKCKQCGKGFSRRSALNVHCKVH--TAEKPYNCEEC--GRAFSQASHLQDHQRLHT-- 386
Query: 1421 GGAEPVPHLEDGVPRPGERS---QSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGG 1477
G +P D + R+ QS R + E P G G S
Sbjct: 387 -GEKPFKC--DACGKSFSRNSHLQSHQRVHTGEKPYKCE---------ECGKGFICSSNL 434
Query: 1478 WVPQFLTRSEEPEDSVHRSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHSS----- 1532
++ Q + E+P C+ G S R +S Q G H+
Sbjct: 435 YIHQRVHTGEKPYK-----------CEECGKGFS-------RPSSLQAHQGVHTGEKSYI 476
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C+ CGK + S +L H T + C C K F + H H + + C C
Sbjct: 477 CTVCGKGFTLSSNLQAHQRVHTGEKPYKCNECGKSFRRNSHYQVHLVVHTGEKPYKCEIC 536
Query: 1591 GKAFESHQELASHLQAHARGHS-QVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSE-- 1647
GK F +S+LQ H + HS + P + EE GQG Q + +
Sbjct: 537 GKGFSQ----SSYLQIHQKAHSIEKPFKCEEC---------------GQGFNQSSRLQIH 577
Query: 1648 ----TPRGPGESVERARGGQAVTSMAAEDK----ERPFRCTQCGRSYRHAGSLLNHQKAH 1699
T P + E +G + + E+P+ C +CG+ +R A +LL HQ+ H
Sbjct: 578 QLIHTGEKPYKCEECGKGFSRRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVH 637
Query: 1700 TTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPRE 1758
+ + C C K L+ H + HT K + C CGK F+ + L+ H RVH E
Sbjct: 638 SGEKPFKCEECGKSFGRSAHLQAHQKVHTGDKPYKCDECGKGFKWSLNLDMHQRVHTG-E 696
Query: 1759 GPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
P+ C C ++F + S HQ H E
Sbjct: 697 KPYKCGECGKYFSQASSLQLHQSVHTGE 724
Score = 134 bits (338), Expect = 6e-31
Identities = 135/538 (25%), Positives = 210/538 (39%), Gaps = 98/538 (18%)
Query: 8 LSCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHR 67
L C +C + F L H+++ I +PY+C+QCG+G+ +L H
Sbjct: 307 LKCDECGKEFSQGAHLQTHQKV------------HVIEKPYKCKQCGKGFSRRSALNVHC 354
Query: 68 RTHETGL-FPCTTCGKDFSNPMALKSHMRTHAPE------------GRRRHRPPRPKEAT 114
+ H + C CG+ FS L+ H R H E R H +
Sbjct: 355 KVHTAEKPYNCEECGRAFSQASHLQDHQRLHTGEKPFKCDACGKSFSRNSHLQSHQR--- 411
Query: 115 PHLQGETVSTDSWGQR-LGSSEGWENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQRE 172
H + + G+ + SS + +Q HT E P CE G P+
Sbjct: 412 VHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKPYKCEE-------CGKGFSRPS---- 460
Query: 173 GLASHPGPEDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPP 232
L +H G G + + +L SNL+ + TG
Sbjct: 461 SLQAHQGVHTGEKSYICTVCG--------KGFTLSSNLQAHQRV----HTG--------- 499
Query: 233 AEEERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQY 291
E+ YKC++CGK+++ H HT Y C IC K FS L+ H + H+
Sbjct: 500 ---EKPYKCNECGKSFRRNSHYQVHLVVHTGEKPYKCEICGKGFSQSSYLQIHQKAHSIE 556
Query: 292 RPYHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNG---------HTDESSQ 342
+P+ C C + F L HQ H GE+ + EE G + HT E
Sbjct: 557 KPFKCEECGQGFNQSSRLQIHQLIHTGEKPY-KCEECGKGFSRRADLKIHCRIHTGEKPY 615
Query: 343 DQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--V 400
+ ++ ++ L + +PF+C +CG+++ + L H+K H TG
Sbjct: 616 NCEECGKVFRQASNLLAHQRVHSG----EKPFKCEECGKSFGRSAHLQAHQKVH-TGDKP 670
Query: 401 YPCSLCSKQLFNAAALKNHVRAH--HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTT 458
Y C C K + L H R H +P + GE G+ + L L ++ H E
Sbjct: 671 YKCDECGKGFKWSLNLDMHQRVHTGEKPYK-CGECGKYFSQASSLQLHQSVHTGE----- 724
Query: 459 TLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVH 514
+PYKC CG+ + L +H+ H TGE Y+C +C + + L H R+H
Sbjct: 725 ----KPYKCDVCGKVFSRSSQLQSHQRVH-TGEKPYKCEICGKSFSWRSNLTVHHRIH 777
Score = 130 bits (327), Expect = 1e-29
Identities = 150/657 (22%), Positives = 238/657 (36%), Gaps = 143/657 (21%)
Query: 7 SLSCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNH 66
S C++C++ F L H++L Q E++ C + G+G+ + L H
Sbjct: 251 SYQCNECKKPFSDLSSFDLHQQL------QSGEKS------LTCVERGKGFCYSPVLPVH 298
Query: 67 RRTHETGLFPCTTCGKDFSNPMALKSHMRTHAPEGRRR---------HRPPRPKEATPHL 117
++ H C CGK+FS L++H + H E + R H
Sbjct: 299 QKVHVGEKLKCDECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGFSRRSALNVHCKVHT 358
Query: 118 QGETVSTDSWGQRLG-SSEGWENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQREGLA 175
+ + + G+ +S ++Q HT E P C++ + + L + QR
Sbjct: 359 AEKPYNCEECGRAFSQASHLQDHQRLHTGEKPFKCDACGKSFSRN---SHLQSHQRVHTG 415
Query: 176 SHPGP-EDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAE 234
P E+ G+ S+N Y+ + V TG
Sbjct: 416 EKPYKCEECGKGFICSSN-------------------LYIHQRV--HTG----------- 443
Query: 235 EERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRP 293
E+ YKC +CGK + SL H+ HT Y C +C K F+ L+ H R+H +P
Sbjct: 444 -EKPYKCEECGKGFSRPSSLQAHQGVHTGEKSYICTVCGKGFTLSSNLQAHQRVHTGEKP 502
Query: 294 YHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNG 353
Y C C + FR H H GE+ ++
Sbjct: 503 YKCNECGKSFRRNSHYQVHLVVHTGEKPY------------------------KCEICGK 538
Query: 354 SAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLF 411
S+ ++ +PF+C +CG+ + + L H+ H TG Y C C K
Sbjct: 539 GFSQSSYLQIHQKAHSIEKPFKCEECGQGFNQSSRLQIHQLIH-TGEKPYKCEECGKGFS 597
Query: 412 NAAALKNHVRAHHRPR-QGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSEC 470
A LK H R H + E G+ + LL + H E +P+KC EC
Sbjct: 598 RRADLKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVHSGE---------KPFKCEEC 648
Query: 471 GRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHCKAARRSADIGAEG 528
G+++ L H+ H TG+ Y+C C + + + L H RVH + G G
Sbjct: 649 GKSFGRSAHLQAHQKVH-TGDKPYKCDECGKGFKWSLNLDMHQRVH--TGEKPYKCGECG 705
Query: 529 APSHLKVELPPDPVEAEAAPHTDQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAE 588
K ++ + HT + + C +CG +F +
Sbjct: 706 -----KYFSQASSLQLHQSVHTGE--------------------KPYKCDVCGKVFSRSS 740
Query: 589 SLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGDFS 645
L+ H H GEK + C CGKS+ +L H + H GD S
Sbjct: 741 QLQSHQRVH-TGEK-------------PYKCEICGKSFSWRSNLTVHHRIH-VGDKS 782
Score = 119 bits (299), Expect = 2e-26
Identities = 144/624 (23%), Positives = 236/624 (37%), Gaps = 129/624 (20%)
Query: 1043 SLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGDFLCPVCSR----CY-PNLAAYRN- 1096
S++ + ++CN+C K + S H+++ Q+G+ R CY P L ++
Sbjct: 243 SMIHTGQKSYQCNECKKPFSDLSSFDLHQQL-QSGEKSLTCVERGKGFCYSPVLPVHQKV 301
Query: 1097 HLRNHPRCKGSEPQVGPIPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEEL 1156
H+ +C + ++ V KP + G G + L
Sbjct: 302 HVGEKLKCDECGKEFSQGAHLQTHQKVHV-------IEKPYKCKQCGKGFSRRSALNVHC 354
Query: 1157 KVEPLEEVARVKEEVWEETTVKGEEIEPRLETAEKGCQTEA------------------S 1198
KV E+ +E + + RL T EK + +A +
Sbjct: 355 KVHTAEKPYNCEECGRAFSQASHLQDHQRLHTGEKPFKCDACGKSFSRNSHLQSHQRVHT 414
Query: 1199 SERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPR 1256
E+P+ CE CG+ + + +L H++ H TG + C+ C KGFS SL+ H+ +H +
Sbjct: 415 GEKPYKCEECGKGFICSSNLYIHQRVH-TGEKPYKCEECGKGFSRPSSLQAHQGVHTGEK 473
Query: 1257 RFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLN 1316
+ C+ CGK F L L +HQRVH ++P++C +CG+++R
Sbjct: 474 SYICTVCGKGFTLSSNLQAHQRVH-------------TGEKPYKCNECGKSFRRNSHYQV 520
Query: 1317 HRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHS-------ENRRRRAGRSRRTAV--- 1364
H H TG+ Y C C K +S L+ HQ+ HS E + +S R +
Sbjct: 521 HLVVH-TGEKPYKCEICGKGFSQSSYLQIHQKAHSIEKPFKCEECGQGFNQSSRLQIHQL 579
Query: 1365 --------RCALCGRSFPGRGSLERHLREHEETEREPANGQGGLDGTAASEANLTGSQGL 1416
+C CG+ F R L+ H R H T +P N + +NL Q +
Sbjct: 580 IHTGEKPYKCEECGKGFSRRADLKIHCRIH--TGEKPYNCE-ECGKVFRQASNLLAHQRV 636
Query: 1417 ETQLGGAEPVPHLEDGVPRPGERSQSPIRAASSEAPEPLSWG--------AGKAGGWPVG 1468
+ G +P E G +S R+A +A + + G GK W +
Sbjct: 637 HS---GEKPFKCEECG--------KSFGRSAHLQAHQKVHTGDKPYKCDECGKGFKWSLN 685
Query: 1469 GGLGN--HSGGWVPQFLTRSEEPEDSVHRSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQ 1526
+ H+G P G+C + ++ +S QL
Sbjct: 686 LDMHQRVHTG------------------EKPYKCGEC----------GKYFSQASSLQLH 717
Query: 1527 PGSHS-----SCSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNH 1579
H+ C CGK + +S L +H T + C +C K F H H
Sbjct: 718 QSVHTGEKPYKCDVCGKVFSRSSQLQSHQRVHTGEKPYKCEICGKSFSWRSNLTVHHRIH 777
Query: 1580 IDAQTFACPDCGKAF-ESHQELAS 1602
+ +++ GK ES QE S
Sbjct: 778 VGDKSYKSNRGGKNIRESTQEKKS 801
Score = 115 bits (288), Expect = 4e-25
Identities = 118/495 (23%), Positives = 200/495 (40%), Gaps = 69/495 (13%)
Query: 821 HTCSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQ 879
+ C +CG +F A+ L H+ H ++C C K F L+SH + H T +
Sbjct: 363 YNCEECGRAFSQASHLQDHQRLHTGEKPFKCDACGKSFSRNSHLQSHQRVH-----TGEK 417
Query: 880 PFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAE 939
P+ C CG F + +H+R H+ + EE G + P+
Sbjct: 418 PYKCEECGKGFICSSNLYIHQR-VHTGE-----KPYKCEECGKGFSRPS----------- 460
Query: 940 LLNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDA 999
LQ + + + +IC CG+ + +L+ H + + + P G +
Sbjct: 461 ---SLQAH-QGVHTGEKSYICTVCGKGFTLSSNLQAHQRVHTG-----EKPYKCNECGKS 511
Query: 1000 MEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGK 1059
+ +V++ G E G S +Q + + +PF+C +CG+
Sbjct: 512 FRRNSHYQVHLVVHT----GEKPYKCEICGKGFSQSSYLQIHQKAHSIE-KPFKCEECGQ 566
Query: 1060 TYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEP----QVGP 1113
+ L H+ IH TG+ + C C + + A + H R H G +P + G
Sbjct: 567 GFNQSSRLQIHQLIH-TGEKPYKCEECGKGFSRRADLKIHCRIHT---GEKPYNCEECGK 622
Query: 1114 IPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKEEVWE 1173
+ A S+ L + G KP E G LQ KV ++ + E
Sbjct: 623 VFRQA-SNLLAHQRVHSG--EKPFKCEECGKSFGRSAHLQAHQKVHTGDKPYKCDE---- 675
Query: 1174 ETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FG 1231
KG + L+ ++ + E+P+ C CG+ + A SL H+ H TG +
Sbjct: 676 --CGKGFKWSLNLDMHQR----VHTGEKPYKCGECGKYFSQASSLQLHQSVH-TGEKPYK 728
Query: 1232 CQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHM------ERRG 1285
C C K FS L++H+R+H + ++C CGK+F R L H R+H+ RG
Sbjct: 729 CDVCGKVFSRSSQLQSHQRVHTGEKPYKCEICGKSFSWRSNLTVHHRIHVGDKSYKSNRG 788
Query: 1286 GGGTRKATREDRPFR 1300
G R++T+E + +
Sbjct: 789 GKNIRESTQEKKSIK 803
Score = 115 bits (287), Expect = 5e-25
Identities = 120/468 (25%), Positives = 182/468 (38%), Gaps = 86/468 (18%)
Query: 236 ERRYKCSQCGKTYKHAGSLTNHRQSHTLGIYPCAICFKEFSNLMALKNHSRLHAQYRPYH 295
E+ C + GK + ++ L H++ H C C KEFS L+ H ++H +PY
Sbjct: 277 EKSLTCVERGKGFCYSPVLPVHQKVHVGEKLKCDECGKEFSQGAHLQTHQKVHVIEKPYK 336
Query: 296 CPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSA 355
C C + F L H + H E+ EE G S L Q L+
Sbjct: 337 CKQCGKGFSRRSALNVHCKVHTAEKPY-NCEECGRAF-------SQASHLQDHQRLH--- 385
Query: 356 ELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFNA 413
+GE +PF+C CG+++ L +H++ H TG Y C C K +
Sbjct: 386 ----TGE---------KPFKCDACGKSFSRNSHLQSHQRVH-TGEKPYKCEECGKGFICS 431
Query: 414 AALKNHVRAH--HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTL----------- 460
+ L H R H +P + E G+ P+ L + H E+ T+
Sbjct: 432 SNLYIHQRVHTGEKPYK-CEECGKGFSRPSSLQAHQGVHTGEKSYICTVCGKGFTLSSNL 490
Query: 461 --------DHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNH 510
+PYKC+ECG+++R H H TGE Y+C +C + + L+ H
Sbjct: 491 QAHQRVHTGEKPYKCNECGKSFRRNSHYQVHLVVH-TGEKPYKCEICGKGFSQSSYLQIH 549
Query: 511 VRVHCKAARRSADIGAEGAPSHLKVELPPDPVEAEAAPHTDQDHVCKHEEEATDITPAAD 570
+ H + +G ++++ HT + K EE + AD
Sbjct: 550 QKAHSIEKPFKCEECGQGFNQSSRLQI-------HQLIHTGEKPY-KCEECGKGFSRRAD 601
Query: 571 -KTAAHI--------CSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRD 621
