BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|21361914 semaphorin B [Homo sapiens] (761 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|21361914 semaphorin B [Homo sapiens] 1557 0.0 gi|39777610 semaphorin 4B precursor [Homo sapiens] 471 e-133 gi|39777608 semaphorin 4B precursor [Homo sapiens] 471 e-133 gi|157388902 semaphorin 4C [Homo sapiens] 401 e-111 gi|214010218 semaphorin 4D isoform 1 [Homo sapiens] 385 e-106 gi|214010220 semaphorin 4D isoform 2 [Homo sapiens] 376 e-104 gi|28872814 semaphorin 4G [Homo sapiens] 341 2e-93 gi|19923279 semaphorin W [Homo sapiens] 337 2e-92 gi|5174673 semaphorin 3A precursor [Homo sapiens] 301 1e-81 gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens] 298 1e-80 gi|54607089 semaphorin 3B isoform 2 precursor [Homo sapiens] 297 3e-80 gi|188497703 semaphorin 3F [Homo sapiens] 291 2e-78 gi|41406086 semaphorin 3D [Homo sapiens] 288 1e-77 gi|5454048 semaphorin 3C [Homo sapiens] 282 7e-76 gi|91982767 semaphorin 5B isoform 1 [Homo sapiens] 267 3e-71 gi|9910362 semaphorin sem2 [Homo sapiens] 263 6e-70 gi|147904700 semaphorin 5A [Homo sapiens] 253 6e-67 gi|6912650 semaphorin 3E [Homo sapiens] 252 1e-66 gi|11991660 sema domain, transmembrane domain (TM), and cytoplas... 244 2e-64 gi|19718780 semaphorin 6B precursor [Homo sapiens] 241 2e-63 gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens] 234 3e-61 gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens] 233 5e-61 gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens] 233 5e-61 gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens] 233 5e-61 gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens] 229 7e-60 gi|16306552 semaphorin Y [Homo sapiens] 218 2e-56 gi|24234732 semaphorin 6D isoform 6 precursor [Homo sapiens] 197 4e-50 gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens] 166 7e-41 gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens] 164 2e-40 gi|225637524 semaphorin 7A isoform 3 [Homo sapiens] 152 9e-37 >gi|21361914 semaphorin B [Homo sapiens] Length = 761 Score = 1557 bits (4031), Expect = 0.0 Identities = 761/761 (100%), Positives = 761/761 (100%) Query: 1 MALPALGLDPWSLLGLFLFQLLQLLLPTTTAGGGGQGPMPRVRYYAGDERRALSFFHQKG 60 MALPALGLDPWSLLGLFLFQLLQLLLPTTTAGGGGQGPMPRVRYYAGDERRALSFFHQKG Sbjct: 1 MALPALGLDPWSLLGLFLFQLLQLLLPTTTAGGGGQGPMPRVRYYAGDERRALSFFHQKG 60 Query: 61 LQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVPRLKNMIPWPASDRKKSECAFKKKSN 120 LQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVPRLKNMIPWPASDRKKSECAFKKKSN Sbjct: 61 LQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVPRLKNMIPWPASDRKKSECAFKKKSN 120 Query: 121 ETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDP 180 ETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDP Sbjct: 121 ETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDP 180 Query: 181 AHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNFLRWLHHDASFVAAIPST 240 AHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNFLRWLHHDASFVAAIPST Sbjct: 181 AHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNFLRWLHHDASFVAAIPST 240 Query: 241 QVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCTQPGQLP 300 QVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCTQPGQLP Sbjct: 241 QVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCTQPGQLP 300 Query: 301 FNVIRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKE 360 FNVIRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKE Sbjct: 301 FNVIRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKE 360 Query: 361 TSRWTTYRGPETNPRPGSCSVGPSSDKALTFMKDHFLMDEQVVGTPLLVKSGVEYTRLAV 420 TSRWTTYRGPETNPRPGSCSVGPSSDKALTFMKDHFLMDEQVVGTPLLVKSGVEYTRLAV Sbjct: 361 TSRWTTYRGPETNPRPGSCSVGPSSDKALTFMKDHFLMDEQVVGTPLLVKSGVEYTRLAV 420 Query: 421 ETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSAHLVEEIQLFPDPEPVRNLQLAPTQGA 480 ETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSAHLVEEIQLFPDPEPVRNLQLAPTQGA Sbjct: 421 ETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSAHLVEEIQLFPDPEPVRNLQLAPTQGA 480 Query: 481 VFVGFSGGVWRVPRANCSVYESCVDCVLARDPHCAWDPESRTCCLLSAPNLNSWKQDMER 540 VFVGFSGGVWRVPRANCSVYESCVDCVLARDPHCAWDPESRTCCLLSAPNLNSWKQDMER Sbjct: 481 VFVGFSGGVWRVPRANCSVYESCVDCVLARDPHCAWDPESRTCCLLSAPNLNSWKQDMER 540 Query: 541 GNPEWACASGPMSRSLRPQSRPQIIKEVLAVPNSILELPCPHLSALASYYWSHGPAAVPE 600 GNPEWACASGPMSRSLRPQSRPQIIKEVLAVPNSILELPCPHLSALASYYWSHGPAAVPE Sbjct: 541 GNPEWACASGPMSRSLRPQSRPQIIKEVLAVPNSILELPCPHLSALASYYWSHGPAAVPE 600 Query: 601 ASSTVYNGSLLLIVQDGVGGLYQCWATENGFSYPVISYWVDSQDQTLALDPELAGIPREH 660 ASSTVYNGSLLLIVQDGVGGLYQCWATENGFSYPVISYWVDSQDQTLALDPELAGIPREH Sbjct: 601 ASSTVYNGSLLLIVQDGVGGLYQCWATENGFSYPVISYWVDSQDQTLALDPELAGIPREH 660 Query: 661 VKVPLTRVSGGAALAAQQSYWPHFVTVTVLFALVLSGALIILVASPLRALRARGKVQGCE 720 VKVPLTRVSGGAALAAQQSYWPHFVTVTVLFALVLSGALIILVASPLRALRARGKVQGCE Sbjct: 661 VKVPLTRVSGGAALAAQQSYWPHFVTVTVLFALVLSGALIILVASPLRALRARGKVQGCE 720 Query: 721 TLRPGEKAPLSREQHLQSPKECRTSASDVDADNNCLGTEVA 761 TLRPGEKAPLSREQHLQSPKECRTSASDVDADNNCLGTEVA Sbjct: 721 TLRPGEKAPLSREQHLQSPKECRTSASDVDADNNCLGTEVA 761 >gi|39777610 semaphorin 4B precursor [Homo sapiens] Length = 837 Score = 471 bits (1213), Expect = e-133 Identities = 297/760 (39%), Positives = 422/760 (55%), Gaps = 59/760 (7%) Query: 5 ALGLDPWSLLGLFLFQLLQLLLPTTTAGGGGQGPMPRVRYYAGDERRALSFFHQKGLQDF 64 AL P LL L L LLQ PT PR+ G E R F + + ++ Sbjct: 18 ALPPRPPLLLLLLLLLLLQPPPPTWALS-------PRISLPLGSEERPFLRFEAEHISNY 70 Query: 65 DTLLLSGDGNTLYVGAREAILALDIQDPGVPRLKNM-IPWPASDRKKSECAFKKKSNETQ 123 LLLS DG TLYVGAREA+ AL +P + + W A KK +C+FK K + Sbjct: 71 TALLLSRDGRTLYVGAREALFALSSNLSFLPGGEYQELLWGADAEKKQQCSFKGKDPQRD 130 Query: 124 CFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVM--EGKGQSPFDPA 181 C N+I++L+ + +HL+TCGT AFSP CT+I +++ L + V+ +GKG+ PFDP Sbjct: 131 CQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLEDGKGRCPFDPN 190 Query: 182 HKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNFLRWLHHDASFVAA--IPS 239 K TA++VDG LY+GT+++F G++P + R+ +P KT++ L WL D +FVA+ IP Sbjct: 191 FKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPT-KTESSLNWLQ-DPAFVASAYIPE 248 Query: 240 T--------QVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQL 291 + +YFFF ET EF+FFE SR+AR+CK D GGE++LQ++WT+FLKAQL Sbjct: 249 SLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQQRWTSFLKAQL 308 Query: 292 LCTQPGQ-LPFNVIRHAVLLPADSPTAPH-----IYAVFTSQWQVGGTRSSAVCAFSLLD 345 LC++P PFNV++ L SP+ Y VFTSQW G T SAVC F++ D Sbjct: 309 LCSRPDDGFPFNVLQDVFTL---SPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCVFTMKD 365 Query: 346 IERVFKGKYKELNKETSRWTTYRGPETNPRPGSCSVGPS-----------SDKALTFMKD 394 ++RVF G YKE+N+ET +W T P PRPG+C + D+ L F+KD Sbjct: 366 VQRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRVLNFLKD 425 Query: 395 HFLMDEQVVGTPLLVKSGVEYTRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSA 454 HFLMD QV LL++ Y R+AV GL H++ V++LGT G LHKAV G Sbjct: 426 HFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLH-HTYDVLFLGTGDGRLHKAVSVG-PRV 483 Query: 455 HLVEEIQLFPDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESCVDCVLARDPHC 514 H++EE+Q+F +PV+NL L +G ++ GV +VP ANCS+Y SC DC+LARDP+C Sbjct: 484 HIIEELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARDPYC 543 Query: 515 AWDPESRTCCLLSAPNL--NSWKQDMERGNPEWAC-ASGPMSRSLRPQSRPQIIKEVLAV 571 AW S L P L W QD+E + + C AS +S S P + ++V Sbjct: 544 AWSGSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSASSVVSPSFVPTGE-KPCEQVQFQ 602 Query: 572 PNSILELPCPHLSALASYYWSHGPAAVPEASS--TVYNGSLLLIVQDGVGGLYQCWATEN 629 PN++ L CP LS LA+ W A V ++S + G LLL+ +G +QCW+ E Sbjct: 603 PNTVNTLACPLLSNLATRLWLRNGAPVNASASCHVLPTGDLLLVGTQQLGE-FQCWSLEE 661 Query: 630 GFSYPVISYWVDSQDQTLALDPELAG-IPREHVKVPLTRVS----GGAALAAQQSYWPHF 684 GF V SY + + +A + G +P V + +RVS G A+ A +SYW F Sbjct: 662 GFQQLVASYCPEVVEDGVADQTDEGGSVP---VIISTSRVSAPAGGKASWGADRSYWKEF 718 Query: 685 VTVTVLFALVLSGALIILVASPLRALRARGKVQGCETLRP 724 + + LF L + ++ L+ +++ K C ++ P Sbjct: 719 LVMCTLFVLAVLLPVLFLLYRHRNSMKVFLKQGECASVHP 758 >gi|39777608 semaphorin 4B precursor [Homo sapiens] Length = 837 Score = 471 bits (1213), Expect = e-133 Identities = 297/760 (39%), Positives = 422/760 (55%), Gaps = 59/760 (7%) Query: 5 ALGLDPWSLLGLFLFQLLQLLLPTTTAGGGGQGPMPRVRYYAGDERRALSFFHQKGLQDF 64 AL P LL L L LLQ PT PR+ G E R F + + ++ Sbjct: 18 ALPPRPPLLLLLLLLLLLQPPPPTWALS-------PRISLPLGSEERPFLRFEAEHISNY 70 Query: 65 DTLLLSGDGNTLYVGAREAILALDIQDPGVPRLKNM-IPWPASDRKKSECAFKKKSNETQ 123 LLLS DG TLYVGAREA+ AL +P + + W A KK +C+FK K + Sbjct: 71 TALLLSRDGRTLYVGAREALFALSSNLSFLPGGEYQELLWGADAEKKQQCSFKGKDPQRD 130 Query: 124 CFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVM--EGKGQSPFDPA 181 C N+I++L+ + +HL+TCGT AFSP CT+I +++ L + V+ +GKG+ PFDP Sbjct: 131 CQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLEDGKGRCPFDPN 190 Query: 182 HKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNFLRWLHHDASFVAA--IPS 239 K TA++VDG LY+GT+++F G++P + R+ +P KT++ L WL D +FVA+ IP Sbjct: 191 FKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPT-KTESSLNWLQ-DPAFVASAYIPE 248 Query: 240 