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Search of human proteins with 21361914
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|21361914 semaphorin B [Homo sapiens]
(761 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|21361914 semaphorin B [Homo sapiens] 1557 0.0
gi|39777610 semaphorin 4B precursor [Homo sapiens] 471 e-133
gi|39777608 semaphorin 4B precursor [Homo sapiens] 471 e-133
gi|157388902 semaphorin 4C [Homo sapiens] 401 e-111
gi|214010218 semaphorin 4D isoform 1 [Homo sapiens] 385 e-106
gi|214010220 semaphorin 4D isoform 2 [Homo sapiens] 376 e-104
gi|28872814 semaphorin 4G [Homo sapiens] 341 2e-93
gi|19923279 semaphorin W [Homo sapiens] 337 2e-92
gi|5174673 semaphorin 3A precursor [Homo sapiens] 301 1e-81
gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens] 298 1e-80
gi|54607089 semaphorin 3B isoform 2 precursor [Homo sapiens] 297 3e-80
gi|188497703 semaphorin 3F [Homo sapiens] 291 2e-78
gi|41406086 semaphorin 3D [Homo sapiens] 288 1e-77
gi|5454048 semaphorin 3C [Homo sapiens] 282 7e-76
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens] 267 3e-71
gi|9910362 semaphorin sem2 [Homo sapiens] 263 6e-70
gi|147904700 semaphorin 5A [Homo sapiens] 253 6e-67
gi|6912650 semaphorin 3E [Homo sapiens] 252 1e-66
gi|11991660 sema domain, transmembrane domain (TM), and cytoplas... 244 2e-64
gi|19718780 semaphorin 6B precursor [Homo sapiens] 241 2e-63
gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens] 234 3e-61
gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens] 233 5e-61
gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens] 233 5e-61
gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens] 233 5e-61
gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens] 229 7e-60
gi|16306552 semaphorin Y [Homo sapiens] 218 2e-56
gi|24234732 semaphorin 6D isoform 6 precursor [Homo sapiens] 197 4e-50
gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens] 166 7e-41
gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens] 164 2e-40
gi|225637524 semaphorin 7A isoform 3 [Homo sapiens] 152 9e-37
>gi|21361914 semaphorin B [Homo sapiens]
Length = 761
Score = 1557 bits (4031), Expect = 0.0
Identities = 761/761 (100%), Positives = 761/761 (100%)
Query: 1 MALPALGLDPWSLLGLFLFQLLQLLLPTTTAGGGGQGPMPRVRYYAGDERRALSFFHQKG 60
MALPALGLDPWSLLGLFLFQLLQLLLPTTTAGGGGQGPMPRVRYYAGDERRALSFFHQKG
Sbjct: 1 MALPALGLDPWSLLGLFLFQLLQLLLPTTTAGGGGQGPMPRVRYYAGDERRALSFFHQKG 60
Query: 61 LQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVPRLKNMIPWPASDRKKSECAFKKKSN 120
LQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVPRLKNMIPWPASDRKKSECAFKKKSN
Sbjct: 61 LQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVPRLKNMIPWPASDRKKSECAFKKKSN 120
Query: 121 ETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDP 180
ETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDP
Sbjct: 121 ETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDP 180
Query: 181 AHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNFLRWLHHDASFVAAIPST 240
AHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNFLRWLHHDASFVAAIPST
Sbjct: 181 AHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNFLRWLHHDASFVAAIPST 240
Query: 241 QVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCTQPGQLP 300
QVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCTQPGQLP
Sbjct: 241 QVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCTQPGQLP 300
Query: 301 FNVIRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKE 360
FNVIRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKE
Sbjct: 301 FNVIRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKE 360
Query: 361 TSRWTTYRGPETNPRPGSCSVGPSSDKALTFMKDHFLMDEQVVGTPLLVKSGVEYTRLAV 420
TSRWTTYRGPETNPRPGSCSVGPSSDKALTFMKDHFLMDEQVVGTPLLVKSGVEYTRLAV
Sbjct: 361 TSRWTTYRGPETNPRPGSCSVGPSSDKALTFMKDHFLMDEQVVGTPLLVKSGVEYTRLAV 420
Query: 421 ETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSAHLVEEIQLFPDPEPVRNLQLAPTQGA 480
ETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSAHLVEEIQLFPDPEPVRNLQLAPTQGA
Sbjct: 421 ETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSAHLVEEIQLFPDPEPVRNLQLAPTQGA 480
Query: 481 VFVGFSGGVWRVPRANCSVYESCVDCVLARDPHCAWDPESRTCCLLSAPNLNSWKQDMER 540
VFVGFSGGVWRVPRANCSVYESCVDCVLARDPHCAWDPESRTCCLLSAPNLNSWKQDMER
Sbjct: 481 VFVGFSGGVWRVPRANCSVYESCVDCVLARDPHCAWDPESRTCCLLSAPNLNSWKQDMER 540
Query: 541 GNPEWACASGPMSRSLRPQSRPQIIKEVLAVPNSILELPCPHLSALASYYWSHGPAAVPE 600
GNPEWACASGPMSRSLRPQSRPQIIKEVLAVPNSILELPCPHLSALASYYWSHGPAAVPE
Sbjct: 541 GNPEWACASGPMSRSLRPQSRPQIIKEVLAVPNSILELPCPHLSALASYYWSHGPAAVPE 600
Query: 601 ASSTVYNGSLLLIVQDGVGGLYQCWATENGFSYPVISYWVDSQDQTLALDPELAGIPREH 660
ASSTVYNGSLLLIVQDGVGGLYQCWATENGFSYPVISYWVDSQDQTLALDPELAGIPREH
Sbjct: 601 ASSTVYNGSLLLIVQDGVGGLYQCWATENGFSYPVISYWVDSQDQTLALDPELAGIPREH 660
Query: 661 VKVPLTRVSGGAALAAQQSYWPHFVTVTVLFALVLSGALIILVASPLRALRARGKVQGCE 720
VKVPLTRVSGGAALAAQQSYWPHFVTVTVLFALVLSGALIILVASPLRALRARGKVQGCE
Sbjct: 661 VKVPLTRVSGGAALAAQQSYWPHFVTVTVLFALVLSGALIILVASPLRALRARGKVQGCE 720
Query: 721 TLRPGEKAPLSREQHLQSPKECRTSASDVDADNNCLGTEVA 761
TLRPGEKAPLSREQHLQSPKECRTSASDVDADNNCLGTEVA
Sbjct: 721 TLRPGEKAPLSREQHLQSPKECRTSASDVDADNNCLGTEVA 761
>gi|39777610 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 471 bits (1213), Expect = e-133
Identities = 297/760 (39%), Positives = 422/760 (55%), Gaps = 59/760 (7%)
Query: 5 ALGLDPWSLLGLFLFQLLQLLLPTTTAGGGGQGPMPRVRYYAGDERRALSFFHQKGLQDF 64
AL P LL L L LLQ PT PR+ G E R F + + ++
Sbjct: 18 ALPPRPPLLLLLLLLLLLQPPPPTWALS-------PRISLPLGSEERPFLRFEAEHISNY 70
Query: 65 DTLLLSGDGNTLYVGAREAILALDIQDPGVPRLKNM-IPWPASDRKKSECAFKKKSNETQ 123
LLLS DG TLYVGAREA+ AL +P + + W A KK +C+FK K +
Sbjct: 71 TALLLSRDGRTLYVGAREALFALSSNLSFLPGGEYQELLWGADAEKKQQCSFKGKDPQRD 130
Query: 124 CFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVM--EGKGQSPFDPA 181
C N+I++L+ + +HL+TCGT AFSP CT+I +++ L + V+ +GKG+ PFDP
Sbjct: 131 CQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLEDGKGRCPFDPN 190
Query: 182 HKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNFLRWLHHDASFVAA--IPS 239
K TA++VDG LY+GT+++F G++P + R+ +P KT++ L WL D +FVA+ IP
Sbjct: 191 FKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPT-KTESSLNWLQ-DPAFVASAYIPE 248
Query: 240 T--------QVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQL 291
+ +YFFF ET EF+FFE SR+AR+CK D GGE++LQ++WT+FLKAQL
Sbjct: 249 SLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQQRWTSFLKAQL 308
Query: 292 LCTQPGQ-LPFNVIRHAVLLPADSPTAPH-----IYAVFTSQWQVGGTRSSAVCAFSLLD 345
LC++P PFNV++ L SP+ Y VFTSQW G T SAVC F++ D
Sbjct: 309 LCSRPDDGFPFNVLQDVFTL---SPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCVFTMKD 365
Query: 346 IERVFKGKYKELNKETSRWTTYRGPETNPRPGSCSVGPS-----------SDKALTFMKD 394
++RVF G YKE+N+ET +W T P PRPG+C + D+ L F+KD
Sbjct: 366 VQRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRVLNFLKD 425
Query: 395 HFLMDEQVVGTPLLVKSGVEYTRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSA 454
HFLMD QV LL++ Y R+AV GL H++ V++LGT G LHKAV G
Sbjct: 426 HFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLH-HTYDVLFLGTGDGRLHKAVSVG-PRV 483
Query: 455 HLVEEIQLFPDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESCVDCVLARDPHC 514
H++EE+Q+F +PV+NL L +G ++ GV +VP ANCS+Y SC DC+LARDP+C
Sbjct: 484 HIIEELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARDPYC 543
Query: 515 AWDPESRTCCLLSAPNL--NSWKQDMERGNPEWAC-ASGPMSRSLRPQSRPQIIKEVLAV 571
AW S L P L W QD+E + + C AS +S S P + ++V
Sbjct: 544 AWSGSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSASSVVSPSFVPTGE-KPCEQVQFQ 602
Query: 572 PNSILELPCPHLSALASYYWSHGPAAVPEASS--TVYNGSLLLIVQDGVGGLYQCWATEN 629
PN++ L CP LS LA+ W A V ++S + G LLL+ +G +QCW+ E
Sbjct: 603 PNTVNTLACPLLSNLATRLWLRNGAPVNASASCHVLPTGDLLLVGTQQLGE-FQCWSLEE 661
Query: 630 GFSYPVISYWVDSQDQTLALDPELAG-IPREHVKVPLTRVS----GGAALAAQQSYWPHF 684
GF V SY + + +A + G +P V + +RVS G A+ A +SYW F
Sbjct: 662 GFQQLVASYCPEVVEDGVADQTDEGGSVP---VIISTSRVSAPAGGKASWGADRSYWKEF 718
Query: 685 VTVTVLFALVLSGALIILVASPLRALRARGKVQGCETLRP 724
+ + LF L + ++ L+ +++ K C ++ P
Sbjct: 719 LVMCTLFVLAVLLPVLFLLYRHRNSMKVFLKQGECASVHP 758
>gi|39777608 semaphorin 4B precursor [Homo sapiens]
Length = 837
Score = 471 bits (1213), Expect = e-133
Identities = 297/760 (39%), Positives = 422/760 (55%), Gaps = 59/760 (7%)
Query: 5 ALGLDPWSLLGLFLFQLLQLLLPTTTAGGGGQGPMPRVRYYAGDERRALSFFHQKGLQDF 64
AL P LL L L LLQ PT PR+ G E R F + + ++
Sbjct: 18 ALPPRPPLLLLLLLLLLLQPPPPTWALS-------PRISLPLGSEERPFLRFEAEHISNY 70
Query: 65 DTLLLSGDGNTLYVGAREAILALDIQDPGVPRLKNM-IPWPASDRKKSECAFKKKSNETQ 123
LLLS DG TLYVGAREA+ AL +P + + W A KK +C+FK K +
Sbjct: 71 TALLLSRDGRTLYVGAREALFALSSNLSFLPGGEYQELLWGADAEKKQQCSFKGKDPQRD 130
Query: 124 CFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVM--EGKGQSPFDPA 181
C N+I++L+ + +HL+TCGT AFSP CT+I +++ L + V+ +GKG+ PFDP
Sbjct: 131 CQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLEDGKGRCPFDPN 190
Query: 182 HKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNFLRWLHHDASFVAA--IPS 239
K TA++VDG LY+GT+++F G++P + R+ +P KT++ L WL D +FVA+ IP
Sbjct: 191 FKSTALVVDGELYTGTVSSFQGNDPAISRSQSLRPT-KTESSLNWLQ-DPAFVASAYIPE 248
Query: 240 T--------QVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQL 291
+ +YFFF ET EF+FFE SR+AR+CK D GGE++LQ++WT+FLKAQL
Sbjct: 249 SLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQQRWTSFLKAQL 308
Query: 292 LCTQPGQ-LPFNVIRHAVLLPADSPTAPH-----IYAVFTSQWQVGGTRSSAVCAFSLLD 345
LC++P PFNV++ L SP+ Y VFTSQW G T SAVC F++ D
Sbjct: 309 LCSRPDDGFPFNVLQDVFTL---SPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCVFTMKD 365
Query: 346 IERVFKGKYKELNKETSRWTTYRGPETNPRPGSCSVGPS-----------SDKALTFMKD 394
++RVF G YKE+N+ET +W T P PRPG+C + D+ L F+KD
Sbjct: 366 VQRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRVLNFLKD 425
Query: 395 HFLMDEQVVGTPLLVKSGVEYTRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSA 454
HFLMD QV LL++ Y R+AV GL H++ V++LGT G LHKAV G
Sbjct: 426 HFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLH-HTYDVLFLGTGDGRLHKAVSVG-PRV 483
Query: 455 HLVEEIQLFPDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESCVDCVLARDPHC 514
H++EE+Q+F +PV+NL L +G ++ GV +VP ANCS+Y SC DC+LARDP+C
Sbjct: 484 HIIEELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARDPYC 543
Query: 515 AWDPESRTCCLLSAPNL--NSWKQDMERGNPEWAC-ASGPMSRSLRPQSRPQIIKEVLAV 571
AW S L P L W QD+E + + C AS +S S P + ++V
Sbjct: 544 AWSGSSCKHVSLYQPQLATRPWIQDIEGASAKDLCSASSVVSPSFVPTGE-KPCEQVQFQ 602
Query: 572 PNSILELPCPHLSALASYYWSHGPAAVPEASS--TVYNGSLLLIVQDGVGGLYQCWATEN 629
PN++ L CP LS LA+ W A V ++S + G LLL+ +G +QCW+ E
Sbjct: 603 PNTVNTLACPLLSNLATRLWLRNGAPVNASASCHVLPTGDLLLVGTQQLGE-FQCWSLEE 661
Query: 630 GFSYPVISYWVDSQDQTLALDPELAG-IPREHVKVPLTRVS----GGAALAAQQSYWPHF 684
GF V SY + + +A + G +P V + +RVS G A+ A +SYW F
Sbjct: 662 GFQQLVASYCPEVVEDGVADQTDEGGSVP---VIISTSRVSAPAGGKASWGADRSYWKEF 718
Query: 685 VTVTVLFALVLSGALIILVASPLRALRARGKVQGCETLRP 724
+ + LF L + ++ L+ +++ K C ++ P
Sbjct: 719 LVMCTLFVLAVLLPVLFLLYRHRNSMKVFLKQGECASVHP 758
>gi|157388902 semaphorin 4C [Homo sapiens]
Length = 833
Score = 401 bits (1030), Expect = e-111
Identities = 246/633 (38%), Positives = 343/633 (54%), Gaps = 48/633 (7%)
Query: 39 MPRVRYYAGDERRALSFFHQKGLQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVPRLK 98
+PR +G+ + F Q G+QDF TL L+ LYVGAREA+ A ++ L+
Sbjct: 28 VPRKTVSSGELATVVRRFSQTGIQDFLTLTLTEPTGLLYVGAREALFAFSME---ALELQ 84
Query: 99 NMIPWPASDRKKSECAFKKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQD 158
I W A KK+EC K K+N+T+CFNFIR L YN +HLY CGT+AF P CT++ +
Sbjct: 85 GAISWEAPVEKKTECIQKGKNNQTECFNFIRFLQPYNASHLYVCGTYAFQPKCTYVNM-- 142
Query: 159 SYLLPISEDKVMEGKGQSPFDPAHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVL 218
+ + +GKG+ P+DPA H +LVDG LYS T+NNFLG+EPI++R +G +
Sbjct: 143 -LTFTLEHGEFEDGKGKCPYDPAKGHAGLLVDGELYSATLNNFLGTEPIILRNMGPHHSM 201
Query: 219 KTDNFLRWLHHDASFV--AAIPST--------QVVYFFFEETASEFDFFERLHTSRVARV 268
KT+ WL ++ FV A +P + VYFFF E A E D + +RVARV
Sbjct: 202 KTEYLAFWL-NEPHFVGSAYVPESVGSFTGDDDKVYFFFRERAVESDCYAEQVVARVARV 260
Query: 269 CKNDVGGEKLLQKKWTTFLKAQLLCTQPG-QLPFNVIRHAVLLPADSPTAPHIYAVFTSQ 327
CK D+GG + LQ+KWTTFLKA+L C+ P QL FN ++ L S + VF +Q
Sbjct: 261 CKGDMGGARTLQRKWTTFLKARLACSAPNWQLYFNQLQAMHTLQDTSWHNTTFFGVFQAQ 320
Query: 328 WQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYRGPETNPRPGSC-------- 379
W G SA+C + L +I+RVF+G YKE ++E +W Y P +PRPGSC
Sbjct: 321 W--GDMYLSAICEYQLEEIQRVFEGPYKEYHEEAQKWDRYTDPVPSPRPGSCINNWHRRH 378
Query: 380 ---SVGPSSDKALTFMKDHFLMDEQV---VGTPLLVKSGVEYTRLAVETAQGLDGHSHLV 433
S D L F+K H LM+EQV PLLVK G +T L + GLDG ++ V
Sbjct: 379 GYTSSLELPDNILNFVKKHPLMEEQVGPRWSRPLLVKKGTNFTHLVADRVTGLDGATYTV 438
Query: 434 MYLGTTTGSLHKAVVSGDSSAHLVEEIQLFPDPEPVRNLQLAPTQGAVFVGFSGGVWRVP 493
+++GT G L KAV G HL+EE+QLF D EP+R+L L+ ++ +F G + ++P
Sbjct: 439 LFIGTGDGWLLKAVSLG-PWVHLIEELQLF-DQEPMRSLVLSQSKKLLFAGSRSQLVQLP 496
Query: 494 RANCSVYESCVDCVLARDPHCAWDPESRTCCLLSAPNLNSWKQDMERGNPEWACASGPMS 553
A+C Y SC DCVLARDP+CAW + C + + + Q + + C + S
Sbjct: 497 VADCMKYRSCADCVLARDPYCAWSVNTSRCVAVGGHSGSLLIQHVMTSDTSGIC-NLRGS 555
Query: 554 RSLRPQSRPQIIKEVLAVPNSILELPCPHLSALASYYWSHGPAAVP--EASSTVYNGSLL 611
+ +RP K + V + L LPC S LA W+ G +P + S +Y+ L
Sbjct: 556 KKVRPTP-----KNITVVAGTDLVLPCHLSSNLAHARWTFGGRDLPAEQPGSFLYDARLQ 610
Query: 612 LIV----QDGVGGLYQCWATENGFSYPVISYWV 640
+V Q G Y C++ E G Y V
Sbjct: 611 ALVVMAAQPRHAGAYHCFSEEQGARLAAEGYLV 643
>gi|214010218 semaphorin 4D isoform 1 [Homo sapiens]
Length = 862
Score = 385 bits (988), Expect = e-106
Identities = 243/629 (38%), Positives = 340/629 (54%), Gaps = 64/629 (10%)
Query: 38 PMPRVRYYAGDERRALSF--FHQKGLQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVP 95
P+PR+ + E R + FH+ + ++ LLLS D +TLY+GAREA+ A++ + +
Sbjct: 26 PIPRITW----EHREVHLVQFHEPDIYNYSALLLSEDKDTLYIGAREAVFAVNALN--IS 79
Query: 96 RLKNMIPWPASDRKKSECAFKKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIE 155
++ + W S+ KK++CA K KS +T+C N+IRVL + T LY CGT AF PAC +
Sbjct: 80 EKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSATSLYVCGTNAFQPACDHLN 139
Query: 156 LQDSYLLPISEDKVMEGKGQSPFDPAHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQ 215
L L +ED GKG+ PFDPAH +T+V+VDG LYSGT NFLGSEPI+ R
Sbjct: 140 LTSFKFLGKNED----GKGRCPFDPAHSYTSVMVDGELYSGTSYNFLGSEPIISRNSSHS 195
Query: 216 PVLKTDNFLRWLHHDASFVAA-----IPST-----QVVYFFFEETASEFDFFERLHTSRV 265
P L+T+ + WL+ + SFV A P + VYFFF E + E++F R+ R+
Sbjct: 196 P-LRTEYAIPWLN-EPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSVEYEFVFRVLIPRI 253
Query: 266 ARVCKNDVGGEKLLQKKWTTFLKAQLLCTQPGQ-LPFNVIRHAVLLPADSPTAPHIYAVF 324
ARVCK D GG + LQKKWT+FLKA+L+C++P L FNV+R +L + P YA+F
Sbjct: 254 ARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLRSPGLKVPVFYALF 313
Query: 325 TSQWQVGGTRSSAVCAFSLLDIERVFK-GKYKE---LNKETSRWTTYRGPETNPRPGSCS 380
T Q+ SAVCA++L E VF GKY + + + ++W Y GP PRPG+C
Sbjct: 314 TP--QLNNVGLSAVCAYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNGPVPKPRPGACI 371
Query: 381 VGPS-----------SDKALTFMKDHFLMDEQVV---GTPLLVKSGVEYTRLAVETAQGL 426
+ DK L F+KDH LMD+ V P L+K V YT++ V+ Q L
Sbjct: 372 DSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNYTQIVVDRTQAL 431
Query: 427 DGHSHLVMYLGTTTGSLHKAVVSGDSSAHLVEEIQLFPDPEPVRNLQLAPTQG--AVFVG 484
DG + VM++ T G+LHKA +S + + H++EE QLF D EPV+ L L+ +G V+ G
Sbjct: 432 DGTVYDVMFVSTDRGALHKA-ISLEHAVHIIEETQLFQDFEPVQTLLLSSKKGNRFVYAG 490
Query: 485 FSGGVWRVPRANCSVYESCVDCVLARDPHCAWDPESRTCCLLSAPNLNSWKQDMERGNPE 544
+ GV + P A C + +C DCVLARDP+CAW P + TC L S E
Sbjct: 491 SNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSRGLIQEMSGDA 550
Query: 545 WACASGPMSRSLRPQSRPQIIKEVLAVPNSILELPCPHLSALASYYWSHGPAAVPEASST 604
C P ++ EL C S LA +W V +A S
Sbjct: 551 SVC----------PDKSKGSYRQHFFKHGGTAELKCSQKSNLARVFWKF-QNGVLKAESP 599
Query: 605 VY-----NGSLLLIVQDGVGGLYQCWATE 628
Y L+ + +G G+YQC + E
Sbjct: 600 KYGLMGRKNLLIFNLSEGDSGVYQCLSEE 628
>gi|214010220 semaphorin 4D isoform 2 [Homo sapiens]
Length = 738
Score = 376 bits (965), Expect = e-104
Identities = 221/522 (42%), Positives = 309/522 (59%), Gaps = 48/522 (9%)
Query: 38 PMPRVRYYAGDERRALSF--FHQKGLQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVP 95
P+PR+ + E R + FH+ + ++ LLLS D +TLY+GAREA+ A++ + +
Sbjct: 26 PIPRITW----EHREVHLVQFHEPDIYNYSALLLSEDKDTLYIGAREAVFAVNALN--IS 79
Query: 96 RLKNMIPWPASDRKKSECAFKKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIE 155
++ + W S+ KK++CA K KS +T+C N+IRVL + T LY CGT AF PAC +
Sbjct: 80 EKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSATSLYVCGTNAFQPACDHLN 139
Query: 156 LQDSYLLPISEDKVMEGKGQSPFDPAHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQ 215
L L +ED GKG+ PFDPAH +T+V+VDG LYSGT NFLGSEPI+ R
Sbjct: 140 LTSFKFLGKNED----GKGRCPFDPAHSYTSVMVDGELYSGTSYNFLGSEPIISRNSSHS 195
Query: 216 PVLKTDNFLRWLHHDASFVAA-----IPST-----QVVYFFFEETASEFDFFERLHTSRV 265
P L+T+ + WL+ + SFV A P + VYFFF E + E++F R+ R+
Sbjct: 196 P-LRTEYAIPWLN-EPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSVEYEFVFRVLIPRI 253
Query: 266 ARVCKNDVGGEKLLQKKWTTFLKAQLLCTQPGQ-LPFNVIRHAVLLPADSPTAPHIYAVF 324
ARVCK D GG + LQKKWT+FLKA+L+C++P L FNV+R +L + P YA+F
Sbjct: 254 ARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLRSPGLKVPVFYALF 313
Query: 325 TSQWQVGGTRSSAVCAFSLLDIERVFK-GKYKE---LNKETSRWTTYRGPETNPRPGSCS 380
T Q+ SAVCA++L E VF GKY + + + ++W Y GP PRPG+C
Sbjct: 314 TP--QLNNVGLSAVCAYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNGPVPKPRPGACI 371
Query: 381 VGPS-----------SDKALTFMKDHFLMDEQVV---GTPLLVKSGVEYTRLAVETAQGL 426
+ DK L F+KDH LMD+ V P L+K V YT++ V+ Q L
Sbjct: 372 DSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNYTQIVVDRTQAL 431
Query: 427 DGHSHLVMYLGTTTGSLHKAVVSGDSSAHLVEEIQLFPDPEPVRNLQLAPTQG--AVFVG 484
DG + VM++ T G+LHKA +S + + H++EE QLF D EPV+ L L+ +G V+ G
Sbjct: 432 DGTVYDVMFVSTDRGALHKA-ISLEHAVHIIEETQLFQDFEPVQTLLLSSKKGNRFVYAG 490
Query: 485 FSGGVWRVPRANCSVYESCVDCVLARDPHCAWDPESRTCCLL 526
+ GV + P A C + +C DCVLARDP+CAW P + TC L
Sbjct: 491 SNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVAL 532
>gi|28872814 semaphorin 4G [Homo sapiens]
Length = 843
