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Search of human proteins with 21553331
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21553331 solute carrier family 2 (facilitated glucose
transporter), member 12 [Homo sapiens]
(617 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21553331 solute carrier family 2 (facilitated glucose transpo... 1204 0.0
gi|13540547 solute carrier family 2 member 10 [Homo sapiens] 348 6e-96
gi|203098995 solute carrier family 2 (facilitated glucose transp... 244 1e-64
gi|21361449 solute carrier family 2 (facilitated glucose transpo... 180 4e-45
gi|223029432 solute carrier family 2 (facilitated glucose transp... 148 2e-35
gi|4507011 glucose transporter 4 [Homo sapiens] 130 3e-30
gi|5902090 solute carrier family 2 (facilitated glucose transpor... 129 8e-30
gi|166795299 solute carrier family 2 (facilitated glucose transp... 125 1e-28
gi|23592238 glucose transporter 14 [Homo sapiens] 125 1e-28
gi|4557851 solute carrier family 2 (facilitated glucose transpor... 124 3e-28
gi|134053883 intestinal facilitative glucose transporter 7 [Homo... 121 2e-27
gi|4507013 solute carrier family 2 (facilitated glucose/fructose... 114 3e-25
gi|223029430 solute carrier family 2 (facilitated glucose transp... 91 3e-18
gi|47933387 solute carrier family 2, member 9 protein isoform 1 ... 91 4e-18
gi|47933389 solute carrier family 2, member 9 protein isoform 2 ... 89 1e-17
gi|190684655 glucose transporter protein 10 isoform a [Homo sapi... 87 5e-17
gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens] 87 5e-17
gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens] 87 5e-17
gi|213021148 SVOP-like isoform 1 [Homo sapiens] 64 5e-10
gi|24497499 solute carrier family 22 member 8 [Homo sapiens] 59 1e-08
gi|207447703 solute carrier family 2 (facilitated glucose/fructo... 59 1e-08
gi|4507005 solute carrier family 22 member 5 [Homo sapiens] 57 5e-08
gi|24308167 SV2 related protein [Homo sapiens] 57 5e-08
gi|23510410 solute carrier family 22 member 1 isoform b [Homo sa... 54 4e-07
gi|4506999 solute carrier family 22 member 1 isoform a [Homo sap... 54 4e-07
gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens] 53 7e-07
gi|24497490 solute carrier family 22 member 4 [Homo sapiens] 53 9e-07
gi|7662270 synaptic vesicle protein 2B homolog [Homo sapiens] 52 2e-06
gi|166197673 solute carrier family 22, member 15 [Homo sapiens] 52 2e-06
gi|216548223 synaptic vesicle glycoprotein 2 [Homo sapiens] 51 3e-06
>gi|21553331 solute carrier family 2 (facilitated glucose
transporter), member 12 [Homo sapiens]
Length = 617
Score = 1204 bits (3115), Expect = 0.0
Identities = 617/617 (100%), Positives = 617/617 (100%)
Query: 1 MVPVENTEGPSLLNQKGTAVETEGSGSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGI 60
MVPVENTEGPSLLNQKGTAVETEGSGSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGI
Sbjct: 1 MVPVENTEGPSLLNQKGTAVETEGSGSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGI 60
Query: 61 ISGALLQIKTLLALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLG 120
ISGALLQIKTLLALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLG
Sbjct: 61 ISGALLQIKTLLALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLG 120
Query: 121 SLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGIL 180
SLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGIL
Sbjct: 121 SLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGIL 180
Query: 181 SAYISNYAFANVFHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRL 240
SAYISNYAFANVFHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRL
Sbjct: 181 SAYISNYAFANVFHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRL 240
Query: 241 RALSDTTEELTVIKSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFY 300
RALSDTTEELTVIKSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFY
Sbjct: 241 RALSDTTEELTVIKSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFY 300
Query: 301 ASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVT 360
ASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVT
Sbjct: 301 ASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVT 360
Query: 361 MGIVNLNIHMNFTHICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLM 420
MGIVNLNIHMNFTHICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLM
Sbjct: 361 MGIVNLNIHMNFTHICRSHNSINQSLDESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLM 420
Query: 421 PLRNDVDKRGETTSASLLNAGLSHTEYQIVTDPGDVPAFLKWLSLASLLVYVAAFSIGLG 480
PLRNDVDKRGETTSASLLNAGLSHTEYQIVTDPGDVPAFLKWLSLASLLVYVAAFSIGLG
Sbjct: 421 PLRNDVDKRGETTSASLLNAGLSHTEYQIVTDPGDVPAFLKWLSLASLLVYVAAFSIGLG 480
Query: 481 PMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLPWVCFIYTIMSLA 540
PMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLPWVCFIYTIMSLA
Sbjct: 481 PMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGLPWVCFIYTIMSLA 540
Query: 541 SLLFVVMFIPETKGCSLEQISMELAKVNYVKNNICFMSHHQEELVPKQPQKRKPQEQLLE 600
SLLFVVMFIPETKGCSLEQISMELAKVNYVKNNICFMSHHQEELVPKQPQKRKPQEQLLE
Sbjct: 541 SLLFVVMFIPETKGCSLEQISMELAKVNYVKNNICFMSHHQEELVPKQPQKRKPQEQLLE 600
Query: 601 CNKLCGRGQSRQLSPET 617
CNKLCGRGQSRQLSPET
Sbjct: 601 CNKLCGRGQSRQLSPET 617
>gi|13540547 solute carrier family 2 member 10 [Homo sapiens]
Length = 541
Score = 348 bits (894), Expect = 6e-96
Identities = 214/547 (39%), Positives = 297/547 (54%), Gaps = 64/547 (11%)
Query: 42 LSSVTAAVSGLLVGYELGIISGALLQIKTLLALSCHEQEMVVSSLVIGALLASLTGGVLI 101
L + + + GL GYEL +ISGALL ++ LSC EQE +V SL++GALLASL GG LI
Sbjct: 10 LCASVSLLGGLTFGYELAVISGALLPLQLDFGLSCLEQEFLVGSLLLGALLASLVGGFLI 69
Query: 102 DRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQ 161
D YGR+ AI+ S+ +L GSL L L+ S L++GR +G +ISLSS+A C+Y++E+
Sbjct: 70 DCYGRKQAILGSNLVLLAGSLTLGLAGSLAWLVLGRAVVGFAISLSSMACCIYVSELVGP 129
Query: 162 HRRGLLVSLNELMIVIGILSAYISNYAFANVFHGWKYMFGLVIPLGVLQAIAMYFLPPSP 221
+RG+LVSL E I +GIL +Y NYA A GW++MFG VLQ++++ FLP
Sbjct: 130 RQRGVLVSLYEAGITVGILLSYALNYALAGTPWGWRHMFGWATAPAVLQSLSLLFLPAGT 189
Query: 222 RFLVMKGQ----EGAASKVLGRLRALSDTTEELTVIKSSLKDEYQYSFWDLFRSKDNMRT 277
+G + LG R +YSF DLFR++DNMR
Sbjct: 190 DETATHKDLIPLQGGEAPKLGPGRP-------------------RYSFLDLFRARDNMRG 230
Query: 278 RIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLL 337
R +GL LV F Q+TGQPN+L YAST+ SVGF +A LAS G+G VKV +T+ A L
Sbjct: 231 RTTVGLGLVLFQQLTGQPNVLCYASTIFSSVGFHGGSSAVLASVGLGAVKVAATLTAMGL 290
Query: 338 VDHVGSKTFLCIGSSVMAASLVTMGIVNLNIHMNFTHICRSHNSINQSLDESVIYGPGNL 397
VD G + L G ++MA S+ +G+V+ + M+ GP L