K I C CG +F A +L H H +GEK F C +
Sbjct: 602 LKIHCRIHTGEKPYNCEECGKVFRQASNLLAHQRVH-SGEK-------------PFKCEE 647
Query: 622 CGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHS 667
CGKS+ S L H++ H TGD + C C K F + H R H+
Sbjct: 648 CGKSFGRSAHLQAHQKVH-TGDKPYKCDECGKGFKWSLNLDMHQRVHT 694
Score = 107 bits (268), Expect = 8e-23
Identities = 110/449 (24%), Positives = 179/449 (39%), Gaps = 81/449 (18%)
Query: 266 YPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQEPRW 325
Y C C K FS+L + H +L + + C + F L HQ+ H GE+ +
Sbjct: 252 YQCNECKKPFSDLSSFDLHQQLQSGEKSLTCVERGKGFCYSPVLPVHQKVHVGEKL--KC 309
Query: 326 EEKGMPTTNG---------HTDESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRC 376
+E G + G H E + + + L+ ++ + +P+ C
Sbjct: 310 DECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGFSRRSALNVHCKVHTA----EKPYNC 365
Query: 377 GDCGRTYRHAGSLINHRKSHQTGVYP--CSLCSKQLFNAAALKNHVRAH--HRPRQGVGE 432
+CGR + A L +H++ H TG P C C K + L++H R H +P + E
Sbjct: 366 EECGRAFSQASHLQDHQRLH-TGEKPFKCDACGKSFSRNSHLQSHQRVHTGEKPYK-CEE 423
Query: 433 NGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE- 491
G+ + + L + + H E +PYKC ECG+ + SL H+ H TGE
Sbjct: 424 CGKGFICSSNLYIHQRVHTGE---------KPYKCEECGKGFSRPSSLQAHQGVH-TGEK 473
Query: 492 -YQCSLCPRKYPNLMALRNHVRVHC-----------KAARRSADIGAEGAPSHLKVELPP 539
Y C++C + + L+ H RVH K+ RR++ HL V
Sbjct: 474 SYICTVCGKGFTLSSNLQAHQRVHTGEKPYKCNECGKSFRRNSHYQV-----HLVVHTGE 528
Query: 540 DPVEAE--AAPHTDQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTH 597
P + E + ++ H++ + P C CG F + L+ H L H
Sbjct: 529 KPYKCEICGKGFSQSSYLQIHQKAHSIEKPFK-------CEECGQGFNQSSRLQIHQLIH 581
Query: 598 GAGEKE------------------NSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTH 639
GEK + R T P + C +CGK +R + +L+ H++ H
Sbjct: 582 -TGEKPYKCEECGKGFSRRADLKIHCRIHTGEKP---YNCEECGKVFRQASNLLAHQRVH 637
Query: 640 Q-TGDFSCGACAKHFHTMAAMKNHLRRHS 667
F C C K F A ++ H + H+
Sbjct: 638 SGEKPFKCEECGKSFGRSAHLQAHQKVHT 666
Score = 67.4 bits (163), Expect = 1e-10
Identities = 118/611 (19%), Positives = 205/611 (33%), Gaps = 146/611 (23%)
Query: 619 CRDCGKSYRHSGSLINHRQTHQTGD-FSCGACAKHFHTMAAMKNHLRRHSRRRSRRHRKR 677
C +CGK + L H++ H + C C K F +A+ H + H+ K
Sbjct: 309 CDECGKEFSQGAHLQTHQKVHVIEKPYKCKQCGKGFSRRSALNVHCKVHTA------EKP 362
Query: 678 AGGASGGREAKLLAAESWTRELEDNEGLESPQDPSGESPHGAEGNLESDGDCLQAESEGD 737
GR A S L+D++ L +GE P + D
Sbjct: 363 YNCEECGR------AFSQASHLQDHQRLH-----TGEKPF-----------------KCD 394
Query: 738 KCGLERDETHFQGDKESGGTGEGLERKDASLLDNLDIPGEEGGGTHFCDSLTGVDEDQKP 797
CG + TGE EE G C S + Q+
Sbjct: 395 ACGKSFSRNSHLQSHQRVHTGE------------KPYKCEECGKGFICSSNLYI--HQRV 440
Query: 798 ATGQPNSSSHSANAVTGWQAGAAHTCSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKE 856
TG+ + C +CG F + L +H+ H Y C++C K
Sbjct: 441 HTGE-----------------KPYKCEECGKGFSRPSSLQAHQGVHTGEKSYICTVCGKG 483
Query: 857 FDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEE 916
F L++H + H T +P+ C CG F RR +H + + E+
Sbjct: 484 FTLSSNLQAHQRVH-----TGEKPYKCNECGKSF---------RRNSHYQVHLVVHTGEK 529
Query: 917 GEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERH 976
+ + ++S LQ+ + + +++ + C CGQ ++ L+ H
Sbjct: 530 PYKCEICGKGFSQSSYLQIHQK--AHSIEKPFK----------CEECGQGFNQSSRLQIH 577
Query: 977 HQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSL 1036
+ + P G D + +++ G + E G +
Sbjct: 578 QLIHTG-----EKPYKCEECGKGFSRRADLKIHCRIHT----GEKPYNCEECGKVFRQAS 628
Query: 1037 CIQGGESLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAY 1094
+ + + + +PF+C +CGK++ L H+K+H TGD + C C + +
Sbjct: 629 NLLAHQRVHSGE-KPFKCEECGKSFGRSAHLQAHQKVH-TGDKPYKCDECGKGFKWSLNL 686
Query: 1095 RNHLRNHPRCKGSEPQVGPIPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQE 1154
H R H KP E G ++ LQ
Sbjct: 687 DMHQRVHT------------------------------GEKPYKCGECGKYFSQASSLQL 716
Query: 1155 ELKVEPLEEVARVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKH 1214
V E+ K +V + + +++ Q + E+P+ CE+CG+S+
Sbjct: 717 HQSVHTGEK--PYKCDVCGKVFSRSSQLQSH--------QRVHTGEKPYKCEICGKSFSW 766
Query: 1215 AGSLINHRQSH 1225
+L H + H
Sbjct: 767 RSNLTVHHRIH 777
>gi|209954795 zinc finger protein 761 [Homo sapiens]
Length = 746
Score = 164 bits (414), Expect = 1e-39
Identities = 148/570 (25%), Positives = 223/570 (39%), Gaps = 107/570 (18%)
Query: 1198 SSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADP 1255
+ E P+ C CG+++ SL HR+ H TG + C+ C K F L+ HR IH +
Sbjct: 265 TGENPYKCNECGKTFSQTSSLTCHRRLH-TGEKPYKCEECDKAFHFKSILERHRIIHTEE 323
Query: 1256 RRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLL 1315
+ ++C+ECGK FR + L H R+H ++P++C +CG+T+ H SL
Sbjct: 324 KPYKCNECGKTFRQKSILTRHHRLH-------------TGEKPYKCNECGKTFSHKSSLT 370
Query: 1316 NHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSF 1373
H R H TG+ Y C C KT+S++ +L H+RLH+ + +C C +++
Sbjct: 371 CHHRLH-TGEKPYKCNECGKTFSHKSSLTCHRRLHTGEK----------PYKCEECDKAY 419
Query: 1374 PGRGSLERHLREHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLE-DG 1432
R + E H + H E N G T + ++LT + T G +P E D
Sbjct: 420 SFRSNFEIHRKIHTEDNAYKCNECG---KTFSRTSSLTCHRRRHT---GEQPYKCEECDK 473
Query: 1433 VPRPGERSQSPIRAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDS 1492
R + R + E P + GK T S + +
Sbjct: 474 AFRFKSNLERHRRIHTGEKPYKCN-ECGK----------------------TFSRKSYLT 510
Query: 1493 VHRSPCHAGD----CQLNGPTLSHMDSWD-NRDNSSQLQPGSHSSCSQCGKTYCQSGSLL 1547
H H G+ C G T S S +R S +P C GKT+ Q +L
Sbjct: 511 CHHR-LHTGEKAYKCNECGKTFSWKSSLTCHRRLHSGEKPYKCKEC---GKTFNQQLTLK 566
Query: 1548 NHNT--NKTDRHYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQ 1605
H + + + C K + + H H + + C +CGK F L H +
Sbjct: 567 RHRRLHSGENPYKCEDSDKAYSFKSNLEIHQKIHTEENPYKCNECGKTFSRTSSLTCHRR 626
Query: 1606 AHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVERARGGQAV 1665
H TGE KA S E R G
Sbjct: 627 LH--------------------TGEKPYKCEECDKAFRVKSNL-----EGHRRIHTG--- 658
Query: 1666 TSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLCPKLLPNLLSLKNHSR 1724
E+P++C +CG+++ + H + HT Y C+ C K SL H R
Sbjct: 659 --------EKPYKCNECGKTFSRKSYFICHHRLHTGEKPYKCNECGKNFSQKSSLICHHR 710
Query: 1725 THTDPKRHCCSICGKAFRTAARLEGHGRVH 1754
HT K + C+ CGK F + L H R+H
Sbjct: 711 LHTGEKPYKCNECGKTFSQKSNLTCHRRLH 740
Score = 159 bits (402), Expect = 2e-38
Identities = 142/586 (24%), Positives = 232/586 (39%), Gaps = 71/586 (12%)
Query: 1209 GRSYKHAGSLINHRQSH-QTGHFGCQACSKGFSNLMSLKNHRRIH-ADPRRFRCSECGKA 1266
G ++ ++ L ++ H + F C K F+ L+ H+ IH AD +++C CGK
Sbjct: 193 GNNFWNSSLLTQKQEVHMREKSFQCNESGKAFNYSSLLRKHQIIHLAD--KYKCDVCGKL 250
Query: 1267 FRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ- 1325
F ++ LA H+R H + P++C +CG+T+ SL HRR H TG+
Sbjct: 251 FNQKRNLACHRRCHTG-------------ENPYKCNECGKTFSQTSSLTCHRRLH-TGEK 296
Query: 1326 -YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLR 1384
Y C C K + + L+ H+ +H+E + +C CG++F + L RH R
Sbjct: 297 PYKCEECDKAFHFKSILERHRIIHTEEK----------PYKCNECGKTFRQKSILTRHHR 346
Query: 1385 EHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRPGERSQSPI 1444
H + N G T + +++LT L T G +P E G + S +
Sbjct: 347 LHTGEKPYKCNECGK---TFSHKSSLTCHHRLHT---GEKPYKCNECGKTFSHKSSLTCH 400
Query: 1445 RAASSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSPCHAGDCQ 1504
R + KA + N + R ED+ ++ C
Sbjct: 401 RRLHTGEKPYKCEECDKAYSFR-----SNFE-------IHRKIHTEDNAYK-------CN 441
Query: 1505 LNGPTLSHMDSWD-NRDNSSQLQPGSHSSCSQCGKTYCQSGSLLNHNTNKTDR--HYCLL 1561
G T S S +R + QP C +C K + +L H T + C
Sbjct: 442 ECGKTFSRTSSLTCHRRRHTGEQP---YKCEECDKAFRFKSNLERHRRIHTGEKPYKCNE 498
Query: 1562 CSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQVPAQMEEA 1621
C K F H H + + C +CGK F L H + H+ + P + +E
Sbjct: 499 CGKTFSRKSYLTCHHRLHTGEKAYKCNECGKTFSWKSSLTCHRRLHS---GEKPYKCKEC 555
Query: 1622 RDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVERARGGQAVTSMAAEDKERPFRCTQ 1681
T Q+ L + + + + + +E P++C +
Sbjct: 556 ----GKTFNQQLTLKRHRRLHSGENPYKCEDSDKAYSFKSNLEI-HQKIHTEENPYKCNE 610
Query: 1682 CGRSYRHAGSLLNHQKAHT-TGLYPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKA 1740
CG+++ SL H++ HT Y C C K +L+ H R HT K + C+ CGK
Sbjct: 611 CGKTFSRTSSLTCHRRLHTGEKPYKCEECDKAFRVKSNLEGHRRIHTGEKPYKCNECGKT 670
Query: 1741 FRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
F + H R+H E P+ C C ++F ++ S + H + H E
Sbjct: 671 FSRKSYFICHHRLHT-GEKPYKCNECGKNFSQKSSLICHHRLHTGE 715
Score = 152 bits (384), Expect = 3e-36
Identities = 144/626 (23%), Positives = 241/626 (38%), Gaps = 131/626 (20%)
Query: 823 CSDCGHSFPHATGLLSHRPCHPPGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFL 882
C++ G +F +++ L H+ H Y+C +C K F+ L H + H T P+
Sbjct: 217 CNESGKAFNYSSLLRKHQIIHLADKYKCDVCGKLFNQKRNLACHRRCH-----TGENPYK 271
Query: 883 CCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLN 942
C CG F + HRR GE+ E + +A
Sbjct: 272 CNECGKTFSQTSSLTCHRRL------------HTGEKPYKCE---------ECDKAFHFK 310
Query: 943 QLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEM 1002
+ + + + C CG+T+ L RHH+ T +K
Sbjct: 311 SILERHRIIHTEEKPYKCNECGKTFRQKSILTRHHRLH----TGEKPYK----------- 355
Query: 1003 VVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYR 1062
E G S + + T C L +P++CN+CGKT+
Sbjct: 356 -------------CNECGKTFSHKSSLT------C----HHRLHTGEKPYKCNECGKTFS 392
Query: 1063 HGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAAGS 1120
H SL HR++H TG+ + C C + Y + + H + H +E E G
Sbjct: 393 HKSSLTCHRRLH-TGEKPYKCEECDKAYSFRSNFEIHRKIH-----TEDNAYKCNEC-GK 445
Query: 1121 SELQVGPIPEGGSNKPQHMAEEGPGQAEVEK-------LQEELKVEPLEEVARVKEEVWE 1173
+ + + ++ +H E+ E +K L+ ++ E+ + E
Sbjct: 446 TFSRTSSLT---CHRRRHTGEQPYKCEECDKAFRFKSNLERHRRIHTGEKPYKCNECGKT 502
Query: 1174 ETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH-FGC 1232
+ RL T EK + C CG+++ SL HR+ H + C
Sbjct: 503 FSRKSYLTCHHRLHTGEKA----------YKCNECGKTFSWKSSLTCHRRLHSGEKPYKC 552
Query: 1233 QACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKA 1292
+ C K F+ ++LK HRR+H+ ++C + KA+ + L HQ++H
Sbjct: 553 KECGKTFNQQLTLKRHRRLHSGENPYKCEDSDKAYSFKSNLEIHQKIH------------ 600
Query: 1293 TREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSE 1350
E+ P++C +CG+T+ SL HRR H TG+ Y C C K + + L+ H+R+H+
Sbjct: 601 -TEENPYKCNECGKTFSRTSSLTCHRRLH-TGEKPYKCEECDKAFRVKSNLEGHRRIHTG 658
Query: 1351 NRRRRAGRSRRTAVR------------------CALCGRSFPGRGSLERHLREHEETERE 1392
+ + +T R C CG++F + SL H R H +
Sbjct: 659 EKPYKCNECGKTFSRKSYFICHHRLHTGEKPYKCNECGKNFSQKSSLICHHRLHTGEKPY 718
Query: 1393 PANGQGGLDGTAASEANLTGSQGLET 1418
N G T + ++NLT + L T
Sbjct: 719 KCNECG---KTFSQKSNLTCHRRLHT 741
Score = 144 bits (364), Expect = 6e-34
Identities = 123/466 (26%), Positives = 188/466 (40%), Gaps = 79/466 (16%)
Query: 235 EERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRP 293
EE+ YKC++CGKT++ LT H + HT Y C C K FS+ +L H RLH +P
Sbjct: 322 EEKPYKCNECGKTFRQKSILTRHHRLHTGEKPYKCNECGKTFSHKSSLTCHHRLHTGEKP 381
Query: 294 YHCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNG 353
Y C C + F L H++ H GE+ ++ A
Sbjct: 382 YKCNECGKTFSHKSSLTCHRRLHTGEK------------------PYKCEECDKAYSFRS 423
Query: 354 SAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLF 411
+ E+ ED+ ++C +CG+T+ SL HR+ H TG Y C C K