Score = 341 bits (874), Expect = 2e-93
Identities = 247/692 (35%), Positives = 344/692 (49%), Gaps = 80/692 (11%)
Query: 57 HQKG-LQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVPRLKNMIPWPASDRKKSECAF 115
H KG Q++ TLLL L VGAR A+ +L D G K I W AS +S+C
Sbjct: 48 HFKGQAQNYSTLLLEEASARLLVGARGALFSLSANDIGDGAHKE-IHWEASPEMQSKCHQ 106
Query: 116 KKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQ 175
K K+N+T+CFN +R L N THLY CGT AF P C I+ + ++ LP S + EGK +
Sbjct: 107 KGKNNQTECFNHVRFLQRLNSTHLYACGTHAFQPLCAAIDAE-AFTLPTSFE---EGKEK 162
Query: 176 SPFDPAHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNFLRWLHHDASFV- 234
P+DPA T +++DG LY+ T F S P + R+ + + + WL+ DA FV
Sbjct: 163 CPYDPARGFTGLIIDGGLYTATRYEFR-SIPDIRRSRHPHSLRTEETPMHWLN-DAEFVF 220
Query: 235 ---------AAIPSTQVVYFFFEETASE-----FDFFERLH-TSRVARVCKNDVGGEKLL 279
+A+ VY+FF E A+E F H +RVARVCK D+GG+K+L
Sbjct: 221 SVLVRESKASAVGDDDKVYYFFTERATEEGSGSFTQSRSSHRVARVARVCKGDLGGKKIL 280
Query: 280 QKKWTTFLKAQLLCTQPGQLPFNVIRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVC 339
QKKWT+FLKA+L+C P + +R L A++ + H YA FT Q +SA+C
Sbjct: 281 QKKWTSFLKARLICHIP---LYETLRGVCSLDAETSSRTHFYAAFTLSTQWKTLEASAIC 337
Query: 340 AFSLLDIERVFKGKYKELNKETSRWTTYRGPETNPRPGSC------SVGPSSDK-----A 388
+ L +I+ VF G Y E + RW Y G PRPGSC S G +S +
Sbjct: 338 RYDLAEIQAVFAGPYMEYQDGSRRWGRYEGGVPEPRPGSCITDSLRSQGYNSSQDLPSLV 397
Query: 389 LTFMKDHFLMDEQVV---GTPLLVKSGVEYTRLAVETAQGLDGHSHLVMYLGTTTGSLHK 445
L F+K H LM VV G PLL+K + YT L G ++ +++LGT G +HK
Sbjct: 398 LDFVKLHPLMARPVVPTRGRPLLLKRNIRYTHLTGTPVTTPAGPTYDLLFLGTADGWIHK 457
Query: 446 AVVSGDSSAHLVEEIQLFPDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESCVD 505
AVV G S H++EE Q+F + + V NL ++ Q +++VG GV ++P ++CS Y SC D
Sbjct: 458 AVVLG-SGMHIIEETQVFRESQSVENLVISLLQHSLYVGAPSGVIQLPLSSCSRYRSCYD 516
Query: 506 CVLARDPHCAWDPESRTCCLL------SAPNLNSWKQDMERGNPEWACASGPMSRSLRPQ 559
C+LARDP+C WDP + C S + + QD+ERGN C S SR P
Sbjct: 517 CILARDPYCGWDPGTHACAAATTIANRSQGSRTALIQDIERGNR--GCES---SRDTGP- 570
Query: 560 SRPQIIKEVLAVPNSILELPCPHLSALASYYW----SHGPAAVPEASSTVYNGSLLLIVQ 615
P +K + + LPC S LA W S G + +G L+ Q
Sbjct: 571 --PPPLKTRSVLRGDDVLLPCDQPSNLARALWLLNGSMGLSDGQGGYRVGVDGLLVTDAQ 628
Query: 616 DGVGGLYQCWATENGFSYPVISYWVDSQDQTLALDPELAGIPREHVKVPLTRVSGGAALA 675
G Y C+A ENG + SY + + T A P+ P GA LA
Sbjct: 629 PEHSGNYGCYAEENGLRTLLASYSLTVRPATPAPAPKAPATP-------------GAQLA 675
Query: 676 AQQSYWPHFVTVTVLFALVLSGALIILVASPL 707
V + + A+ G L +++AS L
Sbjct: 676 PD-------VRLLYVLAIAALGGLCLILASSL 700
>gi|19923279 semaphorin W [Homo sapiens]
Length = 770
Score = 337 bits (865), Expect = 2e-92
Identities = 230/658 (34%), Positives = 328/658 (49%), Gaps = 58/658 (8%)
Query: 19 FQLLQLLLPTTTAGGGGQGPMPRVRYYAGDERRALSFFHQKGLQDFDTLLLSGDGNTLYV 78
F LL L + + G +PR + L+ F ++ LL+ +TLYV
Sbjct: 20 FPLLLLAVLSGPVSGRVPRSVPRTSLPISEADSCLTRFAVPHTYNYSVLLVDPASHTLYV 79
Query: 79 GAREAILALDIQDPGV-PRLKNMIPWPASDRKKSECAFKKKSNETQCFNFIRVLVSYNVT 137
GAR+ I AL + G PR I W + + C KK E +C NF+++L N +
Sbjct: 80 GARDTIFALSLPFSGERPR---RIDWMVPEAHRQNCR-KKGKKEDECHNFVQILAIANAS 135
Query: 138 HLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDPAHKHTAVLVDGMLYSGT 197
HL TCGTFAF P C I++ + +++ G+G+ PF+PA + AV+ G+LY+ T
Sbjct: 136 HLLTCGTFAFDPKCGVIDVSRFQQV----ERLESGRGKCPFEPAQRSAAVMAGGVLYAAT 191
Query: 198 MNNFLGSEPILMRTLG-SQPVLKTDNFLRWLHHDASFVAAIPSTQV----------VYFF 246
+ N+LG+EPI+ R +G ++ ++TD WL+ A FVAA+ + +YFF
Sbjct: 192 VKNYLGTEPIITRAVGRAEDWIRTDTLPSWLNAPA-FVAAVALSPAEWGDEDGDDEIYFF 250
Query: 247 FEETASEFDFFERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCTQP--GQLPFNVI 304
F ET+ FD +ER+ RVARVC D+GG K LQ++WTTFLKA LLC P G+ +
Sbjct: 251 FTETSRAFDSYERIKVPRVARVCAGDLGGRKTLQQRWTTFLKADLLCPGPEHGRASSVLQ 310
Query: 305 RHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRW 364
AVL P P Y +F+SQW+ G SAVCAF DI V G ++EL + +R
Sbjct: 311 DVAVLRPELGAGTPIFYGIFSSQWE--GATISAVCAFRPQDIRTVLNGPFRELKHDCNRG 368
Query: 365 TTYRGPET-NPRPGSC--------SVGPS---SDKALTFMKDHFLMDEQVV---GTPLLV 409
+ PRPG C G S D+ LTF++DH LMD V G PLLV
Sbjct: 369 LPVVDNDVPQPRPGECITNNMKLRHFGSSLSLPDRVLTFIRDHPLMDRPVFPADGHPLLV 428
Query: 410 KSGVEYTRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSAHLVEEIQLFPDPEPV 469
+ Y R+ L G + V+YLGT G LH+AV G + ++E++ LFP+P+PV
Sbjct: 429 TTDTAYLRVVAHRVTSLSGKEYDVLYLGTEDGHLHRAVRIG-AQLSVLEDLALFPEPQPV 487
Query: 470 RNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESCVDCVLARDPHCAWDPESRTCCLLSAP 529
N++L + VG V +V NC +SC +C+LA+DP CAW C+ A
Sbjct: 488 ENMKL--YHSWLLVGSRTEVTQVNTTNCGRLQSCSECILAQDPVCAWSFRLDE-CVAHAG 544
Query: 530 NLNSWKQDMERGNPEWACASGPMSRSLRPQSRPQIIKEVLAVPNSILELPCPHLSALASY 589
QD+E + C P R ++ EV + + LPC SA AS
Sbjct: 545 EHRGLVQDIESADVSSLCPKEPGER--------PVVFEVPVATAAHVVLPCSPSSAWASC 596
Query: 590 YWSHGPAAVPEASSTVYNGSLLLIVQDGVGGLYQCWATENGFSYPVISY---WVDSQD 644
W H P+ V + T L ++V G G Y C E G ++ V +Y W +D
Sbjct: 597 VW-HQPSGV--TALTPRRDGLEVVVTPGAMGAYACECQEGGAAHVVAAYSLVWGSQRD 651
>gi|5174673 semaphorin 3A precursor [Homo sapiens]
Length = 771
Score = 301 bits (771), Expect = 1e-81
Identities = 199/629 (31%), Positives = 310/629 (49%), Gaps = 58/629 (9%)
Query: 48 DERRALSFFHQKGLQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVPRLKNM--IPWPA 105
+ ++F + T LL + + LYVGA++ I + D+ + +K+ I WP
Sbjct: 41 ESNNVITFNGLANSSSYHTFLLDEERSRLYVGAKDHIFSFDLVN-----IKDFQKIVWPV 95
Query: 106 SDRKKSECAFKKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIEL---QDSYLL 162
S ++ EC + K +C NFI+VL +YN THLY CGT AF P CT+IE+ + +
Sbjct: 96 SYTRRDECKWAGKDILKECANFIKVLKAYNQTHLYACGTGAFHPICTYIEIGHHPEDNIF 155
Query: 163 PISEDKVMEGKGQSPFDPAHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDN 222
+ G+G+SP+DP ++L+DG LYSGT +F+G + + RTLG ++T+
Sbjct: 156 KLENSHFENGRGKSPYDPKLLTASLLIDGELYSGTAADFMGRDFAIFRTLGHHHPIRTEQ 215
Query: 223 F-LRWLHHDASFVAA-------IPSTQVVYFFFEETASEFDFFERLHTSRVARVCKNDVG 274
RWL +D F++A P VYFFF E A + + + +R+ ++CKND G
Sbjct: 216 HDSRWL-NDPKFISAHLISESDNPEDDKVYFFFRENAIDGEHSGKATHARIGQICKNDFG 274
Query: 275 GEKLLQKKWTTFLKAQLLCTQPG----QLPFNVIRHAVLLPADSPTAPHIYAVFTSQWQV 330
G + L KWTTFLKA+L+C+ PG F+ ++ L+ P P +Y VFT+ +
Sbjct: 275 GHRSLVNKWTTFLKARLICSVPGPNGIDTHFDELQDVFLMNFKDPKNPVVYGVFTTSSNI 334
Query: 331 GGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYRGPETNPRPGSC---------SV 381
+ SAVC +S+ D+ RVF G Y + +W Y+G PRPG+C S
Sbjct: 335 --FKGSAVCMYSMSDVRRVFLGPYAHRDGPNYQWVPYQGRVPYPRPGTCPSKTFGGFDST 392
Query: 382 GPSSDKALTFMKDHFLMDEQVV---GTPLLVKSGVEY--TRLAVETAQGLDGHSHLVMYL 436
D +TF + H M V P+++K+ V Y T++ V+ DG + VM++
Sbjct: 393 KDLPDDVITFARSHPAMYNPVFPMNNRPIVIKTDVNYQFTQIVVDRVDAEDG-QYDVMFI 451
Query: 437 GTTTGSLHKAV-----VSGDSSAHLVEEIQLFPDPEPVRNLQLAPTQGAVFVGFSGGVWR 491
GT G++ K V D L+EE+ +F +P + ++L+ Q +++G + GV +
Sbjct: 452 GTDVGTVLKVVSIPKETWYDLEEVLLEEMTVFREPTAISAMELSTKQQQLYIGSTAGVAQ 511
Query: 492 VPRANCSVY-ESCVDCVLARDPHCAWDPESRTCCLLSAPNLNSWKQDMERGNPEWACASG 550
+P C +Y ++C +C LARDP+CAWD + + +A + +QD+ G+P C+
Sbjct: 512 LPLHRCDIYGKACAECCLARDPYCAWDGSACSRYFPTAKR-RTRRQDIRNGDPLTHCSDL 570
Query: 551 PMSRSLRPQSRPQIIKEVLAVPNSILELPCPHLSALASYYWS--------HGPAAVPEAS 602
+II V NS L C S A YW V +
Sbjct: 571 HHDNHHGHSPEERII---YGVENSSTFLECSPKSQRALVYWQFQRRNEERKEEIRVDDHI 627
Query: 603 STVYNGSLLLIVQDGVGGLYQCWATENGF 631
G LL +Q G Y C A E+GF
Sbjct: 628 IRTDQGLLLRSLQQKDSGNYLCHAVEHGF 656
>gi|4759092 semaphorin 3B isoform 1 precursor [Homo sapiens]
Length = 749
Score = 298 bits (763), Expect = 1e-80
Identities = 201/651 (30%), Positives = 319/651 (49%), Gaps = 62/651 (9%)
Query: 32 GGGGQGPMP---RVRYYAGDERRALSFFHQKGLQDFDTLLLSGDGNTLYVGAREAILALD 88
G G P P R+ + L F + + LL+ + L+VGA + +L+
Sbjct: 20 GLGSAAPSPPRLRLSFQELQAWHGLQTFSLERTCCYQALLVDEERGRLFVGAENHVASLN 79
Query: 89 IQDPGVPRLKNMIPWPASDRKKSECAFKKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFS 148
+ + + + + WPA + EC + K T+C NF+++L +YN THL CGT AF
Sbjct: 80 LDN--ISKRAKKLAWPAPVEWREECNWAGKDIGTECMNFVKLLHAYNRTHLLACGTGAFH 137
Query: 149 PACTFIEL---QDSYLLPISEDKVMEGKGQSPFDPAHKHTAVLVDGMLYSGTMNNFLGSE 205
P C F+E+ + +L + ++ +GKG+SP+DP H+ +VLV LYSG + +G +
Sbjct: 138 PTCAFVEVGHRAEEPVLRLDPGRIEDGKGKSPYDPRHRAASVLVGEELYSGVAADLMGRD 197
Query: 206 PILMRTLGSQPVLKTD-NFLRWLHHDASFVAAI-------PSTQVVYFFFEETASEF-DF 256
+ R+LG +P L+T+ + RWL+ + FV P +YFFF ETA E
Sbjct: 198 FTIFRSLGQRPSLRTEPHDSRWLN-EPKFVKVFWIPESENPDDDKIYFFFRETAVEAAPA 256
Query: 257 FERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCTQP---GQLPFNVIRHAVLLPAD 313
RL SRV ++C+NDVGG++ L KWTTFLKA+L+C+ P G F+ ++ LL +
Sbjct: 257 LGRLSVSRVGQICRNDVGGQRSLVNKWTTFLKARLVCSVPGVEGDTHFDQLQDVFLLSSR 316
Query: 314 SPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYRGPETN 373
P +YAVF++ + + SAVC +S+ D+ R F G + +W +Y+G
Sbjct: 317 DHRTPLLYAVFSTSSSI--FQGSAVCVYSMNDVRRAFLGPFAHKEGPMHQWVSYQGRVPY 374
Query: 374 PRPGSC---------SVGPSSDKALTFMKDHFLMDEQVV---GTPLLVKSGVEY--TRLA 419
PRPG C S D + F ++H LM V+ G PL ++ G Y T++A
Sbjct: 375 PRPGMCPSKTFGTFSSTKDFPDDVIQFARNHPLMYNSVLPTGGRPLFLQVGANYTFTQIA 434
Query: 420 VETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSS-----AHLVEEIQLFPDPEPVRNLQL 474
+ DGH + V+++GT G++ K + S L+EE+ +F D V ++Q+