Sbjct: 291 VDRAGRRALLLAGCALMALSVSGIGLVSFAVPMDS--------------------GPSCL 330
Query: 398 STNNNTLRDHFKGISSHSRSSLMPLRNDVDKRGETTSASLLNAGLSHTEYQIVTDPGDVP 457
+ N T + G S + S +P + + E +L+ + DP P
Sbjct: 331 AVPNATGQTGLPGDSGLLQDSSLP---PIPRTNEDQREPILSTAKKTKPHPRSGDPSAPP 387
Query: 458 ------------------AFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRA 499
A L+W +L L+V+V+AFS G GP+ WLVLSEI+P IRGRA
Sbjct: 388 RLALSSALPGPPLPARGHALLRWTALLCLMVFVSAFSFGFGPVTWLVLSEIYPVEIRGRA 447
Query: 500 MALTSSMNWGINLLISLTFLTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQ 559
A +S NW NL ISL+FL + IGL W +Y + ++ L F+ +F+PETKG SL +
Sbjct: 448 FAFCNSFNWAANLFISLSFLDLIGTIGLSWTFLLYGLTAVLGLGFIYLFVPETKGQSLAE 507
Query: 560 ISMELAK 566
I + K
Sbjct: 508 IDQQFQK 514
>gi|203098995 solute carrier family 2 (facilitated glucose
transporter), member 13 [Homo sapiens]
Length = 648
Score = 244 bits (624), Expect = 1e-64
Identities = 165/536 (30%), Positives = 273/536 (50%), Gaps = 24/536 (4%)
Query: 39 FTFLSSVTAAVSGLLVGYELGIISGALLQIKTLLALSCHEQEMVVSSLVIGALLASLTGG 98
F ++ +V +A+ G L GY+ G++SGA+L +K L+L QE++VSS V A +++L GG
Sbjct: 80 FVYVVAVFSALGGFLFGYDTGVVSGAMLLLKRQLSLDALWQELLVSSTVGAAAVSALAGG 139
Query: 99 VLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIAEI 158
L +GRR AI+L+S L GS VL + + L+ GR+ +G+ I ++S+ VYIAE+
Sbjct: 140 ALNGVFGRRAAILLASALFTAGSAVLAAANNKETLLAGRLVVGLGIGIASMTVPVYIAEV 199
Query: 159 APQHRRGLLVSLNELMIVIGILSAYISNYAFANV-FHGWKYMFGLVIPLGVLQAIAMYFL 217
+P + RG LV++N L I G A + + AF+ + GW+YM GL V+Q FL
Sbjct: 200 SPPNLRGRLVTINTLFITGGQFFASVVDGAFSYLQKDGWRYMLGLAAVPAVIQFFGFLFL 259
Query: 218 PPSPRFLVMKGQEGAASKVLGRLRALSDTTEELTVIKSSLKDEYQY-----SFWDLFRSK 272
P SPR+L+ KGQ A ++L ++R EE IK+++++E + S
Sbjct: 260 PESPRWLIQKGQTQKARRILSQMRGNQTIDEEYDSIKNNIEEEEKEVGSAGPVICRMLSY 319
Query: 273 DNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVISTI 332
R +++G L F Q++G I++Y++T+L+ G + + A ++ I T+
Sbjct: 320 PPTRRALIVGCGLQMFQQLSGINTIMYYSATILQMSGVEDDRLAIWLASVTAFTNFIFTL 379
Query: 333 PATLLVDHVGSK--TFLCIGSSVMAASLVTMGIV---NLNIHMNFTHICRSHNSINQSLD 387
LV+ VG + TF + + +A ++ +G V ++ + F I S + +
Sbjct: 380 VGVWLVEKVGRRKLTFGSLAGTTVALIILALGFVLSAQVSPRITFKPIAPSGQNATCT-- 437
Query: 388 ESVIYGPGNLSTNNNTLRDHFKGISSHSRSSLMPLRNDVDKRGETTSASLLNAGLSHTEY 447
S N + D G S + + V +T+ + + T++
Sbjct: 438 --------RYSYCNECMLDPDCGFCYKMNKSTVIDSSCVPVNKASTNEAAWGRCENETKF 489
Query: 448 Q---IVTDPGDVPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTS 504
+ I P W +L L++Y+ F+ G+GPMPW V SEI+P R A +S
Sbjct: 490 KTEDIFWAYNFCPTPYSWTALLGLILYLVFFAPGMGPMPWTVNSEIYPLWARSTGNACSS 549
Query: 505 SMNWGINLLISLTFLTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQI 560
+NW N+L+SLTFL + + F+Y + LLF+ +PETKG LE+I
Sbjct: 550 GINWIFNVLVSLTFLHTAEYLTYYGAFFLYAGFAAVGLLFIYGCLPETKGKKLEEI 605
>gi|21361449 solute carrier family 2 (facilitated glucose
transporter), member 8 [Homo sapiens]
Length = 477
Score = 180 bits (456), Expect = 4e-45
Identities = 142/529 (26%), Positives = 242/529 (45%), Gaps = 84/529 (15%)
Query: 37 GMFTFLSSVTAAVSGLLVGYELGIISGALLQIKTLLALSCHEQEMVVS----SLVIGALL 92
G FL++ AA+ L G+ LG S A+ ++ + + S + +GA
Sbjct: 23 GRRVFLAAFAAALGPLSFGFALGYSSPAIPSLQRAAPPAPRLDDAAASWFGAVVTLGAAA 82
Query: 93 ASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAIGVSISLSSIATC 152
+ GG L+DR GR+ +++L S G V+ + +L+ GR+ G++ ++S+
Sbjct: 83 GGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDVWMLLGGRLLTGLACGVASLVAP 142
Query: 153 VYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAFANVFHGWKYMFGLVIPLGVLQAI 212
VYI+EIA RGLL S +LM+V+GIL AY++ + W + G V P L +
Sbjct: 143 VYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLE---WRWLAVLGCVPP--SLMLL 197
Query: 213 AMYFLPPSPRFLVMKGQEGAASKVLGRLRALSDTTEELTVIKSSLKDEYQYSFWDLFRSK 272
M F+P +PRFL+ + + A L L E+ + + SF +
Sbjct: 198 LMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPI-------GAEQSFHLALLRQ 250
Query: 273 DNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVISTI 332
+ +IG++L+ F Q++G ++FYA T+ + F+ +SLAS VGV++V+ T
Sbjct: 251 PGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKD---SSLASVVVGVIQVLFTA 307
Query: 333 PATLLVDHVGSKTFLCIGSSVMAASLVTMGIVNLNIHMNFTHICRSHNSINQSLDESVIY 392
A L++D G + L + VM S G ++ + Q
Sbjct: 308 VAALIMDRAGRRLLLVLSGVVMVFSTSAFG---------------AYFKLTQG------- 345
Query: 393 GPGNLSTNNNTLRDHFKGISSHSRSSLMPLRNDVDKRGETTSASLLNAGLSHTEYQIVTD 452
GPGN SSH S +
Sbjct: 346 GPGN---------------SSHVAISA----------------------------PVSAQ 362
Query: 453 PGDVPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINL 512
P D L WL++ S+ +++A F++G GP+PWL++SEIFP ++G A + NW +
Sbjct: 363 PVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAF 422
Query: 513 LISLTFLTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQIS 561
L++ F ++ +++ ++ + + S+LF + +PETKG +LEQI+
Sbjct: 423 LVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQIT 471
>gi|223029432 solute carrier family 2 (facilitated glucose
transporter), member 6 isoform 1 [Homo sapiens]
Length = 507
Score = 148 bits (373), Expect = 2e-35
Identities = 134/529 (25%), Positives = 227/529 (42%), Gaps = 82/529 (15%)
Query: 41 FLSSVTAAVSGLLVGYELGIISGALLQIKTLLALSCH----EQEMVVSSLVIGALLASLT 96
FL++ A + GY L S + ++ L H + S +GA L+
Sbjct: 39 FLATFAAVLGNFSFGYALVYTSPVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLS 98
Query: 97 GGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIA 156
+L D GR+ +I+ S+ G ++ + +L++GR G + L++ VY++
Sbjct: 99 AMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVS 158
Query: 157 EIAPQHRRGLLVSLNELMIVIGILSAYISNYAFANVFHGWKYMFGLVIPLGVLQAIAMYF 216
EIAP RG L + +LM V G LS Y + W+++ ++ + + F
Sbjct: 159 EIAPPGVRGALGATPQLMAVFGSLSLYA-----LGLLLPWRWLAVAGEAPVLIMILLLSF 213
Query: 217 LPPSPRFLVMKGQEGAASKVLGRLRALS-DTTEELTVIKSSLKDEYQYSFWDLFRSKDNM 275
+P SPRFL+ +G++ A + L LR D E I+ +++ + W R+
Sbjct: 214 MPNSPRFLLSRGRDEEALRALAWLRGTDVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVC 273
Query: 276 RTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGF---QSNEAASLASTGVGVVKVISTI 332
R I + L + Q+TG IL Y ++ S ++AA VG V+++S +
Sbjct: 274 RP-ITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDDAAI-----VGAVRLLSVL 327
Query: 333 PATLLVDHVGSKTFLCIGSSVMAASLVTMGIVNLNIHMNFTHICRSHNSINQSLDESVIY 392
A L +D G K L + +++M A+ +T+G L IH +
Sbjct: 328 IAALTMDLAGRKVLLFVSAAIMFAANLTLG---LYIH----------------------F 362
Query: 393 GPGNLSTNNNTLRDHFKGISSHSRSSLMPLRNDVDKRGETTSASLLNAGLSHTEYQIVTD 452
GP LS N+ AGL + +
Sbjct: 363 GPRPLSPNS-------------------------------------TAGLESESWGDLAQ 385
Query: 453 PGDVPA-FLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGIN 511