T--------QVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQL 291 + +YFFF ET EF+FFE SR+AR+CK D GGE++LQ++WT+FLKAQL Sbjct: 249 SLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQQRWTSFLKAQL 308 Query: 292 LCTQPGQ-LPFNVIRHAVLLPADSPTAPH-----IYAVFTSQWQVGGTRSSAVCAFSLLD 345 LC++P PFNV++ L SP+ Y VFTSQW G T SAVC F++ D Sbjct: 309 LCSRPDDGFPFNVLQDVFTL---SPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCVFTMKD 365 Query: 346 IERVFKGKYKELNKETSRWTTYRGPETNPRPGSCSVGPS-----------SDKALTFMKD 394 ++RVF G YKE+N+ET +W T P PRPG+C + D+ L F+KD Sbjct: 366 VQRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRVLNFLKD 425 Query: 395 HFLMDEQVVGTPLLVKSGVEYTRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSA 454 HFLMD QV LL++ Y R+AV GL H++ V++LGT G LHKAV G Sbjct: 426 HFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLH-HTYDVLFLGTGDGRLHKAVSVG-PRV 483 Query: 455 HLVEEIQLFPDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESCVDCVLARDPHC 514 H++EE+Q+F +PV+NL L +G ++ GV +VP ANCS+Y SC DC+LARDP+C Sbjct: 484 HIIEELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARDPYC 543 Query: 515 AWDPESRTCCLLSAPNL--NSWKQDMERGNPEWAC-ASGPMSRSLRPQSRPQIIKEVLAV 571 AW S L P L W QD+E + + C AS +S S P + ++V Sbjct: 544 AWSGSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSASSVVSPSFVPTGE-KPCEQVQFQ 602 Query: 572 PNSILELPCPHLSALASYYWSHGPAAVPEASS--TVYNGSLLLIVQDGVGGLYQCWATEN 629 PN++ L CP LS LA+ W A V ++S + G LLL+ +G +QCW+ E Sbjct: 603 PNTVNTLACPLLSNLATRLWLRNGAPVNASASCHVLPTGDLLLVGTQQLGE-FQCWSLEE 661 Query: 630 GFSYPVISYWVDSQDQTLALDPELAG-IPREHVKVPLTRVS----GGAALAAQQSYWPHF 684 GF V SY + + +A + G +P V + +RVS G A+ A +SYW F Sbjct: 662 GFQQLVASYCPEVVEDGVADQTDEGGSVP---VIISTSRVSAPAGGKASWGADRSYWKEF 718 Query: 685 VTVTVLFALVLSGALIILVASPLRALRARGKVQGCETLRP 724 + + LF L + ++ L+ +++ K C ++ P Sbjct: 719 LVMCTLFVLAVLLPVLFLLYRHRNSMKVFLKQGECASVHP 758 >gi|157388902 semaphorin 4C [Homo sapiens] Length = 833 Score = 401 bits (1030), Expect = e-111 Identities = 246/633 (38%), Positives = 343/633 (54%), Gaps = 48/633 (7%) Query: 39 MPRVRYYAGDERRALSFFHQKGLQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVPRLK 98 +PR +G+ + F Q G+QDF TL L+ LYVGAREA+ A ++ L+ Sbjct: 28 VPRKTVSSGELATVVRRFSQTGIQDFLTLTLTEPTGLLYVGAREALFAFSME---ALELQ 84 Query: 99 NMIPWPASDRKKSECAFKKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQD 158 I W A KK+EC K K+N+T+CFNFIR L YN +HLY CGT+AF P CT++ + Sbjct: 85 GAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPYNASHLYVCGTYAFQPKCTYVNM-- 142 Query: 159 SYLLPISEDKVMEGKGQSPFDPAHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVL 218 + + +GKG+ P+DPA H +LVDG LYS T+NNFLG+EPI++R +G + Sbjct: 143 -LTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSATLNNFLGTEPIILRNMGPHHSM 201 Query: 219 KTDNFLRWLHHDASFV--AAIPST--------QVVYFFFEETASEFDFFERLHTSRVARV 268 KT+ WL ++ FV A +P + VYFFF E A E D + +RVARV Sbjct: 202 KTEYLAFWL-NEPHFVGSAYVPESVGSFTGDDDKVYFFFRERAVESDCYAEQVVARVARV 260 Query: 269 CKNDVGGEKLLQKKWTTFLKAQLLCTQPG-QLPFNVIRHAVLLPADSPTAPHIYAVFTSQ 327 CK D+GG + LQ+KWTTFLKA+L C+ P QL FN ++ L S + VF +Q Sbjct: 261 CKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAMHTLQDTSWHNTTFFGVFQAQ 320 Query: 328 WQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYRGPETNPRPGSC-------- 379 W G SA+C + L +I+RVF+G YKE ++E +W Y P +PRPGSC Sbjct: 321 W--GDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTDPVPSPRPGSCINNWHRRH 378 Query: 380 ---SVGPSSDKALTFMKDHFLMDEQV---VGTPLLVKSGVEYTRLAVETAQGLDGHSHLV 433 S D L F+K H LM+EQV PLLVK G +T L + GLDG ++ V Sbjct: 379 GYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNFTHLVADRVTGLDGATYTV 438 Query: 434 MYLGTTTGSLHKAVVSGDSSAHLVEEIQLFPDPEPVRNLQLAPTQGAVFVGFSGGVWRVP 493 +++GT G L KAV G HL+EE+QLF D EP+R+L L+ ++ +F G + ++P Sbjct: 439 LFIGTGDGWLLKAVSLG-PWVHLIEELQLF-DQEPMRSLVLSQSKKLLFAGSRSQLVQLP 496 Query: 494 RANCSVYESCVDCVLARDPHCAWDPESRTCCLLSAPNLNSWKQDMERGNPEWACASGPMS 553 A+C Y SC DCVLARDP+CAW + C + + + Q + + C + S Sbjct: 497 VADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQHVMTSDTSGIC-NLRGS 555 Query: 554 RSLRPQSRPQIIKEVLAVPNSILELPCPHLSALASYYWSHGPAAVP--EASSTVYNGSLL 611 + +RP K + V + L LPC S LA W+ G +P + S +Y+ L Sbjct: 556 KKVRPTP-----KNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQPGSFLYDARLQ 610 Query: 612 LIV----QDGVGGLYQCWATENGFSYPVISYWV 640 +V Q G Y C++ E G Y V Sbjct: 611 ALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLV 643 >gi|214010218 semaphorin 4D isoform 1 [Homo sapiens] Length = 862 Score = 385 bits (988), Expect = e-106 Identities = 243/629 (38%), Positives = 340/629 (54%), Gaps = 64/629 (10%) Query: 38 PMPRVRYYAGDERRALSF--FHQKGLQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVP 95 P+PR+ + E R + FH+ + ++ LLLS D +TLY+GAREA+ A++ + + Sbjct: 26 PIPRITW----EHREVHLVQFHEPDIYNYSALLLSEDKDTLYIGAREAVFAVNALN--IS 79 Query: 96 RLKNMIPWPASDRKKSECAFKKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIE 155 ++ + W S+ KK++CA K KS +T+C N+IRVL + T LY CGT AF PAC + Sbjct: 80 EKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSATSLYVCGTNAFQPACDHLN 139 Query: 156 LQDSYLLPISEDKVMEGKGQSPFDPAHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQ 215 L L +ED GKG+ PFDPAH +T+V+VDG LYSGT NFLGSEPI+ R Sbjct: 140 LTSFKFLGKNED----GKGRCPFDPAHSYTSVMVDGELYSGTSYNFLGSEPIISRNSSHS 195 Query: 216 PVLKTDNFLRWLHHDASFVAA-----IPST-----QVVYFFFEETASEFDFFERLHTSRV 265 P L+T+ + WL+ + SFV A P + VYFFF E + E++F R+ R+ Sbjct: 196 P-LRTEYAIPWLN-EPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSVEYEFVFRVLIPRI 253 Query: 266 ARVCKNDVGGEKLLQKKWTTFLKAQLLCTQPGQ-LPFNVIRHAVLLPADSPTAPHIYAVF 324 ARVCK D GG + LQKKWT+FLKA+L+C++P L FNV+R +L + P YA+F Sbjct: 254 ARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLRSPGLKVPVFYALF 313 Query: 325 TSQWQVGGTRSSAVCAFSLLDIERVFK-GKYKE---LNKETSRWTTYRGPETNPRPGSCS 380 T Q+ SAVCA++L E VF GKY + + + ++W Y GP PRPG+C Sbjct: 314 TP--QLNNVGLSAVCAYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNGPVPKPRPGACI 371 Query: 381 VGPS-----------SDKALTFMKDHFLMDEQVV---GTPLLVKSGVEYTRLAVETAQGL 426 + DK L F+KDH LMD+ V P L+K V YT++ V+ Q L Sbjct: 372 DSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNYTQIVVDRTQAL 431 Query: 427 DGHSHLVMYLGTTTGSLHKAVVSGDSSAHLVEEIQLFPDPEPVRNLQLAPTQG--AVFVG 484 DG + VM++ T G+LHKA +S + + H++EE QLF D EPV+ L L+ +G V+ G Sbjct: 432 DGTVYDVMFVSTDRGALHKA-ISLEHAVHIIEETQLFQDFEPVQTLLLSSKKGNRFVYAG 490 Query: 485 FSGGVWRVPRANCSVYESCVDCVLARDPHCAWDPESRTCCLLSAPNLNSWKQDMERGNPE 544 + GV + P A C + +C DCVLARDP+CAW P + TC L S E Sbjct: 491 SNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSRGLIQEMSGDA 550 Query: 545 WACASGPMSRSLRPQSRPQIIKEVLAVPNSILELPCPHLSALASYYWSHGPAAVPEASST 604 C P ++ EL C S LA +W V +A S Sbjct: 551 SVC----------PDKSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKF-QNGVLKAESP 599 Query: 605 VY-----NGSLLLIVQDGVGGLYQCWATE 628 Y L+ + +G G+YQC + E Sbjct: 600 KYGLMGRKNLLIFNLSEGDSGVYQCLSEE 628 >gi|214010220 semaphorin 4D isoform 2 [Homo sapiens] Length = 738 Score = 376 bits (965), Expect = e-104 Identities = 221/522 (42%), Positives = 309/522 (59%), Gaps = 48/522 (9%) Query: 38 PMPRVRYYAGDERRALSF--FHQKGLQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVP 95 P+PR+ + E R + FH+ + ++ LLLS D +TLY+GAREA+ A++ + + Sbjct: 26 PIPRITW----EHREVHLVQFHEPDIYNYSALLLSEDKDTLYIGAREAVFAVNALN--IS 79 Query: 96 RLKNMIPWPASDRKKSECAFKKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIE 155 ++ + W S+ KK++CA K KS +T+C N+IRVL + T LY CGT AF PAC + Sbjct: 80 EKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSATSLYVCGTNAFQPACDHLN 139 Query: 156 LQDSYLLPISEDKVMEGKGQSPFDPAHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQ 215 L L +ED GKG+ PFDPAH +T+V+VDG LYSGT NFLGSEPI+ R Sbjct: 140 LTSFKFLGKNED----GKGRCPFDPAHSYTSVMVDGELYSGTSYNFLGSEPIISRNSSHS 195 Query: 216 PVLKTDNFLRWLHHDASFVAA-----IPST-----QVVYFFFEETASEFDFFERLHTSRV 265 P L+T+ + WL+ + SFV A P + VYFFF E + E++F R+ R+ Sbjct: 196 P-LRTEYAIPWLN-EPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSVEYEFVFRVLIPRI 253 Query: 266 ARVCKNDVGGEKLLQKKWTTFLKAQLLCTQPGQ-LPFNVIRHAVLLPADSPTAPHIYAVF 324 ARVCK D GG + LQKKWT+FLKA+L+C++P L FNV+R +L + P YA+F Sbjct: 254 ARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLRSPGLKVPVFYALF 313 Query: 325 TSQWQVGGTRSSAVCAFSLLDIERVFK-GKYKE---LNKETSRWTTYRGPETNPRPGSCS 380 T Q+ SAVCA++L E VF GKY + + + ++W Y GP PRPG+C Sbjct: 314 TP--QLNNVGLSAVCAYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNGPVPKPRPGACI 371 Query: 381 VGPS-----------SDKALTFMKDHFLMDEQVV---GTPLLVKSGVEYTRLAVETAQGL 426 + DK L F+KDH LMD+ V P L+K V YT++ V+ Q L Sbjct: 372 DSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNYTQIVVDRTQAL 431 Query: 427 DGHSHLVMYLGTTTGSLHKAVVSGDSSAHLVEEIQLFPDPEPVRNLQLAPTQG--AVFVG 484 DG + VM++ T G+LHKA +S + + H++EE QLF D EPV+ L L+ +G V+ G Sbjct: 432 DGTVYDVMFVSTDRGALHKA-ISLEHAVHIIEETQLFQDFEPVQTLLLSSKKGNRFVYAG 490 Query: 485 FSGGVWRVPRANCSVYESCVDCVLARDPHCAWDPESRTCCLL 526 + GV + P A C + +C DCVLARDP+CAW P + TC L Sbjct: 491 SNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVAL 532 >gi|28872814 semaphorin 4G [Homo sapiens] Length = 843 Score = 341 bits (874), Expect = 2e-93 