Sbjct: 435 ADRVAAADGH-YDVLFIGTDVGTVLKVISVPKGSRPSAEGLLLEELHVFEDSAAVTSMQI 493
Query: 475 APTQGAVFVGFSGGVWRVPRANCSVY-ESCVDCVLARDPHCAWDPESRTCCLLSAPNLNS 533
+ + ++V V ++ C+ + C +C LARDP+CAWD + T SA
Sbjct: 494 SSKRHQLYVASRSAVAQIALHRCAAHGRVCTECCLARDPYCAWDGVACTRFQPSAKR-RF 552
Query: 534 WKQDMERGNPEWACASGPMSRSLRPQSRPQIIK-EVLAVPNSILELPCPHLSALASYYW- 591
+QD+ G+P C+ SRP +++ +V V S L C S A W
Sbjct: 553 RRQDVRNGDPSTLCSG--------DSSRPALLEHKVFGVEGSSAFLECEPRSLQARVEWT 604
Query: 592 -------SHGPAAVPEASSTVYNGSLLLIVQDGVGGLYQCWATENGFSYPV 635
+H E + G LL ++ G+Y C A E GF+ P+
Sbjct: 605 FQRAGVTAHTQVLAEERTERTARGLLLRRLRRRDSGVYLCAAVEQGFTQPL 655
>gi|54607089 semaphorin 3B isoform 2 precursor [Homo sapiens]
Length = 748
Score = 297 bits (760), Expect = 3e-80
Identities = 202/651 (31%), Positives = 318/651 (48%), Gaps = 63/651 (9%)
Query: 32 GGGGQGPMP---RVRYYAGDERRALSFFHQKGLQDFDTLLLSGDGNTLYVGAREAILALD 88
G G P P R+ + L F + + LL+ + L+VGA + +L+
Sbjct: 20 GLGSAAPSPPRLRLSFQELQAWHGLQTFSLERTCCYQALLVDEERGRLFVGAENHVASLN 79
Query: 89 IQDPGVPRLKNMIPWPASDRKKSECAFKKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFS 148
+ + + + + WPA + EC + K T+C NF+++L +YN THL CGT AF
Sbjct: 80 LDN--ISKRAKKLAWPAPVEWREECNWAGKDIGTECMNFVKLLHAYNRTHLLACGTGAFH 137
Query: 149 PACTFIEL---QDSYLLPISEDKVMEGKGQSPFDPAHKHTAVLVDGMLYSGTMNNFLGSE 205
P C F+E+ + +L + ++ +GKG+SP+DP H+ +VLV LYSG + +G +
Sbjct: 138 PTCAFVEVGHRAEEPVLRLDPGRIEDGKGKSPYDPRHRAASVLVGEELYSGVAADLMGRD 197
Query: 206 PILMRTLGSQPVLKTD-NFLRWLHHDASFVAAI-------PSTQVVYFFFEETASEF-DF 256
+ R+LG +P L+T+ + RWL+ + FV P +YFFF ETA E
Sbjct: 198 FTIFRSLGQRPSLRTEPHDSRWLN-EPKFVKVFWIPESENPDDDKIYFFFRETAVEAAPA 256
Query: 257 FERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCTQP---GQLPFNVIRHAVLLPAD 313
RL SRV ++C+NDVGG++ L KWTTFLKA+L+C+ P G F+ ++ LL +
Sbjct: 257 LGRLSVSRVGQICRNDVGGQRSLVNKWTTFLKARLVCSVPGVEGDTHFDQLQDVFLLSSR 316
Query: 314 SPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYRGPETN 373
P +YAVF++ G SAVC +S+ D+ R F G + +W +Y+G
Sbjct: 317 DHRTPLLYAVFSTSSIFQG---SAVCVYSMNDVRRAFLGPFAHKEGPMHQWVSYQGRVPY 373
Query: 374 PRPGSC---------SVGPSSDKALTFMKDHFLMDEQVV---GTPLLVKSGVEY--TRLA 419
PRPG C S D + F ++H LM V+ G PL ++ G Y T++A
Sbjct: 374 PRPGMCPSKTFGTFSSTKDFPDDVIQFARNHPLMYNSVLPTGGRPLFLQVGANYTFTQIA 433
Query: 420 VETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSS-----AHLVEEIQLFPDPEPVRNLQL 474
+ DGH + V+++GT G++ K + S L+EE+ +F D V ++Q+
Sbjct: 434 ADRVAAADGH-YDVLFIGTDVGTVLKVISVPKGSRPSAEGLLLEELHVFEDSAAVTSMQI 492
Query: 475 APTQGAVFVGFSGGVWRVPRANCSVY-ESCVDCVLARDPHCAWDPESRTCCLLSAPNLNS 533
+ + ++V V ++ C+ + C +C LARDP+CAWD + T SA
Sbjct: 493 SSKRHQLYVASRSAVAQIALHRCAAHGRVCTECCLARDPYCAWDGVACTRFQPSAKR-RF 551
Query: 534 WKQDMERGNPEWACASGPMSRSLRPQSRPQIIK-EVLAVPNSILELPCPHLSALASYYW- 591
+QD+ G+P C+ SRP +++ +V V S L C S A W
Sbjct: 552 RRQDVRNGDPSTLCSG--------DSSRPALLEHKVFGVEGSSAFLECEPRSLQARVEWT 603
Query: 592 -------SHGPAAVPEASSTVYNGSLLLIVQDGVGGLYQCWATENGFSYPV 635
+H E + G LL ++ G+Y C A E GF+ P+
Sbjct: 604 FQRAGVTAHTQVLAEERTERTARGLLLRRLRRRDSGVYLCAAVEQGFTQPL 654
>gi|188497703 semaphorin 3F [Homo sapiens]
Length = 785
Score = 291 bits (744), Expect = 2e-78
Identities = 201/649 (30%), Positives = 311/649 (47%), Gaps = 91/649 (14%)
Query: 63 DFDTLLLSGDGNTLYVGAREAILALDIQDPGVPRLKNMIPWPASDRKKSECAFKKKSNET 122
D+ LL D + +YVG+++ +L+LD+ D + R +I W AS ++ EC K
Sbjct: 56 DYRILLKDEDHDRMYVGSKDYVLSLDLHD--INREPLIIHWAASPQRIEECVLSGKDVNG 113
Query: 123 QCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIEL-------------------------- 156
+C NF+R++ +N THLY CGT A++P CT++
Sbjct: 114 ECGNFVRLIQPWNRTHLYVCGTGAYNPMCTYVNRGRRAQATPWTQTQAVRGRGSRATDGA 173
Query: 157 --------QDSYLLPISEDKVMEGKGQSPFDPAHKHTAVLVDGMLYSGTMNNFLGSEPIL 208
+ Y+ + +++ GKG+ P+DP + L++ LY+G +F+G++ +
Sbjct: 174 LRPMPTAPRQDYIFYLEPERLESGKGKCPYDPKLDTASALINEELYAGVYIDFMGTDAAI 233
Query: 209 MRTLGSQPVLKTDNF-LRWLHHDASFVAA--IPST-----QVVYFFFEETASEFDFFERL 260
RTLG Q ++TD + RWL +D SF+ A IP + +YFFF E ++E +
Sbjct: 234 FRTLGKQTAMRTDQYNSRWL-NDPSFIHAELIPDSAERNDDKLYFFFRERSAEAPQSPAV 292
Query: 261 HTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCTQPG----QLPFNVIRHAVLLPADSPT 316
+ +R+ R+C ND GG L KW+TFLKA+L+C+ PG + F+ ++ +
Sbjct: 293 Y-ARIGRICLNDDGGHCCLVNKWSTFLKARLVCSVPGEDGIETHFDELQDVFVQQTQDVR 351
Query: 317 APHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYRGPETNPRP 376
P IYAVFTS V R SAVC +S+ DI VF G + +W + G PRP
Sbjct: 352 NPVIYAVFTSSGSV--FRGSAVCVYSMADIRMVFNGPFAHKEGPNYQWMPFSGKMPYPRP 409
Query: 377 GSCSVG---PS-------SDKALTFMKDHFLMDEQVV---GTPLLVKSGVEY--TRLAVE 421
G+C G PS D+ + FM+ H LM + V PL+V++G Y T +AV+
Sbjct: 410 GTCPGGTFTPSMKSTKDYPDEVINFMRSHPLMYQAVYPLQRRPLVVRTGAPYRLTTIAVD 469
Query: 422 TAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSAHL----VEEIQLFPDPEPVRNLQLAPT 477
DG + V++LGT G++ K +V L +EE+++F DP PV+ + ++
Sbjct: 470 QVDAADGR-YEVLFLGTDRGTVQKVIVLPKDDQELEELMLEEVEVFKDPAPVKTMTISSK 528
Query: 478 QGAVFVGFSGGVWRVPRANCSVY-ESCVDCVLARDPHCAWDPESRTCCLLSAPN-LNSWK 535
+ ++V + GV + C Y +C DC LARDP+CAWD + C +A + S +
Sbjct: 529 RQQLYVASAVGVTHLSLHRCQAYGAACADCCLARDPYCAWD--GQACSRYTASSKRRSRR 586
Query: 536 QDMERGNPEWACASGPMSRSLRPQSRPQIIKEV-LAVPNSILELPCPHLSALASYYW--- 591
QD+ GNP C R + ++ V V S L C S A+ W
Sbjct: 587 QDVRHGNPIRQC------RGFNSNANKNAVESVQYGVAGSAAFLECQPRSPQATVKWLFQ 640
Query: 592 -----SHGPAAVPEASSTVYNGSLLLIVQDGVGGLYQCWATENGFSYPV 635
+ G LL +Q GLY C ATEN F + V
Sbjct: 641 RDPGDRRREIRAEDRFLRTEQGLLLRALQLSDRGLYSCTATENNFKHVV 689
>gi|41406086 semaphorin 3D [Homo sapiens]
Length = 777
Score = 288 bits (737), Expect = 1e-77
Identities = 207/672 (30%), Positives = 320/672 (47%), Gaps = 67/672 (9%)
Query: 16 LFLFQLLQLLLPTTTAGGGGQGPMPRVRYYAGD---ERRALSFFHQKGLQDFDTLLLSGD 72
L + + L LP T G + +PR++ D + F DF TLLL +
Sbjct: 22 LMMLSMTMLFLPVT---GTLKQNIPRLKLTYKDLLLSNSCIPFLGSSEGLDFQTLLLDEE 78
Query: 73 GNTLYVGAREAILALDIQDPGVPRLKNMIPWPASDRKKSECAFKKKSNETQCFNFIRVLV 132
L +GA++ I L + D + + I WPA+ + C K T+C NFIRVL
Sbjct: 79 RGRLLLGAKDHIFLLSLVD--LNKNFKKIYWPAAKERVELCKLAGKDANTECANFIRVLQ 136
Query: 133 SYNVTHLYTCGTFAFSPACTFIEL---QDSYLLPISEDKVMEGKGQSPFDPAHKHTAVLV 189
YN TH+Y CGT AF P C +I+L ++ + + + G+ + PFDP +V+
Sbjct: 137 PYNKTHIYVCGTGAFHPICGYIDLGVYKEDIIFKLDTHNLESGRLKCPFDPQQPFASVMT 196
Query: 190 DGMLYSGTMNNFLGSEPILMRTLG---SQPVLKTDNFLRWLHHDASFVAAI-------PS 239
D LYSGT ++FLG + R+LG ++TD + + A F+ P
Sbjct: 197 DEYLYSGTASDFLGKDTAFTRSLGPTHDHHYIRTDISEHYWLNGAKFIGTFFIPDTYNPD 256
Query: 240 TQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCTQPG-- 297
+YFFF E++ E ++ SRV RVCKNDVGG++ L KWTTFLKA+L+C+ PG
Sbjct: 257 DDKIYFFFRESSQEGSTSDKTILSRVGRVCKNDVGGQRSLINKWTTFLKARLICSIPGSD 316
Query: 298 --QLPFNVIRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYK 355
F+ ++ LLP P +Y VFT+ + + SAVC +S+ DI VF G Y
Sbjct: 317 GADTYFDELQDIYLLPTRDERNPVVYGVFTTTSSI--FKGSAVCVYSMADIRAVFNGPYA 374
Query: 356 ELNKETSRWTTYRGPETNPRPGSC----------SVGPSSDKALTFMKDHFLMDEQ---V 402
RW Y G PRPG+C S D ++F+K H +M + V
Sbjct: 375 HKESADHRWVQYDGRIPYPRPGTCPSKTYDPLIKSTRDFPDDVISFIKRHSVMYKSVYPV 434
Query: 403 VGTPLLVKSGVEY--TRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSAHL---- 456
G P + V+Y T++ V+ DG + VM+LGT G++ K V ++
Sbjct: 435 AGGPTFKRINVDYRLTQIVVDHVIAEDG-QYDVMFLGTDIGTVLKVVSISKEKWNMEEVV 493
Query: 457 VEEIQLFPDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVY-ESCVDCVLARDPHCA 515
+EE+Q+F + N++L+ Q +++G G+ ++ C Y ++C DC LARDP+CA
Sbjct: 494 LEELQIFKHSSIILNMELSLKQQQLYIGSRDGLVQLSLHRCDTYGKACADCCLARDPYCA 553
Query: 516 WDPESRTCCLLSAP--NLNSWKQDMERGNPEWACASGPMSRSLRPQSRPQIIKEVLAVPN 573
WD + C AP + +QD++ G+P C + S+ ++ + K + +
Sbjct: 554 WDGNA---CSRYAPTSKRRARRQDVKYGDPITQC--WDIEDSISHETADE--KVIFGIEF 606
Query: 574 SILELPCPHLSALASYYW-------SHGPAAVPEAS--STVYNGSLLLIVQDGVGGLYQC 624
+ L C S A+ W H P+ T Y G L+ +Q G+Y C
Sbjct: 607 NSTFLECIPKSQQATIKWYIQRSGDEHREELKPDERIIKTEY-GLLIRSLQKKDSGMYYC 665
Query: 625 WATENGFSYPVI 636
A E+ F + ++
Sbjct: 666 KAQEHTFIHTIV 677
>gi|5454048 semaphorin 3C [Homo sapiens]
Length = 751
Score = 282 bits (722), Expect = 7e-76
Identities = 201/648 (31%), Positives = 316/648 (48%), Gaps = 60/648 (9%)
Query: 34 GGQGPMPRVRYYAGDERRALSFFHQKGLQ----DFDTLLLSGDGNTLYVGAREAILALDI 89
G P RV Y DE R L D+ LL+ D + +YVG+++ IL+L+I
Sbjct: 21 GSSQPQARV-YLTFDELRETKTSEYFSLSHHPLDYRILLMDEDQDRIYVGSKDHILSLNI 79
Query: 90 QDPGVPRLKNMIPWPASDRKKSECAFKKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFSP 149
+ L + WPAS K EC K C NF+RV+ ++N THLY CG+ AFSP
Sbjct: 80 NNISQEALS--VFWPASTIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSP 137
Query: 150 ACTFIE--LQDSYLLPISEDKVMEGKGQSPFDPAHKHTAVLVDGMLYSGTMNNFLGSEPI 207
CT++ + + + + K GKG+ F+P +V+++ L+SG +F+G++
Sbjct: 138 VCTYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAA 197
Query: 208 LMRTLGSQPVLKTDNF-LRWLHH----DASFV--AAIPSTQVVYFFFEETASEFDFFERL 260
+ R+L + ++TD +WL DA + P+ VYFFF+E ++ + +
Sbjct: 198 IFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKEKLTDNNRSTKQ 257
Query: 261 HTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCT----QPGQLPFNVIRHAVLLPADSPT 316