P PA +L + L + ++++ +++G GP+ WL++SE+ P RG A L +W
Sbjct: 386 PLAAPAGYLTLVPLLATMLFIMGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTA 445
Query: 512 LLISLTFLTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQI 560
+++ +FL V GL F + + L SL+F +PETKG SLEQI
Sbjct: 446 FVLTKSFLPVVSTFGLQVPFFFFAAICLVSLVFTGCCVPETKGRSLEQI 494
>gi|4507011 glucose transporter 4 [Homo sapiens]
Length = 509
Score = 130 bits (328), Expect = 3e-30
Identities = 108/376 (28%), Positives = 178/376 (47%), Gaps = 45/376 (11%)
Query: 24 GSGSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGIISGALLQIK-------------- 69
GS PP R G L+ +A + L GY +G+I+ I+
Sbjct: 9 GSEDGEPPQQRVTGTLV-LAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPE 67
Query: 70 -----------TLLALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLG 118
TL ALS V+ +G +++S G++ GR+ A+++++ L
Sbjct: 68 GPSSIPPGTLTTLWALS-------VAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAV 120
Query: 119 LGSLVLILS---LSYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMI 175
LG ++ L+ SY +LI+GR IG L+S +Y+ EIAP H RG L +LN+L I
Sbjct: 121 LGGSLMGLANAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAI 180
Query: 176 VIGILSAYISNY-AFANVFHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFL-VMKGQEGAA 233
VIGIL A + + W + GL + +LQ + + F P SPR+L +++ EG A
Sbjct: 181 VIGILIAQVLGLESLLGTASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPA 240
Query: 234 SKVLGRLRALSDTT---EELTVIKSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQ 290
K L RL +D + EL K L+ E S L S+ + R ++I + L Q
Sbjct: 241 RKSLKRLTGWADVSGVLAELKDEKRKLERERPLSLLQLLGSRTH-RQPLIIAVVLQLSQQ 299
Query: 291 ITGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIG 350
++G + +Y++++ ++ G + A+ G GVV + T+ + LLV+ G +T +G
Sbjct: 300 LSGINAVFYYSTSIFETAGVGQ---PAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLG 356
Query: 351 SSVMAASLVTMGIVNL 366
+ M + M + L
Sbjct: 357 LAGMCGCAILMTVALL 372
Score = 79.3 bits (194), Expect = 9e-15
Identities = 38/106 (35%), Positives = 66/106 (62%), Gaps = 2/106 (1%)
Query: 456 VPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLIS 515
VPA + ++S+ ++ +VA F IG GP+PW +++E+F G R AMA+ NW N +I
Sbjct: 377 VPA-MSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFSNWTSNFIIG 435
Query: 516 LTFLTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQIS 561
+ F V + +G P+V ++ ++ L +F + +PET+G + +QIS
Sbjct: 436 MGFQYVAEAMG-PYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQIS 480
>gi|5902090 solute carrier family 2 (facilitated glucose
transporter), member 3 [Homo sapiens]
Length = 496
Score = 129 bits (324), Expect = 8e-30
Identities = 99/354 (27%), Positives = 179/354 (50%), Gaps = 28/354 (7%)
Query: 47 AAVSGLLVGYELGIISGALLQIKTLLALSCHEQ------EMVVSSL--------VIGALL 92
A + GY G+I+ IK + + ++ E++++SL +G ++
Sbjct: 17 ATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVLLTSLWSLSVAIFSVGGMI 76
Query: 93 ASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLIL---SLSYTVLIVGRIAIGVSISLSSI 149
S + G+ ++R+GRR ++++ + L G + L + S +LI+GR+ IG+ L +
Sbjct: 77 GSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTG 136
Query: 150 ATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAF-ANVFHGWKYMFGLVIPLGV 208
+YI EI+P RG +LN+L IV+GIL A I F W + G I +
Sbjct: 137 FVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAI 196
Query: 209 LQAIAMYFLPPSPRFLVM-KGQEGAASKVLGRLRALSDTTEELTVIK---SSLKDEYQYS 264
LQ+ A+ F P SPRFL++ + +E A ++L RL D ++++ +K + + E Q +
Sbjct: 197 LQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQDIQEMKDESARMSQEKQVT 256
Query: 265 FWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNEAASLASTGVG 324
+LFR + R I+I + L Q++G + +Y++ + K G Q A+ G G
Sbjct: 257 VLELFR-VSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQE---PIYATIGAG 312
Query: 325 VVKVISTIPATLLVDHVGSKTFLCIGSSVMA--ASLVTMGIVNLNIHMNFTHIC 376
VV I T+ + LV+ G +T IG MA ++L+T+ ++ + + + +C
Sbjct: 313 VVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDNYNGMSFVC 366
Score = 73.6 bits (179), Expect = 5e-13
Identities = 36/102 (35%), Positives = 59/102 (57%), Gaps = 1/102 (0%)
Query: 460 LKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFL 519
+ ++ + ++LV+VA F IG GP+PW +++E+F G R AMA+ NW N L+ L F
Sbjct: 362 MSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFP 421
Query: 520 TVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQIS 561
+ +G +V I+T + L F +PET+G + E I+
Sbjct: 422 SAAHYLG-AYVFIIFTGFLITFLAFTFFKVPETRGRTFEDIT 462
>gi|166795299 solute carrier family 2 (facilitated glucose
transporter), member 1 [Homo sapiens]
Length = 492
Score = 125 bits (314), Expect = 1e-28
Identities = 86/292 (29%), Positives = 156/292 (53%), Gaps = 18/292 (6%)
Query: 83 VSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLI----LSLSYTVLIVGRI 138
V+ +G ++ S + G+ ++R+GRR ++++ + LL S VL+ L S+ +LI+GR
Sbjct: 69 VAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMN-LLAFVSAVLMGFSKLGKSFEMLILGRF 127
Query: 139 AIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAFANVFHG--- 195
IGV L++ +Y+ E++P RG L +L++L IV+GIL A + + ++
Sbjct: 128 IIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQV--FGLDSIMGNKDL 185
Query: 196 WKYMFGLVIPLGVLQAIAMYFLPPSPRFLVM-KGQEGAASKVLGRLRALSDTTEELTVIK 254
W + ++ +LQ I + F P SPRFL++ + +E A VL +LR +D T +L +K
Sbjct: 186 WPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHDLQEMK 245
Query: 255 SSLKD---EYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQ 311
+ E + + +LFRS R I+I + L Q++G + +Y++++ + G Q
Sbjct: 246 EESRQMMREKKVTILELFRS-PAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQ 304
Query: 312 SNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGI 363
A++ G G+V T+ + +V+ G +T IG + MA + M I
Sbjct: 305 QPVYATI---GSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTI 353
Score = 77.0 bits (188), Expect = 5e-14
Identities = 34/103 (33%), Positives = 63/103 (61%), Gaps = 1/103 (0%)
Query: 459 FLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTF 518
++ +LS+ ++ +VA F +G GP+PW +++E+F G R A+A+ NW N ++ + F
Sbjct: 363 WMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCF 422
Query: 519 LTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQIS 561
V L G P+V I+T++ + +F +PETKG + ++I+
Sbjct: 423 QYVEQLCG-PYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIA 464
>gi|23592238 glucose transporter 14 [Homo sapiens]
Length = 520
Score = 125 bits (313), Expect = 1e-28
Identities = 96/354 (27%), Positives = 177/354 (50%), Gaps = 28/354 (7%)