Identities = 247/692 (35%), Positives = 344/692 (49%), Gaps = 80/692 (11%) Query: 57 HQKG-LQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVPRLKNMIPWPASDRKKSECAF 115 H KG Q++ TLLL L VGAR A+ +L D G K I W AS +S+C Sbjct: 48 HFKGQAQNYSTLLLEEASARLLVGARGALFSLSANDIGDGAHKE-IHWEASPEMQSKCHQ 106 Query: 116 KKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQ 175 K K+N+T+CFN +R L N THLY CGT AF P C I+ + ++ LP S + EGK + Sbjct: 107 KGKNNQTECFNHVRFLQRLNSTHLYACGTHAFQPLCAAIDAE-AFTLPTSFE---EGKEK 162 Query: 176 SPFDPAHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNFLRWLHHDASFV- 234 P+DPA T +++DG LY+ T F S P + R+ + + + WL+ DA FV Sbjct: 163 CPYDPARGFTGLIIDGGLYTATRYEFR-SIPDIRRSRHPHSLRTEETPMHWLN-DAEFVF 220 Query: 235 ---------AAIPSTQVVYFFFEETASE-----FDFFERLH-TSRVARVCKNDVGGEKLL 279 +A+ VY+FF E A+E F H +RVARVCK D+GG+K+L Sbjct: 221 SVLVRESKASAVGDDDKVYYFFTERATEEGSGSFTQSRSSHRVARVARVCKGDLGGKKIL 280 Query: 280 QKKWTTFLKAQLLCTQPGQLPFNVIRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVC 339 QKKWT+FLKA+L+C P + +R L A++ + H YA FT Q +SA+C Sbjct: 281 QKKWTSFLKARLICHIP---LYETLRGVCSLDAETSSRTHFYAAFTLSTQWKTLEASAIC 337 Query: 340 AFSLLDIERVFKGKYKELNKETSRWTTYRGPETNPRPGSC------SVGPSSDK-----A 388 + L +I+ VF G Y E + RW Y G PRPGSC S G +S + Sbjct: 338 RYDLAEIQAVFAGPYMEYQDGSRRWGRYEGGVPEPRPGSCITDSLRSQGYNSSQDLPSLV 397 Query: 389 LTFMKDHFLMDEQVV---GTPLLVKSGVEYTRLAVETAQGLDGHSHLVMYLGTTTGSLHK 445 L F+K H LM VV G PLL+K + YT L G ++ +++LGT G +HK Sbjct: 398 LDFVKLHPLMARPVVPTRGRPLLLKRNIRYTHLTGTPVTTPAGPTYDLLFLGTADGWIHK 457 Query: 446 AVVSGDSSAHLVEEIQLFPDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESCVD 505 AVV G S H++EE Q+F + + V NL ++ Q +++VG GV ++P ++CS Y SC D Sbjct: 458 AVVLG-SGMHIIEETQVFRESQSVENLVISLLQHSLYVGAPSGVIQLPLSSCSRYRSCYD 516 Query: 506 CVLARDPHCAWDPESRTCCLL------SAPNLNSWKQDMERGNPEWACASGPMSRSLRPQ 559 C+LARDP+C WDP + C S + + QD+ERGN C S SR P Sbjct: 517 CILARDPYCGWDPGTHACAAATTIANRSQGSRTALIQDIERGNR--GCES---SRDTGP- 570 Query: 560 SRPQIIKEVLAVPNSILELPCPHLSALASYYW----SHGPAAVPEASSTVYNGSLLLIVQ 615 P +K + + LPC S LA W S G + +G L+ Q Sbjct: 571 --PPPLKTRSVLRGDDVLLPCDQPSNLARALWLLNGSMGLSDGQGGYRVGVDGLLVTDAQ 628 Query: 616 DGVGGLYQCWATENGFSYPVISYWVDSQDQTLALDPELAGIPREHVKVPLTRVSGGAALA 675 G Y C+A ENG + SY + + T A P+ P GA LA Sbjct: 629 PEHSGNYGCYAEENGLRTLLASYSLTVRPATPAPAPKAPATP-------------GAQLA 675 Query: 676 AQQSYWPHFVTVTVLFALVLSGALIILVASPL 707 V + + A+ G L +++AS L Sbjct: 676 PD-------VRLLYVLAIAALGGLCLILASSL 700 >gi|19923279 semaphorin W [Homo sapiens] Length = 770 Score = 337 bits (865), Expect = 2e-92 Identities = 230/658 (34%), Positives = 328/658 (49%), Gaps = 58/658 (8%) Query: 19 FQLLQLLLPTTTAGGGGQGPMPRVRYYAGDERRALSFFHQKGLQDFDTLLLSGDGNTLYV 78 F LL L + + G +PR + L+ F ++ LL+ +TLYV Sbjct: 20 FPLLLLAVLSGPVSGRVPRSVPRTSLPISEADSCLTRFAVPHTYNYSVLLVDPASHTLYV 79 Query: 79 GAREAILALDIQDPGV-PRLKNMIPWPASDRKKSECAFKKKSNETQCFNFIRVLVSYNVT 137 GAR+ I AL + G PR I W + + C KK E +C NF+++L N + Sbjct: 80 GARDTIFALSLPFSGERPR---RIDWMVPEAHRQNCR-KKGKKEDECHNFVQILAIANAS 135 Query: 138 HLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDPAHKHTAVLVDGMLYSGT 197 HL TCGTFAF P C I++ + +++ G+G+ PF+PA + AV+ G+LY+ T Sbjct: 136 HLLTCGTFAFDPKCGVIDVSRFQQV----ERLESGRGKCPFEPAQRSAAVMAGGVLYAAT 191 Query: 198 MNNFLGSEPILMRTLG-SQPVLKTDNFLRWLHHDASFVAAIPSTQV----------VYFF 246 + N+LG+EPI+ R +G ++ ++TD WL+ A FVAA+ + +YFF Sbjct: 192 VKNYLGTEPIITRAVGRAEDWIRTDTLPSWLNAPA-FVAAVALSPAEWGDEDGDDEIYFF 250 Query: 247 FEETASEFDFFERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCTQP--GQLPFNVI 304 F ET+ FD +ER+ RVARVC D+GG K LQ++WTTFLKA LLC P G+ + Sbjct: 251 FTETSRAFDSYERIKVPRVARVCAGDLGGRKTLQQRWTTFLKADLLCPGPEHGRASSVLQ 310 Query: 305 RHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRW 364 AVL P P Y +F+SQW+ G SAVCAF DI V G ++EL + +R Sbjct: 311 DVAVLRPELGAGTPIFYGIFSSQWE--GATISAVCAFRPQDIRTVLNGPFRELKHDCNRG 368 Query: 365 TTYRGPET-NPRPGSC--------SVGPS---SDKALTFMKDHFLMDEQVV---GTPLLV 409 + PRPG C G S D+ LTF++DH LMD V G PLLV Sbjct: 369 LPVVDNDVPQPRPGECITNNMKLRHFGSSLSLPDRVLTFIRDHPLMDRPVFPADGHPLLV 428 Query: 410 KSGVEYTRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSAHLVEEIQLFPDPEPV 469 + Y R+ L G + V+YLGT G LH+AV G + ++E++ LFP+P+PV Sbjct: 429 TTDTAYLRVVAHRVTSLSGKEYDVLYLGTEDGHLHRAVRIG-AQLSVLEDLALFPEPQPV 487 Query: 470 RNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESCVDCVLARDPHCAWDPESRTCCLLSAP 529 N++L + VG V +V NC +SC +C+LA+DP CAW C+ A Sbjct: 488 ENMKL--YHSWLLVGSRTEVTQVNTTNCGRLQSCSECILAQDPVCAWSFRLDE-CVAHAG 544 Query: 530 NLNSWKQDMERGNPEWACASGPMSRSLRPQSRPQIIKEVLAVPNSILELPCPHLSALASY 589 QD+E + C P R ++ EV + + LPC SA AS Sbjct: 545 EHRGLVQDIESADVSSLCPKEPGER--------PVVFEVPVATAAHVVLPCSPSSAWASC 596 Query: 590 YWSHGPAAVPEASSTVYNGSLLLIVQDGVGGLYQCWATENGFSYPVISY---WVDSQD 644 W H P+ V + T L ++V G G Y C E G ++ V +Y W +D Sbjct: 597 VW-HQPSGV--TALTPRRDGLEVVVTPGAMGAYACECQEGGAAHVVAAYSLVWGSQRD 651 >gi|5174673 semaphorin 3A precursor [Homo sapiens] Length = 771 Score = 301 bits (771), Expect = 1e-81 Identities = 199/629 (31%), Positives = 310/629 (49%), Gaps = 58/629 (9%) Query: 48 DERRALSFFHQKGLQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVPRLKNM--IPWPA 105 + ++F + T LL + + LYVGA++ I + D+ + +K+ I WP Sbjct: 41 ESNNVITFNGLANSSSYHTFLLDEERSRLYVGAKDHIFSFDLVN-----IKDFQKIVWPV 95 Query: 106 SDRKKSECAFKKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIEL---QDSYLL 162 S ++ EC + K +C NFI+VL +YN THLY CGT AF P CT+IE+ + + Sbjct: 96 SYTRRDECKWAGKDILKECANFIKVLKAYNQTHLYACGTGAFHPICTYIEIGHHPEDNIF 155 Query: 163 PISEDKVMEGKGQSPFDPAHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDN 222 + G+G+SP+DP ++L+DG LYSGT +F+G + + RTLG ++T+ Sbjct: 156 KLENSHFENGRGKSPYDPKLLTASLLIDGELYSGTAADFMGRDFAIFRTLGHHHPIRTEQ 215 Query: 223 F-LRWLHHDASFVAA-------IPSTQVVYFFFEETASEFDFFERLHTSRVARVCKNDVG 274 RWL +D F++A P VYFFF E A + + + +R+ ++CKND G Sbjct: 216 HDSRWL-NDPKFISAHLISESDNPEDDKVYFFFRENAIDGEHSGKATHARIGQICKNDFG 274 Query: 275 GEKLLQKKWTTFLKAQLLCTQPG----QLPFNVIRHAVLLPADSPTAPHIYAVFTSQWQV 330 G + L KWTTFLKA+L+C+ PG F+ ++ L+ P P +Y VFT+ + Sbjct: 275 GHRSLVNKWTTFLKARLICSVPGPNGIDTHFDELQDVFLMNFKDPKNPVVYGVFTTSSNI 334 Query: 331 GGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYRGPETNPRPGSC---------SV 381 + SAVC +S+ D+ RVF G Y + +W Y+G PRPG+C S Sbjct: 335 --FKGSAVCMYSMSDVRRVFLGPYAHRDGPNYQWVPYQGRVPYPRPGTCPSKTFGGFDST 392 Query: 382 GPSSDKALTFMKDHFLMDEQVV---GTPLLVKSGVEY--TRLAVETAQGLDGHSHLVMYL 436 D +TF + H M V P+++K+ V Y T++ V+ DG + VM++ Sbjct: 393 KDLPDDVITFARSHPAMYNPVFPMNNRPIVIKTDVNYQFTQIVVDRVDAEDG-QYDVMFI 451 Query: 437 GTTTGSLHKAV-----VSGDSSAHLVEEIQLFPDPEPVRNLQLAPTQGAVFVGFSGGVWR 491 GT G++ K V D L+EE+ +F +P + ++L+ Q +++G + GV + Sbjct: 452 GTDVGTVLKVVSIPKETWYDLEEVLLEEMTVFREPTAISAMELSTKQQQLYIGSTAGVAQ 511 Query: 492 VPRANCSVY-ESCVDCVLARDPHCAWDPESRTCCLLSAPNLNSWKQDMERGNPEWACASG 550 +P C +Y ++C +C LARDP+CAWD + + +A + +QD+ G+P C+ Sbjct: 512 LPLHRCDIYGKACAECCLARDPYCAWDGSACSRYFPTAKR-RTRRQDIRNGDPLTHCSDL 570 Query: 551 PMSRSLRPQSRPQIIKEVLAVPNSILELPCPHLSALASYYWS--------HGPAAVPEAS 602 +II V NS L C S A YW V + Sbjct: 571 HHDNHHGHSPEERII---YGVENSSTFLECSPKSQRALVYWQFQRRNEERKEEIRVDDHI 627 Query: 603 STVYNGSLLLIVQDGVGGLYQCWATENGF 631 G LL +Q G Y C A E+GF Sbjct: 628 IRTDQGLLLRSLQQKDSGNYLCHAVEHGF 656 >gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens] Length = 749 Score = 298 bits (763), Expect = 1e-80 Identities = 201/651 (30%), Positives = 319/651 (49%), Gaps = 62/651 (9%) Query: 32 GGGGQGPMP---RVRYYAGDERRALSFFHQKGLQDFDTLLLSGDGNTLYVGAREAILALD 88 G G P P R+ + L F + + LL+ + L+VGA + +L+ Sbjct: 20 GLGSAAPSPPRLRLSFQELQAWHGLQTFSLERTCCYQALLVDEERGRLFVGAENHVASLN 79 Query: 89 IQDPGVPRLKNMIPWPASDRKKSECAFKKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFS 148 + + + + + WPA + EC + K T+C NF+++L +YN THL CGT AF Sbjct: 80 LDN--ISKRAKKLAWPAPVEWREECNWAGKDIGTECMNFVKLLHAYNRTHLLACGTGAFH 137 Query: 149 PACTFIEL---QDSYLLPISEDKVMEGKGQSPFDPAHKHTAVLVDGMLYSGTMNNFLGSE 205 P C F+E+ + +L + ++ +GKG+SP+DP H+ +VLV LYSG + +G + Sbjct: 138 PTCAFVEVGHRAEEPVLRLDPGRIEDGKGKSPYDPRHRAASVLVGEELYSGVAADLMGRD 197 Query: 206 PILMRTLGSQPVLKTD-NFLRWLHHDASFVAAI-------PSTQVVYFFFEETASEF-DF 256 + R+LG +P L+T+ + RWL+ + FV P +YFFF ETA E Sbjct: 198 FTIFRSLGQRPSLRTEPHDSRWLN-EPKFVKVFWIPESENPDDDKIYFFFRETAVEAAPA 256 Query: 257 FERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCTQP---GQLPFNVIRHAVLLPAD 313 RL SRV ++C+NDVGG++ L KWTTFLKA+L+C+ P G F+ ++ LL + Sbjct: 257 LGRLSVSRVGQICRNDVGGQRSLVNKWTTFLKARLVCSVPGVEGDTHFDQLQDVFLLSSR 316 Query: 314 SPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYRGPETN 373 P +YAVF++ + + SAVC +S+ D+ R F G + +W +Y+G Sbjct: 317 DHRTPLLYAVFSTSSSI--FQGSAVCVYSMNDVRRAFLGPFAHKEGPMHQWVSYQGRVPY 374 Query: 374 PRPGSC---------SVGPSSDKALTFMKDHFLMDEQVV---GTPLLVKSGVEY--TRLA 419 PRPG C S D + F ++H LM V+ G PL ++ G Y T++A Sbjct: 375 PRPGMCPSKTFGTFSSTKDFPDDVIQFARNHPLMYNSVLPTGGRPLFLQVGANYTFTQIA 434 Query: 420 VETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSS-----AHLVEEIQLFPDPEPVRNLQL 474 + DGH + V+++GT G++ K + S L+EE+ +F D V ++Q+ Sbjct: 435 ADRVAAADGH-YDVLFIGTDVGTVLKVISVPKGSRPSAEGLLLEELHVFEDSAAVTSMQI 493 Query: 