Sbjct: 424 NFEIHRKIHTEDNA------YKCNECGKTFSRTSSLTCHRRRH-TGEQPYKCEECDKAFR 476
Query: 412 NAAALKNHVRAH--HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSE 469
+ L+ H R H +P + E G+ + L H E + YKC+E
Sbjct: 477 FKSNLERHRRIHTGEKPYK-CNECGKTFSRKSYLTCHHRLHTGE---------KAYKCNE 526
Query: 470 CGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVH-------CKAARR 520
CG+ + + SL HR H +GE Y+C C + + + L+ H R+H C+ + +
Sbjct: 527 CGKTFSWKSSLTCHRRLH-SGEKPYKCKECGKTFNQQLTLKRHRRLHSGENPYKCEDSDK 585
Query: 521 SADIGAEGAPSHLKVELPPDPVEAEAAPHT--DQDHVCKHEEEATDITPAADKTAAHICS 578
+ H K+ +P + T + H T P + C
Sbjct: 586 AYSF-KSNLEIHQKIHTEENPYKCNECGKTFSRTSSLTCHRRLHTGEKP-------YKCE 637
Query: 579 ICGLLFEDAESLERHGLTHGAGEK-----ENSRTETTMS----------PPRAFACRDCG 623
C F +LE H H GEK E +T + S + + C +CG
Sbjct: 638 ECDKAFRVKSNLEGHRRIH-TGEKPYKCNECGKTFSRKSYFICHHRLHTGEKPYKCNECG 696
Query: 624 KSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHS 667
K++ SLI H + H TG+ + C C K F + + H R H+
Sbjct: 697 KNFSQKSSLICHHRLH-TGEKPYKCNECGKTFSQKSNLTCHRRLHT 741
Score = 141 bits (355), Expect = 7e-33
Identities = 126/540 (23%), Positives = 209/540 (38%), Gaps = 127/540 (23%)
Query: 821 HTCSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQ 879
+ C++CG +F + L H H Y+C+ C K F +L H + H T +
Sbjct: 326 YKCNECGKTFRQKSILTRHHRLHTGEKPYKCNECGKTFSHKSSLTCHHRLH-----TGEK 380
Query: 880 PFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAE 939
P+ C CG F ++ HRR E+ + E +A RS
Sbjct: 381 PYKCNECGKTFSHKSSLTCHRR--------LHTGEKPYKCEECDKAYSFRSN-------- 424
Query: 940 LLNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDA 999
++ R++ D+A + C CG+T+ SL H + + + P A
Sbjct: 425 --FEIHRKIHTEDNA---YKCNECGKTFSRTSSLTCHRRRHTG-----EQPYKCEECDKA 474
Query: 1000 MEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGK 1059
S LE +GE +P++CN+CGK
Sbjct: 475 FRF--KSNLERHRRIHTGE-------------------------------KPYKCNECGK 501
Query: 1060 TYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEA 1117
T+ L H ++H TG+ + C C + + ++++ L H R E
Sbjct: 502 TFSRKSYLTCHHRLH-TGEKAYKCNECGKTF----SWKSSLTCHRRLHSGE--------- 547
Query: 1118 AGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKEEVWEETTV 1177
KP E G + L+ ++ E + ++ +
Sbjct: 548 -----------------KPYKCKECGKTFNQQLTLKRHRRLHSGENPYKCEDSDKAYSFK 590
Query: 1178 KGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQAC 1235
EI ++ T E P+ C CG+++ SL HR+ H TG + C+ C
Sbjct: 591 SNLEIHQKIHT----------EENPYKCNECGKTFSRTSSLTCHRRLH-TGEKPYKCEEC 639
Query: 1236 SKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATRE 1295
K F +L+ HRRIH + ++C+ECGK F + H R+H
Sbjct: 640 DKAFRVKSNLEGHRRIHTGEKPYKCNECGKTFSRKSYFICHHRLHTG------------- 686
Query: 1296 DRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRR 1353
++P++C +CG+ + SL+ H R H TG+ Y C C KT+S + L H+RLH+ ++
Sbjct: 687 EKPYKCNECGKNFSQKSSLICHHRLH-TGEKPYKCNECGKTFSQKSNLTCHRRLHTGEKQ 745
Score = 134 bits (338), Expect = 6e-31
Identities = 110/445 (24%), Positives = 167/445 (37%), Gaps = 96/445 (21%)
Query: 236 ERRYKCSQCGKTYKHAGSLTNHRQSHTLGIYPCAICFKEFSNLMALKNHSRLHAQYRPYH 295
E+ ++C++ GK + ++ L H+ H Y C +C K F+ L H R H PY
Sbjct: 212 EKSFQCNESGKAFNYSSLLRKHQIIHLADKYKCDVCGKLFNQKRNLACHRRCHTGENPYK 271
Query: 296 CPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSA 355
C C + F L H++ H GE+ + E +L
Sbjct: 272 CNECGKTFSQTSSLTCHRRLHTGEKP--------------YKCEECDKAFHFKSILERHR 317
Query: 356 ELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFNA 413
+ T E +P++C +CG+T+R L H + H TG Y C+ C K +
Sbjct: 318 IIHT----------EEKPYKCNECGKTFRQKSILTRHHRLH-TGEKPYKCNECGKTFSHK 366
Query: 414 AALKNHVRAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRA 473
++L H R H GE +PYKC+ECG+
Sbjct: 367 SSLTCHHRLH------TGE------------------------------KPYKCNECGKT 390
Query: 474 YRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVHCK-AARRSADIG----- 525
+ H+ SL HR H TGE Y+C C + Y H ++H + A + + G
Sbjct: 391 FSHKSSLTCHRRLH-TGEKPYKCEECDKAYSFRSNFEIHRKIHTEDNAYKCNECGKTFSR 449
Query: 526 AEGAPSHLKVELPPDPVEAEAAPHT--DQDHVCKHEEEATDITPAADKTAAHICSICGLL 583
H + P + E + ++ +H T P + C+ CG
Sbjct: 450 TSSLTCHRRRHTGEQPYKCEECDKAFRFKSNLERHRRIHTGEKP-------YKCNECGKT 502
Query: 584 FEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQ-TG 642
F L H H GEK A+ C +CGK++ SL HR+ H
Sbjct: 503 FSRKSYLTCHHRLH-TGEK-------------AYKCNECGKTFSWKSSLTCHRRLHSGEK 548
Query: 643 DFSCGACAKHFHTMAAMKNHLRRHS 667
+ C C K F+ +K H R HS
Sbjct: 549 PYKCKECGKTFNQQLTLKRHRRLHS 573
Score = 111 bits (278), Expect = 6e-24
Identities = 62/209 (29%), Positives = 96/209 (45%), Gaps = 38/209 (18%)
Query: 1200 ERPFSCEVCGRSYKHAGSLINHRQSHQTGHFGCQACSKGFSNLMSLKNHRRIHADPRRFR 1259
E+ F C G+++ ++ L H+ H + C C K F+ +L HRR H ++
Sbjct: 212 EKSFQCNESGKAFNYSSLLRKHQIIHLADKYKCDVCGKLFNQKRNLACHRRCHTGENPYK 271
Query: 1260 CSECGKAFRLRKQLASHQRVH--------------------MERRGGGGTRKATREDRPF 1299
C+ECGK F L H+R+H +ER R E++P+
Sbjct: 272 CNECGKTFSQTSSLTCHRRLHTGEKPYKCEECDKAFHFKSILERH-----RIIHTEEKPY 326
Query: 1300 RCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAG 1357
+C +CG+T+R L H R H TG+ Y C C KT+S++ +L H RLH+ +
Sbjct: 327 KCNECGKTFRQKSILTRHHRLH-TGEKPYKCNECGKTFSHKSSLTCHHRLHTGEK----- 380
Query: 1358 RSRRTAVRCALCGRSFPGRGSLERHLREH 1386
+C CG++F + SL H R H
Sbjct: 381 -----PYKCNECGKTFSHKSSLTCHRRLH 404
Score = 102 bits (253), Expect = 4e-21
Identities = 105/425 (24%), Positives = 146/425 (34%), Gaps = 125/425 (29%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C++C + F L+ HR + +PY+C++C + +R +L HRR
Sbjct: 440 CNECGKTFSRTSSLTCHRR------------RHTGEQPYKCEECDKAFRFKSNLERHRRI 487
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHLQGETVSTDSW 127
H TG P C CGK FS L H R H E + E T SW
Sbjct: 488 H-TGEKPYKCNECGKTFSRKSYLTCHHRLHTGE-------------KAYKCNECGKTFSW 533
Query: 128 GQRLGSSEGWENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGADG 186
L ++ H+ E P C+ + L ++ L S P D
Sbjct: 534 KSSLTC-----HRRLHSGEKPYKCK-----ECGKTFNQQLTLKRHRRLHSGENPYKCEDS 583
Query: 187 WGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGK 246
A S SNLE + Q EE YKC++CGK
Sbjct: 584 --------------DKAYSFKSNLEIH---------------QKIHTEE-NPYKCNECGK 613
Query: 247 TYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRL 305
T+ SLT HR+ HT Y C C K F L+ H R+H +PY C C + F
Sbjct: 614 TFSRTSSLTCHRRLHTGEKPYKCEECDKAFRVKSNLEGHRRIHTGEKPYKCNECGKTFSR 673
Query: 306 PRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSGELED 365
+ H + H GE+
Sbjct: 674 KSYFICHHRLHTGEK--------------------------------------------- 688
Query: 366 SGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFNAAALKNHVRAH 423
P++C +CG+ + SLI H + H TG Y C+ C K + L H R H
Sbjct: 689 -------PYKCNECGKNFSQKSSLICHHRLH-TGEKPYKCNECGKTFSQKSNLTCHRRLH 740
Query: 424 HRPRQ 428
+Q
Sbjct: 741 TGEKQ 745
Score = 89.7 bits (221), Expect = 2e-17
Identities = 147/713 (20%), Positives = 250/713 (35%), Gaps = 141/713 (19%)
Query: 408 KQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKC 467
K + +A+ + R RP+ + N + + LL T K+E + + ++C
Sbjct: 166 KSVHDASLVSTAQRISCRPKTHISNNHGNNFWNSSLL----TQKQE----VHMREKSFQC 217
Query: 468 SECGRAYRHRGSLVNHRHSHRTGEYQCSLCPRKYPNLMALRNHVRVHCKAARRSADIGAE 527
+E G+A+ + L H+ H +Y+C +C + + L H R H
Sbjct: 218 NESGKAFNYSSLLRKHQIIHLADKYKCDVCGKLFNQKRNLACHRRCHTG----------- 266
Query: 528 GAPSHLKVELPPDPVEAEAAPHTDQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDA 587
E P E C H T P + C C F
Sbjct: 267 --------ENPYKCNECGKTFSQTSSLTC-HRRLHTGEKP-------YKCEECDKAFHFK 310
Query: 588 ESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FS 645
LERH + H + + + C +CGK++R L H + H TG+ +
Sbjct: 311 SILERHRIIH--------------TEEKPYKCNECGKTFRQKSILTRHHRLH-TGEKPYK 355
Query: 646 CGACAKHFHTMAAMKNHLRRHSRRRSRRHRKRAGGASGGREAKLLAAESWTRELEDNEGL 705
C C K F +++ H R H+ + ++ G + ++ L R L
Sbjct: 356 CNECGKTFSHKSSLTCHHRLHTGEKP--YKCNECGKTFSHKSSLTCH----RRLH----- 404
Query: 706 ESPQDPSGESPHGAEGNLESDGDCLQAESEGDKCGLERDETHFQGDKESGGTGEGLERKD 765
+GE P+ E +C +A S + R + G+ R
Sbjct: 405 ------TGEKPYKCE-------ECDKAYSFRSNFEIHRKIHTEDNAYKCNECGKTFSRTS 451
Query: 766 ASLLDNLDIPGEEGGGTHFCDSL----TGVDEDQKPATGQPNSSSHSANAVTGWQAGAAH 821
+ GE+ CD + ++ ++ TG+ +
Sbjct: 452 SLTCHRRRHTGEQPYKCEECDKAFRFKSNLERHRRIHTGEK-----------------PY 494
Query: 822 TCSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQP 880
C++CG +F + L H H Y+C+ C K F +L H + H + +P
Sbjct: 495 KCNECGKTFSRKSYLTCHHRLHTGEKAYKCNECGKTFSWKSSLTCHRRLH-----SGEKP 549
Query: 881 FLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAEL 940
+ C CG F + + HRR SG E+ ++ + S E+
Sbjct: 550 YKCKECGKTFNQQLTLKRHRRL---HSGENPYKCEDSDKAYSFK-----------SNLEI 595
Query: 941 LNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAM 1000
++ E + C CG+T+ SL H + + + P A
Sbjct: 596 HQKIHTEENP-------YKCNECGKTFSRTSSLTCHRRLHTG-----EKPYKCEECDKAF 643
Query: 1001 EMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKT 1060
V S LE +GE K E T S I L +P++CN+CGK
Sbjct: 644 R--VKSNLEGHRRIHTGEK-PYKCNECGKTFSRKSYFIC--HHRLHTGEKPYKCNECGKN 698
Query: 1061 YRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQV 1111
+ SL+ H ++H TG+ + C C + + + +++L H R E QV
Sbjct: 699 FSQKSSLICHHRLH-TGEKPYKCNECGKTF----SQKSNLTCHRRLHTGEKQV 746
Score = 57.4 bits (137), Expect = 1e-07
Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 15/93 (16%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C++C + F L+RH L + +PY+C +CG+ + H SL H R
Sbjct: 328 CNECGKTFRQKSILTRHHRL------------HTGEKPYKCNECGKTFSHKSSLTCHHRL 375
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPE 100
H TG P C CGK FS+ +L H R H E
Sbjct: 376 H-TGEKPYKCNECGKTFSHKSSLTCHRRLHTGE 407
Score = 57.0 bits (136), Expect = 2e-07
Identities = 34/93 (36%), Positives = 46/93 (49%), Gaps = 15/93 (16%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C + F L RHR ++H +EE +PY+C +CG+ +R L H R
Sbjct: 300 CEECDKAFHFKSILERHR-IIH------TEE-----KPYKCNECGKTFRQKSILTRHHRL 347
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPE 100
H TG P C CGK FS+ +L H R H E
Sbjct: 348 H-TGEKPYKCNECGKTFSHKSSLTCHHRLHTGE 379
Score = 48.5 bits (114), Expect = 6e-05
Identities = 30/120 (25%), Positives = 42/120 (35%), Gaps = 41/120 (34%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C++C + F L+ H L + +PY+C +CG+ + H SL HRR
Sbjct: 356 CNECGKTFSHKSSLTCHHRL------------HTGEKPYKCNECGKTFSHKSSLTCHRRL 403
Query: 70 H-----------------------------ETGLFPCTTCGKDFSNPMALKSHMRTHAPE 100
H E + C CGK FS +L H R H E
Sbjct: 404 HTGEKPYKCEECDKAYSFRSNFEIHRKIHTEDNAYKCNECGKTFSRTSSLTCHRRRHTGE 463
Score = 47.4 bits (111), Expect = 1e-04
Identities = 24/84 (28%), Positives = 36/84 (42%), Gaps = 3/84 (3%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C++CGKT+ + + H+ T + C C K F + H H + + C +C
Sbjct: 664 CNECGKTFSRKSYFICHHRLHTGEKPYKCNECGKNFSQKSSLICHHRLHTGEKPYKCNEC 723
Query: 1591 GKAFESHQELASHLQAHARGHSQV 1614
GK F L H + H G QV
Sbjct: 724 GKTFSQKSNLTCHRRLHT-GEKQV 746
Score = 43.1 bits (100), Expect = 0.002
Identities = 30/93 (32%), Positives = 37/93 (39%), Gaps = 15/93 (16%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C C + F L+ HR H N PY+C +CG+ + SL HRR