Query: 47 AAVSGLLVGYELGIISGALLQIKTLLALSCHEQ--------------EMVVSSLVIGALL 92
A + GY G+I+ IK + + ++ + V+ +G ++
Sbjct: 41 ATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAIFSVGGMI 100
Query: 93 ASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLIL---SLSYTVLIVGRIAIGVSISLSSI 149
S + G+ ++R+GRR ++++ + L G ++ L + S +LI+GR+ IG+ L +
Sbjct: 101 GSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTG 160
Query: 150 ATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNY-AFANVFHGWKYMFGLVIPLGV 208
+YI EI+P RG +LN+L IVIGIL A I W + G I +
Sbjct: 161 FVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAI 220
Query: 209 LQAIAMYFLPPSPRFLVM-KGQEGAASKVLGRLRALSDTTEELTVIK---SSLKDEYQYS 264
LQ+ A+ P SPRFL++ + +E A+++L RL D ++++ +K + + E Q +
Sbjct: 221 LQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDVSQDIQEMKDESARMSQEKQVT 280
Query: 265 FWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNEAASLASTGVG 324
+LFR + R I+I + L Q++G + +Y++ + K G Q A++++ G
Sbjct: 281 VLELFR-VSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISA---G 336
Query: 325 VVKVISTIPATLLVDHVGSKTFLCIGSSVMA--ASLVTMGIVNLNIHMNFTHIC 376
VV I T+ + LV+ G +T IG MA ++L+T+ ++ N + + +C
Sbjct: 337 VVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVC 390
Score = 73.6 bits (179), Expect = 5e-13
Identities = 36/102 (35%), Positives = 59/102 (57%), Gaps = 1/102 (0%)
Query: 460 LKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFL 519
+ ++ + ++LV+VA F IG GP+PW +++E+F G R AMA+ NW N L+ L F
Sbjct: 386 MSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFP 445
Query: 520 TVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQIS 561
+ +G +V I+T + L F +PET+G + E I+
Sbjct: 446 SAAYYLG-AYVFIIFTGFLITFLAFTFFKVPETRGRTFEDIT 486
>gi|4557851 solute carrier family 2 (facilitated glucose
transporter), member 2 [Homo sapiens]
Length = 524
Score = 124 bits (310), Expect = 3e-28
Identities = 92/295 (31%), Positives = 155/295 (52%), Gaps = 14/295 (4%)
Query: 83 VSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSL---SYTVLIVGRIA 139
VSS +G + AS GG L D GR A+++++ L +G+L++ S S+ ++I GR
Sbjct: 101 VSSFAVGGMTASFFGGWLGDTLGRIKAMLVANILSLVGALLMGFSKLGPSHILIIAGRSI 160
Query: 140 IGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAF-ANVFHGWKY 198
G+ L S +YI EIAP RG L + ++L IV GIL + I F + W
Sbjct: 161 SGLYCGLISGLVPMYIGEIAPTALRGALGTFHQLAIVTGILISQIIGLEFILGNYDLWHI 220
Query: 199 MFGLVIPLGVLQAIAMYFLPPSPRFLVMK-GQEGAASKVLGRLRALSDTTEELTVIKSSL 257
+ GL +LQ++ ++F P SPR+L +K +E A + L RLR D T+++ ++
Sbjct: 221 LLGLSGVRAILQSLLLFFCPESPRYLYIKLDEEVKAKQSLKRLRGYDDVTKDINEMRKER 280
Query: 258 KD---EYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNE 314
++ E + S LF + + R I++ L L Q +G I +Y++++ ++ G
Sbjct: 281 EEASSEQKVSIIQLF-TNSSYRQPILVALMLHVAQQFSGINGIFYYSTSIFQTAGISKPV 339
Query: 315 AASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVM--AASLVTMGIVNLN 367
A++ GVG V ++ T + LV+ G ++ IG S M A +++G+V LN
Sbjct: 340 YATI---GVGAVNMVFTAVSVFLVEKAGRRSLFLIGMSGMFVCAIFMSVGLVLLN 391
Score = 84.0 bits (206), Expect = 4e-16
Identities = 39/109 (35%), Positives = 68/109 (62%), Gaps = 1/109 (0%)
Query: 458 AFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLT 517
+++ ++S+ ++ ++V+ F IG GP+PW +++E F G R A+A+ + NW N +++L
Sbjct: 394 SWMSYVSMIAIFLFVSFFEIGPGPIPWFMVAEFFSQGPRPAALAIAAFSNWTCNFIVALC 453
Query: 518 FLTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQISMELAK 566
F + D G P+V F++ + LA LF +PETKG S E+I+ E K
Sbjct: 454 FQYIADFCG-PYVFFLFAGVLLAFTLFTFFKVPETKGKSFEEIAAEFQK 501
>gi|134053883 intestinal facilitative glucose transporter 7 [Homo
sapiens]
Length = 512
Score = 121 bits (303), Expect = 2e-27
Identities = 80/303 (26%), Positives = 159/303 (52%), Gaps = 13/303 (4%)
Query: 71 LLALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSL-- 128
LL SC VS +G LL SL G+L+D GR+ +++++ + ++++ +S
Sbjct: 74 LLLWSC-----TVSMFPLGGLLGSLLVGLLVDSCGRKGTLLINNIFAIIPAILMGVSKVA 128
Query: 129 -SYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYI-SN 186
++ +++ R+ +GV +S A +Y+ E+AP++ RG++ ++ E+ +++G+ A I S
Sbjct: 129 KAFELIVFSRVVLGVCAGISYSALPMYLGELAPKNLRGMVGTMTEVFVIVGVFLAQIFSL 188
Query: 187 YAFANVFHGWKYMFGLVIPLGVLQAIAMYFLPPSPRF-LVMKGQEGAASKVLGRLRALSD 245
A GW + L +LQ + + F P SPR+ L+ KG E A + L RLR +D
Sbjct: 189 QAILGNPAGWPVLLALTGVPALLQLLTLPFFPESPRYSLIQKGDEATARQALRRLRGHTD 248
Query: 246 TTEELTVIKSSLKDEYQYSFWDLFR--SKDNMRTRIMIGLTLVFFVQITGQPNILFYAST 303
EL +++ + E + + ++R +++ + L+ Q++G I +YA T
Sbjct: 249 MEAELEDMRAEARAERAEGHLSVLHLCALRSLRWQLLSIIVLMAGQQLSGINAINYYADT 308
Query: 304 VLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGI 363
+ S G ++ + + G GVV ++ TI + +LV+ +G + L G + ++ + + +
Sbjct: 309 IYTSAGVEAAH-SQYVTVGSGVVNIVMTITSAVLVERLGRRHLLLAGYGICGSACLVLTV 367
Query: 364 VNL 366
V L
Sbjct: 368 VLL 370
Score = 64.7 bits (156), Expect = 2e-10
Identities = 39/138 (28%), Positives = 70/138 (50%), Gaps = 6/138 (4%)
Query: 460 LKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFL 519
L +L + + Y+A SIG P+P +V +EIF R A + +++W N +I F
Sbjct: 378 LSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFMVDGAVHWLTNFIIGFLFP 437
Query: 520 TVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQISMELAKVNYVKNNICFMSH 579
++ + IG + I+ + L + +++ + IPETKG + +I+ AK N VK +
Sbjct: 438 SIQEAIG-AYSFIIFAGICLLTAIYIYVVIPETKGKTFVEINRIFAKRNRVK-----LPE 491
Query: 580 HQEELVPKQPQKRKPQEQ 597
+EE + P P ++
Sbjct: 492 EKEETIDAGPPTASPAKE 509
Score = 32.3 bits (72), Expect = 1.3
Identities = 37/159 (23%), Positives = 68/159 (42%), Gaps = 16/159 (10%)
Query: 75 SCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVL---------I 125
+ H Q + V S V+ ++ ++T VL++R GRR ++ + G LVL +
Sbjct: 317 AAHSQYVTVGSGVVNIVM-TITSAVLVERLGRRHLLLAGYGICGSACLVLTVVLLFQNRV 375
Query: 126 LSLSYT-VLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYI 184
LSY ++ V G SI S + + V RR + + + L+ +I
Sbjct: 376 PELSYLGIICVFAYIAGHSIGPSPVPSVVRTEIFLQSSRRAAFM----VDGAVHWLTNFI 431
Query: 185 SNYAFANVFHG-WKYMFGLVIPLGVLQAIAMYFLPPSPR 222
+ F ++ Y F + + +L AI +Y + P +
Sbjct: 432 IGFLFPSIQEAIGAYSFIIFAGICLLTAIYIYVVIPETK 470
>gi|4507013 solute carrier family 2 (facilitated glucose/fructose
transporter), member 5 isoform 1 [Homo sapiens]
Length = 501
Score = 114 bits (285), Expect = 3e-25
Identities = 82/282 (29%), Positives = 142/282 (50%), Gaps = 12/282 (4%)
Query: 81 MVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILS---LSYTVLIVGR 137
+ VS G + SL G L++++GR+ A++ ++ + ++++ S S+ ++I+ R
Sbjct: 73 VTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISR 132