475 APTQGAVFVGFSGGVWRVPRANCSVY-ESCVDCVLARDPHCAWDPESRTCCLLSAPNLNS 533 + + ++V V ++ C+ + C +C LARDP+CAWD + T SA Sbjct: 494 SSKRHQLYVASRSAVAQIALHRCAAHGRVCTECCLARDPYCAWDGVACTRFQPSAKR-RF 552 Query: 534 WKQDMERGNPEWACASGPMSRSLRPQSRPQIIK-EVLAVPNSILELPCPHLSALASYYW- 591 +QD+ G+P C+ SRP +++ +V V S L C S A W Sbjct: 553 RRQDVRNGDPSTLCSG--------DSSRPALLEHKVFGVEGSSAFLECEPRSLQARVEWT 604 Query: 592 -------SHGPAAVPEASSTVYNGSLLLIVQDGVGGLYQCWATENGFSYPV 635 +H E + G LL ++ G+Y C A E GF+ P+ Sbjct: 605 FQRAGVTAHTQVLAEERTERTARGLLLRRLRRRDSGVYLCAAVEQGFTQPL 655 >gi|54607089 semaphorin 3B isoform 2 precursor [Homo sapiens] Length = 748 Score = 297 bits (760), Expect = 3e-80 Identities = 202/651 (31%), Positives = 318/651 (48%), Gaps = 63/651 (9%) Query: 32 GGGGQGPMP---RVRYYAGDERRALSFFHQKGLQDFDTLLLSGDGNTLYVGAREAILALD 88 G G P P R+ + L F + + LL+ + L+VGA + +L+ Sbjct: 20 GLGSAAPSPPRLRLSFQELQAWHGLQTFSLERTCCYQALLVDEERGRLFVGAENHVASLN 79 Query: 89 IQDPGVPRLKNMIPWPASDRKKSECAFKKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFS 148 + + + + + WPA + EC + K T+C NF+++L +YN THL CGT AF Sbjct: 80 LDN--ISKRAKKLAWPAPVEWREECNWAGKDIGTECMNFVKLLHAYNRTHLLACGTGAFH 137 Query: 149 PACTFIEL---QDSYLLPISEDKVMEGKGQSPFDPAHKHTAVLVDGMLYSGTMNNFLGSE 205 P C F+E+ + +L + ++ +GKG+SP+DP H+ +VLV LYSG + +G + Sbjct: 138 PTCAFVEVGHRAEEPVLRLDPGRIEDGKGKSPYDPRHRAASVLVGEELYSGVAADLMGRD 197 Query: 206 PILMRTLGSQPVLKTD-NFLRWLHHDASFVAAI-------PSTQVVYFFFEETASEF-DF 256 + R+LG +P L+T+ + RWL+ + FV P +YFFF ETA E Sbjct: 198 FTIFRSLGQRPSLRTEPHDSRWLN-EPKFVKVFWIPESENPDDDKIYFFFRETAVEAAPA 256 Query: 257 FERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCTQP---GQLPFNVIRHAVLLPAD 313 RL SRV ++C+NDVGG++ L KWTTFLKA+L+C+ P G F+ ++ LL + Sbjct: 257 LGRLSVSRVGQICRNDVGGQRSLVNKWTTFLKARLVCSVPGVEGDTHFDQLQDVFLLSSR 316 Query: 314 SPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYRGPETN 373 P +YAVF++ G SAVC +S+ D+ R F G + +W +Y+G Sbjct: 317 DHRTPLLYAVFSTSSIFQG---SAVCVYSMNDVRRAFLGPFAHKEGPMHQWVSYQGRVPY 373 Query: 374 PRPGSC---------SVGPSSDKALTFMKDHFLMDEQVV---GTPLLVKSGVEY--TRLA 419 PRPG C S D + F ++H LM V+ G PL ++ G Y T++A Sbjct: 374 PRPGMCPSKTFGTFSSTKDFPDDVIQFARNHPLMYNSVLPTGGRPLFLQVGANYTFTQIA 433 Query: 420 VETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSS-----AHLVEEIQLFPDPEPVRNLQL 474 + DGH + V+++GT G++ K + S L+EE+ +F D V ++Q+ Sbjct: 434 ADRVAAADGH-YDVLFIGTDVGTVLKVISVPKGSRPSAEGLLLEELHVFEDSAAVTSMQI 492 Query: 475 APTQGAVFVGFSGGVWRVPRANCSVY-ESCVDCVLARDPHCAWDPESRTCCLLSAPNLNS 533 + + ++V V ++ C+ + C +C LARDP+CAWD + T SA Sbjct: 493 SSKRHQLYVASRSAVAQIALHRCAAHGRVCTECCLARDPYCAWDGVACTRFQPSAKR-RF 551 Query: 534 WKQDMERGNPEWACASGPMSRSLRPQSRPQIIK-EVLAVPNSILELPCPHLSALASYYW- 591 +QD+ G+P C+ SRP +++ +V V S L C S A W Sbjct: 552 RRQDVRNGDPSTLCSG--------DSSRPALLEHKVFGVEGSSAFLECEPRSLQARVEWT 603 Query: 592 -------SHGPAAVPEASSTVYNGSLLLIVQDGVGGLYQCWATENGFSYPV 635 +H E + G LL ++ G+Y C A E GF+ P+ Sbjct: 604 FQRAGVTAHTQVLAEERTERTARGLLLRRLRRRDSGVYLCAAVEQGFTQPL 654 >gi|188497703 semaphorin 3F [Homo sapiens] Length = 785 Score = 291 bits (744), Expect = 2e-78 Identities = 201/649 (30%), Positives = 311/649 (47%), Gaps = 91/649 (14%) Query: 63 DFDTLLLSGDGNTLYVGAREAILALDIQDPGVPRLKNMIPWPASDRKKSECAFKKKSNET 122 D+ LL D + +YVG+++ +L+LD+ D + R +I W AS ++ EC K Sbjct: 56 DYRILLKDEDHDRMYVGSKDYVLSLDLHD--INREPLIIHWAASPQRIEECVLSGKDVNG 113 Query: 123 QCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIEL-------------------------- 156 +C NF+R++ +N THLY CGT A++P CT++ Sbjct: 114 ECGNFVRLIQPWNRTHLYVCGTGAYNPMCTYVNRGRRAQATPWTQTQAVRGRGSRATDGA 173 Query: 157 --------QDSYLLPISEDKVMEGKGQSPFDPAHKHTAVLVDGMLYSGTMNNFLGSEPIL 208 + Y+ + +++ GKG+ P+DP + L++ LY+G +F+G++ + Sbjct: 174 LRPMPTAPRQDYIFYLEPERLESGKGKCPYDPKLDTASALINEELYAGVYIDFMGTDAAI 233 Query: 209 MRTLGSQPVLKTDNF-LRWLHHDASFVAA--IPST-----QVVYFFFEETASEFDFFERL 260 RTLG Q ++TD + RWL +D SF+ A IP + +YFFF E ++E + Sbjct: 234 FRTLGKQTAMRTDQYNSRWL-NDPSFIHAELIPDSAERNDDKLYFFFRERSAEAPQSPAV 292 Query: 261 HTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCTQPG----QLPFNVIRHAVLLPADSPT 316 + +R+ R+C ND GG L KW+TFLKA+L+C+ PG + F+ ++ + Sbjct: 293 Y-ARIGRICLNDDGGHCCLVNKWSTFLKARLVCSVPGEDGIETHFDELQDVFVQQTQDVR 351 Query: 317 APHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYRGPETNPRP 376 P IYAVFTS V R SAVC +S+ DI VF G + +W + G PRP Sbjct: 352 NPVIYAVFTSSGSV--FRGSAVCVYSMADIRMVFNGPFAHKEGPNYQWMPFSGKMPYPRP 409 Query: 377 GSCSVG---PS-------SDKALTFMKDHFLMDEQVV---GTPLLVKSGVEY--TRLAVE 421 G+C G PS D+ + FM+ H LM + V PL+V++G Y T +AV+ Sbjct: 410 GTCPGGTFTPSMKSTKDYPDEVINFMRSHPLMYQAVYPLQRRPLVVRTGAPYRLTTIAVD 469 Query: 422 TAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSAHL----VEEIQLFPDPEPVRNLQLAPT 477 DG + V++LGT G++ K +V L +EE+++F DP PV+ + ++ Sbjct: 470 QVDAADGR-YEVLFLGTDRGTVQKVIVLPKDDQELEELMLEEVEVFKDPAPVKTMTISSK 528 Query: 478 QGAVFVGFSGGVWRVPRANCSVY-ESCVDCVLARDPHCAWDPESRTCCLLSAPN-LNSWK 535 + ++V + GV + C Y +C DC LARDP+CAWD + C +A + S + Sbjct: 529 RQQLYVASAVGVTHLSLHRCQAYGAACADCCLARDPYCAWD--GQACSRYTASSKRRSRR 586 Query: 536 QDMERGNPEWACASGPMSRSLRPQSRPQIIKEV-LAVPNSILELPCPHLSALASYYW--- 591 QD+ GNP C R + ++ V V S L C S A+ W Sbjct: 587 QDVRHGNPIRQC------RGFNSNANKNAVESVQYGVAGSAAFLECQPRSPQATVKWLFQ 640 Query: 592 -----SHGPAAVPEASSTVYNGSLLLIVQDGVGGLYQCWATENGFSYPV 635 + G LL +Q GLY C ATEN F + V Sbjct: 641 RDPGDRRREIRAEDRFLRTEQGLLLRALQLSDRGLYSCTATENNFKHVV 689 >gi|41406086 semaphorin 3D [Homo sapiens] Length = 777 Score = 288 bits (737), Expect = 1e-77 Identities = 207/672 (30%), Positives = 320/672 (47%), Gaps = 67/672 (9%) Query: 16 LFLFQLLQLLLPTTTAGGGGQGPMPRVRYYAGD---ERRALSFFHQKGLQDFDTLLLSGD 72 L + + L LP T G + +PR++ D + F DF TLLL + Sbjct: 22 LMMLSMTMLFLPVT---GTLKQNIPRLKLTYKDLLLSNSCIPFLGSSEGLDFQTLLLDEE 78 Query: 73 GNTLYVGAREAILALDIQDPGVPRLKNMIPWPASDRKKSECAFKKKSNETQCFNFIRVLV 132 L +GA++ I L + D + + I WPA+ + C K T+C NFIRVL Sbjct: 79 RGRLLLGAKDHIFLLSLVD--LNKNFKKIYWPAAKERVELCKLAGKDANTECANFIRVLQ 136 Query: 133 SYNVTHLYTCGTFAFSPACTFIEL---QDSYLLPISEDKVMEGKGQSPFDPAHKHTAVLV 189 YN TH+Y CGT AF P C +I+L ++ + + + G+ + PFDP +V+ Sbjct: 137 PYNKTHIYVCGTGAFHPICGYIDLGVYKEDIIFKLDTHNLESGRLKCPFDPQQPFASVMT 196 Query: 190 DGMLYSGTMNNFLGSEPILMRTLG---SQPVLKTDNFLRWLHHDASFVAAI-------PS 239 D LYSGT ++FLG + R+LG ++TD + + A F+ P Sbjct: 197 DEYLYSGTASDFLGKDTAFTRSLGPTHDHHYIRTDISEHYWLNGAKFIGTFFIPDTYNPD 256 Query: 240 TQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCTQPG-- 297 +YFFF E++ E ++ SRV RVCKNDVGG++ L KWTTFLKA+L+C+ PG Sbjct: 257 DDKIYFFFRESSQEGSTSDKTILSRVGRVCKNDVGGQRSLINKWTTFLKARLICSIPGSD 316 Query: 298 --QLPFNVIRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYK 355 F+ ++ LLP P +Y VFT+ + + SAVC +S+ DI VF G Y Sbjct: 317 GADTYFDELQDIYLLPTRDERNPVVYGVFTTTSSI--FKGSAVCVYSMADIRAVFNGPYA 374 Query: 356 ELNKETSRWTTYRGPETNPRPGSC----------SVGPSSDKALTFMKDHFLMDEQ---V 402 RW Y G PRPG+C S D ++F+K H +M + V Sbjct: 375 HKESADHRWVQYDGRIPYPRPGTCPSKTYDPLIKSTRDFPDDVISFIKRHSVMYKSVYPV 434 Query: 403 VGTPLLVKSGVEY--TRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSAHL---- 456 G P + V+Y T++ V+ DG + VM+LGT G++ K V ++ Sbjct: 435 AGGPTFKRINVDYRLTQIVVDHVIAEDG-QYDVMFLGTDIGTVLKVVSISKEKWNMEEVV 493 Query: 457 VEEIQLFPDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVY-ESCVDCVLARDPHCA 515 +EE+Q+F + N++L+ Q +++G G+ ++ C Y ++C DC LARDP+CA Sbjct: 494 LEELQIFKHSSIILNMELSLKQQQLYIGSRDGLVQLSLHRCDTYGKACADCCLARDPYCA 553 Query: 516 WDPESRTCCLLSAP--NLNSWKQDMERGNPEWACASGPMSRSLRPQSRPQIIKEVLAVPN 573 WD + C AP + +QD++ G+P C + S+ ++ + K + + Sbjct: 554 WDGNA---CSRYAPTSKRRARRQDVKYGDPITQC--WDIEDSISHETADE--KVIFGIEF 606 Query: 574 SILELPCPHLSALASYYW-------SHGPAAVPEAS--STVYNGSLLLIVQDGVGGLYQC 624 + L C S A+ W H P+ T Y G L+ +Q G+Y C Sbjct: 607 NSTFLECIPKSQQATIKWYIQRSGDEHREELKPDERIIKTEY-GLLIRSLQKKDSGMYYC 665 Query: 625 WATENGFSYPVI 636 A E+ F + ++ Sbjct: 666 KAQEHTFIHTIV 677 >gi|5454048 semaphorin 3C [Homo sapiens] Length = 751 Score = 282 bits (722), Expect = 7e-76 Identities = 201/648 (31%), Positives = 316/648 (48%), Gaps = 60/648 (9%) Query: 34 GGQGPMPRVRYYAGDERRALSFFHQKGLQ----DFDTLLLSGDGNTLYVGAREAILALDI 89 G P RV Y DE R L D+ LL+ D + +YVG+++ IL+L+I Sbjct: 21 GSSQPQARV-YLTFDELRETKTSEYFSLSHHPLDYRILLMDEDQDRIYVGSKDHILSLNI 79 Query: 90 QDPGVPRLKNMIPWPASDRKKSECAFKKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFSP 149 + L + WPAS K EC K C NF+RV+ ++N THLY CG+ AFSP Sbjct: 80 NNISQEALS--VFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSP 137 Query: 150 ACTFIE--LQDSYLLPISEDKVMEGKGQSPFDPAHKHTAVLVDGMLYSGTMNNFLGSEPI 207 CT++ + + + + K GKG+ F+P +V+++ L+SG +F+G++ Sbjct: 138 VCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAA 197 Query: 208 LMRTLGSQPVLKTDNF-LRWLHH----DASFV--AAIPSTQVVYFFFEETASEFDFFERL 260 + R+L + ++TD +WL DA + P+ VYFFF+E ++ + + Sbjct: 198 IFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQ 257 Query: 261 HTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCT----QPGQLPFNVIRHAVLLPADSPT 316 S +AR+C ND GG + L KWTTFLKA+L+C+ + F+ + LL D+P Sbjct: 258 IHSMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPR 317 Query: 317 APHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYRGPETNPRP 376 +Y +FT+ V + SAVC + L DI+ VF G + + +Y+G PRP Sbjct: 318 TTLVYGIFTTSSSV--FKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRP 375 Query: 377 GSCSVGPSS----------DKALTFMKDHFLMDEQVV---GTPLLVKSGVE--YTRLAVE 421 G+C G + D +TF+++H LM + PL+V+ G + YT++AV+ Sbjct: 376 GTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVD 435 Query: 422 TAQGLDGHSHLVMYLGTTTGSLHKAVV----SGDSSAHLVEEIQLFPDPEPVRNLQLAPT 477 DG H V++LGT G++ K VV + S ++EE+++F + P+ ++++ Sbjct: 436 RVNAADGRYH-VLFLGTDRGTVQKVVVLPTNNSVSGELILEELEVFKNHAPITTMKISSK 494 Query: 478 QGAVFVGFSGGVWRVPRANCSVY-ESCVDCVLARDPHCAWDPESRTCCLLSAP--NLNSW 534 + ++V + GV +V C +Y +C DC LARDP+CAWD S C P S Sbjct: 495 KQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHS---CSRFYPTGKRRSR 551 Query: 535 KQDMERGNPEWACASGPMSRSLRPQSRPQIIKEVLAVPNSILELPCPHLSALASYYW--- 591 +QD+ GNP C + ++ +I++ V N+ L C S AS W Sbjct: 552 RQDVRHGNPLTQCRGFNLKAY---RNAAEIVQ--YGVKNNTTFLECAPKSPQASIKWLLQ 606 Query: 592 ----SHGPAAVPEASSTVYNGSLLLIVQDGVGGLYQCWATENGFSYPV 635 + E G L+ VQ GLY C ATEN F + Sbjct: 607 KDKDRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTI 654 >gi|91982767 semaphorin 5B isoform 1 [Homo sapiens] Length = 1151 Score = 267 bits (682), Expect = 3e-71 Identities = 180/502 (35%), Positives = 273/502 (54%), Gaps = 34/502 (6%) Query: 53 LSFFHQKGLQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVPRLKNMIPWPASDRKKSE 112 +S F G +DF L L GN L VGAR + L + + L W +S+ + Sbjct: 115 VSNFTYPGARDFSQLALDPSGNQLIVGARNYLFRLSLANVS---LLQATEWASSEDTRRS 171 Query: 113 CAFKKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEG 172 C K K+ E +C N++RVL+ ++ CGT AFSP CT ++ + L + +K+ G Sbjct: 172 CQSKGKTEE-ECQNYVRVLIVAG-RKVFMCGTNAFSPMCTSRQVGN---LSRTIEKI-NG 225 Query: 173 KGQSPFDPAHKHTAVLVD-GMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNF-LRWLHHD 230 + P+DP H TAV+ G LY+ T+ +F G +P + R+LGS P L+T + +WL+ + Sbjct: 226 VARCPYDPRHNSTAVISSQGELYAATVIDFSGRDPAIYRSLGSGPPLRTAQYNSKWLN-E 284 Query: 231 ASFVAAIPSTQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQ 290 +FVAA YFF E A E D ++ SRVARVCKNDVGG LL+ WTTF+KA+ Sbjct: 285 PNFVAAYDIGLFAYFFLRENAVEHDCGRTVY-SRVARVCKNDVGGRFLLEDTWTTFMKAR 343 Query: 291 LLCTQPGQLPF--NVIRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIER 348 L C++PG++PF N ++ A LP IY VFT+ V +SAVCAF+L I + Sbjct: 344 LNCSRPGEVPFYYNELQSAFHLPEQD----LIYGVFTT--NVNSIAASAVCAFNLSAISQ 397 Query: 349 VFKGKYKELNKETSRWTTYRGPETNPRPGSC-SVGPS---SDKALTFMKDHFLMDE---Q 401 F G ++ + W P N + G+ GP+ ++++L + FLM E Sbjct: 398 AFNGPFRYQENPRAAWLPIANPIPNFQCGTLPETGPNENLTERSLQDAQRLFLMSEAVQP 457 Query: 402 VVGTPLLVKSGVEYTRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSAH--LVEE 459 V P + + V ++ L V+ Q D H V+Y+GT +G++ KA+ + S H +EE Sbjct: 458 VTPEPCVTQDSVRFSHLVVDLVQAKDTLYH-VLYIGTESGTILKALSTASRSLHGCYLEE 516 Query: 460 IQLFPD--PEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESCVDCVLARDPHCAWD 517 + + P EP+R+L++ + A+FVG GV RVP C+ Y S C+ ARDP+C WD Sbjct: 517 LHVLPPGRREPLRSLRILHSARALFVGLRDGVLRVPLERCAAYRSQGACLGARDPYCGWD 576 Query: 518 PESRTCCLL-SAPNLNSWKQDM 538 + + C L + N++ W Q++ Sbjct: 577 GKQQRCSTLEDSSNMSLWTQNI 598 >gi|9910362 semaphorin sem2 [Homo sapiens] Length = 782 Score = 263 bits (671), Expect = 6e-70 Identities = 199/659 (30%), Positives = 314/659 (47%), Gaps = 65/659 (9%) Query: 33 GGGQGP-----MPRVRYYAGD---ERRALSFFHQKGLQDFDTLLLSGDGNTLYVGAREAI 84 GG GP +PR+R D R+ F +G + + L + L++G +A+ Sbjct: 19 GGSSGPSPGPSVPRLRLSYRDLLSANRSAIFLGPQGSLNLQAMYLDEYRDRLFLGGLDAL 78 Query: 85 LALDIQDPGVPRLKNMIPWPASDRKKSECAFKKKSNETQCFNFIRVLVSYNVTHLYTCGT 144 +L + D P + ++ WP ++ EC K + T+C NF+RVL +N THL CGT Sbjct: 79 YSLRL-DQAWPDPREVL-WPPQPGQREECVRKGRDPLTECANFVRVLQPHNRTHLLACGT 136 Query: 145 FAFSPACTFIEL--QDSYLLPISEDKVMEGKGQSPFDPAHKHTAVLVDGMLYSGTMNNFL 202 AF P C I + + ++L + V G+G+ P +P+ + +DG LY+G +FL Sbjct: 137 GAFQPTCALITVGHRGEHVLHLEPGSVESGRGRCPHEPSRPFASTFIDGELYTGLTADFL 196 Query: 203 GSEPILMRTLGSQPVLKTDNFLRWLHHDASFVAA--IPSTQ-----VVYFFFEETASEFD 255 G E ++ R+ G +P L++D+ LH D FV A IP VYFFF ET D Sbjct: 197 GREAMIFRSGGPRPALRSDSDQSLLH-DPRFVMAARIPENSDQDNDKVYFFFSETVPSPD 255 Query: 256 F-FERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCTQPG----QLPFNVIRHAVLL 310 + SRV RVC ND GG+++L KW+TFLKA+L+C+ PG + F+ + LL Sbjct: 256 GGSNHVTVSRVGRVCVNDAGGQRVLVNKWSTFLKARLVCSVPGPGGAETHFDQLEDVFLL 315 Query: 311 PADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYRGP 370 + + +YA+F++ V + AVC + + DI VF G + + +W Y G Sbjct: 316 WPKAGKSLEVYALFSTVSAV--FQGFAVCVYHMADIWEVFNGPFAHRDGPQHQWGPYGGK 373 Query: 371 ETNPRPGSC-------------SVGPSSDKALTFMKDHFLMDEQV---VGTPLLVKSGV- 413 PRPG C S D+ L F + H LM V G P+LVK+ + Sbjct: 374 VPFPRPGVCPSKMTAQPGRPFGSTKDYPDEVLQFARAHPLMFWPVRPRHGRPVLVKTHLA 433 Query: 414 -EYTRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVV-----SGDSSAHLVEEIQLFPDPE 467 + ++ V+ + DG ++ V++LGT +GS+ K + S + ++EE+Q+F P Sbjct: 434 QQLHQIVVDRVEAEDG-TYDVIFLGTDSGSVLKVIALQAGGSAEPEEVVLEELQVFKVPT 492 Query: 468 PVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVY-ESCVDCVLARDPHCAWDPESRTCCLL 526 P+ ++++ + ++VG GV ++ C Y +C +C LARDP+CAWD S T Sbjct: 493 PITEMEISVKRQMLYVGSRLGVAQLRLHQCETYGTACAECCLARDPYCAWDGASCTHYRP 552 Query: 527 SAPNLNSWKQDMERGNPEWACASGPMSRSLRPQSRPQIIKE-VLAVPNSILELPCPHLSA 585 S +QD+ GNP C + +S ++ + V ++ L C S Sbjct: 553 SLGKRRFRRQDIRHGNPALQC----LGQSQEEEAVGLVAATMVYGTEHNSTFLECLPKSP 608 Query: 586 LASYYW------SHGPAAVPEASSTVY--NGSLLLIVQDGVGGLYQCWATENGFSYPVI 636 A+ W GP V ++ G L + G Y C E+GFS V+ Sbjct: 609 QAAVRWLLQRPGDEGPDQVKTDERVLHTERGLLFRRLSRFDAGTYTCTTLEHGFSQTVV 667 >gi|147904700 semaphorin 5A [Homo sapiens] Length = 1074 Score = 253 bits (645), Expect = 6e-67 Identities = 171/498 (34%), Positives = 257/498 (51%), Gaps = 33/498 (6%) Query: 56 FHQKGLQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVPRLKNMIPWPASDRKKSECAF 115 F K DF L L VGAR + L ++D L + W + K C Sbjct: 50 FRAKNAVDFSQLTFDPGQKELVVGARNYLFRLQLEDLS---LIQAVEWECDEATKKACYS 106 Query: 116 KKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQ 175 K KS E +C N+IRVL+ L+TCGT AF+P CT L S L I + + G + Sbjct: 107 KGKSKE-ECQNYIRVLL-VGGDRLFTCGTNAFTPVCTNRSL--SNLTEIHDQ--ISGMAR 160 Query: 176 SPFDPAHKHTAVLV-DGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNF-LRWLHHDASF 233 P+ P H TA+L G LY+ T +F G +P + R+LG P L+T + +WL+ + +F Sbjct: 161 CPYSPQHNSTALLTAGGELYAATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLN-EPNF 219 Query: 234 VAAIPSTQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLC 293 V++ YFFF E A E D + + SR ARVCKND+GG LL+ WTTF+KA+L C Sbjct: 220 VSSYDIGNFTYFFFRENAVEHDCGKTVF-SRAARVCKNDIGGRFLLEDTWTTFMKARLNC 278 Query: 294 TQPGQLPF--NVIRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFK 351 ++PG++PF N ++ L P IY +FT+ V +SAVC F+L I + F Sbjct: 279 SRPGEVPFYYNELQSTFFL----PELDLIYGIFTT--NVNSIAASAVCVFNLSAIAQAFS 332 Query: 352 GKYKELNKETSRWTTYRGPETNPRPGSCSVG---PSSDKALTFMKDHFLMDE---QVVGT 405 G +K S W Y P + + G+ G +++ L + LM E V Sbjct: 333 GPFKYQENSRSAWLPYPNPNPHFQCGTVDQGLYVNLTERNLQDAQKFILMHEVVQPVTTV 392 Query: 406 PLLVKSGVEYTRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVV--SGDSSAHLVEEIQLF 463 P ++ ++ +AV+ QG + H++ YL T G++ K V + SS+ L+EEI+LF Sbjct: 393 PSFMEDNSRFSHVAVDVVQGREALVHII-YLATDYGTIKKVRVPLNQTSSSCLLEEIELF 451 Query: 464 PD--PEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESCVDCVLARDPHCAWDPESR 521 P+ EP+R+LQ+ +Q +FVG V ++P C Y + C+ A+DP+C WD + Sbjct: 452 PERRREPIRSLQILHSQSVLFVGLREHVVKIPLKRCQFYRTRSTCIGAQDPYCGWDVVMK 511 Query: 522 TCCLL-SAPNLNSWKQDM 538 C L + ++ W+Q + Sbjct: 512 KCTSLEESLSMTQWEQSI 529 >gi|6912650 semaphorin 3E [Homo sapiens] Length = 775 Score = 252 bits (643), Expect = 1e-66 Identities = 190/662 (28%), Positives = 300/662 (45%), Gaps = 63/662 (9%) Query: 25 LLPTTTAGGGGQGPMPRVRYYAGD--ERRALSFFHQK-GLQDFDTLLLSGDGNTLYVGAR 81 LL T G PR+R + S FH G D T+LL L+VG R Sbjct: 16 LLELWTGGHTADTTHPRLRLSHKELLNLNRTSIFHSPFGFLDLHTMLLDEYQERLFVGGR 75 Query: 82 EAILALDIQDPGVPRLKNMIPWPASDRKKSECAFKKKSNETQCFNFIRVLVSYNVTHLYT 141 + + +L ++ + I WP++ K EC K K + +C N++RVL YN THL T Sbjct: 76 DLVYSLSLER--ISDGYKEIHWPSTALKMEECIMKGK-DAGECANYVRVLHHYNRTHLLT 132 Query: 142 CGTFAFSPACTFIELQ---DSYLLPISEDKVMEGKGQSPFDPAHKHTAVLVDGMLYSGTM 198 CGT AF P C FI + + L + + G+G+ PFDP+ + L+ L++G Sbjct: 133 CGTGAFDPVCAFIRVGYHLEDPLFHLESPRSERGRGRCPFDPSSSFISTLIGSELFAGLY 192 Query: 199 NNFLGSEPILMRTLGSQPVLKTDNFLRWLHHDASFVAA--IPSTQ-----VVYFFFEETA 251 +++ + + R++G ++T++ L + FV + IP + VYFFF E A Sbjct: 193 SDYWSRDAAIFRSMGRLAHIRTEHDDERLLKEPKFVGSYMIPDNEDRDDNKVYFFFTEKA 252 Query: 252 SEFDFFERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCTQPG----QLPFNVIRHA 307 E + +RV R+C NDVGG+++L KW+TFLKA+L+C+ PG F+ + Sbjct: 253 LEAENNAHAIYTRVGRLCVNDVGGQRILVNKWSTFLKARLVCSVPGMNGIDTYFDELEDV 312 Query: 308 VLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTY 367 LLP P I+ +F + + R A+C + + I F G Y W+ Y Sbjct: 313 FLLPTRDHKNPVIFGLFNTTSNI--FRGHAICVYHMSSIRAAFNGPYAHKEGPEYHWSVY 370 Query: 368 RGPETNPRPGSCSVGPSS----------DKALTFMKDHFLMDEQVVGT---PLLVKSGVE 414 G PRPGSC+ + D A+ F + H LM + + P+LVK+ + Sbjct: 371 EGKVPYPRPGSCASKVNGGRYGTTKDYPDDAIRFARSHPLMYQAIKPAHKKPILVKTDGK 430 Query: 415 