Search of human proteins with 21389573

Search of human proteins with 21389573

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21389573 transmembrane emp24 protein transport domain
containing 6 [Homo sapiens]
         (240 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21389573 transmembrane emp24 protein transport domain contain...   503   e-143
gi|5803040 interleukin 1 receptor-like 1 ligand precursor [Homo ...    60   1e-09
gi|19923442 transmembrane emp24 protein transport domain contain...    59   5e-09
gi|32996709 transmembrane emp24 protein transport domain contain...    47   1e-05
gi|33457308 transmembrane emp24 protein transport domain contain...    47   2e-05
gi|6679189 transmembrane emp24 domain containing 3 [Homo sapiens]      45   6e-05
gi|39725636 transmembrane emp24 protein transport domain contain...    44   1e-04
gi|45387953 potassium channel tetramerization domain containing ...    33   0.17 
gi|5803149 coated vesicle membrane protein [Homo sapiens]              33   0.17 
gi|33188445 microfilament and actin filament cross-linker protei...    28   7.1  
gi|57164962 inositol 1,4,5-triphosphate receptor interacting pro...    28   9.2  
gi|57164960 inositol 1,4,5-triphosphate receptor interacting pro...    28   9.2  

>gi|21389573 transmembrane emp24 protein transport domain containing
           6 [Homo sapiens]
          Length = 240

 Score =  503 bits (1295), Expect = e-143
 Identities = 240/240 (100%), Positives = 240/240 (100%)

Query: 1   MSPLLFGAGLVVLNLVTSARSQKTEPLSGSGDQPLFRGADRYDFAIMIPPGGTECFWQFA 60
           MSPLLFGAGLVVLNLVTSARSQKTEPLSGSGDQPLFRGADRYDFAIMIPPGGTECFWQFA
Sbjct: 1   MSPLLFGAGLVVLNLVTSARSQKTEPLSGSGDQPLFRGADRYDFAIMIPPGGTECFWQFA 60

Query: 61  HQTGYFYFSCEVQRTVGMSHDRHVAATAHNPQGFLIDTSQGVRGQINFSTQETGFYQLCL 120
           HQTGYFYFSCEVQRTVGMSHDRHVAATAHNPQGFLIDTSQGVRGQINFSTQETGFYQLCL
Sbjct: 61  HQTGYFYFSCEVQRTVGMSHDRHVAATAHNPQGFLIDTSQGVRGQINFSTQETGFYQLCL 120

Query: 121 SNQHNHFGSVQVYLNFGVFYEGPETDHKQKERKQLNDTLDAIEDGTQKVQNNIFHMWRYY 180
           SNQHNHFGSVQVYLNFGVFYEGPETDHKQKERKQLNDTLDAIEDGTQKVQNNIFHMWRYY
Sbjct: 121 SNQHNHFGSVQVYLNFGVFYEGPETDHKQKERKQLNDTLDAIEDGTQKVQNNIFHMWRYY 180

Query: 181 NFARMRKMADFFLIQSNYNYVNWWSTAQSLVIILSGILQLYFLKRLFNVPTTTDTKKPRC 240
           NFARMRKMADFFLIQSNYNYVNWWSTAQSLVIILSGILQLYFLKRLFNVPTTTDTKKPRC
Sbjct: 181 NFARMRKMADFFLIQSNYNYVNWWSTAQSLVIILSGILQLYFLKRLFNVPTTTDTKKPRC 240


>gi|5803040 interleukin 1 receptor-like 1 ligand precursor [Homo
           sapiens]
          Length = 227

 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 51/217 (23%), Positives = 91/217 (41%), Gaps = 22/217 (10%)

Query: 27  LSGSGDQPLFRGADRYDFAIMIPPGGTECFWQFAHQTGYFYFSCEVQRTVGMSHDRHVAA 86
           + G+G  P+  G    +F  ++P G  +CF+Q A          +V    G+  D     
Sbjct: 21  VGGAGPPPIQDG----EFTFLLPAGRKQCFYQSAPANASLETEYQVIGGAGLDVD----F 72