Query: 138 IAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNY--AFANVFHG 195
+ +G+ +SS +Y+ E+AP++ RG L + +L I +GIL A I ANV G
Sbjct: 133 LLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQIFGLRNLLANV-DG 191
Query: 196 WKYMFGLVIPLGVLQAIAMYFLPPSPRF-LVMKGQEGAASKVLGRLRALSDTTEELTVIK 254
W + GL LQ + + F P SPR+ L+ K E AA K L LR E+ I+
Sbjct: 192 WPILLGLTGVPAALQLLLLPFFPESPRYLLIQKKDEAAAKKALQTLRGWDSVDREVAEIR 251
Query: 255 SSLKDEYQYSF---WDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQ 311
+ E F LFR + ++R +++ + L+ Q++G I +YA + S G
Sbjct: 252 QEDEAEKAAGFISVLKLFRMR-SLRWQLLSIIVLMGGQQLSGVNAIYYYADQIYLSAGV- 309
Query: 312 SNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSV 353
E + G G V V+ T A +V+ +G + L +G S+
Sbjct: 310 PEEHVQYVTAGTGAVNVVMTFCAVFVVELLGRRLLLLLGFSI 351
Score = 61.2 bits (147), Expect = 3e-09
Identities = 29/116 (25%), Positives = 65/116 (56%), Gaps = 1/116 (0%)
Query: 455 DVPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLI 514
D +++ ++S+ ++ YV ++G P+P L+++EIF R A + S++W N +
Sbjct: 367 DTVSWMPYISIVCVISYVIGHALGPSPIPALLITEIFLQSSRPSAFMVGGSVHWLSNFTV 426
Query: 515 SLTFLTVTDLIGLPWVCFIYTIMSLASLLFVVMFIPETKGCSLEQISMELAKVNYV 570
L F + + +G P+ ++ ++ L + +++ + +PETK + +I+ K+N V
Sbjct: 427 GLIFPFIQEGLG-PYSFIVFAVICLLTTIYIFLIVPETKAKTFIEINQIFTKMNKV 481
>gi|223029430 solute carrier family 2 (facilitated glucose
transporter), member 6 isoform 2 [Homo sapiens]
Length = 445
Score = 90.9 bits (224), Expect = 3e-18
Identities = 82/328 (25%), Positives = 144/328 (43%), Gaps = 19/328 (5%)
Query: 41 FLSSVTAAVSGLLVGYELGIISGALLQIKTLLALSCH----EQEMVVSSLVIGALLASLT 96
FL++ A + GY L S + ++ L H + S +GA L+
Sbjct: 39 FLATFAAVLGNFSFGYALVYTSPVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLS 98
Query: 97 GGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIA 156
+L D GR+ +I+ S+ G ++ + +L++GR G + L++ VY++
Sbjct: 99 AMILNDLLGRKLSIMFSAVPSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVS 158
Query: 157 EIAPQHRRGLLVSLNELMIVIGILSAYISNYAFANVFHGWKYMFGLVIPLGVLQAIAMYF 216
EIAP RG L + +LM V G LS Y + W+++ ++ + + F
Sbjct: 159 EIAPPGVRGALGATPQLMAVFGSLSLYA-----LGLLLPWRWLAVAGEAPVLIMILLLSF 213
Query: 217 LPPSPRFLVMKGQEGAASKVLGRLRALS-DTTEELTVIKSSLKDEYQYSFWDLFRSKDNM 275
+P SPRFL+ +G++ A + L LR D E I+ +++ + W R+
Sbjct: 214 MPNSPRFLLSRGRDEEALRALAWLRGTDVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVC 273
Query: 276 RTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGF---QSNEAASLASTGVGVVKVISTI 332
R I + L + Q+TG IL Y ++ S ++AA VG V+++S +
Sbjct: 274 RP-ITVALLMRLLQQLTGITPILVYLQSIFDSTAVLLPPKDDAAI-----VGAVRLLSVL 327
Query: 333 PATLLVDHVGSKTFLCIGSSVMAASLVT 360
A L +D G K L + + +T
Sbjct: 328 IAALTMDLAGRKVLLFVSGYAVGWGPIT 355
Score = 70.1 bits (170), Expect = 6e-12
Identities = 35/93 (37%), Positives = 55/93 (59%)
Query: 468 LLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTVTDLIGL 527
+L++V+ +++G GP+ WL++SE+ P RG A L +W +++ +FL V GL
Sbjct: 340 VLLFVSGYAVGWGPITWLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSFLPVVSTFGL 399
Query: 528 PWVCFIYTIMSLASLLFVVMFIPETKGCSLEQI 560
F + + L SL+F +PETKG SLEQI
Sbjct: 400 QVPFFFFAAICLVSLVFTGCCVPETKGRSLEQI 432
>gi|47933387 solute carrier family 2, member 9 protein isoform 1
[Homo sapiens]
Length = 540
Score = 90.5 bits (223), Expect = 4e-18
Identities = 79/360 (21%), Positives = 161/360 (44%), Gaps = 27/360 (7%)
Query: 26 GSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGIISGALLQIKTLLALSCHEQE----- 80
G R W+ C + S A S L GY L +++ IK S +
Sbjct: 46 GRRRKDWS--CSLLV-ASLAGAFGSSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPID 102
Query: 81 ---------MVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSL--- 128
+ VS IG L+ +L ++ GR+ ++ ++ +L++ SL
Sbjct: 103 PDTLTLLWSVTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAG 162
Query: 129 SYTVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYA 188
++ +LIVGR +G+ ++ +Y++EI+P+ RG L + + I IG+ + +
Sbjct: 163 AFEMLIVGRFIMGIDGGVALSVLPMYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLP 222
Query: 189 -FANVFHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVM-KGQEGAASKVLGRLRALSDT 246
W Y+FG+++ V+Q +++ FLP SPR+L++ K E A K +D
Sbjct: 223 ELLGKESTWPYLFGVIVVPAVVQLLSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADV 282
Query: 247 TEELTVIKSSLKDEYQ---YSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYAST 303
++E+ + + + + S +L R+ +R +++ + + Q+ G I FY ++
Sbjct: 283 SQEVEEVLAESRVQRSIRLVSVLELLRA-PYVRWQVVTVIVTMACYQLCGLNAIWFYTNS 341
Query: 304 VLKSVGFQSNEAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGI 363
+ G + + G ++ ++ + + L+++H+G + L G +M T+ I
Sbjct: 342 IFGKAGIPPAK-IPYVTLSTGGIETLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTI 400
Score = 52.4 bits (124), Expect = 1e-06
Identities = 29/115 (25%), Positives = 56/115 (48%), Gaps = 3/115 (2%)
Query: 455 DVPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLI 514
D ++ +LS+ +L +A+F G G +P+++ E F R A + ++NW N +
Sbjct: 406 DHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAV 465
Query: 515 SLTFLTVTDLIGLPWVCF-IYTIMSLASLLFVVMFIPETKGCSLEQISMELAKVN 568
L F + L CF ++ + + +++ +PETK + +IS +K N
Sbjct: 466 GLLFPFIQK--SLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRN 518
>gi|47933389 solute carrier family 2, member 9 protein isoform 2
[Homo sapiens]
Length = 511
Score = 89.0 bits (219), Expect = 1e-17
Identities = 73/336 (21%), Positives = 153/336 (45%), Gaps = 24/336 (7%)
Query: 50 SGLLVGYELGIISGALLQIKTLLALSCHEQE--------------MVVSSLVIGALLASL 95
S L GY L +++ IK S + + VS IG L+ +L
Sbjct: 38 SSFLYGYNLSVVNAPTPYIKAFYNESWERRHGRPIDPDTLTLLWSVTVSIFAIGGLVGTL 97
Query: 96 TGGVLIDRYGRRTAIILSSCLLGLGSLVLILSL---SYTVLIVGRIAIGVSISLSSIATC 152
++ GR+ ++ ++ +L++ SL ++ +LIVGR +G+ ++
Sbjct: 98 IVKMIGKVLGRKHTLLANNGFAISAALLMACSLQAGAFEMLIVGRFIMGIDGGVALSVLP 157
Query: 153 VYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYA-FANVFHGWKYMFGLVIPLGVLQA 211
+Y++EI+P+ RG L + + I IG+ + + W Y+FG+++ V+Q
Sbjct: 158 MYLSEISPKEIRGSLGQVTAIFICIGVFTGQLLGLPELLGKESTWPYLFGVIVVPAVVQL 217
Query: 212 IAMYFLPPSPRFLVM-KGQEGAASKVLGRLRALSDTTEELTVIKSSLKDEYQ---YSFWD 267
+++ FLP SPR+L++ K E A K +D ++E+ + + + + S +
Sbjct: 218 LSLPFLPDSPRYLLLEKHNEARAVKAFQTFLGKADVSQEVEEVLAESRVQRSIRLVSVLE 277
Query: 268 LFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNEAASLASTGVGVVK 327
L R+ +R +++ + + Q+ G I FY +++ G + + G ++
Sbjct: 278 LLRA-PYVRWQVVTVIVTMACYQLCGLNAIWFYTNSIFGKAGIPPAK-IPYVTLSTGGIE 335
Query: 328 VISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGI 363