S +AR+C ND GG + L KWTTFLKA+L+C+ + F+ + LL D+P
Sbjct: 258 IHSMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLETDNPR 317
Query: 317 APHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYRGPETNPRP 376
+Y +FT+ V + SAVC + L DI+ VF G + + +Y+G PRP
Sbjct: 318 TTLVYGIFTTSSSV--FKGSAVCVYHLSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRP 375
Query: 377 GSCSVGPSS----------DKALTFMKDHFLMDEQVV---GTPLLVKSGVE--YTRLAVE 421
G+C G + D +TF+++H LM + PL+V+ G + YT++AV+
Sbjct: 376 GTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPIHKRPLIVRIGTDYKYTKIAVD 435
Query: 422 TAQGLDGHSHLVMYLGTTTGSLHKAVV----SGDSSAHLVEEIQLFPDPEPVRNLQLAPT 477
DG H V++LGT G++ K VV + S ++EE+++F + P+ ++++
Sbjct: 436 RVNAADGRYH-VLFLGTDRGTVQKVVVLPTNNSVSGELILEELEVFKNHAPITTMKISSK 494
Query: 478 QGAVFVGFSGGVWRVPRANCSVY-ESCVDCVLARDPHCAWDPESRTCCLLSAP--NLNSW 534
+ ++V + GV +V C +Y +C DC LARDP+CAWD S C P S
Sbjct: 495 KQQLYVSSNEGVSQVSLHRCHIYGTACADCCLARDPYCAWDGHS---CSRFYPTGKRRSR 551
Query: 535 KQDMERGNPEWACASGPMSRSLRPQSRPQIIKEVLAVPNSILELPCPHLSALASYYW--- 591
+QD+ GNP C + ++ +I++ V N+ L C S AS W
Sbjct: 552 RQDVRHGNPLTQCRGFNLKAY---RNAAEIVQ--YGVKNNTTFLECAPKSPQASIKWLLQ 606
Query: 592 ----SHGPAAVPEASSTVYNGSLLLIVQDGVGGLYQCWATENGFSYPV 635
+ E G L+ VQ GLY C ATEN F +
Sbjct: 607 KDKDRRKEVKLNERIIATSQGLLIRSVQGSDQGLYHCIATENSFKQTI 654
>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
Length = 1151
Score = 267 bits (682), Expect = 3e-71
Identities = 180/502 (35%), Positives = 273/502 (54%), Gaps = 34/502 (6%)
Query: 53 LSFFHQKGLQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVPRLKNMIPWPASDRKKSE 112
+S F G +DF L L GN L VGAR + L + + L W +S+ +
Sbjct: 115 VSNFTYPGARDFSQLALDPSGNQLIVGARNYLFRLSLANVS---LLQATEWASSEDTRRS 171
Query: 113 CAFKKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEG 172
C K K+ E +C N++RVL+ ++ CGT AFSP CT ++ + L + +K+ G
Sbjct: 172 CQSKGKTEE-ECQNYVRVLIVAG-RKVFMCGTNAFSPMCTSRQVGN---LSRTIEKI-NG 225
Query: 173 KGQSPFDPAHKHTAVLVD-GMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNF-LRWLHHD 230
+ P+DP H TAV+ G LY+ T+ +F G +P + R+LGS P L+T + +WL+ +
Sbjct: 226 VARCPYDPRHNSTAVISSQGELYAATVIDFSGRDPAIYRSLGSGPPLRTAQYNSKWLN-E 284
Query: 231 ASFVAAIPSTQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQ 290
+FVAA YFF E A E D ++ SRVARVCKNDVGG LL+ WTTF+KA+
Sbjct: 285 PNFVAAYDIGLFAYFFLRENAVEHDCGRTVY-SRVARVCKNDVGGRFLLEDTWTTFMKAR 343
Query: 291 LLCTQPGQLPF--NVIRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIER 348
L C++PG++PF N ++ A LP IY VFT+ V +SAVCAF+L I +
Sbjct: 344 LNCSRPGEVPFYYNELQSAFHLPEQD----LIYGVFTT--NVNSIAASAVCAFNLSAISQ 397
Query: 349 VFKGKYKELNKETSRWTTYRGPETNPRPGSC-SVGPS---SDKALTFMKDHFLMDE---Q 401
F G ++ + W P N + G+ GP+ ++++L + FLM E
Sbjct: 398 AFNGPFRYQENPRAAWLPIANPIPNFQCGTLPETGPNENLTERSLQDAQRLFLMSEAVQP 457
Query: 402 VVGTPLLVKSGVEYTRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSAH--LVEE 459
V P + + V ++ L V+ Q D H V+Y+GT +G++ KA+ + S H +EE
Sbjct: 458 VTPEPCVTQDSVRFSHLVVDLVQAKDTLYH-VLYIGTESGTILKALSTASRSLHGCYLEE 516
Query: 460 IQLFPD--PEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESCVDCVLARDPHCAWD 517
+ + P EP+R+L++ + A+FVG GV RVP C+ Y S C+ ARDP+C WD
Sbjct: 517 LHVLPPGRREPLRSLRILHSARALFVGLRDGVLRVPLERCAAYRSQGACLGARDPYCGWD 576
Query: 518 PESRTCCLL-SAPNLNSWKQDM 538
+ + C L + N++ W Q++
Sbjct: 577 GKQQRCSTLEDSSNMSLWTQNI 598
>gi|9910362 semaphorin sem2 [Homo sapiens]
Length = 782
Score = 263 bits (671), Expect = 6e-70
Identities = 199/659 (30%), Positives = 314/659 (47%), Gaps = 65/659 (9%)
Query: 33 GGGQGP-----MPRVRYYAGD---ERRALSFFHQKGLQDFDTLLLSGDGNTLYVGAREAI 84
GG GP +PR+R D R+ F +G + + L + L++G +A+
Sbjct: 19 GGSSGPSPGPSVPRLRLSYRDLLSANRSAIFLGPQGSLNLQAMYLDEYRDRLFLGGLDAL 78
Query: 85 LALDIQDPGVPRLKNMIPWPASDRKKSECAFKKKSNETQCFNFIRVLVSYNVTHLYTCGT 144
+L + D P + ++ WP ++ EC K + T+C NF+RVL +N THL CGT
Sbjct: 79 YSLRL-DQAWPDPREVL-WPPQPGQREECVRKGRDPLTECANFVRVLQPHNRTHLLACGT 136
Query: 145 FAFSPACTFIEL--QDSYLLPISEDKVMEGKGQSPFDPAHKHTAVLVDGMLYSGTMNNFL 202
AF P C I + + ++L + V G+G+ P +P+ + +DG LY+G +FL
Sbjct: 137 GAFQPTCALITVGHRGEHVLHLEPGSVESGRGRCPHEPSRPFASTFIDGELYTGLTADFL 196
Query: 203 GSEPILMRTLGSQPVLKTDNFLRWLHHDASFVAA--IPSTQ-----VVYFFFEETASEFD 255
G E ++ R+ G +P L++D+ LH D FV A IP VYFFF ET D
Sbjct: 197 GREAMIFRSGGPRPALRSDSDQSLLH-DPRFVMAARIPENSDQDNDKVYFFFSETVPSPD 255
Query: 256 F-FERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCTQPG----QLPFNVIRHAVLL 310
+ SRV RVC ND GG+++L KW+TFLKA+L+C+ PG + F+ + LL
Sbjct: 256 GGSNHVTVSRVGRVCVNDAGGQRVLVNKWSTFLKARLVCSVPGPGGAETHFDQLEDVFLL 315
Query: 311 PADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYRGP 370
+ + +YA+F++ V + AVC + + DI VF G + + +W Y G
Sbjct: 316 WPKAGKSLEVYALFSTVSAV--FQGFAVCVYHMADIWEVFNGPFAHRDGPQHQWGPYGGK 373
Query: 371 ETNPRPGSC-------------SVGPSSDKALTFMKDHFLMDEQV---VGTPLLVKSGV- 413
PRPG C S D+ L F + H LM V G P+LVK+ +
Sbjct: 374 VPFPRPGVCPSKMTAQPGRPFGSTKDYPDEVLQFARAHPLMFWPVRPRHGRPVLVKTHLA 433
Query: 414 -EYTRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVV-----SGDSSAHLVEEIQLFPDPE 467
+ ++ V+ + DG ++ V++LGT +GS+ K + S + ++EE+Q+F P
Sbjct: 434 QQLHQIVVDRVEAEDG-TYDVIFLGTDSGSVLKVIALQAGGSAEPEEVVLEELQVFKVPT 492
Query: 468 PVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVY-ESCVDCVLARDPHCAWDPESRTCCLL 526
P+ ++++ + ++VG GV ++ C Y +C +C LARDP+CAWD S T
Sbjct: 493 PITEMEISVKRQMLYVGSRLGVAQLRLHQCETYGTACAECCLARDPYCAWDGASCTHYRP 552
Query: 527 SAPNLNSWKQDMERGNPEWACASGPMSRSLRPQSRPQIIKE-VLAVPNSILELPCPHLSA 585
S +QD+ GNP C + +S ++ + V ++ L C S
Sbjct: 553 SLGKRRFRRQDIRHGNPALQC----LGQSQEEEAVGLVAATMVYGTEHNSTFLECLPKSP 608
Query: 586 LASYYW------SHGPAAVPEASSTVY--NGSLLLIVQDGVGGLYQCWATENGFSYPVI 636
A+ W GP V ++ G L + G Y C E+GFS V+
Sbjct: 609 QAAVRWLLQRPGDEGPDQVKTDERVLHTERGLLFRRLSRFDAGTYTCTTLEHGFSQTVV 667
>gi|147904700 semaphorin 5A [Homo sapiens]
Length = 1074
Score = 253 bits (645), Expect = 6e-67
Identities = 171/498 (34%), Positives = 257/498 (51%), Gaps = 33/498 (6%)
Query: 56 FHQKGLQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVPRLKNMIPWPASDRKKSECAF 115
F K DF L L VGAR + L ++D L + W + K C
Sbjct: 50 FRAKNAVDFSQLTFDPGQKELVVGARNYLFRLQLEDLS---LIQAVEWECDEATKKACYS 106
Query: 116 KKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQ 175
K KS E +C N+IRVL+ L+TCGT AF+P CT L S L I + + G +
Sbjct: 107 KGKSKE-ECQNYIRVLL-VGGDRLFTCGTNAFTPVCTNRSL--SNLTEIHDQ--ISGMAR 160
Query: 176 SPFDPAHKHTAVLV-DGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNF-LRWLHHDASF 233
P+ P H TA+L G LY+ T +F G +P + R+LG P L+T + +WL+ + +F
Sbjct: 161 CPYSPQHNSTALLTAGGELYAATAMDFPGRDPAIYRSLGILPPLRTAQYNSKWLN-EPNF 219
Query: 234 VAAIPSTQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLC 293
V++ YFFF E A E D + + SR ARVCKND+GG LL+ WTTF+KA+L C
Sbjct: 220 VSSYDIGNFTYFFFRENAVEHDCGKTVF-SRAARVCKNDIGGRFLLEDTWTTFMKARLNC 278
Query: 294 TQPGQLPF--NVIRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFK 351
++PG++PF N ++ L P IY +FT+ V +SAVC F+L I + F
Sbjct: 279 SRPGEVPFYYNELQSTFFL----PELDLIYGIFTT--NVNSIAASAVCVFNLSAIAQAFS 332
Query: 352 GKYKELNKETSRWTTYRGPETNPRPGSCSVG---PSSDKALTFMKDHFLMDE---QVVGT 405
G +K S W Y P + + G+ G +++ L + LM E V
Sbjct: 333 GPFKYQENSRSAWLPYPNPNPHFQCGTVDQGLYVNLTERNLQDAQKFILMHEVVQPVTTV 392
Query: 406 PLLVKSGVEYTRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVV--SGDSSAHLVEEIQLF 463
P ++ ++ +AV+ QG + H++ YL T G++ K V + SS+ L+EEI+LF
Sbjct: 393 PSFMEDNSRFSHVAVDVVQGREALVHII-YLATDYGTIKKVRVPLNQTSSSCLLEEIELF 451
Query: 464 PD--PEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESCVDCVLARDPHCAWDPESR 521
P+ EP+R+LQ+ +Q +FVG V ++P C Y + C+ A+DP+C WD +
Sbjct: 452 PERRREPIRSLQILHSQSVLFVGLREHVVKIPLKRCQFYRTRSTCIGAQDPYCGWDVVMK 511
Query: 522 TCCLL-SAPNLNSWKQDM 538
C L + ++ W+Q +
Sbjct: 512 KCTSLEESLSMTQWEQSI 529
>gi|6912650 semaphorin 3E [Homo sapiens]
Length = 775
Score = 252 bits (643), Expect = 1e-66
Identities = 190/662 (28%), Positives = 300/662 (45%), Gaps = 63/662 (9%)
Query: 25 LLPTTTAGGGGQGPMPRVRYYAGD--ERRALSFFHQK-GLQDFDTLLLSGDGNTLYVGAR 81
LL T G PR+R + S FH G D T+LL L+VG R
Sbjct: 16 LLELWTGGHTADTTHPRLRLSHKELLNLNRTSIFHSPFGFLDLHTMLLDEYQERLFVGGR 75
Query: 82 EAILALDIQDPGVPRLKNMIPWPASDRKKSECAFKKKSNETQCFNFIRVLVSYNVTHLYT 141
+ + +L ++ + I WP++ K EC K K + +C N++RVL YN THL T
Sbjct: 76 DLVYSLSLER--ISDGYKEIHWPSTALKMEECIMKGK-DAGECANYVRVLHHYNRTHLLT 132
Query: 142 CGTFAFSPACTFIELQ---DSYLLPISEDKVMEGKGQSPFDPAHKHTAVLVDGMLYSGTM 198
CGT AF P C FI + + L + + G+G+ PFDP+ + L+ L++G
Sbjct: 133 CGTGAFDPVCAFIRVGYHLEDPLFHLESPRSERGRGRCPFDPSSSFISTLIGSELFAGLY 192
Query: 199 NNFLGSEPILMRTLGSQPVLKTDNFLRWLHHDASFVAA--IPSTQ-----VVYFFFEETA 251
+++ + + R++G ++T++ L + FV + IP + VYFFF E A
Sbjct: 193 SDYWSRDAAIFRSMGRLAHIRTEHDDERLLKEPKFVGSYMIPDNEDRDDNKVYFFFTEKA 252
Query: 252 SEFDFFERLHTSRVARVCKNDVGGEKLLQKKWTTFLKAQLLCTQPG----QLPFNVIRHA 307
E + +RV R+C NDVGG+++L KW+TFLKA+L+C+ PG F+ +
Sbjct: 253 LEAENNAHAIYTRVGRLCVNDVGGQRILVNKWSTFLKARLVCSVPGMNGIDTYFDELEDV 312
Query: 308 VLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTY 367
LLP P I+ +F + + R A+C + + I F G Y W+ Y
Sbjct: 313 FLLPTRDHKNPVIFGLFNTTSNI--FRGHAICVYHMSSIRAAFNGPYAHKEGPEYHWSVY 370