Query: 87  TAHNPQG-FLIDTSQGVRGQINFSTQETGFYQLCLSNQHNHFGSVQVYLNFGVFYEGPET 145
           T  +PQG  L+  S+   G       E G Y+LC  N  +      V+  F + ++  + 
Sbjct: 73  TLESPQGVLLVSESRKADGVHTVEPTEAGDYKLCFDNSFSTISEKLVF--FELIFDSLQD 130

Query: 146 DHKQK-------ERKQLNDTLDAIEDGTQKVQNNIFHMWRYYNFARMRKMADFFLIQSNY 198
           D + +         + L+  ++ I++  + ++  +    +     R  +  D  L + N 
Sbjct: 131 DEEVEGWAEAVEPEEMLDVKMEDIKESIETMRTRLERSIQMLTLLRAFEARDRNLQEGNL 190

Query: 199 NYVNWWSTAQSLVIILSGILQLYFLKRLFN----VPT 231
             VN+WS     V++L  +LQ+  LKR F     VPT
Sbjct: 191 ERVNFWSAVNVAVLLLVAVLQVCTLKRFFQDKRPVPT 227


>gi|19923442 transmembrane emp24 protein transport domain containing
           5 [Homo sapiens]
          Length = 229

 Score = 58.5 bits (140), Expect = 5e-09
 Identities = 41/191 (21%), Positives = 78/191 (40%), Gaps = 10/191 (5%)

Query: 43  DFAIMIPPGGTECFWQFAHQTGYFYFSCEVQRTVGMSHDRHVAATAHNPQGFLIDTSQGV 102
           DF   +P G  ECF+Q            +V    G+  D H+A+    P+G  +   Q  
Sbjct: 35  DFTFTLPAGQKECFYQPMPLKASLEIEYQVLDGAGLDIDFHLAS----PEGKTLVFEQRK 90

Query: 103 RGQINFSTQETGFYQLCLSNQHNHFGSVQVYLNFGVFYEGPETDHKQKERKQLNDT---- 158
              ++    E G Y  C  N  +      ++    +   G +   ++  +K +  T    
Sbjct: 91  SDGVHTVETEVGDYMFCFDNTFSTISEKVIFFELILDNMGEQAQEQEDWKKYITGTDILD 150

Query: 159 --LDAIEDGTQKVQNNIFHMWRYYNFARMRKMADFFLIQSNYNYVNWWSTAQSLVIILSG 216
             L+ I +    +++ +          R  +  D  + +SN++ VN+WS    +V+++  
Sbjct: 151 MKLEDILESINSIKSRLSKSGHIQILLRAFEARDRNIQESNFDRVNFWSMVNLVVMVVVS 210

Query: 217 ILQLYFLKRLF 227
            +Q+Y LK LF
Sbjct: 211 AIQVYMLKSLF 221


>gi|32996709 transmembrane emp24 protein transport domain containing
           7 [Homo sapiens]
          Length = 224

 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 42/192 (21%), Positives = 80/192 (41%), Gaps = 14/192 (7%)

Query: 48  IPPGGTECFWQFAHQTGYFYFSCEVQRTVGMSHDRHVAATAHNPQG-FLIDTSQGVRGQI 106
           +P    +CF++   Q      + E Q   G  +D  V     +P G  L    +      
Sbjct: 41  LPDNAKQCFYEDIAQGTKC--TLEFQVITGGHYD--VDCRLEDPDGKVLYKEMKKQYDSF 96

Query: 107 NFSTQETGFYQLCLSNQHNHFGSVQVYLNFGVFYEGP--ETDHKQKERKQLNDTLDAIED 164
            F+  + G Y+ C SN+ + F    VY +F V  + P   ++++     Q+     +I +
Sbjct: 97  TFTASKNGTYKFCFSNEFSTFTHKTVYFDFQVGEDPPLFPSENRVSALTQMESACVSIHE 156

Query: 165 GTQKVQNNIFHMWRYYNFARMRKMADFFLIQSNYNYVNWWSTAQSLVIILSGILQLYFLK 224
             + V +       Y    R+R+       +     V +WS  ++L++++  I Q++ LK
Sbjct: 157 ALKSVID-------YQTHFRLREAQGRSRAEDLNTRVAYWSVGEALILLVVSIGQVFLLK 209