++ + + L+++H+G + L G +M T+ I
Sbjct: 336 TLAAVFSGLVIEHLGRRPLLIGGFGLMGLFFGTLTI 371
Score = 52.4 bits (124), Expect = 1e-06
Identities = 29/115 (25%), Positives = 56/115 (48%), Gaps = 3/115 (2%)
Query: 455 DVPAFLKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLI 514
D ++ +LS+ +L +A+F G G +P+++ E F R A + ++NW N +
Sbjct: 377 DHAPWVPYLSIVGILAIIASFCSGPGGIPFILTGEFFQQSQRPAAFIIAGTVNWLSNFAV 436
Query: 515 SLTFLTVTDLIGLPWVCF-IYTIMSLASLLFVVMFIPETKGCSLEQISMELAKVN 568
L F + L CF ++ + + +++ +PETK + +IS +K N
Sbjct: 437 GLLFPFIQK--SLDTYCFLVFATICITGAIYLYFVLPETKNRTYAEISQAFSKRN 489
>gi|190684655 glucose transporter protein 10 isoform a [Homo
sapiens]
Length = 503
Score = 87.0 bits (214), Expect = 5e-17
Identities = 75/341 (21%), Positives = 152/341 (44%), Gaps = 25/341 (7%)
Query: 37 GMFTFLSSVTAAVSGLL-VGYELGIISGALLQIKTLLALSCHEQ--------------EM 81
G L+ A + G GY L II+ L I+ + + +
Sbjct: 17 GRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSL 76
Query: 82 VVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSL---SYTVLIVGRI 138
+VS +G L +L G L GR+ ++++++ + +++ S S+ ++++GR+
Sbjct: 77 IVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRL 136
Query: 139 AIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNY-AFANVFHGWK 197
+GV+ +S +Y+ E AP+ RG + + + +GI+ + W
Sbjct: 137 LVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWP 196
Query: 198 YMFGLVIPLGVLQAIAMYFLPPSPRFLVMK-GQEGAASKVLGRLRALSDTT---EELTVI 253
+ + G LQ ++ LP SPR+L++ G A L RLR D EEL
Sbjct: 197 LLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEE 256
Query: 254 KSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSN 313
+++ + W+LF+ + +R ++ + L +++ G ++ YAS+V + G
Sbjct: 257 RAACQGCRARRPWELFQHR-ALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEA 315
Query: 314 EAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVM 354
+ A G G ++++ + + ++++ VG + L G S+M
Sbjct: 316 K-IQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLM 355
Score = 48.1 bits (113), Expect = 2e-05
Identities = 26/111 (23%), Positives = 60/111 (54%), Gaps = 7/111 (6%)
Query: 462 WLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTV 521
+L++A + ++ +F IG + ++ +E+F R A + ++ W + +L+ L F +
Sbjct: 377 YLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFI 436
Query: 522 TDLIGLPWVCFIYTI---MSLASLLFVVMFIPETKGCSLEQISMELAKVNY 569
+ + F+Y + + ++ +F+PETKG + ++IS EL ++N+
Sbjct: 437 MEALSH----FLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNF 483
>gi|68226420 glucose transporter protein 10 isoform c [Homo sapiens]
Length = 496
Score = 87.0 bits (214), Expect = 5e-17
Identities = 75/341 (21%), Positives = 152/341 (44%), Gaps = 25/341 (7%)
Query: 37 GMFTFLSSVTAAVSGLL-VGYELGIISGALLQIKTLLALSCHEQ--------------EM 81
G L+ A + G GY L II+ L I+ + + +
Sbjct: 10 GRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSL 69
Query: 82 VVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSL---SYTVLIVGRI 138
+VS +G L +L G L GR+ ++++++ + +++ S S+ ++++GR+
Sbjct: 70 IVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRL 129
Query: 139 AIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNY-AFANVFHGWK 197
+GV+ +S +Y+ E AP+ RG + + + +GI+ + W
Sbjct: 130 LVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWP 189
Query: 198 YMFGLVIPLGVLQAIAMYFLPPSPRFLVMK-GQEGAASKVLGRLRALSDTT---EELTVI 253
+ + G LQ ++ LP SPR+L++ G A L RLR D EEL
Sbjct: 190 LLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEE 249
Query: 254 KSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSN 313
+++ + W+LF+ + +R ++ + L +++ G ++ YAS+V + G
Sbjct: 250 RAACQGCRARRPWELFQHR-ALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEA 308
Query: 314 EAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVM 354
+ A G G ++++ + + ++++ VG + L G S+M
Sbjct: 309 K-IQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLM 348
Score = 48.1 bits (113), Expect = 2e-05
Identities = 26/111 (23%), Positives = 60/111 (54%), Gaps = 7/111 (6%)
Query: 462 WLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTV 521
+L++A + ++ +F IG + ++ +E+F R A + ++ W + +L+ L F +
Sbjct: 370 YLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFI 429
Query: 522 TDLIGLPWVCFIYTI---MSLASLLFVVMFIPETKGCSLEQISMELAKVNY 569
+ + F+Y + + ++ +F+PETKG + ++IS EL ++N+
Sbjct: 430 MEALSH----FLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNF 476
>gi|68226418 glucose transporter protein 10 isoform b [Homo sapiens]
Length = 499
Score = 87.0 bits (214), Expect = 5e-17
Identities = 75/341 (21%), Positives = 152/341 (44%), Gaps = 25/341 (7%)
Query: 37 GMFTFLSSVTAAVSGLL-VGYELGIISGALLQIKTLLALSCHEQ--------------EM 81
G L+ A + G GY L II+ L I+ + + +
Sbjct: 13 GRILLLTICAAGIGGTFQFGYNLSIINAPTLHIQEFTNETWQARTGEPLPDHLVLLMWSL 72
Query: 82 VVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSL---SYTVLIVGRI 138
+VS +G L +L G L GR+ ++++++ + +++ S S+ ++++GR+
Sbjct: 73 IVSLYPLGGLFGALLAGPLAITLGRKKSLLVNNIFVVSAAILFGFSRKAGSFEMIMLGRL 132
Query: 139 AIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNY-AFANVFHGWK 197
+GV+ +S +Y+ E AP+ RG + + + +GI+ + W
Sbjct: 133 LVGVNAGVSMNIQPMYLGESAPKELRGAVAMSSAIFTALGIVMGQVVGLRELLGGPQAWP 192
Query: 198 YMFGLVIPLGVLQAIAMYFLPPSPRFLVMK-GQEGAASKVLGRLRALSDTT---EELTVI 253
+ + G LQ ++ LP SPR+L++ G A L RLR D EEL
Sbjct: 193 LLLASCLVPGALQLASLPLLPESPRYLLIDCGDTEACLAALRRLRGSGDLAGELEELEEE 252
Query: 254 KSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSN 313
+++ + W+LF+ + +R ++ + L +++ G ++ YAS+V + G
Sbjct: 253 RAACQGCRARRPWELFQHR-ALRRQVTSLVVLGSAMELCGNDSVYAYASSVFRKAGVPEA 311
Query: 314 EAASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVM 354
+ A G G ++++ + + ++++ VG + L G S+M
Sbjct: 312 K-IQYAIIGTGSCELLTAVVSCVVIERVGRRVLLIGGYSLM 351
Score = 48.1 bits (113), Expect = 2e-05
Identities = 26/111 (23%), Positives = 60/111 (54%), Gaps = 7/111 (6%)
Query: 462 WLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGINLLISLTFLTV 521
+L++A + ++ +F IG + ++ +E+F R A + ++ W + +L+ L F +
Sbjct: 373 YLAMACIFAFILSFGIGPAGVTGILATELFDQMARPAACMVCGALMWIMLILVGLGFPFI 432
Query: 522 TDLIGLPWVCFIYTI---MSLASLLFVVMFIPETKGCSLEQISMELAKVNY 569
+ + F+Y + + ++ +F+PETKG + ++IS EL ++N+
Sbjct: 433 MEALSH----FLYVPFLGVCVCGAIYTGLFLPETKGKTFQEISKELHRLNF 479
>gi|213021148 SVOP-like isoform 1 [Homo sapiens]
Length = 492
Score = 63.5 bits (153), Expect = 5e-10
Identities = 70/292 (23%), Positives = 128/292 (43%), Gaps = 34/292 (11%)
Query: 19 AVETEGSGSRHPPWARGCGMFTFLSSVTAAVSGLLVGYELGIISGALLQIKTLLALSCHE 78
AVET G G H +F + S +G++ E+ +I+ I+ L +
Sbjct: 37 AVETIGFGRFH------IALFLIMGS-----TGVVEAMEIMLIAVVSPVIRCEWQLENWQ 85