Sbjct: 244 CDVCGKLFNQKRNLACHRRC-HTGEN-----------PYKCNECGKTFSQTSSLTCHRRL 291
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPE 100
H TG P C C K F L+ H H E
Sbjct: 292 H-TGEKPYKCEECDKAFHFKSILERHRIIHTEE 323
Score = 38.1 bits (87), Expect = 0.079
Identities = 16/62 (25%), Positives = 27/62 (43%)
Query: 39 EEADSIPRPYRCQQCGRGYRHPGSLVNHRRTHETGLFPCTTCGKDFSNPMALKSHMRTHA 98
+E + ++C + G+ + + L H+ H + C CGK F+ L H R H
Sbjct: 206 QEVHMREKSFQCNESGKAFNYSSLLRKHQIIHLADKYKCDVCGKLFNQKRNLACHRRCHT 265
Query: 99 PE 100
E
Sbjct: 266 GE 267
>gi|55742736 zinc finger protein 700 [Homo sapiens]
Length = 742
Score = 163 bits (413), Expect = 1e-39
Identities = 145/630 (23%), Positives = 235/630 (37%), Gaps = 98/630 (15%)
Query: 1178 KGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQ-TGHFGCQACS 1236
K P + T E+ + + E+P++C+VCG+++ S+ H H G + C+ C
Sbjct: 173 KAFRYRPSIRTQER----DHTGEKPYACKVCGKTFIFHSSIRRHMVMHSGDGTYKCKFCG 228
Query: 1237 KGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATRED 1296
K F + H R H + + C +CGK+F L H+R H +
Sbjct: 229 KAFHSFSLYLIHERTHTGEKPYECKQCGKSFTYSATLQIHERTHTG-------------E 275
Query: 1297 RPFRCGQCGRTYRHAGSLLNHRRSHETGQ-YSCPTCPKTYSNRMALKDHQRLHSENRRRR 1355
+P+ C +C + + + S H RSH + Y C C K ++ +L+ H+R HS +
Sbjct: 276 KPYECSKCDKAFHSSSSYHRHERSHMGEKPYQCKECGKAFAYTSSLRRHERTHSGKKPYE 335
Query: 1356 AGR---------SRRTAVR---------CALCGRSFPGRGSLERHLREHEETEREPANGQ 1397
+ S +T +R C +CG+ F S + H + H +R
Sbjct: 336 CKQYGEGLSYLISFQTHIRMNSGERPYKCKICGKGFYSAKSFQTHEKTHTGEKRYKCKQC 395
Query: 1398 GGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRPGERSQSPIRAASSEAPEPLSW 1457
G NL+ S ++ E + SQ + + +P
Sbjct: 396 G-------KAFNLSSSFRYHERIHTGEKPYECKQCGKAFRSASQLRVHGGTHTGEKPYEC 448
Query: 1458 G-AGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSPCHAGDCQLNGPTLSHMDSW 1516
GKA + L H R+ E P +C + H+
Sbjct: 449 KECGKA--FRSTSHLRVHG---------RTHTGE-----KPYECKECGKAFRYVKHLQIH 492
Query: 1517 DNRDNSSQLQPGSHS-SCSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATK 1573
+ + ++ G CS C K + + S H T + C C K F + +
Sbjct: 493 ERTEKHIRMPSGERPYKCSICEKGFYSAKSFQTHEKTHTGEKPYECNQCGKAFRCCNSLR 552
Query: 1574 SHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQV 1633
H H + + C CGKAF S ASHL+ H R H TGE
Sbjct: 553 YHERTHTGEKPYECKQCGKAFRS----ASHLRMHERTH----------------TGEKPY 592
Query: 1634 VLPGQGKAQEAPSE--------TPRGPGESVERARGGQAVTSMAAEDK----ERPFRCTQ 1681
GKA S T P E + + ++ +++ ++ E+P+ C +
Sbjct: 593 ECKQCGKAFSCASNLRKHGRTHTGEKPYECKQCGKAFRSASNLQMHERTHTGEKPYECKE 652
Query: 1682 CGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKA 1740
C +++ S H++ H Y C C + L+ H+RTH K + C CGKA
Sbjct: 653 CEKAFCKFSSFQIHERKHRGEKPYECKHCGNGFTSAKILQIHARTHIGEKHYECKECGKA 712
Query: 1741 FRTAARLEGHGRVHAPREGPFTCPHCPRHF 1770
F + L H R H E P+ C C + F
Sbjct: 713 FNYFSSLHIHARTHM-GEKPYECKDCGKAF 741
Score = 160 bits (404), Expect = 1e-38
Identities = 154/631 (24%), Positives = 234/631 (37%), Gaps = 93/631 (14%)
Query: 1183 EPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH------------F 1230
+ RL EK E S F C G S N TGH +
Sbjct: 109 DDRLNFQEKKASPEVKSCDSFVCAEVGIG----NSSFNMSIRGDTGHKAYEYQEYGPKPY 164
Query: 1231 GCQACS--KGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGG 1288
CQ K F S++ R H + + C CGK F + H +H G G
Sbjct: 165 KCQQPKNKKAFRYRPSIRTQERDHTGEKPYACKVCGKTFIFHSSIRRHMVMH----SGDG 220
Query: 1289 TRKATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQR 1346
T ++C CG+ + L H R+H TG+ Y C C K+++ L+ H+R
Sbjct: 221 T---------YKCKFCGKAFHSFSLYLIHERTH-TGEKPYECKQCGKSFTYSATLQIHER 270
Query: 1347 LHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLER----HLREHEETEREPANGQGGLDG 1402
H+ + C+ C ++F S R H+ E +E
Sbjct: 271 THTGEK----------PYECSKCDKAFHSSSSYHRHERSHMGEKPYQCKECGKAFAYTSS 320
Query: 1403 TAASEANLTGSQGLETQLGGAEPVPHLEDGVPRPGERSQSPIRAASSEAPEPLSWGAGKA 1462
E +G + E + G E + +L Q+ IR S E P GK
Sbjct: 321 LRRHERTHSGKKPYECKQYG-EGLSYLIS--------FQTHIRMNSGERPYKCKI-CGK- 369
Query: 1463 GGWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSPCHAGDCQLNGPTLSHMDSWDNRDNS 1522
G + + E+ R C N LS + R ++
Sbjct: 370 -------------GFYSAKSFQTHEKTHTGEKRYKCKQCGKAFN---LSSSFRYHERIHT 413
Query: 1523 SQLQPGSHSSCSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHI 1580
+ C QCGK + + L H T + C C K F + + H H
Sbjct: 414 GE----KPYECKQCGKAFRSASQLRVHGGTHTGEKPYECKECGKAFRSTSHLRVHGRTHT 469
Query: 1581 DAQTFACPDCGKAFESHQELASHLQAHARGHSQVPAQMEEARDPKAGTGEDQVVLPGQGK 1640
+ + C +CGKAF HLQ H R + +M P + ++ +
Sbjct: 470 GEKPYECKECGKAFR----YVKHLQIHERTEKHI--RMPSGERPYKCSICEKGFYSAKSF 523
Query: 1641 AQEAPSETPRGPGESVERARGGQAVTSMAAEDK----ERPFRCTQCGRSYRHAGSLLNHQ 1696
+ T P E + + + S+ ++ E+P+ C QCG+++R A L H+
Sbjct: 524 QTHEKTHTGEKPYECNQCGKAFRCCNSLRYHERTHTGEKPYECKQCGKAFRSASHLRMHE 583
Query: 1697 KAHTTGL-YPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHA 1755
+ HT Y C C K +L+ H RTHT K + C CGKAFR+A+ L+ H R H
Sbjct: 584 RTHTGEKPYECKQCGKAFSCASNLRKHGRTHTGEKPYECKQCGKAFRSASNLQMHERTHT 643
Query: 1756 PREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
E P+ C C + F + SF H+++H+ E
Sbjct: 644 -GEKPYECKECEKAFCKFSSFQIHERKHRGE 673
Score = 152 bits (384), Expect = 3e-36
Identities = 147/595 (24%), Positives = 221/595 (37%), Gaps = 119/595 (20%)
Query: 821 HTCSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQ 879
+ C CG +F + + H H G Y+C C K F S H + H T +
Sbjct: 194 YACKVCGKTFIFHSSIRRHMVMHSGDGTYKCKFCGKAFHSFSLYLIHERTH-----TGEK 248
Query: 880 PFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAE 939
P+ C CG F A ++H R GE+ P + S+ +
Sbjct: 249 PYECKQCGKSFTYSATLQIHERT------------HTGEK------------PYECSKCD 284
Query: 940 LLNQLQREVEALDSAGYG---HICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVA 996
+ + G + C CG+ + SL RH ++ S K P
Sbjct: 285 KAFHSSSSYHRHERSHMGEKPYQCKECGKAFAYTSSLRRHERTHSG-----KKPYECKQY 339
Query: 997 GDAMEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQ 1056
G+ + ++ + + SGE RP++C
Sbjct: 340 GEGLSYLIS--FQTHIRMNSGE-------------------------------RPYKCKI 366
Query: 1057 CGKTYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSE-PQVGP 1113
CGK + S H K H TG+ + C C + + +++R H R H K E Q G
Sbjct: 367 CGKGFYSAKSFQTHEKTH-TGEKRYKCKQCGKAFNLSSSFRYHERIHTGEKPYECKQCGK 425
Query: 1114 IPEAAGSSELQVGPIPEGGSN---KPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKEE 1170
+A S+L+V GG++ KP E G L+ + E+ KE
Sbjct: 426 AFRSA--SQLRV----HGGTHTGEKPYECKECGKAFRSTSHLRVHGRTHTGEKPYECKEC 479
Query: 1171 VWEETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH- 1229
VK +I R E + S ERP+ C +C + + A S H ++H TG
Sbjct: 480 GKAFRYVKHLQIHERTEKHIR----MPSGERPYKCSICEKGFYSAKSFQTHEKTH-TGEK 534
Query: 1230 -FGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRG--- 1285
+ C C K F SL+ H R H + + C +CGKAFR L H+R H +
Sbjct: 535 PYECNQCGKAFRCCNSLRYHERTHTGEKPYECKQCGKAFRSASHLRMHERTHTGEKPYEC 594
Query: 1286 ---------GGGTRKATRE---DRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTC 1331
RK R ++P+ C QCG+ +R A +L H R+H TG+ Y C C
Sbjct: 595 KQCGKAFSCASNLRKHGRTHTGEKPYECKQCGKAFRSASNLQMHERTH-TGEKPYECKEC 653
Query: 1332 PKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREH 1386
K + + + H+R H + C CG F L+ H R H
Sbjct: 654 EKAFCKFSSFQIHERKHRGEK----------PYECKHCGNGFTSAKILQIHARTH 698
Score = 147 bits (371), Expect = 9e-35
Identities = 124/491 (25%), Positives = 209/491 (42%), Gaps = 70/491 (14%)
Query: 236 ERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPY 294
E+ Y+C QCGK++ ++ +L H ++HT Y C+ C K F + + H R H +PY
Sbjct: 247 EKPYECKQCGKSFTYSATLQIHERTHTGEKPYECSKCDKAFHSSSSYHRHERSHMGEKPY 306
Query: 295 HCPHCPRVFRLPRELLEHQQSHEGERQ-EPRWEEKGMP---TTNGHTDESSQDQLPSAQM 350
C C + F L H+++H G++ E + +G+ + H +S ++ ++
Sbjct: 307 QCKECGKAFAYTSSLRRHERTHSGKKPYECKQYGEGLSYLISFQTHIRMNSGERPYKCKI 366
Query: 351 LNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTGV--YPCSLCSK 408
+ S + + + ++C CG+ + + S H + H TG Y C C K
Sbjct: 367 CGKGFYSAKSFQTHEKTHTGEKRYKCKQCGKAFNLSSSFRYHERIH-TGEKPYECKQCGK 425
Query: 409 QLFNAAALKNHVRAH--HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYK 466
+A+ L+ H H +P + E G+ + L + TH E +PY+
Sbjct: 426 AFRSASQLRVHGGTHTGEKPYE-CKECGKAFRSTSHLRVHGRTHTGE---------KPYE 475
Query: 467 CSECGRAYRHRGSLVNHRHSHR-----TGE--YQCSLCPRKYPNLMALRNHVRVH----- 514
C ECG+A+R+ L H + + +GE Y+CS+C + + + + + H + H
Sbjct: 476 CKECGKAFRYVKHLQIHERTEKHIRMPSGERPYKCSICEKGFYSAKSFQTHEKTHTGEKP 535
Query: 515 -----CKAARRSADIGAEGAPSHLKVELPPDPVEAEAAPHT--DQDHVCKHEEEATDITP 567
C A R + H + P E + H+ HE T P
Sbjct: 536 YECNQCGKAFRCCN----SLRYHERTHTGEKPYECKQCGKAFRSASHLRMHERTHTGEKP 591
Query: 568 AADKTAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYR 627
+ C CG F A +L +HG TH GEK + C+ CGK++R
Sbjct: 592 -------YECKQCGKAFSCASNLRKHGRTH-TGEKP-------------YECKQCGKAFR 630
Query: 628 HSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHSRRRSRRHRKRAGGASGGR 685
+ +L H +TH TG+ + C C K F ++ + H R+H R K G +G
Sbjct: 631 SASNLQMHERTH-TGEKPYECKECEKAFCKFSSFQIHERKH-RGEKPYECKHCG--NGFT 686
Query: 686 EAKLLAAESWT 696
AK+L + T
Sbjct: 687 SAKILQIHART 697
Score = 146 bits (368), Expect = 2e-34
Identities = 167/666 (25%), Positives = 250/666 (37%), Gaps = 142/666 (21%)
Query: 45 PRPYRCQQCG--RGYRHPGSLVNHRRTHETGLFP--CTTCGKDFSNPMALKSHMRTHAPE 100
P+PY+CQQ + +R+ S+ R H TG P C CGK F +++ HM H+ +
Sbjct: 161 PKPYKCQQPKNKKAFRYRPSIRTQERDH-TGEKPYACKVCGKTFIFHSSIRRHMVMHSGD 219
Query: 101 G--------------------RRRHRPPRPKEATPHLQGETVSTDSWGQRLGSSEGWENQ 140
G R H +P E + T S ++
Sbjct: 220 GTYKCKFCGKAFHSFSLYLIHERTHTGEKPYECKQCGKSFTYSATL----------QIHE 269
Query: 141 TKHTEETPDCESVPDPRAASGTWEDLPTRQREGLASHPGPEDG-ADGWGPS------TNS 193
HT E P S D S + R G + E G A + S T+S
Sbjct: 270 RTHTGEKPYECSKCDKAFHSSSSYHRHERSHMGEKPYQCKECGKAFAYTSSLRRHERTHS 329
Query: 194 ARAPPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGKTYKHAGS 253
+ P LS L + ++ + G+ P YKC CGK + A S
Sbjct: 330 GKKPYECKQYGEGLSYLISF--QTHIRMNSGERP-----------YKCKICGKGFYSAKS 376
Query: 254 LTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEH 312
H ++HT Y C C K F+ + + H R+H +PY C C + FR +L H
Sbjct: 377 FQTHEKTHTGEKRYKCKQCGKAFNLSSSFRYHERIHTGEKPYECKQCGKAFRSASQLRVH 436
Query: 313 QQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYR 372
+H GE+ +E K + ++ L G +
Sbjct: 437 GGTHTGEKP---YECK-----------------ECGKAFRSTSHLRVHGRTHTG----EK 472
Query: 373 PFRCGDCGRTYRHAGSLINHRKSHQ-------TGVYPCSLCSKQLFNAAALKNHVRAH-- 423
P+ C +CG+ +R+ L H ++ + Y CS+C K ++A + + H + H
Sbjct: 473 PYECKECGKAFRYVKHLQIHERTEKHIRMPSGERPYKCSICEKGFYSAKSFQTHEKTHTG 532
Query: 424 HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNH 483
+P + + G+ L E TH E +PY+C +CG+A+R L H
Sbjct: 533 EKPYE-CNQCGKAFRCCNSLRYHERTHTGE---------KPYECKQCGKAFRSASHLRMH 582
Query: 484 RHSHRTGE--YQCSLCPRKYPNLMALRNHVRVH----------CKAARRSADIGAEGAPS 531
+H TGE Y+C C + + LR H R H C A RSA +
Sbjct: 583 ERTH-TGEKPYECKQCGKAFSCASNLRKHGRTHTGEKPYECKQCGKAFRSASNLQMHERT 641
Query: 532 HLKVELPPDPVEAEAA---PHTDQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAE 588
H E P + E E A + Q H KH E + C CG F A+
Sbjct: 642 HTG-EKPYECKECEKAFCKFSSFQIHERKHRGE-----------KPYECKHCGNGFTSAK 689