Query: 225 RLFNVPTTTDTK 236
             F+   TT T+
Sbjct: 210 SFFSDKRTTTTR 221


>gi|33457308 transmembrane emp24 protein transport domain containing
           4 [Homo sapiens]
          Length = 227

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 36/147 (24%), Positives = 69/147 (46%), Gaps = 17/147 (11%)

Query: 90  NPQGFLIDTSQ-GVRGQINFSTQETGFYQLCLSNQHNHF-----GSVQVYLNFGVFYEG- 142
           +P G ++ + Q G  G+  F++   G +Q+CL +          G ++V+L+  V     
Sbjct: 83  DPDGKVVLSRQYGSEGRFTFTSHTPGDHQICLHSNSTRMALFAGGKLRVHLDIQVGEHAN 142

Query: 143 --PETDHKQKERKQLNDTLDAIEDGTQKVQNNIFHMWRYYNFARMRKMADFFLIQSNYNY 200
             PE   K K        L  ++   +++ + +  + +  ++ R R+       +S    
Sbjct: 143 NYPEIAAKDK--------LTELQLRARQLLDQVEQIQKEQDYQRYREERFRLTSESTNQR 194

Query: 201 VNWWSTAQSLVIILSGILQLYFLKRLF 227
           V WWS AQ++++IL+GI Q+  LK  F
Sbjct: 195 VLWWSIAQTVILILTGIWQMRHLKSFF 221


>gi|6679189 transmembrane emp24 domain containing 3 [Homo sapiens]
          Length = 217

 Score = 45.1 bits (105), Expect = 6e-05
 Identities = 41/184 (22%), Positives = 74/184 (40%), Gaps = 15/184 (8%)

Query: 48  IPPGGTECFWQFAHQTGYFYFSCEVQRTVGMSHDRHVAATAHNPQGFLI-DTSQGVRGQI 106
           +P    +CF +   Q     FS + Q   G  +D  V     +PQG  I   ++      
Sbjct: 33  LPDNAKQCFHEEVEQG--VKFSLDYQVITGGHYD--VDCYVEDPQGNTIYRETKKQYDSF 88

Query: 107 NFSTQETGFYQLCLSNQHNHFGSVQVYLNFGVFYEG---PETDHKQKERKQLNDTLDAIE 163
            +  +  G YQ C SN+ + F    VY +F V  E    P+  ++     Q+      I 
Sbjct: 89  TYRAEVKGVYQFCFSNEFSTFSHKTVYFDFQVGDEPPILPDMGNRVTALTQMESACVTIH 148

Query: 164 DGTQKVQNNIFHMWRYYNFARMRKMADFFLIQSNYNYVNWWSTAQSLVIILSGILQLYFL 223
           +  + V ++  H        R+R+  D    +   + V++WS  +++ + +    Q+  L
Sbjct: 149 EALKTVIDSQTHY-------RLREAQDRARAEDLNSRVSYWSVGETIALFVVSFSQVLLL 201

Query: 224 KRLF 227
           K  F
Sbjct: 202 KSFF 205


>gi|39725636 transmembrane emp24 protein transport domain containing
           9 [Homo sapiens]
          Length = 235

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 31/132 (23%), Positives = 60/132 (45%), Gaps = 10/132 (7%)

Query: 101 GVRGQINFSTQETGFYQLCLSNQHNHF-----GSVQVYLNFGVFYEGPETDHKQKERKQL 155
           G  G+  F++   G +Q+CL +    F     G ++V+L+  V       D+ +   K  
Sbjct: 103 GSEGRFTFTSHTPGEHQICLHSNSTKFSLFAGGMLRVHLDIQVGEHA--NDYAEIAAK-- 158

Query: 156 NDTLDAIEDGTQKVQNNIFHMWRYYNFARMRKMADFFLIQSNYNYVNWWSTAQSLVIILS 215
            D L  ++   +++   +  + +  N+ R R+       +S    V WWS  Q+L+++  
Sbjct: 159 -DKLSELQLRVRQLVEQVEQIQKEQNYQRWREERFRQTSESTNQRVLWWSILQTLILVAI 217

Query: 216 GILQLYFLKRLF 227
           G+ Q+  LK  F
Sbjct: 218 GVWQMRHLKSFF 229


>gi|45387953 potassium channel tetramerization domain containing 18
           [Homo sapiens]
          Length = 426