Query: 368 RGPETNPRPGSCSVGPSS----------DKALTFMKDHFLMDEQVVGT---PLLVKSGVE 414
G PRPGSC+ + D A+ F + H LM + + P+LVK+ +
Sbjct: 371 EGKVPYPRPGSCASKVNGGRYGTTKDYPDDAIRFARSHPLMYQAIKPAHKKPILVKTDGK 430
Query: 415 YT--RLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSAH-----LVEEIQLFPDPE 467
Y ++AV+ + DG + V+++GT G + K + + ++EE+Q+F DP
Sbjct: 431 YNLKQIAVDRVEAEDG-QYDVLFIGTDNGIVLKVITIYNQEMESMEEVILEELQIFKDPV 489
Query: 468 PVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYES-CVDCVLARDPHCAWDPESRTCCLL 526
P+ +++++ + +++G + V +V +C +Y S C DC LARDP+CAWD S C
Sbjct: 490 PIISMEISSKRQQLYIGSASAVAQVRFHHCDMYGSACADCCLARDPYCAWDGIS---CSR 546
Query: 527 SAPNLNSWK-----QDMERGNPEWACASGPMSRSLRPQSRPQIIKEVLAVPNSILELPCP 581
P K QD+ GN C ++ + + N+ L C
Sbjct: 547 YYPTGTHAKRRFRRQDVRHGNAAQQCFGQQFVGDALDKTEEHL---AYGIENNSTLLECT 603
Query: 582 HLSALASYYW--SHGPAAVPEASST------VYNGSLLLIVQDGVGGLYQCWATENGFSY 633
S A W G E T + G L L + G Y C E+ F +
Sbjct: 604 PRSLQAKVIWFVQKGRETRKEEVKTDDRVVKMDLGLLFLRLHKSDAGTYFCQTVEHSFVH 663
Query: 634 PV 635
V
Sbjct: 664 TV 665
>gi|11991660 sema domain, transmembrane domain (TM), and cytoplasmic
domain, (semaphorin) 6A [Homo sapiens]
Length = 1030
Score = 244 bits (623), Expect = 2e-64
Identities = 166/508 (32%), Positives = 262/508 (51%), Gaps = 49/508 (9%)
Query: 75 TLYVGAREAILALDIQDPGVPRL--KNMIPWPASDRKKSECAFKKKSNETQCFNFIRVLV 132
TLY+ AR+ I +DI + + W + C K K + +C NFI+VL+
Sbjct: 67 TLYIAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKD-ECHNFIKVLL 125
Query: 133 SYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDPAHKHTAVLVDGM 192
N L+ CGT AF+P+C ++ L P ++ G + P+D H + A+ DG
Sbjct: 126 KKNDDALFVCGTNAFNPSCRNYKMDT--LEPFGDE--FSGMARCPYDAKHANVALFADGK 181
Query: 193 LYSGTMNNFLGSEPILMRTLGSQPVLKT-DNFLRWLHHDASFVAAIPSTQVVYFFFEETA 251
LYS T+ +FL + ++ R+LG P L+T + +WL + FV A+ +YFFF E A
Sbjct: 182 LYSATVTDFLAIDAVIYRSLGESPTLRTVKHDSKWL-KEPYFVQAVDYGDYIYFFFREIA 240
Query: 252 SEFDFFERLHTSRVARVCKNDVGG-EKLLQKKWTTFLKAQLLCTQPG--QLPFNVIRHAV 308
E++ ++ RVA+VCKND+GG +++L+K+WT+FLKA+L C+ PG FN+++ AV
Sbjct: 241 VEYNTMGKVVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQ-AV 299
Query: 309 LLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKETSRWTTYR 368
+ A F++ + SAVCA+ +LDI VF G++KE S WT
Sbjct: 300 TDVIRINGRDVVLATFSTPY--NSIPGSAVCAYDMLDIASVFTGRFKEQKSPDSTWTPVP 357
Query: 369 GPET-NPRPGSCSVGPSS-----------DKALTFMKDHFLMDE---QVVGTPLLVKSGV 413
PRPG C+ G SS D L F+K H LMDE + P +++ V
Sbjct: 358 DERVPKPRPGCCA-GSSSLERYATSNEFPDDTLNFIKTHPLMDEAVPSIFNRPWFLRTMV 416
Query: 414 EY--TRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSAHL-----VEEIQLF--- 463
Y T++AV+TA G +H V++LG+ G + K + +S L +EE+ ++
Sbjct: 417 RYRLTKIAVDTAAG-PYQNHTVVFLGSEKGIILKFLARIGNSGFLNDSLFLEEMSVYNSE 475
Query: 464 ------PDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESC-VDCVLARDPHCAW 516
+ + + +QL +++V FS V +VP C + C C+ +RDP+C W
Sbjct: 476 KCSYDGVEDKRIMGMQLDRASSSLYVAFSTCVIKVPLGRCERHGKCKKTCIASRDPYCGW 535
Query: 517 DPESRTCCLLSAPNLNSWKQDMERGNPE 544
E C LS + +++QD+ERGN +
Sbjct: 536 IKEGGACSHLSPNSRLTFEQDIERGNTD 563
>gi|19718780 semaphorin 6B precursor [Homo sapiens]
Length = 888
Score = 241 bits (614), Expect = 2e-63
Identities = 168/555 (30%), Positives = 283/555 (50%), Gaps = 48/555 (8%)
Query: 59 KGLQDFDTLLLSGDGNTLYVGAREAILALDIQDPGVPRLK--NMIPWPASDRKKSECAFK 116
+G D + + TL++G R+ + ++++ P L+ + W ++ + C K
Sbjct: 60 EGADDLNIQRVLRVNRTLFIGDRDNLYRVELEPPTSTELRYQRKLTWRSNPSDINVCRMK 119
Query: 117 KKSNETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQS 176
K E +C NF++VL+ + + L+ CG+ AF+P C + L P+ ++ + G +
Sbjct: 120 GKQ-EGECRNFVKVLLLRDESTLFVCGSNAFNPVCANYSIDT--LQPVGDN--ISGMARC 174
Query: 177 PFDPAHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNFLRWLHHDASFVAA 236
P+DP H + A+ DGML++ T+ +FL + ++ R+LG +P L+T + FV A
Sbjct: 175 PYDPKHANVALFSDGMLFTATVTDFLAIDAVIYRSLGDRPTLRTVKHDSKWFKEPYFVHA 234
Query: 237 IPSTQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGE-KLLQKKWTTFLKAQLLCTQ 295
+ VYFFF E A EF++ E++ SRVARVCKNDVGG ++L+K+WT+FLKA+L C+
Sbjct: 235 VEWGSHVYFFFREIAMEFNYLEKVVVSRVARVCKNDVGGSPRVLEKQWTSFLKARLNCSV 294
Query: 296 PG--QLPFNVIRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGK 353
PG FNV++ AV P + AVF++ SAVCAF L + VF+G+
Sbjct: 295 PGDSHFYFNVLQ-AVTGVVSLGGRPVVLAVFST--PSNSIPGSAVCAFDLTQVAAVFEGR 351
Query: 354 YKELNKETSRWTTYRGPET-NPRPGSCSV--------GPSSDKALTFMKDHFLMDEQVVG 404
++E S WT + PRPG C+ D L F+K H LMDE V
Sbjct: 352 FREQKSPESIWTPVPEDQVPRPRPGCCAAPGMQYNASSALPDDILNFVKTHPLMDEAVPS 411
Query: 405 ---TPLLVKSGVEY--TRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGDSSAH---- 455
P ++++ + + TR+AV+ G G + V++LG+ G++ K +V ++S
Sbjct: 412 LGHAPWILRTLMRHQLTRVAVDVGAGPWG-NQTVVFLGSEAGTVLKFLVRPNASTSGTSG 470
Query: 456 ---LVEEIQLF-PD----------PEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYE 501
+EE + + PD + + +L+L G + F V RVP A C Y
Sbjct: 471 LSVFLEEFETYRPDRCGRPGGGETGQRLLSLELDAASGGLLAAFPRCVVRVPVARCQQYS 530
Query: 502 SCV-DCVLARDPHCAWDPESRTCCLLSAPNLNSWKQDMERGNPEWACASGPMSRSLRPQS 560
C+ +C+ ++DP+C W P+ +C LS +++QD+ + + R+ +
Sbjct: 531 GCMKNCIGSQDPYCGWAPDG-SCIFLSPGTRAAFEQDVSGASTSGLGDCTGLLRASLSED 589
Query: 561 RPQIIKEVLAVPNSI 575
R ++ L V +S+
Sbjct: 590 RAGLVSVNLLVTSSV 604
>gi|24234741 semaphorin 6D isoform 4 precursor [Homo sapiens]
Length = 1073
Score = 234 bits (596), Expect = 3e-61
Identities = 175/565 (30%), Positives = 281/565 (49%), Gaps = 59/565 (10%)
Query: 63 DFDTLLLSGDGNTLYVGAREAILALDIQD-PGVPRLKNM-IPWPASDRKKSECAFKKKSN 120
DF +L D TLY+ R+ + +++ + P + N + W + + + CA K K
Sbjct: 58 DFQLMLKIRD--TLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHK 115
Query: 121 ETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDP 180
+ +C NFI+V V N ++ CGT AF+P C + L + + + G + PFD
Sbjct: 116 D-ECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEY----DGEEISGLARCPFDA 170
Query: 181 AHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNF-LRWLHHDASFVAAIPS 239
+ A+ DG LYS T+ +FL S+ ++ R++G L+T + +W+ + F+ AI
Sbjct: 171 RQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIK-EPHFLHAIEY 229
Query: 240 TQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGG-EKLLQKKWTTFLKAQLLCTQPGQ 298
VYFFF E A E + + SRVAR+CKND+GG +++L+K WT+FLKA+L C+ PG
Sbjct: 230 GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGD 289
Query: 299 LPFNV-IRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKEL 357
F + ++ P + VFT+ Q+ SAVCAFS+ DIE+VFKG++KE
Sbjct: 290 SFFYFDVLQSITDIIQINGIPTVVGVFTT--QLNSIPGSAVCAFSMDDIEKVFKGRFKEQ 347
Query: 358 NKETSRWTTYRGPE---TNPRPGSCSVGPSS----------DKALTFMKDHFLMDEQV-- 402
S WT PE PRPG C+ + D+ L+F+K H LMD V
Sbjct: 348 KTPDSVWTAV--PEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPP 405
Query: 403 -VGTPLLVKSGVEY--TRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGD----SSAH 455
P K+ V Y T ++V+ + G ++ V+++G+ G + K + + +
Sbjct: 406 IADEPWFTKTRVRYRLTAISVDHSAG-PYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSV 464
Query: 456 LVEEIQLF---------PDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESC-VD 505
L+EEI+ + + + V +LQL A++V FS + R+P + C Y SC
Sbjct: 465 LLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKS 524
Query: 506 CVLARDPHCAWDPESRTCCLLSAPNL--NSWKQDMERGNPEWACASGPMSRSLRPQSRPQ 563
C+ +RDP+C W S+ C P + ++QD E GN G L + P
Sbjct: 525 CIASRDPYCGW--LSQGSCGRVTPGMLAEGYEQDTEFGN---TAHLGDCHEILPTSTTPD 579
Query: 564 IIKEVLAVPNSILELPCPHLSALAS 588
++ P S +E+ ++ +AS
Sbjct: 580 Y--KIFGGPTSDMEVSSSSVTTMAS 602
>gi|24234744 semaphorin 6D isoform 5 precursor [Homo sapiens]
Length = 597
Score = 233 bits (594), Expect = 5e-61
Identities = 167/519 (32%), Positives = 265/519 (51%), Gaps = 54/519 (10%)
Query: 63 DFDTLLLSGDGNTLYVGAREAILALDIQD-PGVPRLKNM-IPWPASDRKKSECAFKKKSN 120
DF +L D TLY+ R+ + +++ + P + N + W + + + CA K K
Sbjct: 58 DFQLMLKIRD--TLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHK 115
Query: 121 ETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDP 180
+ +C NFI+V V N ++ CGT AF+P C + L + + + G + PFD
Sbjct: 116 D-ECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEY----DGEEISGLARCPFDA 170
Query: 181 AHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNF-LRWLHHDASFVAAIPS 239
+ A+ DG LYS T+ +FL S+ ++ R++G L+T + +W+ + F+ AI
Sbjct: 171 RQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIK-EPHFLHAIEY 229
Query: 240 TQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGG-EKLLQKKWTTFLKAQLLCTQPGQ 298
VYFFF E A E + + SRVAR+CKND+GG +++L+K WT+FLKA+L C+ PG
Sbjct: 230 GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGD 289
Query: 299 LPFNV-IRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKEL 357
F + ++ P + VFT+ Q+ SAVCAFS+ DIE+VFKG++KE
Sbjct: 290 SFFYFDVLQSITDIIQINGIPTVVGVFTT--QLNSIPGSAVCAFSMDDIEKVFKGRFKEQ 347
Query: 358 NKETSRWTTYRGPE---TNPRPGSCSVGPSS----------DKALTFMKDHFLMDEQV-- 402
S WT PE PRPG C+ + D+ L+F+K H LMD V
Sbjct: 348 KTPDSVWTAV--PEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPP 405
Query: 403 -VGTPLLVKSGVEY--TRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGD----SSAH 455