YT--RLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSAH-----LVEEIQLFPDPE 467 Y ++AV+ + DG + V+++GT G + K + + ++EE+Q+F DP Sbjct: 431 YNLKQIAVDRVEAEDG-QYDVLFIGTDNGIVLKVITIYNQEMESMEEVILEELQIFKDPV 489 Query: 468 PVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYES-CVDCVLARDPHCAWDPESRTCCLL 526 P+ +++++ + +++G + V +V +C +Y S C DC LARDP+CAWD S C Sbjct: 490 PIISMEISSKRQQLYIGSASAVAQVRFHHCDMYGSACADCCLARDPYCAWDGIS---CSR 546 Query: 527 SAPNLNSWK-----QDMERGNPEWACASGPMSRSLRPQSRPQIIKEVLAVPNSILELPCP 581 P K QD+ GN C ++ + + N+ L C Sbjct: 547 YYPTGTHAKRRFRRQDVRHGNAAQQCFGQQFVGDALDKTEEHL---AYGIENNSTLLECT 603 Query: 582 HLSALASYYW--SHGPAAVPEASST------VYNGSLLLIVQDGVGGLYQCWATENGFSY 633 S A W G E T + G L L + G Y C E+ F + Sbjct: 604 PRSLQAKVIWFVQKGRETRKEEVKTDDRVVKMDLGLLFLRLHKSDAGTYFCQTVEHSFVH 663 Query: 634 PV 635 V Sbjct: 664 TV 665 >gi|11991660 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A [Homo sapiens] Length = 1030 Score = 244 bits (623), Expect = 2e-64 Identities = 166/508 (32%), Positives = 262/508 (51%), Gaps = 49/508 (9%) Query: 75 TLYVGAREAILALDIQDPGVPRL--KNMIPWPASDRKKSECAFKKKSNETQCFNFIRVLV 132 TLY+ AR+ I +DI + + W + C K K + +C NFI+VL+ Sbjct: 67 TLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKD-ECHNFIKVLL 125 Query: 133 SYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDPAHKHTAVLVDGM 192 N L+ CGT AF+P+C ++ L P ++ G + P+D H + A+ DG Sbjct: 126 KKNDDALFVCGTNAFNPSCRNYKMDT--LEPFGDE--FSGMARCPYDAKHANVALFADGK 181 Query: 193 LYSGTMNNFLGSEPILMRTLGSQPVLKT-DNFLRWLHHDASFVAAIPSTQVVYFFFEETA 251 LYS T+ +FL + ++ R+LG P L+T + +WL + FV A+ +YFFF E A Sbjct: 182 LYSATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWL-KEPYFVQAVDYGDYIYFFFREIA 240 Query: 252 SEFDFFERLHTSRVARVCKNDVGG-EKLLQKKWTTFLKAQLLCTQPG--QLPFNVIRHAV 308 E++ ++ RVA+VCKND+GG +++L+K+WT+FLKA+L C+ PG FN+++ AV Sbjct: 241 VEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQ-AV 299 Query: 309 LLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYR 368 + A F++ + SAVCA+ +LDI VF G++KE S WT Sbjct: 300 TDVIRINGRDVVLATFSTPY--NSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVP 357 Query: 369 GPET-NPRPGSCSVGPSS-----------DKALTFMKDHFLMDE---QVVGTPLLVKSGV 413 PRPG C+ G SS D L F+K H LMDE + P +++ V Sbjct: 358 DERVPKPRPGCCA-GSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMV 416 Query: 414 EY--TRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSAHL-----VEEIQLF--- 463 Y T++AV+TA G +H V++LG+ G + K + +S L +EE+ ++ Sbjct: 417 RYRLTKIAVDTAAG-PYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMSVYNSE 475 Query: 464 ------PDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESC-VDCVLARDPHCAW 516 + + + +QL +++V FS V +VP C + C C+ +RDP+C W Sbjct: 476 KCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGW 535 Query: 517 DPESRTCCLLSAPNLNSWKQDMERGNPE 544 E C LS + +++QD+ERGN + Sbjct: 536 IKEGGACSHLSPNSRLTFEQDIERGNTD 563 >gi|19718780 semaphorin 6B precursor [Homo sapiens] Length = 888 Score = 241 bits (614), Expect = 2e-63 Identities = 168/555 (30%), Positives = 283/555 (50%), Gaps = 48/555 (8%) Query: 59 KGLQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVPRLK--NMIPWPASDRKKSECAFK 116 +G D + + TL++G R+ + ++++ P L+ + W ++ + C K Sbjct: 60 EGADDLNIQRVLRVNRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMK 119 Query: 117 KKSNETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQS 176 K E +C NF++VL+ + + L+ CG+ AF+P C + L P+ ++ + G + Sbjct: 120 GKQ-EGECRNFVKVLLLRDESTLFVCGSNAFNPVCANYSIDT--LQPVGDN--ISGMARC 174 Query: 177 PFDPAHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNFLRWLHHDASFVAA 236 P+DP H + A+ DGML++ T+ +FL + ++ R+LG +P L+T + FV A Sbjct: 175 PYDPKHANVALFSDGMLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHA 234 Query: 237 IPSTQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGE-KLLQKKWTTFLKAQLLCTQ 295 + VYFFF E A EF++ E++ SRVARVCKNDVGG ++L+K+WT+FLKA+L C+ Sbjct: 235 VEWGSHVYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSV 294 Query: 296 PG--QLPFNVIRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGK 353 PG FNV++ AV P + AVF++ SAVCAF L + VF+G+ Sbjct: 295 PGDSHFYFNVLQ-AVTGVVSLGGRPVVLAVFST--PSNSIPGSAVCAFDLTQVAAVFEGR 351 Query: 354 YKELNKETSRWTTYRGPET-NPRPGSCSV--------GPSSDKALTFMKDHFLMDEQVVG 404 ++E S WT + PRPG C+ D L F+K H LMDE V Sbjct: 352 FREQKSPESIWTPVPEDQVPRPRPGCCAAPGMQYNASSALPDDILNFVKTHPLMDEAVPS 411 Query: 405 ---TPLLVKSGVEY--TRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSAH---- 455 P ++++ + + TR+AV+ G G + V++LG+ G++ K +V ++S Sbjct: 412 LGHAPWILRTLMRHQLTRVAVDVGAGPWG-NQTVVFLGSEAGTVLKFLVRPNASTSGTSG 470 Query: 456 ---LVEEIQLF-PD----------PEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYE 501 +EE + + PD + + +L+L G + F V RVP A C Y Sbjct: 471 LSVFLEEFETYRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYS 530 Query: 502 SCV-DCVLARDPHCAWDPESRTCCLLSAPNLNSWKQDMERGNPEWACASGPMSRSLRPQS 560 C+ +C+ ++DP+C W P+ +C LS +++QD+ + + R+ + Sbjct: 531 GCMKNCIGSQDPYCGWAPDG-SCIFLSPGTRAAFEQDVSGASTSGLGDCTGLLRASLSED 589 Query: 561 RPQIIKEVLAVPNSI 575 R ++ L V +S+ Sbjct: 590 RAGLVSVNLLVTSSV 604 >gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens] Length = 1073 Score = 234 bits (596), Expect = 3e-61 Identities = 175/565 (30%), Positives = 281/565 (49%), Gaps = 59/565 (10%) Query: 63 DFDTLLLSGDGNTLYVGAREAILALDIQD-PGVPRLKNM-IPWPASDRKKSECAFKKKSN 120 DF +L D TLY+ R+ + +++ + P + N + W + + + CA K K Sbjct: 58 DFQLMLKIRD--TLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHK 115 Query: 121 ETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDP 180 + +C NFI+V V N ++ CGT AF+P C + L + + + G + PFD Sbjct: 116 D-ECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEY----DGEEISGLARCPFDA 170 Query: 181 AHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNF-LRWLHHDASFVAAIPS 239 + A+ DG LYS T+ +FL S+ ++ R++G L+T + +W+ + F+ AI Sbjct: 171 RQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIK-EPHFLHAIEY 229 Query: 240 TQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGG-EKLLQKKWTTFLKAQLLCTQPGQ 298 VYFFF E A E + + SRVAR+CKND+GG +++L+K WT+FLKA+L C+ PG Sbjct: 230 GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGD 289 Query: 299 LPFNV-IRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKEL 357 F + ++ P + VFT+ Q+ SAVCAFS+ DIE+VFKG++KE Sbjct: 290 SFFYFDVLQSITDIIQINGIPTVVGVFTT--QLNSIPGSAVCAFSMDDIEKVFKGRFKEQ 347 Query: 358 NKETSRWTTYRGPE---TNPRPGSCSVGPSS----------DKALTFMKDHFLMDEQV-- 402 S WT PE PRPG C+ + D+ L+F+K H LMD V Sbjct: 348 KTPDSVWTAV--PEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPP 405 Query: 403 -VGTPLLVKSGVEY--TRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGD----SSAH 455 P K+ V Y T ++V+ + G ++ V+++G+ G + K + + + Sbjct: 406 IADEPWFTKTRVRYRLTAISVDHSAG-PYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSV 464 Query: 456 LVEEIQLF---------PDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESC-VD 505 L+EEI+ + + + V +LQL A++V FS + R+P + C Y SC Sbjct: 465 LLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKS 524 Query: 506 CVLARDPHCAWDPESRTCCLLSAPNL--NSWKQDMERGNPEWACASGPMSRSLRPQSRPQ 563 C+ +RDP+C W S+ C P + ++QD E GN G L + P Sbjct: 525 CIASRDPYCGW--LSQGSCGRVTPGMLAEGYEQDTEFGN---TAHLGDCHEILPTSTTPD 579 Query: 564 IIKEVLAVPNSILELPCPHLSALAS 588 ++ P S +E+ ++ +AS Sbjct: 580 Y--KIFGGPTSDMEVSSSSVTTMAS 602 >gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens] Length = 597 Score = 233 bits (594), Expect = 5e-61 Identities = 167/519 (32%), Positives = 265/519 (51%), Gaps = 54/519 (10%) Query: 63 DFDTLLLSGDGNTLYVGAREAILALDIQD-PGVPRLKNM-IPWPASDRKKSECAFKKKSN 120 DF +L D TLY+ R+ + +++ + P + N + W + + + CA K K Sbjct: 58 DFQLMLKIRD--TLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHK 115 Query: 121 ETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDP 180 + +C NFI+V V N ++ CGT AF+P C + L + + + G + PFD Sbjct: 116 D-ECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEY----DGEEISGLARCPFDA 170 Query: 181 AHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNF-LRWLHHDASFVAAIPS 239 + A+ DG LYS T+ +FL S+ ++ R++G L+T + +W+ + F+ AI Sbjct: 171 RQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIK-EPHFLHAIEY 229 Query: 240 TQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGG-EKLLQKKWTTFLKAQLLCTQPGQ 298 VYFFF E A E + + SRVAR+CKND+GG +++L+K WT+FLKA+L C+ PG Sbjct: 230 GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGD 289 Query: 299 LPFNV-IRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKEL 357 F + ++ P + VFT+ Q+ SAVCAFS+ DIE+VFKG++KE Sbjct: 290 SFFYFDVLQSITDIIQINGIPTVVGVFTT--QLNSIPGSAVCAFSMDDIEKVFKGRFKEQ 347 Query: 358 NKETSRWTTYRGPE---TNPRPGSCSVGPSS----------DKALTFMKDHFLMDEQV-- 402 S WT PE PRPG C+ + D+ L+F+K H LMD V Sbjct: 348 KTPDSVWTAV--PEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPP 405 Query: 403 -VGTPLLVKSGVEY--TRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGD----SSAH 455 P K+ V Y T ++V+ + G ++ V+++G+ G + K + + + Sbjct: 406 IADEPWFTKTRVRYRLTAISVDHSAG-PYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSV 464 Query: 456 LVEEIQLF---------PDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESC-VD 