Query: 79 QEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRI 138
+V + + G ++ S+ G+L DRYGR +++S SL+ + SY + R
Sbjct: 86 VALVTTMVFFGYMVFSILFGLLADRYGRWKILLISFLWGAYFSLLTSFAPSYIWFVFLRT 145
Query: 139 AIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNEL------MIVIGILSAYISNYAFANV 192
+G +S S + E P RG ++ L+++ +++IG+ S I
Sbjct: 146 MVGCGVSGHSQGLIIK-TEFLPTKYRGYMLPLSQVFWLAGSLLIIGLASVIIPTI----- 199
Query: 193 FHGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRLRALS-DTTEELT 251
GW+++ + G++ +A F+P S RF V G AA L R+ ++ E
Sbjct: 200 --GWRWLIRVASIPGIILIVAFKFIPESARFNVSTGNTRAALATLERVAKMNRSVMPEGK 257
Query: 252 VIKSSLKDEYQYSFWDLFRSKDNMRTRIMI-----GLTLVFFVQITGQPNIL 298
+++ L E + F DL +K +RT + I G++ ++ I +L
Sbjct: 258 LVEPVL--EKRGRFADLLDAK-YLRTTLQIWVIWLGISFAYYGVILASAELL 306
>gi|24497499 solute carrier family 22 member 8 [Homo sapiens]
Length = 542
Score = 59.3 bits (142), Expect = 1e-08
Identities = 68/271 (25%), Positives = 116/271 (42%), Gaps = 24/271 (8%)
Query: 29 HPPWARGCGMFTFLSSVTAAVSGLLVGYELGIISGALLQIKTLLALSCHEQEMVVSSLVI 88
HPP A + + A+ L G+ +++ L+ S +EM S +
Sbjct: 78 HPPNA------SLPNDTQRAMEPCLDGWVYNSTKDSIVTEWDLVCNSNKLKEMAQSIFMA 131
Query: 89 GALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAIGVSISLSS 148
G L+ L G L DR+GRR + S LL S ++ + +V R G IS +
Sbjct: 132 GILIGGLVLGDLSDRFGRRPILTCSYLLLAASGSGAAFSPTFPIYMVFRFLCGFGISGIT 191
Query: 149 IATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAFANVFHGWKYM-FGLVIPLG 207
++T + E P R ++ + G + A+A W+++ + IP
Sbjct: 192 LSTVILNVEWVPTRMRAIMSTALGYCYTFG--QFILPGLAYA--IPQWRWLQLTVSIPFF 247
Query: 208 VLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRLRALSDTTEE-----LTVIKSSLKDEY- 261
V ++ ++ P S R+LV+ G+ A K+L R+ + EE L +K +L+ E
Sbjct: 248 VF-FLSSWWTPESIRWLVLSGKSSKALKILRRVAVFNGKKEEGERLSLEELKLNLQKEIS 306
Query: 262 ----QYSFWDLFRSKDNMRTRIMIGLTLVFF 288
+Y+ DLFR M R+ L+L +F
Sbjct: 307 LAKAKYTASDLFRIP--MLRRMTFCLSLAWF 335
>gi|207447703 solute carrier family 2 (facilitated glucose/fructose
transporter), member 5 isoform 2 [Homo sapiens]
Length = 244
Score = 58.9 bits (141), Expect = 1e-08
Identities = 31/107 (28%), Positives = 63/107 (58%), Gaps = 3/107 (2%)
Query: 81 MVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILS---LSYTVLIVGR 137
+ VS G + SL G L++++GR+ A++ ++ + ++++ S S+ ++I+ R
Sbjct: 73 VTVSMFPFGGFIGSLLVGPLVNKFGRKGALLFNNIFSIVPAILMGCSRVATSFELIIISR 132
Query: 138 IAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYI 184
+ +G+ +SS +Y+ E+AP++ RG L + +L I +GIL A I
Sbjct: 133 LLVGICAGVSSNVVPMYLGELAPKNLRGALGVVPQLFITVGILVAQI 179
>gi|4507005 solute carrier family 22 member 5 [Homo sapiens]
Length = 557
Score = 57.0 bits (136), Expect = 5e-08
Identities = 46/206 (22%), Positives = 89/206 (43%), Gaps = 9/206 (4%)
Query: 81 MVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAI 140
+ +S +G LL S G L DR+GR+ + ++ + S + I S ++ + +V + +
Sbjct: 144 LTISLFFVGVLLGSFISGQLSDRFGRKNVLFVTMGMQTGFSFLQIFSKNFEMFVVLFVLV 203
Query: 141 GVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAFANVFHGWKYMF 200
G+ + +A V EI + R + + L + I Y+ FA W+ +
Sbjct: 204 GMGQISNYVAAFVLGTEILGKSVR---IIFSTLGVCIFYAFGYMVLPLFAYFIRDWRMLL 260
Query: 201 GLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRLRALSDTTEELTVIKS----- 255
+ GVL +F+P SPR+L+ +G+ A ++ + + T+
Sbjct: 261 VALTMPGVLCVALWWFIPESPRWLISQGRFEEAEVIIRKAAKANGIVVPSTIFDPSELQD 320
Query: 256 -SLKDEYQYSFWDLFRSKDNMRTRIM 280
S K + ++ DL R+ + IM
Sbjct: 321 LSSKKQQSHNILDLLRTWNIRMVTIM 346
>gi|24308167 SV2 related protein [Homo sapiens]
Length = 548
Score = 57.0 bits (136), Expect = 5e-08
Identities = 65/290 (22%), Positives = 128/290 (44%), Gaps = 15/290 (5%)
Query: 33 ARGCGMFTFLSSVTAAVSGLLVGYELGIISGALLQIKTLLALSCHEQEMVVSSLVIGALL 92
A G G F + SV ++ + E+ I+S Q+ L + ++ S + +G +
Sbjct: 76 AIGFGKFQWKLSVLTGLAWMADAMEMMILSILAPQLHCEWRLPSWQVALLTSVVFVGMMS 135
Query: 93 ASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAIGVSISLSSIATC 152
+S G + D+YGR+T + +S ++ + Y+ ++V R +G I +
Sbjct: 136 SSTLWGNISDQYGRKTGLKISVLWTLYYGILSAFAPVYSWILVLRGLVGFGIGGVPQSVT 195
Query: 153 VYIAEIAPQHRRGLLVSLNELMIVIG-ILSAYISNYAFANVFHGWKYMFGL-VIPLGVLQ 210
+Y AE P R + L E+ IG + ++ + ++ GW+++ L +PL +L
Sbjct: 196 LY-AEFLPMKARAKCILLIEVFWAIGTVFEVVLAVFVMPSL--GWRWLLILSAVPL-LLF 251
Query: 211 AIAMYFLPPSPRFLVMKGQEGAASKVLGRLRALSDTTEELTVIKSSLKDEYQYSFWDLFR 270
A+ ++LP S R+ V+ G + A L R+ + L + S + E + DLF
Sbjct: 252 AVLCFWLPESARYDVLSGNQEKAIATLKRIATENGAPMPLGKLIIS-RQEDRGKMRDLFT 310
Query: 271 SKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNEAASLAS 320
T L++F+ + +Y +L + FQ+ + ++S
Sbjct: 311 PHFRWTT------LLLWFIWFSNA--FSYYGLVLLTTELFQAGDVCGISS 352
Score = 30.0 bits (66), Expect = 6.6
Identities = 23/81 (28%), Positives = 34/81 (41%)
Query: 100 LIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAIGVSISLSSIATCVYIAEIA 159
+IDR GR+ + L + SL+L + + VL + IS A VY E+
Sbjct: 393 IIDRLGRKKTMALCFVIFSFCSLLLFICVGRNVLTLLLFIARAFISGGFQAAYVYTPEVY 452
Query: 160 PQHRRGLLVSLNELMIVIGIL 180
P R L + M +G L
Sbjct: 453 PTATRALGLGTCSGMARVGAL 473
>gi|23510410 solute carrier family 22 member 1 isoform b [Homo
sapiens]
Length = 506
Score = 53.9 bits (128), Expect = 4e-07
Identities = 60/303 (19%), Positives = 133/303 (43%), Gaps = 21/303 (6%)
Query: 80 EMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIA 139
++ S L G L SL G DR+GR+ ++ + + + +++ S +Y +++ R+
Sbjct: 149 DLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLL 208
Query: 140 IGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAFANVFHGWKYM 199
G+ + +A I E R + + ++ +G+++ YA + W+++
Sbjct: 209 QGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPH----WRWL 264
Query: 200 FGLVIPLGVLQAIAMYF-LPPSPRFLVMKGQEGAASKVLGRLR----ALSDTTEELTVIK 254
L + L + Y+ +P SPR+L+ + + A K++ + L ++ ++
Sbjct: 265 -QLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKMLSLE 323
Query: 255 SSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNE 314
+ ++ SF DLFR+ +R R I + L F + Q IL +T +
Sbjct: 324 EDVTEKLSPSFADLFRT-PRLRKRTFILMYLWFTDSVLYQGLILHMGAT---------SG 373
Query: 315 AASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGIVNLNIH-MNFT 373
L +V++ A + +D VG + + + + A+ + M ++ ++H +N
Sbjct: 374 NLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIFISPDLHWLNII 433
Query: 374 HIC 376
+C
Sbjct: 434 IMC 436
>gi|4506999 solute carrier family 22 member 1 isoform a [Homo
sapiens]
Length = 554
Score = 53.9 bits (128), Expect = 4e-07
Identities = 60/303 (19%), Positives = 133/303 (43%), Gaps = 21/303 (6%)