Query: 589 SLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQ-TGDFSCG 647
L+ H TH GEK + C++CGK++ + SL H +TH + C
Sbjct: 690 ILQIHARTH-IGEKH-------------YECKECGKAFNYFSSLHIHARTHMGEKPYECK 735
Query: 648 ACAKHF 653
C K F
Sbjct: 736 DCGKAF 741
Score = 119 bits (297), Expect = 4e-26
Identities = 94/368 (25%), Positives = 147/368 (39%), Gaps = 60/368 (16%)
Query: 1050 RPFRCNQCGKTYRHGGSLVNHRKIHQ-TGDFLCPVCSRCYPNLAAYRNHLRNHP-----R 1103
+P+ C CGKT+ S+ H +H G + C C + + + + Y H R H
Sbjct: 192 KPYACKVCGKTFIFHSSIRRHMVMHSGDGTYKCKFCGKAFHSFSLYLIHERTHTGEKPYE 251
Query: 1104 CK--------------------GSEP-QVGPIPEAAGSSELQVGPIPEGGSNKPQHMAEE 1142
CK G +P + +A SS KP E
Sbjct: 252 CKQCGKSFTYSATLQIHERTHTGEKPYECSKCDKAFHSSSSYHRHERSHMGEKPYQCKEC 311
Query: 1143 GPGQAEVEKLQEELKVEPLEEVARVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSERP 1202
G A L+ + ++ K+ + + + R+ S ERP
Sbjct: 312 GKAFAYTSSLRRHERTHSGKKPYECKQYGEGLSYLISFQTHIRMN----------SGERP 361
Query: 1203 FSCEVCGRSYKHAGSLINHRQSHQTG--HFGCQACSKGFSNLMSLKNHRRIHADPRRFRC 1260
+ C++CG+ + A S H ++H TG + C+ C K F+ S + H RIH + + C
Sbjct: 362 YKCKICGKGFYSAKSFQTHEKTH-TGEKRYKCKQCGKAFNLSSSFRYHERIHTGEKPYEC 420
Query: 1261 SECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRS 1320
+CGKAFR QL RVH GGT ++P+ C +CG+ +R L H R+
Sbjct: 421 KQCGKAFRSASQL----RVH------GGTHTG---EKPYECKECGKAFRSTSHLRVHGRT 467
Query: 1321 HETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGS 1378
H TG+ Y C C K + L+ H+R R R +C++C + F S
Sbjct: 468 H-TGEKPYECKECGKAFRYVKHLQIHERTEKHIRMPSGER----PYKCSICEKGFYSAKS 522
Query: 1379 LERHLREH 1386
+ H + H
Sbjct: 523 FQTHEKTH 530
Score = 102 bits (255), Expect = 3e-21
Identities = 108/450 (24%), Positives = 169/450 (37%), Gaps = 90/450 (20%)
Query: 273 KEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGE-RQEPRWEEKGMP 331
K F +++ R H +PY C C + F + H H G+ + ++ K
Sbjct: 173 KAFRYRPSIRTQERDHTGEKPYACKVCGKTFIFHSSIRRHMVMHSGDGTYKCKFCGKAFH 232
Query: 332 T-------TNGHTDESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYR 384
+ HT E + + SA L ++ + +P+ C C + +
Sbjct: 233 SFSLYLIHERTHTGEKPYECKQCGKSFTYSATL----QIHERTHTGEKPYECSKCDKAFH 288
Query: 385 HAGSLINHRKSHQ-TGVYPCSLCSKQLFNAAALKNHVRAHHRPR----QGVGENGQPSVP 439
+ S H +SH Y C C K ++L+ H R H + + GE
Sbjct: 289 SSSSYHRHERSHMGEKPYQCKECGKAFAYTSSLRRHERTHSGKKPYECKQYGEG------ 342
Query: 440 PAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLC 497
L++ TH RPYKC CG+ + S H +H TGE Y+C C
Sbjct: 343 -LSYLISFQTHIRMNS-----GERPYKCKICGKGFYSAKSFQTHEKTH-TGEKRYKCKQC 395
Query: 498 PRKYPNLMALRNHVRVHC-----------KAARRSADIGAEG------------------ 528
+ + + R H R+H KA R ++ + G
Sbjct: 396 GKAFNLSSSFRYHERIHTGEKPYECKQCGKAFRSASQLRVHGGTHTGEKPYECKECGKAF 455
Query: 529 -APSHLKV-------ELPPDPVEAEAAPHTDQDHVCKHEEEATDI-TPAADKTAAHICSI 579
+ SHL+V E P + E A H+ HE I P+ ++ + CSI
Sbjct: 456 RSTSHLRVHGRTHTGEKPYECKECGKA-FRYVKHLQIHERTEKHIRMPSGER--PYKCSI 512
Query: 580 CGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTH 639
C F A+S + H TH GEK + C CGK++R SL H +TH
Sbjct: 513 CEKGFYSAKSFQTHEKTH-TGEK-------------PYECNQCGKAFRCCNSLRYHERTH 558
Query: 640 QTGD--FSCGACAKHFHTMAAMKNHLRRHS 667
TG+ + C C K F + + ++ H R H+
Sbjct: 559 -TGEKPYECKQCGKAFRSASHLRMHERTHT 587
Score = 101 bits (252), Expect = 6e-21
Identities = 122/547 (22%), Positives = 193/547 (35%), Gaps = 114/547 (20%)
Query: 821 HTCSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQ 879
+ C CG SF ++ L H H Y+CS C K F S + H ++H GE +
Sbjct: 250 YECKQCGKSFTYSATLQIHERTHTGEKPYECSKCDKAFHSSSSYHRHERSHM-GE----K 304
Query: 880 PFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAE 939
P+ C CG F + R H R HS E + EG++
Sbjct: 305 PYQCKECGKAFAYTSSLRRHER-THSGKKPYECKQYG---EGLS---------------- 344
Query: 940 LLNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDA 999
L Q + ++S + C CG+ + S + H ++ + G K G A
Sbjct: 345 YLISFQTHIR-MNSGERPYKCKICGKGFYSAKSFQTHEKTHT-GEKRYKCKQ----CGKA 398
Query: 1000 MEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGK 1059
+ + +++ GE Q G L + GG E +P+ C +CGK
Sbjct: 399 FNLSSSFRYHERIHT--GEKPYECKQCGKAFRSASQLRVHGGTHTGE---KPYECKECGK 453
Query: 1060 TYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCK-------GSEPQ 1110
+R L H + H TG+ + C C + + Y HL+ H R + G P
Sbjct: 454 AFRSTSHLRVHGRTH-TGEKPYECKECGKAF----RYVKHLQIHERTEKHIRMPSGERPY 508
Query: 1111 VGPIPEAA--GSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVK 1168
I E + Q G KP + G L+ + E+ K
Sbjct: 509 KCSICEKGFYSAKSFQTHEKTHTGE-KPYECNQCGKAFRCCNSLRYHERTHTGEKPYECK 567
Query: 1169 EEVWEETTVKGEEIEPRLETAEKGCQTEA------------------SSERPFSCEVCGR 1210
+ + + R T EK + + + E+P+ C+ CG+
Sbjct: 568 QCGKAFRSASHLRMHERTHTGEKPYECKQCGKAFSCASNLRKHGRTHTGEKPYECKQCGK 627
Query: 1211 SYKHAGSLINHR------------------------QSHQTGHFG-----CQACSKGFSN 1241
+++ A +L H Q H+ H G C+ C GF++
Sbjct: 628 AFRSASNLQMHERTHTGEKPYECKECEKAFCKFSSFQIHERKHRGEKPYECKHCGNGFTS 687
Query: 1242 LMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRC 1301
L+ H R H + + C ECGKAF L H R HM ++P+ C
Sbjct: 688 AKILQIHARTHIGEKHYECKECGKAFNYFSSLHIHARTHM-------------GEKPYEC 734
Query: 1302 GQCGRTY 1308
CG+ +
Sbjct: 735 KDCGKAF 741
Score = 56.6 bits (135), Expect = 2e-07
Identities = 34/93 (36%), Positives = 43/93 (46%), Gaps = 15/93 (16%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
CS C++ F S H E+ + +PY C QCG+ +R SL H RT
Sbjct: 510 CSICEKGFYSAKSFQTH------------EKTHTGEKPYECNQCGKAFRCCNSLRYHERT 557
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPE 100
H TG P C CGK F + L+ H RTH E
Sbjct: 558 H-TGEKPYECKQCGKAFRSASHLRMHERTHTGE 589
Score = 53.1 bits (126), Expect = 2e-06
Identities = 32/93 (34%), Positives = 41/93 (44%), Gaps = 15/93 (16%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C C + F S L H E + +PY C+QCG+ + +L H RT
Sbjct: 566 CKQCGKAFRSASHLRMH------------ERTHTGEKPYECKQCGKAFSCASNLRKHGRT 613
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPE 100
H TG P C CGK F + L+ H RTH E
Sbjct: 614 H-TGEKPYECKQCGKAFRSASNLQMHERTHTGE 645
Score = 50.4 bits (119), Expect = 2e-05
Identities = 32/93 (34%), Positives = 42/93 (45%), Gaps = 15/93 (16%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C C + F +L R+ E +H +PY C+QCG+ +R L H T
Sbjct: 392 CKQCGKAF-NLSSSFRYHERIHTGE-----------KPYECKQCGKAFRSASQLRVHGGT 439
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPE 100
H TG P C CGK F + L+ H RTH E
Sbjct: 440 H-TGEKPYECKECGKAFRSTSHLRVHGRTHTGE 471
Score = 47.8 bits (112), Expect = 1e-04
Identities = 31/122 (25%), Positives = 46/122 (37%), Gaps = 41/122 (33%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
CS C + F S RH E + +PY+C++CG+ + + SL H RT
Sbjct: 280 CSKCDKAFHSSSSYHRH------------ERSHMGEKPYQCKECGKAFAYTSSLRRHERT 327
Query: 70 HE-----------TGL------------------FPCTTCGKDFSNPMALKSHMRTHAPE 100
H GL + C CGK F + + ++H +TH E
Sbjct: 328 HSGKKPYECKQYGEGLSYLISFQTHIRMNSGERPYKCKICGKGFYSAKSFQTHEKTHTGE 387
Query: 101 GR 102
R
Sbjct: 388 KR 389
Score = 47.8 bits (112), Expect = 1e-04
Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 9/93 (9%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C + F + L H + S RPY+C C +G+ S H +T
Sbjct: 476 CKECGKAFRYVKHLQIHER------TEKHIRMPSGERPYKCSICEKGFYSAKSFQTHEKT 529
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPE 100
H TG P C CGK F +L+ H RTH E
Sbjct: 530 H-TGEKPYECNQCGKAFRCCNSLRYHERTHTGE 561
Score = 47.0 bits (110), Expect = 2e-04
Identities = 31/109 (28%), Positives = 44/109 (40%), Gaps = 19/109 (17%)
Query: 10 CSDCQRHFPSLPELSRHRE----------------LLHPSPNQDSEEADSIPRPYRCQQC 53
C +C + F L RH L + Q +S RPY+C+ C
Sbjct: 308 CKECGKAFAYTSSLRRHERTHSGKKPYECKQYGEGLSYLISFQTHIRMNSGERPYKCKIC 367
Query: 54 GRGYRHPGSLVNHRRTHETG--LFPCTTCGKDFSNPMALKSHMRTHAPE 100
G+G+ S H +TH TG + C CGK F+ + + H R H E
Sbjct: 368 GKGFYSAKSFQTHEKTH-TGEKRYKCKQCGKAFNLSSSFRYHERIHTGE 415
Score = 45.4 bits (106), Expect = 5e-04
Identities = 28/93 (30%), Positives = 38/93 (40%), Gaps = 15/93 (16%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C C + F L +H + +PY C+QCG+ +R +L H RT
Sbjct: 594 CKQCGKAFSCASNLRKHGR------------THTGEKPYECKQCGKAFRSASNLQMHERT 641
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPE 100
H TG P C C K F + + H R H E
Sbjct: 642 H-TGEKPYECKECEKAFCKFSSFQIHERKHRGE 673
Score = 45.4 bits (106), Expect = 5e-04
Identities = 27/92 (29%), Positives = 36/92 (39%), Gaps = 13/92 (14%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C++ F H E +PY C+ CG G+ L H RT
Sbjct: 650 CKECEKAFCKFSSFQIH------------ERKHRGEKPYECKHCGNGFTSAKILQIHART 697
Query: 70 H-ETGLFPCTTCGKDFSNPMALKSHMRTHAPE 100
H + C CGK F+ +L H RTH E
Sbjct: 698 HIGEKHYECKECGKAFNYFSSLHIHARTHMGE 729
Score = 43.9 bits (102), Expect = 0.001
Identities = 24/90 (26%), Positives = 36/90 (40%), Gaps = 13/90 (14%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C C + F L H E + +PY C +C + + S H R+
Sbjct: 252 CKQCGKSFTYSATLQIH------------ERTHTGEKPYECSKCDKAFHSSSSYHRHERS 299
Query: 70 H-ETGLFPCTTCGKDFSNPMALKSHMRTHA 98
H + C CGK F+ +L+ H RTH+
Sbjct: 300 HMGEKPYQCKECGKAFAYTSSLRRHERTHS 329
>gi|209870092 hypothetical protein LOC345462 [Homo sapiens]
Length = 563
Score = 163 bits (412), Expect = 2e-39
Identities = 116/416 (27%), Positives = 179/416 (43%), Gaps = 72/416 (17%)
Query: 239 YKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCP 297
YKC+ CGK + H+ SL+ H++ HT +Y C C K FS +L H R+H +PY C
Sbjct: 204 YKCNICGKIFLHSSSLSKHQRIHTGEKLYKCKECRKAFSQSSSLTQHLRVHTGEKPYICS 263
Query: 298 HCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAEL 357
C + F L+ HQ+ H GER + +E G + GS+ L
Sbjct: 264 ECGKAFSFTTSLIGHQRMHTGERPY-KCKECG-------------------KTFKGSSSL 303
Query: 358 STSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFNAAA 415
+ + +P++C +CGR + SLI H + H TG Y C+ C K + +
Sbjct: 304 NNHQRIHTG----EKPYKCNECGRAFSQCSSLIQHHRIH-TGEKPYECTQCGKAFTSISR 358
Query: 416 LKNHVRAHHRPRQ-GVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAY 474
L H R H + E G+ + L++ + H E +PY C ECG+A+
Sbjct: 359 LSRHHRIHTGEKPFHCNECGKVFSYHSALIIHQRIHTGE---------KPYACKECGKAF 409
Query: 475 RHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVH-------CKAARRSADIG 525
+L+ H+ H TGE Y+C+ C + + + L H R+H CK + A
Sbjct: 410 SQSSALIQHQRIH-TGEKPYKCNECGKAFSWISRLNIHHRIHTGEKPYNCKECGK-AFSS 467
Query: 526 AEGAPSHLKVELPPDPVEAE--AAPHTDQDHVCKHEEEATDITPAADKTAAHICSICGLL 583
G +H K+ P + + +H+ T P + C +CG
Sbjct: 468 HSGVNTHRKIHTGEKPYKCNDCEKAFNQSSALIQHQRIHTGEKP-------YNCKVCGKA 520
Query: 584 FEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTH 639
F + SL H H GEK + C++CGK++ S SL NH++TH
Sbjct: 521 FRQSSSLMTHMRIH-TGEK-------------PYKCKECGKAFSQSSSLTNHQRTH 562
Score = 144 bits (364), Expect = 6e-34
Identities = 114/417 (27%), Positives = 178/417 (42%), Gaps = 70/417 (16%)
Query: 1203 FSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPRRFRC 1260
+ C +CG+ + H+ SL H++ H TG + C+ C K FS SL H R+H + + C
Sbjct: 204 YKCNICGKIFLHSSSLSKHQRIH-TGEKLYKCKECRKAFSQSSSLTQHLRVHTGEKPYIC 262
Query: 1261 SECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRS 1320
SECGKAF L HQR+H +RP++C +CG+T++ + SL NH+R