505 L+EEI+ + + + V +LQL A++V FS + R+P + C Y SC Sbjct: 465 LLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKS 524 Query: 506 CVLARDPHCAWDPESRTCCLLSAPNL--NSWKQDMERGN 542 C+ +RDP+C W S+ C P + ++QD E GN Sbjct: 525 CIASRDPYCGW--LSQGSCGRVTPGMLAEGYEQDTEFGN 561 >gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens] Length = 1017 Score = 233 bits (594), Expect = 5e-61 Identities = 167/519 (32%), Positives = 265/519 (51%), Gaps = 54/519 (10%) Query: 63 DFDTLLLSGDGNTLYVGAREAILALDIQD-PGVPRLKNM-IPWPASDRKKSECAFKKKSN 120 DF +L D TLY+ R+ + +++ + P + N + W + + + CA K K Sbjct: 58 DFQLMLKIRD--TLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHK 115 Query: 121 ETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDP 180 + +C NFI+V V N ++ CGT AF+P C + L + + + G + PFD Sbjct: 116 D-ECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEY----DGEEISGLARCPFDA 170 Query: 181 AHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNF-LRWLHHDASFVAAIPS 239 + A+ DG LYS T+ +FL S+ ++ R++G L+T + +W+ + F+ AI Sbjct: 171 RQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIK-EPHFLHAIEY 229 Query: 240 TQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGG-EKLLQKKWTTFLKAQLLCTQPGQ 298 VYFFF E A E + + SRVAR+CKND+GG +++L+K WT+FLKA+L C+ PG Sbjct: 230 GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGD 289 Query: 299 LPFNV-IRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKEL 357 F + ++ P + VFT+ Q+ SAVCAFS+ DIE+VFKG++KE Sbjct: 290 SFFYFDVLQSITDIIQINGIPTVVGVFTT--QLNSIPGSAVCAFSMDDIEKVFKGRFKEQ 347 Query: 358 NKETSRWTTYRGPE---TNPRPGSCSVGPSS----------DKALTFMKDHFLMDEQV-- 402 S WT PE PRPG C+ + D+ L+F+K H LMD V Sbjct: 348 KTPDSVWTAV--PEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPP 405 Query: 403 -VGTPLLVKSGVEY--TRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGD----SSAH 455 P K+ V Y T ++V+ + G ++ V+++G+ G + K + + + Sbjct: 406 IADEPWFTKTRVRYRLTAISVDHSAG-PYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSV 464 Query: 456 LVEEIQLF---------PDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESC-VD 505 L+EEI+ + + + V +LQL A++V FS + R+P + C Y SC Sbjct: 465 LLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKS 524 Query: 506 CVLARDPHCAWDPESRTCCLLSAPNL--NSWKQDMERGN 542 C+ +RDP+C W S+ C P + ++QD E GN Sbjct: 525 CIASRDPYCGW--LSQGSCGRVTPGMLAEGYEQDTEFGN 561 >gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens] Length = 998 Score = 233 bits (594), Expect = 5e-61 Identities = 167/519 (32%), Positives = 265/519 (51%), Gaps = 54/519 (10%) Query: 63 DFDTLLLSGDGNTLYVGAREAILALDIQD-PGVPRLKNM-IPWPASDRKKSECAFKKKSN 120 DF +L D TLY+ R+ + +++ + P + N + W + + + CA K K Sbjct: 58 DFQLMLKIRD--TLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHK 115 Query: 121 ETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDP 180 + +C NFI+V V N ++ CGT AF+P C + L + + + G + PFD Sbjct: 116 D-ECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEY----DGEEISGLARCPFDA 170 Query: 181 AHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNF-LRWLHHDASFVAAIPS 239 + A+ DG LYS T+ +FL S+ ++ R++G L+T + +W+ + F+ AI Sbjct: 171 RQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIK-EPHFLHAIEY 229 Query: 240 TQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGG-EKLLQKKWTTFLKAQLLCTQPGQ 298 VYFFF E A E + + SRVAR+CKND+GG +++L+K WT+FLKA+L C+ PG Sbjct: 230 GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGD 289 Query: 299 LPFNV-IRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKEL 357 F + ++ P + VFT+ Q+ SAVCAFS+ DIE+VFKG++KE Sbjct: 290 SFFYFDVLQSITDIIQINGIPTVVGVFTT--QLNSIPGSAVCAFSMDDIEKVFKGRFKEQ 347 Query: 358 NKETSRWTTYRGPE---TNPRPGSCSVGPSS----------DKALTFMKDHFLMDEQV-- 402 S WT PE PRPG C+ + D+ L+F+K H LMD V Sbjct: 348 KTPDSVWTAV--PEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPP 405 Query: 403 -VGTPLLVKSGVEY--TRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGD----SSAH 455 P K+ V Y T ++V+ + G ++ V+++G+ G + K + + + Sbjct: 406 IADEPWFTKTRVRYRLTAISVDHSAG-PYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSV 464 Query: 456 LVEEIQLF---------PDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESC-VD 505 L+EEI+ + + + V +LQL A++V FS + R+P + C Y SC Sbjct: 465 LLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKS 524 Query: 506 CVLARDPHCAWDPESRTCCLLSAPNL--NSWKQDMERGN 542 C+ +RDP+C W S+ C P + ++QD E GN Sbjct: 525 CIASRDPYCGW--LSQGSCGRVTPGMLAEGYEQDTEFGN 561 >gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens] Length = 1011 Score = 229 bits (584), Expect = 7e-60 Identities = 159/491 (32%), Positives = 253/491 (51%), Gaps = 50/491 (10%) Query: 63 DFDTLLLSGDGNTLYVGAREAILALDIQD-PGVPRLKNM-IPWPASDRKKSECAFKKKSN 120 DF +L D TLY+ R+ + +++ + P + N + W + + + CA K K Sbjct: 58 DFQLMLKIRD--TLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHK 115 Query: 121 ETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDP 180 + +C NFI+V V N ++ CGT AF+P C + L + + + G + PFD Sbjct: 116 D-ECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEY----DGEEISGLARCPFDA 170 Query: 181 AHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNF-LRWLHHDASFVAAIPS 239 + A+ DG LYS T+ +FL S+ ++ R++G L+T + +W+ + F+ AI Sbjct: 171 RQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIK-EPHFLHAIEY 229 Query: 240 TQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGG-EKLLQKKWTTFLKAQLLCTQPGQ 298 VYFFF E A E + + SRVAR+CKND+GG +++L+K WT+FLKA+L C+ PG Sbjct: 230 GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGD 289 Query: 299 LPFNV-IRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKEL 357 F + ++ P + VFT+ Q+ SAVCAFS+ DIE+VFKG++KE Sbjct: 290 SFFYFDVLQSITDIIQINGIPTVVGVFTT--QLNSIPGSAVCAFSMDDIEKVFKGRFKEQ 347 Query: 358 NKETSRWTTYRGPE---TNPRPGSCSVGPSS----------DKALTFMKDHFLMDEQV-- 402 S WT PE PRPG C+ + D+ L+F+K H LMD V Sbjct: 348 KTPDSVWTAV--PEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPP 405 Query: 403 -VGTPLLVKSGVEY--TRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGD----SSAH 455 P K+ V Y T ++V+ + G ++ V+++G+ G + K + + + Sbjct: 406 IADEPWFTKTRVRYRLTAISVDHSAG-PYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSV 464 Query: 456 LVEEIQLF---------PDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESC-VD 505 L+EEI+ + + + V +LQL A++V FS + R+P + C Y SC Sbjct: 465 LLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKS 524 Query: 506 CVLARDPHCAW 516 C+ +RDP+C W Sbjct: 525 CIASRDPYCGW 535 >gi|16306552 semaphorin Y [Homo sapiens] Length = 930 Score = 218 bits (554), Expect = 2e-56 Identities = 179/554 (32%), Positives = 271/554 (48%), Gaps = 67/554 (12%) Query: 18 LFQLLQLLLPTTTAGGGGQGPMPRV----------RYYAGDERRALSFFHQKGLQDFDTL 67 L LL L LP T A Q P+P + ++ G E A++ Q F TL Sbjct: 11 LLLLLLLSLPHTQAAFP-QDPLPLLISDLQGTSPLSWFRGLEDDAVAAELGLDFQRFLTL 69 Query: 68 LLSGDGNTLYVGAREAILALDIQ--DPGVPRLKNM-IPWPASDRKKSECAFKKKSNETQC 124 TL V AR+ + + D+Q + G + N + W + D + CA + K + +C Sbjct: 70 -----NRTLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRSQDVEN--CAVRGKLTD-EC 121 Query: 125 FNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDPAHKH 184 +N+IRVLV ++ L CGT +FSP C + E + + G+ + PFD + Sbjct: 122 YNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQ----QEGEELSGQARCPFDATQSN 177 Query: 185 TAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNF-LRWLHHDASFVAAIPSTQVV 243 A+ +G LYS T +F S+ ++ R+LG QP L++ + +WL + FV A+ V Sbjct: 178 VAIFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLR-EPHFVQALEHGDHV 236 Query: 244 YFFFEETASEFDFFERLHTSRVARVCKNDVGGE-KLLQKKWTTFLKAQLLCTQPGQLPFN 302 YFFF E + E R+ SRVARVCK D+GG + L + WT+FLK +L C+ PG F Sbjct: 237 YFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFY 296 Query: 303 V-IRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKET 361 + A+ P + ++ VFT+ Q SAVCAF L +IER F+GK+KE Sbjct: 297 FDVLQALTGPVNLHGRSALFGVFTT--QTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLD 354 Query: 362 SRWTTYRGPET-NPRPGSCS-VGPSS---------DKALTFMKDHFLMDEQVVGTPLLVK 410 WT +PRPGSC+ VG ++ D LTF+K H L+D V P+ + Sbjct: 355 GAWTPVSEDRVPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAV--PPVTHQ 412 Query: 411 SGVEYTRLAVETAQGLDG----HSHL-VMYLGTTTGSLHKAVVSGDSSAH----LVEEIQ 461 + T A+ T +DG HS++ VM+LG+ G++ K + G S L+EEI Sbjct: 413 PLLTLTSRALLTQVAVDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSGGPEPILLEEID 472 Query: 462 LF-----------PDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESCV-DCVLA 509 + + L+L +FV FSG + +P + C+ + +C C+ + Sbjct: 473 AYSPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLAS 532 Query: 510 RDPHCAWDPESRTC 523 +DP+C W SR C Sbjct: 533 QDPYCGWH-SSRGC 545 >gi|24234732 semaphorin 6D isoform 6 precursor [Homo sapiens] Length = 476 Score = 197 bits (500), Expect = 4e-50 Identities = 139/428 (32%), Positives = 222/428 (51%), Gaps = 40/428 (9%) Query: 63 DFDTLLLSGDGNTLYVGAREAILALDIQD-PGVPRLKNM-IPWPASDRKKSECAFKKKSN 120 DF +L D TLY+ R+ + +++ + P + N + W + + + CA K K Sbjct: 58 DFQLMLKIRD--TLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHK 115 Query: 121 ETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDP 180 + +C NFI+V V N ++ CGT AF+P