P K+ V Y T ++V+ + G ++ V+++G+ G + K + + +
Sbjct: 406 IADEPWFTKTRVRYRLTAISVDHSAG-PYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSV 464
Query: 456 LVEEIQLF---------PDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESC-VD 505
L+EEI+ + + + V +LQL A++V FS + R+P + C Y SC
Sbjct: 465 LLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKS 524
Query: 506 CVLARDPHCAWDPESRTCCLLSAPNL--NSWKQDMERGN 542
C+ +RDP+C W S+ C P + ++QD E GN
Sbjct: 525 CIASRDPYCGW--LSQGSCGRVTPGMLAEGYEQDTEFGN 561
>gi|24234738 semaphorin 6D isoform 3 precursor [Homo sapiens]
Length = 1017
Score = 233 bits (594), Expect = 5e-61
Identities = 167/519 (32%), Positives = 265/519 (51%), Gaps = 54/519 (10%)
Query: 63 DFDTLLLSGDGNTLYVGAREAILALDIQD-PGVPRLKNM-IPWPASDRKKSECAFKKKSN 120
DF +L D TLY+ R+ + +++ + P + N + W + + + CA K K
Sbjct: 58 DFQLMLKIRD--TLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHK 115
Query: 121 ETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDP 180
+ +C NFI+V V N ++ CGT AF+P C + L + + + G + PFD
Sbjct: 116 D-ECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEY----DGEEISGLARCPFDA 170
Query: 181 AHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNF-LRWLHHDASFVAAIPS 239
+ A+ DG LYS T+ +FL S+ ++ R++G L+T + +W+ + F+ AI
Sbjct: 171 RQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIK-EPHFLHAIEY 229
Query: 240 TQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGG-EKLLQKKWTTFLKAQLLCTQPGQ 298
VYFFF E A E + + SRVAR+CKND+GG +++L+K WT+FLKA+L C+ PG
Sbjct: 230 GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGD 289
Query: 299 LPFNV-IRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKEL 357
F + ++ P + VFT+ Q+ SAVCAFS+ DIE+VFKG++KE
Sbjct: 290 SFFYFDVLQSITDIIQINGIPTVVGVFTT--QLNSIPGSAVCAFSMDDIEKVFKGRFKEQ 347
Query: 358 NKETSRWTTYRGPE---TNPRPGSCSVGPSS----------DKALTFMKDHFLMDEQV-- 402
S WT PE PRPG C+ + D+ L+F+K H LMD V
Sbjct: 348 KTPDSVWTAV--PEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPP 405
Query: 403 -VGTPLLVKSGVEY--TRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGD----SSAH 455
P K+ V Y T ++V+ + G ++ V+++G+ G + K + + +
Sbjct: 406 IADEPWFTKTRVRYRLTAISVDHSAG-PYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSV 464
Query: 456 LVEEIQLF---------PDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESC-VD 505
L+EEI+ + + + V +LQL A++V FS + R+P + C Y SC
Sbjct: 465 LLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKS 524
Query: 506 CVLARDPHCAWDPESRTCCLLSAPNL--NSWKQDMERGN 542
C+ +RDP+C W S+ C P + ++QD E GN
Sbjct: 525 CIASRDPYCGW--LSQGSCGRVTPGMLAEGYEQDTEFGN 561
>gi|24234735 semaphorin 6D isoform 2 precursor [Homo sapiens]
Length = 998
Score = 233 bits (594), Expect = 5e-61
Identities = 167/519 (32%), Positives = 265/519 (51%), Gaps = 54/519 (10%)
Query: 63 DFDTLLLSGDGNTLYVGAREAILALDIQD-PGVPRLKNM-IPWPASDRKKSECAFKKKSN 120
DF +L D TLY+ R+ + +++ + P + N + W + + + CA K K
Sbjct: 58 DFQLMLKIRD--TLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHK 115
Query: 121 ETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDP 180
+ +C NFI+V V N ++ CGT AF+P C + L + + + G + PFD
Sbjct: 116 D-ECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEY----DGEEISGLARCPFDA 170
Query: 181 AHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNF-LRWLHHDASFVAAIPS 239
+ A+ DG LYS T+ +FL S+ ++ R++G L+T + +W+ + F+ AI
Sbjct: 171 RQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIK-EPHFLHAIEY 229
Query: 240 TQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGG-EKLLQKKWTTFLKAQLLCTQPGQ 298
VYFFF E A E + + SRVAR+CKND+GG +++L+K WT+FLKA+L C+ PG
Sbjct: 230 GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGD 289
Query: 299 LPFNV-IRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKEL 357
F + ++ P + VFT+ Q+ SAVCAFS+ DIE+VFKG++KE
Sbjct: 290 SFFYFDVLQSITDIIQINGIPTVVGVFTT--QLNSIPGSAVCAFSMDDIEKVFKGRFKEQ 347
Query: 358 NKETSRWTTYRGPE---TNPRPGSCSVGPSS----------DKALTFMKDHFLMDEQV-- 402
S WT PE PRPG C+ + D+ L+F+K H LMD V
Sbjct: 348 KTPDSVWTAV--PEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPP 405
Query: 403 -VGTPLLVKSGVEY--TRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGD----SSAH 455
P K+ V Y T ++V+ + G ++ V+++G+ G + K + + +
Sbjct: 406 IADEPWFTKTRVRYRLTAISVDHSAG-PYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSV 464
Query: 456 LVEEIQLF---------PDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESC-VD 505
L+EEI+ + + + V +LQL A++V FS + R+P + C Y SC
Sbjct: 465 LLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKS 524
Query: 506 CVLARDPHCAWDPESRTCCLLSAPNL--NSWKQDMERGN 542
C+ +RDP+C W S+ C P + ++QD E GN
Sbjct: 525 CIASRDPYCGW--LSQGSCGRVTPGMLAEGYEQDTEFGN 561
>gi|24234729 semaphorin 6D isoform 1 precursor [Homo sapiens]
Length = 1011
Score = 229 bits (584), Expect = 7e-60
Identities = 159/491 (32%), Positives = 253/491 (51%), Gaps = 50/491 (10%)
Query: 63 DFDTLLLSGDGNTLYVGAREAILALDIQD-PGVPRLKNM-IPWPASDRKKSECAFKKKSN 120
DF +L D TLY+ R+ + +++ + P + N + W + + + CA K K
Sbjct: 58 DFQLMLKIRD--TLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHK 115
Query: 121 ETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDP 180
+ +C NFI+V V N ++ CGT AF+P C + L + + + G + PFD
Sbjct: 116 D-ECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEY----DGEEISGLARCPFDA 170
Query: 181 AHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNF-LRWLHHDASFVAAIPS 239
+ A+ DG LYS T+ +FL S+ ++ R++G L+T + +W+ + F+ AI
Sbjct: 171 RQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIK-EPHFLHAIEY 229
Query: 240 TQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGG-EKLLQKKWTTFLKAQLLCTQPGQ 298
VYFFF E A E + + SRVAR+CKND+GG +++L+K WT+FLKA+L C+ PG
Sbjct: 230 GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGD 289
Query: 299 LPFNV-IRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKEL 357
F + ++ P + VFT+ Q+ SAVCAFS+ DIE+VFKG++KE
Sbjct: 290 SFFYFDVLQSITDIIQINGIPTVVGVFTT--QLNSIPGSAVCAFSMDDIEKVFKGRFKEQ 347
Query: 358 NKETSRWTTYRGPE---TNPRPGSCSVGPSS----------DKALTFMKDHFLMDEQV-- 402
S WT PE PRPG C+ + D+ L+F+K H LMD V
Sbjct: 348 KTPDSVWTAV--PEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPP 405
Query: 403 -VGTPLLVKSGVEY--TRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGD----SSAH 455
P K+ V Y T ++V+ + G ++ V+++G+ G + K + + +
Sbjct: 406 IADEPWFTKTRVRYRLTAISVDHSAG-PYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSV 464
Query: 456 LVEEIQLF---------PDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESC-VD 505
L+EEI+ + + + V +LQL A++V FS + R+P + C Y SC
Sbjct: 465 LLEEIEAYNHAKCSAENEEDKKVISLQLDKDHHALYVAFSSCIIRIPLSRCERYGSCKKS 524
Query: 506 CVLARDPHCAW 516
C+ +RDP+C W
Sbjct: 525 CIASRDPYCGW 535
>gi|16306552 semaphorin Y [Homo sapiens]
Length = 930
Score = 218 bits (554), Expect = 2e-56
Identities = 179/554 (32%), Positives = 271/554 (48%), Gaps = 67/554 (12%)
Query: 18 LFQLLQLLLPTTTAGGGGQGPMPRV----------RYYAGDERRALSFFHQKGLQDFDTL 67
L LL L LP T A Q P+P + ++ G E A++ Q F TL
Sbjct: 11 LLLLLLLSLPHTQAAFP-QDPLPLLISDLQGTSPLSWFRGLEDDAVAAELGLDFQRFLTL 69
Query: 68 LLSGDGNTLYVGAREAILALDIQ--DPGVPRLKNM-IPWPASDRKKSECAFKKKSNETQC 124
TL V AR+ + + D+Q + G + N + W + D + CA + K + +C
Sbjct: 70 -----NRTLLVAARDHVFSFDLQAEEEGEGLVPNKYLTWRSQDVEN--CAVRGKLTD-EC 121
Query: 125 FNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDPAHKH 184
+N+IRVLV ++ L CGT +FSP C + E + + G+ + PFD +
Sbjct: 122 YNYIRVLVPWDSQTLLACGTNSFSPVCRSYGITSLQ----QEGEELSGQARCPFDATQSN 177
Query: 185 TAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNF-LRWLHHDASFVAAIPSTQVV 243
A+ +G LYS T +F S+ ++ R+LG QP L++ + +WL + FV A+ V
Sbjct: 178 VAIFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLR-EPHFVQALEHGDHV 236
Query: 244 YFFFEETASEFDFFERLHTSRVARVCKNDVGGE-KLLQKKWTTFLKAQLLCTQPGQLPFN 302
YFFF E + E R+ SRVARVCK D+GG + L + WT+FLK +L C+ PG F
Sbjct: 237 YFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFY 296
Query: 303 V-IRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKELNKET 361
+ A+ P + ++ VFT+ Q SAVCAF L +IER F+GK+KE
Sbjct: 297 FDVLQALTGPVNLHGRSALFGVFTT--QTNSIPGSAVCAFYLDEIERGFEGKFKEQRSLD 354
Query: 362 SRWTTYRGPET-NPRPGSCS-VGPSS---------DKALTFMKDHFLMDEQVVGTPLLVK 410
WT +PRPGSC+ VG ++ D LTF+K H L+D V P+ +
Sbjct: 355 GAWTPVSEDRVPSPRPGSCAGVGGAALFSSSRDLPDDVLTFIKAHPLLDPAV--PPVTHQ 412
Query: 411 SGVEYTRLAVETAQGLDG----HSHL-VMYLGTTTGSLHKAVVSGDSSAH----LVEEIQ 461
+ T A+ T +DG HS++ VM+LG+ G++ K + G S L+EEI
Sbjct: 413 PLLTLTSRALLTQVAVDGMAGPHSNITVMFLGSNDGTVLKVLTPGGRSGGPEPILLEEID 472
Query: 462 LF-----------PDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVYESCV-DCVLA 509
+ + L+L +FV FSG + +P + C+ + +C C+ +
Sbjct: 473 AYSPARCSGKRTAQTARRIIGLELDTEGHRLFVAFSGCIVYLPLSRCARHGACQRSCLAS 532
Query: 510 RDPHCAWDPESRTC 523
+DP+C W SR C
Sbjct: 533 QDPYCGWH-SSRGC 545
>gi|24234732 semaphorin 6D isoform 6 precursor [Homo sapiens]
Length = 476
Score = 197 bits (500), Expect = 4e-50
Identities = 139/428 (32%), Positives = 222/428 (51%), Gaps = 40/428 (9%)
Query: 63 DFDTLLLSGDGNTLYVGAREAILALDIQD-PGVPRLKNM-IPWPASDRKKSECAFKKKSN 120