Sbjct: 263 SECGKAFSFTTSLIGHQRMH-------------TGERPYKCKECGKTFKGSSSLNNHQRI 309
Query: 1321 HETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGS 1378
H TG+ Y C C + +S +L H R+H+ + C CG++F
Sbjct: 310 H-TGEKPYKCNECGRAFSQCSSLIQHHRIHTGEK----------PYECTQCGKAFTSISR 358
Query: 1379 LERHLREHEETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRPGE 1438
L RH R H + N G + + + L Q + T G +P E G +
Sbjct: 359 LSRHHRIHTGEKPFHCNECGKV---FSYHSALIIHQRIHT---GEKPYACKECG--KAFS 410
Query: 1439 RSQSPI---RAASSEAPEPLSWGAGKAGGWPVGGGLGN--HSGGWVPQFLTRSEEPEDSV 1493
+S + I R + E P + GKA W + + H+G E+P
Sbjct: 411 QSSALIQHQRIHTGEKPYKCN-ECGKAFSWISRLNIHHRIHTG----------EKPY--- 456
Query: 1494 HRSPCHAGDCQLNGPTLSHMDSWDNRDNSSQLQPGSHS-SCSQCGKTYCQSGSLLNHNTN 1552
+C+ G S S + ++ G C+ C K + QS +L+ H
Sbjct: 457 --------NCKECGKAFS---SHSGVNTHRKIHTGEKPYKCNDCEKAFNQSSALIQHQRI 505
Query: 1553 KTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAH 1607
T + C +C K F + +H H + + C +CGKAF L +H + H
Sbjct: 506 HTGEKPYNCKVCGKAFRQSSSLMTHMRIHTGEKPYKCKECGKAFSQSSSLTNHQRTH 562
Score = 140 bits (353), Expect = 1e-32
Identities = 88/352 (25%), Positives = 148/352 (42%), Gaps = 72/352 (20%)
Query: 1041 GESLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHL 1098
G + RP++C +CGKT++ SL NH++IH TG+ + C C R + ++ H
Sbjct: 277 GHQRMHTGERPYKCKECGKTFKGSSSLNNHQRIH-TGEKPYKCNECGRAFSQCSSLIQHH 335
Query: 1099 RNHPRCKGSEPQVGPIPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKV 1158
R H KP + G + +L ++
Sbjct: 336 RIHT------------------------------GEKPYECTQCGKAFTSISRLSRHHRI 365
Query: 1159 EPLEEVARVKEEVWEETTVKGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSL 1218
E+ E + I R+ T EK P++C+ CG+++ + +L
Sbjct: 366 HTGEKPFHCNECGKVFSYHSALIIHQRIHTGEK----------PYACKECGKAFSQSSAL 415
Query: 1219 INHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASH 1276
I H++ H TG + C C K FS + L H RIH + + C ECGKAF + +H
Sbjct: 416 IQHQRIH-TGEKPYKCNECGKAFSWISRLNIHHRIHTGEKPYNCKECGKAFSSHSGVNTH 474
Query: 1277 QRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKT 1334
+++H ++P++C C + + + +L+ H+R H TG+ Y+C C K
Sbjct: 475 RKIH-------------TGEKPYKCNDCEKAFNQSSALIQHQRIH-TGEKPYNCKVCGKA 520
Query: 1335 YSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREH 1386
+ +L H R+H+ + +C CG++F SL H R H
Sbjct: 521 FRQSSSLMTHMRIHTGEK----------PYKCKECGKAFSQSSSLTNHQRTH 562
Score = 126 bits (317), Expect = 2e-28
Identities = 113/506 (22%), Positives = 184/506 (36%), Gaps = 152/506 (30%)
Query: 821 HTCSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQ 879
+ C+ CG F H++ L H+ H +Y+C C K F +L H + H T +
Sbjct: 204 YKCNICGKIFLHSSSLSKHQRIHTGEKLYKCKECRKAFSQSSSLTQHLRVH-----TGEK 258
Query: 880 PFLCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAE 939
P++C CG F H+R H+ + E +G +
Sbjct: 259 PYICSECGKAFSFTTSLIGHQRM-HTGERPYKCKECGKTFKG----------------SS 301
Query: 940 LLNQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDA 999
LN QR + + + C CG+ + SL +HH+ + + P G A
Sbjct: 302 SLNNHQR----IHTGEKPYKCNECGRAFSQCSSLIQHHRIHTG-----EKPYECTQCGKA 352
Query: 1000 MEMVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGK 1059
+ + L I GE +PF CN+CGK
Sbjct: 353 FTSI--------------------------SRLSRHHRIHTGE-------KPFHCNECGK 379
Query: 1060 TYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEA 1117
+ + +L+ H++IH TG+ + C C + + +A H R H
Sbjct: 380 VFSYHSALIIHQRIH-TGEKPYACKECGKAFSQSSALIQHQRIHT--------------- 423
Query: 1118 AGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKEEVWEETTV 1177
KP E G + + +L
Sbjct: 424 ---------------GEKPYKCNECGKAFSWISRL------------------------- 443
Query: 1178 KGEEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQAC 1235
I R+ T EK P++C+ CG+++ + HR+ H TG + C C
Sbjct: 444 ---NIHHRIHTGEK----------PYNCKECGKAFSSHSGVNTHRKIH-TGEKPYKCNDC 489
Query: 1236 SKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATRE 1295
K F+ +L H+RIH + + C CGKAFR L +H R+H
Sbjct: 490 EKAFNQSSALIQHQRIHTGEKPYNCKVCGKAFRQSSSLMTHMRIH-------------TG 536
Query: 1296 DRPFRCGQCGRTYRHAGSLLNHRRSH 1321
++P++C +CG+ + + SL NH+R+H
Sbjct: 537 EKPYKCKECGKAFSQSSSLTNHQRTH 562
Score = 120 bits (301), Expect = 1e-26
Identities = 120/464 (25%), Positives = 178/464 (38%), Gaps = 121/464 (26%)
Query: 30 LHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRTHETGLFP--CTTCGKDFSNP 87
LH S + + + Y+C++C + + SL H R H TG P C+ CGK FS
Sbjct: 214 LHSSSLSKHQRIHTGEKLYKCKECRKAFSQSSSLTQHLRVH-TGEKPYICSECGKAFSFT 272
Query: 88 MALKSHMRTHAPEGRRRHRPPRPKEATPHLQGETVSTDSWGQRLGSSEGWENQTKHTEET 147
+L H R H E RP + KE G+T GSS +Q HT E
Sbjct: 273 TSLIGHQRMHTGE-----RPYKCKEC-----GKTFK--------GSSSLNNHQRIHTGEK 314
Query: 148 P-DCESVPDPRAASGTWEDLPTRQREGLASHPGPEDGADGWGPSTNSARAPPLPIPASSL 206
P C RA S Q L H G + T + A +
Sbjct: 315 PYKCNEC--GRAFS---------QCSSLIQHHRIHTGEKPY-ECTQCGK-------AFTS 355
Query: 207 LSNLEQYLAESVVNFTGGQEPTQSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSHT-LGI 265
+S L ++ G++P + C++CGK + + +L H++ HT
Sbjct: 356 ISRLSRH-----HRIHTGEKP-----------FHCNECGKVFSYHSALIIHQRIHTGEKP 399
Query: 266 YPCAICFKEFSNLMALKNHSRLHAQYRPYHCPHCPRVFRLPRELLEHQQSHEGERQEPRW 325
Y C C K FS AL H R+H +PY C C + F L H + H GE+
Sbjct: 400 YACKECGKAFSQSSALIQHQRIHTGEKPYKCNECGKAFSWISRLNIHHRIHTGEKP---- 455
Query: 326 EEKGMPTTNGHTDESSQDQLPSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRH 385
+ + S +N ++ T GE +P++C DC + +
Sbjct: 456 ----------YNCKECGKAFSSHSGVNTHRKIHT-GE---------KPYKCNDCEKAFNQ 495
Query: 386 AGSLINHRKSHQTG--VYPCSLCSKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAPL 443
+ +LI H++ H TG Y C +C K +++L H+R H GE
Sbjct: 496 SSALIQHQRIH-TGEKPYNCKVCGKAFRQSSSLMTHMRIH------TGE----------- 537
Query: 444 LLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSH 487
+PYKC ECG+A+ SL NH+ +H
Sbjct: 538 -------------------KPYKCKECGKAFSQSSSLTNHQRTH 562
Score = 120 bits (300), Expect = 2e-26
Identities = 82/286 (28%), Positives = 130/286 (45%), Gaps = 43/286 (15%)
Query: 236 ERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPY 294
ER YKC +CGKT+K + SL NH++ HT Y C C + FS +L H R+H +PY
Sbjct: 285 ERPYKCKECGKTFKGSSSLNNHQRIHTGEKPYKCNECGRAFSQCSSLIQHHRIHTGEKPY 344
Query: 295 HCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQ-DQLPSAQMLNG 353
C C + F L H + H GE+ H +E + SA +++
Sbjct: 345 ECTQCGKAFTSISRLSRHHRIHTGEKP-------------FHCNECGKVFSYHSALIIH- 390
Query: 354 SAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLF 411
+ +GE +P+ C +CG+ + + +LI H++ H TG Y C+ C K
Sbjct: 391 --QRIHTGE---------KPYACKECGKAFSQSSALIQHQRIH-TGEKPYKCNECGKAFS 438
Query: 412 NAAALKNHVRAHHRPR-QGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSEC 470
+ L H R H + E G+ + + H E +PYKC++C
Sbjct: 439 WISRLNIHHRIHTGEKPYNCKECGKAFSSHSGVNTHRKIHTGE---------KPYKCNDC 489
Query: 471 GRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVH 514
+A+ +L+ H+ H TGE Y C +C + + +L H+R+H
Sbjct: 490 EKAFNQSSALIQHQRIH-TGEKPYNCKVCGKAFRQSSSLMTHMRIH 534
Score = 119 bits (297), Expect = 4e-26
Identities = 81/293 (27%), Positives = 121/293 (41%), Gaps = 57/293 (19%)
Query: 236 ERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPY 294
E+ YKC++CG+ + SL H + HT Y C C K F+++ L H R+H +P+
Sbjct: 313 EKPYKCNECGRAFSQCSSLIQHHRIHTGEKPYECTQCGKAFTSISRLSRHHRIHTGEKPF 372
Query: 295 HCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNG---------HTDESSQDQL 345
HC C +VF L+ HQ+ H GE+ +E G + HT E
Sbjct: 373 HCNECGKVFSYHSALIIHQRIHTGEKPY-ACKECGKAFSQSSALIQHQRIHTGEKPYKCN 431
Query: 346 PSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPC 403
+ + + L+ + +P+ C +CG+ + + HRK H TG Y C
Sbjct: 432 ECGKAFSWISRLNIHHRIHTG----EKPYNCKECGKAFSSHSGVNTHRKIH-TGEKPYKC 486
Query: 404 SLCSKQLFNAAALKNHVRAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHR 463
+ C K ++AL H R H GE +
Sbjct: 487 NDCEKAFNQSSALIQHQRIH------TGE------------------------------K 510
Query: 464 PYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVH 514
PY C CG+A+R SL+ H H TGE Y+C C + + +L NH R H
Sbjct: 511 PYNCKVCGKAFRQSSSLMTHMRIH-TGEKPYKCKECGKAFSQSSSLTNHQRTH 562
Score = 115 bits (289), Expect = 3e-25
Identities = 81/305 (26%), Positives = 122/305 (40%), Gaps = 44/305 (14%)
Query: 1499 HAGD----CQLNGPTLSHMDSWDNRDNSSQLQPGSHS-SCSQCGKTYCQSGSLLNHNTNK 1553
H G+ C+ G T S +N ++ G C++CG+ + Q SL+ H+
Sbjct: 282 HTGERPYKCKECGKTFKGSSSLNNHQ---RIHTGEKPYKCNECGRAFSQCSSLIQHHRIH 338
Query: 1554 TDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGH 1611
T + C C K F + H H + F C +CGK F H L H + H
Sbjct: 339 TGEKPYECTQCGKAFTSISRLSRHHRIHTGEKPFHCNECGKVFSYHSALIIHQRIH---- 394
Query: 1612 SQVPAQMEEARDPKAGTGEDQVVLPGQGKA--------QEAPSETPRGPGESVERARGGQ 1663
TGE GKA Q T P + E +
Sbjct: 395 ----------------TGEKPYACKECGKAFSQSSALIQHQRIHTGEKPYKCNECGKAFS 438
Query: 1664 AVTSMAAEDK----ERPFRCTQCGRSYRHAGSLLNHQKAHTTGL-YPCSLCPKLLPNLLS 1718
++ + + E+P+ C +CG+++ + H+K HT Y C+ C K +
Sbjct: 439 WISRLNIHHRIHTGEKPYNCKECGKAFSSHSGVNTHRKIHTGEKPYKCNDCEKAFNQSSA 498
Query: 1719 LKNHSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQ 1778
L H R HT K + C +CGKAFR ++ L H R+H E P+ C C + F + S
Sbjct: 499 LIQHQRIHTGEKPYNCKVCGKAFRQSSSLMTHMRIHT-GEKPYKCKECGKAFSQSSSLTN 557
Query: 1779 HQQQH 1783
HQ+ H
Sbjct: 558 HQRTH 562
Score = 110 bits (275), Expect = 1e-23
Identities = 77/280 (27%), Positives = 115/280 (41%), Gaps = 30/280 (10%)
Query: 1533 CSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKEFLNPVATKSHSHNHIDAQTFACPDC 1590
C +C K + QS SL H T + C C K F + H H + + C +C
Sbjct: 234 CKECRKAFSQSSSLTQHLRVHTGEKPYICSECGKAFSFTTSLIGHQRMHTGERPYKCKEC 293
Query: 1591 GKAFESHQELASHLQAH-----------ARGHSQVPAQMEEARDPKAGTGEDQVVLPGQG 1639
GK F+ L +H + H R SQ + ++ R TGE G
Sbjct: 294 GKTFKGSSSLNNHQRIHTGEKPYKCNECGRAFSQCSSLIQHHR---IHTGEKPYECTQCG 350
Query: 1640 KAQEAPSETPR----GPGESVERARGGQAVTS--------MAAEDKERPFRCTQCGRSYR 1687
KA + S R GE V S E+P+ C +CG+++
Sbjct: 351 KAFTSISRLSRHHRIHTGEKPFHCNECGKVFSYHSALIIHQRIHTGEKPYACKECGKAFS 410
Query: 1688 HAGSLLNHQKAHT-TGLYPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSICGKAFRTAAR 1746
+ +L+ HQ+ HT Y C+ C K + L H R HT K + C CGKAF + +
Sbjct: 411 QSSALIQHQRIHTGEKPYKCNECGKAFSWISRLNIHHRIHTGEKPYNCKECGKAFSSHSG 470
Query: 1747 LEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
+ H ++H E P+ C C + F + + +QHQ+ H E
Sbjct: 471 VNTHRKIHT-GEKPYKCNDCEKAFNQSSALIQHQRIHTGE 509
Score = 108 bits (271), Expect = 4e-23
Identities = 66/229 (28%), Positives = 96/229 (41%), Gaps = 38/229 (16%)
Query: 1559 CLLCSKEFLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQVPAQM 1618
C +C K FL+ + H H + + C +C KAF L HL+ H
Sbjct: 206 CNICGKIFLHSSSLSKHQRIHTGEKLYKCKECRKAFSQSSSLTQHLRVH----------- 254
Query: 1619 EEARDPKAGTGEDQVVLPGQGKAQEAPSETPRGPGESVERARGGQAVTSMAAEDKERPFR 1678
TGE + GKA + + ERP++
Sbjct: 255 ---------TGEKPYICSECGKAFSFTT----------------SLIGHQRMHTGERPYK 289
Query: 1679 CTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCSIC 1737
C +CG++++ + SL NHQ+ HT Y C+ C + SL H R HT K + C+ C
Sbjct: 290 CKECGKTFKGSSSLNNHQRIHTGEKPYKCNECGRAFSQCSSLIQHHRIHTGEKPYECTQC 349
Query: 1738 GKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
GKAF + +RL H R+H E PF C C + F + + HQ+ H E