Query: 80 EMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIA 139
++ S L G L SL G DR+GR+ ++ + + + +++ S +Y +++ R+
Sbjct: 149 DLFQSCLNAGFLFGSLGVGYFADRFGRKLCLLGTVLVNAVSGVLMAFSPNYMSMLLFRLL 208
Query: 140 IGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAFANVFHGWKYM 199
G+ + +A I E R + + ++ +G+++ YA + W+++
Sbjct: 209 QGLVSKGNWMAGYTLITEFVGSGSRRTVAIMYQMAFTVGLVALTGLAYALPH----WRWL 264
Query: 200 FGLVIPLGVLQAIAMYF-LPPSPRFLVMKGQEGAASKVLGRLR----ALSDTTEELTVIK 254
L + L + Y+ +P SPR+L+ + + A K++ + L ++ ++
Sbjct: 265 -QLAVSLPTFLFLLYYWCVPESPRWLLSQKRNTEAIKIMDHIAQKNGKLPPADLKMLSLE 323
Query: 255 SSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVLKSVGFQSNE 314
+ ++ SF DLFR+ +R R I + L F + Q IL +T +
Sbjct: 324 EDVTEKLSPSFADLFRT-PRLRKRTFILMYLWFTDSVLYQGLILHMGAT---------SG 373
Query: 315 AASLASTGVGVVKVISTIPATLLVDHVGSKTFLCIGSSVMAASLVTMGIVNLNIH-MNFT 373
L +V++ A + +D VG + + + + A+ + M ++ ++H +N
Sbjct: 374 NLYLDFLYSALVEIPGAFIALITIDRVGRIYPMAMSNLLAGAACLVMIFISPDLHWLNII 433
Query: 374 HIC 376
+C
Sbjct: 434 IMC 436
>gi|73695465 synaptic vesicle glycoprotein 2C [Homo sapiens]
Length = 727
Score = 53.1 bits (126), Expect = 7e-07
Identities = 50/216 (23%), Positives = 95/216 (43%), Gaps = 14/216 (6%)
Query: 35 GCGMFTFLSSVTAAVSGLLVGYELGIISGALLQIKTLLALSCHEQEMVVSSLVIGALLAS 94
G G F + ++ + G E+ ++ L +T L + + S + +G ++ +
Sbjct: 146 GHGRFQWALFFVLGMALMADGVEVFVVGFVLPSAETDLCIPNSGSGWLGSIVYLGMMVGA 205
Query: 95 LTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAIGVSISLSSIATCVY 154
G L D+ GR+ ++++ + G + + Y + R+ G I + Y
Sbjct: 206 FFWGGLADKVGRKQSLLICMSVNGFFAFLSSFVQGYGFFLFCRLLSGFGIGGAIPTVFSY 265
Query: 155 IAEIAPQHRRGLLVSLNELMIVIG------ILSAYISNYAF------ANVFHGWKYMFGL 202
AE+ + +RG +S + +IG + A I +Y + A FH W+ +F +
Sbjct: 266 FAEVLAREKRGEHLSWLCMFWMIGGIYASAMAWAIIPHYGWSFSMGSAYQFHSWR-VFVI 324
Query: 203 VIPLG-VLQAIAMYFLPPSPRFLVMKGQEGAASKVL 237
V L V +A+ F+P SPRFL+ G+ A +L
Sbjct: 325 VCALPCVSSVVALTFMPESPRFLLEVGKHDEAWMIL 360
>gi|24497490 solute carrier family 22 member 4 [Homo sapiens]
Length = 551
Score = 52.8 bits (125), Expect = 9e-07
Identities = 45/206 (21%), Positives = 89/206 (43%), Gaps = 25/206 (12%)
Query: 81 MVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAI 140
+ S +G LL S G L DR+GR+ + + + S + I S+S+ + V + +
Sbjct: 144 LTTSLFFVGVLLGSFVSGQLSDRFGRKNVLFATMAVQTGFSFLQIFSISWEMFTVLFVIV 203
Query: 141 GVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNY----AFANVFHGW 196
G+ + + + EI L S+ + +G+ + + Y FA W
Sbjct: 204 GMGQISNYVVAFILGTEI-------LGKSVRIIFSTLGVCTFFAVGYMLLPLFAYFIRDW 256
Query: 197 KYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVLGRLRALS---------DTT 247
+ + + GVL +F+P SPR+L+ + + A ++ + ++ D+
Sbjct: 257 RMLLLALTVPGVLCVPLWWFIPESPRWLISQRRFREAEDIIQKAAKMNNIAVPAVIFDSV 316
Query: 248 EELTVIKSSLKDEYQYSFWDLFRSKD 273
EEL +K + + DLFR+++
Sbjct: 317 EELNPLK-----QQKAFILDLFRTRN 337
>gi|7662270 synaptic vesicle protein 2B homolog [Homo sapiens]
Length = 683
Score = 52.0 bits (123), Expect = 2e-06
Identities = 49/218 (22%), Positives = 96/218 (44%), Gaps = 18/218 (8%)
Query: 35 GCGMFTFLSSVTAAVSGLLVGYELGIISGALLQIKTLLALSCHEQEMVVSSLVIGALLAS 94
G G F ++ ++ + G E+ ++S AL + + LS ++ M+ + +G + +
Sbjct: 103 GHGRFQWILFFVLGLALMADGVEVFVVSFALPSAEKDMCLSSSKKGMLGMIVYLGMMAGA 162
Query: 95 LTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAIGVSISLSSIATCVY 154
G L D+ GR+ + +S + + + Y + R+ G+ I + Y
Sbjct: 163 FILGGLADKLGRKRVLSMSLAVNASFASLSSFVQGYGAFLFCRLISGIGIGGALPIVFAY 222
Query: 155 IAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAFANV--------------FHGWKYMF 200
+E + +RG +S + + G L Y S A++ + FH W+ +F
Sbjct: 223 FSEFLSREKRGEHLSWLGIFWMTGGL--YASAMAWSIIPHYGWGFSMGTNYHFHSWR-VF 279
Query: 201 GLVIPLG-VLQAIAMYFLPPSPRFLVMKGQEGAASKVL 237
+V L + +A+ F+P SPRFL+ G+ A +L
Sbjct: 280 VIVCALPCTVSMVALKFMPESPRFLLEMGKHDEAWMIL 317
>gi|166197673 solute carrier family 22, member 15 [Homo sapiens]
Length = 547
Score = 51.6 bits (122), Expect = 2e-06
Identities = 73/291 (25%), Positives = 121/291 (41%), Gaps = 28/291 (9%)
Query: 71 LLALSCHEQEMVVSSLVIGALLASLTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSY 130
L+A ++ S G + ++ G L DR+GR+ + L L ++ S SY
Sbjct: 103 LIANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFAIANGFSPSY 162
Query: 131 TVLIVGRIAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVIGILSAYISNYAFA 190
V R +G+ S+ V + E L S+ L +G I+ YA
Sbjct: 163 EFFAVTRFLVGMMNGGMSLVAFVLLNECVGTAYWALAGSIGGLFFAVG-----IAQYALL 217
Query: 191 NVF-HGWKYMFGLVIPLGVLQAIAMYFLPPSPRFLVMKGQEGAASKVL----GRLRALSD 245
F W+ + LV G + + F+P SPR+L +G+ A + L R R L
Sbjct: 218 GYFIRSWRTLAILVNLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALYLIAKRNRKLKC 277
Query: 246 TTEELTVIKSSLKDEYQYSFWDLFRSKDNMRTRIMIGLTLVFFVQITGQPNILFYASTVL 305
T S ++ SF DLF R R+++G TL+ I ++++Y T L
Sbjct: 278 TFSLTHPANRSCRE--TGSFLDLF------RYRVLLGHTLILMF-IWFVCSLVYYGLT-L 327
Query: 306 KSVGFQSNEAASLASTGVGVVKVISTIPATLLVDH--VGSK----TFLCIG 350
+ + A+LA + G++++ S L++ G K FLC+G
Sbjct: 328 SAGDLGGSIYANLALS--GLIEIPSYPLCIYLINQKWFGRKRTLSAFLCLG 376
>gi|216548223 synaptic vesicle glycoprotein 2 [Homo sapiens]
Length = 742
Score = 51.2 bits (121), Expect = 3e-06
Identities = 54/216 (25%), Positives = 92/216 (42%), Gaps = 14/216 (6%)
Query: 35 GCGMFTFLSSVTAAVSGLLVGYELGIISGALLQIKTLLALSCHEQEMVVSSLVIGALLAS 94
G G F + ++ + G E+ ++ L + + LS + M+ + +G ++ +
Sbjct: 160 GHGRFQWTLYFVLGLALMADGVEVFVVGFVLPSAEKDMCLSDSNKGMLGLIVYLGMMVGA 219
Query: 95 LTGGVLIDRYGRRTAIILSSCLLGLGSLVLILSLSYTVLIVGRIAIGVSISLSSIATCVY 154
G L DR GRR +++S + + + Y + R+ GV I S Y
Sbjct: 220 FLWGGLADRLGRRQCLLISLSVNSVFAFFSSFVQGYGTFLFCRLLSGVGIGGSIPIVFSY 279
Query: 155 IAEIAPQHRRGLLVSLNELMIVIG------ILSAYISNYAF------ANVFHGWKYMFGL 202
+E Q +RG +S + +IG + A I +Y + A FH W+ +F L
Sbjct: 280 FSEFLAQEKRGEHLSWLCMFWMIGGVYAAAMAWAIIPHYGWSFQMGSAYQFHSWR-VFVL 338
Query: 203 VIPLGVLQAI-AMYFLPPSPRFLVMKGQEGAASKVL 237
V + AI A+ P SPRF + G+ A VL
Sbjct: 339 VCAFPSVFAIGALTTQPESPRFFLENGKHDEAWMVL 374
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,895,570
Number of Sequences: 37866
Number of extensions: 845526
Number of successful extensions: 2486
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 26
Number of HSP's that attempted gapping in prelim test: 2346
Number of HSP's gapped (non-prelim): 112
length of query: 617
length of database: 18,247,518
effective HSP length: 108
effective length of query: 509
effective length of database: 14,157,990
effective search space: 7206416910
effective search space used: 7206416910
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.