DF +L D TLY+ R+ + +++ + P + N + W + + + CA K K
Sbjct: 58 DFQLMLKIRD--TLYIAGRDQVYTVNLNEMPKTEVIPNKKLTWRSRQQDRENCAMKGKHK 115
Query: 121 ETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDP 180
+ +C NFI+V V N ++ CGT AF+P C + L + + + G + PFD
Sbjct: 116 D-ECHNFIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLEY----DGEEISGLARCPFDA 170
Query: 181 AHKHTAVLVDGMLYSGTMNNFLGSEPILMRTLGSQPVLKTDNF-LRWLHHDASFVAAIPS 239
+ A+ DG LYS T+ +FL S+ ++ R++G L+T + +W+ + F+ AI
Sbjct: 171 RQTNVALFADGKLYSATVADFLASDAVIYRSMGDGSALRTIKYDSKWIK-EPHFLHAIEY 229
Query: 240 TQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGG-EKLLQKKWTTFLKAQLLCTQPGQ 298
VYFFF E A E + + SRVAR+CKND+GG +++L+K WT+FLKA+L C+ PG
Sbjct: 230 GNYVYFFFREIAVEHNNLGKAVYSRVARICKNDMGGSQRVLEKHWTSFLKARLNCSVPGD 289
Query: 299 LPFNV-IRHAVLLPADSPTAPHIYAVFTSQWQVGGTRSSAVCAFSLLDIERVFKGKYKEL 357
F + ++ P + VFT+ Q+ SAVCAFS+ DIE+VFKG++KE
Sbjct: 290 SFFYFDVLQSITDIIQINGIPTVVGVFTT--QLNSIPGSAVCAFSMDDIEKVFKGRFKEQ 347
Query: 358 NKETSRWTTYRGPE---TNPRPGSCSVGPSS----------DKALTFMKDHFLMDEQV-- 402
S WT PE PRPG C+ + D+ L+F+K H LMD V
Sbjct: 348 KTPDSVWTAV--PEDKVPKPRPGCCAKHGLAEAYKTSIDFPDETLSFIKSHPLMDSAVPP 405
Query: 403 -VGTPLLVKSGVEY--TRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGD----SSAH 455
P K+ V Y T ++V+ + G ++ V+++G+ G + K + + +
Sbjct: 406 IADEPWFTKTRVRYRLTAISVDHSAG-PYQNYTVIFVGSEAGMVLKVLAKTSPFSLNDSV 464
Query: 456 LVEEIQLF 463
L+EEI+ +
Sbjct: 465 LLEEIEAY 472
>gi|225637520 semaphorin 7A isoform 2 preproprotein [Homo sapiens]
Length = 652
Score = 166 bits (420), Expect = 7e-41
Identities = 173/607 (28%), Positives = 259/607 (42%), Gaps = 87/607 (14%)
Query: 116 KKKSNETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQ 175
K S T C N+I L+ L CGT A P+C L + ++P+ E + G
Sbjct: 104 KNASVRTDCENYI-TLLERRSEGLLACGTNARHPSCW--NLVNGTVVPLGEMR-----GY 155
Query: 176 SPFDPAHKHTAVLVDGMLYSGTMNN--FLGSEPILMRTLG------SQPVLKTDNFLRW- 226
+PF P +++ VL +G T+ + G P R G S V++ F++
Sbjct: 156 APFSP-DENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKAT 214
Query: 227 -LHHDASFVAAIPSTQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGEKLLQ-KKWT 284
+H D ++ +Y+FF E + + L+ SRVA++C+ D GGE L KW
Sbjct: 215 IVHQDQAY------DDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWN 268
Query: 285 TFLKAQLLCTQPG-QLPFNVIRHAVLLPADSP--TAPHIYAVFTSQWQVGGTRSSAVCAF 341
TFLKA L+C+ FN ++ LLP S +Y VF++ W SAVC +
Sbjct: 269 TFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY-----SAVCVY 323
Query: 342 SLLDIERVFKGKYKELNKETSRWTTYRGPETNPRPGSC--SVGPSSDKALTFMKDHFLMD 399
SL DI++VF+ TS Y NPRPG C P + H +
Sbjct: 324 SLGDIDKVFR---------TSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVA 374
Query: 400 EQV-----VGTPLLVKSGVEYTRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGD--- 451
++V + TPL S Y ++AV Q G + V+YL T G++HK V G+
Sbjct: 375 QRVEPMGPLKTPLF-HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEH 433
Query: 452 SSAHLVEEIQLFPDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVY-ESCVDCVLAR 510
S A + EIQ F ++ + L + ++V V +VP C VY C C+++R
Sbjct: 434 SFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSR 493
Query: 511 DPHCAWDPESRTCCLLSAPNLNSWKQDMERGNPEWACASGPMSRSLRPQSRPQIIKEVLA 570
DP+C WD + C+ + S Q + P C + +P P +++V
Sbjct: 494 DPYCGWD---QGRCISIYSSERSVLQSINPAEPHKECPNP------KPDKAP--LQKVSL 542
Query: 571 VPNSILELPCPHLSALASYYWSHGPAAVPEASSTVYNGSLLLIVQDGVG---GLYQCWAT 627
PNS L CP S A+Y W H + + +L +++ G Y C A
Sbjct: 543 APNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFIENLTAQQYGHYFCEAQ 602
Query: 628 ENGFSYPVISYWVDSQDQTLALDPELAGIPREHVKVPLTRVSGGAALAAQQSYWPHFVTV 687
E SY+ ++Q L PE GI EH+ G A A S W +
Sbjct: 603 EG-------SYFREAQHWQLL--PE-DGIMAEHLL--------GHACALAASLWLGVLPT 644
Query: 688 TVLFALV 694
L LV
Sbjct: 645 LTLGLLV 651
>gi|4504237 semaphorin 7A isoform 1 preproprotein [Homo sapiens]
Length = 666
Score = 164 bits (416), Expect = 2e-40
Identities = 201/722 (27%), Positives = 304/722 (42%), Gaps = 114/722 (15%)
Query: 10 PWSLLGLFLFQLLQLLLPTTTAGGGGQGPM---PRV----RYYAGDERRALSFFHQKGLQ 62
P + LGL L L+LLL A QG + PR+ + + G +R + F G
Sbjct: 21 PPARLGLPL--RLRLLLLLWAAAASAQGHLRSGPRIFAVWKGHVGQDR--VDF----GQT 72
Query: 63 DFDTLLLSGDGNT-LYVGAREAILALDIQDPGVPRLKNMIPWPAS-DRKKSECAFKKKSN 120
+ T+L G++ ++VG R + D P KN + K C K+
Sbjct: 73 EPHTVLFHEPGSSSVWVGGRGKVYLFDF-----PEGKNASVRTVNIGSTKGSCLDKR--- 124
Query: 121 ETQCFNFIRVLVSYNVTHLYTCGTFAFSPACTFIELQDSYLLPISEDKVMEGKGQSPFDP 180
C N+I L+ L CGT A P+C L + ++P+ E + G +PF P
Sbjct: 125 --DCENYI-TLLERRSEGLLACGTNARHPSCW--NLVNGTVVPLGEMR-----GYAPFSP 174
Query: 181 AHKHTAVLVDGMLYSGTMNN--FLGSEPILMRTLG------SQPVLKTDNFLRW--LHHD 230
+++ VL +G T+ + G P R G S V++ F++ +H D
Sbjct: 175 -DENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFIKATIVHQD 233
Query: 231 ASFVAAIPSTQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGEKLLQ-KKWTTFLKA 289
++ +Y+FF E + + L+ SRVA++C+ D GGE L KW TFLKA
Sbjct: 234 QAY------DDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVSKWNTFLKA 287
Query: 290 QLLCTQPG-QLPFNVIRHAVLLPADSP--TAPHIYAVFTSQWQVGGTRSSAVCAFSLLDI 346
L+C+ FN ++ LLP S +Y VF++ W SAVC +SL DI
Sbjct: 288 MLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY-----SAVCVYSLGDI 342
Query: 347 ERVFKGKYKELNKETSRWTTYRGPETNPRPGSC--SVGPSSDKALTFMKDHFLMDEQV-- 402
++VF+ TS Y NPRPG C P + H + ++V
Sbjct: 343 DKVFR---------TSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHPEVAQRVEP 393
Query: 403 ---VGTPLLVKSGVEYTRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGD---SSAHL 456
+ TPL S Y ++AV Q G + V+YL T G++HK V G+ S A
Sbjct: 394 MGPLKTPLF-HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGEQEHSFAFN 452
Query: 457 VEEIQLFPDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVY-ESCVDCVLARDPHCA 515
+ EIQ F ++ + L + ++V V +VP C VY C C+++RDP+C
Sbjct: 453 IMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCLMSRDPYCG 512
Query: 516 WDPESRTCCLLSAPNLNSWKQDMERGNPEWACASGPMSRSLRPQSRPQIIKEVLAVPNSI 575
WD + C+ + S Q + P C + +P P +++V PNS
Sbjct: 513 WD---QGRCISIYSSERSVLQSINPAEPHKECPNP------KPDKAP--LQKVSLAPNSR 561
Query: 576 LELPCPHLSALASYYWSHGPAAVPEASSTVYNGSLLLIVQDGVG---GLYQCWATENGFS 632
L CP S A+Y W H + + +L +++ G Y C A E
Sbjct: 562 YYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFIENLTAQQYGHYFCEAQEG--- 618
Query: 633 YPVISYWVDSQDQTLALDPELAGIPREHVKVPLTRVSGGAALAAQQSYWPHFVTVTVLFA 692
SY+ ++Q L PE GI EH+ G A A S W + L
Sbjct: 619 ----SYFREAQHWQLL--PE-DGIMAEHLL--------GHACALAASLWLGVLPTLTLGL 663
Query: 693 LV 694
LV
Sbjct: 664 LV 665
>gi|225637524 semaphorin 7A isoform 3 [Homo sapiens]
Length = 501
Score = 152 bits (385), Expect = 9e-37
Identities = 156/550 (28%), Positives = 235/550 (42%), Gaps = 79/550 (14%)
Query: 173 KGQSPFDPAHKHTAVLVDGMLYSGTMNN--FLGSEPILMRTLG------SQPVLKTDNFL 224
+G +PF P +++ VL +G T+ + G P R G S V++ F+
Sbjct: 2 RGYAPFSP-DENSLVLFEGDEVYSTIRKQEYNGKIPRFRRIRGESELYTSDTVMQNPQFI 60
Query: 225 RW--LHHDASFVAAIPSTQVVYFFFEETASEFDFFERLHTSRVARVCKNDVGGEKLLQ-K 281
+ +H D ++ +Y+FF E + + L+ SRVA++C+ D GGE L
Sbjct: 61 KATIVHQDQAY------DDKIYYFFREDNPDKNPEAPLNVSRVAQLCRGDQGGESSLSVS 114
Query: 282 KWTTFLKAQLLCTQPG-QLPFNVIRHAVLLPADSP--TAPHIYAVFTSQWQVGGTRSSAV 338
KW TFLKA L+C+ FN ++ LLP S +Y VF++ W SAV
Sbjct: 115 KWNTFLKAMLVCSDAATNKNFNRLQDVFLLPDPSGQWRDTRVYGVFSNPWNY-----SAV 169
Query: 339 CAFSLLDIERVFKGKYKELNKETSRWTTYRGPETNPRPGSC--SVGPSSDKALTFMKDHF 396
C +SL DI++VF+ TS Y NPRPG C P + H
Sbjct: 170 CVYSLGDIDKVFR---------TSSLKGYHSSLPNPRPGKCLPDQQPIPTETFQVADRHP 220
Query: 397 LMDEQV-----VGTPLLVKSGVEYTRLAVETAQGLDGHSHLVMYLGTTTGSLHKAVVSGD 451
+ ++V + TPL S Y ++AV Q G + V+YL T G++HK V G+
Sbjct: 221 EVAQRVEPMGPLKTPLF-HSKYHYQKVAVHRMQASHGETFHVLYLTTDRGTIHKVVEPGE 279
Query: 452 ---SSAHLVEEIQLFPDPEPVRNLQLAPTQGAVFVGFSGGVWRVPRANCSVY-ESCVDCV 507
S A + EIQ F ++ + L + ++V V +VP C VY C C+
Sbjct: 280 QEHSFAFNIMEIQPFRRAAAIQTMSLDAERRKLYVSSQWEVSQVPLDLCEVYGGGCHGCL 339
Query: 508 LARDPHCAWDPESRTCCLLSAPNLNSWKQDMERGNPEWACASGPMSRSLRPQSRPQIIKE 567
++RDP+C WD + C+ + S Q + P C + +P P +++
Sbjct: 340 MSRDPYCGWD---QGRCISIYSSERSVLQSINPAEPHKECPNP------KPDKAP--LQK 388
Query: 568 VLAVPNSILELPCPHLSALASYYWSHGPAAVPEASSTVYNGSLLLIVQDGVG---GLYQC 624
V PNS L CP S A+Y W H + + +L +++ G Y C
Sbjct: 389 VSLAPNSRYYLSCPMESRHATYSWRHKENVEQSCEPGHQSPNCILFIENLTAQQYGHYFC 448
Query: 625 WATENGFSYPVISYWVDSQDQTLALDPELAGIPREHVKVPLTRVSGGAALAAQQSYWPHF 684
A E SY+ ++Q L PE GI EH+ G A A S W
Sbjct: 449 EAQEG-------SYFREAQHWQLL--PE-DGIMAEHLL--------GHACALAASLWLGV 490
Query: 685 VTVTVLFALV 694
+ L LV
Sbjct: 491 LPTLTLGLLV 500
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,800,920
Number of Sequences: 37866
Number of extensions: 1532550
Number of successful extensions: 3647
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 3359
Number of HSP's gapped (non-prelim): 64
length of query: 761
length of database: 18,247,518
effective HSP length: 110
effective length of query: 651
effective length of database: 14,082,258
effective search space: 9167549958
effective search space used: 9167549958
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.