Sbjct: 350 GKAFTSISRLSRHHRIHT-GEKPFHCNECGKVFSYHSALIIHQRIHTGE 397
Score = 101 bits (252), Expect = 6e-21
Identities = 84/325 (25%), Positives = 133/325 (40%), Gaps = 52/325 (16%)
Query: 374 FRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFNAAALKNHVRAHHRPRQGV- 430
++C CG+ + H+ SL H++ H TG +Y C C K +++L H+R H + +
Sbjct: 204 YKCNICGKIFLHSSSLSKHQRIH-TGEKLYKCKECRKAFSQSSSLTQHLRVHTGEKPYIC 262
Query: 431 GENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYRHRGSLVNHRHSHRTG 490
E G+ L+ + H E RPYKC ECG+ ++ SL NH+ H TG
Sbjct: 263 SECGKAFSFTTSLIGHQRMHTGE---------RPYKCKECGKTFKGSSSLNNHQRIH-TG 312
Query: 491 E--YQCSLCPRKYPNLMALRNHVRVH-------CKAARRSADIGAEGAPSHLKVELPPDP 541
E Y+C+ C R + +L H R+H C + A H ++ P
Sbjct: 313 EKPYKCNECGRAFSQCSSLIQHHRIHTGEKPYECTQCGK-AFTSISRLSRHHRIHTGEKP 371
Query: 542 VEAEAAPHTDQDH--VCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGA 599
H + H+ T P A C CG F + +L +H H
Sbjct: 372 FHCNECGKVFSYHSALIIHQRIHTGEKPYA-------CKECGKAFSQSSALIQHQRIH-T 423
Query: 600 GEKENSRTETTMS---------------PPRAFACRDCGKSYRHSGSLINHRQTHQTGD- 643
GEK E + + + C++CGK++ + HR+ H TG+
Sbjct: 424 GEKPYKCNECGKAFSWISRLNIHHRIHTGEKPYNCKECGKAFSSHSGVNTHRKIH-TGEK 482
Query: 644 -FSCGACAKHFHTMAAMKNHLRRHS 667
+ C C K F+ +A+ H R H+
Sbjct: 483 PYKCNDCEKAFNQSSALIQHQRIHT 507
Score = 90.5 bits (223), Expect = 1e-17
Identities = 59/200 (29%), Positives = 89/200 (44%), Gaps = 16/200 (8%)
Query: 236 ERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPY 294
E+ + C++CGK + + +L H++ HT Y C C K FS AL H R+H +PY
Sbjct: 369 EKPFHCNECGKVFSYHSALIIHQRIHTGEKPYACKECGKAFSQSSALIQHQRIHTGEKPY 428
Query: 295 HCPHCPRVFRLPRELLEHQQSHEGERQEPRWE-EKGMPTTNG-------HTDESSQDQLP 346
C C + F L H + H GE+ E K + +G HT E
Sbjct: 429 KCNECGKAFSWISRLNIHHRIHTGEKPYNCKECGKAFSSHSGVNTHRKIHTGEKPYKCND 488
Query: 347 SAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTGV--YPCS 404
+ N S+ L + +P+ C CG+ +R + SL+ H + H TG Y C
Sbjct: 489 CEKAFNQSSALIQHQRIHTGE----KPYNCKVCGKAFRQSSSLMTHMRIH-TGEKPYKCK 543
Query: 405 LCSKQLFNAAALKNHVRAHH 424
C K +++L NH R H+
Sbjct: 544 ECGKAFSQSSSLTNHQRTHN 563
Score = 85.5 bits (210), Expect = 4e-16
Identities = 44/111 (39%), Positives = 56/111 (50%), Gaps = 2/111 (1%)
Query: 1677 FRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLCPKLLPNLLSLKNHSRTHTDPKRHCCS 1735
++C CG+ + H+ SL HQ+ HT LY C C K SL H R HT K + CS
Sbjct: 204 YKCNICGKIFLHSSSLSKHQRIHTGEKLYKCKECRKAFSQSSSLTQHLRVHTGEKPYICS 263
Query: 1736 ICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
CGKAF L GH R+H E P+ C C + F+ S HQ+ H E
Sbjct: 264 ECGKAFSFTTSLIGHQRMHT-GERPYKCKECGKTFKGSSSLNNHQRIHTGE 313
Score = 72.0 bits (175), Expect = 5e-12
Identities = 78/350 (22%), Positives = 128/350 (36%), Gaps = 48/350 (13%)
Query: 577 CSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHR 636
C+ICG +F + SL +H H GEK + C++C K++ S SL H
Sbjct: 206 CNICGKIFLHSSSLSKHQRIH-TGEK-------------LYKCKECRKAFSQSSSLTQHL 251
Query: 637 QTHQTGD--FSCGACAKHFHTMAAMKNHLRRHSRRRSRRHRKRA----GGASGGREAKLL 690
+ H TG+ + C C K F ++ H R H+ R + ++ G +S ++
Sbjct: 252 RVH-TGEKPYICSECGKAFSFTTSLIGHQRMHTGERPYKCKECGKTFKGSSSLNNHQRIH 310
Query: 691 AAESWTRELEDNEGLESPQDPSGESPHGAEGNLESDGDCLQAESEGDKCG-LERDETHFQ 749
E + + NE + S H E +C Q L R
Sbjct: 311 TGE---KPYKCNECGRAFSQCSSLIQHHRIHTGEKPYECTQCGKAFTSISRLSRHHRIHT 367
Query: 750 GDK--ESGGTGEGLERKDASLLDNLDIPGEEGGGTHFC----DSLTGVDEDQKPATGQPN 803
G+K G+ A ++ GE+ C + + + Q+ TG+
Sbjct: 368 GEKPFHCNECGKVFSYHSALIIHQRIHTGEKPYACKECGKAFSQSSALIQHQRIHTGEKP 427
Query: 804 SSSHSANAVTGW-----------QAGAAHTCSDCGHSFPHATGLLSHRPCHP-PGIYQCS 851
+ W + C +CG +F +G+ +HR H Y+C+
Sbjct: 428 YKCNECGKAFSWISRLNIHHRIHTGEKPYNCKECGKAFSSHSGVNTHRKIHTGEKPYKCN 487
Query: 852 LCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRAGYRLHRR 901
C K F+ AL H + H T +P+ C +CG F + H R
Sbjct: 488 DCEKAFNQSSALIQHQRIH-----TGEKPYNCKVCGKAFRQSSSLMTHMR 532
Score = 67.8 bits (164), Expect = 9e-11
Identities = 69/275 (25%), Positives = 98/275 (35%), Gaps = 81/275 (29%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSI----------------PRPYRCQQC 53
C+ C + F S+ LSRH + E + +PY C++C
Sbjct: 346 CTQCGKAFTSISRLSRHHRIHTGEKPFHCNECGKVFSYHSALIIHQRIHTGEKPYACKEC 405
Query: 54 GRGYRHPGSLVNHRRTHETGLFP--CTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPK 111
G+ + +L+ H+R H TG P C CGK FS L H R H E +P K
Sbjct: 406 GKAFSQSSALIQHQRIH-TGEKPYKCNECGKAFSWISRLNIHHRIHTGE-----KPYNCK 459
Query: 112 EATPHLQGETVSTDSWGQRLGSSEGWENQTK-HTEETP----DCESVPDPRAASGTWEDL 166
E G+ S G K HT E P DCE
Sbjct: 460 EC--------------GKAFSSHSGVNTHRKIHTGEKPYKCNDCEKA------------- 492
Query: 167 PTRQREGLASHPGPEDGADGWGPSTNSARAPPLPIPASSLLSNLEQYLAESVVNFTGGQE 226
Q L H G + N +SSL++++ + TG
Sbjct: 493 -FNQSSALIQHQRIHTGEKPY----NCKVCGKAFRQSSSLMTHMRIH--------TG--- 536
Query: 227 PTQSPPAEEERRYKCSQCGKTYKHAGSLTNHRQSH 261
E+ YKC +CGK + + SLTNH+++H
Sbjct: 537 ---------EKPYKCKECGKAFSQSSSLTNHQRTH 562
Score = 53.5 bits (127), Expect = 2e-06
Identities = 31/93 (33%), Positives = 45/93 (48%), Gaps = 15/93 (16%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
CS+C + F L H+ + + RPY+C++CG+ ++ SL NH+R
Sbjct: 262 CSECGKAFSFTTSLIGHQRM------------HTGERPYKCKECGKTFKGSSSLNNHQRI 309
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPE 100
H TG P C CG+ FS +L H R H E
Sbjct: 310 H-TGEKPYKCNECGRAFSQCSSLIQHHRIHTGE 341
Score = 53.5 bits (127), Expect = 2e-06
Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 15/94 (15%)
Query: 9 SCSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRR 68
+C +C + F S ++ HR++ + +PY+C C + + +L+ H+R
Sbjct: 457 NCKECGKAFSSHSGVNTHRKI------------HTGEKPYKCNDCEKAFNQSSALIQHQR 504
Query: 69 THETGLFP--CTTCGKDFSNPMALKSHMRTHAPE 100
H TG P C CGK F +L +HMR H E
Sbjct: 505 IH-TGEKPYNCKVCGKAFRQSSSLMTHMRIHTGE 537
Score = 52.8 bits (125), Expect = 3e-06
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 15/93 (16%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C++ F L++H + + +PY C +CG+ + SL+ H+R
Sbjct: 234 CKECRKAFSQSSSLTQHLRV------------HTGEKPYICSECGKAFSFTTSLIGHQRM 281
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTHAPE 100
H TG P C CGK F +L +H R H E
Sbjct: 282 H-TGERPYKCKECGKTFKGSSSLNNHQRIHTGE 313
Score = 50.1 bits (118), Expect = 2e-05
Identities = 31/93 (33%), Positives = 39/93 (41%), Gaps = 15/93 (16%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C++C R F L +H + + +PY C QCG+ + L H R
Sbjct: 318 CNECGRAFSQCSSLIQHHRI------------HTGEKPYECTQCGKAFTSISRLSRHHRI 365
Query: 70 HETG--LFPCTTCGKDFSNPMALKSHMRTHAPE 100
H TG F C CGK FS AL H R H E
Sbjct: 366 H-TGEKPFHCNECGKVFSYHSALIIHQRIHTGE 397
Score = 47.8 bits (112), Expect = 1e-04
Identities = 23/61 (37%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 42 DSIPRPYRCQQCGRGYRHPGSLVNHRRTHETG--LFPCTTCGKDFSNPMALKSHMRTHAP 99
+++ + Y+C CG+ + H SL H+R H TG L+ C C K FS +L H+R H
Sbjct: 198 NTVRKCYKCNICGKIFLHSSSLSKHQRIH-TGEKLYKCKECRKAFSQSSSLTQHLRVHTG 256
Query: 100 E 100
E
Sbjct: 257 E 257
Score = 46.2 bits (108), Expect = 3e-04
Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 7/114 (6%)
Query: 1673 KERPFRCTQCGRSYRHAGSLLNHQKAHTTGLYPCSLCPKLLPNLLSLKNHSRTHTDPKRH 1732
KER F+ + G++ SL+ + + G P S +L L + +T K +
Sbjct: 151 KERSFKGVEFGKNLGLKSSLIRKPRIVSRGRRPRSQQYSVLFKQLGV------NTVRKCY 204
Query: 1733 CCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQQHQEE 1786
C+ICGK F ++ L H R+H E + C C + F + S QH + H E
Sbjct: 205 KCNICGKIFLHSSSLSKHQRIHT-GEKLYKCKECRKAFSQSSSLTQHLRVHTGE 257
Score = 43.5 bits (101), Expect = 0.002
Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 3/55 (5%)
Query: 615 RAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHS 667
+ + C CGK + HS SL H++ H TG+ + C C K F +++ HLR H+
Sbjct: 202 KCYKCNICGKIFLHSSSLSKHQRIH-TGEKLYKCKECRKAFSQSSSLTQHLRVHT 255
>gi|154091003 zinc finger protein 470 [Homo sapiens]
Length = 717
Score = 163 bits (412), Expect = 2e-39
Identities = 126/459 (27%), Positives = 193/459 (42%), Gaps = 64/459 (13%)
Query: 235 EERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRP 293
E++ KC+ C K + +LT H++ HT Y C C K FS L H R+H +P
Sbjct: 224 EKKLLKCNDCEKIFSKISTLTLHQRIHTGEKPYECIECGKAFSQSAHLAQHQRIHTGEKP 283
Query: 294 YHCPHCPRVFRLPRELLEHQQSHEGER-QEPRWEEKGMPT-------TNGHTDESSQDQL 345
+ C C + F L++HQ+ H GE+ + + K HT E + +
Sbjct: 284 FECTECGKAFSQNAHLVQHQRVHTGEKPYQCKQCNKAFSQLAHLAQHQRVHTGEKPYECI 343
Query: 346 PSAQMLNGSAELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTGVYP--C 403
+ + + L+ + RP+ C DCG+ +R SLI HR+ + TG P C
Sbjct: 344 ECGKAFSDCSSLAHHRRIHTG----KRPYECIDCGKAFRQNASLIRHRRYYHTGEKPFDC 399
Query: 404 SLCSKQLFNAAALKNHVRAH--HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLD 461
C K + L H R H RP + G+ + L + + H E
Sbjct: 400 IDCGKAFTDHIGLIQHKRTHTGERPYK-CNVCGKAFSHGSSLTVHQRIHTGE-------- 450
Query: 462 HRPYKCSECGRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVH----- 514
+PY+C+ C +A+ HRGSL H+ H TGE Y+C C + + L +H R+H
Sbjct: 451 -KPYECNICEKAFSHRGSLTLHQRVH-TGEKPYECKECGKAFRQSTHLAHHQRIHTGEKP 508
Query: 515 --CKAARRSADIGAEGAPSHLKVELPPDPVEAE--AAPHTDQDHVCKHEEEATDITPAAD 570
CK ++ A A H K+ P E + + H+ +H+ T P
Sbjct: 509 YECKECSKTFSQNAHLA-QHQKIHTGEKPYECKECGKAFSQIAHLVQHQRVHTGEKP--- 564
Query: 571 KTAAHICSICGLLFEDAESLERHGLTHGAGEKENSRTETTMSPPRAFACRDCGKSYRHSG 630
+ C CG F D L +H H S R + C +CGK++R
Sbjct: 565 ----YECIECGKAFSDGSYLVQHQRLH--------------SGKRPYECLECGKAFRQRA 606
Query: 631 SLINHRQTHQTGD--FSCGACAKHFHTMAAMKNHLRRHS 667
SLI H++ H TG+ + C C K F ++ H R H+
Sbjct: 607 SLICHQRCH-TGEKPYECNVCGKAFSHRKSLTLHQRIHT 644
Score = 152 bits (385), Expect = 2e-36
Identities = 143/553 (25%), Positives = 216/553 (39%), Gaps = 76/553 (13%)
Query: 1270 RKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGSLLNHRRSHETGQ--YS 1327
+K L +H V ++ G E + +C C + + +L H+R H TG+ Y
Sbjct: 206 KKSLKTHSVVKKHKQDRG-------EKKLLKCNDCEKIFSKISTLTLHQRIH-TGEKPYE 257
Query: 1328 CPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSFPGRGSLERHLREHE 1387
C C K +S L HQR+H+ + C CG++F L +H R H
Sbjct: 258 CIECGKAFSQSAHLAQHQRIHTGEK----------PFECTECGKAFSQNAHLVQHQRVH- 306
Query: 1388 ETEREPANGQGGLDGTAASEANLTGSQGLETQLGGAEPVPHLEDGVPRPGERSQSPIRAA 1447
T +P + + + A+L Q + T G +P +E G S + R
Sbjct: 307 -TGEKPYQCKQ-CNKAFSQLAHLAQHQRVHT---GEKPYECIECGKAFSDCSSLAHHRRI 361
Query: 1448 SSEAPEPLSWGAGKAGGWPVGGGLGNHSGGWVPQFLTRSEEPEDSVHRSPCHAGDCQLNG 1507
+ GKA + L H ++ E+P D + DC
Sbjct: 362 HTGKRPYECIDCGKA--FRQNASLIRHR-----RYYHTGEKPFDCI--------DC--GK 404
Query: 1508 PTLSHMDSWDNRDNSSQLQPGSHSSCSQCGKTYCQSGSLLNHNTNKTDR--HYCLLCSKE 1565
H+ ++ + +P C+ CGK + SL H T + C +C K
Sbjct: 405 AFTDHIGLIQHKRTHTGERP---YKCNVCGKAFSHGSSLTVHQRIHTGEKPYECNICEKA 461
Query: 1566 FLNPVATKSHSHNHIDAQTFACPDCGKAFESHQELASHLQAHARGHSQVPAQMEE----- 1620
F + + H H + + C +CGKAF LA H + H + P + +E
Sbjct: 462 FSHRGSLTLHQRVHTGEKPYECKECGKAFRQSTHLAHHQRIHT---GEKPYECKECSKTF 518
Query: 1621 ------ARDPKAGTGEDQVVLPGQGKA--------QEAPSETPRGPGESVERAR----GG 1662
A+ K TGE GKA Q T P E +E + G
Sbjct: 519 SQNAHLAQHQKIHTGEKPYECKECGKAFSQIAHLVQHQRVHTGEKPYECIECGKAFSDGS 578
Query: 1663 QAVTSMAAEDKERPFRCTQCGRSYRHAGSLLNHQKAHT-TGLYPCSLCPKLLPNLLSLKN 1721