C + L + + + G + PFD Sbjct: 116 D-ECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEY----DGEEISGLARCPFDA 170 Query: 181 AHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNF-LRWLHHDASFVAAIPS 239 + A+ DG LYS T+ +FL S+ ++ R++G L+T + +W+ + F+ AI Sbjct: 171 RQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIK-EPHFLHAIEY 229 Query: 240 TQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGG-EKLLQKKWTTFLKAQLLCTQPGQ 298 VYFFF E A E + + SRVAR+CKND+GG +++L+K WT+FLKA+L C+ PG Sbjct: 230 GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGD 289 Query: 299 LPFNV-IRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKEL 357 F + ++ P + VFT+ Q+ SAVCAFS+ DIE+VFKG++KE Sbjct: 290 SFFYFDVLQSITDIIQINGIPTVVGVFTT--QLNSIPGSAVCAFSMDDIEKVFKGRFKEQ 347 Query: 358 NKETSRWTTYRGPE---TNPRPGSCSVGPSS----------DKALTFMKDHFLMDEQV-- 402 S WT PE PRPG C+ + D+ L+F+K H LMD V Sbjct: 348 KTPDSVWTAV--PEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPP 405 Query: 403 -VGTPLLVKSGVEY--TRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGD----SSAH 455 P K+ V Y T ++V+ + G ++ V+++G+ G + K + + + Sbjct: 406 IADEPWFTKTRVRYRLTAISVDHSAG-PYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSV 464 Query: 456 LVEEIQLF 463 L+EEI+ + Sbjct: 465 LLEEIEAY 472 >gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens] Length = 652 Score = 166 bits (420), Expect = 7e-41 Identities = 173/607 (28%), Positives = 259/607 (42%), Gaps = 87/607 (14%) Query: 116 KKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQ 175 K S T C N+I L+ L CGT A P+C L + ++P+ E + G Sbjct: 104 KNASVRTDCENYI-TLLERRSEGLLACGTNARHPSCW--NLVNGTVVPLGEMR-----GY 155 Query: 176 SPFDPAHKHTAVLVDGMLYSGTMNN--FLGSEPILMRTLG------SQPVLKTDNFLRW- 226 +PF P +++ VL +G T+ + G P R G S V++ F++ Sbjct: 156 APFSP-DENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKAT 214 Query: 227 -LHHDASFVAAIPSTQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGEKLLQ-KKWT 284 +H D ++ +Y+FF E + + L+ SRVA++C+ D GGE L KW Sbjct: 215 IVHQDQAY------DDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWN 268 Query: 285 TFLKAQLLCTQPG-QLPFNVIRHAVLLPADSP--TAPHIYAVFTSQWQVGGTRSSAVCAF 341 TFLKA L+C+ FN ++ LLP S +Y VF++ W SAVC + Sbjct: 269 TFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY-----SAVCVY 323 Query: 342 SLLDIERVFKGKYKELNKETSRWTTYRGPETNPRPGSC--SVGPSSDKALTFMKDHFLMD 399 SL DI++VF+ TS Y NPRPG C P + H + Sbjct: 324 SLGDIDKVFR---------TSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVA 374 Query: 400 EQV-----VGTPLLVKSGVEYTRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGD--- 451 ++V + TPL S Y ++AV Q G + V+YL T G++HK V G+ Sbjct: 375 QRVEPMGPLKTPLF-HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEH 433 Query: 452 SSAHLVEEIQLFPDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVY-ESCVDCVLAR 510 S A + EIQ F ++ + L + ++V V +VP C VY C C+++R Sbjct: 434 SFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSR 493 Query: 511 DPHCAWDPESRTCCLLSAPNLNSWKQDMERGNPEWACASGPMSRSLRPQSRPQIIKEVLA 570 DP+C WD + C+ + S Q + P C + +P P +++V Sbjct: 494 DPYCGWD---QGRCISIYSSERSVLQSINPAEPHKECPNP------KPDKAP--LQKVSL 542 Query: 571 VPNSILELPCPHLSALASYYWSHGPAAVPEASSTVYNGSLLLIVQDGVG---GLYQCWAT 627 PNS L CP S A+Y W H + + +L +++ G Y C A Sbjct: 543 APNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFIENLTAQQYGHYFCEAQ 602 Query: 628 ENGFSYPVISYWVDSQDQTLALDPELAGIPREHVKVPLTRVSGGAALAAQQSYWPHFVTV 687 E SY+ ++Q L PE GI EH+ G A A S W + Sbjct: 603 EG-------SYFREAQHWQLL--PE-DGIMAEHLL--------GHACALAASLWLGVLPT 644 Query: 688 TVLFALV 694 L LV Sbjct: 645 LTLGLLV 651 >gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens] Length = 666 Score = 164 bits (416), Expect = 2e-40 Identities = 201/722 (27%), Positives = 304/722 (42%), Gaps = 114/722 (15%) Query: 10 PWSLLGLFLFQLLQLLLPTTTAGGGGQGPM---PRV----RYYAGDERRALSFFHQKGLQ 62 P + LGL L L+LLL A QG + PR+ + + G +R + F G Sbjct: 21 PPARLGLPL--RLRLLLLLWAAAASAQGHLRSGPRIFAVWKGHVGQDR--VDF----GQT 72 Query: 63 DFDTLLLSGDGNT-LYVGAREAILALDIQDPGVPRLKNMIPWPAS-DRKKSECAFKKKSN 120 + T+L G++ ++VG R + D P KN + K C K+ Sbjct: 73 EPHTVLFHEPGSSSVWVGGRGKVYLFDF-----PEGKNASVRTVNIGSTKGSCLDKR--- 124 Query: 121 ETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDP 180 C N+I L+ L CGT A P+C L + ++P+ E + G +PF P Sbjct: 125 --DCENYI-TLLERRSEGLLACGTNARHPSCW--NLVNGTVVPLGEMR-----GYAPFSP 174 Query: 181 AHKHTAVLVDGMLYSGTMNN--FLGSEPILMRTLG------SQPVLKTDNFLRW--LHHD 230 +++ VL +G T+ + G P R G S V++ F++ +H D Sbjct: 175 -DENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQD 233 Query: 231 ASFVAAIPSTQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGEKLLQ-KKWTTFLKA 289 ++ +Y+FF E + + L+ SRVA++C+ D GGE L KW TFLKA Sbjct: 234 QAY------DDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKA 287 Query: 290 QLLCTQPG-QLPFNVIRHAVLLPADSP--TAPHIYAVFTSQWQVGGTRSSAVCAFSLLDI 346 L+C+ FN ++ LLP S +Y VF++ W SAVC +SL DI Sbjct: 288 MLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY-----SAVCVYSLGDI 342 Query: 347 ERVFKGKYKELNKETSRWTTYRGPETNPRPGSC--SVGPSSDKALTFMKDHFLMDEQV-- 402 ++VF+ TS Y NPRPG C P + H + ++V Sbjct: 343 DKVFR---------TSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEP 393 Query: 403 ---VGTPLLVKSGVEYTRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGD---SSAHL 456 + TPL S Y ++AV Q G + V+YL T G++HK V G+ S A Sbjct: 394 MGPLKTPLF-HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFN 452 Query: 457 VEEIQLFPDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVY-ESCVDCVLARDPHCA 515 + EIQ F ++ + L + ++V V +VP C VY C C+++RDP+C Sbjct: 453 IMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCG 512 Query: 516 WDPESRTCCLLSAPNLNSWKQDMERGNPEWACASGPMSRSLRPQSRPQIIKEVLAVPNSI 575 WD + C+ + S Q + P C + +P P +++V PNS Sbjct: 513 WD---QGRCISIYSSERSVLQSINPAEPHKECPNP------KPDKAP--LQKVSLAPNSR 561 Query: 576 LELPCPHLSALASYYWSHGPAAVPEASSTVYNGSLLLIVQDGVG---GLYQCWATENGFS 632 L CP S A+Y W H + + +L +++ G Y C A E Sbjct: 562 YYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFIENLTAQQYGHYFCEAQEG--- 618 Query: 633 YPVISYWVDSQDQTLALDPELAGIPREHVKVPLTRVSGGAALAAQQSYWPHFVTVTVLFA 692 SY+ ++Q L PE GI EH+ G A A S W + L Sbjct: 619 ----SYFREAQHWQLL--PE-DGIMAEHLL--------GHACALAASLWLGVLPTLTLGL 663 Query: 693 LV 694 LV Sbjct: 664 LV 665 >gi|225637524 semaphorin 7A isoform 3 [Homo sapiens] Length = 501 Score = 152 bits (385), Expect = 9e-37 Identities = 156/550 (28%), Positives = 235/550 (42%), Gaps = 79/550 (14%) Query: 173 KGQSPFDPAHKHTAVLVDGMLYSGTMNN--FLGSEPILMRTLG------SQPVLKTDNFL 224 +G +PF P +++ VL +G T+ + G P R G S V++ F+ Sbjct: 2 RGYAPFSP-DENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFI 60 Query: 225 RW--LHHDASFVAAIPSTQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGEKLLQ-K 281 + +H D ++ +Y+FF E + + L+ SRVA++C+ D GGE L Sbjct: 61 KATIVHQDQAY------DDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVS 114 Query: 282 KWTTFLKAQLLCTQPG-QLPFNVIRHAVLLPADSP--TAPHIYAVFTSQWQVGGTRSSAV 338 KW TFLKA L+C+ FN ++ LLP S +Y VF++ W SAV Sbjct: 115 KWNTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY-----SAV 169 Query: 339 CAFSLLDIERVFKGKYKELNKETSRWTTYRGPETNPRPGSC--SVGPSSDKALTFMKDHF 396 C +SL DI++VF+ TS Y NPRPG C P + H Sbjct: 170 CVYSLGDIDKVFR---------TSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHP 220 Query: 397 LMDEQV-----VGTPLLVKSGVEYTRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGD 451 + ++V + TPL S Y ++AV Q G + V+YL T G++HK V G+ Sbjct: 221 EVAQRVEPMGPLKTPLF-HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGE 279 Query: 452 ---SSAHLVEEIQLFPDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVY-ESCVDCV 507 S A + EIQ F ++ + L + ++V V +VP C VY C C+ Sbjct: 280 QEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCL 339 Query: 508 LARDPHCAWDPESRTCCLLSAPNLNSWKQDMERGNPEWACASGPMSRSLRPQSRPQIIKE 567 ++RDP+C WD + C+ + S Q + P C + +P P +++ Sbjct: 340 MSRDPYCGWD---QGRCISIYSSERSVLQSINPAEPHKECPNP------KPDKAP--LQK 388 Query: 568 VLAVPNSILELPCPHLSALASYYWSHGPAAVPEASSTVYNGSLLLIVQDGVG---GLYQC 624 V PNS L CP S A+Y W H + + +L +++ G Y C Sbjct: 389 VSLAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFIENLTAQQYGHYFC 448 Query: 625 WATENGFSYPVISYWVDSQDQTLALDPELAGIPREHVKVPLTRVSGGAALAAQQSYWPHF 684 A E SY+ ++Q L PE GI EH+ G A A S W Sbjct: 449 EAQEG-------SYFREAQHWQLL--PE-DGIMAEHLL--------GHACALAASLWLGV 490 Query: 685 VTVTVLFALV 694 + L LV Sbjct: 491 LPTLTLGLLV 500 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.135 0.421 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,800,920 Number of Sequences: 37866 Number of extensions: 1532550 Number of successful extensions: 3647 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 43 Number of HSP's successfully gapped in prelim test: 5 Number of HSP's that attempted gapping in prelim test: 3359 Number of HSP's gapped (non-prelim): 64 length of query: 761 length of database: 18,247,518 effective HSP length: 110 effective length of query: 651 effective length of database: 14,082,258 effective search space: 9167549958 effective search space used: 9167549958 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.