 Score = 33.5 bits (75), Expect = 0.17
 Identities = 18/68 (26%), Positives = 32/68 (47%), Gaps = 1/68 (1%)

Query: 144 ETDHKQKERKQLNDTLDAIEDGTQKVQNNIFHMWRYYNFARMRKMADFFLIQSNYNYVNW 203
           +TD      KQL   + +     ++  NN+ ++W YY+ A ++KM D F        V++
Sbjct: 166 KTDGTDAIEKQLGGRIHSKGIFKREAGNNVQYIWSYYSVAELKKMMDAFDAWEGKG-VSY 224

Query: 204 WSTAQSLV 211
           W     L+
Sbjct: 225 WRVPHELI 232


>gi|5803149 coated vesicle membrane protein [Homo sapiens]
          Length = 201

 Score = 33.5 bits (75), Expect = 0.17
 Identities = 26/126 (20%), Positives = 54/126 (42%), Gaps = 6/126 (4%)

Query: 104 GQINFSTQETGFYQLCLSNQHNHFGSVQVYLNFGVFYEGPETDHKQKERKQLNDTLDAIE 163
           G+  F+    G Y+ C SN+ +      V     +  E P+    + E  Q     + +E
Sbjct: 78  GKYTFAAHMDGTYKFCFSNRMSTMTPKIVMFTIDIG-EAPKGQDMETEAHQ-----NKLE 131

Query: 164 DGTQKVQNNIFHMWRYYNFARMRKMADFFLIQSNYNYVNWWSTAQSLVIILSGILQLYFL 223
           +   ++   +  +     +  +R+     +  +  + V  WS  ++LV++   + Q+Y+L
Sbjct: 132 EMINELAVAMTAVKHEQEYMEVRERIHRAINDNTNSRVVLWSFFEALVLVAMTLGQIYYL 191

Query: 224 KRLFNV 229
           KR F V
Sbjct: 192 KRFFEV 197


>gi|33188445 microfilament and actin filament cross-linker protein
           isoform a [Homo sapiens]
          Length = 5430

 Score = 28.1 bits (61), Expect = 7.1
 Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 12/78 (15%)

Query: 147 HKQKERKQLNDTLDAIE-------DGTQKVQNNIFHMWRYYNFARMRKMADFFLIQSNYN 199
           H+QK+RK  +  LD  E       D   +VQ   F  W   +  ++RK      I   Y 
Sbjct: 50  HEQKKRKSQDSVLDPAERAVVRVADERDRVQKKTFTKWVNKHLMKVRKH-----INDLYE 104

Query: 200 YVNWWSTAQSLVIILSGI 217
            +       SL+ +LSGI
Sbjct: 105 DLRDGHNLISLLEVLSGI 122


>gi|57164962 inositol 1,4,5-triphosphate receptor interacting
           protein-like 1 isoform 1 [Homo sapiens]
          Length = 563

 Score = 27.7 bits (60), Expect = 9.2
 Identities = 10/28 (35%), Positives = 17/28 (60%)

Query: 39  ADRYDFAIMIPPGGTECFWQFAHQTGYF 66
           A +YDF + +PP  T C  +  +++G F
Sbjct: 342 AHKYDFKLSLPPSTTSCKLRLDYRSGRF 369


>gi|57164960 inositol 1,4,5-triphosphate receptor interacting
           protein-like 1 isoform 2 [Homo sapiens]
          Length = 555

 Score = 27.7 bits (60), Expect = 9.2
 Identities = 10/28 (35%), Positives = 17/28 (60%)

Query: 39  ADRYDFAIMIPPGGTECFWQFAHQTGYF 66
           A +YDF + +PP  T C  +  +++G F
Sbjct: 334 AHKYDFKLSLPPSTTSCKLRLDYRSGRF 361


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,274,683
Number of Sequences: 37866
Number of extensions: 395441
Number of successful extensions: 700
Number of sequences better than 10.0: 12
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 1
Number of HSP's that attempted gapping in prelim test: 683
Number of HSP's gapped (non-prelim): 14
length of query: 240
length of database: 18,247,518
effective HSP length: 99
effective length of query: 141
effective length of database: 14,498,784
effective search space: 2044328544
effective search space used: 2044328544
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.