V +RP+ C +CG+++R SL+ HQ+ HT Y C++C K + SL
Sbjct: 579 YLVQHQRLHSGKRPYECLECGKAFRQRASLICHQRCHTGEKPYECNVCGKAFSHRKSLTL 638
Query: 1722 HSRTHTDPKRHCCSICGKAFRTAARLEGHGRVHAPREGPFTCPHCPRHFRRRISFVQHQQ 1781
H R HT K + C C KAF A L H R+H E P+ C C + FR+ + HQ+
Sbjct: 639 HQRIHTGEKPYECKECSKAFSQVAHLTLHKRIHT-GERPYECKECGKAFRQSVHLAHHQR 697
Query: 1782 QHQEEWTVAGSGA 1794
H E +V S A
Sbjct: 698 IHTGESSVILSSA 710
Score = 152 bits (384), Expect = 3e-36
Identities = 138/571 (24%), Positives = 215/571 (37%), Gaps = 108/571 (18%)
Query: 823 CSDCGHSFPHATGLLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPF 881
C+DC F + L H+ H Y+C C K F L H + H T +PF
Sbjct: 230 CNDCEKIFSKISTLTLHQRIHTGEKPYECIECGKAFSQSAHLAQHQRIH-----TGEKPF 284
Query: 882 LCCLCGMIFPGRAGYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELL 941
C CG F A H+R H+ + + A S L++ + +
Sbjct: 285 ECTECGKAFSQNAHLVQHQR-VHTGEKPYQ----------CKQCNKAFSQLAHLAQHQRV 333
Query: 942 NQLQREVEALDSAGYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAME 1001
+ ++ E ++ CG+ + D SL H + + K P G A
Sbjct: 334 HTGEKPYECIE----------CGKAFSDCSSLAHHRRIHTG-----KRPYECIDCGKAFR 378
Query: 1002 MVVDSVLEDIVNSVSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTY 1061
+ + D G D + + + + RP++CN CGK +
Sbjct: 379 QNASLIRHRRYYHTGEKPFDCID---CGKAFTDHIGLIQHKRTHTGE-RPYKCNVCGKAF 434
Query: 1062 RHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQVGPIPEAAG 1119
HG SL H++IH TG+ + C +C + + + + H R H
Sbjct: 435 SHGSSLTVHQRIH-TGEKPYECNICEKAFSHRGSLTLHQRVHT----------------- 476
Query: 1120 SSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKEEVWEETTVKG 1179
KP E G + L ++ E+ KE +T +
Sbjct: 477 -------------GEKPYECKECGKAFRQSTHLAHHQRIHTGEKPYECKE--CSKTFSQN 521
Query: 1180 EEIEPRLETAEKGCQTEASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSK 1237
+ Q + E+P+ C+ CG+++ L+ H++ H TG + C C K
Sbjct: 522 AHLAQH--------QKIHTGEKPYECKECGKAFSQIAHLVQHQRVH-TGEKPYECIECGK 572
Query: 1238 GFSNLMSLKNHRRIHADPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDR 1297
FS+ L H+R+H+ R + C ECGKAFR R L HQR H ++
Sbjct: 573 AFSDGSYLVQHQRLHSGKRPYECLECGKAFRQRASLICHQRCH-------------TGEK 619
Query: 1298 PFRCGQCGRTYRHAGSLLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRR 1355
P+ C CG+ + H SL H+R H TG+ Y C C K +S L H+R+H+ R
Sbjct: 620 PYECNVCGKAFSHRKSLTLHQRIH-TGEKPYECKECSKAFSQVAHLTLHKRIHTGER--- 675
Query: 1356 AGRSRRTAVRCALCGRSFPGRGSLERHLREH 1386
C CG++F L H R H
Sbjct: 676 -------PYECKECGKAFRQSVHLAHHQRIH 699
Score = 135 bits (341), Expect = 3e-31
Identities = 92/286 (32%), Positives = 133/286 (46%), Gaps = 43/286 (15%)
Query: 236 ERRYKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPY 294
ER YKC+ CGK + H SLT H++ HT Y C IC K FS+ +L H R+H +PY
Sbjct: 422 ERPYKCNVCGKAFSHGSSLTVHQRIHTGEKPYECNICEKAFSHRGSLTLHQRVHTGEKPY 481
Query: 295 HCPHCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGS 354
C C + FR L HQ+ H GE+ E + N H L Q ++
Sbjct: 482 ECKECGKAFRQSTHLAHHQRIHTGEKPYECKECSKTFSQNAH--------LAQHQKIH-- 531
Query: 355 AELSTSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFN 412
+GE +P+ C +CG+ + L+ H++ H TG Y C C K +
Sbjct: 532 -----TGE---------KPYECKECGKAFSQIAHLVQHQRVH-TGEKPYECIECGKAFSD 576
Query: 413 AAALKNHVRAH--HRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSEC 470
+ L H R H RP + + E G+ A L+ + H E +PY+C+ C
Sbjct: 577 GSYLVQHQRLHSGKRPYECL-ECGKAFRQRASLICHQRCHTGE---------KPYECNVC 626
Query: 471 GRAYRHRGSLVNHRHSHRTGE--YQCSLCPRKYPNLMALRNHVRVH 514
G+A+ HR SL H+ H TGE Y+C C + + + L H R+H
Sbjct: 627 GKAFSHRKSLTLHQRIH-TGEKPYECKECSKAFSQVAHLTLHKRIH 671
Score = 134 bits (336), Expect = 1e-30
Identities = 129/496 (26%), Positives = 177/496 (35%), Gaps = 149/496 (30%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C +C + F L+ HR + + RPY C CG+ +R SL+ HRR
Sbjct: 342 CIECGKAFSDCSSLAHHRRI------------HTGKRPYECIDCGKAFRQNASLIRHRRY 389
Query: 70 HETG--LFPCTTCGKDFSNPMALKSHMRTHAPEGRRRHRPPRPKEATPHLQGETVSTDSW 127
+ TG F C CGK F++ + L H RTH G R ++ +A H TV
Sbjct: 390 YHTGEKPFDCIDCGKAFTDHIGLIQHKRTHT--GERPYKCNVCGKAFSHGSSLTV----- 442
Query: 128 GQRLGSSEGWENQTKHTEETP-DCESVPDPRAASGTWEDLPTRQREGLASHPGP-EDGAD 185
+Q HT E P +C + G+ L QR P ++
Sbjct: 443 -----------HQRIHTGEKPYECNICEKAFSHRGS---LTLHQRVHTGEKPYECKECGK 488
Query: 186 GWGPSTNSAR-------APPLPIPASSLLSNLEQYLAESVVNFTGGQEPTQSPPAEEERR 238
+ ST+ A P S + +LA+ TG E+
Sbjct: 489 AFRQSTHLAHHQRIHTGEKPYECKECSKTFSQNAHLAQHQKIHTG------------EKP 536
Query: 239 YKCSQCGKTYKHAGSLTNHRQSHT-LGIYPCAICFKEFSNLMALKNHSRLHAQYRPYHCP 297
Y+C +CGK + L H++ HT Y C C K FS+ L H RLH+ RPY C
Sbjct: 537 YECKECGKAFSQIAHLVQHQRVHTGEKPYECIECGKAFSDGSYLVQHQRLHSGKRPYECL 596
Query: 298 HCPRVFRLPRELLEHQQSHEGERQEPRWEEKGMPTTNGHTDESSQDQLPSAQMLNGSAEL 357
C + FR L+ HQ+ H GE+
Sbjct: 597 ECGKAFRQRASLICHQRCHTGEK------------------------------------- 619
Query: 358 STSGELEDSGLEEYRPFRCGDCGRTYRHAGSLINHRKSHQTG--VYPCSLCSKQLFNAAA 415
P+ C CG+ + H SL H++ H TG Y C CSK A
Sbjct: 620 ---------------PYECNVCGKAFSHRKSLTLHQRIH-TGEKPYECKECSKAFSQVAH 663
Query: 416 LKNHVRAHHRPRQGVGENGQPSVPPAPLLLAETTHKEEEDPTTTLDHRPYKCSECGRAYR 475
L H R H GE RPY+C ECG+A+R
Sbjct: 664 LTLHKRIH------TGE------------------------------RPYECKECGKAFR 687
Query: 476 HRGSLVNHRHSHRTGE 491
L +H+ H TGE
Sbjct: 688 QSVHLAHHQRIH-TGE 702
Score = 124 bits (311), Expect = 8e-28
Identities = 96/373 (25%), Positives = 152/373 (40%), Gaps = 81/373 (21%)
Query: 1053 RCNQCGKTYRHGGSLVNHRKIHQTGD--FLCPVCSRCYPNLAAYRNHLRNHPRCKGSEPQ 1110
+CN C K + +L H++IH TG+ + C C + + A HL H R E
Sbjct: 229 KCNDCEKIFSKISTLTLHQRIH-TGEKPYECIECGKAFSQSA----HLAQHQRIHTGE-- 281
Query: 1111 VGPIPEAAGSSELQVGPIPEGGSNKPQHMAEEGPGQAEVEKLQEELKVEPLEEVARVKEE 1170
KP E G ++ L + +V E+ + K+
Sbjct: 282 ------------------------KPFECTECGKAFSQNAHLVQHQRVHTGEKPYQCKQC 317
Query: 1171 VWEETTVKGEEIEPRLETAEK------------GCQTEA------SSERPFSCEVCGRSY 1212
+ + R+ T EK C + A + +RP+ C CG+++
Sbjct: 318 NKAFSQLAHLAQHQRVHTGEKPYECIECGKAFSDCSSLAHHRRIHTGKRPYECIDCGKAF 377
Query: 1213 KHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHADPRRFRCSECGKAFRLR 1270
+ SLI HR+ + TG F C C K F++ + L H+R H R ++C+ CGKAF
Sbjct: 378 RQNASLIRHRRYYHTGEKPFDCIDCGKAFTDHIGLIQHKRTHTGERPYKCNVCGKAFSHG 437
Query: 1271 KQLASHQRVH--------------MERRGGGGTRKATRE-DRPFRCGQCGRTYRHAGSLL 1315
L HQR+H RG + ++P+ C +CG+ +R + L
Sbjct: 438 SSLTVHQRIHTGEKPYECNICEKAFSHRGSLTLHQRVHTGEKPYECKECGKAFRQSTHLA 497
Query: 1316 NHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGRSF 1373
+H+R H TG+ Y C C KT+S L HQ++H+ + C CG++F
Sbjct: 498 HHQRIH-TGEKPYECKECSKTFSQNAHLAQHQKIHTGEK----------PYECKECGKAF 546
Query: 1374 PGRGSLERHLREH 1386
L +H R H
Sbjct: 547 SQIAHLVQHQRVH 559
Score = 104 bits (259), Expect = 9e-22
Identities = 61/200 (30%), Positives = 91/200 (45%), Gaps = 29/200 (14%)
Query: 1196 EASSERPFSCEVCGRSYKHAGSLINHRQSHQTGH--FGCQACSKGFSNLMSLKNHRRIHA 1253
+ ++ C C + + +L H++ H TG + C C K FS L H+RIH
Sbjct: 221 DRGEKKLLKCNDCEKIFSKISTLTLHQRIH-TGEKPYECIECGKAFSQSAHLAQHQRIHT 279
Query: 1254 DPRRFRCSECGKAFRLRKQLASHQRVHMERRGGGGTRKATREDRPFRCGQCGRTYRHAGS 1313
+ F C+ECGKAF L HQRVH ++P++C QC + +
Sbjct: 280 GEKPFECTECGKAFSQNAHLVQHQRVH-------------TGEKPYQCKQCNKAFSQLAH 326
Query: 1314 LLNHRRSHETGQ--YSCPTCPKTYSNRMALKDHQRLHSENRRRRAGRSRRTAVRCALCGR 1371
L H+R H TG+ Y C C K +S+ +L H+R+H+ R C CG+
Sbjct: 327 LAQHQRVH-TGEKPYECIECGKAFSDCSSLAHHRRIHTGKR----------PYECIDCGK 375
Query: 1372 SFPGRGSLERHLREHEETER 1391
+F SL RH R + E+
Sbjct: 376 AFRQNASLIRHRRYYHTGEK 395
Score = 73.9 bits (180), Expect = 1e-12
Identities = 122/604 (20%), Positives = 209/604 (34%), Gaps = 127/604 (21%)
Query: 484 RHSHRTGE---YQCSLCPRKYPNLMALRNHVRVHCKAARRSADIGAEGAPSHLKVELPPD 540
+H GE +C+ C + + + L H R+H E P +
Sbjct: 217 KHKQDRGEKKLLKCNDCEKIFSKISTLTLHQRIHTG-------------------EKPYE 257
Query: 541 PVEAEAAPHTDQDHVCKHEEEATDITPAADKTAAHICSICGLLFEDAESLERHGLTHGAG 600
+E A + H+ +H+ T P C+ CG F L +H H G
Sbjct: 258 CIECGKA-FSQSAHLAQHQRIHTGEKPFE-------CTECGKAFSQNAHLVQHQRVH-TG 308
Query: 601 EKENSRTETTMSPPRAFACRDCGKSYRHSGSLINHRQTHQTGD--FSCGACAKHFHTMAA 658
EK + C+ C K++ L H++ H TG+ + C C K F ++
Sbjct: 309 EKP-------------YQCKQCNKAFSQLAHLAQHQRVH-TGEKPYECIECGKAFSDCSS 354
Query: 659 MKNHLRRHSRRRSRRHRKRAGGASGGREAKLLAAESWTRELEDNEGLESPQDPSGESPHG 718
+ +H R H+ +R + G + + A L+ + +GE P
Sbjct: 355 LAHHRRIHTGKRP--YECIDCGKAFRQNASLIRHRRYYH--------------TGEKPF- 397
Query: 719 AEGNLESDGDCLQ-AESEGDKCGLERDETHFQGDK--ESGGTGEGLERKDASLLDNLDIP 775
DC+ ++ D GL + + G++ + G+ + +
Sbjct: 398 ---------DCIDCGKAFTDHIGLIQHKRTHTGERPYKCNVCGKAFSHGSSLTVHQRIHT 448
Query: 776 GEEGGGTHFCDSLTGVDEDQKPATGQPNSSSHSANAVTGWQAGAAHTCSDCGHSFPHATG 835
GE+ + C+ A S + TG + + C +CG +F +T
Sbjct: 449 GEKPYECNICEK----------AFSHRGSLTLHQRVHTGEK---PYECKECGKAFRQSTH 495
Query: 836 LLSHRPCHP-PGIYQCSLCPKEFDSLPALRSHFQNHRPGEATSAQPFLCCLCGMIFPGRA 894
L H+ H Y+C C K F L H + H T +P+ C CG F A
Sbjct: 496 LAHHQRIHTGEKPYECKECSKTFSQNAHLAQHQKIH-----TGEKPYECKECGKAFSQIA 550
Query: 895 GYRLHRRQAHSSSGMTEGSEEEGEEEGVAEAAPARSPPLQLSEAELLNQLQREVEALDSA 954
H+R H+ E E A S L + + L+ +R E L+
Sbjct: 551 HLVQHQR-VHTGEKPYE----------CIECGKAFSDGSYLVQHQRLHSGKRPYECLE-- 597
Query: 955 GYGHICGCCGQTYDDLGSLERHHQSQSSGTTADKAPSPLGVAGDAMEMVVDSVLEDIVNS 1014
CG+ + SL H + + + P V G A L +++
Sbjct: 598 --------CGKAFRQRASLICHQRCHTG-----EKPYECNVCGKAFSHRKSLTLHQRIHT 644
Query: 1015 VSGEGGDAKSQEGAGTPLGDSLCIQGGESLLEAQPRPFRCNQCGKTYRHGGSLVNHRKIH 1074
G+ + + + + RP+ C +CGK +R L +H++IH
Sbjct: 645 -----GEKPYECKECSKAFSQVAHLTLHKRIHTGERPYECKECGKAFRQSVHLAHHQRIH 699
Query: 1075 QTGD 1078
TG+
Sbjct: 700 -TGE 702
Score = 49.7 bits (117), Expect = 3e-05
Identities = 31/114 (27%), Positives = 47/114 (41%), Gaps = 25/114 (21%)
Query: 8 LSCSDCQRHFPSLPELSRHREL-------------------LHPSPNQDSEEADSIPRPY 48
L C+DC++ F + L+ H+ + H + +Q + +P+
Sbjct: 228 LKCNDCEKIFSKISTLTLHQRIHTGEKPYECIECGKAFSQSAHLAQHQRIHTGE---KPF 284
Query: 49 RCQQCGRGYRHPGSLVNHRRTHETGLFP--CTTCGKDFSNPMALKSHMRTHAPE 100
C +CG+ + LV H+R H TG P C C K FS L H R H E
Sbjct: 285 ECTECGKAFSQNAHLVQHQRVH-TGEKPYQCKQCNKAFSQLAHLAQHQRVHTGE 337
Score = 48.1 bits (113), Expect = 8e-05
Identities = 27/90 (30%), Positives = 42/90 (46%), Gaps = 15/90 (16%)
Query: 10 CSDCQRHFPSLPELSRHRELLHPSPNQDSEEADSIPRPYRCQQCGRGYRHPGSLVNHRRT 69
C++C + F L +H+ + + +PY+C+QC + + L H+R
Sbjct: 286 CTECGKAFSQNAHLVQHQRV------------HTGEKPYQCKQCNKAFSQLAHLAQHQRV 333
Query: 70 HETGLFP--CTTCGKDFSNPMALKSHMRTH 97
H TG P C CGK FS+ +L H R H
Sbjct: 334 H-TGEKPYECIECGKAFSDCSSLAHHRRIH 362
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,218,419
Number of Sequences: 37866
Number of extensions: 5429631
Number of successful extensions: 210891
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1062
Number of HSP's successfully gapped in prelim test: 188
Number of HSP's that attempted gapping in prelim test: 19518
Number of HSP's gapped (non-prelim): 48696
length of query: 1832
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1715
effective length of database: 13,817,196
effective search space: 23696491140
effective search space used: 23696491140
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.